AutismKB 2.0

Annotation Detail for FBRS


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Basic Information Top
Gene Symbol:FBRS ( FBS,FBS1,FLJ11618 )
Gene Full Name: fibrosin
Band: 16p11.2
Quick LinksEntrez ID:64319; OMIM: 608601; Uniprot ID:FBSH_HUMAN; ENSEMBL ID: ENSG00000156860; HGNC ID: 20442
Relate to Another Database: SFARIGene; denovo-db
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of FBRS mRNAaffects expression 17562736
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 5.2610982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8610977129
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6916177239 12392966 11287661 11529661 19739265 12958197 16081117 16393943 12705907 19164858 17906064 19420014 16109766 12540782 11834606 14550746 18071297 12153990 17522070 11743745 11421492 12594235 10915739 10774834 15968718 19370779 19085960 2444490 14986274 16485898 16227642 19923254 16781746 10663392 11461765 17562736 18713872 15619225 11739529 14725611 19416960
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.5119426721
MESH:D005756 Gastritis Acetaminophen 5.0916983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1516870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4715629191 12587719
MESH:D008107 Liver Diseases Acetaminophen 1.7219784758 16611625 12969438 12587719 19014921 11587558 16610002 19460945
MESH:D017114 Liver Failure, Acute Acetaminophen 3.8116871587 17185352
MESH:D008546 Melanoma, Experimental Acetaminophen 4.4719513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3618514411
MESH:D010146 Pain Acetaminophen 2.8716870215
MESH:D014581 Urticaria Acetaminophen 3.6710982225
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018