AutismKB 2.0

Annotation Detail for SELP


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SELP ( CD62,CD62P,FLJ45155,GMP140,GRMP,LECAM3,PADGEM,PSEL )
Gene Full Name: selectin P (granule membrane protein 140kDa, antigen CD62)
Band: 1q24.2
Quick LinksEntrez ID:6403; OMIM: 173610; Uniprot ID:LYAM3_HUMAN; ENSEMBL ID: ENSG00000174175; HGNC ID: 10721
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05144Malaria
hsa05150Staphylococcus aureus infection
hsa04514Cell adhesion molecules (CAMs)
Pathway IDPathway Name
Hemostasis
Pathway IDPathway Name
200018IL4-mediated signaling events
200108amb2 Integrin signaling
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1758Common cold
1781Rheumatoid arthritis
1818Systemic scleroderma
1842Sickle cell disease
1878Ischemia
1904Diabetes mellitus
1907Depression
1932Pancreatitis
1936Hypercholesterolemia
1997Dental plaque
2023Adrenal gland hyperfunction
2091Hypertension
2053Colon cancer
2066Lung cancer
2146Lupus erythematosus
2199Takayasu's arteritis
2220Dermatitis
2233Cirrhosis
2236Cardiovascular disease
2237Neoplasm metastasis
Desease Name
HEMATOLOGICAL
cognitive function
Atherosclerosis
atherosclerosis, coronary
CARDIOVASCULAR
Coronary Artery Disease
heart disease, ischemic stroke, ischemic
PSYCH
RENAL
P-selectin
atopy-susceptibility
IMMUNE
nephropathy, IgA
Myocardial Infarction
Cardiovascular Diseases
soluble levels of adhesion molecules
thromboembolism, venous
Desease Name
Soluble levels of adhesion molecules
Desease Name
Atopy, susceptibility to
Platelet alpha/delta storage pool deficiency
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of SELP mRNAdecreases expression 19933214
C028451 3,4,3',4'-tetrachlorobiphenyl 3,4,3',4'-tetrachlorobiphenyl results in increased expression of SELP mRNAincreases expression 19608276
C028451 3,4,3',4'-tetrachlorobiphenyl Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of SELP mRNA]decreases reaction|increases expression 19608276
D000079 Acetaldehyde Acetaldehyde results in increased expression of SELP proteinincreases expression 19036374
D000082 Acetaminophen Acetaminophen affects the expression of SELP mRNAaffects expression 17562736
D000117 Acetylglucosamine [Acetylglucosamine analog binds to Biotin] which binds to SELP proteinaffects binding 12191509
D000117 Acetylglucosamine Acetylglucosamine analog binds to SELP proteinaffects binding 12191509
D000171 Acrolein Acrolein results in increased expression of SELP mRNAincreases expression 17982132
D000171 Acrolein Acrolein results in increased expression of SELP proteinincreases expression 17982132
D000244 Adenosine Diphosphate cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]decreases reaction|increases expression 18404433
D000244 Adenosine Diphosphate CYP2C19 gene SNP affects the reaction [Adenosine Diphosphate results in increased expression of SELP protein]affects reaction|increases expression 18394438
D000244 Adenosine Diphosphate N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]decreases reaction|increases expression 18404433
D000244 Adenosine Diphosphate N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate promotes the reaction [cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]]decreases reaction|increases expression|increases reaction 18404433
D000244 Adenosine Diphosphate P2RY12 protein affects the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]affects reaction|increases expression 18404433
D000643 Ammonium Chloride Ammonium Chloride affects the expression of SELP mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in decreased expression of SELP proteindecreases expression 16206674
D001710 Biotin [Acetylglucosamine analog binds to Biotin] which binds to SELP proteinaffects binding 12191509
C074619 bivalirudin bivalirudin inhibits the reaction [F2 protein results in increased expression of SELP protein]decreases reaction|increases expression 16845256
D019819 Budesonide Budesonide inhibits the reaction [lipopolysaccharide, Escherichia coli 0111 B4 results in increased expression of SELP mRNA]decreases reaction|increases expression 15734790
C117446 cangrelor cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]decreases reaction|increases expression 18404433
C117446 cangrelor N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate promotes the reaction [cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]]decreases reaction|increases expression|increases reaction 18404433
C016300 chloramine-T chloramine-T results in decreased expression of SELP proteindecreases expression 11441983
D002713 Chlorine [Ozone co-treated with Chlorine] results in increased expression of SELP mRNAaffects cotreatment|increases expression 18636392
C055162 clopidogrel clopidogrel inhibits the reaction [F2 protein results in increased expression of SELP protein]decreases reaction|increases expression 17043144
C055162 clopidogrel clopidogrel results in decreased expression of SELP mRNAdecreases expression 19155974
C055162 clopidogrel clopidogrel results in decreased expression of SELP proteindecreases expression 19155974
D003474 Curcumin Curcumin inhibits the reaction [F2 protein results in increased expression of SELP protein]decreases reaction|increases expression 18565277
D003474 Curcumin Curcumin inhibits the reaction [TNF protein results in increased expression of SELP protein]decreases reaction|increases expression 18565277
C007488 dinitrobenzenesulfonic acid ALOX5 protein affects the reaction [dinitrobenzenesulfonic acid results in increased expression of SELP protein]affects reaction|increases expression 15821759
C007488 dinitrobenzenesulfonic acid dinitrobenzenesulfonic acid results in increased expression of SELP proteinincreases expression 15821759
C007488 dinitrobenzenesulfonic acid zileuton inhibits the reaction [dinitrobenzenesulfonic acid results in increased expression of SELP protein]decreases reaction|increases expression 15821759
D009240 N-Formylmethionine Leucyl-Phenylalanine ALOX5 protein promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of SELP protein]increases expression|increases reaction 11116075
D009240 N-Formylmethionine Leucyl-Phenylalanine ITGA2B protein promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of SELP protein]increases expression|increases reaction 11116075
D009240 N-Formylmethionine Leucyl-Phenylalanine L 663536 inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of SELP protein]decreases reaction|increases expression 11116075
D009240 N-Formylmethionine Leucyl-Phenylalanine N-Formylmethionine Leucyl-Phenylalanine results in increased expression of SELP proteinincreases expression 11116075
