AutismKB 2.0

Annotation Detail for MAP2K4


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Basic Information Top
Gene Symbol:MAP2K4 ( JNKK,JNKK1,MAPKK4,MEK4,MKK4,PRKMK4,SEK1,SERK1 )
Gene Full Name: mitogen-activated protein kinase kinase 4
Band: 17p12
Quick LinksEntrez ID:6416; OMIM: 601335; Uniprot ID:MP2K4_HUMAN; ENSEMBL ID: ENSG00000065559; HGNC ID: 6844
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04912GnRH signaling pathway
hsa04012ErbB signaling pathway
hsa04010MAPK signaling pathway
hsa05142Chagas disease
hsa05120Epithelial cell signaling in Helicobacter pylori infection
hsa04620Toll-like receptor signaling pathway
hsa04664Fc epsilon RI signaling pathway
Pathway IDPathway Name
Signaling in Immune system
Pathway IDPathway Name
200031CD40/CD40L signaling
200188VEGFR3 signaling in lymphatic endothelium
200032Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
200003Fc-epsilon receptor I signaling in mast cells
200007RhoA signaling pathway
200129JNK signaling in the CD4+ TCR pathway
200132Nephrin/Neph1 signaling in the kidney podocyte
200124IL6-mediated signaling events
200173Ephrin B reverse signaling
200179Cellular roles of Anthrax toxin
200113ErbB1 downstream signaling
200100Ceramide signaling pathway
200102Regulation of Androgen receptor activity
200192Signaling events mediated by focal adhesion kinase
200190RAC1 signaling pathway
200057CDC42 signaling events
200056TRAIL signaling pathway
200054Regulation of p38-alpha and p38-beta
Pathway IDPathway Name
P00046Oxidative stress response
P00018EGF receptor signaling pathway
P00005Angiogenesis
P00020FAS signaling pathway
P00029Huntington disease
P00021FGF signaling pathway
P00034Integrin signalling pathway
P04393Ras Pathway
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1781Rheumatoid arthritis
1934Cancer
2206Sicca syndrome
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C439285 (5-fluoro-2-methyl-1-(4-pyridyl)methylene-3-(N-benzyl)-indene)-acetamide hydrochloride (5-fluoro-2-methyl-1-(4-pyridyl)methylene-3-(N-benzyl)-indene)-acetamide hydrochloride results in increased phosphorylation of and results in increased activity of MAP2K4 proteinincreases activity|increases phosphorylation 11051267
D000082 Acetaminophen Acetaminophen affects the expression of MAP2K4 mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen results in increased phosphorylation of and results in increased activity of MAP2K4 proteinincreases activity|increases phosphorylation 11562448
C037554 antimony trioxide MAP2K4 protein affects the reaction [antimony trioxide results in increased activity of MAPK8 protein]affects reaction|increases activity 16112521
C006632 arsenic trioxide MAP2K4 protein promotes the reaction [arsenic trioxide results in increased expression of HSPA6 mRNA]increases expression|increases reaction 15978632
C006632 arsenic trioxide MAP2K4 protein promotes the reaction [arsenic trioxide results in increased expression of HSPA6 protein]increases expression|increases reaction 15978632
C006632 arsenic trioxide MAP2K4 protein promotes the reaction [arsenic trioxide results in increased phosphorylation of HSF1 protein]increases phosphorylation|increases reaction 15978632
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of MAP2K4 mRNAdecreases expression 19150397
D002083 Butylated Hydroxyanisole Butylated Hydroxyanisole inhibits the reaction [Fenretinide results in increased phosphorylation of MAP2K4 protein]decreases reaction|increases phosphorylation 16407847
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased phosphorylation of MAP2K4 proteinincreases phosphorylation 17003459
D002726 Chlorogenic Acid Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAP2K4 protein]decreases reaction|increases phosphorylation 15944151
D003474 Curcumin Curcumin results in decreased expression of MAP2K4 mRNAdecreases expression 15713895
D003609 Dactinomycin Dactinomycin results in decreased expression of MAP2K4 mRNAdecreases expression 16001973
C042577 diallyl trisulfide MAP2K4 protein affects the reaction [diallyl trisulfide results in increased abundance of Reactive Oxygen Species]affects reaction|increases abundance 16707465
C042577 diallyl trisulfide MAP2K4 protein affects the reaction [diallyl trisulfide results in increased degradation of FTL protein]affects reaction|increases degradation 16707465
D004052 Diethylnitrosamine Diethylnitrosamine results in increased phosphorylation of and results in increased activity of MAP2K4 proteinincreases activity|increases phosphorylation 18691550
D004052 Diethylnitrosamine MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of and results in increased activity of MAP2K4 protein]decreases reaction|increases activity|increases phosphorylation 18691550
D004317 Doxorubicin Doxorubicin affects the activity of MAP2K4 proteinaffects activity 15870702
D004317 Doxorubicin Doxorubicin results in increased expression of MAP2K4 mRNAincreases expression 16001973
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of MAP2K4 mRNAincreases expression 17606305
C007845 gingerol gingerol inhibits the reaction [TNF protein results in increased phosphorylation of MAP2K4 protein]decreases reaction|increases phosphorylation 18577375
D017313 Fenretinide Butylated Hydroxyanisole inhibits the reaction [Fenretinide results in increased phosphorylation of MAP2K4 protein]decreases reaction|increases phosphorylation 16407847
D017313 Fenretinide Fenretinide results in increased phosphorylation of MAP2K4 proteinincreases phosphorylation 16407847
D006861 Hydrogen Peroxide MAP2K4 protein affects the reaction [Hydrogen Peroxide results in increased degradation of FTL protein]affects reaction|increases degradation 16707465
D007213 Indomethacin Indomethacin results in increased expression of MAP2K4 proteinincreases expression 15804060
C015329 lycopene lycopene results in decreased expression of MAP2K4 proteindecreases expression 17337101
D009151 Mustard Gas Mustard Gas results in increased phosphorylation of MAP2K4 proteinincreases phosphorylation 18200059
D011794 Quercetin Quercetin results in decreased expression of MAP2K4 mRNAdecreases expression 15309432
D011794 Quercetin Quercetin results in increased expression of MAP2K4 mRNAincreases expression 17103110
D017382 Reactive Oxygen Species MAP2K4 protein affects the reaction [diallyl trisulfide results in increased abundance of Reactive Oxygen Species]affects reaction|increases abundance 16707465
C017947 sodium arsenite sodium arsenite results in increased expression of MAP2K4 mRNAincreases expression 12760830
C025463 sulindac sulfone sulindac sulfone results in increased phosphorylation of and results in increased activity of MAP2K4 proteinincreases activity|increases phosphorylation 11051267
D013629 Tamoxifen Tamoxifen results in increased expression of MAP2K4 mRNAincreases expression 15590111
D013755 Tetradecanoylphorbol Acetate Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAP2K4 protein]decreases reaction|increases phosphorylation 15944151
D014028 Tobacco Smoke Pollution Tobacco Smoke Pollution results in increased expression of MAP2K4 mRNAincreases expression 15289447
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.3214745880
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.7117505938
MESH:D000230 Adenocarcinoma arsenic trioxide 12.9319825857 11798837
MESH:D000230 Adenocarcinoma Doxorubicin 12.9317418594
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 12.9314692618
MESH:D000230 Adenocarcinoma Fenretinide 12.9310697514
MESH:D000230 Adenocarcinoma Indomethacin 12.9316537180
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Tobacco Smoke Pollution 5.3015814487
MESH:D000236 Adenoma Diethylnitrosamine 6.496695378 10737359
MESH:D000236 Adenoma Indomethacin 6.4911497255
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 3.6719061943 17162532 19052882 18056438 17620307 16434500
MESH:D011125 Adenomatous Polyposis Coli sulindac sulfone 5.0916150858
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.4715276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.6716712894 17306315
MESH:D000419 Albuminuria Doxorubicin 4.3221441931
MESH:D019973 Alcohol-Related Disorders Curcumin 4.8517887948
MESH:D016301 Alveolar Bone Loss Indomethacin 5.1417225004
MESH:D000544 Alzheimer Disease Curcumin 4.3215590663
MESH:D000544 Alzheimer Disease Indomethacin 4.3217627676 15579461
MESH:D000743 Anemia, Hemolytic Quercetin 4.0317084956
MESH:D000799 Angioedema Acetaminophen 3.6110982225
MESH:D001014 Aortic Aneurysm Indomethacin 4.6310231640
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 4.6510388637
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.2411256880
MESH:D018771 Arthralgia Indomethacin 4.942160914
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.5315885639
MESH:D001172 Arthritis, Rheumatoid Curcumin 7.2916807698
MESH:D001172 Arthritis, Rheumatoid Indomethacin 7.2911248219
MESH:D001172 Arthritis, Rheumatoid Tobacco Smoke Pollution 7.2919898480
MESH:D001249 Asthma Mustard Gas 2.6410378619
MESH:D001260 Ataxia Telangiectasia Quercetin 4.7515336622
MESH:D050197 Atherosclerosis Curcumin 3.1918704882
MESH:D001321 Autistic Disorder Acetaminophen 1.4418445737
MESH:D001327 Autoimmune Diseases Curcumin 10.1219761891
MESH:D001327 Autoimmune Diseases Quercetin 10.1219761891
MESH:D001477 Bartter Syndrome Indomethacin 4.7610684365
MESH:D001768 Blister Mustard Gas 4.9319167455
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 3.4716206674
MESH:D019046 Bone Marrow Neoplasms Dactinomycin 11.5214601052
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 11.5214601052
MESH:D001929 Brain Edema Indomethacin 4.7911481608
MESH:D002545 Brain Ischemia Curcumin 9.6116770732
MESH:D002545 Brain Ischemia Indomethacin 9.6112524144
MESH:D001932 Brain Neoplasms Curcumin 13.6417596214
MESH:D001932 Brain Neoplasms Doxorubicin 13.6417150277
MESH:D001932 Brain Neoplasms Fenretinide 13.6416187019
MESH:D001943 Breast Neoplasms Curcumin 4.5516243823 19250217 18462866 18593918
MESH:D001943 Breast Neoplasms Diethylnitrosamine 4.5517474063
MESH:D001943 Breast Neoplasms Doxorubicin 4.5516935488 15994142 17983394 16322301 15634643 15939500 17369602 19526202 16595493 18628466 18234424 15692762 16115903 16264153 15567936 15993339 15668708 16096432 17426702 15136595 18382427 16826403 11325840 18695136
MESH:D001943 Breast Neoplasms Fenretinide 4.5516601279
MESH:D001943 Breast Neoplasms gingerol 4.5517683926
MESH:D001943 Breast Neoplasms Indomethacin 4.5517401462
MESH:D001943 Breast Neoplasms Quercetin 4.5518628248
MESH:D001943 Breast Neoplasms Tamoxifen 4.5518815881 20859285 17893378 18425577 20135344 19059307 19189210 17261762 15565566 19289846 19189212 21138602 19115204 16273361 19142967 19200415 19084267 18629630 19155303 17440819 15668708 18821012 16202921 19288272 11161223 18984771 19011961 19487384 18351453 19103187 20544844 19066611 16873071 17049068 19221464 20065188 18855134 21152245 19244106 17242785 18997820 20390343 16818667 20005174 19410462
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.9315286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.7517687719 10378619
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.1211589617
MESH:D002056 Burns Indomethacin 4.4810459503
MESH:D002100 Cachexia Indomethacin 4.7815141370 16537180 11239499 15625704
MESH:D002105 Cadmium Poisoning Quercetin 5.3116962696
MESH:D002276 Carcinoid Tumor Doxorubicin 4.5816051944
MESH:D002277 Carcinoma Curcumin 3.6618593918
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.2819066611
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 19.163084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 19.1615553829 11135700 16217749 15073043 14691202
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 19.1616830150 17138121 18978308 19171122 19418558 19052882 20007298 20214788 16681979 17978847 19335982 18210153 16807293 16935385 16779866 19701751 20432363 16328049 18494052 19539802 19919837 3084413 18691550 20514400 3581430 20727157 18056438 11831363 19383236 17173139 20084675 18506893 19519916 18393292 17162532 10672840 18665156 16569478 19394651 16288022 19822196 16502159 20101231 19208518 19107877 17055752 16698587 17761372 16540662 20935162 21159647 17428255 18971187 18785209 16878318 20524982 10737359 20512989 18788625
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 19.1618059187 16023760 16234567 17876044
MESH:D006528 Carcinoma, Hepatocellular Fenretinide 19.1617159502 16270382
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 19.1616391822
MESH:D006528 Carcinoma, Hepatocellular Quercetin 19.1612508355 19519916
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 19.1617306315 15276417 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 19.1616924424
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 4.5011053908
MESH:D018276 Carcinoma, Medullary Indomethacin 5.1211352223 14736730 18791128
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 8.8018414057
MESH:D002289 Carcinoma, Non-Small-Cell Lung sulindac sulfone 8.8018758305
MESH:D002289 Carcinoma, Non-Small-Cell Lung Tobacco Smoke Pollution 8.8011212258
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.7317234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.6419014326
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 6.4516201981 1485588
MESH:D002292 Carcinoma, Renal Cell Indomethacin 6.4517341418
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.9212490120
MESH:D002294 Carcinoma, Squamous Cell Curcumin 20.9718462866
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 20.976189445
MESH:D002294 Carcinoma, Squamous Cell Fenretinide 20.9716274795
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 20.9715482327 12636206
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 20.9718572023
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 20.9718922899
MESH:D002294 Carcinoma, Squamous Cell Tobacco Smoke Pollution 20.9711212258
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.4217572228
MESH:D006332 Cardiomegaly Quercetin 3.1919794523
MESH:D009202 Cardiomyopathies Doxorubicin 3.3817928571 16364871 17007740 18627295 15811867 16651473 16242529 15476868 17974986 17131338 17329180 15505089 16612575 16269455 17924179 17351982 16952015 17382496 15792986 16109756 16455267 16731534 16278810 17519947 17308081
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.8717334414 16243910
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 3.3616936243
MESH:D002386 Cataract Acetaminophen 2.4510977129
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 10.3120889678
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 10.3117174075 21159647 2727394 7505956
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 10.3120056578 19524636
MESH:D018290 Cervical Intraepithelial Neoplasia Fenretinide 5.2516154183
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.4919052882
MESH:D002764 Cholecystitis Indomethacin 4.9411181007
MESH:D002779 Cholestasis Ethinyl Estradiol 2.7116105132 11677210 17681005 17110522 16919318 17333356 15861022
MESH:D003092 Colitis Curcumin 3.9516782535 18200517 16804969
MESH:D003103 Coloboma Curcumin 4.3418809619
MESH:D003110 Colonic Neoplasms Curcumin 5.7119359593 16340194
MESH:D003110 Colonic Neoplasms Indomethacin 5.7115963497 15936596 15625704 11260862 15786552 15637740
MESH:D003110 Colonic Neoplasms Quercetin 5.7116640504 19440933 11134977 17191121 19056647 15741050 17148506
MESH:D015179 Colorectal Neoplasms arsenic trioxide 8.1120501625
MESH:D015179 Colorectal Neoplasms Doxorubicin 8.1118802399 18259882
MESH:D015179 Colorectal Neoplasms Fenretinide 8.1117273769
MESH:D015179 Colorectal Neoplasms Indomethacin 8.1118059344 12606626 11197048 17054584
MESH:D015179 Colorectal Neoplasms Quercetin 8.1118852136 18095365
MESH:D015179 Colorectal Neoplasms sulindac sulfone 8.1110416599 18059344 10666051 11197048
MESH:D016510 Corneal Neovascularization Curcumin 4.6718497527
MESH:D023903 Coronary Restenosis arsenic trioxide 3.9712609071
MESH:D018352 Coronavirus Infections Indomethacin 5.4917302372
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.0610525206
MESH:D019465 Craniofacial Abnormalities Reactive Oxygen Species 3.0615736158
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.8815213294
MESH:D003711 Demyelinating Diseases Tamoxifen 4.1419031437
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.5519496084
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 4.4118403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.4120387270
MESH:D003928 Diabetic Nephropathies Curcumin 8.4218204486
MESH:D003928 Diabetic Nephropathies Tamoxifen 8.4219279558
MESH:D003967 Diarrhea Indomethacin 3.587237001 7907874
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 5.8418071297 16393943 16109766 18713872 17906064 19923254 19739265 12153990 10915739 10774834 11287661 12392966 16081117 10663392 14986274 11743745 16177239 16485898 19416960 12540782 19085960 15619225 16781746 11529661 14725611 17562736 11461765 11739529 12705907 19164858 11834606 12594235 12958197 19420014 16227642 14550746 17522070 2444490 15968718 19370779 11421492
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 5.8419107877
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 5.8417416283
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.8719426721
MESH:D004362 Drug Toxicity Doxorubicin 3.5018602426
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 4.9218043480 16326151 12774134 17190690 16133044 18446180
MESH:D004381 Duodenal Ulcer Curcumin 8.6917351913
MESH:D004381 Duodenal Ulcer Indomethacin 8.6911535926 16699067 17045617 17351913 10671773 11991626 17329845 11595415 17151854 17202747 11595431
MESH:D004487 Edema Indomethacin 10.5516100529 10653021 7907874 19703484 7990266 8273558 8985016
MESH:D004487 Edema Mustard Gas 10.5511402378 9260866 11428647 11428631
MESH:D004487 Edema Tetradecanoylphorbol Acetate 10.5511698051 7812673 15177302 8113982 16716910 8273558 9599246
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.2212538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 8.2219031437
MESH:D016889 Endometrial Neoplasms Doxorubicin 7.0717359293
MESH:D016889 Endometrial Neoplasms Tamoxifen 7.0717893378 19155303 16202921 20544844
MESH:D004715 Endometriosis Indomethacin 3.9515652904
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.9318037988
MESH:D019446 Endotoxemia Indomethacin 4.2718509659
MESH:D004751 Enteritis Indomethacin 4.5210567023 16328016 17763956
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 4.7617980183
MESH:D004802 Eosinophilia Indomethacin 3.8311298111
MESH:D004890 Erythema Mustard Gas 4.939357497
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.8916302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 6.9620426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 6.9612903497
MESH:D004938 Esophageal Neoplasms Indomethacin 6.9611005569
MESH:D005234 Fatty Liver arsenic trioxide 22.4715073043
MESH:D005234 Fatty Liver Curcumin 22.4719297423
MESH:D005234 Fatty Liver Diethylnitrosamine 22.4720387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 22.4715345470
MESH:D005234 Fatty Liver Tamoxifen 22.4719224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.1016709447
MESH:D005334 Fever Indomethacin 3.9211852909 17627676 10431976
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.3014745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 10.6819069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 10.6819069698
MESH:D005354 Fibrosarcoma Indomethacin 4.6610962813
MESH:D005355 Fibrosis Curcumin 13.7318705752
MESH:D005355 Fibrosis Indomethacin 13.7317994277
MESH:D005355 Fibrosis Quercetin 13.7319474275
MESH:D005499 Folliculitis Indomethacin 4.9411298111
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.0416904648
MESH:D005756 Gastritis Acetaminophen 10.3816983495
MESH:D005756 Gastritis Indomethacin 10.3815046732
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.4718462866
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.4516452187
MESH:D005909 Glioblastoma Curcumin 20.7217596214
MESH:D005909 Glioblastoma Doxorubicin 20.7217150277
MESH:D005909 Glioblastoma Fenretinide 20.7216187019
MESH:D005909 Glioblastoma Indomethacin 20.7212870263
MESH:D005909 Glioblastoma Quercetin 20.7219804834
MESH:D005910 Glioma Indomethacin 6.0218371953 16487511
MESH:D005910 Glioma Quercetin 6.0217643826
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 4.1011849393
MESH:D006073 Gout Indomethacin 5.1211248219
MESH:D006258 Head and Neck Neoplasms Curcumin 12.2118829502 18462866
MESH:D006258 Head and Neck Neoplasms Doxorubicin 12.2115692506
MESH:D006258 Head and Neck Neoplasms Indomethacin 12.2115482327
MESH:D006331 Heart Diseases Doxorubicin 3.3317875725 12587719 16244372 16879835 16495754 16707910 14766674 16144979 18006777 17888722 16244371 16330681 18674790
MESH:D006333 Heart Failure Doxorubicin 3.2017481944
MESH:D006394 Hemangiosarcoma Doxorubicin 3.7015692506
MESH:D006501 Hepatic Encephalopathy Indomethacin 4.3615633222
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.4615135802
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.8117701891
MESH:D006689 Hodgkin Disease Doxorubicin 6.8515147373 18501091 17606976
MESH:D006689 Hodgkin Disease sodium arsenite 6.8512676792
MESH:D006930 Hyperalgesia Acetaminophen 7.2416870215
MESH:D006930 Hyperalgesia Indomethacin 7.2412727271
MESH:D034321 Hyperamylasemia Indomethacin 5.4917883296
MESH:D006937 Hypercholesterolemia Curcumin 3.8518704882
MESH:D006940 Hyperemia Indomethacin 4.7812524144
MESH:D006943 Hyperglycemia Quercetin 3.8318262572 11834736
MESH:D006949 Hyperlipidemias Indomethacin 3.9517546600
MESH:D006973 Hypertension Quercetin 2.7718356687
MESH:D007021 Hypospadias Ethinyl Estradiol 3.5816569931 16945680
MESH:D007077 Ileal Diseases Indomethacin 4.7918306037 10574470
MESH:D007079 Ileitis Indomethacin 5.1210651667 10647630 16133968
MESH:D007235 Infant, Premature, Diseases Indomethacin 5.1416133044
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.2512013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.1417937319
MESH:D007248 Infertility, Male sodium arsenite 6.1412646999 15346721
MESH:D007249 Inflammation Curcumin 22.4516956363 18403477 17151092
MESH:D007249 Inflammation Diethylnitrosamine 22.4518785209
MESH:D007249 Inflammation Indomethacin 22.453291741 12568917 7812673
MESH:D007249 Inflammation Mustard Gas 22.458975870 11428631 11428647 9357497 11402378 17524151 9260866 16001271 11428620
MESH:D007249 Inflammation Tamoxifen 22.4519457130
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 22.458273558 15177302 7812673 7562506 11698051
MESH:D007249 Inflammation Tobacco Smoke Pollution 22.4518590791
MESH:D015212 Inflammatory Bowel Diseases Curcumin 3.1218596194 18200517
MESH:D007251 Influenza, Human Quercetin 4.2816624496
MESH:D007410 Intestinal Diseases Indomethacin 4.1011713966 10210152 17994277 11686837 17329856 11855677 15610444 15831440 18236018
MESH:D007414 Intestinal Neoplasms Curcumin 4.0210783313
MESH:D002532 Intracranial Aneurysm Reactive Oxygen Species 4.7619381132
MESH:D019586 Intracranial Hypertension Indomethacin 5.1415241188
MESH:D007579 Jejunal Diseases Indomethacin 4.7916133968 10574470 18306037
MESH:D007627 Keloid Quercetin 4.7317086741
MESH:D007674 Kidney Diseases Acetaminophen 17.6915629191 12587719
MESH:D007674 Kidney Diseases Doxorubicin 17.6916775033 15699352 15369732
MESH:D007674 Kidney Diseases Indomethacin 17.6917190690
MESH:D007674 Kidney Diseases Quercetin 17.6916962696
MESH:D007674 Kidney Diseases sodium arsenite 17.6920008137
MESH:D007676 Kidney Failure, Chronic Doxorubicin 9.4416707910
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 9.4416518626
MESH:D007680 Kidney Neoplasms Tamoxifen 2.8618625569
MESH:D007889 Leiomyoma Curcumin 4.3618555241
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.7211703811 12228301 10320625
MESH:D007938 Leukemia arsenic trioxide 9.9215070760
MESH:D007938 Leukemia Curcumin 9.9218462866
MESH:D007938 Leukemia Quercetin 9.9217468513
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.9316085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 9.0817077332 12560223
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 9.0816106398
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.0816972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 8.0014633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 8.0010785260 16572323 15631656
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.5619077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.9417050201 16467208 19850784 20471514 16968895
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 3.9418360721
MESH:D015473 Leukemia, Promyelocytic, Acute antimony trioxide 8.039834237
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 8.0316891316 17217047 12712474 12679006 17649720 15336539 17712046 16330433 11468182 16331271 17869043 16966277 15213294 11161223 15622746 19642359 9834237 17107899 19075265 15748426 19035177 12018890 16823087 19225113 16112521
MESH:D015458 Leukemia, T-Cell arsenic trioxide 10.9816882451
MESH:D015458 Leukemia, T-Cell Curcumin 10.9816106398
MESH:D007964 Leukocytosis Indomethacin 5.1416537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.4917980183
MESH:D007972 Leukoplakia, Oral Fenretinide 5.8116707609
MESH:D008064 Lipidoses Tamoxifen 2.9917567588 15342952
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.4911479899
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.7018665156 20032147 18407596 18522880 19638242
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 6.4618705752 18006644 17355460
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 6.4616595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 6.4618194892
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 6.4612741479
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 6.4618564211
MESH:D008107 Liver Diseases Acetaminophen 6.1819784758 11587558 12587719 16611625 19460945 16610002 19014921 12969438
MESH:D008107 Liver Diseases Curcumin 6.1816956363
MESH:D008107 Liver Diseases Diethylnitrosamine 6.1817034775
MESH:D017114 Liver Failure, Acute Acetaminophen 3.0417185352 16871587
MESH:D008113 Liver Neoplasms arsenic trioxide 13.3214682389
MESH:D008113 Liver Neoplasms Diethylnitrosamine 13.3219254457 21047994 18648771 19996281 18977376 21071580 20452335 21167192 19294768 16942905 19812893 15885732 19426721 19642983 19499222 20118626 20137499 19850985 21278145 20492335 20101389 10737359 18644402 19073162 12771043 2422723 19690152 2862719 15175105 20405173 19638242 20434301 12112319 19090486 18754104 18978307 9163691 19427195 19256749 19833225 20583210 19551842 20501860 19255062
MESH:D008113 Liver Neoplasms Quercetin 13.3218980244
MESH:D008113 Liver Neoplasms sodium arsenite 13.3215276417 16712894
MESH:D008113 Liver Neoplasms Tamoxifen 13.3216684651
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 13.0220377131
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 13.023124819 18079962 21159647 19009564 18308698 18544905 19126423 18164116 2563599 18775883 19539802 18253720 19004024 17854601 9362446 17942915 16842330 18282651 18093689 16267830 17174075 19519916
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 13.0217085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Quercetin 13.0219519916
MESH:D008133 Long QT Syndrome arsenic trioxide 3.1815213294
MESH:D008171 Lung Diseases Mustard Gas 7.0418702808 18161513
MESH:D008171 Lung Diseases sodium arsenite 7.0419095001
MESH:D008175 Lung Neoplasms arsenic trioxide 19.9211798837 19825857
MESH:D008175 Lung Neoplasms Curcumin 19.9219359593 18462866 16243823
MESH:D008175 Lung Neoplasms Diethylnitrosamine 19.9221163286 20970405 6695378 20512841
MESH:D008175 Lung Neoplasms Doxorubicin 19.926189445 17418594
MESH:D008175 Lung Neoplasms Indomethacin 19.9211497255 11053908 16537180
MESH:D008175 Lung Neoplasms Mustard Gas 19.923148597 8781369
MESH:D008175 Lung Neoplasms Quercetin 19.9216280456
MESH:D008175 Lung Neoplasms sodium arsenite 19.9217306315 15276417 16712894 19931552 17077188
MESH:D008175 Lung Neoplasms Tamoxifen 19.9218625569
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 19.9211807781
MESH:D008175 Lung Neoplasms Tobacco Smoke Pollution 19.9212111688 3440675 11091918 16288123
MESH:D008223 Lymphoma Curcumin 7.2518462866
MESH:D008223 Lymphoma Doxorubicin 7.2516098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.6117654614
MESH:D016399 Lymphoma, T-Cell Curcumin 10.8116173963
MESH:D016399 Lymphoma, T-Cell Doxorubicin 10.8115621674
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.5319428831
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 13.1615458769
MESH:D008325 Mammary Neoplasms, Experimental Fenretinide 13.1610697514
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 13.1611731420 16827153 14580682 19196722 19196723
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 13.168985016
MESH:D020149 Manganese Poisoning Tamoxifen 4.3219453300
MESH:D008545 Melanoma Curcumin 11.9818462866 17885582
MESH:D008545 Melanoma Doxorubicin 11.9816827129
MESH:D008545 Melanoma Fenretinide 11.9816270382
MESH:D008545 Melanoma Reactive Oxygen Species 11.9817992120
MESH:D008545 Melanoma sodium arsenite 11.9816487513 19082730
MESH:D008545 Melanoma Tamoxifen 11.9812393984 19393235
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.9515990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.3419513568
MESH:D008569 Memory Disorders Curcumin 3.9417263510
MESH:D008654 Mesothelioma Doxorubicin 2.9717638057
MESH:D008881 Migraine Disorders Indomethacin 3.5111903285
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.2915792986
MESH:D009062 Mouth Neoplasms Fenretinide 13.6716274795
MESH:D009062 Mouth Neoplasms Indomethacin 13.6712636206
MESH:D009062 Mouth Neoplasms Tobacco Smoke Pollution 13.6715006635
MESH:D052016 Mucositis Doxorubicin 4.5617415656
MESH:D009101 Multiple Myeloma arsenic trioxide 6.9119549372 19417148 15949261 11468182 14977855
MESH:D009101 Multiple Myeloma Curcumin 6.9119372569
MESH:D009134 Muscular Atrophy, Spinal Curcumin 4.6917962980
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.4418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.0116882451 16105982
MESH:D009203 Myocardial Infarction Doxorubicin 5.7119429709 15857846
MESH:D009203 Myocardial Infarction Quercetin 5.7119595682
MESH:D015428 Myocardial Reperfusion Injury Quercetin 3.6219207477
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 9.6016624393
MESH:D009361 Neoplasm Invasiveness Curcumin 9.6018495463
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 12.869029167 3581430
MESH:D009362 Neoplasm Metastasis Doxorubicin 12.8618259882
MESH:D009362 Neoplasm Metastasis Indomethacin 12.8611239499 16537180 11053908
MESH:D009362 Neoplasm Metastasis Tamoxifen 12.8619393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4419410462
MESH:D009369 Neoplasms Fenretinide 11.0717353921 15958647
MESH:D009369 Neoplasms lycopene 11.0717051425
MESH:D009369 Neoplasms Quercetin 11.0715185748
MESH:D009369 Neoplasms sodium arsenite 11.0711559025
MESH:D009374 Neoplasms, Experimental Indomethacin 8.5315625704 10663608
MESH:D009374 Neoplasms, Experimental sodium arsenite 8.5320056578
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 10.0712497104
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 10.0719189210 19200415 19196722
MESH:D009401 Nephrosis Doxorubicin 4.5416899518 16636307
MESH:D009404 Nephrotic Syndrome Doxorubicin 3.8115640375 16889571
MESH:D009423 Nervous System Neoplasms Curcumin 5.4018462866
MESH:D009436 Neural Tube Defects arsenic trioxide 6.8510525206
MESH:D009436 Neural Tube Defects sodium arsenite 6.8512854658
MESH:D009447 Neuroblastoma Doxorubicin 3.1515555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 13.0018514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 13.0020387270
MESH:D019636 Neurodegenerative Diseases Indomethacin 13.0012349958
MESH:D020078 Neurogenic Inflammation Quercetin 4.1517929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.8920387270
MESH:D009472 Neuronal Ceroid-Lipofuscinoses Fenretinide 5.4516303764
MESH:D009503 Neutropenia Mustard Gas 3.7616761898 7688884
MESH:D009765 Obesity Curcumin 2.6919297423
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.946374098
MESH:D010003 Osteoarthritis Indomethacin 3.537009135
MESH:D010024 Osteoporosis Curcumin 3.3318719352
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 4.0119495926
MESH:D012516 Osteosarcoma Doxorubicin 3.9315930896
MESH:D010051 Ovarian Neoplasms arsenic trioxide 14.2219769630 16624393 12452020
MESH:D010051 Ovarian Neoplasms Curcumin 14.2219020741 18462866
MESH:D010051 Ovarian Neoplasms Fenretinide 14.2216133793
MESH:D010051 Ovarian Neoplasms Quercetin 14.2219005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 14.2217306315 15276417
MESH:D010146 Pain Acetaminophen 6.1916870215
MESH:D010146 Pain Indomethacin 6.1913679232 17627676 3291741 17440234
MESH:D010149 Pain, Postoperative Indomethacin 4.4518702446 12538197
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 23.6115580305
MESH:D010190 Pancreatic Neoplasms Curcumin 23.6117440100 19401701 19196508
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 23.6116540662
MESH:D010190 Pancreatic Neoplasms Fenretinide 23.6115580305
MESH:D010190 Pancreatic Neoplasms Quercetin 23.6116965848
MESH:D010190 Pancreatic Neoplasms Reactive Oxygen Species 23.6115580305
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 23.6115976015
MESH:D010195 Pancreatitis Indomethacin 3.7117883296 15028970
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.4711578682
MESH:D010212 Papilloma Hydrogen Peroxide 8.8712065085
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 8.8712065085 8330346 18922899 18404319
MESH:D010235 Paraganglioma arsenic trioxide 3.9519927285
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.4916537180
MESH:D020734 Parkinsonian Disorders Indomethacin 3.9212349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.4911903285
MESH:D010437 Peptic Ulcer Indomethacin 4.9211148446
MESH:D010518 Periodontitis Indomethacin 4.6817225004
MESH:D003557 Phyllodes Tumor Doxorubicin 4.9317983394
MESH:D010997 Pleural Neoplasms Doxorubicin 4.9317638057
MESH:D011041 Poisoning Mustard Gas 3.5915727166
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.592563599
MESH:D011230 Precancerous Conditions Quercetin 8.5919056647
MESH:D047928 Premature Birth Indomethacin 4.9017000239
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.4619131511
MESH:D011471 Prostatic Neoplasms Curcumin 3.4618226269 12497104 18769126 18156803 10851300 11398177 15129424
MESH:D011471 Prostatic Neoplasms diallyl trisulfide 3.4617513609
MESH:D011471 Prostatic Neoplasms Doxorubicin 3.4615897917 15749863 16729912 16888761 18437689 16868541
MESH:D011471 Prostatic Neoplasms Fenretinide 3.4617024972
MESH:D011471 Prostatic Neoplasms lycopene 3.4615084515 17337101
MESH:D011471 Prostatic Neoplasms Quercetin 3.4617292933 14715546
MESH:D011471 Prostatic Neoplasms sodium arsenite 3.4616039940
MESH:D011471 Prostatic Neoplasms sulindac sulfone 3.4617908994 15570007
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.4615067354
MESH:D011507 Proteinuria Indomethacin 3.9511849393
MESH:D011537 Pruritus Ethinyl Estradiol 8.7615861022 16919318
MESH:D011537 Pruritus Mustard Gas 8.7618058305
MESH:D011656 Pulmonary Emphysema Curcumin 4.3319168576
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.8417620002 17266442 10334151 17894541 17720292
MESH:D051437 Renal Insufficiency Doxorubicin 4.0017922066
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 3.8218379247 10666014
MESH:D012135 Respiratory Sounds Tobacco Smoke Pollution 4.4018410779
MESH:D012162 Retinal Degeneration Fenretinide 4.2316303925
MESH:D012509 Sarcoma Curcumin 8.9118462866
MESH:D012509 Sarcoma Doxorubicin 8.9115625365 17203757 15675481 17710206 18313854 16767912
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 16.1116646077
MESH:D012512 Sarcoma, Ewing's Dactinomycin 16.1114601052
MESH:D012512 Sarcoma, Ewing's Doxorubicin 16.1116326096 14601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.5617846226
MESH:D012554 Schistosomiasis japonica Quercetin 5.3116862918
MESH:D018805 Sepsis Curcumin 3.8918389075
MESH:D012871 Skin Diseases Mustard Gas 2.6612880345 16961503 15451306
MESH:D012878 Skin Neoplasms Doxorubicin 30.2215692506
MESH:D012878 Skin Neoplasms Fenretinide 30.2216467112
MESH:D012878 Skin Neoplasms gingerol 30.2219481070
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 30.2212065085
MESH:D012878 Skin Neoplasms sodium arsenite 30.2219524636 18572023
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 30.228532709
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 30.228330346 11807781 18404319 12065085 8985016
MESH:D012878 Skin Neoplasms Tobacco Smoke Pollution 30.2218590791
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.3416767912 17203757 15625365
MESH:D013088 Spermatocele Ethinyl Estradiol 10.7916709447
MESH:D013088 Spermatocele Tamoxifen 10.7916709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.8119457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.6212854658
MESH:D013272 Stomach Diseases Indomethacin 4.1910192188 17160473 17638125 10486359 17207306 10215738 16113693 15038085 16184426 18209964 16280098 15472012 18545984
MESH:D013274 Stomach Neoplasms arsenic trioxide 4.6217007042
MESH:D013274 Stomach Neoplasms Butylated Hydroxyanisole 4.621399818 3581430
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 4.6218456281
MESH:D013274 Stomach Neoplasms Indomethacin 4.6215609394
MESH:D013276 Stomach Ulcer Curcumin 6.9019188055 16631530
MESH:D013276 Stomach Ulcer Indomethacin 6.9017657623 10423059 16934674 10750652 11595431 17918041 15255614 15138204 11523592 12077510 11729361 17895592 18299717 11595415 12498302 18431645 12467913 11906479 18181030 1323529 18193104 16631530 11145282 15104355 18209962 17627676 16169175 17135157 14567935 16150113 12787963 16397915 17654042 17977527 18726076 16755016 18237397 18543354 18087811 10878458 16252198 12500499
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.4111994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.9615669648
MESH:D013964 Thyroid Neoplasms arsenic trioxide 15.7419014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 15.747505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 15.7416010429 17909728
MESH:D013964 Thyroid Neoplasms Indomethacin 15.7411352223 14736730 18791128
MESH:D016171 Torsades de Pointes arsenic trioxide 3.7315213294
MESH:D014456 Ulcer Indomethacin 4.6610574470 17380554
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 31.3412973940 20435036 11780464 12845720
MESH:D001749 Urinary Bladder Neoplasms Butylated Hydroxyanisole 31.341399818
MESH:D001749 Urinary Bladder Neoplasms Curcumin 31.3418593936
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 31.3417653716
MESH:D001749 Urinary Bladder Neoplasms Fenretinide 31.3416720286
MESH:D001749 Urinary Bladder Neoplasms Quercetin 31.3416720314
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 31.3416452187 17306315 11723127 16712894
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 31.3417572228 16712894 8653321
MESH:D001749 Urinary Bladder Neoplasms Tobacco Smoke Pollution 31.3412846360
MESH:D014565 Urogenital Neoplasms Curcumin 5.0318462866
MESH:D014581 Urticaria Acetaminophen 2.7710982225
MESH:D002583 Uterine Cervical Neoplasms Fenretinide 9.0816154183
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 9.0811813266
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.0814692618
MESH:D014652 Vascular Diseases sodium arsenite 4.2017056641
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.3315869587 14671159
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 4.0016364871 17334414 17638931 17678736
MESH:D014839 Vomiting Indomethacin 4.5211897121
Pathway ID Pathway Name
KEGG:05142 Chagas disease (American trypanosomiasis)
KEGG:05120 Epithelial cell signaling in Helicobacter pylori infection
KEGG:04012 ErbB signaling pathway
KEGG:04664 Fc epsilon RI signaling pathway
KEGG:04912 GnRH signaling pathway
KEGG:04010 MAPK signaling pathway
REACT:6900 Signaling in Immune system
KEGG:04620 Toll-like receptor signaling pathway
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA30589
    • No data
    Releated disease ID Related disease Name
    PA445062Neoplasms
    Releated drug ID Related drug Name
    PA449167cyclosporine
    PA451578tacrolimus
    PA449972imiquimod
    PA10804imatinib
    PA449780glutathione
    PA450635nitric oxide
    PA448948chloroquine
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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