AutismKB 2.0

Annotation Detail for SFRP1


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Basic Information Top
Gene Symbol:SFRP1 ( FRP,FRP-1,FRP1,FrzA,SARP2 )
Gene Full Name: secreted frizzled-related protein 1
Band: 8p11.21
Quick LinksEntrez ID:6422; OMIM: 604156; Uniprot ID:SFRP1_HUMAN; ENSEMBL ID: ENSG00000104332; HGNC ID: 10776
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04310Wnt signaling pathway
No data
Pathway IDPathway Name
200171Validated targets of C-MYC transcriptional repression
Pathway IDPathway Name
P00005Angiogenesis
P00057Wnt signaling pathway
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1934Cancer
2003Metaplastic polyp
2060Glaucoma
2164Barrett's esophagus
2178Retinal disease
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of SFRP1 mRNAaffects expression 16483693
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SFRP1 mRNAaffects cotreatment|increases expression 18164116
D001645 Biguanides Biguanides analog affects the expression of SFRP1 mRNAaffects expression 17463086
D002794 Choline Choline affects the expression of SFRP1 mRNAaffects expression 17616785
C014347 decitabine decitabine affects the expression of SFRP1 mRNAaffects expression 18538736
C014347 decitabine decitabine affects the methylation of SFRP1 promoteraffects methylation 17882284
C014347 decitabine [decitabine affects the methylation of SFRP1 promoter] which affects the expression of SFRP1 mRNAaffects expression|affects methylation 18283316
C014347 decitabine [decitabine co-treated with trichostatin A] results in increased expression of SFRP1 mRNAaffects cotreatment|increases expression 17923031
C014347 decitabine decitabine results in decreased methylation of SFRP1 promoterdecreases methylation 19387464
C014347 decitabine decitabine results in increased expression of SFRP1 mRNAincreases expression 19234609
19387464
D003907 Dexamethasone Dexamethasone results in increased expression of SFRP1 mRNAincreases expression 16144937
D003907 Dexamethasone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of SFRP1 mRNAaffects cotreatment|decreases expression 16054899
D004040 Dietary Carbohydrates Dietary Carbohydrates results in decreased expression of SFRP1 mRNAdecreases expression 17490981
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SFRP1 mRNAaffects cotreatment|increases expression 18164116
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of SFRP1 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of SFRP1 mRNAdecreases expression 16174780
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of SFRP1 mRNAdecreases expression 16174780
D015056 1-Methyl-3-isobutylxanthine [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of SFRP1 mRNAaffects cotreatment|decreases expression 16054899
D015735 Mifepristone Mifepristone results in increased expression of SFRP1 mRNAincreases expression 17584828
D011073 Polyamines Polyamines analog affects the expression of SFRP1 mRNAaffects expression 17463086
D011073 Polyamines Polyamines analog affects the methylation of SFRP1 promoteraffects methylation 19934284
D011073 Polyamines Polyamines analog results in increased expression of SFRP1 mRNAincreases expression 19934284
D011794 Quercetin Quercetin results in decreased expression of SFRP1 mRNAdecreases expression 15309432
C059514 resveratrol resveratrol results in decreased expression of SFRP1 mRNAdecreases expression 12569576
C089730 rosiglitazone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of SFRP1 mRNAaffects cotreatment|decreases expression 16054899
D013629 Tamoxifen Tamoxifen affects the expression of SFRP1 mRNAaffects expression 17555576
D019772 Topotecan SFRP1 protein affects the susceptibility to Topotecanaffects response to substance 16217747
C012589 trichostatin A [decitabine co-treated with trichostatin A] results in increased expression of SFRP1 mRNAaffects cotreatment|increases expression 17923031
D002762 Cholecalciferol Cholecalciferol results in increased expression of SFRP1 mRNAincreases expression 17170073
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.4914745880
MESH:D000138 Acidosis Ammonium Chloride 3.5018287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8917505938
