AutismKB 2.0

Annotation Detail for SDC4


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SDC4 ( MGC22217,SYND4 )
Gene Full Name: syndecan 4
Band: 20q13.12
Quick LinksEntrez ID:6385; OMIM: 600017; Uniprot ID:SDC4_HUMAN; ENSEMBL ID: ENSG00000124145; HGNC ID: 10661
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05144Malaria
hsa04514Cell adhesion molecules (CAMs)
hsa04512ECM-receptor interaction
No data
Pathway IDPathway Name
200111Proteogylcan syndecan-mediated signaling events
200115Syndecan-4-mediated signaling events
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1832Congenital abnormality
1944Breast cancer
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in increased expression of SDC4 mRNAincreases expression 16788091
D000082 Acetaminophen Acetaminophen affects the expression of SDC4 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of SDC4 mRNAaffects expression 16483693
D001104 Arbutin Arbutin results in decreased expression of SDC4 mRNAdecreases expression 17103032
C006632 arsenic trioxide arsenic trioxide results in decreased expression of SDC4 mRNAdecreases expression 15761015
D001280 Atrazine Atrazine results in increased expression of SDC4 mRNAincreases expression 18585445
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of SDC4 mRNAincreases expression 19150397
C002791 bismuth tripotassium dicitrate bismuth tripotassium dicitrate results in increased expression of SDC4 mRNAincreases expression 15912405
C055494 caffeic acid phenethyl ester [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of SDC4 mRNAaffects cotreatment|increases expression 20360939
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of SDC4 mRNAaffects expression 17484886
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of SDC4 mRNAdecreases expression 17056239
D003345 Corticosterone Corticosterone results in increased expression of SDC4 mRNAincreases expression 15755911
D016572 Cyclosporine Cyclosporine results in increased expression of SDC4 mRNAincreases expression 20106945
C014347 decitabine decitabine results in increased expression of SDC4 mRNAincreases expression 19151715
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of SDC4 mRNAaffects cotreatment|increases expression 20360939
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of SDC4 mRNAdecreases expression 17108234
D015525 Fatty Acids, Omega-3 Fatty Acids, Omega-3 results in increased expression of SDC4 mRNAincreases expression 16823509
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased expression of SDC4increases expression 18687144
C051890 irinotecan irinotecan metabolite results in increased expression of SDC4 mRNAincreases expression 15956246
C051890 irinotecan irinotecan results in increased expression of SDC4 mRNAincreases expression 15956246
C011890 kojic acid kojic acid results in decreased expression of SDC4 mRNAdecreases expression 16595896
D001556 Lindane Lindane results in increased expression of SDC4 mRNAincreases expression 17785943
D005996 Nitroglycerin Nitroglycerin results in decreased expression of SDC4 mRNAdecreases expression 12102619
C042763 olive oil olive oil analog affects the expression of SDC4 mRNAaffects expression 17349074
D043371 Fatty Acids, Omega-6 Fatty Acids, Omega-6 results in increased expression of SDC4 mRNAincreases expression 16823509
C023036 perfluorooctanoic acid perfluorooctanoic acid results in decreased expression of SDC4 mRNAdecreases expression 16221955
D010672 Phenytoin Phenytoin results in decreased expression of SDC4 mRNAdecreases expression 15136057
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of SDC4 mRNAaffects binding|decreases expression|increases activity 19710929
C006253 pirinixic acid pirinixic acid results in increased expression of SDC4 mRNAincreases expression 18445702
C009250 sevoflurane sevoflurane affects the expression of SDC4 mRNAaffects expression 15967596
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenytoin 4.263425630 6195326 8986270 10563481 9677735 9118846
MESH:D000138 Acidosis Ammonium Chloride 3.3318287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.7117505938
MESH:D055371 Acute Lung Injury pirinixic acid 2.9118653653
MESH:D000230 Adenocarcinoma arsenic trioxide 4.0911798837 19825857
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.0914692618
MESH:D000236 Adenoma Diethylnitrosamine 2.726695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 9.3319052882 16434500 17162532 19061943 17620307 18056438
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.3316434500
MESH:D000382 Agricultural Workers' Diseases Atrazine 8.3811874814
MESH:D000382 Agricultural Workers' Diseases Lindane 8.3812661182
