AutismKB 2.0

Annotation Detail for SELL


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SELL ( CD62L,LAM1,LECAM1,LEU8,LNHR,LSEL,LYAM1,PLNHR,TQ1 )
Gene Full Name: selectin L
Band: 1q24.2
Quick LinksEntrez ID:6402; OMIM: 153240; Uniprot ID:LYAM1_HUMAN; ENSEMBL ID: ENSG00000188404; HGNC ID: 10720
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04514Cell adhesion molecules (CAMs)
Pathway IDPathway Name
Hemostasis
Signaling in Immune system
No data
No data
Pathway IDPathway Name
500477Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1723Brucellosis
1772Peptic ulcer
1786Neck cancer
1793Infection by cryptococcus neoformans
1809HIV infection
1869Behcet syndrome
1904Diabetes mellitus
1918Atherosclerosis
1841Stomach cancer
2038Gastritis
2044Pre-Eclampsia
2051Leukemia
2053Colon cancer
1925Pemphigoid, Bullous
2083IGA glomerulonephritis
2146Lupus erythematosus
2156Pseudoxanthoma elasticum
2161Hodgkin's disease
Desease Name
Kidney Failure, Chronic
RENAL
brucellosis
Amyotrophic Lateral Sclerosis
IMMUNE
NEUROLOGICAL
Graves' disease
METABOLIC
diabetes, type 2
INFECTION
Desease Name
Amyotrophic lateral sclerosis
Desease Name
IgA nephropathy susceptibility to
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016601 4-hydroxytamoxifen 4-hydroxytamoxifen results in increased expression of SELL mRNAincreases expression 19901195
D000117 Acetylglucosamine [Acetylglucosamine analog binds to Biotin] which binds to SELL proteinaffects binding 12191509
D000117 Acetylglucosamine Acetylglucosamine analog binds to SELL proteinaffects binding 12191509
D000255 Adenosine Triphosphate P2RX7 protein affects the reaction [Adenosine Triphosphate results in increased secretion of SELL protein]affects reaction|increases secretion 11003599
D000643 Ammonium Chloride Ammonium Chloride affects the expression of SELL mRNAaffects expression 16483693
D001710 Biotin [Acetylglucosamine analog binds to Biotin] which binds to SELL proteinaffects binding 12191509
D019819 Budesonide Budesonide inhibits the reaction [lipopolysaccharide, Escherichia coli 0111 B4 results in increased expression of SELL mRNA]decreases reaction|increases expression 15734790
D002084 Butylated Hydroxytoluene Butylated Hydroxytoluene results in decreased expression of SELL mRNAdecreases expression 19925653
D016572 Cyclosporine Cyclosporine results in decreased expression of SELL mRNAdecreases expression 20106945
C014347 decitabine decitabine results in increased expression of SELL mRNAincreases expression 19194470
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of SELL mRNAaffects cotreatment|increases expression 19619570
D004958 Estradiol Estradiol results in increased expression of SELL mRNAincreases expression 19619570
D005419 Flavonoids Flavonoids results in increased expression of SELL mRNAincreases expression 15465739
D005419 Flavonoids Flavonoids results in decreased expression of SELL mRNAdecreases expression 18035473
D016285 Iloprost Iloprost results in decreased expression of SELL proteindecreases expression 16363279
D007213 Indomethacin Indomethacin results in decreased expression of SELL proteindecreases expression 11980903
C440499 lipopolysaccharide, Escherichia coli 0111 B4 Budesonide inhibits the reaction [lipopolysaccharide, Escherichia coli 0111 B4 results in increased expression of SELL mRNA]decreases reaction|increases expression 15734790
C440499 lipopolysaccharide, Escherichia coli 0111 B4 lipopolysaccharide, Escherichia coli 0111 B4 results in increased expression of SELL mRNAincreases expression 15734790
C440499 lipopolysaccharide, Escherichia coli 0111 B4 resveratrol affects the reaction [lipopolysaccharide, Escherichia coli 0111 B4 results in increased expression of SELL mRNA]affects reaction|increases expression 15734790
D008070 Lipopolysaccharides Lipopolysaccharides results in decreased expression of SELL proteindecreases expression 12734376
C056709 N,N-diacetylcystine N,N-diacetylcystine results in decreased expression of SELL proteindecreases expression 17157857
D010126 Ozone Ozone results in increased expression of SELL mRNAincreases expression 16330353
