AutismKB 2.0

Annotation Detail for CXCL12


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Basic Information Top
Gene Symbol:CXCL12 ( IRH,PBSF,SCYB12,SDF1,SDF1A,SDF1B,TLSF,TPAR1 )
Gene Full Name: chemokine (C-X-C motif) ligand 12
Band: 10q11.21
Quick LinksEntrez ID:6387; OMIM: 600835; Uniprot ID:SDF1_HUMAN; ENSEMBL ID: ENSG00000107562; HGNC ID: 10672
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04672Intestinal immune network for IgA production
hsa04670Leukocyte transendothelial migration
hsa04360Axon guidance
hsa04062Chemokine signaling pathway
hsa04060Cytokine-cytokine receptor interaction
Pathway IDPathway Name
Signaling by GPCR
Pathway IDPathway Name
200083CXCR4-mediated signaling events
200172HIF-1-alpha transcription factor network
200115Syndecan-4-mediated signaling events
Pathway IDPathway Name
P00008Axon guidance mediated by Slit/Robo
Pathway IDPathway Name
500406Chemokine receptors bind chemokines
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1739Oral cancer
1767Immunologic deficiency syndrome
1781Rheumatoid arthritis
1809HIV infection
1869Behcet syndrome
1877Multiple sclerosis
1904Diabetes mellitus
1918Atherosclerosis
1934Cancer
2025Polyarthritis
2011Leukoencephalopathy
2081Pulmonary fibrosis
2146Lupus erythematosus
2177Wiskott-Aldrich syndrome
2231Arthritis
Desease Name
HEMATOLOGICAL
leukemia, myeloid
Atherosclerosis
increased perinatal immunodeficiency virus type 1 transmission
CARDIOVASCULAR
diabetes, type 1
myocardial infarction (early onset)
CANCER
Coronary Disease
IMMUNE
HIV
INFECTION
hematopoietic progenitor cells, mobilization of
Desease Name
Coronary heart disease
Myocardial infarction (early onset)
Desease Name
AIDS, resistance to
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C028474 1,4-bis(2-(3,5-dichloropyridyloxy))benzene 1,4-bis(2-(3,5-dichloropyridyloxy))benzene affects the expression of CXCL12 mRNAaffects expression 18281256
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of CXCL12 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of CXCL12 mRNAaffects expression 21346803
C076996 27-hydroxycholesterol 27-hydroxycholesterol results in increased expression of CXCL12 mRNAincreases expression 17872378
C076996 27-hydroxycholesterol fulvestrant inhibits the reaction [27-hydroxycholesterol results in increased expression of CXCL12 mRNA]decreases reaction|increases expression 17872378
D000082 Acetaminophen Acetaminophen affects the expression of CXCL12 mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen results in decreased expression of CXCL12 mRNAdecreases expression 17202762
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CXCL12 mRNAaffects expression 16483693
C004984 apocarotenal apocarotenal results in increased expression of CXCL12 mRNAincreases expression 17034753
D001374 Azacitidine Azacitidine results in decreased methylation of CXCL12 promoterdecreases methylation 19748759
D001374 Azacitidine Azacitidine results in increased expression of CXCL12 mRNAincreases expression 19748759
D001374 Azacitidine Azacitidine results in increased expression of CXCL12 proteinincreases expression 19748759
D001554 Benzene Benzene results in increased expression of CXCL12 mRNAincreases expression 15120971
15122651
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of CXCL12 mRNAaffects expression 20382639
D019207 beta Carotene beta Carotene results in increased expression of CXCL12 mRNAincreases expression 17034753
D002118 Calcium CXCL12 protein results in increased uptake of Calciumincreases uptake 10984371
11872090
D002118 Calcium resveratrol inhibits the reaction [CXCL12 protein affects the localization of Calcium]affects localization|decreases reaction 16212921
C020243 calcium phosphate calcium phosphate results in increased expression of CXCL12 proteinincreases expression 14600836
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of CXCL12 mRNAdecreases expression 17484886
D002251 Carbon Tetrachloride [2-Acetylaminofluorene co-treated with Carbon Tetrachloride] results in increased expression of CXCL12 proteinaffects cotreatment|increases expression 12626097
C019304 ciprofibrate ciprofibrate results in decreased expression of CXCL12 mRNAdecreases expression 12771043
D002995 Clofibric Acid Clofibric Acid affects the expression of CXCL12 mRNAaffects expression 17602206
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CXCL12 mRNAaffects cotreatment|affects expression 17602206
C030123 coumarin coumarin results in decreased expression of CXCL12 mRNAdecreases expression 18480146
D003474 Curcumin Curcumin inhibits the reaction [CXCL12 protein results in increased expression of CXCR4 mRNA]decreases reaction|increases expression 18660423
D003474 Curcumin Curcumin inhibits the reaction [CXCL12 protein results in increased phosphorylation of AKT1 protein]decreases reaction|increases phosphorylation 18660423
D003474 Curcumin Curcumin inhibits the reaction [CXCL12 protein results in increased phosphorylation of NOS3 protein]decreases reaction|increases phosphorylation 18660423
D003520 Cyclophosphamide Cyclophosphamide affects the expression of CXCL12 mRNAaffects expression 12624490
D003520 Cyclophosphamide Cyclophosphamide results in increased expression of CXCL12 mRNAincreases expression 16337237
D016047 Zalcitabine Zalcitabine results in increased expression of CXCL12 mRNAincreases expression 17292584
C014347 decitabine decitabine results in increased expression of CXCL12 mRNAincreases expression 19289100
D003907 Dexamethasone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CXCL12 mRNAaffects cotreatment|decreases expression 16054899
D003907 Dexamethasone [Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CXCL12 mRNA]affects cotreatment|decreases expression|decreases reaction 16054899
D003907 Dexamethasone Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CXCL12 mRNA]affects cotreatment|decreases expression|decreases reaction 16054899
D004041 Dietary Fats Dietary Fats results in increased expression of CXCL12 mRNAincreases expression 18042831
D004052 Diethylnitrosamine Diethylnitrosamine results in decreased expression of CXCL12 mRNAdecreases expression 12771043
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CXCL12 mRNAaffects cotreatment|affects expression 17602206
D004052 Diethylnitrosamine Diethylnitrosamine results in decreased expression of CXCL12 mRNAdecreases expression 19638242
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of CXCL12 mRNAaffects cotreatment|decreases expression 19619570
D004958 Estradiol Estradiol results in increased expression of CXCL12 mRNAincreases expression 17872378
17555868
19619570
15986123
15913882
D004958 Estradiol fulvestrant inhibits the reaction [Estradiol results in increased expression of CXCL12 mRNA]decreases reaction|increases expression 17872378
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of CXCL12 mRNAdecreases expression 17557909
D015073 2-Acetylaminofluorene [2-Acetylaminofluorene co-treated with Carbon Tetrachloride] results in increased expression of CXCL12 proteinaffects cotreatment|increases expression 12626097
D015073 2-Acetylaminofluorene 2-Acetylaminofluorene results in increased expression of CXCL12 mRNAincreases expression 15579440
D015073 2-Acetylaminofluorene 2-Acetylaminofluorene results in increased expression of CXCL12 proteinincreases expression 15579440
D005472 Fluorouracil Fluorouracil affects the expression of CXCL12 mRNAaffects expression 18344199
D005472 Fluorouracil Fluorouracil results in increased expression of CXCL12 mRNAincreases expression 16337237
C070081 fulvestrant fulvestrant inhibits the reaction [27-hydroxycholesterol results in increased expression of CXCL12 mRNA]decreases reaction|increases expression 17872378
C070081 fulvestrant fulvestrant inhibits the reaction [Estradiol results in increased expression of CXCL12 mRNA]decreases reaction|increases expression 17872378
C056933 fumonisin B1 fumonisin B1 results in decreased expression of CXCL12 mRNAdecreases expression 16221962
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased expression of CXCL12 mRNAincreases expression 17997286