MESH:D058186 Acute Kidney Injury resveratrol 3.7916538975
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8014692618
MESH:D000236 Adenoma beta-Naphthoflavone 11.0819389873
MESH:D000236 Adenoma Diethylnitrosamine 11.0810737359 6695378
MESH:D000236 Adenoma resveratrol 11.0815688382
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 3.8417162532 17620307 18056438 19061943 16434500 19052882
MESH:D000544 Alzheimer Disease resveratrol 4.4916162502 16183991
MESH:D000544 Alzheimer Disease rosiglitazone 4.4919621015
MESH:D000743 Anemia, Hemolytic Quercetin 4.1817084956
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.4011256880
MESH:D001169 Arthritis, Experimental Dexamethasone 12.1017659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 12.1015885639
MESH:D001169 Arthritis, Experimental resveratrol 12.1017115116
MESH:D001260 Ataxia Telangiectasia Quercetin 4.9215336622
MESH:D050197 Atherosclerosis resveratrol 3.2316873680 17967414
MESH:D001321 Autistic Disorder Choline 3.3516818868
MESH:D001327 Autoimmune Diseases Cholecalciferol 10.8516142846
MESH:D001327 Autoimmune Diseases Quercetin 10.8519761891
MESH:D002545 Brain Ischemia resveratrol 4.2217600658
MESH:D001943 Breast Neoplasms marker/mechanism 18283316
MESH:D001943 Breast Neoplasms decitabine 2.3418320071 19208741
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.3417474063
MESH:D001943 Breast Neoplasms Quercetin 2.3418628248
MESH:D001943 Breast Neoplasms resveratrol 2.3417534123 16393696 17651959
MESH:D001943 Breast Neoplasms Tamoxifen 2.3417440819 19084267 19487384 11161223 21138602 19155303 16873071 19244106 19289846 20005174 18425577 15565566 20859285 16202921 15668708 20135344 17049068 19103187 20390343 16818667 17261762 19142967 19288272 18984771 19410462 19189210 19200415 16273361 21152245 20065188 19011961 18815881 17893378 19189212 19066611 18855134 18997820 19059307 18351453 19221464 18629630 18821012 17242785 20544844 19115204
MESH:D002105 Cadmium Poisoning Quercetin 5.4916962696
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.4419066611
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 6.5420101231 18210153 19519916 16681979 20512989 16935385 18393292 19208518 20084675 18691550 18978308 16878318 3581430 20432363 19335982 18665156 19394651 18788625 18785209 20727157 19171122 10672840 21159647 16569478 20007298 19418558 17761372 20514400 16540662 19919837 16830150 10737359 16288022 16328049 17428255 16502159 17162532 17055752 19822196 19052882 19539802 20214788 20935162 18056438 16807293 18971187 19107877 3084413 19383236 19701751 16698587 18506893 16779866 17978847 20524982 18494052 17138121 11831363 17173139
MESH:D006528 Carcinoma, Hepatocellular Quercetin 6.5419519916 12508355
MESH:D006528 Carcinoma, Hepatocellular resveratrol 6.5419321006 16227395
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 6.5416924424
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.5316675471
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.8917234771
MESH:D002294 Carcinoma, Squamous Cell decitabine 4.8619215824
MESH:D002294 Carcinoma, Squamous Cell resveratrol 4.8616227395
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.5517572228
MESH:D006332 Cardiomegaly Quercetin 3.2819794523
MESH:D002318 Cardiovascular Diseases resveratrol 3.4315458977
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 2.8117174075 2727394 21159647 7505956
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.6319052882
MESH:D002779 Cholestasis Ethinyl Estradiol 2.8217333356 17681005 16919318 17110522 15861022 11677210 16105132
MESH:D003092 Colitis resveratrol 4.0616474422
MESH:D003110 Colonic Neoplasms decitabine 8.2717616700
MESH:D003110 Colonic Neoplasms Dexamethasone 8.2715824018
MESH:D003110 Colonic Neoplasms Quercetin 8.2716640504 17191121 19440933 11134977 17148506 19056647 15741050
MESH:D003110 Colonic Neoplasms resveratrol 8.2716338953
MESH:D015179 Colorectal Neoplasms marker/mechanism 18716850 17923031
MESH:D015179 Colorectal Neoplasms decitabine 4.8918981723
MESH:D015179 Colorectal Neoplasms Polyamines 4.8919934284
MESH:D015179 Colorectal Neoplasms Quercetin 4.8918852136 18095365
MESH:D015179 Colorectal Neoplasms resveratrol 4.8916550006