D010936 Plant Extracts Plant Extracts results in increased expression of SELL mRNAincreases expression 15465739
C025299 polyphenols polyphenols results in increased expression of SELL mRNAincreases expression 15465739
C025299 polyphenols polyphenols results in decreased expression of SELL mRNAdecreases expression 16293270
C059514 resveratrol resveratrol affects the reaction [lipopolysaccharide, Escherichia coli 0111 B4 results in increased expression of SELL mRNA]affects reaction|increases expression 15734790
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of SELL mRNAaffects cotreatment|increases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of SELL mRNAincreases expression 19901195
19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of SELL proteindecreases expression 18684927
15310856
D013792 Thalidomide Thalidomide results in decreased expression of SELL proteindecreases expression 16344495
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.2714514962 15322242 11752688
MESH:D000014 Abnormalities, Drug-Induced Thalidomide 8.278333272
MESH:D000138 Acidosis Ammonium Chloride 3.4318287403
MESH:D058186 Acute Kidney Injury resveratrol 3.7316538975
MESH:D055371 Acute Lung Injury Lipopolysaccharides 3.9111850527 18653653
MESH:D000230 Adenocarcinoma Estradiol 4.4711473722
MESH:D000230 Adenocarcinoma Indomethacin 4.4716537180
MESH:D000236 Adenoma Indomethacin 6.8511497255
MESH:D000236 Adenoma resveratrol 6.8515688382
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.2516835633
MESH:D016301 Alveolar Bone Loss Indomethacin 5.2417225004
MESH:D000544 Alzheimer Disease Indomethacin 9.2817627676 15579461
MESH:D000544 Alzheimer Disease Ozone 9.2815513908
MESH:D000544 Alzheimer Disease Plant Extracts 9.2816962711
MESH:D000544 Alzheimer Disease resveratrol 9.2816183991 16162502
MESH:D000690 Amyotrophic Lateral Sclerosis Thalidomide 4.2716510725
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8311748828
MESH:D001014 Aortic Aneurysm Indomethacin 4.7210231640
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 4.7410388637
MESH:D018771 Arthralgia Indomethacin 5.042160914
MESH:D001169 Arthritis, Experimental Plant Extracts 12.1414686799
MESH:D001169 Arthritis, Experimental resveratrol 12.1417115116
MESH:D001169 Arthritis, Experimental Thalidomide 12.149598899
MESH:D001172 Arthritis, Rheumatoid Indomethacin 4.7711248219
MESH:D001172 Arthritis, Rheumatoid Ozone 4.7715570426
MESH:D001249 Asthma Budesonide 5.4315136378 10893010 12604023 18489783 20004779 12113382 15572850
MESH:D001249 Asthma Ozone 5.4316373670 17854713
MESH:D050197 Atherosclerosis resveratrol 3.2017967414 16873680
MESH:D001477 Bartter Syndrome Indomethacin 4.8510684365
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 2.9212125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6815746008
MESH:D001929 Brain Edema Indomethacin 4.9011481608
MESH:D002545 Brain Ischemia Indomethacin 16.4012524144
MESH:D002545 Brain Ischemia Plant Extracts 16.4016041641
MESH:D002545 Brain Ischemia resveratrol 16.4017600658
MESH:D001943 Breast Neoplasms decitabine 2.3118320071 19208741
MESH:D001943 Breast Neoplasms Estradiol 2.3112948864 19861407 16675129 17261762 18497071 17018787 17289903 14630087
MESH:D001943 Breast Neoplasms Indomethacin 2.3117401462
MESH:D001943 Breast Neoplasms resveratrol 2.3117534123 17651959 16393696
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.3120435547
MESH:D016535 Bronchial Hyperreactivity Ozone 3.5718417511 15516495 17626835 18315731 16777450 19059883 14754758
MESH:D002056 Burns Indomethacin 4.5710459503
MESH:D002057 Burns, Chemical Plant Extracts 5.219625245
MESH:D002100 Cachexia Indomethacin 11.9615141370 11239499 15625704 16537180
MESH:D002100 Cachexia Ozone 11.9616183385
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.3316111702
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6916835633
MESH:D006528 Carcinoma, Hepatocellular Estradiol 8.7016924424
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 8.7016391822
MESH:D006528 Carcinoma, Hepatocellular Plant Extracts 8.7018834353