D006861 Hydrogen Peroxide Sodium Selenite inhibits the reaction [Hydrogen Peroxide results in increased expression of CXCL12 mRNA]decreases reaction|increases expression 17997286
C051890 irinotecan irinotecan analog results in decreased expression of CXCL12 mRNAdecreases expression 18927307
D015056 1-Methyl-3-isobutylxanthine [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CXCL12 mRNAaffects cotreatment|decreases expression 16054899
D015056 1-Methyl-3-isobutylxanthine [Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CXCL12 mRNA]affects cotreatment|decreases expression|decreases reaction 16054899
D015056 1-Methyl-3-isobutylxanthine Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CXCL12 mRNA]affects cotreatment|decreases expression|decreases reaction 16054899
C088327 JM 3100 JM 3100 inhibits the reaction [CXCL12 protein affects the localization of CXCR4 protein]affects localization|decreases reaction 12220670
C088327 JM 3100 JM 3100 inhibits the reaction [CXCL12 protein results in increased phosphorylation of AKT1 protein]decreases reaction|increases phosphorylation 18660423
C088327 JM 3100 JM 3100 inhibits the reaction [CXCL12 protein results in increased phosphorylation of NOS3 protein]decreases reaction|increases phosphorylation 18660423
C533894 LG 100815 LG 100815 results in decreased expression of CXCL12 mRNAdecreases expression 16951191
D015735 Mifepristone Mifepristone results in increased expression of CXCL12 mRNAincreases expression 17584828
C510003 nordy nordy inhibits the reaction [CXCL12 protein results in increased expression of IL8 mRNA]decreases reaction|increases expression 17415525
C510003 nordy nordy inhibits the reaction [CXCL12 protein results in increased expression of VEGFA mRNA]decreases reaction|increases expression 17415525
C062198 octa-2,4,6-trienoic acid octa-2,4,6-trienoic acid results in decreased expression of CXCL12 mRNAdecreases expression 16951191
C030110 oxaliplatin oxaliplatin results in decreased expression of CXCL12 mRNAdecreases expression 17762391
D010100 Oxygen Oxygen deficiency results in increased expression of and results in increased secretion of CXCL12 proteinincreases expression|increases secretion 18803305
D010100 Oxygen phenylmethylpyrazolone inhibits the reaction [Oxygen deficiency results in increased expression of and results in increased secretion of CXCL12 protein]decreases reaction|increases expression|increases secretion 18803305
D010100 Oxygen SDC2 protein promotes the reaction [Oxygen deficiency results in increased expression of and results in increased secretion of CXCL12 protein]increases expression|increases reaction|increases secretion 18803305
C041786 palm oil palm oil results in increased expression of CXCL12 mRNAincreases expression 18042831
D026023 Permethrin Permethrin results in increased expression of CXCL12 mRNAincreases expression 19017407
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of CXCL12 mRNA]affects reaction|decreases expression 19482888
D010634 Phenobarbital Phenobarbital results in decreased expression of CXCL12 mRNAdecreases expression 19482888
C005435 phenylmethylpyrazolone phenylmethylpyrazolone inhibits the reaction [Oxygen deficiency results in increased expression of and results in increased secretion of CXCL12 protein]decreases reaction|increases expression|increases secretion 18803305
C005435 phenylmethylpyrazolone phenylmethylpyrazolone inhibits the reaction [SDC2 protein results in increased expression of and results in increased secretion of CXCL12 protein]decreases reaction|increases expression|increases secretion 18803305
C006253 pirinixic acid pirinixic acid results in decreased expression of CXCL12 mRNAdecreases expression 17950772
18445702
16221962
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in decreased expression of CXCL12 mRNA]decreases expression|increases reaction 17950772
C045950 propiconazole propiconazole results in decreased expression of CXCL12 mRNAdecreases expression 19363144
D020849 Raloxifene [Raloxifene co-treated with ESR2 protein] results in increased expression of CXCL12 mRNAaffects cotreatment|increases expression 19059307
C059514 resveratrol resveratrol inhibits the reaction [CXCL12 protein affects the localization of Calcium]affects localization|decreases reaction 16212921
C089730 rosiglitazone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CXCL12 mRNAaffects cotreatment|decreases expression 16054899
C089730 rosiglitazone [Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CXCL12 mRNA]affects cotreatment|decreases expression|decreases reaction 16054899
C089730 rosiglitazone Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CXCL12 mRNA]affects cotreatment|decreases expression|decreases reaction 16054899
C017947 sodium arsenite sodium arsenite results in decreased expression of CXCL12 mRNAdecreases expression 17879257
D018038 Sodium Selenite Sodium Selenite inhibits the reaction [Hydrogen Peroxide results in increased expression of CXCL12 mRNA]decreases reaction|increases expression 17997286
D013629 Tamoxifen [Tamoxifen co-treated with ESR2 protein] results in increased expression of CXCL12 mRNAaffects cotreatment|increases expression 19059307
D013629 Tamoxifen Tamoxifen results in decreased methylation of CXCL12 promoterdecreases methylation 19748759
D013629 Tamoxifen Tamoxifen results in increased expression of CXCL12 mRNAincreases expression 19748759
D013629 Tamoxifen Tamoxifen results in increased expression of CXCL12 proteinincreases expression 19748759
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of CXCL12 mRNAaffects cotreatment|decreases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of CXCL12 mRNAdecreases expression 19619570
17517823
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of CXCL12 proteindecreases expression 17517823
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of CXCL12 mRNAincreases expression 17555868
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin binds to AHR protein] which results in decreased expression of CXCL12 mRNAaffects binding|decreases expression 16214954
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CXCL12 mRNA]affects cotreatment|decreases expression|decreases reaction 16054899
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with EGF protein] results in increased expression of CXCL12 mRNAaffects cotreatment|increases expression 16054899
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CXCL12 mRNA]affects cotreatment|decreases expression|decreases reaction 16054899
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin inhibits the reaction [EGF protein results in increased expression of CXCL12 mRNA]decreases reaction|increases expression 15667827
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of CXCL12 mRNAdecreases expression 18796159
16960034
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of CXCL12 mRNAincreases expression 16054899
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of CXCL12 mRNAincreases expression 16267337
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of CXCL12 mRNAincreases expression 16960034
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in increased expression of CXCL12 mRNAincreases expression 12880637
C012589 trichostatin A trichostatin A results in increased expression of CXCL12 mRNAincreases expression 19289100
D014302 Trinitrobenzenesulfonic Acid Trinitrobenzenesulfonic Acid results in increased expression of CXCL12 mRNAincreases expression 15973123
C025643 vinclozolin vinclozolin affects the expression of CXCL12 mRNAaffects expression 19015723
C509592 Zn(II) dipicolylamine Zn(II) dipicolylamine analog inhibits the reaction [CXCL12 protein binds to and results in increased activity of CXCR4 protein]affects binding|decreases reaction|increases activity 16722661
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 3.9314745880
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 6.326195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 6.3211752688 15322242 14514962
MESH:D000138 Acidosis Ammonium Chloride 2.9618287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.3317505938