MESH:D003327 Coronary Disease resveratrol 3.7116507316
MESH:D019465 Craniofacial Abnormalities Dexamethasone 2.2817728286
MESH:D003711 Demyelinating Diseases Tamoxifen 4.3019031437
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 3.3412438553
MESH:D002658 Developmental Disabilities Choline 4.6316818868
MESH:D003920 Diabetes Mellitus rosiglitazone 4.2417446233
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 8.3719496084
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 8.3716873680
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.6320387270
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 4.6312642470
MESH:D003928 Diabetic Nephropathies resveratrol 8.8516286809
MESH:D003928 Diabetic Nephropathies Tamoxifen 8.8519279558
MESH:D003967 Diarrhea Dexamethasone 3.637237001
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 2.0419107877
MESH:D004485 Eczema Dexamethasone 4.4012438553
MESH:D004487 Edema Dexamethasone 11.3719703484
MESH:D004487 Edema resveratrol 11.378985016
MESH:D004487 Edema rosiglitazone 11.3712083418
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 14.9912538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 14.9917872969
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 14.9919031437
MESH:D004701 Endocrine Gland Neoplasms decitabine 13.8419294695
MESH:D004701 Endocrine Gland Neoplasms trichostatin A 13.8419294695
MESH:D016889 Endometrial Neoplasms Tamoxifen 3.0020544844 19155303 17893378 16202921
MESH:D004715 Endometriosis Mifepristone 4.3116134523
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.7817923197
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.0616302075
MESH:D005234 Fatty Liver Diethylnitrosamine 18.3020387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 18.3015345470
MESH:D005234 Fatty Liver rosiglitazone 18.3019196556
MESH:D005234 Fatty Liver Tamoxifen 18.3014986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.1916709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.4714745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.1219069698
MESH:D005355 Fibrosis Quercetin 3.8419474275
MESH:D005909 Glioblastoma Quercetin 7.4219804834
MESH:D005909 Glioblastoma trichostatin A 7.4218801729
MESH:D005910 Glioma Quercetin 3.0317643826
MESH:D006258 Head and Neck Neoplasms decitabine 3.4419215824
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 3.057520565
MESH:D006561 Herpes Simplex resveratrol 4.1216876885
MESH:D006930 Hyperalgesia rosiglitazone 3.8612083418
MESH:D006937 Hypercholesterolemia resveratrol 3.9417188708
MESH:D006943 Hyperglycemia Quercetin 3.9718262572 11834736
MESH:D006949 Hyperlipidemias resveratrol 3.9616873680
MESH:D006973 Hypertension Dexamethasone 5.5217042910
MESH:D006973 Hypertension Quercetin 5.5218356687
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.2417488730
MESH:D007021 Hypospadias Ethinyl Estradiol 3.7516945680 16569931
MESH:D007077 Ileal Diseases 1-Methyl-3-isobutylxanthine 5.3918306037
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.5817600658
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4012013081
MESH:D007248 Infertility, Male decitabine 6.5717581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.5717937319
MESH:D007249 Inflammation Dexamethasone 15.538960868 11099482
MESH:D007249 Inflammation Diethylnitrosamine 15.5318785209
MESH:D007249 Inflammation resveratrol 15.5316366677
MESH:D007249 Inflammation rosiglitazone 15.5312083418
MESH:D007249 Inflammation Tamoxifen 15.5319457130
MESH:D015212 Inflammatory Bowel Diseases marker/mechanism 18716850
MESH:D007251 Influenza, Human Quercetin 11.0116624496
MESH:D007251 Influenza, Human resveratrol 11.0116624496
MESH:D007333 Insulin Resistance rosiglitazone 3.7616306350
MESH:D007579 Jejunal Diseases 1-Methyl-3-isobutylxanthine 5.3918306037
MESH:D007627 Keloid Quercetin 4.8917086741
MESH:D007674 Kidney Diseases Quercetin 3.0616962696
MESH:D007680 Kidney Neoplasms Tamoxifen 2.9918625569
MESH:D007889 Leiomyoma marker/mechanism 15972578
MESH:D007938 Leukemia decitabine 6.4618980019 19235587
MESH:D007938 Leukemia Quercetin 6.4617468513
MESH:D007951 Leukemia, Myeloid decitabine 3.9417236224 19117987 18454857
