AutismKB 2.0

Annotation Detail for SDHA


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Basic Information Top
Gene Symbol:SDHA ( FP,SDH1,SDH2,SDHF )
Gene Full Name: succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
Band: 5p15.33
Quick LinksEntrez ID:6389; OMIM: 600857; Uniprot ID:DHSA_HUMAN; ENSEMBL ID: ENSG00000073578; HGNC ID: 10680
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PWY-5690TCA cycle variation III (eukaryotic)
Pathway IDPathway Name
hsa00020Citrate cycle (TCA cycle)
hsa05016Huntington's disease
hsa05010Alzheimer's disease
hsa05012Parkinson's disease
hsa00190Oxidative phosphorylation
hsa01100Metabolic pathways
Pathway IDPathway Name
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncou
Pyruvate metabolism and Citric Acid (TCA) cycle
No data
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1934Cancer
No data
No data
Desease Name
Cardiomyopathy, dilated, 1GG
Mitochondrial respiratory chain complex II deficiency
Leigh syndrome
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of SDHA mRNAaffects expression 21346803
C015802 2,6-dichloro-4-nitrophenol 2,6-dichloro-4-nitrophenol results in decreased expression of SDHA mRNAdecreases expression 11227219
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of SDHA mRNAaffects expression 21346803
D000643 Ammonium Chloride Ammonium Chloride affects the expression of SDHA mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in decreased expression of SDHA mRNAdecreases expression 19422848
C006632 arsenic trioxide arsenic trioxide results in decreased expression of SDHA proteindecreases expression 19422848
C006632 arsenic trioxide arsenic trioxide results in increased expression of SDHA mRNAincreases expression 19422848
C006632 arsenic trioxide Ascorbic Acid inhibits the reaction [arsenic trioxide results in decreased expression of SDHA protein]decreases expression|decreases reaction 19422848
C006632 arsenic trioxide Taurine inhibits the reaction [arsenic trioxide results in decreased expression of SDHA protein]decreases expression|decreases reaction 19422848
D001205 Ascorbic Acid Ascorbic Acid inhibits the reaction [arsenic trioxide results in decreased expression of SDHA protein]decreases expression|decreases reaction 19422848
D002995 Clofibric Acid Clofibric Acid affects the expression of SDHA mRNAaffects expression 17602206
D003474 Curcumin Curcumin results in decreased expression of SDHA mRNAdecreases expression 17198877
D003687 Dehydroepiandrosterone Dehydroepiandrosterone results in increased expression of SDHA mRNAincreases expression 18709148
D004958 Estradiol Estradiol results in increased expression of SDHA mRNAincreases expression 18709148
17823450
D005419 Flavonoids Flavonoids results in increased expression of SDHA mRNAincreases expression 18035473
D005472 Fluorouracil SDHA protein affects the susceptibility to Fluorouracilaffects response to substance 15548681
D007657 Ketone Bodies Ketone Bodies results in increased expression of SDHA mRNAincreases expression 16807920
C023036 perfluorooctanoic acid perfluorooctanoic acid results in increased expression of SDHA mRNAincreases expression 18709148
C009277 sodium arsenate sodium arsenate results in increased expression of SDHA mRNAincreases expression 16882884
D013654 Taurine Taurine inhibits the reaction [arsenic trioxide results in decreased expression of SDHA protein]decreases expression|decreases reaction 19422848
D013853 Thioacetamide Thioacetamide results in decreased expression of SDHA mRNAdecreases expression 16297948
C066340 tolcapone tolcapone binds to SDHA proteinaffects binding 19783845
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 3.5218287403
MESH:D000230 Adenocarcinoma arsenic trioxide 7.0619825857 11798837
MESH:D000230 Adenocarcinoma Estradiol 7.0611473722
MESH:D000230 Adenocarcinoma Fluorouracil 7.0617638652
MESH:D000309 Adrenal Insufficiency Dehydroepiandrosterone 5.7217302879
MESH:D017109 Akathisia, Drug-Induced tolcapone 6.2611080934
MESH:D019973 Alcohol-Related Disorders Curcumin 5.0517887948