MESH:D000799 Angioedema Acetaminophen 3.6110982225
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.2411256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.5315885639
MESH:D050197 Atherosclerosis olive oil 7.0916216721
MESH:D050197 Atherosclerosis Phenytoin 7.0915136057
MESH:D001289 Attention Deficit Disorder with Hyperactivity Fatty Acids, Omega-3 8.7618448859
MESH:D001289 Attention Deficit Disorder with Hyperactivity Fatty Acids, Omega-6 8.7618448859
MESH:D001321 Autistic Disorder Acetaminophen 2.3918445737
MESH:D001321 Autistic Disorder Fatty Acids, Omega-3 2.3916920077
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 8.3216206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.3219483382
MESH:D001943 Breast Neoplasms decitabine 2.0818320071 19208741
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.0817474063
MESH:D001943 Breast Neoplasms Lindane 2.0814688026
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.1211589617
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.563786805 16050911 10355542 16227642 16097048 15700767 18705752 15673190 16124888 16192424 16011737 15721981
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 6.243084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 6.2415553829 15073043 16217749 11135700 14691202
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 6.2418788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 6.2419394651 20524982 3581430 18393292 18691550 19539802 20214788 20514400 18665156 19519916 18494052 16502159 16698587 18785209 20101231 16328049 18056438 18506893 16935385 19208518 17162532 16779866 19335982 17173139 19919837 19171122 17428255 21159647 16681979 17761372 20432363 20007298 16830150 19701751 10737359 18788625 16569478 3084413 10672840 17978847 19107877 16807293 19383236 19822196 16540662 20727157 17055752 16288022 20084675 16878318 19418558 11831363 20935162 18210153 20512989 17138121 18978308 19052882 18971187
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.6419014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.9212490120
MESH:D002294 Carcinoma, Squamous Cell decitabine 2.5319215824
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 7.4616936243
MESH:D002318 Cardiovascular Diseases olive oil 7.4616216721
MESH:D002386 Cataract Acetaminophen 2.4510977129
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 10.2520889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 10.2512371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 10.257505956 17174075 21159647 2727394
MESH:D002493 Central Nervous System Diseases Phenytoin 5.074080065
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.4919052882
MESH:D002779 Cholestasis Cyclosporine 12.3819486331
MESH:D002779 Cholestasis Ethinyl Estradiol 12.3816919318 11677210 16105132 15861022 17681005 17333356 17110522
MESH:D002779 Cholestasis pirinixic acid 12.3819176532
OMIM:601042 CHOREOATHETOSIS/SPASTICITY, EPISODIC Phenytoin 5.6411748493
MESH:D002971 Cleft Lip Phenytoin 4.042227380
MESH:D002972 Cleft Palate Phenytoin 3.651687470 3877104 6856622 10789828 2227380 6862529
MESH:D003103 Coloboma Phenytoin 4.959212184
MESH:D003110 Colonic Neoplasms decitabine 3.8517616700
MESH:D003110 Colonic Neoplasms irinotecan 3.8517725105 17287894
MESH:D015179 Colorectal Neoplasms arsenic trioxide 3.4020501625
MESH:D015179 Colorectal Neoplasms decitabine 3.4018981723
MESH:D015179 Colorectal Neoplasms irinotecan 3.4018259882 16391804 17159606 16303861 18509181 17454858 15273666
MESH:D000013 Congenital Abnormalities Phenytoin 4.5110627286
MESH:D023903 Coronary Restenosis arsenic trioxide 3.9712609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.0010525206
MESH:D019465 Craniofacial Abnormalities Phenytoin 3.0019952982 9212184 8986270
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.8815213294
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3218249437
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 2.1420387270
OMIM:607208 DRAVET SYNDROME Phenytoin 5.1611748493
MESH:D003875 Drug Eruptions Phenytoin 5.2715024534
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 5.7916081117 14986274 18071297 11834606 14725611 11743745 19739265 12540782 19085960 16485898 12153990 12958197 11287661 10663392 19416960 19370779 11461765 17562736 15968718 12594235 10915739 15619225 17906064 19923254 16781746 17522070 12705907 16393943 16177239 11739529 18713872 12392966 19420014 11529661 11421492 16109766 16227642 14550746 19164858 10774834 2444490
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 5.7915968718 2869522 7440962 3732212 19085960 21278145 17522070 7179309 6623471 15027814 11566570 3786805 16227642 10092053 16177239 7120509 15998439 10915739 9327722 19336974 4309450 6884620
