AutismKB 2.0

Annotation Detail for BIK


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Basic Information Top
Gene Symbol:BIK ( BIP1,BP4,NBK )
Gene Full Name: BCL2-interacting killer (apoptosis-inducing)
Band: 22q13.2
Quick LinksEntrez ID:638; OMIM: 603392; Uniprot ID:BIK_HUMAN; ENSEMBL ID: ENSG00000100290; HGNC ID: 1051
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
P00006Apoptosis signaling pathway
No data
Related Diseases/Disorders Top
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Desease IDDesease Name
1944Breast cancer
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C031278 2-chloroethyl ethyl sulfide 2-chloroethyl ethyl sulfide results in decreased expression of BIK mRNAdecreases expression 12208782
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of BIK mRNAdecreases expression 18648102
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of BIK proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride affects the expression of BIK mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in increased expression of BIK mRNAincreases expression 19730151
D001374 Azacitidine [Azacitidine co-treated with N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide] results in increased expression of BIK mRNAaffects cotreatment|increases expression 21224363
D001374 Azacitidine Azacitidine results in increased expression of BIK mRNAincreases expression 21224363
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of BIK mRNAincreases expression 20106945
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of BIK mRNAdecreases expression 19150397
D002251 Carbon Tetrachloride [Ethanol co-treated with pyrazole co-treated with Carbon Tetrachloride] results in increased expression of BIK mRNAaffects cotreatment|increases expression 16610055
D002784 Cholesterol Cholesterol analog results in increased expression of BIK mRNAincreases expression 19477266
D003024 Clozapine Clozapine results in increased expression of BIK mRNAincreases expression 16160616
D003024 Clozapine CSF3 protein inhibits the reaction [Clozapine results in increased expression of BIK mRNA]decreases reaction|increases expression 16160616
D003042 Cocaine Cocaine affects the expression of BIK mRNAaffects expression 15681117
D003520 Cyclophosphamide Cyclophosphamide results in decreased expression of BIK mRNAdecreases expression 17403535
C014347 decitabine [decitabine co-treated with Depsipeptides] results in increased expression of BIK mRNAaffects cotreatment|increases expression 17064661
C014347 decitabine decitabine results in increased expression of BIK proteinincreases expression 17064661
C014347 decitabine Depsipeptides promotes the reaction [decitabine results in increased expression of BIK protein]increases expression|increases reaction 17064661
D047630 Depsipeptides [decitabine co-treated with Depsipeptides] results in increased expression of BIK mRNAaffects cotreatment|increases expression 17064661
D047630 Depsipeptides Depsipeptides promotes the reaction [decitabine results in increased expression of BIK protein]increases expression|increases reaction 17064661
D047630 Depsipeptides Depsipeptides results in increased expression of BIK mRNAincreases expression 17064661
D047630 Depsipeptides Depsipeptides results in increased expression of BIK proteinincreases expression 17064661
D004317 Doxorubicin BIK protein results in increased susceptibility to Doxorubicinincreases response to substance 16007125
D004317 Doxorubicin Doxorubicin results in decreased expression of BIK mRNAdecreases expression 16705698
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of BIK mRNAaffects cotreatment|increases expression 19619570
D004958 Estradiol Estradiol results in decreased expression of BIK mRNAdecreases expression 19619570
D004958 Estradiol Estradiol results in increased expression of BIK proteinincreases expression 17638070
D000431 Ethanol [Ethanol co-treated with pyrazole co-treated with Carbon Tetrachloride] results in increased expression of BIK mRNAaffects cotreatment|increases expression 16610055
D005047 Etoposide BIK protein results in increased susceptibility to Etoposideincreases response to substance 16007125
D005419 Flavonoids Flavonoids results in increased expression of BIK mRNAincreases expression 18035473
D005665 Furosemide Furosemide affects the expression of BIK mRNAaffects expression 17497460
C118739 N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide [Azacitidine co-treated with N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide] results in increased expression of BIK mRNAaffects cotreatment|increases expression 21224363
C076029 olanzapine olanzapine results in increased expression of BIK mRNAincreases expression 16160616
C019248 pamidronate BIK protein results in increased susceptibility to pamidronateincreases response to substance 16007125
D010634 Phenobarbital Phenobarbital results in increased expression of BIK mRNAincreases expression 19482888