D009240 N-Formylmethionine Leucyl-Phenylalanine PTAFR protein promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of SELP protein]increases expression|increases reaction 11116075
D009240 N-Formylmethionine Leucyl-Phenylalanine SR 121566 inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of SELP protein]decreases reaction|increases expression 11116075
D009240 N-Formylmethionine Leucyl-Phenylalanine SR 27417 inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of SELP protein]decreases reaction|increases expression 11116075
D009240 N-Formylmethionine Leucyl-Phenylalanine zileuton inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of SELP protein]decreases reaction|increases expression 11116075
D019796 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid results in increased expression of SELP proteinincreases expression 11116075
D019796 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid ICI 192605 inhibits the reaction [15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid results in increased expression of SELP protein]decreases reaction|increases expression 11116075
C057498 ICI 192605 ICI 192605 inhibits the reaction [15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid results in increased expression of SELP protein]decreases reaction|increases expression 11116075
D007213 Indomethacin SELP protein affects the susceptibility to Indomethacinaffects response to substance 10486359
C060893 L 663536 L 663536 inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of SELP protein]decreases reaction|increases expression 11116075
C008288 Lipofundin Lipofundin inhibits the reaction [Lipopolysaccharides results in increased expression of SELP protein]decreases reaction|increases expression 16804125
C440499 lipopolysaccharide, Escherichia coli 0111 B4 Budesonide inhibits the reaction [lipopolysaccharide, Escherichia coli 0111 B4 results in increased expression of SELP mRNA]decreases reaction|increases expression 15734790
C440499 lipopolysaccharide, Escherichia coli 0111 B4 lipopolysaccharide, Escherichia coli 0111 B4 results in increased expression of SELP mRNAincreases expression 15734790
C440499 lipopolysaccharide, Escherichia coli 0111 B4 resveratrol affects the reaction [lipopolysaccharide, Escherichia coli 0111 B4 results in increased expression of SELP mRNA]affects reaction|increases expression 15734790
D008070 Lipopolysaccharides Lipofundin inhibits the reaction [Lipopolysaccharides results in increased expression of SELP protein]decreases reaction|increases expression 16804125
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of SELP proteinincreases expression 16804125
D017997 Leukotriene C4 Leukotriene C4 results in increased expression of SELP proteinincreases expression 9152370
D017998 Leukotriene D4 Leukotriene D4 results in increased expression of SELP proteinincreases expression 9152370
C111914 N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]decreases reaction|increases expression 18404433
C111914 N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate promotes the reaction [cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]]decreases reaction|increases expression|increases reaction 18404433
C470148 nilestriol nilestriol results in decreased expression of SELP proteindecreases expression 12934402
D010126 Ozone [Ozone co-treated with Chlorine] results in increased expression of SELP mRNAaffects cotreatment|increases expression 18636392
C002669 parthenolide parthenolide results in decreased expression of SELP mRNAdecreases expression 16921510
C005435 phenylmethylpyrazolone phenylmethylpyrazolone results in decreased expression of SELP proteindecreases expression 16041266
C006253 pirinixic acid pirinixic acid results in decreased expression of SELP mRNAdecreases expression 20059764
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in decreased expression of SELP mRNA]decreases expression|increases reaction 20059764
C006253 pirinixic acid pirinixic acid affects the expression of SELP mRNAaffects expression 16912651
D010972 Platelet Activating Factor Platelet Activating Factor results in increased expression of SELP proteinincreases expression 11116075
D010972 Platelet Activating Factor SR 27417 inhibits the reaction [Platelet Activating Factor results in increased expression of SELP protein]decreases reaction|increases expression 11116075
D011794 Quercetin Quercetin inhibits the reaction [F2 protein results in increased expression of SELP protein]decreases reaction|increases expression 14628445
D011794 Quercetin Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of SELP mRNA]decreases reaction|increases expression 19608276
D020849 Raloxifene Raloxifene affects the expression of SELP proteinaffects expression 15964915
C059514 resveratrol resveratrol inhibits the reaction [F2 protein results in increased expression of SELP protein]decreases reaction|increases expression 16051184
C059514 resveratrol resveratrol affects the reaction [lipopolysaccharide, Escherichia coli 0111 B4 results in increased expression of SELP mRNA]affects reaction|increases expression 15734790
D020123 Sirolimus Sirolimus inhibits the reaction [Zymosan analog results in increased expression of SELP protein]decreases reaction|increases expression 16797888
C106774 SR 121566 SR 121566 inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of SELP protein]decreases reaction|increases expression 11116075
C071317 SR 27417 SR 27417 inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of SELP protein]decreases reaction|increases expression 11116075
C071317 SR 27417 SR 27417 inhibits the reaction [Platelet Activating Factor results in increased expression of SELP protein]decreases reaction|increases expression 11116075
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of SELP mRNAdecreases expression 20055451
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of SELP mRNAdecreases expression 19933214
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in increased expression of SELP proteinincreases expression 16797888
D014212 Tretinoin Tretinoin results in decreased expression of SELP proteindecreases expression 16206674
C063449 zileuton zileuton inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of SELP protein]decreases reaction|increases expression 11116075
C063449 zileuton zileuton inhibits the reaction [dinitrobenzenesulfonic acid results in increased expression of SELP protein]decreases reaction|increases expression 15821759
D015054 Zymosan ALOX5 protein affects the reaction [Zymosan results in increased expression of SELP protein]affects reaction|increases expression 15241586