MESH:D006528 Carcinoma, Hepatocellular resveratrol 8.7016227395 19321006
MESH:D006528 Carcinoma, Hepatocellular Thalidomide 8.7016313753
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 10.9911053908
MESH:D018827 Carcinoma, Lewis Lung resveratrol 10.9916675471
MESH:D018276 Carcinoma, Medullary Indomethacin 5.2214736730 18791128 11352223
MESH:D002292 Carcinoma, Renal Cell Indomethacin 3.3117341418
MESH:D002294 Carcinoma, Squamous Cell decitabine 7.4819215824
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 7.4815482327 12636206
MESH:D002294 Carcinoma, Squamous Cell resveratrol 7.4816227395
MESH:D006332 Cardiomegaly Plant Extracts 6.7417645561
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.7418670907 16120746 18850075
MESH:D002318 Cardiovascular Diseases resveratrol 3.3815458977
MESH:D002386 Cataract Adenosine Triphosphate 4.5315003327
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 6.2712371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 6.2718566989
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 9.3916835633
MESH:D018281 Cholangiocarcinoma Thalidomide 9.3918291259
MESH:D002764 Cholecystitis Indomethacin 5.0411181007
MESH:D002779 Cholestasis Cyclosporine 2.8219486331
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0515340226 16354765 8697196 12621046 15668235
MESH:D003092 Colitis resveratrol 9.6116474422
MESH:D003092 Colitis Thalidomide 9.6116680017
MESH:D003110 Colonic Neoplasms decitabine 8.1817616700
MESH:D003110 Colonic Neoplasms Indomethacin 8.1815936596 15637740 15786552 15963497 15625704 11260862
MESH:D003110 Colonic Neoplasms polyphenols 8.1816293270
MESH:D003110 Colonic Neoplasms resveratrol 8.1816338953
MESH:D015179 Colorectal Neoplasms decitabine 3.5018981723
MESH:D015179 Colorectal Neoplasms Indomethacin 3.5012606626 18059344 11197048 17054584
MESH:D015179 Colorectal Neoplasms resveratrol 3.5016550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9517141729 14669216
MESH:D016510 Corneal Neovascularization Thalidomide 5.449301478
MESH:D003327 Coronary Disease resveratrol 3.6716507316
MESH:D018352 Coronavirus Infections Indomethacin 5.5917302372
MESH:D003389 Cranial Nerve Diseases Thalidomide 6.189200351
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.8315322242 20055451 10048152
MESH:D019465 Craniofacial Abnormalities Thalidomide 2.839200351
MESH:D003424 Crohn Disease Thalidomide 4.1016078585
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.6616873680
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6417107852
MESH:D003928 Diabetic Nephropathies Estradiol 14.5019279558
MESH:D003928 Diabetic Nephropathies Plant Extracts 14.5019706694
MESH:D003928 Diabetic Nephropathies resveratrol 14.5016286809
MESH:D003967 Diarrhea Indomethacin 3.677237001 7907874
MESH:D056486 Drug-Induced Liver Injury polyphenols 3.8619370779
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.8620420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6611462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 5.0218446180 12774134 17190690 18043480 16133044 16326151
MESH:D004381 Duodenal Ulcer Indomethacin 4.0117329845 11595431 11595415 17202747 17351913 10671773 17045617 16699067 17151854 11535926 11991626
MESH:D004417 Dyspnea Budesonide 5.4120016425
MESH:D004487 Edema Indomethacin 15.5416100529 7990266 7907874 10653021 19703484 8273558 8985016
MESH:D004487 Edema Plant Extracts 15.5412787963
MESH:D004487 Edema resveratrol 15.548985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 15.5412711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.7718230668 15322242 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 3.9017872969
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.9919294695
MESH:D016889 Endometrial Neoplasms 4-hydroxytamoxifen 7.5019148513
MESH:D016889 Endometrial Neoplasms Estradiol 7.5019148513 18566989 11473722
MESH:D004715 Endometriosis Indomethacin 8.6815652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 8.6810568697 9294722
MESH:D004719 Endomyocardial Fibrosis Plant Extracts 5.5515268973
MESH:D019446 Endotoxemia Indomethacin 17.0218509659