C031280 pyrazole [Ethanol co-treated with pyrazole co-treated with Carbon Tetrachloride] results in increased expression of BIK mRNAaffects cotreatment|increases expression 16610055
D018038 Sodium Selenite Sodium Selenite results in decreased expression of BIK mRNAdecreases expression 18175754
D013629 Tamoxifen ESR2 protein promotes the reaction [Tamoxifen results in increased expression of BIK protein]increases expression|increases reaction 17638070
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of BIK mRNAaffects cotreatment|increases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of BIK mRNAdecreases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of BIK mRNAincreases expression 20106945
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin affects the expression of BIK mRNAaffects expression 14718646
D014520 Urethane Urethane results in increased expression of BIK mRNAincreases expression 16978161
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.2614745880
MESH:D000014 Abnormalities, Drug-Induced Ethanol 12.6317676605 18926900
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 12.636195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 12.6314514962 11752688 15322242
MESH:D000138 Acidosis Ammonium Chloride 9.5418287403
MESH:D000138 Acidosis Ethanol 9.5411192467
MESH:D000230 Adenocarcinoma arsenic trioxide 12.7611798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 12.7620464547 20127859
MESH:D000230 Adenocarcinoma Doxorubicin 12.7617418594
MESH:D000230 Adenocarcinoma Estradiol 12.7611473722
MESH:D000230 Adenocarcinoma Urethane 12.7618316556
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Urethane 5.4315814487
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 10.343712494
MESH:D000236 Adenoma Benzo(a)pyrene 10.346695378
MESH:D000236 Adenoma Urethane 10.3410822126 16926031 6695378 10530776 17195641 11497255 17093202
MESH:D018248 Adenoma, Liver Cell Phenobarbital 9.1517620307
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.1516835633
MESH:D000380 Agranulocytosis Clozapine 4.7814617031 12649775 16160616
MESH:D000419 Albuminuria Doxorubicin 4.2821441931
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 5.0315451039 15451040
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.7111748828
MESH:D000853 Anophthalmos Ethanol 4.5515513904
MESH:D001008 Anxiety Disorders Ethanol 3.7911141031
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.8019183758
MESH:D001161 Arteriosclerosis Cyclophosphamide 4.3315014928
MESH:D050197 Atherosclerosis Cholesterol 4.0816632123
MESH:D001321 Autistic Disorder olanzapine 3.3917069543 18685284
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.731440618 11289319
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 8.1316206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.1312125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.5115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.5915746008
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 11.2114601052
MESH:D019046 Bone Marrow Neoplasms Etoposide 11.2114601052
MESH:D001862 Bone Resorption pamidronate 5.6515845617 8053405
MESH:D001932 Brain Neoplasms Doxorubicin 3.5717150277
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 4.4917474063 20146248
MESH:D001943 Breast Neoplasms Cyclophosphamide 4.4916978400 11325840 17020986 18323546 17388661 15136595 18234424 15093573 12006526
MESH:D001943 Breast Neoplasms decitabine 4.4918320071 19208741
MESH:D001943 Breast Neoplasms Doxorubicin 4.4918628466 15136595 16096432 19526202 11325840 15567936 16115903 17426702 17369602 16595493 17983394 16264153 15692762 16935488 15668708 18695136 15993339 16322301 18234424 15939500 16826403 15634643 15994142 18382427
MESH:D001943 Breast Neoplasms Estradiol 4.4912948864 16675129 17018787 17261762 19861407 14630087 17289903 18497071
MESH:D001943 Breast Neoplasms Etoposide 4.4916322251
MESH:D001943 Breast Neoplasms Tamoxifen 4.4921138602 18997820 20859285 20065188 19011961 18351453 19200415 17440819 19410462 19142967 17261762 18855134 21152245 16873071 19084267 19066611 19288272 19244106 20390343 17242785 17893378 18425577 20135344 19487384 18815881 16273361 18629630 18984771 19221464 18821012 19155303 17049068 20544844 19059307 19115204 19289846 19189212 16202921 11161223 19103187 19189210 16818667 15565566 20005174 15668708
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 4.4920435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.0711589617
MESH:D002056 Burns Ethanol 4.3816374292
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.1816111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.5116192424 16097048 3786805 16124888 15721981 16050911 16227642 18705752 15700767 16011737 15673190 10355542
MESH:D002276 Carcinoid Tumor Doxorubicin 4.5316051944
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.5816835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.2319066611
