AutismKB 2.0

Annotation Detail for NEUROD6


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Basic Information Top
Gene Symbol:NEUROD6 ( Atoh2,MATH2,Math-2,NEX1M,bHLHa2 )
Gene Full Name: neurogenic differentiation 6
Band: 7p14.3
Quick LinksEntrez ID:63974; OMIM: 611513; Uniprot ID:NDF6_HUMAN; ENSEMBL ID: ENSG00000164600; HGNC ID: 13804
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D008070 Lipopolysaccharides Lipopolysaccharides results in decreased expression of NEUROD6 mRNAdecreases expression 12057914
D009151 Mustard Gas Mustard Gas results in increased expression of NEUROD6 mRNAincreases expression 15674843
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin affects the expression of NEUROD6 mRNAaffects expression 16962184
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of NEUROD6 mRNAincreases expression 16922920
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.5914514962 15322242 11752688
MESH:D055371 Acute Lung Injury Lipopolysaccharides 4.5618653653 11850527
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 4.1216835633
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.3911748828
MESH:D001249 Asthma Mustard Gas 2.8110378619
MESH:D001768 Blister Mustard Gas 5.9019167455
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.5312125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.6615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 3.0215746008
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.6620435547
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 5.9015286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 5.8410378619 17687719
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 3.1616835633
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.5818670907 18850075 16120746
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.5816835633
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.2516354765 8697196 15340226 12621046 15668235
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.4814669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2710048152 20055451 15322242
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.7417107852
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 1.6220420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 3.0911462148
MESH:D004487 Edema Mustard Gas 8.4811402378 9260866 11428631 11428647
MESH:D004487 Edema Tetrachlorodibenzodioxin 8.4812711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.7715322242 18230668 16714409
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.479294722 10568697
MESH:D019446 Endotoxemia Lipopolysaccharides 5.1417637181 15821434 15328337
MESH:D004890 Erythema Mustard Gas 5.909357497
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.3411564622
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 4.1111858732
MESH:D005334 Fever Lipopolysaccharides 4.469205823 11852909
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 3.6020067830
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 5.4610696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.5310048152 11294989
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.8316366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.8211000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.5416120746 12621046 15340226
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.9116959395 15340226 18606429 8697196 16354765
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 2.0318850075 18670907
MESH:D007249 Inflammation Lipopolysaccharides 9.589205823 17963957 17255318 12878042 17237260
MESH:D007249 Inflammation Mustard Gas 9.589357497 11428620 16001271 17524151 11428631 11402378 11428647 9260866 8975870
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 9.5812200463 12878042
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 5.1617255318
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.8216580747
MESH:D007970 Leukopenia Lipopolysaccharides 5.4415821434
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 2.5712878042
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 2.5712878042
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 1.8416984957
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 2.3512151625
MESH:D008171 Lung Diseases Mustard Gas 3.7318702808 18161513
MESH:D055370 Lung Injury Lipopolysaccharides 4.6621114838
MESH:D008175 Lung Neoplasms Mustard Gas 2.503148597 8781369
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 2.5019555203 11884234
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.3812213967
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.8014600291
MESH:D009503 Neutropenia Mustard Gas 4.507688884 16761898
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 5.1212520081
MESH:D011014 Pneumonia Lipopolysaccharides 5.3012224865 11605937
MESH:D011041 Poisoning Mustard Gas 4.3215727166
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 4.1418163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.9311896295 11222880 11399792 11118676
MESH:D011537 Pruritus Mustard Gas 4.8318058305
MESH:D011658 Pulmonary Fibrosis Mustard Gas 3.0617720292 17266442 17620002 17894541 10334151
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 4.0010835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.4218990726
MESH:D012871 Skin Diseases Mustard Gas 2.8016961503 15451306 12880345
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.2116192470
MESH:D013921 Thrombocytopenia Lipopolysaccharides 4.6115821434
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.7712697716
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 5.4612125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 5.1215886252
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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