MESH:D019446 Endotoxemia lipopolysaccharide, Escherichia coli 0111 B4 17.0212954792
MESH:D019446 Endotoxemia Lipopolysaccharides 17.0215821434 17637181 15328337
MESH:D004751 Enteritis Indomethacin 4.6210567023 16328016 17763956
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 11.9417980183
MESH:D020345 Enterocolitis, Necrotizing resveratrol 11.9417923197
MESH:D004802 Eosinophilia Indomethacin 3.9211298111
MESH:D004827 Epilepsy Plant Extracts 3.6619439326 19700373
MESH:D004938 Esophageal Neoplasms Indomethacin 2.7711005569
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9111564622
MESH:D005234 Fatty Liver Cyclosporine 7.6519224547
MESH:D005234 Fatty Liver Plant Extracts 7.6515975614
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3311858732
MESH:D005334 Fever Indomethacin 14.8011852909 17627676 10431976
MESH:D005334 Fever lipopolysaccharide, Escherichia coli 0111 B4 14.8016997862
MESH:D005334 Fever Lipopolysaccharides 14.8011852909 9205823
MESH:D005354 Fibrosarcoma Indomethacin 4.7610962813
MESH:D005355 Fibrosis Cyclosporine 14.0412639820 12168785
MESH:D005355 Fibrosis Indomethacin 14.0417994277
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 14.0420067830
MESH:D005499 Folliculitis Indomethacin 5.0411298111
MESH:D005739 Gas Poisoning Budesonide 5.8020016425
MESH:D005756 Gastritis Indomethacin 4.6215046732
MESH:D005871 Giant Lymph Node Hyperplasia Thalidomide 6.1812701121
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.098708960
MESH:D005909 Glioblastoma Indomethacin 3.4812870263
MESH:D005910 Glioma Indomethacin 6.4316487511 18371953
MESH:D005910 Glioma Thalidomide 6.4316327979
MESH:D005922 Glomerulonephritis, IGA marker/mechanism
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 4.1811849393
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4710696789
MESH:D006073 Gout Indomethacin 5.2211248219
MESH:D006258 Head and Neck Neoplasms decitabine 7.7419215824
MESH:D006258 Head and Neck Neoplasms Indomethacin 7.7415482327
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.2610048152 11294989
MESH:D006333 Heart Failure Plant Extracts 3.7918097624
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.2915720958
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.2716366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2111000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 4.4515633222
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.5515135802
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.7615340226 12621046 16120746
MESH:D006558 Herpes Genitalis Estradiol 4.9015709030
MESH:D006561 Herpes Simplex Plant Extracts 9.6810715843
MESH:D006561 Herpes Simplex resveratrol 9.6816876885
MESH:D015658 HIV Infections Plant Extracts 3.6112878215
MESH:D019584 Hot Flashes Estradiol 9.9017088409
MESH:D019584 Hot Flashes Plant Extracts 9.9014716179 16566672 17454163
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.9216354765 15340226 8697196 16959395 18606429
MESH:D006930 Hyperalgesia Indomethacin 3.6712727271
MESH:D034321 Hyperamylasemia Indomethacin 5.5917883296
MESH:D006937 Hypercholesterolemia resveratrol 3.8917188708
MESH:D006940 Hyperemia Indomethacin 4.8712524144
MESH:D020138 Hyperhomocysteinemia Plant Extracts 4.3516484555
MESH:D006949 Hyperlipidemias Indomethacin 14.9117546600
MESH:D006949 Hyperlipidemias Plant Extracts 14.9115975614 15268973
MESH:D006949 Hyperlipidemias resveratrol 14.9116873680
MESH:D006967 Hypersensitivity Butylated Hydroxytoluene 4.3917604070
MESH:D006973 Hypertension Cyclosporine 4.7810903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.7818850075 18670907
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.1917488730
MESH:D007077 Ileal Diseases Indomethacin 4.9010574470 18306037
MESH:D007079 Ileitis Indomethacin 5.2210647630 16133968 10651667
MESH:D007235 Infant, Premature, Diseases Indomethacin 5.2416133044
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.5217600658
MESH:D007248 Infertility, Male decitabine 3.1217581917
MESH:D007249 Inflammation Flavonoids 27.5317296493
MESH:D007249 Inflammation Indomethacin 27.537812673 12568917 3291741