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 21.947296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 21.9421507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 21.9415553829 11135700 16217749 15073043 14691202
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 21.9418788625
MESH:D006528 Carcinoma, Hepatocellular Cyclophosphamide 21.9419701751
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 21.9418059187 16234567 17876044 16023760
MESH:D006528 Carcinoma, Hepatocellular Estradiol 21.9416924424
MESH:D006528 Carcinoma, Hepatocellular Ethanol 21.9415289165 18788625 15763234
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 21.9420935162 1701930 6705139 20007298 17173139
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 21.9416924424
MESH:D018827 Carcinoma, Lewis Lung Cyclophosphamide 4.6116152834
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.5919014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 10.097296757
MESH:D002292 Carcinoma, Renal Cell Cyclophosphamide 10.0916201981
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 10.0916201981 1485588
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.8812490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 7.0820419170
MESH:D002294 Carcinoma, Squamous Cell decitabine 7.0819215824
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 7.086189445
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.3717572228
MESH:D006332 Cardiomegaly Ethanol 6.3319332462
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.3318670907 18850075 16120746
MESH:D009202 Cardiomyopathies Doxorubicin 3.3516364871 17308081 17329180 17924179 17131338 16455267 18627295 17382496 16651473 16242529 17351982 16612575 15792986 17007740 16731534 15476868 16278810 17519947 16952015 16109756 15505089 17928571 16269455 15811867 17974986
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.8516243910 17334414
MESH:D002389 Catatonia olanzapine 5.9718071103 16772815
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 10.067505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 10.0620889678
MESH:D002471 Cell Transformation, Neoplastic Estradiol 10.0618566989
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.984080065
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.9316835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 2.9419486331 9022650
MESH:D019457 Chromosome Breakage Sodium Selenite 4.4815894690
MESH:D002971 Cleft Lip Ethanol 3.4415513904
MESH:D002972 Cleft Palate Ethanol 9.3015513904
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 9.3015340226 8697196 15668235 12621046 16354765
MESH:D002972 Cleft Palate Urethane 9.3012810352
MESH:D019970 Cocaine-Related Disorders Cocaine 5.4419606084
MESH:D003072 Cognition Disorders Clozapine 4.6917123785
MESH:D003110 Colonic Neoplasms decitabine 2.2917616700
MESH:D015179 Colorectal Neoplasms arsenic trioxide 4.6120501625
MESH:D015179 Colorectal Neoplasms Azacitidine 4.6119934284
MESH:D015179 Colorectal Neoplasms decitabine 4.6118981723
MESH:D015179 Colorectal Neoplasms Doxorubicin 4.6118259882 18802399
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.8317141729 14669216
MESH:D023903 Coronary Restenosis arsenic trioxide 3.9212609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.6410525206
MESH:D019465 Craniofacial Abnormalities Ethanol 3.6415451040 11198716 10194807 15451039 15513904 19302082 11873399
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.6420055451 15322242 10048152
MESH:D003556 Cystitis Cyclophosphamide 4.7011948286 18093676 10498854 15643279 15276878 16413132 16614059 12388444 18372110 16989017 10700343 16651033 17010015 18295254 12913760 18710439 17979934 18433785 18483878 12161096
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.8415213294
MESH:D003711 Demyelinating Diseases Tamoxifen 4.0919031437
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.5418759878 11906362 12868966 8970840 11298694 8156756 14531868 2524372
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.232952479 3621924
MESH:D002658 Developmental Disabilities olanzapine 4.5117069543
MESH:D003920 Diabetes Mellitus Sodium Selenite 3.5416285004
MESH:D003921 Diabetes Mellitus, Experimental Cyclophosphamide 3.8410990075 15331540 11751995
MESH:D003922 Diabetes Mellitus, Type 1 Cyclophosphamide 3.1318772604
MESH:D003924 Diabetes Mellitus, Type 2 Clozapine 4.2716402076
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.2717107852
MESH:D003928 Diabetic Nephropathies Estradiol 8.0619279558
MESH:D003928 Diabetic Nephropathies Tamoxifen 8.0619279558
MESH:D006970 Disorders of Excessive Somnolence Clozapine 5.2715331141
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 17.349022650 18648102 8291058 18692083 1440618 11289319 9328219 9653073 7440962 6482804 6679447 18289764 16192314
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 17.3415027814 6623471 6884620 4309450 7179309 3786805 2869522 7120509 10092053 15968718 19336974 9327722 11566570 3732212 10915739 15998439 21278145 17522070 16227642 19085960 16177239 7440962