D015054 Zymosan Zymosan results in increased expression of SELP proteinincreases expression 15241586
D015054 Zymosan Sirolimus inhibits the reaction [Zymosan analog results in increased expression of SELP protein]decreases reaction|increases expression 16797888
D015054 Zymosan Zymosan analog results in increased expression of SELP proteinincreases expression 16797888
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.3711752688 14514962 15322242
MESH:D000138 Acidosis Ammonium Chloride 3.0718287403
MESH:D000152 Acne Vulgaris zileuton 5.2720436887
MESH:D054058 Acute Coronary Syndrome bivalirudin 11.7719804226 10629409
MESH:D054058 Acute Coronary Syndrome clopidogrel 11.7719106084
MESH:D058186 Acute Kidney Injury resveratrol 3.4216538975
MESH:D055371 Acute Lung Injury Acrolein 23.7821297076 20525806
MESH:D055371 Acute Lung Injury Chlorine 23.7820601635
MESH:D055371 Acute Lung Injury Lipopolysaccharides 23.7811850527 18653653
MESH:D055371 Acute Lung Injury pirinixic acid 23.7818653653
MESH:D055371 Acute Lung Injury zileuton 23.7817118201
MESH:D000230 Adenocarcinoma arsenic trioxide 4.1611798837 19825857
MESH:D000230 Adenocarcinoma Indomethacin 4.1616537180
MESH:D000236 Adenoma Indomethacin 6.1111497255
MESH:D000236 Adenoma resveratrol 6.1115688382
MESH:D018248 Adenoma, Liver Cell pirinixic acid 8.2816434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 8.2816835633
MESH:D000419 Albuminuria Raloxifene 4.1317308373 17451421
MESH:D019973 Alcohol-Related Disorders Curcumin 4.5817887948
MESH:D000505 Alopecia Tretinoin 3.2315955085
MESH:D016301 Alveolar Bone Loss Indomethacin 4.8717225004
MESH:D000544 Alzheimer Disease Acrolein 14.1217570602 14715435 15207723
MESH:D000544 Alzheimer Disease Curcumin 14.1215590663
MESH:D000544 Alzheimer Disease Indomethacin 14.1215579461 17627676
MESH:D000544 Alzheimer Disease Ozone 14.1215513908
MESH:D000544 Alzheimer Disease Raloxifene 14.1215800139
MESH:D000544 Alzheimer Disease resveratrol 14.1216162502 16183991
MESH:D000740 Anemia Tetrachlorodibenzodioxin 7.5911748828
MESH:D000740 Anemia Zymosan 7.5918664788
MESH:D000743 Anemia, Hemolytic Quercetin 3.8017084956
MESH:D000799 Angioedema Acetaminophen 3.3510982225
MESH:D001014 Aortic Aneurysm Indomethacin 4.3910231640
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 4.4010388637
MESH:D001161 Arteriosclerosis Acrolein 4.5315014928
MESH:D018771 Arthralgia Indomethacin 4.672160914
MESH:D001169 Arthritis, Experimental resveratrol 10.6617115116
MESH:D001169 Arthritis, Experimental Tretinoin 10.6616412693
MESH:D001169 Arthritis, Experimental Zymosan 10.6615142272 15188379 15944321 17659584 16872482
MESH:D001172 Arthritis, Rheumatoid Curcumin 12.5516807698
MESH:D001172 Arthritis, Rheumatoid Indomethacin 12.5511248219
MESH:D001172 Arthritis, Rheumatoid Ozone 12.5515570426
MESH:D001172 Arthritis, Rheumatoid phenylmethylpyrazolone 12.5516390820
MESH:D001172 Arthritis, Rheumatoid Tretinoin 12.5516292516
MESH:D001249 Asthma Acetaldehyde 16.599600491
MESH:D001249 Asthma Budesonide 16.5910893010 15572850 15136378 18489783 20004779 12604023 12113382
MESH:D001249 Asthma Leukotriene D4 16.598222486 9690572
MESH:D001249 Asthma Ozone 16.5917854713 16373670
MESH:D001249 Asthma Tretinoin 16.5916456186
MESH:D001249 Asthma zileuton 16.5919214143 10764316 17944539 20332717 9620945 10181070 8598621
MESH:D001250 Asthma, Exercise-Induced zileuton 5.1010984370
MESH:D001260 Ataxia Telangiectasia Quercetin 4.4915336622
MESH:D050197 Atherosclerosis Acrolein 9.4417363696 16037261 16126721
MESH:D050197 Atherosclerosis Curcumin 9.4418704882
MESH:D050197 Atherosclerosis resveratrol 9.4417967414 16873680
MESH:D001321 Autistic Disorder Acetaminophen 2.3018445737
MESH:D001321 Autistic Disorder Sirolimus 2.3021115397
MESH:D001327 Autoimmune Diseases Curcumin 9.2919761891
MESH:D001327 Autoimmune Diseases Quercetin 9.2919761891
MESH:D001471 Barrett Esophagus Tretinoin 3.9416935849
MESH:D001477 Bartter Syndrome Indomethacin 4.5110684365
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 18.3716206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 18.3719483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 18.3712125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 18.3716206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.2915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.4415746008
MESH:D001929 Brain Edema Indomethacin 11.2211481608
MESH:D001929 Brain Edema zileuton 11.2219309543
MESH:D001930 Brain Injuries Raloxifene 4.0016580743
MESH:D002545 Brain Ischemia Curcumin 14.2916770732
MESH:D002545 Brain Ischemia Indomethacin 14.2912524144
MESH:D002545 Brain Ischemia resveratrol 14.2917600658
MESH:D001932 Brain Neoplasms Curcumin 3.5217596214
MESH:D001943 Breast Neoplasms Curcumin 4.2316243823 19250217 18593918 18462866
MESH:D001943 Breast Neoplasms Indomethacin 4.2317401462
MESH:D001943 Breast Neoplasms parthenolide 4.2316873071
MESH:D001943 Breast Neoplasms Quercetin 4.2318628248
MESH:D001943 Breast Neoplasms Raloxifene 4.2317049068 16912660 17440819 17893378 16837676 17242785 15758505 15572757 17595753 15775269 17952589 17261762
MESH:D001943 Breast Neoplasms resveratrol 4.2317651959 17534123 16393696
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 4.2320435547
MESH:D001943 Breast Neoplasms Tretinoin 4.2316166294 16443354 16873071
MESH:D016535 Bronchial Hyperreactivity Leukotriene C4 17.1912654629
MESH:D016535 Bronchial Hyperreactivity Leukotriene D4 17.1912654629 12794006
MESH:D016535 Bronchial Hyperreactivity Ozone 17.1919059883 18315731 17626835 15516495 14754758 18417511 16777450
MESH:D016535 Bronchial Hyperreactivity zileuton 17.1912794006 12388339 12654629
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.1016813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.8811589617
MESH:D002056 Burns Indomethacin 4.2310459503
MESH:D002100 Cachexia Indomethacin 10.7815625704 16537180 15141370 11239499
MESH:D002100 Cachexia Ozone 10.7816183385
MESH:D002105 Cadmium Poisoning Quercetin 5.0516962696
MESH:D002277 Carcinoma Curcumin 7.0018593918
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.0016835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.6616168501
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 12.553084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 12.5511135700 14691202 15073043 16217749 15553829
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 12.5516391822
MESH:D006528 Carcinoma, Hepatocellular Quercetin 12.5512508355 19519916
MESH:D006528 Carcinoma, Hepatocellular resveratrol 12.5519321006 16227395