MESH:D000544 Alzheimer Disease Curcumin 4.6815590663
MESH:D000544 Alzheimer Disease tolcapone 4.6820150427
MESH:D000740 Anemia Fluorouracil 3.6717963324 15504547 16511603
MESH:D001172 Arthritis, Rheumatoid Curcumin 2.7316807698
MESH:D050197 Atherosclerosis Curcumin 3.2918704882
MESH:D001327 Autoimmune Diseases Curcumin 4.4519761891
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 9.2416206674
MESH:D001778 Blood Coagulation Disorders Thioacetamide 9.2419483382
MESH:D002545 Brain Ischemia Curcumin 4.2916770732
MESH:D001932 Brain Neoplasms Curcumin 3.9017596214
MESH:D001943 Breast Neoplasms Ascorbic Acid 2.0316443354
MESH:D001943 Breast Neoplasms Curcumin 2.0319250217 16243823 18593918 18462866
MESH:D001943 Breast Neoplasms Estradiol 2.0319861407 16675129 14630087 12948864 18497071 17261762 17289903 17018787
MESH:D001943 Breast Neoplasms Fluorouracil 2.0316595493 16557594 15136595 16110121 18608205 18357371 19217205
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.2911589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.4316111702
MESH:D002276 Carcinoid Tumor Fluorouracil 4.6416051944
MESH:D002277 Carcinoma Curcumin 8.4518593918
MESH:D002277 Carcinoma Fluorouracil 8.4517121937
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 11.3116705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 11.3116705839
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 11.3114691202 15073043 11135700 16217749 15553829
MESH:D006528 Carcinoma, Hepatocellular Estradiol 11.3116924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 11.3117971768 16332177 17088986 18930000 17045692 16799960
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 11.3117997003
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 2.9618414057
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.8519014326
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 3.0018695887
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.0812490120
MESH:D002294 Carcinoma, Squamous Cell Curcumin 4.8618462866
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 4.8616280240 16757204 17066447 18986760
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 6.566135515
MESH:D002471 Cell Transformation, Neoplastic Estradiol 6.5618566989
MESH:D018281 Cholangiocarcinoma Thioacetamide 4.2518291259
MESH:D003092 Colitis Curcumin 4.1416782535 18200517 16804969
MESH:D003103 Coloboma Curcumin 4.5118809619
MESH:D003110 Colonic Neoplasms Curcumin 3.9019359593 16340194
MESH:D003110 Colonic Neoplasms Fluorouracil 3.9018772588 17016597 15001691 17172411 16510598 17018589 17287894 17725105 17169374 16340194
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.5420501625
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.5417695437 18288408 16524972 15148649 20501625 17255274 18802399 16303861 16391804 18949393 18448328 16331619 14970324 17016601 15289873 18383874 17094418 18509181 17594712 17401013 16282729 17454858
MESH:D003139 Common Cold Ascorbic Acid 5.4517323712
MESH:D016510 Corneal Neovascularization Curcumin 4.8618497527
MESH:D023903 Coronary Restenosis arsenic trioxide 4.1412609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.0010525206
MESH:D019465 Craniofacial Abnormalities sodium arsenate 3.0010525206
MESH:D003490 Cyanosis 2,4-dinitrotoluene 10.7618551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 10.7618551238
MESH:D007644 Darier Disease Fluorouracil 4.7616733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.0515213294
MESH:D003866 Depressive Disorder tolcapone 4.2711224284 7768276
MESH:D003865 Depressive Disorder, Major tolcapone 4.8610440460
MESH:D003922 Diabetes Mellitus, Type 1 Dehydroepiandrosterone 3.6816616286
MESH:D003924 Diabetes Mellitus, Type 2 Ascorbic Acid 4.9016506275
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 4.9018403477
MESH:D058065 Diabetic Cardiomyopathies Taurine 6.0216025228
MESH:D003928 Diabetic Nephropathies Curcumin 8.9118204486
MESH:D003928 Diabetic Nephropathies Estradiol 8.9119279558