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 17.3417416283
MESH:D056486 Drug-Induced Liver Injury Ethanol 17.3411566570
MESH:D056486 Drug-Induced Liver Injury pyrazole 17.3412499123
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 17.3415131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 17.3420420201
MESH:D004362 Drug Toxicity Doxorubicin 7.4318602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 7.4311462148
MESH:D050171 Dyslipidemias Clozapine 3.9916402076
MESH:D004417 Dyspnea Furosemide 4.6616935035
MESH:D004421 Dystonia Phenobarbital 3.751851702
MESH:D004487 Edema Furosemide 6.2811834646
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.2812711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.6215322242 16714409 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 3.2719031437
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.8319294695
MESH:D016889 Endometrial Neoplasms Doxorubicin 11.4217359293
MESH:D016889 Endometrial Neoplasms Estradiol 11.4211473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Tamoxifen 11.4216202921 17893378 20544844 19155303
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.7810568697 9294722
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.8718037988
MESH:D004802 Eosinophilia Cyclophosphamide 3.9411006010
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.833659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.593922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.7520417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.316401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.987750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.743659116
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 13.013581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 13.0120426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 13.0112903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 13.0116530937
MESH:D004938 Esophageal Neoplasms Ethanol 13.0116704527
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.8111564622
MESH:D005234 Fatty Liver arsenic trioxide 16.7715073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 16.7712795759 16239168 17595544 12631006 15959796 61145 16045604 19224547
MESH:D005234 Fatty Liver Ethanol 16.7716409862 18620774 19236843
MESH:D005234 Fatty Liver Tamoxifen 16.7719224547 14986274
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.3817920746
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.0716709447
MESH:D005310 Fetal Alcohol Syndrome Ethanol 5.0216946407 10194807 15451040 15513904
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.1811858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.736705139
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.2514745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 10.5119069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 10.5119069698
MESH:D005355 Fibrosis Carbon Tetrachloride 7.6918705752
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 7.6920067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.0016904648
MESH:D005756 Gastritis Ethanol 4.4115046732
MESH:D005909 Glioblastoma Doxorubicin 3.1717150277
MESH:D018316 Gliosarcoma Cyclophosphamide 5.2311389073
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.787505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.3110696789
MESH:D006086 Graft vs Host Disease Cyclophosphamide 4.7616376943 15172196 11014644
MESH:D006258 Head and Neck Neoplasms decitabine 7.3419215824
MESH:D006258 Head and Neck Neoplasms Doxorubicin 7.3415692506
MESH:D034381 Hearing Loss Furosemide 4.5917868369
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 5.9620471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 5.9611294989 10048152
MESH:D006331 Heart Diseases Doxorubicin 7.4616144979 16879835 16244371 14766674 16330681 16244372 17888722 16495754 12587719 17875725 18674790 18006777 16707910
MESH:D006331 Heart Diseases Urethane 7.4616046796
MESH:D006333 Heart Failure Doxorubicin 7.0417481944
MESH:D006333 Heart Failure Furosemide 7.0416011733 12660669 16845234
MESH:D006394 Hemangiosarcoma Doxorubicin 3.6515692506
MESH:D006467 Hemophilia A Cyclophosphamide 5.0211918545
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0911000095
MESH:D006504 Hepatic Veno-Occlusive Disease Cyclophosphamide 5.2514986274
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 8.346705139
MESH:D006505 Hepatitis Carbon Tetrachloride 8.3419110552 19900420
MESH:D006529 Hepatomegaly Phenobarbital 7.5316109766
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.5315340226 16120746 12621046
MESH:D006558 Herpes Genitalis Estradiol 4.7515709030
MESH:D006561 Herpes Simplex Etoposide 4.2810809021
MESH:D006689 Hodgkin Disease Cyclophosphamide 11.1216135485 17606976
MESH:D006689 Hodgkin Disease Doxorubicin 11.1218501091 15147373 17606976
MESH:D006689 Hodgkin Disease Etoposide 11.1218180244 17606976 16200630 16135485 15147373
