Annotation Detail for SEMG2
Basic Information Top
| Gene Symbol: | SEMG2 ( SGII ) |
|---|---|
| Gene Full Name: | semenogelin II |
| Band: | 20q13.12 |
| Quick Links | Entrez ID:6407; OMIM: 182141; Uniprot ID:SEMG2_HUMAN; ENSEMBL ID: ENSG00000124157; HGNC ID: 10743 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D016264 | Dextran Sulfate | Dextran Sulfate affects the reaction [SEMG2 protein binds to KLK3 protein] | affects binding|affects reaction | 17253189 |
| D016264 | Dextran Sulfate | Dextran Sulfate affects the reaction [SEMG2 protein binds to SERPINA5 protein] | affects binding|affects reaction | 17253189 |
| D015032 | Zinc | SEMG2 protein inhibits the reaction [Zinc results in decreased activity of KLK5 protein] | decreases activity|decreases reaction | 16517595 |
| D015032 | Zinc | Zinc affects the reaction [SEMG2 protein binds to KLK3 protein] | affects binding|affects reaction | 17253189 |
| D015032 | Zinc | Zinc affects the reaction [SEMG2 protein binds to SERPINA5 protein] | affects binding|affects reaction | 17253189 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000169 | Acrodermatitis | Zinc | 6.29 | 16889938 17190629 17202136 | |
| MESH:D000544 | Alzheimer Disease | Zinc | 2.83 | 16580781 16325427 17119284 16410023 | |
| MESH:D000755 | Anemia, Sickle Cell | Zinc | 5.58 | 16916123 | |
| MESH:D001249 | Asthma | Zinc | 3.06 | 17085522 | |
| MESH:D001930 | Brain Injuries | Zinc | 5.45 | 17109824 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Zinc | 3.00 | 16543248 | |
| MESH:D002318 | Cardiovascular Diseases | Zinc | 3.98 | 16936243 | |
| MESH:D003092 | Colitis | Dextran Sulfate | 6.37 | 16375993 15652231 12065299 18023891 | |
| MESH:D019465 | Craniofacial Abnormalities | Zinc | 2.44 | 19302082 | |
| MESH:D003920 | Diabetes Mellitus | Zinc | 4.67 | 16479319 | |
| MESH:D004938 | Esophageal Neoplasms | Zinc | 2.95 | 16543248 | |
| MESH:D005756 | Gastritis | Zinc | 5.87 | 17241300 | |
| MESH:D006130 | Growth Disorders | Zinc | 4.25 | 17217573 | |
| MESH:D006333 | Heart Failure | Zinc | 3.88 | 17162251 | |
| MESH:D006335 | Heart Injuries | Zinc | 6.84 | 17074742 | |
| MESH:D016481 | Helicobacter Infections | Zinc | 5.14 | 17241300 | |
| MESH:D006527 | Hepatolenticular Degeneration | Zinc | 5.45 | 17276780 | |
| MESH:D015212 | Inflammatory Bowel Diseases | Dextran Sulfate | 4.79 | 20423518 15339030 | |
| MESH:D007511 | Ischemia | Zinc | 5.39 | 16584753 | |
| MESH:D007674 | Kidney Diseases | Zinc | 3.56 | 16960431 | |
| MESH:D007676 | Kidney Failure, Chronic | Zinc | 4.97 | 16518626 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Zinc | 3.58 | 12773700 | |
| MESH:D011225 | Pre-Eclampsia | Zinc | 4.56 | 17114810 | |
| MESH:D011471 | Prostatic Neoplasms | Zinc | 3.75 | 16700911 16606632 16517595 12429649 | |
| MESH:D012162 | Retinal Degeneration | Zinc | 4.49 | 16584753 | |
| MESH:D014062 | Tongue Neoplasms | Zinc | 4.90 | 16543248 |
| No data |