MESH:D058186 Acute Kidney Injury resveratrol 3.3216538975
MESH:D055371 Acute Lung Injury Oxygen 7.3916759491
MESH:D055371 Acute Lung Injury pirinixic acid 7.3918653653
MESH:D000230 Adenocarcinoma Estradiol 5.9211473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 5.9214692618
MESH:D000230 Adenocarcinoma Fluorouracil 5.9217638652
MESH:D000236 Adenoma 2-Acetylaminofluorene 9.1610737359
MESH:D000236 Adenoma Diethylnitrosamine 9.166695378 10737359
MESH:D000236 Adenoma resveratrol 9.1615688382
MESH:D002759 Adenoma, Bile Duct 2-Acetylaminofluorene 5.396705139
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 19.9516434500 17620307 18056438 17162532 19061943 19052882
MESH:D018248 Adenoma, Liver Cell Phenobarbital 19.9517620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 19.9516434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 19.9516835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.0915276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.2916712894 17306315
MESH:D000419 Albuminuria Raloxifene 4.0217308373 17451421
MESH:D019973 Alcohol-Related Disorders Curcumin 4.4717887948
MESH:D000544 Alzheimer Disease 27-hydroxycholesterol 10.6520157255 14523054
MESH:D000544 Alzheimer Disease Curcumin 10.6515590663
MESH:D000544 Alzheimer Disease Raloxifene 10.6515800139
MESH:D000544 Alzheimer Disease resveratrol 10.6516162502 16183991
MESH:D000544 Alzheimer Disease rosiglitazone 10.6519621015
MESH:D000740 Anemia Fluorouracil 6.9416511603 15504547 17963324
MESH:D000740 Anemia Tetrachlorodibenzodioxin 6.9411748828
MESH:D000741 Anemia, Aplastic Benzene 3.9011369114 17661222 14761424
MESH:D000799 Angioedema Acetaminophen 3.2310982225
MESH:D000860 Anoxia Oxygen 4.4620872349
MESH:D001008 Anxiety Disorders vinclozolin 3.1619015723
MESH:D001161 Arteriosclerosis Cyclophosphamide 13.6915014928
MESH:D001161 Arteriosclerosis Dietary Fats 13.6915238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 13.6911256880
MESH:D001169 Arthritis, Experimental Dexamethasone 10.0417659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 10.0415885639
MESH:D001169 Arthritis, Experimental resveratrol 10.0417115116
MESH:D001172 Arthritis, Rheumatoid Curcumin 4.6816807698
MESH:D001172 Arthritis, Rheumatoid phenylmethylpyrazolone 4.6816390820
MESH:D050197 Atherosclerosis 27-hydroxycholesterol 12.629059518 11166758
MESH:D050197 Atherosclerosis Curcumin 12.6218704882
MESH:D050197 Atherosclerosis Oxygen 12.6216391483
MESH:D050197 Atherosclerosis resveratrol 12.6216873680 17967414
MESH:D001284 Atrophy fulvestrant 4.2811514358
MESH:D001321 Autistic Disorder Acetaminophen 1.5018445737
MESH:D001327 Autoimmune Diseases Curcumin 3.9119761891
MESH:D001778 Blood Coagulation Disorders pirinixic acid 6.9819483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 6.9812125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.1815340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.3615746008
MESH:D001855 Bone Marrow Diseases Benzene 4.6216183116
MESH:D001930 Brain Injuries Raloxifene 3.8916580743
MESH:D002545 Brain Ischemia beta Carotene 13.7416157235
MESH:D002545 Brain Ischemia Curcumin 13.7416770732
MESH:D002545 Brain Ischemia resveratrol 13.7417600658
MESH:D001932 Brain Neoplasms Curcumin 3.4217596214
MESH:D001943 Breast Neoplasms Benzene 11.2517162533 11921183
MESH:D001943 Breast Neoplasms Curcumin 11.2518462866 19250217 16243823 18593918
MESH:D001943 Breast Neoplasms Cyclophosphamide 11.2516978400 18234424 15136595 17388661 12006526 17020986 15093573 11325840 18323546
MESH:D001943 Breast Neoplasms decitabine 11.2518320071 19208741
MESH:D001943 Breast Neoplasms Dietary Fats 11.2520435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 11.2517474063
MESH:D001943 Breast Neoplasms Estradiol 11.2516675129 12948864 18497071 17289903 19861407 14630087 17018787 17261762
MESH:D001943 Breast Neoplasms Fluorouracil 11.2516595493 16110121 19217205 16557594 15136595 18357371 18608205
MESH:D001943 Breast Neoplasms fulvestrant 11.2518984771
MESH:D001943 Breast Neoplasms Oxygen 11.2517263869
MESH:D001943 Breast Neoplasms Raloxifene 11.2517893378 15572757 16912660 17242785 15758505 15775269 17595753 17440819 16837676 17952589 17261762 17049068
MESH:D001943 Breast Neoplasms resveratrol 11.2517534123 16393696 17651959
MESH:D001943 Breast Neoplasms Tamoxifen 11.2519189212 19289846 21152245 19066611 17261762 19410462 19011961 21138602 17893378 19059307 19155303 18425577 18815881 16873071 20390343 17242785 15668708 16818667 19189210 17049068 19221464 18997820 19115204 18821012 11161223 19487384 19084267 17440819 19200415 19288272 20544844 20065188 20859285 18984771 20135344 20005174 18629630 16273361 15565566 19103187 19244106 18351453 19142967 16202921 18855134
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 11.2520435547
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.8616111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.2015721981 16097048 16227642 18705752 10355542 16192424 15700767 16050911 15673190 16124888 3786805 16011737
MESH:D002276 Carcinoid Tumor Fluorouracil 4.0616051944
MESH:D002277 Carcinoma Curcumin 11.1818593918
MESH:D002277 Carcinoma Fluorouracil 11.1817121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 11.1816835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 3.9219066611
MESH:D006528 Carcinoma, Hepatocellular marker/mechanism 19363144
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 28.9316705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 28.9316705839
MESH:D006528 Carcinoma, Hepatocellular 2-Acetylaminofluorene 28.9317761372 10737359 3084413 6705139 3581430
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 28.933084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 28.9318788625
MESH:D006528 Carcinoma, Hepatocellular Cyclophosphamide 28.9319701751
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 28.9320727157 19539802 16569478 18785209 18506893 17428255 19919837 20935162 18788625 19052882 17173139 20084675 16288022 3581430 16878318 16807293 19701751 18393292 17138121 19335982 19171122 19394651 10672840 18210153 20514400 3084413 17978847 19822196 17761372 20512989 17055752 16502159 20524982 16540662 16698587 18971187 18691550 20101231 20432363 21159647 16935385 17162532 19383236 16328049 18978308 19107877 18494052 18056438 11831363 16681979 16830150 20214788 19519916 18665156 19418558 19208518 20007298 10737359 16779866
MESH:D006528 Carcinoma, Hepatocellular Estradiol 28.9316924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 28.9317971768 16332177 16799960 17045692 18930000 17088986
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 28.931701930 17173139 20007298 20935162 6705139
MESH:D006528 Carcinoma, Hepatocellular resveratrol 28.9316227395 19321006
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 28.9315276417 17306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 28.9316924424
MESH:D018827 Carcinoma, Lewis Lung Cyclophosphamide 9.4916152834
MESH:D018827 Carcinoma, Lewis Lung resveratrol 9.4916675471
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 2.7418414057
MESH:D002292 Carcinoma, Renal Cell Cyclophosphamide 5.7516201981
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 5.7518695887
MESH:D002294 Carcinoma, Squamous Cell Curcumin 15.2218462866
MESH:D002294 Carcinoma, Squamous Cell decitabine 15.2219215824
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 15.2217066447 18986760 16280240 16757204
MESH:D002294 Carcinoma, Squamous Cell resveratrol 15.2216227395
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 15.2218572023
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 15.2218922899
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 7.7617572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 7.7617572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.0116120746 18670907 18850075
MESH:D009202 Cardiomyopathies Zalcitabine 4.3010591146
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 9.7716936243
MESH:D002318 Cardiovascular Diseases Raloxifene 9.7715775269
MESH:D002318 Cardiovascular Diseases resveratrol 9.7715458977
MESH:D002386 Cataract Acetaminophen 2.2010977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 16.526135515