MESH:D019584 Hot Flashes Estradiol 3.4717088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.768697196 18606429 16959395 15340226 16354765
MESH:D006930 Hyperalgesia Ethanol 3.5018783367
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.2516899240
MESH:D006934 Hypercalcemia Furosemide 4.8217652376
MESH:D053565 Hypercalciuria Furosemide 5.3717652376
MESH:D006937 Hypercholesterolemia Cholesterol 4.7216933029
MESH:D006948 Hyperkinesis Clozapine 4.6316046005
MESH:D006962 Hyperparathyroidism, Secondary Furosemide 5.5915086907
MESH:D006963 Hyperphagia olanzapine 5.9517933447
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.6715034207
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.8018850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.8115338365
MESH:D046110 Hypertension, Pregnancy-Induced Furosemide 5.0116612254
MESH:C537153 Hypomagnesemia primary Furosemide 5.3711041285
MESH:D007019 Hypoproteinemia Furosemide 5.5916096441
MESH:D007022 Hypotension Furosemide 4.3611041285
MESH:D007024 Hypotension, Orthostatic Furosemide 5.1315811171
MESH:D007154 Immune System Diseases Cyclophosphamide 5.0516076520
MESH:D007248 Infertility, Male Cyclophosphamide 6.5316517039 7193160
MESH:D007248 Infertility, Male decitabine 6.5317581917
MESH:D007249 Inflammation Flavonoids 7.4517296493
MESH:D007249 Inflammation Tamoxifen 7.4519457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 7.4512200463 12878042
MESH:D007333 Insulin Resistance Estradiol 6.8316627594 16393666
MESH:D007333 Insulin Resistance Sodium Selenite 6.8314714311
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.739022650 8074119
MESH:D007569 Jaw Abnormalities Ethanol 9.2915513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.2916580747
MESH:D007674 Kidney Diseases Doxorubicin 9.3515699352 16775033 15369732
MESH:D007674 Kidney Diseases Estradiol 9.3515618244
MESH:D007674 Kidney Diseases Furosemide 9.3511041285
MESH:D007676 Kidney Failure, Chronic Doxorubicin 3.9016707910
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 11.116582329
MESH:D007680 Kidney Neoplasms Estradiol 11.1115610895
MESH:D007680 Kidney Neoplasms Tamoxifen 11.1118625569
MESH:D007859 Learning Disorders Cholesterol 9.2617134702
MESH:D007859 Learning Disorders Ethanol 9.2615451040
MESH:D007938 Leukemia arsenic trioxide 13.8915070760
MESH:D007938 Leukemia Azacitidine 13.8919148494
MESH:D007938 Leukemia Cyclophosphamide 13.8910602166
MESH:D007938 Leukemia decitabine 13.8918980019 19235587
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.8716085563
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Cyclophosphamide 3.3817802794 17658394 17008537 18172266 18587576 17296974
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.5517077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.0316972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 7.9414633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Cyclophosphamide 7.9410373061
MESH:D007951 Leukemia, Myeloid arsenic trioxide 14.6819077051
MESH:D007951 Leukemia, Myeloid Azacitidine 14.6819077051
MESH:D007951 Leukemia, Myeloid decitabine 14.6819117987 18454857 17236224
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 5.9520471514 16968895 16467208 19850784 17050201
MESH:D015470 Leukemia, Myeloid, Acute Azacitidine 5.9517596541 18720364
MESH:D015470 Leukemia, Myeloid, Acute decitabine 5.9517679729 18704418 19010910 18206229 18460780 19387464
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.1818055864
MESH:D054429 Leukemia, Myelomonocytic, Juvenile Azacitidine 4.9319299654
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.0316330433 16112521 17869043 17649720 17712046 19035177 16331271 19642359 9834237 16823087 12712474 17107899 15748426 11468182 12018890 16891316 15336539 19075265 17217047 16966277 12679006 11161223 15622746 15213294 19225113
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.0916882451
MESH:D007970 Leukopenia Cyclophosphamide 4.6910052129 11830472
MESH:D017880 Limb Deformities, Congenital Ethanol 3.6217676605
MESH:D008064 Lipidoses Clozapine 7.4217567588
MESH:D008064 Lipidoses Tamoxifen 7.4215342952 17567588
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 10.2016943688 17174718 11408273 17157831 16221502 11903743 16239168 17334410 21278145
MESH:D008103 Liver Cirrhosis Ethanol 10.2015289165
MESH:D008103 Liver Cirrhosis Phenobarbital 10.2021047994
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.8218295389
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.0215034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 8.2517805973 18006644 18376398 16015684 17631135 14512876 12958196 16248980 16192424 18277467 18251166 14724832 17714472 16116963 18187930 16638106 18412020 20821823 15818738 18395914 15338365 14716496 18210741 11481614 17761835 18166357 17708605 15931870 17766677 15925388 12632512 17823541 13678700 17944888 16097048 15650968 18418968 12649538 18395095 18472094 12609069 15057751 18420326 12898905 16011737 17869086 17525996 15893842 17976157 17565644 12667390 18481824 15959796 18317297 18429990 17481882 12586293 17698563 18156304 15730626 10355542 18054572 14716833 16136751 18263696 17557913 15123356 14620537 17721639 17922224 18279442 12445418 16027843 18472332 18339082 15370692 18205269 14748882 15996030 12389079 15052691 12632514 16033810 18705752 12741479 12666154 12445421 15673190 17640975 12546737 15362042 17900296 15876570