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 15.1421346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 15.1418551238 21346803
MESH:D056486 Drug-Induced Liver Injury sodium arsenate 15.1418186108
MESH:D056486 Drug-Induced Liver Injury Taurine 15.149328219
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 15.1412963478
MESH:D056486 Drug-Induced Liver Injury tolcapone 15.1419783845 16604736
MESH:D004381 Duodenal Ulcer Curcumin 4.0117351913
MESH:D004409 Dyskinesia, Drug-Induced tolcapone 5.3711455177
MESH:C538011 Eales disease Ascorbic Acid 5.459068938
MESH:D004487 Edema perfluorooctanoic acid 3.5412083418 17259670
MESH:D016889 Endometrial Neoplasms Estradiol 2.9519148513 18566989 11473722
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.5612903497
MESH:D004938 Esophageal Neoplasms Fluorouracil 4.5616785472 15173087 17638652 16481741 16337965
MESH:D054908 Extensively Drug-Resistant Tuberculosis tolcapone 5.9219578428
MESH:D005218 Fat Necrosis Thioacetamide 5.6916456712
MESH:D005234 Fatty Liver arsenic trioxide 7.9315073043
MESH:D005234 Fatty Liver Curcumin 7.9319297423
MESH:D005355 Fibrosis Curcumin 3.9518705752
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.2216904648
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.6518462866
MESH:D005909 Glioblastoma Curcumin 3.4517596214
MESH:D005910 Glioma Fluorouracil 2.8516145905
MESH:D018149 Glucose Intolerance sodium arsenate 5.0419446573
MESH:D006258 Head and Neck Neoplasms Curcumin 7.8718462866 18829502
MESH:D006258 Head and Neck Neoplasms Fluorouracil 7.8718337622 15162350 15102660
MESH:D006330 Heart Defects, Congenital Ascorbic Acid 3.7416080930
MESH:D006501 Hepatic Encephalopathy Thioacetamide 4.5315929193 17276928 18665440
MESH:D006505 Hepatitis Thioacetamide 4.1716456712
MESH:D006529 Hepatomegaly perfluorooctanoic acid 4.063609246
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 5.0017701891
MESH:D006548 Hernia, Diaphragmatic Ascorbic Acid 3.4616863852 16490937
MESH:D006558 Herpes Genitalis Estradiol 5.0015709030
MESH:D019584 Hot Flashes Estradiol 3.7217088409
MESH:D006930 Hyperalgesia perfluorooctanoic acid 3.8112083418
MESH:D006937 Hypercholesterolemia Curcumin 4.0118704882
MESH:D007249 Inflammation Curcumin 8.4118403477 16956363 17151092
MESH:D007249 Inflammation Flavonoids 8.4117296493
MESH:D007249 Inflammation perfluorooctanoic acid 8.4112083418
MESH:D015212 Inflammatory Bowel Diseases Curcumin 3.1918596194 18200517
MESH:D007333 Insulin Resistance Estradiol 2.9416627594 16393666
MESH:D007414 Intestinal Neoplasms Curcumin 4.1810783313
MESH:D007674 Kidney Diseases Estradiol 2.5615618244
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 17.4716705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 17.4716705839
MESH:D007680 Kidney Neoplasms Estradiol 17.4715610895
MESH:D007680 Kidney Neoplasms Fluorouracil 17.4716985049
MESH:D007888 Leigh Disease marker/mechanism
MESH:D007889 Leiomyoma Curcumin 4.5318555241
MESH:D007938 Leukemia arsenic trioxide 6.4415070760
MESH:D007938 Leukemia Curcumin 6.4418462866
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 9.6317077332 12560223
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 9.6316106398
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.2716972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.3914633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.7219077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1320471514 17050201 16467208 16968895 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.1819075265 16330433 16966277 12712474 16112521 12018890 15213294 17217047 16823087 19642359 17107899 16331271 9834237 15336539 19035177 12679006 17649720 15748426 19225113 17712046 11161223 16891316 15622746 11468182 17869043
MESH:D015458 Leukemia, T-Cell arsenic trioxide 11.5816882451
MESH:D015458 Leukemia, T-Cell Curcumin 11.5816106398
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 5.198812269
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 5.0517355460 18006644 18705752