MESH:D006528 Carcinoma, Hepatocellular Sirolimus 12.5519335982
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 12.551917145
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 9.8011053908
MESH:D018827 Carcinoma, Lewis Lung resveratrol 9.8016675471
MESH:D018276 Carcinoma, Medullary Indomethacin 4.8618791128 14736730 11352223
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 2.7918414057
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.4817234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.3819014326
MESH:D002292 Carcinoma, Renal Cell Indomethacin 3.1317341418
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.6912490120
MESH:D002294 Carcinoma, Squamous Cell Curcumin 15.9118462866
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 15.9115482327 12636206
MESH:D002294 Carcinoma, Squamous Cell resveratrol 15.9116227395
MESH:D002294 Carcinoma, Squamous Cell Sirolimus 15.9119435901
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 15.9118922899
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 15.9116096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 3.6517572228
MESH:D006332 Cardiomegaly Quercetin 5.8519794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 5.8518670907 18850075 16120746
MESH:D002310 Cardiomyopathy, Alcoholic Acetaldehyde 5.9810525098
MESH:D002318 Cardiovascular Diseases clopidogrel 10.4320180610
MESH:D002318 Cardiovascular Diseases Raloxifene 10.4315775269
MESH:D002318 Cardiovascular Diseases resveratrol 10.4315458977
MESH:D020212 Carotid Artery Injuries bivalirudin 6.1111316950
MESH:D002386 Cataract Acetaminophen 6.2310977129
MESH:D002386 Cataract Tretinoin 6.2317460283
MESH:D002543 Cerebral Hemorrhage phenylmethylpyrazolone 5.3519095969
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.1016129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.7516835633
MESH:D002764 Cholecystitis Indomethacin 4.6711181007
MESH:D002779 Cholestasis pirinixic acid 2.4619176532
MESH:D002822 Choriocarcinoma Tretinoin 4.6616461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.0212621046 16354765 15340226 8697196 15668235
MESH:D002972 Cleft Palate Tretinoin 5.029407595
MESH:D003072 Cognition Disorders Raloxifene 4.1415800139
MESH:D003092 Colitis Curcumin 19.0716804969 18200517 16782535
MESH:D003092 Colitis dinitrobenzenesulfonic acid 19.0716680017 16670640 15821759
MESH:D003092 Colitis resveratrol 19.0716474422
MESH:D003092 Colitis Tretinoin 19.0717035595
MESH:D003103 Coloboma Curcumin 4.1118809619
MESH:D003110 Colonic Neoplasms Curcumin 9.8919359593 16340194
MESH:D003110 Colonic Neoplasms Indomethacin 9.8915786552 11260862 15963497 15936596 15625704 15637740
MESH:D003110 Colonic Neoplasms Quercetin 9.8916640504 15741050 11134977 17191121 19440933 17148506 19056647
MESH:D003110 Colonic Neoplasms resveratrol 9.8916338953
MESH:D003110 Colonic Neoplasms zileuton 9.8918927292
MESH:D015179 Colorectal Neoplasms Acrolein 5.8517597105
MESH:D015179 Colorectal Neoplasms arsenic trioxide 5.8520501625
MESH:D015179 Colorectal Neoplasms Indomethacin 5.8518059344 12606626 11197048 17054584
MESH:D015179 Colorectal Neoplasms Quercetin 5.8518852136 18095365
MESH:D015179 Colorectal Neoplasms resveratrol 5.8516550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.6517141729 14669216
MESH:D016510 Corneal Neovascularization Curcumin 4.4218497527
MESH:D003327 Coronary Disease resveratrol 3.4316507316
MESH:D023903 Coronary Restenosis arsenic trioxide 3.7212609071
MESH:D003328 Coronary Thrombosis bivalirudin 5.3218036681
MESH:D018352 Coronavirus Infections Indomethacin 5.2217302372
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.3910525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.3910048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 3.399125849 16925845 8800419 17551590 14991402 10589399 9664655 9224671 9142499 9211117
MESH:D003556 Cystitis Acrolein 4.9012161096
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.6515213294
MESH:D003665 Decompression Sickness zileuton 5.7318309904
MESH:D003865 Depressive Disorder, Major Raloxifene 3.7517474826
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.1818249437
MESH:D048909 Diabetes Complications bivalirudin 5.8618436116
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 7.2419496084
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 7.2416873680
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 3.9318403477
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 3.9317107852
MESH:D003928 Diabetic Nephropathies Curcumin 12.8018204486
MESH:D003928 Diabetic Nephropathies Raloxifene 12.8015920148 17308373 17451421
MESH:D003928 Diabetic Nephropathies resveratrol 12.8016286809
MESH:D003967 Diarrhea Indomethacin 3.347907874 7237001
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 5.3511461765 19420014 10915739 11529661 16109766 10663392 16781746 17522070 19416960 16227642 18713872 15619225 12153990 12392966 11287661 16393943 17906064 19370779 12705907 12594235 19739265 19164858 16177239 17562736 15968718 11743745 14725611 19923254 19085960 12958197 18071297 16485898 11739529 16081117 14986274 14550746 11834606 11421492 10774834 12540782 2444490
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 5.3520420201
MESH:D056486 Drug-Induced Liver Injury zileuton 5.3517944539
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.6019426721
MESH:D004362 Drug Toxicity phenylmethylpyrazolone 7.3312649298 12231392
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 7.3311462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 4.6612774134 16326151 16133044 17190690 18446180 18043480
MESH:D004381 Duodenal Ulcer Curcumin 7.8917351913
MESH:D004381 Duodenal Ulcer Indomethacin 7.8917329845 17202747 10671773 11595415 17045617 17351913 11535926 11595431 17151854 11991626 16699067
MESH:D004417 Dyspnea Budesonide 9.3020016425
MESH:D004417 Dyspnea Chlorine 9.3020016425
MESH:D004487 Edema Indomethacin 35.5716100529 7907874 10653021 8273558 19703484 7990266 8985016
MESH:D004487 Edema L 663536 35.577990266
MESH:D004487 Edema pirinixic acid 35.5712083418
MESH:D004487 Edema Raloxifene 35.5715860553
MESH:D004487 Edema resveratrol 35.578985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 35.5712711302 11000095
MESH:D004487 Edema Tetradecanoylphorbol Acetate 35.5715177302 11698051 9599246 8113982 16716910 8273558 7812673
MESH:D004487 Edema zileuton 35.577990266 7812673 8273558 11698051 17118201 9831321 19703484
MESH:D004487 Edema Zymosan 35.577907874
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.2916714409 18230668 15322242
MESH:D004489 Edema, Cardiac Tretinoin 10.2918230668