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 8.2516439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 8.2514716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 8.2518166357
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 8.2518564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 8.2512878042
MESH:D008107 Liver Diseases Carbon Tetrachloride 3.8516246199 16964402 15720792 17285989 15830285
MESH:D008107 Liver Diseases Phenobarbital 3.8519363144
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.3817347304 17207112
MESH:D017093 Liver Failure Carbon Tetrachloride 3.8915123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.4514706259 16899240
MESH:D008113 Liver Neoplasms Aflatoxin B1 24.059163691 15890375 2125692 18177683
MESH:D008113 Liver Neoplasms arsenic trioxide 24.0514682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 24.0520195826 21137059
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 24.0519294768
MESH:D008113 Liver Neoplasms Phenobarbital 24.058742319 15975961 19482888 19073162 21047994 19812893
MESH:D008113 Liver Neoplasms Tamoxifen 24.0516684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 24.0516984957
MESH:D008113 Liver Neoplasms Urethane 24.0516391232 17559639 17093202
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 25.613712494 598648 6587162 1399818
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 25.618603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 25.6120377131
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 25.6115583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 25.6116842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 25.611399818 2563599 17172636 18308698 6150874
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 25.6112151625
MESH:D008133 Long QT Syndrome arsenic trioxide 7.9215213294
MESH:D008133 Long QT Syndrome olanzapine 7.9220210726
MESH:D008171 Lung Diseases 2-chloroethyl ethyl sulfide 4.4416252256 18675330 12815614
MESH:D008175 Lung Neoplasms Aflatoxin B1 14.6814755239
MESH:D008175 Lung Neoplasms arsenic trioxide 14.6811798837 19825857
MESH:D008175 Lung Neoplasms Azacitidine 14.6821224363
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 14.6818569708 20135361 18816296 6695378 20064080 17053015 20869020 18520028 20464547
MESH:D008175 Lung Neoplasms Doxorubicin 14.6817418594 6189445
MESH:D008175 Lung Neoplasms N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide 14.6821224363
MESH:D008175 Lung Neoplasms Tamoxifen 14.6818625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 14.6819555203 11884234
MESH:D008175 Lung Neoplasms Urethane 14.6816926031 15902970 10530776 11544531 17195641 12957351 16204055 16391232 17093202 12466968 12117781 16289808 15166089 6695378 11992545 11893704 15136453 10822126 11807781 11497255 17255336 11246140 12765245 7750092 11323394 16337739 11062179 10779650 10997738 14587096 16788158 11552296 11074608 11307925 16007126
MESH:D008223 Lymphoma Cyclophosphamide 16.3312854902
MESH:D008223 Lymphoma decitabine 16.3319470736
MESH:D008223 Lymphoma Doxorubicin 16.3316098063
MESH:D008223 Lymphoma Etoposide 16.3312854902 12556972
MESH:D016393 Lymphoma, B-Cell Cyclophosphamide 9.5316675587
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 9.5314737004
MESH:D008228 Lymphoma, Non-Hodgkin Cyclophosphamide 8.2411911406
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 8.2417654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.2915621674
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.4819428831
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 8.9615458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 8.9611807958 17203775 16891317 11408345
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 8.9616827153 14580682 19196722 11731420 19196723
MESH:D020149 Manganese Poisoning Estradiol 11.7019453300
MESH:D020149 Manganese Poisoning Tamoxifen 11.7019453300
MESH:D008545 Melanoma decitabine 4.8617785578 16505122
MESH:D008545 Melanoma Doxorubicin 4.8616827129
MESH:D008545 Melanoma Tamoxifen 4.8619393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.9015990972
MESH:D008546 Melanoma, Experimental Cyclophosphamide 4.5316388313
MESH:D008569 Memory Disorders Ethanol 3.9215451040 18411066
MESH:D001523 Mental Disorders Clozapine 7.6716856516
MESH:D001523 Mental Disorders olanzapine 7.6716856516
MESH:D008654 Mesothelioma Doxorubicin 2.9517638057
MESH:D008659 Metabolic Diseases olanzapine 5.1419142110
MESH:D024821 Metabolic Syndrome X Clozapine 4.1819142101
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.2515792986