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 5.7919107877
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.8719426721
MESH:D004487 Edema perfluorooctanoic acid 6.3112083418 17259670
MESH:D004487 Edema pirinixic acid 6.3112083418
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.6412538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Phenytoin 8.6417654737
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.8819294695
MESH:D004816 Epidermal Necrolysis, Toxic Phenytoin 4.9820235791
MESH:D004820 Epidermolysis Bullosa Phenytoin 6.001399206 6251365
MESH:D004828 Epilepsies, Partial Phenytoin 4.6911558140 17116037
MESH:D004827 Epilepsy Phenytoin 3.82821787 11434505 20417680
MESH:D017029 Epilepsy, Complex Partial Phenytoin 5.077750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenytoin 4.843659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.8916302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.2620426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.2612903497
MESH:D005234 Fatty Liver arsenic trioxide 28.0415073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 28.0416045604 12631006 61145 15959796 16239168 12795759 17595544 19224547
MESH:D005234 Fatty Liver Cyclosporine 28.0419224547
MESH:D005234 Fatty Liver Diethylnitrosamine 28.0420387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 28.0415345470
MESH:D005234 Fatty Liver pirinixic acid 28.0419236843 20131406
MESH:D005313 Fetal Death Phenytoin 4.8710627286
MESH:D005355 Fibrosis Carbon Tetrachloride 7.9218705752
MESH:D005355 Fibrosis Cyclosporine 7.9212168785 12639820
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.0416904648
MESH:D005756 Gastritis Acetaminophen 3.4416983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 12.148708960
MESH:D005885 Gingival Hyperplasia Phenytoin 12.149029455
MESH:D019214 Gingival Overgrowth Phenytoin 6.0016390469 14659971
MESH:D006261 Headache Nitroglycerin 4.9611284996 11554966
MESH:D006258 Head and Neck Neoplasms decitabine 3.3419215824
MESH:D006333 Heart Failure pirinixic acid 2.4020558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.1915720958
MESH:D006505 Hepatitis Carbon Tetrachloride 3.3819900420 19110552
MESH:D006529 Hepatomegaly perfluorooctanoic acid 7.963609246
MESH:D006529 Hepatomegaly pirinixic acid 7.9619176532 19772884 16221962 18467677
MESH:D006930 Hyperalgesia Acetaminophen 7.2716870215
MESH:D006930 Hyperalgesia perfluorooctanoic acid 7.2712083418
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.3016899240
MESH:D006943 Hyperglycemia pirinixic acid 2.9920558911
MESH:D020138 Hyperhomocysteinemia Phenytoin 4.4810459572
MESH:D006973 Hypertension Cyclosporine 2.0110903974
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.8615338365
MESH:D007021 Hypospadias Ethinyl Estradiol 3.5816569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.2512013081
MESH:D007248 Infertility, Male Atrazine 10.4512948887
MESH:D007248 Infertility, Male decitabine 10.4517581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 10.4517937319
MESH:D007249 Inflammation Diethylnitrosamine 7.9618785209
MESH:D007249 Inflammation Fatty Acids, Omega-3 7.9617296493
MESH:D007249 Inflammation perfluorooctanoic acid 7.9612083418
MESH:D007333 Insulin Resistance pirinixic acid 2.4916306350
MESH:D007414 Intestinal Neoplasms caffeic acid phenethyl ester 4.3910783313
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.2115604871
MESH:D007674 Kidney Diseases Acetaminophen 9.3512587719 15629191
MESH:D007674 Kidney Diseases caffeic acid phenethyl ester 9.3515369732
MESH:D007674 Kidney Diseases Cyclosporine 9.3518776723 10903974 8314463
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 4.0716518626
MESH:D007680 Kidney Neoplasms Cyclosporine 2.5512371664
MESH:D007859 Learning Disorders sevoflurane 4.5519212262
MESH:D007938 Leukemia arsenic trioxide 6.0815070760
MESH:D007938 Leukemia decitabine 6.0819235587 18980019
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.5917077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.0816972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.2614633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 8.9019077051
MESH:D007951 Leukemia, Myeloid decitabine 8.9018454857 19117987 17236224
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.8520471514 17050201 16968895 19850784 16467208
MESH:D015470 Leukemia, Myeloid, Acute decitabine 3.8519010910 18460780 19387464 17679729 18206229 18704418
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.2318055864