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 16.5220889678
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 16.527505956 2727394 17174075 21159647
MESH:D002471 Cell Transformation, Neoplastic Estradiol 16.5218566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 16.5219524636 20056578
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.674080065
MESH:D002543 Cerebral Hemorrhage phenylmethylpyrazolone 5.2419095969
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 7.6219052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 7.6216835633
MESH:D002779 Cholestasis Ethinyl Estradiol 6.2215861022 17333356 17110522 16105132 16919318 11677210 17681005
MESH:D002779 Cholestasis pirinixic acid 6.2219176532
MESH:D019457 Chromosome Breakage Sodium Selenite 4.1615894690
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 1.8215340226 15668235 8697196 16354765 12621046
MESH:D003072 Cognition Disorders Raloxifene 4.0315800139
MESH:D003092 Colitis Curcumin 12.8318200517 16804969 16782535
MESH:D003092 Colitis resveratrol 12.8316474422
MESH:D003092 Colitis Trinitrobenzenesulfonic Acid 12.8316804969 11698051 17936198 16782535 18023891 18200517 17991707 16474422 16867261
MESH:D003093 Colitis, Ulcerative Trinitrobenzenesulfonic Acid 3.2117276891
MESH:D003103 Coloboma Curcumin 4.0118809619
MESH:D003110 Colonic Neoplasms Curcumin 14.9016340194 19359593
MESH:D003110 Colonic Neoplasms decitabine 14.9017616700
MESH:D003110 Colonic Neoplasms Dexamethasone 14.9015824018
MESH:D003110 Colonic Neoplasms Fluorouracil 14.9015001691 17016597 16510598 17287894 18772588 17018589 16340194 17725105 17169374 17172411
MESH:D003110 Colonic Neoplasms irinotecan 14.9017725105 17287894
MESH:D003110 Colonic Neoplasms oxaliplatin 14.9016004971 16510598 16024531
MESH:D003110 Colonic Neoplasms resveratrol 14.9016338953
MESH:D015179 Colorectal Neoplasms Azacitidine 7.3119934284
MESH:D015179 Colorectal Neoplasms decitabine 7.3118981723
MESH:D015179 Colorectal Neoplasms Fluorouracil 7.3115148649 16391804 16303861 20501625 17454858 17094418 16282729 18448328 18383874 16524972 17401013 17255274 18802399 17695437 18509181 14970324 17594712 18288408 17016601 16331619 18949393 15289873
MESH:D015179 Colorectal Neoplasms irinotecan 7.3117454858 17159606 18509181 15273666 16303861 18259882 16391804
MESH:D015179 Colorectal Neoplasms oxaliplatin 7.3117255274 17594712 17401013 18448328 17695437 18509181
MESH:D015179 Colorectal Neoplasms resveratrol 7.3116550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.5517141729 14669216
MESH:D016510 Corneal Neovascularization Curcumin 4.3118497527
MESH:D003324 Coronary Artery Disease marker/mechanism 21378990
MESH:D003327 Coronary Disease resveratrol 3.3416507316
MESH:D019465 Craniofacial Abnormalities Benzene 4.7515643154
MESH:D019465 Craniofacial Abnormalities Dexamethasone 4.7517728286
MESH:D019465 Craniofacial Abnormalities Permethrin 4.7519861644
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 4.7520055451 10048152 15322242
MESH:D003456 Cryptorchidism vinclozolin 3.7714966744
MESH:D003490 Cyanosis 2,4-dinitrotoluene 8.9518551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 8.9518551238
MESH:D003556 Cystitis Cyclophosphamide 4.3715276878 12913760 18093676 18295254 18372110 18433785 16614059 18483878 16413132 17010015 10498854 16651033 15643279 11948286 12388444 10700343 18710439 12161096 16989017 17979934
MESH:D007644 Darier Disease Fluorouracil 4.1916733453
MESH:D003711 Demyelinating Diseases Tamoxifen 3.7719031437
MESH:D003715 Dengue 27-hydroxycholesterol 5.0819427377
MESH:D003865 Depressive Disorder, Major Raloxifene 3.6517474826
MESH:D003872 Dermatitis Benzene 4.1815902427
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 2.8612438553
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.1218249437
MESH:D003877 Dermatitis, Contact Permethrin 4.4414617103
MESH:D003920 Diabetes Mellitus rosiglitazone 7.7317446233
MESH:D003920 Diabetes Mellitus Sodium Selenite 7.7316285004
MESH:D003921 Diabetes Mellitus, Experimental Cyclophosphamide 7.0411751995 15331540 10990075
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 7.0416873680
MESH:D003922 Diabetes Mellitus, Type 1 Cyclophosphamide 3.0018772604
MESH:D003924 Diabetes Mellitus, Type 2 coumarin 11.5919647726
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 11.5918403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 11.5920387270
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 11.5912642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 11.5917107852
MESH:D003928 Diabetic Nephropathies Curcumin 22.6818204486
MESH:D003928 Diabetic Nephropathies Estradiol 22.6819279558
MESH:D003928 Diabetic Nephropathies Raloxifene 22.6815920148 17451421 17308373
MESH:D003928 Diabetic Nephropathies resveratrol 22.6816286809
MESH:D003928 Diabetic Nephropathies Tamoxifen 22.6819279558
MESH:D003967 Diarrhea Dexamethasone 3.147237001
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 18.2618551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 18.2621346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 18.2615619225 16227642 12540782 10915739 10774834 12705907 2444490 11461765 19923254 11421492 14550746 14986274 19420014 17906064 18713872 17522070 11743745 12958197 11739529 11834606 12392966 14725611 19085960 12153990 16485898 10663392 12594235 19416960 17562736 16781746 16177239 11287661 15968718 18071297 16393943 11529661 19164858 16081117 16109766 19739265 19370779
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 18.2616227642 7179309 9327722 2869522 3732212 7120509 16177239 6623471 10915739 6884620 19085960 15027814 21278145 10092053 17522070 11566570 3786805 19336974 15998439 4309450 7440962 15968718
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 18.2619107877
MESH:D056486 Drug-Induced Liver Injury fumonisin B1 18.2616221962
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 18.2615131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 18.2620420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.4919426721
MESH:D004362 Drug Toxicity phenylmethylpyrazolone 11.4212231392 12649298
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 11.4211462148
MESH:D004362 Drug Toxicity Zalcitabine 11.427515130
MESH:D004381 Duodenal Ulcer Curcumin 3.4817351913
MESH:D050171 Dyslipidemias Dietary Fats 3.0118367378
MESH:D004417 Dyspnea Oxygen 4.2320016425
MESH:D004421 Dystonia Phenobarbital 3.451851702
MESH:D004485 Eczema Dexamethasone 3.8912438553
MESH:D004487 Edema Dexamethasone 24.4519703484
MESH:D004487 Edema pirinixic acid 24.4512083418
MESH:D004487 Edema Raloxifene 24.4515860553
MESH:D004487 Edema resveratrol 24.458985016
MESH:D004487 Edema rosiglitazone 24.4512083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 24.4512711302 11000095
MESH:D004487 Edema Tetradecanoylphorbol Acetate 24.457812673 11698051 8113982 9599246 8273558 15177302 16716910
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.2915322242 18230668 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental 27-hydroxycholesterol 22.7317410599
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 22.7312538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 22.7315845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 22.7317872969
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 22.7319031437
MESH:D004701 Endocrine Gland Neoplasms decitabine 11.9919294695
MESH:D004701 Endocrine Gland Neoplasms trichostatin A 11.9919294695
MESH:D016889 Endometrial Neoplasms Estradiol 6.0111473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Tamoxifen 6.0117893378 16202921 19155303 20544844
MESH:D004715 Endometriosis Mifepristone 7.4116134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 7.419294722 10568697
MESH:D019446 Endotoxemia phenylmethylpyrazolone 4.8712954792
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.2617923197
MESH:D004802 Eosinophilia Cyclophosphamide 3.6411006010
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.523659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.2611558140 3922381