MESH:D016769 Embolism and Thrombosis bivalirudin 5.4616084352
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 7.8915845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 7.8917872969
MESH:D016889 Endometrial Neoplasms Tretinoin 2.7816569247
MESH:D004715 Endometriosis Indomethacin 7.6715652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 7.6710568697 9294722
MESH:D019446 Endotoxemia Indomethacin 27.6118509659
MESH:D019446 Endotoxemia lipopolysaccharide, Escherichia coli 0111 B4 27.6112954792
MESH:D019446 Endotoxemia Lipopolysaccharides 27.6115328337 17637181 15821434
MESH:D019446 Endotoxemia phenylmethylpyrazolone 27.6112954792
MESH:D019446 Endotoxemia zileuton 27.6115328337
MESH:D004751 Enteritis Indomethacin 4.2517763956 10567023 16328016
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 10.7917980183
MESH:D020345 Enterocolitis, Necrotizing resveratrol 10.7917923197
MESH:D004802 Eosinophilia Indomethacin 7.9211298111
MESH:D004802 Eosinophilia zileuton 7.9210764316 8621850
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.2412903497
MESH:D004938 Esophageal Neoplasms Indomethacin 4.2411005569
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.6111564622
MESH:D005124 Eye Abnormalities Tretinoin 7.6116938888 9664655
MESH:D005234 Fatty Liver arsenic trioxide 20.0915073043
MESH:D005234 Fatty Liver Curcumin 20.0919297423
MESH:D005234 Fatty Liver phenylmethylpyrazolone 20.0912795759
MESH:D005234 Fatty Liver pirinixic acid 20.0919236843 20131406
MESH:D005234 Fatty Liver Raloxifene 20.0917473493
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.9811858732
MESH:D005334 Fever Indomethacin 13.0317627676 11852909 10431976
MESH:D005334 Fever lipopolysaccharide, Escherichia coli 0111 B4 13.0316997862
MESH:D005334 Fever Lipopolysaccharides 13.039205823 11852909
MESH:D005354 Fibrosarcoma Indomethacin 4.4110962813
MESH:D005355 Fibrosis Curcumin 22.7318705752
MESH:D005355 Fibrosis Indomethacin 22.7317994277
MESH:D005355 Fibrosis Quercetin 22.7319474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 22.7320067830
MESH:D005355 Fibrosis Tretinoin 22.7317994277
MESH:D005499 Folliculitis Indomethacin 4.6711298111
MESH:D005596 Fractures, Closed zileuton 5.3619544365
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.8016904648
MESH:D005739 Gas Poisoning Budesonide 10.6420016425
MESH:D005739 Gas Poisoning Chlorine 10.6420016425
MESH:D005756 Gastritis Acetaminophen 9.5016983495
MESH:D005756 Gastritis Indomethacin 9.5015046732
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.2218462866
MESH:D005909 Glioblastoma Curcumin 14.3017596214
MESH:D005909 Glioblastoma Indomethacin 14.3012870263
MESH:D005909 Glioblastoma Quercetin 14.3019804834
MESH:D005909 Glioblastoma Tretinoin 14.3017312396
MESH:D005910 Glioma Indomethacin 5.6016487511 18371953
MESH:D005910 Glioma Quercetin 5.6017643826
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 3.9011849393
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.1010696789
MESH:D006073 Gout Indomethacin 4.8611248219
MESH:D006258 Head and Neck Neoplasms Curcumin 15.7718829502 18462866
MESH:D006258 Head and Neck Neoplasms Indomethacin 15.7715482327
MESH:D006258 Head and Neck Neoplasms Sirolimus 15.7719435901
MESH:D006258 Head and Neck Neoplasms Tretinoin 15.7716096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.6616084493
MESH:D006330 Heart Defects, Congenital 3,4,3',4'-tetrachlorobiphenyl 9.7711294989
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 9.7710048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 9.779664655 14991402
MESH:D006331 Heart Diseases Raloxifene 3.1911110106
MESH:D006333 Heart Failure pirinixic acid 2.2320558911
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 3.9616366002
MESH:D006470 Hemorrhage bivalirudin 9.2218436116 16125490 16598112 19360860 19147609 19281522
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 9.2211000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 4.1315633222
MESH:D006505 Hepatitis Zymosan 4.2419110552
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.2215135802
MESH:D006529 Hepatomegaly pirinixic acid 11.8319176532 19772884 16221962 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 11.8312621046 16120746 15340226
MESH:D006529 Hepatomegaly zileuton 11.838661344
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.5617701891
MESH:D006561 Herpes Simplex resveratrol 3.7016876885
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.5516354765 8697196 18606429 15340226 16959395
MESH:D006930 Hyperalgesia Acetaminophen 10.8416870215
MESH:D006930 Hyperalgesia Indomethacin 10.8412727271
MESH:D006930 Hyperalgesia Tretinoin 10.8416870215
MESH:D034321 Hyperamylasemia Indomethacin 5.2217883296
MESH:D006937 Hypercholesterolemia Curcumin 7.9418704882
MESH:D006937 Hypercholesterolemia resveratrol 7.9417188708
MESH:D006940 Hyperemia Indomethacin 4.5212524144
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.0916778211
MESH:D006943 Hyperglycemia pirinixic acid 7.8420558911
MESH:D006943 Hyperglycemia Quercetin 7.8418262572 11834736
MESH:D006949 Hyperlipidemias Indomethacin 8.0017546600
MESH:D006949 Hyperlipidemias resveratrol 8.0016873680
MESH:D006967 Hypersensitivity marker/mechanism
MESH:D006973 Hypertension Quercetin 7.4718356687
MESH:D006973 Hypertension Raloxifene 7.4717577099 15787275
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 7.4718850075 18670907
MESH:D006976 Hypertension, Pulmonary L 663536 7.9914726295
MESH:D006976 Hypertension, Pulmonary zileuton 7.9914726295
MESH:D006984 Hypertrophy Sirolimus 4.7919211884
MESH:D017379 Hypertrophy, Left Ventricular phenylmethylpyrazolone 9.3715824197
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 9.3717488730
OMIM:147050 IgE RESPONSIVENESS, ATOPIC marker/mechanism
MESH:D007077 Ileal Diseases Indomethacin 4.5318306037 10574470
MESH:D007079 Ileitis Indomethacin 4.8610651667 16133968 10647630
MESH:D007235 Infant, Premature, Diseases Indomethacin 4.8716133044
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 10.3617600658
MESH:D020244 Infarction, Middle Cerebral Artery zileuton 10.3619309543
MESH:D007249 Inflammation bivalirudin 27.8216125490
MESH:D007249 Inflammation Curcumin 27.8218403477 16956363 17151092
MESH:D007249 Inflammation Indomethacin 27.827812673 3291741 12568917
MESH:D007249 Inflammation Lipopolysaccharides 27.8217237260 17255318 12878042 9205823 17963957
MESH:D007249 Inflammation resveratrol 27.8216366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 27.8212200463 12878042
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 27.828273558 15177302 7812673 7562506 11698051
