AutismKB 2.0

Annotation Detail for GALNT11


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Basic Information Top
Gene Symbol:GALNT11 ( FLJ21634,MGC71630 )
Gene Full Name: UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
Band: 7q36.1
Quick LinksEntrez ID:63917; OMIM: NA; Uniprot ID:GLT11_HUMAN; ENSEMBL ID: ENSG00000178234; HGNC ID: 19875
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa00512O-Glycan biosynthesis
hsa01100Metabolic pathways
No data
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of GALNT11 mRNAincreases expression 18648102
D016572 Cyclosporine Cyclosporine results in decreased expression of GALNT11 mRNAdecreases expression 20106945
D010634 Phenobarbital Phenobarbital results in increased expression of GALNT11 mRNAincreases expression 19270015
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of GALNT11 mRNAaffects binding|decreases expression|increases activity 19710929
D018038 Sodium Selenite Sodium Selenite results in increased expression of GALNT11 mRNAincreases expression 18175754
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 3.986195326
MESH:D055371 Acute Lung Injury pirinixic acid 3.5218653653
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.933712494
MESH:D018248 Adenoma, Liver Cell Phenobarbital 11.9817620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 11.9816434500
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.6311289319 1440618
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.5219483382
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 3.147296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 3.141701930 20935162 20007298 6705139 17173139
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.817296757
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 7.367505956
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 7.3612371664
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.744080065
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 14.939022650 19486331
MESH:D002779 Cholestasis Cyclosporine 14.9319486331
MESH:D002779 Cholestasis pirinixic acid 14.9319176532
MESH:D019457 Chromosome Breakage Sodium Selenite 5.2415894690
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 3.2811298694 12868966 18759878 11906362 2524372 8156756 14531868 8970840
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5618249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.892952479 3621924
MESH:D003920 Diabetes Mellitus Sodium Selenite 4.1016285004
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 4.2516192314 18289764 9328219 6679447 7440962 18692083 9022650 9653073 8291058 18648102 11289319 1440618 6482804
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 4.2515131321
MESH:D004421 Dystonia Phenobarbital 4.411851702
MESH:D004487 Edema pirinixic acid 2.8512083418
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.593659116
MESH:D004828 Epilepsies, Partial Phenobarbital 4.483922381 11558140
MESH:D004827 Epilepsy Phenobarbital 3.0420417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.876401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.747750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 4.563659116
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.173581430
MESH:D005234 Fatty Liver Cyclosporine 8.8219224547
MESH:D005234 Fatty Liver pirinixic acid 8.8220131406 19236843
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.636705139
MESH:D005355 Fibrosis Cyclosporine 3.6212639820 12168785
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.768708960
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.447505956
MESH:D006333 Heart Failure pirinixic acid 2.7320558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.9615720958
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.956705139
MESH:D006529 Hepatomegaly Phenobarbital 10.1416109766
MESH:D006529 Hepatomegaly pirinixic acid 10.1416221962 19176532 18467677 19772884
MESH:D006943 Hyperglycemia pirinixic acid 3.5320558911
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.4215034207
MESH:D006973 Hypertension Cyclosporine 2.2010903974
MESH:D007333 Insulin Resistance pirinixic acid 8.0416306350
MESH:D007333 Insulin Resistance Sodium Selenite 8.0414714311
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.638074119 9022650
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.0515604871
MESH:D007674 Kidney Diseases Cyclosporine 2.528314463 10903974 18776723
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 8.306582329
MESH:D007680 Kidney Neoplasms Cyclosporine 8.3012371664
MESH:D008103 Liver Cirrhosis Phenobarbital 3.0721047994
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.409327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008107 Liver Diseases Phenobarbital 2.2319363144
MESH:D008113 Liver Neoplasms Phenobarbital 4.8315975961 8742319 19482888 19073162 19812893 21047994
MESH:D008113 Liver Neoplasms pirinixic acid 4.8320007298 16377806 15890375
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 6.631399818 598648 3712494 6587162
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 6.6318308698 17172636 6150874 1399818 2563599
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.4614737004
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.4016801185
MESH:D009135 Muscular Diseases pirinixic acid 3.9916239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2619151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.2216411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 5.0217484760
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.583581430
MESH:D009369 Neoplasms pirinixic acid 2.0917405874
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.0517954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.6119348381 18481113
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 3.136679447
MESH:D009765 Obesity pirinixic acid 1.8820558911
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.776482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.633988306
MESH:D010018 Osteomalacia Phenobarbital 4.9017016548
MESH:D010190 Pancreatic Neoplasms Phenobarbital 2.5916965848
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.977296757
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 5.086228378
MESH:D011230 Precancerous Conditions Cyclosporine 10.0712371664
MESH:D011230 Precancerous Conditions Phenobarbital 10.072563599
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.3418760546
MESH:D019310 Pseudolymphoma Phenobarbital 5.1112752131
MESH:D011565 Psoriasis Cyclosporine 2.3216882103
MESH:D015427 Reperfusion Injury pirinixic acid 2.5319058328
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.643692021
MESH:D012640 Seizures Phenobarbital 2.923137016 16876388 11442880 4039156
MESH:D003294 Seizures, Febrile Phenobarbital 5.366407741
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 8.063712494 6587162 1399818 6582329 7505956
MESH:D013964 Thyroid Neoplasms Phenobarbital 8.061399818
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 2.398074119
MESH:D014605 Uveitis Cyclosporine 4.591336536
MESH:D014985 Xerophthalmia Cyclosporine 5.0517120751
Pathway ID Pathway Name
KEGG:01100 Metabolic pathways
KEGG:00512 Mucin type O-Glycan biosynthesis
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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