MESH:D004827 Epilepsy Phenobarbital 2.5520417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.046401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.677750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.423659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.5016302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 3.8620426865
MESH:D004938 Esophageal Neoplasms Fluorouracil 3.8616481741 15173087 17638652 16337965 16785472
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.5511564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 50.3112795759 61145 15959796 16239168 16045604 17595544 12631006 19224547
MESH:D005234 Fatty Liver Curcumin 50.3119297423
MESH:D005234 Fatty Liver Dietary Fats 50.3117967931 19551842 19004024 18296743
MESH:D005234 Fatty Liver Diethylnitrosamine 50.3120387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 50.3115345470
MESH:D005234 Fatty Liver phenylmethylpyrazolone 50.3112795759
MESH:D005234 Fatty Liver pirinixic acid 50.3119236843 20131406
MESH:D005234 Fatty Liver Raloxifene 50.3117473493
MESH:D005234 Fatty Liver rosiglitazone 50.3119196556
MESH:D005234 Fatty Liver Tamoxifen 50.3119224547 14986274
MESH:D005234 Fatty Liver Zalcitabine 50.3118299183
MESH:D052776 Female Urogenital Diseases Tamoxifen 2.8416709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.8711858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 3.9314745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.5819069698
MESH:D005355 Fibrosis Carbon Tetrachloride 21.5818705752
MESH:D005355 Fibrosis Curcumin 21.5818705752
MESH:D005355 Fibrosis Dietary Fats 21.5818296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 21.5820067830
MESH:D005355 Fibrosis Trinitrobenzenesulfonic Acid 21.5817994277
MESH:D005739 Gas Poisoning Oxygen 4.6120016425
MESH:D005756 Gastritis Acetaminophen 3.0616983495
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.1118462866
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.3316973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.6916417039
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.0816452187
MESH:D005909 Glioblastoma Curcumin 6.2217596214
MESH:D005909 Glioblastoma trichostatin A 6.2218801729
MESH:D005910 Glioma Fluorouracil 2.6016145905
MESH:D018316 Gliosarcoma Cyclophosphamide 4.9111389073
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.9810696789
MESH:D006086 Graft vs Host Disease Cyclophosphamide 4.4516376943 11014644 15172196
MESH:D006258 Head and Neck Neoplasms Curcumin 10.5718829502 18462866
MESH:D006258 Head and Neck Neoplasms decitabine 10.5719215824
MESH:D006258 Head and Neck Neoplasms Fluorouracil 10.5715102660 15162350 18337622
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 1.9911294989 10048152
MESH:D006331 Heart Diseases Raloxifene 3.1111110106
MESH:D006333 Heart Failure pirinixic acid 2.1520558911
MESH:D006390 Hemangioendothelioma 2-Acetylaminofluorene 4.706705139
MESH:D006394 Hemangiosarcoma 2-Acetylaminofluorene 3.876705139
MESH:D006402 Hematologic Diseases Benzene 4.1016183116
MESH:D006467 Hemophilia A Cyclophosphamide 4.7011918545
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.8011000095
MESH:D006504 Hepatic Veno-Occlusive Disease Cyclophosphamide 4.9214986274
MESH:D006505 Hepatitis Carbon Tetrachloride 3.0319900420 19110552
MESH:D006529 Hepatomegaly 1,4-bis(2-(3,5-dichloropyridyloxy))benzene 26.2316109766
MESH:D006529 Hepatomegaly fumonisin B1 26.2316221962
MESH:D006529 Hepatomegaly Phenobarbital 26.2316109766
MESH:D006529 Hepatomegaly pirinixic acid 26.2319176532 16221962 18467677 19772884
MESH:D006529 Hepatomegaly propiconazole 26.2317178688 17178689
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 26.2316120746 15340226 12621046
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.4517701891
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 2.837520565
MESH:D006558 Herpes Genitalis Estradiol 4.4215709030
MESH:D006561 Herpes Simplex resveratrol 3.5916876885
MESH:D015658 HIV Infections beta Carotene 6.3216960176
MESH:D015658 HIV Infections Zalcitabine 6.3217457083
MESH:D006689 Hodgkin Disease Cyclophosphamide 5.9516135485 17606976
MESH:D006689 Hodgkin Disease sodium arsenite 5.9512676792
MESH:D019584 Hot Flashes Estradiol 3.1417088409
OMIM:609423 HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO marker/mechanism
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.4318606429 8697196 15340226 16354765 16959395
MESH:D006930 Hyperalgesia Acetaminophen 10.4716870215
MESH:D006930 Hyperalgesia oxaliplatin 10.4717418472
MESH:D006930 Hyperalgesia rosiglitazone 10.4712083418
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.9316899240
MESH:D006937 Hypercholesterolemia 27-hydroxycholesterol 17.4717873880
MESH:D006937 Hypercholesterolemia Curcumin 17.4718704882
MESH:D006937 Hypercholesterolemia Dietary Fats 17.4721332399
MESH:D006937 Hypercholesterolemia resveratrol 17.4717188708
MESH:D006943 Hyperglycemia pirinixic acid 2.6620558911
MESH:D006949 Hyperlipidemias Dietary Fats 7.4521332399
MESH:D006949 Hyperlipidemias resveratrol 7.4516873680
MESH:D006973 Hypertension Benzene 10.2017940673
MESH:D006973 Hypertension Dexamethasone 10.2017042910
MESH:D006973 Hypertension Raloxifene 10.2017577099 15787275
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 10.2018670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.5015338365
MESH:D017379 Hypertrophy, Left Ventricular phenylmethylpyrazolone 9.0315824197
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 9.0317488730
MESH:D007021 Hypospadias Ethinyl Estradiol 3.2216569931 16945680
MESH:D007077 Ileal Diseases 1-Methyl-3-isobutylxanthine 4.8318306037
MESH:D007154 Immune System Diseases Cyclophosphamide 4.7216076520
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.0617600658
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.9112013081
MESH:D007248 Infertility, Male Cyclophosphamide 20.9316517039 7193160
MESH:D007248 Infertility, Male decitabine 20.9317581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 20.9317937319
MESH:D007248 Infertility, Male fulvestrant 20.9311514358
MESH:D007248 Infertility, Male sodium arsenite 20.9312646999 15346721
MESH:D007248 Infertility, Male vinclozolin 20.9316467254
MESH:D007249 Inflammation Curcumin 26.3018403477 16956363 17151092
MESH:D007249 Inflammation Dexamethasone 26.3011099482 8960868
MESH:D007249 Inflammation Dietary Fats 26.3020412841
MESH:D007249 Inflammation Diethylnitrosamine 26.3018785209
MESH:D007249 Inflammation resveratrol 26.3016366677
MESH:D007249 Inflammation rosiglitazone 26.3012083418
MESH:D007249 Inflammation Tamoxifen 26.3019457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 26.3012200463 12878042
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 26.3015177302 8273558 11698051 7812673 7562506
MESH:D015212 Inflammatory Bowel Diseases Curcumin 5.7618596194 18200517
MESH:D015212 Inflammatory Bowel Diseases Trinitrobenzenesulfonic Acid 5.7618200517
MESH:D007251 Influenza, Human resveratrol 3.9316624496
MESH:D007299 Insect Bites and Stings Permethrin 5.2115189238 12749493 12971516
MESH:D007333 Insulin Resistance Dietary Fats 18.8011836018 18457598
MESH:D007333 Insulin Resistance Estradiol 18.8016393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 18.8016306350
MESH:D007333 Insulin Resistance rosiglitazone 18.8016306350
MESH:D007333 Insulin Resistance Sodium Selenite 18.8014714311
MESH:D007410 Intestinal Diseases Trinitrobenzenesulfonic Acid 4.0317994277
MESH:D007414 Intestinal Neoplasms Curcumin 3.6910783313
MESH:D002532 Intracranial Aneurysm phenylmethylpyrazolone 4.7619381132
MESH:D007511 Ischemia phenylmethylpyrazolone 4.9616301206
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 2.8016580747
MESH:D007579 Jejunal Diseases 1-Methyl-3-isobutylxanthine 4.8318306037
MESH:D007674 Kidney Diseases Acetaminophen 11.4215629191 12587719
MESH:D007674 Kidney Diseases Estradiol 11.4215618244
MESH:D007674 Kidney Diseases phenylmethylpyrazolone 11.4218085390
MESH:D007674 Kidney Diseases sodium arsenite 11.4220008137
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 3.7316518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 18.1216705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 18.1216705839