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 5.0514659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Taurine 5.0515931870 15893842
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 5.0518032466 11481614 16248980 16489207 17629604 15362042 15078482 16097051 11172339 18416461 18031379 15465738 17127702 17355460 18458672 15075984 16098781 18380797 15158331 16511523 18295389 18606216 15288473 17292413 11682029 12557150 15474484 12085344 15334695 18615449 18263696 12175628 15095483 10677585 15316131 18395095 12679928 15288472 16126171 16343077 14739098 12891558 15716488 12531686 17050028
MESH:D008107 Liver Diseases Curcumin 4.4516956363
MESH:D008107 Liver Diseases Thioacetamide 4.4515158337 18374380 16337175
MESH:D017114 Liver Failure, Acute Thioacetamide 4.2715313186 15633222 12479984 17276928
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 17.807678174
MESH:D008113 Liver Neoplasms arsenic trioxide 17.8014682389
MESH:D008113 Liver Neoplasms Clofibric Acid 17.8017602206
MESH:D008113 Liver Neoplasms Dehydroepiandrosterone 17.8018709148
MESH:D008113 Liver Neoplasms Fluorouracil 17.8017045692 18383874 15113037 16603448
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 17.8014757943 18709148
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 14.016135515 2876786 2876784
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 14.0120377131
MESH:D008114 Liver Neoplasms, Experimental Ascorbic Acid 14.0118544905
MESH:D008114 Liver Neoplasms, Experimental Dehydroepiandrosterone 14.018603461
MESH:D008133 Long QT Syndrome arsenic trioxide 3.3115213294
MESH:D008171 Lung Diseases Ascorbic Acid 3.9216863852
MESH:D008175 Lung Neoplasms arsenic trioxide 4.9019825857 11798837
MESH:D008175 Lung Neoplasms Ascorbic Acid 4.9016401635
MESH:D008175 Lung Neoplasms Curcumin 4.9018462866 19359593 16243823
MESH:D008175 Lung Neoplasms Fluorouracil 4.9015246190
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.7615086387
MESH:D008223 Lymphoma Curcumin 3.5518462866
MESH:D016399 Lymphoma, T-Cell Curcumin 4.6516173963
MESH:D008325 Mammary Neoplasms, Experimental Dehydroepiandrosterone 6.3416457693
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 6.3417203775 16891317 11408345 11807958
MESH:D020149 Manganese Poisoning Estradiol 4.4519453300
MESH:D008545 Melanoma Curcumin 2.4118462866 17885582
MESH:D008569 Memory Disorders Curcumin 4.1117263510
OMIM:252011 MITOCHONDRIAL COMPLEX II DEFICIENCY marker/mechanism
MESH:D009062 Mouth Neoplasms Fluorouracil 3.6018986760 16757204
MESH:D009101 Multiple Myeloma arsenic trioxide 7.3315949261 19417148 11468182 14977855 19549372
MESH:D009101 Multiple Myeloma Curcumin 7.3319372569
MESH:D009134 Muscular Atrophy, Spinal Curcumin 4.8817962980
MESH:D009139 Musculoskeletal Abnormalities sodium arsenate 4.8118186108
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.6418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.1216105982 16882451
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.2416810080
MESH:D009336 Necrosis 2,4-dinitrotoluene 10.2318551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 10.237678174 18551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 10.1916624393
MESH:D009361 Neoplasm Invasiveness Curcumin 10.1918495463
MESH:D009369 Neoplasms Fluorouracil 2.5918239605 18600527 16928823
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 4.5012497104
MESH:D009389 Neovascularization, Pathologic Estradiol 3.7017289903
MESH:D009421 Nervous System Malformations Estradiol 3.6111399458 16427766
MESH:D009423 Nervous System Neoplasms Curcumin 5.6018462866
MESH:D009436 Neural Tube Defects arsenic trioxide 7.5410525206
MESH:D009436 Neural Tube Defects sodium arsenate 7.5410525206 19446573 11749123 18186108
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.4116436463
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 4.919802331
MESH:D009765 Obesity Ascorbic Acid 5.0517217161
MESH:D009765 Obesity Curcumin 5.0519297423
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 8.7516049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 8.7516049721