MESH:D007249 Inflammation zileuton 27.828960868 9831321 18309904 8621850 7812673 17118201 18295198 18059327
MESH:D007249 Inflammation Zymosan 27.8211289658 8014878
MESH:D015212 Inflammatory Bowel Diseases Curcumin 6.1818200517 18596194
MESH:D015212 Inflammatory Bowel Diseases zileuton 6.1815339030
MESH:D007251 Influenza, Human Quercetin 9.5416624496
MESH:D007251 Influenza, Human resveratrol 9.5416624496
MESH:D007333 Insulin Resistance pirinixic acid 2.3116306350
MESH:D007410 Intestinal Diseases Indomethacin 8.3117329856 11855677 11713966 17994277 15831440 10210152 15610444 18236018 11686837
MESH:D007410 Intestinal Diseases Tretinoin 8.3117994277
MESH:D007414 Intestinal Neoplasms Curcumin 3.8010783313
MESH:D002532 Intracranial Aneurysm phenylmethylpyrazolone 4.8519381132
MESH:D019586 Intracranial Hypertension Indomethacin 4.8715241188
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.1817255318
MESH:D043183 Irritable Bowel Syndrome Zymosan 5.3517553498
MESH:D007511 Ischemia bivalirudin 10.2718436116
MESH:D007511 Ischemia phenylmethylpyrazolone 10.2716301206
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.4816580747
MESH:D007569 Jaw Abnormalities Tretinoin 8.4817551590 15992940
MESH:D007579 Jejunal Diseases Indomethacin 4.5318306037 10574470 16133968
MESH:D007627 Keloid Quercetin 4.4817086741
MESH:D007674 Kidney Diseases Acetaminophen 15.9812587719 15629191
MESH:D007674 Kidney Diseases Acrolein 15.9812488133
MESH:D007674 Kidney Diseases Indomethacin 15.9817190690
MESH:D007674 Kidney Diseases phenylmethylpyrazolone 15.9818085390
MESH:D007674 Kidney Diseases Quercetin 15.9816962696
MESH:D007889 Leiomyoma Curcumin 9.6618555241
MESH:D007889 Leiomyoma Raloxifene 9.6616973256
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.5110320625 12228301 11703811
MESH:D007938 Leukemia arsenic trioxide 12.8415070760
MESH:D007938 Leukemia Curcumin 12.8418462866
MESH:D007938 Leukemia Quercetin 12.8417468513
MESH:D007938 Leukemia Tretinoin 12.8417143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 8.3217077332 12560223
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 8.3216106398
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.8216972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 12.1314633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 12.1310785260 16572323 15631656
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive zileuton 12.1319503090 19823023
MESH:D007951 Leukemia, Myeloid arsenic trioxide 8.0319077051
MESH:D007951 Leukemia, Myeloid Tretinoin 8.0316932348 19285840 16482212
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 5.5316968895 17050201 20471514 19850784 16467208
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 5.5318360721
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 5.5317596541 16294345 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 10.8815213294 17217047 15622746 17107899 12712474 16330433 17649720 15336539 16891316 17712046 19075265 12018890 16823087 11468182 9834237 19035177 15748426 12679006 16331271 19225113 16112521 19642359 16966277 17869043 11161223
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 10.8816087638
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 10.8819035177 17339181 16935935 17368321 16891316 19225113 17649720 19029980 17301526 9834237 19642359 17107899 16823087 15748426 16788101 16331271 17361223 16766008 17294898 17217047 19075265 17506722 17712046 16140955 12679006
MESH:D015458 Leukemia, T-Cell arsenic trioxide 10.1716882451
MESH:D015458 Leukemia, T-Cell Curcumin 10.1716106398
MESH:D007964 Leukocytosis Indomethacin 4.8716537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.2217980183
MESH:D007970 Leukopenia Lipopolysaccharides 4.2115821434
MESH:D017880 Limb Deformities, Congenital Tretinoin 2.959224671
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.2211479899
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 11.8618705752 17355460 18006644
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 11.8618194892
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 11.8612878042
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 11.8615474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 11.8612741479
MESH:D008106 Liver Cirrhosis, Experimental Sirolimus 11.8617050028
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 11.8612878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 11.8618397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 3.6111587558 12969438 19014921 16611625 19460945 19784758 16610002 12587719
MESH:D008107 Liver Diseases Curcumin 3.6116956363
MESH:D017114 Liver Failure, Acute Acetaminophen 2.8116871587 17185352
MESH:D008113 Liver Neoplasms arsenic trioxide 12.0214682389
MESH:D008113 Liver Neoplasms pirinixic acid 12.0215890375 16377806 20007298
MESH:D008113 Liver Neoplasms Quercetin 12.0218980244
MESH:D008113 Liver Neoplasms resveratrol 12.0219073162 19812893 19321006 20405173
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 12.0216984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 8.0420377131
MESH:D008114 Liver Neoplasms, Experimental Quercetin 8.0419519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 8.0412151625
MESH:D008133 Long QT Syndrome arsenic trioxide 2.9815213294
MESH:D008171 Lung Diseases Acrolein 6.7811504702
MESH:D008171 Lung Diseases Ozone 6.788266340 19066396
MESH:D055370 Lung Injury Lipopolysaccharides 7.6721114838
MESH:D055370 Lung Injury Ozone 7.6720417186
MESH:D008175 Lung Neoplasms Acetaldehyde 16.2117372256
MESH:D008175 Lung Neoplasms arsenic trioxide 16.2111798837 19825857
MESH:D008175 Lung Neoplasms Budesonide 16.2116885199 12117777 17163412
MESH:D008175 Lung Neoplasms Curcumin 16.2116243823 19359593 18462866
MESH:D008175 Lung Neoplasms Indomethacin 16.2111497255 11053908 16537180
MESH:D008175 Lung Neoplasms L 663536 16.2115899809
MESH:D008175 Lung Neoplasms Ozone 16.217614698 8597069
MESH:D008175 Lung Neoplasms Quercetin 16.2116280456
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 16.2119555203 11884234
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 16.2111807781
MESH:D008223 Lymphoma Curcumin 3.2418462866
MESH:D016393 Lymphoma, B-Cell resveratrol 3.8517088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.4714749477
MESH:D016399 Lymphoma, T-Cell Curcumin 4.2216173963
MESH:D015674 Mammary Neoplasms, Animal resveratrol 3.7615688416
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 5.3811606380 8985016
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 5.388985016
MESH:D008527 Medulloblastoma Tretinoin 2.5717453147