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 7.4517649720 12679006 15622746 16331271 9834237 11161223 17712046 15336539 19075265 19035177 16823087 12018890 15213294 19642359 16891316 17217047 16330433 19225113 11468182 16966277 17869043 17107899 12712474 16112521 15748426
MESH:D015473 Leukemia, Promyelocytic, Acute caffeic acid phenethyl ester 7.4516766008
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.1316882451
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 5.008812269
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 6.1911408273 16943688 17334410 16239168 21278145 16221502 17174718 11903743 17157831
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.1918522880 19638242 20032147 18665156 18407596
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 2.2512632512 15052691 18279442 18420326 18418968 18054572 12667390 14748882 12632514 15818738 15673190 12389079 17805973 18472332 17640975 17698563 17565644 14512876 12741479 17481882 18156304 16097048 15730626 16011737 15057751 15925388 18429990 16638106 15123356 17944888 15338365 12666154 17631135 18006644 18205269 14620537 12958196 17823541 16248980 12609069 18210741 18317297 15876570 16136751 18339082 18472094 16192424 18263696 17525996 18251166 12586293 17714472 15996030 17708605 20821823 14716833 17766677 12546737 16027843 16015684 17721639 17869086 18187930 15370692 15893842 14716496 12445421 18395095 10355542 12649538 15362042 17976157 14724832 12445418 16116963 17922224 15650968 17900296 11481614 18395914 13678700 18376398 18705752 15959796 18481824 18277467 18166357 15931870 16033810 12898905 17557913 18412020 17761835
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 2.2515474484
MESH:D008107 Liver Diseases Acetaminophen 11.9016611625 11587558 12969438 19460945 16610002 12587719 19014921 19784758
MESH:D008107 Liver Diseases Carbon Tetrachloride 11.9016246199 15830285 17285989 15720792 16964402
MESH:D008107 Liver Diseases Diethylnitrosamine 11.9017034775
MESH:D008107 Liver Diseases Lindane 11.901715830
MESH:D008107 Liver Diseases Phenytoin 11.9014986274
MESH:D017093 Liver Failure Carbon Tetrachloride 3.9415123358
MESH:D017114 Liver Failure, Acute Acetaminophen 8.7517185352 16871587
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 8.7516899240 14706259
MESH:D008113 Liver Neoplasms arsenic trioxide 13.3214682389
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 13.3219294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 13.3219850985 19638242 20492335 21278145 19255062 19426721 2862719 20452335 19256749 21047994 19090486 12112319 19642983 12771043 21071580 20101389 9163691 20405173 20118626 19073162 2422723 19427195 21167192 19690152 19996281 19812893 19551842 15175105 18978307 19294768 20501860 19254457 18648771 18644402 15885732 19499222 18977376 20137499 10737359 16942905 20583210 18754104 19833225 20434301
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 13.3218709148 14757943
MESH:D008113 Liver Neoplasms pirinixic acid 13.3215890375 16377806 20007298
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 13.0120377131
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 13.0112014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 13.0117174075 18079962 17854601 18253720 16842330 19009564 18282651 3124819 2563599 16267830 21159647 19126423 18308698 19539802 17942915 18775883 9362446 18544905 18093689 18164116 19519916 19004024
MESH:D008114 Liver Neoplasms, Experimental kojic acid 13.0118544905
MESH:D008133 Long QT Syndrome arsenic trioxide 3.1815213294
MESH:D008175 Lung Neoplasms arsenic trioxide 2.4211798837 19825857
MESH:D008175 Lung Neoplasms Diethylnitrosamine 2.4220512841 6695378 21163286 20970405
MESH:D008223 Lymphoma decitabine 3.2619470736
MESH:D008325 Mammary Neoplasms, Experimental Corticosterone 3.4912807724
MESH:D008545 Melanoma decitabine 2.2217785578 16505122
MESH:D008546 Melanoma, Experimental Acetaminophen 3.3419513568
MESH:D008569 Memory Disorders sevoflurane 4.5319212262
MESH:D008607 Mental Retardation Phenytoin 3.599212184
MESH:D008654 Mesothelioma Atrazine 3.441916698
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.5616801185
MESH:D008708 Methemoglobinemia Nitroglycerin 4.523537620
MESH:D020326 Migraine without Aura Nitroglycerin 4.9114659530
MESH:D052016 Mucositis irinotecan 4.7817159606
MESH:D009101 Multiple Myeloma arsenic trioxide 6.8419417148 19549372 15949261 14977855 11468182
MESH:D009101 Multiple Myeloma decitabine 6.8418172295
MESH:D009135 Muscular Diseases pirinixic acid 3.2816239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.4418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 7.0716882451 16105982