MESH:D009006 Monosomy Azacitidine 5.8019299654
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 2.9816381670
MESH:D052016 Mucositis Doxorubicin 4.5117415656
MESH:D009101 Multiple Myeloma arsenic trioxide 11.1119549372 14977855 11468182 19417148 15949261
MESH:D009101 Multiple Myeloma Azacitidine 11.1118443271 19549372
MESH:D009101 Multiple Myeloma decitabine 11.1118172295
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.3918349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 11.5416882451 16105982
MESH:D009190 Myelodysplastic Syndromes Azacitidine 11.5417596541 17611569 19805378 18720364
MESH:D009190 Myelodysplastic Syndromes decitabine 11.5416882708 19010910 19157545 18608210
MESH:D009203 Myocardial Infarction Cocaine 5.9918072171
MESH:D009203 Myocardial Infarction Doxorubicin 5.9919429709 15857846
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.8012213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.0716810080
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.2017484760
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.6916624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 8.853581430
MESH:D009362 Neoplasm Metastasis Doxorubicin 8.8518259882
MESH:D009362 Neoplasm Metastasis Tamoxifen 8.8519393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4219410462
MESH:D009369 Neoplasms Benzo(a)pyrene 10.8111141357
MESH:D009369 Neoplasms Cyclophosphamide 10.8118854779
MESH:D009369 Neoplasms decitabine 10.8119116145 17925555 19470736
MESH:D009369 Neoplasms Urethane 10.8115625555
MESH:D009374 Neoplasms, Experimental Urethane 4.4115582191
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.7219189210 19196722 19200415
MESH:D009389 Neovascularization, Pathologic Estradiol 3.4517289903
MESH:D009397 Nephrocalcinosis Furosemide 5.5915086907
MESH:D009401 Nephrosis Doxorubicin 4.4916899518 16636307
MESH:D009404 Nephrotic Syndrome Doxorubicin 3.7716889571 15640375
MESH:D009421 Nervous System Malformations Estradiol 8.5816427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 8.5814600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 6.656679447
MESH:D009436 Neural Tube Defects arsenic trioxide 6.6510525206
MESH:D009447 Neuroblastoma Cyclophosphamide 6.738761367 16115947 15176712
MESH:D009447 Neuroblastoma Doxorubicin 6.7315555623
MESH:D017599 Neuroectodermal Tumors Cyclophosphamide 4.6112837982 8761367
MESH:D009503 Neutropenia Cyclophosphamide 4.078291058
MESH:D052556 Niemann-Pick Disease, Type C Cholesterol 5.439802331 20557099
MESH:D053206 Nocturnal Enuresis Furosemide 5.5917945291
MESH:D009765 Obesity 2-chloroethyl ethyl sulfide 7.5016289378
MESH:D009765 Obesity Clozapine 7.5019142110 18515891
MESH:D009765 Obesity olanzapine 7.5018515891
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.186482804 4026338
MESH:D009845 Oligospermia Cyclophosphamide 4.4316517039
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.733988306
MESH:D010018 Osteomalacia Phenobarbital 4.0817016548
MESH:C536063 Osteoporosis-pseudoglioma syndrome pamidronate 6.7418825883
MESH:D012516 Osteosarcoma Doxorubicin 3.8915930896
MESH:D010051 Ovarian Neoplasms arsenic trioxide 10.6019769630 16624393 12452020
MESH:D010051 Ovarian Neoplasms decitabine 10.6019259094 19331143
MESH:D010051 Ovarian Neoplasms Estradiol 10.6019401270
MESH:D010051 Ovarian Neoplasms Urethane 10.6016391232
MESH:D010146 Pain Cyclophosphamide 3.4112161096 18093676
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 19.1715580305
MESH:D010190 Pancreatic Neoplasms Cyclophosphamide 19.1711332152
MESH:D010190 Pancreatic Neoplasms decitabine 19.1719294695
MESH:D010190 Pancreatic Neoplasms Ethanol 19.1712384795
MESH:D010190 Pancreatic Neoplasms Etoposide 19.1719003803
MESH:D010190 Pancreatic Neoplasms Phenobarbital 19.1716965848
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.217296757
MESH:D010235 Paraganglioma arsenic trioxide 3.9019927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.9612520081
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.196228378
MESH:D003557 Phyllodes Tumor Doxorubicin 4.8717983394
MESH:D010911 Pituitary Neoplasms Urethane 5.1416391232
MESH:D010997 Pleural Neoplasms Doxorubicin 4.8717638057
MESH:D011141 Polyuria Furosemide 5.3717945291
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.2918163543
MESH:D011230 Precancerous Conditions Phenobarbital 3.392563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Cyclophosphamide 3.6521297632
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 2.9111399792 11896295 11222880 11118676
MESH:D055728 Primary Myelofibrosis decitabine 4.4517616702
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.6320887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.4319131511
MESH:D011471 Prostatic Neoplasms Azacitidine 3.4318324645
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.4317292933
MESH:D011471 Prostatic Neoplasms Cyclophosphamide 3.4317136230
MESH:D011471 Prostatic Neoplasms Doxorubicin 3.4318437689 15897917 16888761 16868541 15749863 16729912