MESH:D008545 Melanoma Curcumin 6.4918462866 17885582
MESH:D008545 Melanoma resveratrol 6.4917992120
MESH:D008545 Melanoma Sirolimus 6.4919282848
MESH:D008545 Melanoma Tretinoin 6.4916752155
MESH:D008546 Melanoma, Experimental Acetaminophen 9.4019513568
MESH:D008546 Melanoma, Experimental Acrolein 9.4010803710
MESH:D008569 Memory Disorders Curcumin 3.6917263510
MESH:D008591 Meningomyelocele Tretinoin 3.9516940565
MESH:D008659 Metabolic Diseases phenylmethylpyrazolone 9.5916301206
MESH:D008659 Metabolic Diseases resveratrol 9.5917112576
MESH:D008679 Metaplasia Ozone 4.6110496685
MESH:D008881 Migraine Disorders Indomethacin 3.3211903285
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.0615863610
MESH:D009062 Mouth Neoplasms Indomethacin 7.9712636206
MESH:D009062 Mouth Neoplasms Sirolimus 7.9719435901
MESH:D009101 Multiple Myeloma arsenic trioxide 14.4019417148 14977855 15949261 11468182 19549372
MESH:D009101 Multiple Myeloma Curcumin 14.4019372569
MESH:D009101 Multiple Myeloma Raloxifene 14.4016497877
MESH:D009101 Multiple Myeloma resveratrol 14.4014749477 16267019 16490592 17164350 17049120 17935668
MESH:D009102 Multiple Organ Failure Zymosan 4.7615834315 12130978 12879239 18160304 10890648 15259001 15213630 15241586 17724436 10479408
MESH:D009134 Muscular Atrophy, Spinal Curcumin 10.7917962980
MESH:D009134 Muscular Atrophy, Spinal resveratrol 10.7917962980
MESH:D009135 Muscular Diseases pirinixic acid 3.0316239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.1718349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 6.4116882451 16105982
MESH:D009190 Myelodysplastic Syndromes Tretinoin 6.4117596541
MESH:D009203 Myocardial Infarction marker/mechanism
MESH:D009203 Myocardial Infarction pirinixic acid 8.2119151258
MESH:D009203 Myocardial Infarction Quercetin 8.2119595682
MESH:D009203 Myocardial Infarction resveratrol 8.2116317513 16456233 16525036 17015251 17188708 17125593
MESH:D017202 Myocardial Ischemia bivalirudin 13.2810562259
MESH:D017202 Myocardial Ischemia resveratrol 13.2817015251 17125593
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 13.2812213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.1916411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 7.1919207477
MESH:D009205 Myocarditis resveratrol 4.2717322642
MESH:D009232 Myxoma Raloxifene 5.0616343187
MESH:D009298 Nasal Polyps zileuton 5.7310665187
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 8.7916624393
MESH:D009361 Neoplasm Invasiveness Curcumin 8.7918495463
MESH:D009362 Neoplasm Metastasis clopidogrel 5.8211875746
MESH:D009362 Neoplasm Metastasis Indomethacin 5.8211053908 16537180 11239499
MESH:D009369 Neoplasms Acrolein 9.7817329238
MESH:D009369 Neoplasms pirinixic acid 9.7817405874
MESH:D009369 Neoplasms Quercetin 9.7815185748
MESH:D009369 Neoplasms Tretinoin 9.7816946489 16594593
MESH:D009374 Neoplasms, Experimental Indomethacin 7.8310663608 15625704
MESH:D009374 Neoplasms, Experimental resveratrol 7.838985016
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 4.0412497104
MESH:D009389 Neovascularization, Pathologic parthenolide 5.0416921510
MESH:D009393 Nephritis Acrolein 5.7912653641
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 7.9814600291
MESH:D009421 Nervous System Malformations Tretinoin 7.989125849
MESH:D009423 Nervous System Neoplasms Curcumin 5.1318462866
MESH:D009436 Neural Tube Defects arsenic trioxide 6.2110525206
MESH:D009436 Neural Tube Defects Tretinoin 6.219142499
MESH:D019636 Neurodegenerative Diseases Acetaminophen 16.9018514411
MESH:D019636 Neurodegenerative Diseases Acrolein 16.9011342003
MESH:D019636 Neurodegenerative Diseases Indomethacin 16.9012349958
MESH:D019636 Neurodegenerative Diseases resveratrol 16.9017652729
MESH:D020078 Neurogenic Inflammation Quercetin 9.2017929310
MESH:D020078 Neurogenic Inflammation resveratrol 9.2017929310
MESH:D009765 Obesity Curcumin 4.1219297423
MESH:D009765 Obesity pirinixic acid 4.1220558911
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.676374098
MESH:D010003 Osteoarthritis Indomethacin 3.367009135
MESH:D010024 Osteoporosis Curcumin 6.3718719352
MESH:D010024 Osteoporosis Raloxifene 6.3717882678 19059307 15775268
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 14.3219495926
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 14.3215579764 17823083 17893378 15758505
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 14.3217513867
MESH:D010051 Ovarian Neoplasms arsenic trioxide 9.8616624393 19769630 12452020
MESH:D010051 Ovarian Neoplasms Curcumin 9.8619020741 18462866
MESH:D010051 Ovarian Neoplasms Quercetin 9.8619005980
MESH:D010051 Ovarian Neoplasms Tretinoin 9.8616936753
MESH:D010146 Pain Acetaminophen 12.9416870215
MESH:D010146 Pain Indomethacin 12.943291741 17440234 13679232 17627676
MESH:D010146 Pain Tretinoin 12.9416870215
MESH:D010146 Pain zileuton 12.9415935457
MESH:D010149 Pain, Postoperative Indomethacin 4.1818702446 12538197
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 17.9415580305
MESH:D010190 Pancreatic Neoplasms Curcumin 17.9417440100 19196508 19401701
MESH:D010190 Pancreatic Neoplasms L 663536 17.9412384795
MESH:D010190 Pancreatic Neoplasms Quercetin 17.9416965848
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 17.9415976015
MESH:D010190 Pancreatic Neoplasms Tretinoin 17.9415976015
MESH:D010195 Pancreatitis Indomethacin 7.6015028970 17883296
MESH:D010195 Pancreatitis phenylmethylpyrazolone 7.6020035747
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 3.828330346 12065085 18922899 18404319
MESH:D010235 Paraganglioma arsenic trioxide 3.7119927285
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.2216537180
MESH:D010300 Parkinson Disease Acrolein 5.4717690948
MESH:D010300 Parkinson Disease Sirolimus 5.4719682553
MESH:D020734 Parkinsonian Disorders Indomethacin 3.7012349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.2211903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.7512520081
MESH:D010437 Peptic Ulcer Indomethacin 4.6611148446
MESH:D010518 Periodontitis Indomethacin 4.4217225004
MESH:D010538 Peritonitis Ozone 14.4116369182
MESH:D010538 Peritonitis zileuton 14.4117371808
MESH:D010538 Peritonitis Zymosan 14.4118977430 15259001 14761945 19088179 18760300 18557954 19641140 17371808 11985352 15979727 17826846
MESH:D010787 Photosensitivity Disorders Acrolein 5.2411550810
MESH:D011014 Pneumonia Lipopolysaccharides 9.4812224865 11605937
MESH:D011014 Pneumonia Ozone 9.4818007984 18929643 18381685
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.1018163543
MESH:D011230 Precancerous Conditions Quercetin 3.5719056647
MESH:D047928 Premature Birth Indomethacin 4.6517000239