MESH:D010024 Osteoporosis Curcumin 3.4418719352
MESH:D015663 Osteoporosis, Postmenopausal Dehydroepiandrosterone 4.9916397352
MESH:D010051 Ovarian Neoplasms arsenic trioxide 7.8612452020 19769630 16624393
MESH:D010051 Ovarian Neoplasms Curcumin 7.8619020741 18462866
MESH:D010051 Ovarian Neoplasms Estradiol 7.8619401270
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 8.6215580305
MESH:D010190 Pancreatic Neoplasms Curcumin 8.6219401701 19196508 17440100
MESH:D010190 Pancreatic Neoplasms Fluorouracil 8.6216929163 16500647 15113037 19003803
MESH:D010235 Paraganglioma arsenic trioxide 4.1219927285
MESH:D010300 Parkinson Disease tolcapone 3.589305320 9708959 9591521 7566641 18328768 19783845 16758261 11793426 20334432 9333106 8635184 9754991 20216409 10651109 1977408 19578428 11586115 11432539 11746615 8739811 17089403
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 4.3617132714
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.8420887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.1119131511
MESH:D011471 Prostatic Neoplasms Curcumin 2.1111398177 10851300 12497104 18769126 18156803 18226269 15129424
MESH:D011471 Prostatic Neoplasms Estradiol 2.1116740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.1118626508 19082440
MESH:D011656 Pulmonary Emphysema Curcumin 4.4919168576
MESH:D011657 Pulmonary Eosinophilia Ascorbic Acid 5.3014606601
MESH:D012004 Rectal Neoplasms Fluorouracil 3.9716160472 18286688 18722050 15538739
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 3.9810666014 18379247
MESH:D012174 Retinitis Pigmentosa Ascorbic Acid 3.3016849425
MESH:D012509 Sarcoma Curcumin 4.0818462866
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.9216646077
MESH:D012640 Seizures 2,4-dinitrotoluene 5.7718551238
MESH:D012640 Seizures 2,6-dinitrotoluene 5.7718551238
MESH:D018805 Sepsis Curcumin 4.0418389075
MESH:D012871 Skin Diseases Ascorbic Acid 3.2018709164
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.5217007042
MESH:D013274 Stomach Neoplasms Fluorouracil 2.5218567086 18396642 17498489 19084572 16951190 17522103 19015929 16424979 17172411 15786421
MESH:D013276 Stomach Ulcer Ascorbic Acid 7.5518726076
MESH:D013276 Stomach Ulcer Curcumin 7.5519188055 16631530
MESH:D020521 Stroke Ascorbic Acid 4.2516403987 16517955
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.0519014326
MESH:D013978 Tibial Fractures Estradiol 4.6619048282
MESH:D014062 Tongue Neoplasms Fluorouracil 3.9516280240
MESH:D016171 Torsades de Pointes arsenic trioxide 3.9315213294
MESH:D018088 Tuberculosis, Multidrug-Resistant tolcapone 5.9219578428
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 11.8116049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 11.8116049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 11.8111780464 12973940 20435036 12845720
MESH:D001749 Urinary Bladder Neoplasms Curcumin 11.8118593936
MESH:D014565 Urogenital Neoplasms Curcumin 5.2318462866
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 11.8710091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 11.8710091137
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 3.8416803524
MESH:D014820 Vitiligo tolcapone 5.1510573327
Pathway ID Pathway Name
KEGG:05010 Alzheimer's disease
KEGG:00020 Citrate cycle (TCA cycle)
KEGG:05016 Huntington's disease
KEGG:01100 Metabolic pathways
KEGG:00190 Oxidative phosphorylation
KEGG:05012 Parkinson's disease
REACT:1046 Pyruvate metabolism and Citric Acid (TCA) cycle
REACT:6305 Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
REACT:33999 Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB00139 - Ubicoenzyme Anti-Ulcer Agents;Dietary supplement;Micronutrient;Radiation-Protective Agents
DB04141 - 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol
DB04657 - Carboxin Fungicides, Industrial
DB04795 - Thenoyltrifluoroacetone Chelating Agents
DB08689 - UBIQUINONE-1
No data
No data
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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