MESH:D007249 Inflammation Lipopolysaccharides 27.5312878042 17255318 9205823 17237260 17963957
MESH:D007249 Inflammation Plant Extracts 27.5316366677 15997105 19332304 12787963
MESH:D007249 Inflammation polyphenols 27.5316366677
MESH:D007249 Inflammation resveratrol 27.5316366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 27.5312878042 12200463
MESH:D007249 Inflammation Thalidomide 27.5316134734
MESH:D007251 Influenza, Human resveratrol 4.4216624496
MESH:D007333 Insulin Resistance Estradiol 2.8816627594 16393666
MESH:D007410 Intestinal Diseases Indomethacin 4.2015831440 17329856 11686837 11855677 11713966 18236018 10210152 15610444 17994277
MESH:D007414 Intestinal Neoplasms Plant Extracts 4.5012351151 12584176 12628509
MESH:D019586 Intracranial Hypertension Indomethacin 5.2415241188
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.5117255318
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2116580747
MESH:D007579 Jejunal Diseases Indomethacin 4.9018306037 10574470 16133968
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.3115604871
MESH:D007674 Kidney Diseases Cyclosporine 9.688314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 9.6815618244
MESH:D007674 Kidney Diseases Indomethacin 9.6817190690
MESH:D007680 Kidney Neoplasms Cyclosporine 6.9212371664
MESH:D007680 Kidney Neoplasms Estradiol 6.9215610895
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.8010320625 12228301 11703811
MESH:D007898 Leishmaniasis, Visceral Thalidomide 4.2416514283
MESH:D007938 Leukemia decitabine 3.0118980019 19235587
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 3.8315631656 16572323 10785260
MESH:D007951 Leukemia, Myeloid decitabine 3.8818454857 17236224 19117987
MESH:D015470 Leukemia, Myeloid, Acute decitabine 6.2317679729 18206229 18460780 18704418 19010910 19387464
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 6.2318360721
MESH:D015470 Leukemia, Myeloid, Acute Thalidomide 6.2318720364
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.3318055864
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 3.4916087638
MESH:D007964 Leukocytosis Indomethacin 5.2416537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.5917980183
MESH:D007970 Leukopenia Lipopolysaccharides 4.5715821434
MESH:D017880 Limb Deformities, Congenital Thalidomide 4.3610473037
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.5911479899
MESH:D008103 Liver Cirrhosis Plant Extracts 7.1517157831
MESH:D008103 Liver Cirrhosis Thalidomide 7.1517174718 16943688
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 8.5514716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 8.5518194892
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 8.5512878042
MESH:D008106 Liver Cirrhosis, Experimental Plant Extracts 8.5515479170
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 8.5512878042
MESH:D008106 Liver Cirrhosis, Experimental Thalidomide 8.5515465738
MESH:D008107 Liver Diseases Plant Extracts 4.5517034775
MESH:D008107 Liver Diseases polyphenols 4.5516698588
MESH:D008113 Liver Neoplasms Butylated Hydroxytoluene 10.4118177683
MESH:D008113 Liver Neoplasms Plant Extracts 10.4119168119
MESH:D008113 Liver Neoplasms resveratrol 10.4119812893 19073162 19321006 20405173
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 10.4116984957
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 2.0312151625
MESH:D008171 Lung Diseases Ozone 3.298266340 19066396
MESH:D055370 Lung Injury Lipopolysaccharides 8.8121114838
MESH:D055370 Lung Injury Ozone 8.8120417186
MESH:D008175 Lung Neoplasms Budesonide 8.3717163412 16885199 12117777
MESH:D008175 Lung Neoplasms Butylated Hydroxytoluene 8.3711696405 16337739 19359593 11246140 19925653 15390079 18597497
MESH:D008175 Lung Neoplasms Indomethacin 8.3711497255 16537180 11053908
MESH:D008175 Lung Neoplasms Ozone 8.377614698 8597069
MESH:D008175 Lung Neoplasms Plant Extracts 8.3720869020
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 8.3711884234 19555203
MESH:D008223 Lymphoma decitabine 3.3319470736
MESH:D016393 Lymphoma, B-Cell resveratrol 4.1717088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.7614749477