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 7.9816679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 7.9811896295 11118676 11399792 11222880
MESH:D011471 Prostatic Neoplasms arsenic trioxide 1.8919131511
MESH:D011471 Prostatic Neoplasms Curcumin 1.8918769126 15129424 18156803 10851300 12497104 18226269 11398177
MESH:D011471 Prostatic Neoplasms parthenolide 1.8916921510
MESH:D011471 Prostatic Neoplasms Quercetin 1.8914715546 17292933
MESH:D011471 Prostatic Neoplasms Raloxifene 1.8916536755 16220300 15731164
MESH:D011471 Prostatic Neoplasms resveratrol 1.8917718901 17675339 16731767 17636462 15767336 17804756
MESH:D011507 Proteinuria Indomethacin 7.8511849393
MESH:D011507 Proteinuria Tretinoin 7.8516636307
MESH:D011537 Pruritus L 663536 9.1517827870
MESH:D011537 Pruritus zileuton 9.1519657356 17827870
MESH:D011625 Pterygium Tretinoin 4.3016723453
MESH:D011654 Pulmonary Edema zileuton 4.9318309904
MESH:D011656 Pulmonary Emphysema Curcumin 4.1019168576
MESH:D011693 Purpura Raloxifene 5.0615770314
MESH:D051437 Renal Insufficiency Acrolein 4.5312732208
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.0916325855
MESH:D015427 Reperfusion Injury Leukotriene C4 17.8912967936
MESH:D015427 Reperfusion Injury phenylmethylpyrazolone 17.8916041266 14654979 15086910 15948865 16753835 15629865
MESH:D015427 Reperfusion Injury pirinixic acid 17.8919058328
MESH:D015427 Reperfusion Injury resveratrol 17.8917520802 16317513 15827377 17058453 16314181
MESH:D015427 Reperfusion Injury zileuton 17.899865762 15266012
MESH:D012120 Respiration Disorders Chlorine 4.7218579056
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 3.5818379247 10666014
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.4010835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.3718990726
MESH:D012170 Retinal Vein Occlusion clopidogrel 5.6519371211
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.6516283617 16116481
MESH:D012220 Rhinitis Acetaldehyde 8.1317050345
MESH:D012220 Rhinitis zileuton 8.1320332717
MESH:D012509 Sarcoma Curcumin 3.6918462866
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.5016646077
MESH:D012554 Schistosomiasis japonica Quercetin 5.0516862918
MESH:D018805 Sepsis Curcumin 8.3618389075
MESH:D018805 Sepsis Zymosan 8.3611441115
MESH:D012852 Sinusitis zileuton 5.0310665187
MESH:D012878 Skin Neoplasms resveratrol 11.558985016 15837718
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 11.5516192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 11.5518404319 12065085 8330346 8985016 11807781
MESH:D012878 Skin Neoplasms Tretinoin 11.5516467112
MESH:D020181 Sleep Apnea, Obstructive zileuton 5.3719118273
MESH:D013119 Spinal Cord Injuries zileuton 5.0318059327
MESH:D013272 Stomach Diseases Indomethacin 3.9318209964 18545984 10486359 10192188 15038085 15472012 17160473 16280098 10215738 16113693 17638125 17207306 16184426
MESH:D013274 Stomach Neoplasms arsenic trioxide 3.1317007042
MESH:D013274 Stomach Neoplasms Indomethacin 3.1315609394
MESH:D013274 Stomach Neoplasms Tretinoin 3.1317261132
MESH:D013276 Stomach Ulcer Curcumin 9.9116631530 19188055
MESH:D013276 Stomach Ulcer Indomethacin 9.9118209962 15138204 17918041 12077510 17654042 10423059 17657623 17135157 12787963 11906479 16169175 15104355 16252198 11523592 15255614 18431645 1323529 18299717 11145282 10750652 18237397 18543354 18726076 14567935 12500499 17895592 11595431 16631530 16934674 17977527 18193104 11595415 18181030 16150113 12498302 18087811 16755016 12467913 17627676 10878458 16397915 11729361
MESH:D013276 Stomach Ulcer Leukotriene D4 9.911323529
MESH:D020521 Stroke Acrolein 12.5616269634
MESH:D020521 Stroke bivalirudin 12.5614683561
MESH:D020521 Stroke Raloxifene 12.5616837676
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.0516321402
MESH:D013921 Thrombocytopenia bivalirudin 8.9916893407 16651880
MESH:D013921 Thrombocytopenia Lipopolysaccharides 8.9915821434
MESH:D013927 Thrombosis bivalirudin 5.1616893407 8456428 9125671 15979436 14593979
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.4112697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 9.9019014326
MESH:D013964 Thyroid Neoplasms Indomethacin 9.9018791128 14736730 11352223
MESH:D013964 Thyroid Neoplasms Tretinoin 9.9016026305 17045167
MESH:D013978 Tibial Fractures Raloxifene 4.7119048282
MESH:D014062 Tongue Neoplasms resveratrol 8.5016227395
MESH:D014062 Tongue Neoplasms Tretinoin 8.5016051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.4815213294
MESH:D014376 Tuberculosis Tretinoin 2.9116040207
MESH:D014402 Tuberous Sclerosis Sirolimus 5.1018495876 21115397
MESH:D014456 Ulcer Indomethacin 4.4110574470 17380554
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 10.2320435036 11780464 12845720 12973940
MESH:D001749 Urinary Bladder Neoplasms Curcumin 10.2318593936
MESH:D001749 Urinary Bladder Neoplasms Quercetin 10.2316720314
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 10.2317572228
MESH:D014565 Urogenital Neoplasms Curcumin 4.7818462866
MESH:D014581 Urticaria Acetaminophen 2.5310982225
MESH:D002583 Uterine Cervical Neoplasms resveratrol 8.1317473185
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 8.1316129372
MESH:D014594 Uterine Neoplasms resveratrol 3.6817044934
MESH:D014604 Uveal Neoplasms Tretinoin 4.1116752155
MESH:D014605 Uveitis Sirolimus 10.941336536
MESH:D014605 Uveitis Zymosan 10.9411006244
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.1012125929
MESH:D054556 Venous Thromboembolism Raloxifene 4.7116837676
MESH:D018487 Ventricular Dysfunction, Left resveratrol 3.8317488730
MESH:D014820 Vitiligo Tretinoin 3.5916761959
MESH:D014839 Vomiting Indomethacin 4.2511897121
MESH:D014846 Vulvar Neoplasms Raloxifene 5.0616343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.7515886252
MESH:D009396 Wilms Tumor Tretinoin 3.5616287080
Pathway ID Pathway Name
KEGG:04514 Cell adhesion molecules (CAMs)
REACT:604 Hemostasis
KEGG:05144 Malaria
KEGG:05150 Staphylococcus aureus infection
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA35643
    • No data
    Releated disease ID Related disease Name
    PA444552Hypertension
    No data
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB01109 inhibitor Heparin Anticoagulants;Heparins
    DB02612 - 1na
    DB03684 - 2-Methyl-2,4-Pentanediol
    DB03721 - O-Sialic Acid
    DB03965 - Fucose
    DB06779 inhibitor Dalteparin Anticoagulants;Antithrombotics;Heparins
    DB08813 inhibitor Nadroparin Anticoagulants;Antithrombotics
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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