MESH:D007680 Kidney Neoplasms Estradiol 18.1215610895
MESH:D007680 Kidney Neoplasms Fluorouracil 18.1216985049
MESH:D007680 Kidney Neoplasms Tamoxifen 18.1218625569
MESH:D007683 Kidney Tubular Necrosis, Acute Calcium 4.4316316344
MESH:D007889 Leiomyoma Curcumin 9.3118555241
MESH:D007889 Leiomyoma Raloxifene 9.3116973256
MESH:D007938 Leukemia Azacitidine 20.3119148494
MESH:D007938 Leukemia Benzene 20.3117119257 14694614 15935818 18335105
MESH:D007938 Leukemia Curcumin 20.3118462866
MESH:D007938 Leukemia Cyclophosphamide 20.3110602166
MESH:D007938 Leukemia decitabine 20.3118980019 19235587
MESH:D007938 Leukemia Permethrin 20.3112937054
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Cyclophosphamide 3.2117658394 17802794 17296974 17008537 18587576 18172266
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 3.6716106398
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Cyclophosphamide 3.6310373061
MESH:D007951 Leukemia, Myeloid Azacitidine 13.0819077051
MESH:D007951 Leukemia, Myeloid Benzene 13.0817506065
MESH:D007951 Leukemia, Myeloid decitabine 13.0818454857 19117987 17236224
MESH:D015470 Leukemia, Myeloid, Acute Azacitidine 7.6218720364 17596541
MESH:D015470 Leukemia, Myeloid, Acute Benzene 7.6219478238
MESH:D015470 Leukemia, Myeloid, Acute decitabine 7.6218206229 18460780 19387464 17679729 18704418 19010910
MESH:D015470 Leukemia, Myeloid, Acute trichostatin A 7.6218206229
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 4.8518055864
MESH:D054429 Leukemia, Myelomonocytic, Juvenile Azacitidine 4.6319299654
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 3.1716087638
MESH:D015458 Leukemia, T-Cell Curcumin 4.1916106398
MESH:D007970 Leukopenia Cyclophosphamide 4.3710052129 11830472
MESH:D007984 Leydig Cell Tumor vinclozolin 4.1316417039
MESH:D008064 Lipidoses Tamoxifen 2.7115342952 17567588
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 12.7711408273 11903743 16239168 21278145 16221502 17174718 16943688 17334410 17157831
MESH:D008103 Liver Cirrhosis Dietary Fats 12.7718296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 12.7720032147 18407596 18665156 19638242 18522880
MESH:D008103 Liver Cirrhosis Phenobarbital 12.7721047994
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 11.3618472332 15996030 18166357 10355542 14748882 12741479 16015684 16011737 18277467 18251166 17823541 16027843 20821823 15057751 12666154 15818738 15650968 14716833 15893842 18279442 14724832 18395095 18481824 17976157 11481614 18317297 14716496 15123356 17565644 15876570 12898905 18418968 12632514 12958196 17698563 15052691 18412020 17944888 15338365 18376398 16638106 17721639 17805973 17640975 15925388 16033810 18006644 18429990 17922224 17714472 18210741 17631135 14620537 16097048 16248980 12609069 18395914 18156304 18472094 16192424 18054572 18339082 15931870 18263696 12649538 15959796 12546737 17525996 17481882 18420326 15730626 13678700 17869086 12667390 16136751 12445421 12445418 17761835 15673190 15362042 15370692 18187930 14512876 18705752 17557913 12632512 12389079 12586293 17900296 18205269 17708605 16116963 17766677
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 11.3618006644 17355460 18705752
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 11.3616718785
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 11.3614716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 11.3615474484
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 11.3615980055 17347453
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 11.3618564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 11.3612878042
MESH:D008107 Liver Diseases Acetaminophen 13.2512969438 11587558 19460945 12587719 19014921 16610002 19784758 16611625
MESH:D008107 Liver Diseases Carbon Tetrachloride 13.2516246199 15720792 16964402 15830285 17285989
MESH:D008107 Liver Diseases Curcumin 13.2516956363
MESH:D008107 Liver Diseases Diethylnitrosamine 13.2517034775
MESH:D008107 Liver Diseases Phenobarbital 13.2519363144
MESH:D008107 Liver Diseases propiconazole 13.2519363144
MESH:D017093 Liver Failure Carbon Tetrachloride 3.5815123358
MESH:D017114 Liver Failure, Acute Acetaminophen 7.6617185352 16871587
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 7.6616899240 14706259
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 44.317678174
MESH:D008113 Liver Neoplasms 2-Acetylaminofluorene 44.3110737359 11376686 14678523 18001218 16273603 10672840
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 44.3119294768
MESH:D008113 Liver Neoplasms ciprofibrate 44.3112771043
MESH:D008113 Liver Neoplasms Clofibric Acid 44.3117602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 44.3120118626 19690152 19294768 18754104 20501860 18644402 21167192 21047994 19642983 9163691 19073162 19833225 20405173 19256749 20434301 20452335 19850985 19426721 2422723 21278145 19996281 19499222 20101389 20137499 20492335 19638242 19255062 12771043 18978307 19812893 15175105 12112319 19090486 18977376 19551842 10737359 20583210 18648771 19254457 19427195 2862719 15885732 16942905 21071580
MESH:D008113 Liver Neoplasms Fluorouracil 44.3115113037 17045692 18383874 16603448
MESH:D008113 Liver Neoplasms Phenobarbital 44.3115975961 19482888 19073162 21047994 19812893 8742319
MESH:D008113 Liver Neoplasms pirinixic acid 44.3120007298 15890375 16377806
MESH:D008113 Liver Neoplasms propiconazole 44.3119028983
MESH:D008113 Liver Neoplasms resveratrol 44.3120405173 19812893 19073162 19321006
MESH:D008113 Liver Neoplasms sodium arsenite 44.3116712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 44.3116684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 44.3116984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 30.532876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental 2-Acetylaminofluorene 30.531399818 6150874 534488
MESH:D008114 Liver Neoplasms, Experimental Benzene 30.5312562636
MESH:D008114 Liver Neoplasms, Experimental beta Carotene 30.5317113696
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 30.5315583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 30.5319009564 18093689 18775883 3124819 16267830 17942915 19539802 18164116 18544905 18308698 18079962 19126423 17854601 9362446 21159647 17174075 2563599 18282651 18253720 19004024 16842330 19519916
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 30.532563599 1399818 6150874 18308698 17172636
MESH:D008114 Liver Neoplasms, Experimental propiconazole 30.5317178689
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 30.5312151625
MESH:D008171 Lung Diseases sodium arsenite 2.7519095001
MESH:D017563 Lung Diseases, Interstitial Benzene 4.2014698565
MESH:D055370 Lung Injury Oxygen 3.9318339021
MESH:D008175 Lung Neoplasms 2-Acetylaminofluorene 20.4611376686
MESH:D008175 Lung Neoplasms Azacitidine 20.4621224363
MESH:D008175 Lung Neoplasms Benzene 20.4612562636
MESH:D008175 Lung Neoplasms beta Carotene 20.4616401635
MESH:D008175 Lung Neoplasms Curcumin 20.4619359593 18462866 16243823
MESH:D008175 Lung Neoplasms Dexamethasone 20.4611195469 15824018
MESH:D008175 Lung Neoplasms Diethylnitrosamine 20.4621163286 6695378 20970405 20512841
MESH:D008175 Lung Neoplasms Fluorouracil 20.4615246190
MESH:D008175 Lung Neoplasms sodium arsenite 20.4619931552 17077188 17306315 16712894 15276417
MESH:D008175 Lung Neoplasms Tamoxifen 20.4618625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 20.4611884234 19555203
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 20.4611807781
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.1915086387
MESH:D008223 Lymphoma Benzene 18.7917119257 17584886
MESH:D008223 Lymphoma Curcumin 18.7918462866
MESH:D008223 Lymphoma Cyclophosphamide 18.7912854902
MESH:D008223 Lymphoma decitabine 18.7919470736
MESH:D008223 Lymphoma Zalcitabine 18.799205081 9488045 11980663 18798262 8764131 17941976 8840982
MESH:D016393 Lymphoma, B-Cell Cyclophosphamide 14.0016675587
MESH:D016393 Lymphoma, B-Cell resveratrol 14.0017088997
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 14.0014737004
MESH:D008228 Lymphoma, Non-Hodgkin Cyclophosphamide 7.3711911406