MESH:D009190 Myelodysplastic Syndromes decitabine 7.0719157545 18608210 19010910 16882708
MESH:D009203 Myocardial Infarction Nitroglycerin 5.7014729435
MESH:D009203 Myocardial Infarction pirinixic acid 5.7019151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.7716411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenytoin 5.2917484760
MESH:D009224 Myotonia Congenita Phenytoin 5.181896199
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.7416624393
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.653581430 9029167
MESH:D009362 Neoplasm Metastasis irinotecan 5.6518259882
MESH:D009369 Neoplasms decitabine 7.7419116145 17925555 19470736
MESH:D009369 Neoplasms Lindane 7.7416818664 12807735
MESH:D009369 Neoplasms pirinixic acid 7.7417405874
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.2117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.0919348381 18481113
MESH:D009436 Neural Tube Defects arsenic trioxide 7.2110525206
MESH:D009436 Neural Tube Defects Phenytoin 7.219118846
MESH:D009447 Neuroblastoma irinotecan 3.368761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.5718514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.5720387270
MESH:D017599 Neuroectodermal Tumors irinotecan 4.508761367
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.8920387270
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 4.739802331
MESH:D009765 Obesity pirinixic acid 1.7620558911
MESH:D010018 Osteomalacia Phenytoin 5.1817016548
MESH:D010051 Ovarian Neoplasms arsenic trioxide 4.7419769630 16624393 12452020
MESH:D010051 Ovarian Neoplasms decitabine 4.7419331143 19259094
MESH:D010146 Pain Acetaminophen 6.3816870215
MESH:D010146 Pain Phenytoin 6.3815215642
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 8.1715580305
MESH:D010190 Pancreatic Neoplasms decitabine 8.1719294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 8.1716540662
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.4711578682
MESH:D010212 Papilloma Hydrogen Peroxide 3.8612065085
MESH:D010235 Paraganglioma arsenic trioxide 3.9519927285
MESH:D010300 Parkinson Disease Atrazine 3.1917218051
MESH:D017689 Polydactyly Phenytoin 4.859212184
MESH:D011230 Precancerous Conditions Cyclosporine 8.3112371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.312563599
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 4.1717132714
MESH:D055728 Primary Myelofibrosis decitabine 4.5017616702
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.7019131511
MESH:D011471 Prostatic Neoplasms Lindane 3.7012661182 14688026
MESH:D011537 Pruritus Ethinyl Estradiol 3.0915861022 16919318
MESH:D019310 Pseudolymphoma Phenytoin 5.318603615 1419762 12752131
MESH:D011565 Psoriasis Cyclosporine 2.1516882103
MESH:D015427 Reperfusion Injury pirinixic acid 2.2819058328
MESH:D012135 Respiratory Sounds Atrazine 4.2911874814
MESH:D012208 Rhabdomyosarcoma decitabine 4.1919155313
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.7416646077
MESH:D012640 Seizures Lindane 6.207539098 12842176 15475178
MESH:D012640 Seizures Phenytoin 6.2011044598 3691417 10029267 16876388 3137016 19919933 15946322 9844417
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 2.9712065085
MESH:D013088 Spermatocele Ethinyl Estradiol 3.7116709447
MESH:D013262 Stevens-Johnson Syndrome Phenytoin 4.9320235791
MESH:D013274 Stomach Neoplasms arsenic trioxide 4.5617007042
MESH:D013274 Stomach Neoplasms decitabine 4.5619037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 4.5618456281
MESH:D013274 Stomach Neoplasms irinotecan 4.5615723263
MESH:D013276 Stomach Ulcer olive oil 4.3212498302 16252198
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.4111994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.9615669648
MESH:D013964 Thyroid Neoplasms arsenic trioxide 11.0219014326
MESH:D013964 Thyroid Neoplasms decitabine 11.0217967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 11.027505956
MESH:D016171 Torsades de Pointes arsenic trioxide 3.7315213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 4.9412973940 12845720 11780464 20435036
MESH:D001749 Urinary Bladder Neoplasms decitabine 4.9417616700 19087683
MESH:D014581 Urticaria Acetaminophen 2.7710982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.0814692618
MESH:D014604 Uveal Neoplasms decitabine 4.6817785578
MESH:D014605 Uveitis Cyclosporine 3.751336536
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.3315869587 14671159
MESH:D014985 Xerophthalmia Cyclosporine 4.2117120751
Pathway ID Pathway Name
KEGG:04514 Cell adhesion molecules (CAMs)
KEGG:04512 ECM-receptor interaction
KEGG:05144 Malaria
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved