AutismKB 2.0

Annotation Detail for SET


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Basic Information Top
Gene Symbol:SET ( 2PP2A,I2PP2A,IGAAD,IPP2A2,PHAPII,TAF-I,TAF-IBETA )
Gene Full Name: SET nuclear oncogene
Band: 9q34.11
Quick LinksEntrez ID:6418; OMIM: 600960; Uniprot ID:SET_HUMAN; ENSEMBL ID: ENSG00000119335; HGNC ID: 10760
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1831Prostate cancer
1887Carcinoma
2051Leukemia
2112Ovary cancer
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of SET mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of SET mRNAaffects expression 21346803
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of SET mRNAaffects expression 21346803
C006632 arsenic trioxide arsenic trioxide results in increased expression of SET mRNAincreases expression 20458559
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of SET mRNAincreases expression 19150397
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of SET mRNAaffects expression 17484886
C099555 CD 437 CD 437 results in decreased expression of SET mRNAdecreases expression 12958071
D002995 Clofibric Acid Clofibric Acid affects the expression of SET mRNAaffects expression 17602206
C014347 decitabine decitabine results in increased expression of SET proteinincreases expression 19294695
C014347 decitabine [trichostatin A co-treated with decitabine] results in increased expression of SET proteinaffects cotreatment|increases expression 19294695
D002117 Calcitriol Calcitriol results in decreased expression of SET mRNAdecreases expression 12798352
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of SET mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of SET mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SET mRNAaffects cotreatment|increases expression 17942748
D010269 Paraquat Paraquat affects the expression of SET mRNAaffects expression 15206577
D012402 Rotenone Rotenone results in decreased expression of SET mRNAdecreases expression 19013527
D012643 Selenium [Selenium co-treated with Vitamin E] results in decreased expression of SET mRNAaffects cotreatment|decreases expression 19244175
D013629 Tamoxifen Tamoxifen affects the expression of SET mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SET mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of SET mRNAincreases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of SET proteindecreases expression 16548065
C012589 trichostatin A [trichostatin A co-treated with decitabine] results in increased expression of SET proteinaffects cotreatment|increases expression 19294695
C012589 trichostatin A trichostatin A results in increased expression of SET proteinincreases expression 19294695
C025643 vinclozolin vinclozolin affects the expression of SET mRNAaffects expression 19015723
D014810 Vitamin E [Selenium co-treated with Vitamin E] results in decreased expression of SET mRNAaffects cotreatment|decreases expression 19244175
D014810 Vitamin E Vitamin E results in decreased expression of SET mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.4914745880
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 8.287525203
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.2814514962 15322242 11752688
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8917505938
MESH:D000230 Adenocarcinoma arsenic trioxide 4.2311798837 19825857
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.2314692618
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.3216835633
MESH:D000382 Agricultural Workers' Diseases Paraquat 3.7011874814
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8911748828
MESH:D001008 Anxiety Disorders vinclozolin 3.5819015723
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.4011256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6215885639
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 8.7516206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.7512125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7315340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7215746008
MESH:D001943 Breast Neoplasms Calcitriol 1.9511237771
MESH:D001943 Breast Neoplasms decitabine 1.9519208741 18320071
MESH:D001943 Breast Neoplasms Tamoxifen 1.9517440819 19289846 19066611 18425577 21138602 11161223 16873071 20005174 17261762 19059307 18821012 17893378 19410462 18815881 20390343 18984771 20859285 17242785 17049068 19115204 20065188 19189210 18997820 18855134 19200415 20135344 15668708 15565566 19084267 16202921 19288272 18351453 21152245 19103187 19244106 18629630 19011961 19142967 19487384 19155303 16818667 19189212 16273361 19221464 20544844
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9520435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.2711589617
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 9.7216097048 15700767 16011737 10355542 16124888 15673190 18705752 16050911 15721981 16227642 16192424 3786805
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 9.7216050911
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7416835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.4419066611
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 8.7616705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 8.7616705839
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 8.7616217749 11135700 15073043 15553829 14691202
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 8.7618788625
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 8.7616924424
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.8219014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.0612490120
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 4.8211237771
MESH:D002294 Carcinoma, Squamous Cell decitabine 4.8219215824
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.5517572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3316120746 18850075 18670907
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 3.5914694615
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 6.496135515
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 6.4920889678
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1016835633
MESH:D002779 Cholestasis Ethinyl Estradiol 2.8215861022 16919318 11677210 17110522 17681005 17333356 16105132
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0815340226 8697196 12621046 15668235 16354765
MESH:D003092 Colitis Selenium 3.7217936198
MESH:D003110 Colonic Neoplasms decitabine 2.3217616700
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.5720501625
MESH:D015179 Colorectal Neoplasms decitabine 2.5718981723
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 8.9915095906
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 8.9914669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 4.1212609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.7310525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.7310048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Vitamin E 3.7319769572
MESH:D003456 Cryptorchidism vinclozolin 4.2814966744
MESH:D003490 Cyanosis 2,4-dinitrotoluene 10.6818551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 10.6818551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.0315213294
MESH:D003711 Demyelinating Diseases Tamoxifen 4.3019031437
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6517107852
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.4219279558
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 15.0221346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 15.0218551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 15.0221346803
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 15.0216227642 3786805 15968718 15998439 19085960 4309450 7440962 19336974 16177239 9327722 2869522 17522070 6884620 15027814 10915739 7120509 10092053 7179309 21278145 6623471 11566570 3732212
MESH:D056486 Drug-Induced Liver Injury Selenium 15.0215131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 15.0220420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7111462148
MESH:C538011 Eales disease Vitamin E 4.659068938
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.3212711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.8515322242 16714409 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 14.9815138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 14.9812538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 14.9819031437
MESH:D004701 Endocrine Gland Neoplasms decitabine 13.8419294695
MESH:D004701 Endocrine Gland Neoplasms trichostatin A 13.8419294695
MESH:D016889 Endometrial Neoplasms Tamoxifen 3.0020544844 16202921 17893378 19155303
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.969294722 10568697
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.4020426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.4012903497
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9611564622
MESH:D005234 Fatty Liver arsenic trioxide 18.2715073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 18.2761145 17595544 15959796 16239168 16045604 19224547 12795759 12631006
MESH:D005234 Fatty Liver Ethinyl Estradiol 18.2715345470
MESH:D005234 Fatty Liver Tamoxifen 18.2714986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.1916709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3911858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.4714745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.1219069698
MESH:D005355 Fibrosis Carbon Tetrachloride 8.3918705752
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 8.3920067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.2016904648
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.8716973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.2416417039
MESH:D005909 Glioblastoma trichostatin A 3.7918801729
MESH:D005911 Gliosis Paraquat 5.1111124998
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5410696789
MESH:D006258 Head and Neck Neoplasms decitabine 3.4419215824
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.4511294989 10048152
MESH:D006330 Heart Defects, Congenital Vitamin E 6.4516080930
MESH:D006333 Heart Failure Selenium 3.0317162251
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2711000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.5319900420 19110552
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.8315340226 12621046 16120746
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.6816863852 16490937
MESH:D019584 Hot Flashes Vitamin E 3.9214716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.9918606429 15340226 16354765 16959395 8697196
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.4716899240
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.8818670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.0215338365
MESH:D007021 Hypospadias Ethinyl Estradiol 3.7516569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4012013081
MESH:D007248 Infertility, Male decitabine 15.7017581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 15.7017937319
MESH:D007248 Infertility, Male Paraquat 15.704850670
MESH:D007248 Infertility, Male vinclozolin 15.7016467254
MESH:D007249 Inflammation Tamoxifen 4.7719457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.7712200463 12878042
MESH:D007251 Influenza, Human Selenium 10.7716624496
MESH:D007251 Influenza, Human Vitamin E 10.7716624496
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2716580747
MESH:D007674 Kidney Diseases Vitamin E 2.7712488133
MESH:D007676 Kidney Failure, Chronic Selenium 3.8216518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 12.0816705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 12.0816705839
MESH:D007680 Kidney Neoplasms Tamoxifen 12.0818625569
MESH:D007938 Leukemia arsenic trioxide 6.3415070760
MESH:D007938 Leukemia decitabine 6.3419235587 18980019
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.7317077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.2416972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.3814633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 9.3819077051
MESH:D007951 Leukemia, Myeloid decitabine 9.3819117987 17236224 18454857
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 6.1917050201 16467208 20471514 16968895 19850784
MESH:D015470 Leukemia, Myeloid, Acute decitabine 6.1918704418 18206229 18460780 19387464 19010910 17679729
MESH:D015470 Leukemia, Myeloid, Acute trichostatin A 6.1918206229
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.4118055864
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.1716330433 12679006 17107899 16966277 19075265 11161223 15748426 15213294 15336539 17869043 16331271 19225113 12018890 15622746 11468182 17217047 16112521 16891316 17649720 19035177 19642359 12712474 9834237 16823087 17712046
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.2916882451
MESH:D007984 Leydig Cell Tumor vinclozolin 4.6716417039
MESH:D008064 Lipidoses Tamoxifen 3.1117567588 15342952
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 2.7711903743 11408273 17174718 17157831 21278145 16943688 17334410 16221502 16239168
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 4.8812741479 17922224 16015684 17640975 14620537 17631135 16033810 17481882 15893842 16638106 17823541 18412020 12666154 18210741 18263696 12898905 20821823 17714472 14716833 16192424 15996030 15818738 15925388 18472332 10355542 17761835 18054572 16136751 15370692 12445421 15052691 14748882 15057751 17525996 17721639 17557913 16097048 17805973 18279442 12649538 17900296 12546737 13678700 17708605 16116963 17869086 18166357 15673190 11481614 18277467 14724832 12667390 15931870 15338365 14512876 18395914 17944888 18251166 12445418 15730626 12389079 15876570 16011737 18418968 16027843 18156304 15123356 18472094 17976157 12632514 15362042 12958196 17565644 17766677 18429990 18376398 18339082 16248980 14716496 12632512 18395095 18187930 18205269 12609069 18481824 18317297 18420326 18705752 17698563 18006644 12586293 15959796 15650968
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 4.8818564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.8812878042
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 4.8816169303
MESH:D008107 Liver Diseases Carbon Tetrachloride 2.0715720792 16246199 15830285 17285989 16964402
MESH:D017093 Liver Failure Carbon Tetrachloride 4.1015123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.6316899240 14706259
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 17.677678174
MESH:D008113 Liver Neoplasms arsenic trioxide 17.6714682389
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 17.6719294768
MESH:D008113 Liver Neoplasms Clofibric Acid 17.6717602206
MESH:D008113 Liver Neoplasms Tamoxifen 17.6716684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 17.6716984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 13.762876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 13.7620377131
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 13.7612014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 13.7612151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.3015213294
MESH:D008171 Lung Diseases Vitamin E 3.1316863852
MESH:D008175 Lung Neoplasms arsenic trioxide 4.7811798837 19825857
MESH:D008175 Lung Neoplasms Tamoxifen 4.7818625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.7819555203 11884234
MESH:D008175 Lung Neoplasms Vitamin E 4.7811062179
MESH:D008223 Lymphoma decitabine 3.3719470736
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.7019428831
MESH:D008325 Mammary Neoplasms, Experimental Selenium 5.9015318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 5.9011731420 19196722 16827153 19196723 14580682
MESH:D020149 Manganese Poisoning Tamoxifen 4.4919453300
MESH:D008545 Melanoma decitabine 5.1717785578 16505122
MESH:D008545 Melanoma Tamoxifen 5.1719393235 12393984
MESH:D008545 Melanoma trichostatin A 5.1716505122
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.1215990972
MESH:D008654 Mesothelioma Selenium 2.7715107826
MESH:D009101 Multiple Myeloma arsenic trioxide 11.9611468182 19549372 14977855 19417148 15949261
MESH:D009101 Multiple Myeloma decitabine 11.9618172295
MESH:D009101 Multiple Myeloma trichostatin A 11.9618172295
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.6218349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 7.3816882451 16105982
MESH:D009190 Myelodysplastic Syndromes decitabine 7.3819157545 16882708 18608210 19010910
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9612213967
MESH:D009336 Necrosis 2,4-dinitrotoluene 10.1418551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 10.1418551238 7678174
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.9016624393
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.5219393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4919410462
MESH:D009369 Neoplasms decitabine 2.6817925555 19116145 19470736
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.9419189210 19196722 19200415
MESH:D009410 Nerve Degeneration Paraquat 8.4716893418
MESH:D009410 Nerve Degeneration Rotenone 8.4718619942 15790535 17356569
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.1514600291
MESH:D009436 Neural Tube Defects arsenic trioxide 3.0710525206
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 14.8112819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 14.8116049721
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 14.8114694615
MESH:D010051 Ovarian Neoplasms arsenic trioxide 11.2312452020 19769630 16624393
MESH:D010051 Ovarian Neoplasms CD 437 11.2317474084
MESH:D010051 Ovarian Neoplasms decitabine 11.2319331143 19259094
MESH:D010051 Ovarian Neoplasms trichostatin A 11.2319331143
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 8.6315580305
MESH:D010190 Pancreatic Neoplasms decitabine 8.6319294695
MESH:D010190 Pancreatic Neoplasms trichostatin A 8.6319294695
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6211578682
MESH:D010235 Paraganglioma arsenic trioxide 4.1019927285
MESH:D010300 Parkinson Disease Paraquat 5.5015451049 12911755 15824117 11181820 16140633 16510128 11445065 11124998
MESH:D010300 Parkinson Disease Rotenone 5.5019114014 16412576 18191903 11535288 16140633 11445065 15451049 18619942 19232380
MESH:D010302 Parkinson Disease, Secondary Paraquat 4.3716190885
MESH:D020734 Parkinsonian Disorders Rotenone 4.0215927086 18197244 15795934 15574749
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1912520081
MESH:D010954 Plasmacytoma Selenium 4.8315087411
MESH:D011014 Pneumonia Paraquat 4.3912504350
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4918163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.2811896295 11399792 11222880 11118676
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 9.2819015723 18042343 18220299
MESH:D055728 Primary Myelofibrosis decitabine 12.2117616702
MESH:D055728 Primary Myelofibrosis trichostatin A 12.2117616702
MESH:D011469 Prostatic Diseases vinclozolin 4.8718220299
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.7215572423
MESH:D011471 Prostatic Neoplasms arsenic trioxide 1.8819131511
MESH:D011471 Prostatic Neoplasms Calcitriol 1.8818247401 16289102 15754350 12479363 16644109
MESH:D011471 Prostatic Neoplasms Tamoxifen 1.8815067354
MESH:D011471 Prostatic Neoplasms trichostatin A 1.8819789329 18798265
MESH:D011471 Prostatic Neoplasms Vitamin E 1.8815084515
MESH:D011472 Prostatitis vinclozolin 4.8718629315
MESH:D011537 Pruritus Ethinyl Estradiol 3.2516919318 15861022
MESH:D011658 Pulmonary Fibrosis Paraquat 2.8917997886 16324872
MESH:D012128 Respiratory Distress Syndrome, Adult Paraquat 3.8411700416
MESH:D012135 Respiratory Sounds Paraquat 3.9911874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7718990726
MESH:D012162 Retinal Degeneration Paraquat 3.8216458197
MESH:D012208 Rhabdomyosarcoma decitabine 4.3419155313
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.9016646077
MESH:D012640 Seizures 2,4-dinitrotoluene 5.7118551238
MESH:D012640 Seizures 2,6-dinitrotoluene 5.7118551238
MESH:D012871 Skin Diseases Vitamin E 2.4218709164
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.0116192470
MESH:D013088 Spermatocele Ethinyl Estradiol 11.3716709447
MESH:D013088 Spermatocele Tamoxifen 11.3716709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.9819457130
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.5517007042
MESH:D013274 Stomach Neoplasms decitabine 2.5519037991
MESH:D020521 Stroke Vitamin E 3.4716517955
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5611994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0915669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8512697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 7.1519014326
MESH:D013964 Thyroid Neoplasms decitabine 7.1517967635
MESH:D016171 Torsades de Pointes arsenic trioxide 3.9015213294
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 19.5716049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 19.5716049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 19.5720435036 11780464 12845720 12973940
MESH:D001749 Urinary Bladder Neoplasms CD 437 19.5716720286
MESH:D001749 Urinary Bladder Neoplasms decitabine 19.5717616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 19.5717572228 8653321 16712894
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 11.7810091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 11.7810091137
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.2314692618
MESH:D014604 Uveal Neoplasms decitabine 4.8617785578
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5412125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4814671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1915886252
Pathway ID Pathway Name
REACT:21257 Metabolism of RNA
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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