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 7.3714749477
MESH:D016399 Lymphoma, T-Cell Curcumin 4.1116173963
MESH:D015674 Mammary Neoplasms, Animal Benzene 13.3612562636
MESH:D015674 Mammary Neoplasms, Animal resveratrol 13.3615688416
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 13.3619428831
MESH:D008325 Mammary Neoplasms, Experimental Benzene 18.3011921183
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 18.3011807958 11408345 16891317 17203775
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 18.3011606380 8985016
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 18.3016827153
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 18.3011731420 16827153 14580682 19196722 19196723
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 18.308985016
MESH:D020149 Manganese Poisoning Estradiol 10.6119453300
MESH:D020149 Manganese Poisoning Tamoxifen 10.6119453300
MESH:D008545 Melanoma Curcumin 10.6017885582 18462866
MESH:D008545 Melanoma decitabine 10.6017785578 16505122
MESH:D008545 Melanoma resveratrol 10.6017992120
MESH:D008545 Melanoma sodium arsenite 10.6019082730 16487513
MESH:D008545 Melanoma Tamoxifen 10.6019393235 12393984
MESH:D008545 Melanoma trichostatin A 10.6016505122
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.5815990972
MESH:D008546 Melanoma, Experimental Acetaminophen 8.8919513568
MESH:D008546 Melanoma, Experimental Cyclophosphamide 8.8916388313
MESH:D008569 Memory Disorders Curcumin 3.5917263510
MESH:D008659 Metabolic Diseases phenylmethylpyrazolone 9.2416301206
MESH:D008659 Metabolic Diseases resveratrol 9.2417112576
MESH:D024821 Metabolic Syndrome X rosiglitazone 3.8817261469
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 4.9415863610
MESH:D009006 Monosomy Azacitidine 5.4719299654
MESH:D009062 Mouth Neoplasms Fluorouracil 3.1618986760 16757204
MESH:D052016 Mucositis irinotecan 4.4117159606
MESH:D009101 Multiple Myeloma Azacitidine 32.1718443271 19549372
MESH:D009101 Multiple Myeloma Benzene 32.1717119195
MESH:D009101 Multiple Myeloma Curcumin 32.1719372569
MESH:D009101 Multiple Myeloma decitabine 32.1718172295
MESH:D009101 Multiple Myeloma Dexamethasone 32.1715867202 16118317 15744524
MESH:D009101 Multiple Myeloma Raloxifene 32.1716497877
MESH:D009101 Multiple Myeloma resveratrol 32.1717935668 17049120 14749477 16490592 16267019 17164350
MESH:D009101 Multiple Myeloma trichostatin A 32.1718172295
MESH:D009134 Muscular Atrophy, Spinal Curcumin 10.4217962980
MESH:D009134 Muscular Atrophy, Spinal resveratrol 10.4217962980
MESH:D009135 Muscular Diseases pirinixic acid 2.9216239165
MESH:D009190 Myelodysplastic Syndromes Azacitidine 10.3518720364 17596541 19805378 17611569
MESH:D009190 Myelodysplastic Syndromes decitabine 10.3519010910 18608210 16882708 19157545
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 10.359809623
MESH:D009203 Myocardial Infarction pirinixic acid 4.7819151258
MESH:D009203 Myocardial Infarction resveratrol 4.7817188708 16317513 17125593 17015251 16525036 16456233
MESH:D017202 Myocardial Ischemia resveratrol 7.4017125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 7.4012213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 6.6816810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 6.6816411023
MESH:D009205 Myocarditis resveratrol 4.1617322642
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 3.8717484760
MESH:D009232 Myxoma Raloxifene 4.9416343187
MESH:D009336 Necrosis 2,4-dinitrotoluene 8.3618551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 8.3618551238 7678174
MESH:D009361 Neoplasm Invasiveness Curcumin 3.8018495463
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 7.913581430 9029167
MESH:D009362 Neoplasm Metastasis irinotecan 7.9118259882
MESH:D009362 Neoplasm Metastasis Tamoxifen 7.9119393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.2919410462
MESH:D009369 Neoplasms beta Carotene 15.4817051425
MESH:D009369 Neoplasms Cyclophosphamide 15.4818854779
MESH:D009369 Neoplasms decitabine 15.4819116145 17925555 19470736
MESH:D009369 Neoplasms Fluorouracil 15.4818600527 18239605 16928823
MESH:D009369 Neoplasms pirinixic acid 15.4817405874
MESH:D009369 Neoplasms sodium arsenite 15.4811559025
MESH:D009374 Neoplasms, Experimental resveratrol 12.128985016
MESH:D009374 Neoplasms, Experimental sodium arsenite 12.1220056578
MESH:D009374 Neoplasms, Experimental Zalcitabine 12.129205081 9488045 8764131
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 8.8112497104
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 8.8119189210 19196722 19200415
MESH:D009389 Neovascularization, Pathologic Estradiol 3.1417289903
MESH:D009421 Nervous System Malformations Estradiol 7.5716427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 7.5714600291
MESH:D009423 Nervous System Neoplasms Curcumin 5.0218462866
MESH:D009437 Neuralgia Zalcitabine 5.7117292584
MESH:D009436 Neural Tube Defects Benzene 6.1615643154
MESH:D009436 Neural Tube Defects sodium arsenite 6.1612854658
MESH:D009447 Neuroblastoma Cyclophosphamide 6.1516115947 8761367 15176712
MESH:D009447 Neuroblastoma irinotecan 6.158761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 11.1918514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 11.1920387270
MESH:D019636 Neurodegenerative Diseases resveratrol 11.1917652729
MESH:D017599 Neuroectodermal Tumors Cyclophosphamide 9.5412837982 8761367
MESH:D017599 Neuroectodermal Tumors irinotecan 9.548761367
MESH:D020078 Neurogenic Inflammation resveratrol 3.8417929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.5020387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.0116436463
MESH:D009503 Neutropenia Cyclophosphamide 3.788291058
MESH:D009765 Obesity Curcumin 6.3019297423
MESH:D009765 Obesity Dietary Fats 6.3017217161 16723640 21332399 20132043 19632207 20518802 18674790 11836018 18457598
MESH:D009765 Obesity pirinixic acid 6.3020558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 12.1416049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 12.1416049721
MESH:D009784 Occupational Diseases Benzene 12.1415935809 17178637 15913788 15727169 16737584 17119257 15612468 17479406 15576619
MESH:D009845 Oligospermia Cyclophosphamide 4.1116517039
MESH:D010018 Osteomalacia Phenobarbital 3.7617016548
MESH:D010024 Osteoporosis Calcium 9.7417882678
MESH:D010024 Osteoporosis Curcumin 9.7418719352
MESH:D010024 Osteoporosis Raloxifene 9.7417882678 19059307 15775268
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 8.3617823083 15758505 15579764 17893378
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 8.3617513867
MESH:D010051 Ovarian Neoplasms Benzene 19.3512562636
MESH:D010051 Ovarian Neoplasms Curcumin 19.3518462866 19020741
MESH:D010051 Ovarian Neoplasms decitabine 19.3519259094 19331143
MESH:D010051 Ovarian Neoplasms Estradiol 19.3519401270
MESH:D010051 Ovarian Neoplasms Mifepristone 19.3516525653
MESH:D010051 Ovarian Neoplasms sodium arsenite 19.3515276417 17306315
MESH:D010051 Ovarian Neoplasms trichostatin A 19.3519331143
MESH:D010146 Pain Acetaminophen 5.2416870215
MESH:D010146 Pain Cyclophosphamide 5.2418093676 12161096
MESH:D010190 Pancreatic Neoplasms Curcumin 24.8217440100 19196508 19401701
MESH:D010190 Pancreatic Neoplasms Cyclophosphamide 24.8211332152
MESH:D010190 Pancreatic Neoplasms decitabine 24.8219294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 24.8216540662
MESH:D010190 Pancreatic Neoplasms Fluorouracil 24.8219003803 16929163 16500647 15113037
MESH:D010190 Pancreatic Neoplasms Phenobarbital 24.8216965848
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 24.8215976015
MESH:D010190 Pancreatic Neoplasms trichostatin A 24.8219294695
MESH:D010195 Pancreatitis phenylmethylpyrazolone 7.3620035747
MESH:D010195 Pancreatitis Trinitrobenzenesulfonic Acid 7.3617698068
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.1311578682
MESH:D010212 Papilloma Hydrogen Peroxide 7.6812065085
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 7.6812065085 8330346 18404319 18922899
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.6312520081
MESH:D010523 Peripheral Nervous System Diseases Zalcitabine 4.7318606552