MESH:D015470 Leukemia, Myeloid, Acute decitabine 4.2318460780 19387464 19010910 18704418 17679729 18206229
MESH:D015470 Leukemia, Myeloid, Acute trichostatin A 4.2318206229
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.4118055864
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 3.5316087638
MESH:D008064 Lipidoses Tamoxifen 3.1117567588 15342952
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.7918522880 19638242 18665156 18407596 20032147
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 4.9816718785
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 4.9812741479
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 4.9815980055 17347453
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 4.9818564211
MESH:D008107 Liver Diseases Diethylnitrosamine 2.0817034775
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 14.0119389873 21295105
MESH:D008113 Liver Neoplasms Diethylnitrosamine 14.0119638242 19090486 12112319 20501860 12771043 18648771 21047994 18644402 20405173 20101389 20452335 18977376 19499222 18978307 20492335 19294768 10737359 20118626 21071580 15175105 19812893 19551842 2862719 18754104 21278145 2422723 16942905 19254457 19427195 21167192 19850985 19996281 19690152 9163691 19255062 20583210 19833225 19642983 19073162 19426721 20434301 19256749 15885732 20137499
MESH:D008113 Liver Neoplasms Quercetin 14.0118980244
MESH:D008113 Liver Neoplasms resveratrol 14.0119073162 19812893 19321006 20405173
MESH:D008113 Liver Neoplasms Tamoxifen 14.0116684651
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 9.7518164116
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 9.7516842330 16267830 17942915 19004024 9362446 18775883 3124819 19009564 18164116 17174075 18544905 19539802 18253720 2563599 18308698 19519916 19126423 21159647 18282651 17854601 18079962 18093689
MESH:D008114 Liver Neoplasms, Experimental Quercetin 9.7519519916
MESH:D008175 Lung Neoplasms Dexamethasone 4.8415824018 11195469
MESH:D008175 Lung Neoplasms Diethylnitrosamine 4.8421163286 20970405 6695378 20512841
MESH:D008175 Lung Neoplasms Quercetin 4.8416280456
MESH:D008175 Lung Neoplasms Tamoxifen 4.8418625569
MESH:D008223 Lymphoma decitabine 3.3719470736
MESH:D016393 Lymphoma, B-Cell resveratrol 4.2417088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.8114749477
MESH:D015674 Mammary Neoplasms, Animal resveratrol 9.8015688416
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 9.8019428831
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 9.8711606380 8985016
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 9.8716827153
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 9.8719196723 14580682 16827153 11731420 19196722
MESH:D020149 Manganese Poisoning Tamoxifen 4.4919453300
MESH:D008545 Melanoma decitabine 7.2717785578 16505122
MESH:D008545 Melanoma resveratrol 7.2717992120
MESH:D008545 Melanoma Tamoxifen 7.2719393235 12393984
MESH:D008545 Melanoma trichostatin A 7.2716505122
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.1215990972
MESH:D008659 Metabolic Diseases resveratrol 4.3117112576
MESH:D024821 Metabolic Syndrome X rosiglitazone 4.3217261469
MESH:D009101 Multiple Myeloma decitabine 16.9518172295
MESH:D009101 Multiple Myeloma Dexamethasone 16.9515867202 15744524 16118317
MESH:D009101 Multiple Myeloma resveratrol 16.9517935668 17164350 16490592 17049120 14749477 16267019
MESH:D009101 Multiple Myeloma trichostatin A 16.9518172295
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.8117962980
MESH:D009190 Myelodysplastic Syndromes decitabine 7.5219157545 18608210 16882708 19010910
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 7.529809623
MESH:D009203 Myocardial Infarction Quercetin 5.9619595682
MESH:D009203 Myocardial Infarction resveratrol 5.9616317513 17125593 16525036 17015251 17188708 16456233
MESH:D017202 Myocardial Ischemia resveratrol 3.9517125593 17015251
MESH:D015428 Myocardial Reperfusion Injury Quercetin 3.7419207477
MESH:D009205 Myocarditis resveratrol 4.7017322642
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.643581430 9029167
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.6419393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4919410462
