AutismKB 2.0

Annotation Detail for SDF2


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Basic Information Top
Gene Symbol:SDF2 ( - )
Gene Full Name: stromal cell-derived factor 2
Band: 17q11.2
Quick LinksEntrez ID:6388; OMIM: 602934; Uniprot ID:SDF2_HUMAN; ENSEMBL ID: ENSG00000132581; HGNC ID: 10675
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of SDF2 mRNAdecreases expression 18648102
D004054 Diethylstilbestrol Diethylstilbestrol results in decreased expression of SDF2 mRNAdecreases expression 16636312
D007657 Ketone Bodies Ketone Bodies results in increased expression of SDF2 mRNAincreases expression 16807920
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.983712494
MESH:D000686 Amyloidosis Diethylstilbestrol 5.0615469931
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.8911289319 1440618
MESH:D001943 Breast Neoplasms Diethylstilbestrol 2.5815324884 17129689
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 3.293581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 3.2915948411 16924424
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.847296757
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 3.057505956
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 3.479022650 19486331
MESH:D003456 Cryptorchidism Diethylstilbestrol 5.1416002989 12952375
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 3.4411298694 8156756 8970840 2524372 11906362 14531868 12868966 18759878
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 4.023621924 2952479
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 2.0518289764 8291058 16192314 6482804 7440962 18692083 9653073 9022650 6679447 9328219 11289319 18648102 1440618
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 5.4316402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 3.7315700306 16804899
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.193581430
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.8916611131 15751030 16534752 16002989 16513791
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.896705139
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 5.6916452187
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.577505956
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 4.106705139
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 13.1115034207
MESH:D006965 Hyperplasia Diethylstilbestrol 13.1112960047 14722030
MESH:D007021 Hypospadias Diethylstilbestrol 5.2316002989
MESH:D007246 Infertility Diethylstilbestrol 4.9415036965
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.899022650 8074119
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 8.856582329
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 8.8514681315 16762066 15003126
MESH:D007859 Learning Disorders Diethylstilbestrol 4.7117184923
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.449327722 15034207
MESH:D008113 Liver Neoplasms Diethylstilbestrol 2.7616712894 15890375
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 2.783712494 1399818 6587162 598648
MESH:D008181 Lupus Nephritis Diethylstilbestrol 5.8915166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.7815700306
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 6.3816002989
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.613581430
MESH:D009369 Neoplasms Diethylstilbestrol 2.9415313581
MESH:D009421 Nervous System Malformations Diethylstilbestrol 4.7211399458
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 3.186679447
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.874026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.893988306
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 4.137296757
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 5.346228378
MESH:D010900 Pituitary Diseases Diethylstilbestrol 6.0414722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 5.3216977796 15687265
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 4.8517184923
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 3.5015046698 17136230 15846301
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.703692021
MESH:D013088 Spermatocele Diethylstilbestrol 5.5816002989 16709447
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 3.221399818 3712494 6587162 6582329 7505956
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 5.658074119
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 5.6516712894 17306315 16452187
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 4.4816175088
MESH:D014591 Uterine Diseases Diethylstilbestrol 6.0414652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 4.6515809267 16690809
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 5.0916002989 16513791
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB02201 - Malonate Ion
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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