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.9918163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 7.392563599
MESH:D011230 Precancerous Conditions Phenobarbital 7.392563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Cyclophosphamide 6.5921297632
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 6.5921297632
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 12.8216679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 12.8211896295 11118676 11222880 11399792
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 12.8218042343 18220299 19015723
MESH:D055728 Primary Myelofibrosis decitabine 10.4817616702
MESH:D055728 Primary Myelofibrosis trichostatin A 10.4817616702
MESH:D011469 Prostatic Diseases vinclozolin 4.3318220299
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.3420887781
MESH:D011471 Prostatic Neoplasms marker/mechanism 17785557
MESH:D011471 Prostatic Neoplasms Azacitidine 3.7718324645
MESH:D011471 Prostatic Neoplasms Curcumin 3.7715129424 18156803 10851300 12497104 11398177 18769126 18226269
MESH:D011471 Prostatic Neoplasms Cyclophosphamide 3.7717136230
MESH:D011471 Prostatic Neoplasms Estradiol 3.7716740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 3.7718626508 19082440
MESH:D011471 Prostatic Neoplasms Raloxifene 3.7716220300 16536755 15731164
MESH:D011471 Prostatic Neoplasms resveratrol 3.7717804756 17636462 16731767 17718901 15767336 17675339
MESH:D011471 Prostatic Neoplasms sodium arsenite 3.7716039940
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.7718760546
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.7715067354
MESH:D011471 Prostatic Neoplasms trichostatin A 3.7718798265 19789329
MESH:D011472 Prostatitis vinclozolin 4.3318629315
MESH:D011537 Pruritus Ethinyl Estradiol 2.7216919318 15861022
MESH:D019310 Pseudolymphoma Phenobarbital 3.8812752131
MESH:D011649 Pulmonary Alveolar Proteinosis 27-hydroxycholesterol 5.7815466366
MESH:D011656 Pulmonary Emphysema Curcumin 4.0019168576
MESH:D011658 Pulmonary Fibrosis Cyclophosphamide 3.0216636934
MESH:D011693 Purpura Raloxifene 4.9415770314
MESH:D012004 Rectal Neoplasms Fluorouracil 3.5016160472 18286688 18722050 15538739
MESH:D051436 Renal Insufficiency, Chronic resveratrol 4.9716325855
MESH:D015427 Reperfusion Injury phenylmethylpyrazolone 9.2016753835 16041266 14654979 15086910 15948865 15629865
MESH:D015427 Reperfusion Injury pirinixic acid 9.2019058328
MESH:D015427 Reperfusion Injury resveratrol 9.2017520802 16314181 16317513 15827377 17058453
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 12.1410666014 18379247
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 12.1418379247 11700416
MESH:D012128 Respiratory Distress Syndrome, Adult Oxygen 12.1418339021 17627322
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.2618990726
MESH:D012208 Rhabdomyosarcoma decitabine 3.8519155313
MESH:D012509 Sarcoma Curcumin 3.5918462866
MESH:D012595 Scleroderma, Systemic Cyclophosphamide 4.2616636934
MESH:D012640 Seizures 2,4-dinitrotoluene 7.3518551238
MESH:D012640 Seizures 2,6-dinitrotoluene 7.3518551238
MESH:D012640 Seizures Phenobarbital 7.3511442880 16876388 4039156 3137016
MESH:D003294 Seizures, Febrile Phenobarbital 4.226407741
MESH:D018805 Sepsis Curcumin 3.5818389075
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 14.5412065085
MESH:D012878 Skin Neoplasms resveratrol 14.5415837718 8985016
MESH:D012878 Skin Neoplasms sodium arsenite 14.5419524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 14.5416192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 14.548985016 11807781 18404319 12065085 8330346
MESH:D019082 Smith-Lemli-Opitz Syndrome 27-hydroxycholesterol 5.4311254748
OMIM:270800 SPASTIC PARAPLEGIA 5A, AUTOSOMAL RECESSIVE 27-hydroxycholesterol 5.7719812052
MESH:D013088 Spermatocele Ethinyl Estradiol 9.5316709447
MESH:D013088 Spermatocele Tamoxifen 9.5316709447
OMIM:102530 SPERMATOGENIC FAILURE 6 Cyclophosphamide 4.9116517039
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.4419457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.3212854658
MESH:D013272 Stomach Diseases beta Carotene 8.6317638125
MESH:D013272 Stomach Diseases Dexamethasone 8.6315472012
MESH:D013274 Stomach Neoplasms Benzene 5.5012562636
MESH:D013274 Stomach Neoplasms decitabine 5.5019037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 5.5018456281
MESH:D013274 Stomach Neoplasms Fluorouracil 5.5018567086 15786421 17498489 17172411 19015929 19084572 16951190 16424979 18396642 17522103
MESH:D013274 Stomach Neoplasms irinotecan 5.5015723263
MESH:D013276 Stomach Ulcer beta Carotene 9.2112500499
MESH:D013276 Stomach Ulcer Curcumin 9.2116631530 19188055
MESH:D013276 Stomach Ulcer Dexamethasone 9.2115138204
MESH:D020521 Stroke Raloxifene 3.3416837676
OMIM:601367 STROKE, ISCHEMIC resveratrol 3.9516321402
MESH:D013398 Sudden Infant Death Oxygen 4.9412563064
MESH:D015173 Supratentorial Neoplasms Cyclophosphamide 4.4612837982
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.0611994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.6415669648
MESH:D013953 Thymus Neoplasms Benzene 4.3610850423
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.2912697716
MESH:D013964 Thyroid Neoplasms decitabine 9.3217967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 9.327505956
MESH:D013964 Thyroid Neoplasms Phenobarbital 9.321399818
MESH:D013978 Tibial Fractures Estradiol 11.6719048282
MESH:D013978 Tibial Fractures Raloxifene 11.6719048282
MESH:D014062 Tongue Neoplasms Fluorouracil 8.2416280240
MESH:D014062 Tongue Neoplasms resveratrol 8.2416227395
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 27.5416049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 27.5416049721
MESH:D001749 Urinary Bladder Neoplasms 2-Acetylaminofluorene 27.5415867355 15289314 1399818
MESH:D001749 Urinary Bladder Neoplasms Curcumin 27.5418593936
MESH:D001749 Urinary Bladder Neoplasms Cyclophosphamide 27.5414692829
MESH:D001749 Urinary Bladder Neoplasms decitabine 27.5417616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 27.5417572228
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 27.5411723127 17306315 16712894 16452187
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 27.5416712894 8653321 17572228
MESH:D014565 Urogenital Neoplasms Curcumin 4.6618462866
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 9.9910091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 9.9910091137
MESH:D014581 Urticaria Acetaminophen 2.4310982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 12.8816803524
MESH:D002583 Uterine Cervical Neoplasms resveratrol 12.8817473185
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 12.8811813266
MESH:D014594 Uterine Neoplasms Benzene 12.8212562636
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 12.8214692618
MESH:D014594 Uterine Neoplasms resveratrol 12.8217044934
MESH:D014604 Uveal Neoplasms decitabine 4.3017785578
MESH:D014605 Uveitis Dexamethasone 4.211336536
MESH:D014652 Vascular Diseases sodium arsenite 3.8217056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.9812125929
MESH:D014689 Venous Insufficiency coumarin 5.1612708602
MESH:D054556 Venous Thromboembolism Raloxifene 4.5916837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.0014671159 15869587
MESH:D018487 Ventricular Dysfunction, Left resveratrol 3.7217488730
MESH:D014846 Vulvar Neoplasms Raloxifene 4.9416343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.6315886252
MESH:D015430 Weight Gain Dietary Fats 3.2316723640
Pathway ID Pathway Name
KEGG:04360 Axon guidance
KEGG:04062 Chemokine signaling pathway
KEGG:04060 Cytokine-cytokine receptor interaction
KEGG:04672 Intestinal immune network for IgA production
KEGG:04670 Leukocyte transendothelial migration
KEGG:05323 Rheumatoid arthritis
REACT:14797 Signaling by GPCR
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA35602
    • No data
    No data
    Releated drug ID Related drug Name
    PA450218levonorgestrel
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB06822 binder Tinzaparin Anticoagulants;Antithrombotics
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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