MESH:D009369 Neoplasms decitabine 5.2219470736 19116145 17925555
MESH:D009369 Neoplasms Quercetin 5.2215185748
MESH:D009374 Neoplasms, Experimental resveratrol 3.948985016
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.9419189210 19196722 19200415
MESH:D009447 Neuroblastoma Topotecan 3.8115176712
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 8.3420387270
MESH:D019636 Neurodegenerative Diseases resveratrol 8.3417652729
MESH:D020078 Neurogenic Inflammation Quercetin 10.4817929310
MESH:D020078 Neurogenic Inflammation resveratrol 10.4817929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.0620387270
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 9.9919495926
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 9.9917513867
MESH:D010051 Ovarian Neoplasms decitabine 11.2319331143 19259094
MESH:D010051 Ovarian Neoplasms Mifepristone 11.2316525653
MESH:D010051 Ovarian Neoplasms Quercetin 11.2319005980
MESH:D010051 Ovarian Neoplasms trichostatin A 11.2319331143
MESH:D010190 Pancreatic Neoplasms decitabine 12.2119294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 12.2116540662
MESH:D010190 Pancreatic Neoplasms Quercetin 12.2116965848
MESH:D010190 Pancreatic Neoplasms trichostatin A 12.2119294695
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6211578682
MESH:D011230 Precancerous Conditions Diethylnitrosamine 9.032563599
MESH:D011230 Precancerous Conditions Quercetin 9.0319056647
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma marker/mechanism 17148581
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.5121297632
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 4.1216679765
MESH:D055728 Primary Myelofibrosis decitabine 12.2117616702
MESH:D055728 Primary Myelofibrosis trichostatin A 12.2117616702
MESH:D011471 Prostatic Neoplasms Cholecalciferol 1.9117024972
MESH:D011471 Prostatic Neoplasms Quercetin 1.9114715546 17292933
MESH:D011471 Prostatic Neoplasms resveratrol 1.9117675339 17718901 17804756 16731767 17636462 15767336
MESH:D011471 Prostatic Neoplasms Tamoxifen 1.9115067354
MESH:D011471 Prostatic Neoplasms trichostatin A 1.9119789329 18798265
MESH:D011537 Pruritus Ethinyl Estradiol 3.2515861022 16919318
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.5316325855
MESH:D015427 Reperfusion Injury resveratrol 3.2417058453 17520802 16317513 16314181 15827377
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 3.9511700416 18379247
MESH:D012208 Rhabdomyosarcoma decitabine 4.3419155313
MESH:D012554 Schistosomiasis japonica Quercetin 5.4916862918
MESH:D012878 Skin Neoplasms resveratrol 3.008985016 15837718
MESH:D013088 Spermatocele Ethinyl Estradiol 11.3716709447
MESH:D013088 Spermatocele Tamoxifen 11.3716709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.9819457130
MESH:D013272 Stomach Diseases Dexamethasone 4.2615472012
MESH:D013274 Stomach Neoplasms decitabine 2.5119037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.5118456281
MESH:D013276 Stomach Ulcer Dexamethasone 3.4315138204
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.4216321402
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5611994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0915669648
MESH:D013964 Thyroid Neoplasms decitabine 7.1117967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 7.117505956
MESH:D014062 Tongue Neoplasms resveratrol 4.1516227395
MESH:D001749 Urinary Bladder Neoplasms decitabine 8.2717616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Quercetin 8.2716720314
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 8.2717572228 16712894 8653321
MESH:D002583 Uterine Cervical Neoplasms resveratrol 4.0417473185
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 9.2914692618
MESH:D014594 Uterine Neoplasms resveratrol 9.2917044934
MESH:D014604 Uveal Neoplasms decitabine 4.8617785578
MESH:D014605 Uveitis Dexamethasone 4.761336536
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4814671159 15869587
MESH:D018487 Ventricular Dysfunction, Left resveratrol 4.2417488730
Pathway ID Pathway Name
KEGG:04310 Wnt signaling pathway
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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