MESH:D015674 Mammary Neoplasms, Animal resveratrol 4.1215688416
MESH:D008325 Mammary Neoplasms, Experimental Butylated Hydroxytoluene 9.671500032
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 9.6716891317 11807958 11408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 9.6711606380 8985016
MESH:D020149 Manganese Poisoning Estradiol 4.3519453300
MESH:D008545 Melanoma decitabine 5.2116505122 17785578
MESH:D008545 Melanoma resveratrol 5.2117992120
MESH:D008545 Melanoma Thalidomide 5.2112829675 17089043 16098027
MESH:D008659 Metabolic Diseases resveratrol 4.2617112576
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.6616801185
MESH:D008679 Metaplasia Ozone 4.9810496685
MESH:D008881 Migraine Disorders Indomethacin 3.5811903285
MESH:D009062 Mouth Neoplasms Indomethacin 3.8912636206
MESH:D009101 Multiple Myeloma decitabine 11.7918172295
MESH:D009101 Multiple Myeloma resveratrol 11.7917164350 14749477 16267019 16490592 17935668 17049120
MESH:D009101 Multiple Myeloma Thalidomide 11.7915741222 19112201 15920492 17168659 15744524 19112817 15867202 16445831 19372569 15939924
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.7417962980
MESH:D009190 Myelodysplastic Syndromes decitabine 7.6519010910 16882708 18608210 19157545
MESH:D009190 Myelodysplastic Syndromes Thalidomide 7.6518720364
MESH:D009203 Myocardial Infarction resveratrol 2.9817015251 16317513 16456233 17188708 17125593 16525036
MESH:D017202 Myocardial Ischemia resveratrol 8.6617125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 8.6612213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.1816810080
MESH:D009205 Myocarditis resveratrol 4.6317322642
MESH:D009362 Neoplasm Metastasis Indomethacin 3.1216537180 11239499 11053908
MESH:D009369 Neoplasms decitabine 2.6517925555 19470736 19116145
MESH:D009374 Neoplasms, Experimental Indomethacin 8.9710663608 15625704
MESH:D009374 Neoplasms, Experimental resveratrol 8.978985016
MESH:D009389 Neovascularization, Pathologic Estradiol 3.6017289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.3117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.1719348381 18481113
MESH:D009421 Nervous System Malformations Estradiol 15.7511399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 15.7514600291
MESH:D009421 Nervous System Malformations Thalidomide 15.7516859833
MESH:D019954 Neurobehavioral Manifestations Plant Extracts 5.0517168769
MESH:D019636 Neurodegenerative Diseases Indomethacin 8.3912349958
MESH:D019636 Neurodegenerative Diseases resveratrol 8.3917652729
MESH:D020078 Neurogenic Inflammation resveratrol 4.2717929310
MESH:D009765 Obesity Plant Extracts 3.1120132043 19056576
MESH:D007752 Obstetric Labor, Premature Indomethacin 5.046374098
MESH:D010003 Osteoarthritis Indomethacin 3.597009135
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 4.1317513867
MESH:D010051 Ovarian Neoplasms decitabine 7.8219331143 19259094
MESH:D010051 Ovarian Neoplasms Estradiol 7.8219401270
MESH:D010051 Ovarian Neoplasms Thalidomide 7.8216288038
MESH:D010146 Pain Indomethacin 3.3617440234 3291741 17627676 13679232
MESH:D010149 Pain, Postoperative Indomethacin 4.5512538197 18702446
MESH:D010190 Pancreatic Neoplasms decitabine 2.7219294695
MESH:D010195 Pancreatitis Indomethacin 3.8015028970 17883296
MESH:D010212 Papilloma Plant Extracts 4.3616517061 15173996
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.5916537180
MESH:D010291 Paresis Thalidomide 6.189200351
MESH:D020734 Parkinsonian Disorders Indomethacin 4.0012349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.5911903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1212520081
MESH:D010437 Peptic Ulcer Indomethacin 5.0211148446
MESH:D010518 Periodontitis Indomethacin 4.7817225004
MESH:D010538 Peritonitis Ozone 4.0016369182
MESH:D011014 Pneumonia Butylated Hydroxytoluene 17.9111893704
MESH:D011014 Pneumonia Lipopolysaccharides 17.9112224865 11605937
MESH:D011014 Pneumonia Ozone 17.9118007984 18929643 18381685
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4318163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.1112371664
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Thalidomide 4.1617031469