MESH:D011471 Prostatic Neoplasms Estradiol 3.4316740699
MESH:D011471 Prostatic Neoplasms Etoposide 3.4317172428
MESH:D011471 Prostatic Neoplasms N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide 3.4318798265
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.4318760546
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.4315067354
MESH:D019310 Pseudolymphoma Phenobarbital 4.2112752131
MESH:D011595 Psychomotor Agitation olanzapine 5.3118685284
MESH:D011618 Psychotic Disorders Clozapine 8.7115331141
MESH:D011618 Psychotic Disorders Cocaine 8.7116134406
MESH:D011658 Pulmonary Fibrosis Cyclophosphamide 3.1816636934
MESH:D051437 Renal Insufficiency Doxorubicin 3.9517922066
MESH:D015427 Reperfusion Injury Furosemide 3.7716526316
MESH:D012128 Respiratory Distress Syndrome, Adult 2-chloroethyl ethyl sulfide 9.0712210543 18257742 16292752
MESH:D012128 Respiratory Distress Syndrome, Adult Furosemide 9.0712394941 16096441 15912074
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.5718990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.173692021
MESH:D012208 Rhabdomyosarcoma decitabine 4.1419155313
MESH:D012509 Sarcoma Doxorubicin 3.7515675481 17203757 18313854 16767912 17710206 15625365
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 15.7816646077
MESH:D012512 Sarcoma, Ewing's Doxorubicin 15.7814601052 16326096
MESH:D012512 Sarcoma, Ewing's Etoposide 15.7814601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.5117846226
MESH:D012559 Schizophrenia Clozapine 4.1818855531 20521326 16141801 17726453 20107430 11763009 20580759 17123785 18806925 19369910 17667964 20452607 20521320 20168265 11151749
MESH:D012559 Schizophrenia olanzapine 4.1820107430 17726453 20521326
MESH:D012595 Scleroderma, Systemic Cyclophosphamide 4.5616636934
MESH:D012640 Seizures Cocaine 9.0110454489
MESH:D012640 Seizures Ethanol 9.019754883
MESH:D012640 Seizures Phenobarbital 9.013137016 11442880 16876388 4039156
MESH:D003294 Seizures, Febrile Phenobarbital 4.546407741
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 12.5210029692 19755658
MESH:D012878 Skin Neoplasms Doxorubicin 12.5215692506
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 12.5216192470
MESH:D012878 Skin Neoplasms Urethane 12.5211807781
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.2915625365 17203757 16767912
MESH:D013088 Spermatocele Tamoxifen 4.0116709447
OMIM:102530 SPERMATOGENIC FAILURE 6 Cyclophosphamide 5.2316517039
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.7619457130
MESH:D013274 Stomach Neoplasms arsenic trioxide 6.0917007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 6.0920155912 2093021
MESH:D013274 Stomach Neoplasms decitabine 6.0919037991
MESH:D013274 Stomach Neoplasms Ethanol 6.0918456281
MESH:D013274 Stomach Neoplasms Furosemide 6.0917052386
MESH:D013276 Stomach Ulcer Ethanol 3.2911906479 9562338 17918041 9211565 17189318 16755016
MESH:D013375 Substance Withdrawal Syndrome Ethanol 4.019754883
MESH:D015173 Supratentorial Neoplasms Cyclophosphamide 4.7812837982
MESH:D017180 Tachycardia, Ventricular olanzapine 5.0720210726
MESH:D013733 Testicular Diseases pyrazole 4.546499806
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.6212697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 20.251399818 3712494 7505956 6582329 6587162
MESH:D013964 Thyroid Neoplasms arsenic trioxide 20.2519014326
MESH:D013964 Thyroid Neoplasms decitabine 20.2517967635
MESH:D013964 Thyroid Neoplasms Doxorubicin 20.2516010429 17909728
MESH:D013964 Thyroid Neoplasms Phenobarbital 20.251399818
MESH:D013978 Tibial Fractures Estradiol 4.4019048282
MESH:D016171 Torsades de Pointes arsenic trioxide 3.6815213294
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 22.438074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 22.4311780464 12845720 12973940 20435036
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 22.4317053015
MESH:D001749 Urinary Bladder Neoplasms Cyclophosphamide 22.4314692829
MESH:D001749 Urinary Bladder Neoplasms decitabine 22.4319087683 17616700
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 22.4317653716
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 22.4317572228 16712894 8653321
MESH:D014604 Uveal Neoplasms decitabine 4.6317785578
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.3112125929
MESH:D019043 Vascular Neoplasms Urethane 5.6310620525
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 3.9516364871 17638931 17334414 17678736
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.9615886252
MESH:D015430 Weight Gain Clozapine 9.5716141801 20107430 20564506 20521320 16402076 17502770
MESH:D015430 Weight Gain olanzapine 9.5717933447 19434072 20107430
MESH:D015431 Weight Loss Clozapine 4.8017933447
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA25354
  • No data
    No data
    Releated drug ID Related drug Name
    PA448691busulfan
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018