MESH:D011225 Pre-Eclampsia Iloprost 5.6210329876
MESH:D047928 Premature Birth Indomethacin 5.0017000239
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 9.1616679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.1611222880 11896295 11399792 11118676
MESH:D055728 Primary Myelofibrosis decitabine 4.6017616702
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.7620887781
MESH:D011471 Prostatic Neoplasms Estradiol 2.2016740699
MESH:D011471 Prostatic Neoplasms Plant Extracts 2.2017804756 14666653
MESH:D011471 Prostatic Neoplasms resveratrol 2.2016731767 17804756 17675339 17718901 17636462 15767336
MESH:D011471 Prostatic Neoplasms Thalidomide 2.2016729912
MESH:D011507 Proteinuria Indomethacin 4.0411849393
MESH:D011536 Prurigo Thalidomide 6.1812755975
MESH:D011565 Psoriasis Cyclosporine 2.1816882103
MESH:D011928 Raynaud Disease Iloprost 6.4616363279
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.4516325855
MESH:D015427 Reperfusion Injury resveratrol 3.2117058453 16314181 17520802 15827377 16317513
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.6510835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7118990726
MESH:D012208 Rhabdomyosarcoma decitabine 4.2819155313
MESH:D019873 Schnitzler Syndrome Thalidomide 5.8116096327
MESH:D012878 Skin Neoplasms Plant Extracts 9.2415173996 16517061
MESH:D012878 Skin Neoplasms resveratrol 9.248985016 15837718
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.2416192470
MESH:D013272 Stomach Diseases Indomethacin 4.2915472012 18545984 16280098 16184426 17207306 17160473 15038085 17638125 10215738 16113693 10192188 18209964 10486359
MESH:D013274 Stomach Neoplasms decitabine 2.7219037991
MESH:D013274 Stomach Neoplasms Indomethacin 2.7215609394
MESH:D013276 Stomach Ulcer Indomethacin 11.6516169175 11595415 16934674 15255614 16397915 18193104 17918041 12500499 17895592 18299717 18181030 16252198 12787963 11729361 11595431 18237397 18726076 11523592 17627676 16150113 10750652 11145282 16755016 17657623 17135157 18087811 18431645 12498302 1323529 14567935 16631530 15104355 10423059 12467913 18209962 17977527 10878458 17654042 11906479 18543354 15138204 12077510
MESH:D013276 Stomach Ulcer Plant Extracts 11.6517135157 18193104 15255614 12787963 18237397
MESH:D013276 Stomach Ulcer Thalidomide 11.6515138204
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.3616321402
MESH:D013705 Temporomandibular Joint Disorders Plant Extracts 12.8417997062
MESH:D013705 Temporomandibular Joint Disorders polyphenols 12.8417997062
MESH:D013921 Thrombocytopenia Lipopolysaccharides 4.0515821434
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.7712697716
MESH:D013964 Thyroid Neoplasms decitabine 7.1717967635
MESH:D013964 Thyroid Neoplasms Indomethacin 7.1714736730 11352223 18791128
MESH:D013978 Tibial Fractures Estradiol 4.5619048282
MESH:D014062 Tongue Neoplasms resveratrol 4.0916227395
MESH:D014456 Ulcer Indomethacin 4.7617380554 10574470
MESH:D001749 Urinary Bladder Neoplasms decitabine 2.6717616700 19087683
MESH:D002583 Uterine Cervical Neoplasms resveratrol 3.9817473185
MESH:D014594 Uterine Neoplasms resveratrol 4.0117044934
MESH:D014604 Uveal Neoplasms decitabine 4.7817785578
MESH:D014605 Uveitis Cyclosporine 3.851336536
MESH:D014652 Vascular Diseases Thalidomide 5.3515741222
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4712125929
MESH:D018487 Ventricular Dysfunction, Left Plant Extracts 10.1018097624
MESH:D018487 Ventricular Dysfunction, Left resveratrol 10.1017488730
MESH:D020257 Ventricular Remodeling Plant Extracts 5.1818097624
MESH:D014839 Vomiting Indomethacin 4.6211897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1215886252
MESH:D014947 Wounds and Injuries Plant Extracts 4.1419894650 20213670
MESH:D014985 Xerophthalmia Cyclosporine 4.3117120751
Pathway ID Pathway Name
KEGG:04514 Cell adhesion molecules (CAMs)
REACT:604 Hemostasis
REACT:6900 Signaling in Immune system
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA35642
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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