Annotation Detail for MMP25
Basic Information
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| Gene Symbol: | MMP25 ( MMP-25,MMP20,MMP20A,MMPL1,MT-MMP 6,MT-MMP6,MT6-MMP,MT6MMP,MTMMP6 ) |
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| Gene Full Name: | matrix metallopeptidase 25 |
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| Band: | 16p13.3 |
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| Quick Links | Entrez ID:64386; OMIM: 608482; Uniprot ID:MMP25_HUMAN; ENSEMBL ID: ENSG00000008516; HGNC ID: 14246 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| P00004 | Alzheimer disease-presenilin pathway |
| Desease ID | Desease Name |
|---|
| 2053 | Colon cancer |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D006830 |
Hydralazine |
[Hydralazine co-treated with Valproic Acid] results in increased expression of MMP25 mRNA | affects cotreatment|increases expression | 17183730
|
| D014635 |
Valproic Acid |
[Hydralazine co-treated with Valproic Acid] results in increased expression of MMP25 mRNA | affects cotreatment|increases expression | 17183730
|
| C034028 |
vanadyl sulfate |
vanadyl sulfate results in increased expression of MMP25 mRNA | increases expression | 16330358
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
Valproic Acid |
4.23 | 8875741 |
| MESH:D000015 |
Abnormalities, Multiple |
|
Valproic Acid |
4.41 | 19490988 |
| MESH:D000550 |
Amblyopia |
|
Valproic Acid |
6.10 | 17688650 |
| MESH:D001008 |
Anxiety Disorders |
|
Valproic Acid |
3.94 | 17497229 |
| MESH:D001321 |
Autistic Disorder |
|
Valproic Acid |
1.98 | 18177632 15238991 19460635 18316065 16609825 18558336 18775368 20603192 18940202 17507914 17688650 18985861 19232924 18396377 17157402 |
| MESH:D001714 |
Bipolar Disorder |
|
Valproic Acid |
3.26 | 20046352 17594078 |
| MESH:D001848 |
Bone Diseases, Developmental |
|
Valproic Acid |
3.66 | 8888407 |
| MESH:D002659 |
Child Development Disorders, Pervasive |
|
Valproic Acid |
2.83 | 20734317 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Valproic Acid |
1.91 | 8888407 17688650 16575769 |
| MESH:D003921 |
Diabetes Mellitus, Experimental |
|
vanadyl sulfate |
4.76 | 16684804 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Valproic Acid |
2.26 | 19641884 1733752 |
| MESH:D004421 |
Dystonia |
|
Valproic Acid |
4.58 | 1851702 |
| MESH:D004831 |
Epilepsies, Myoclonic |
|
Valproic Acid |
4.81 | 17275665 3659116 |
| MESH:D004828 |
Epilepsies, Partial |
|
Valproic Acid |
4.78 | 16628512 3922381 |
| MESH:D004827 |
Epilepsy |
|
Valproic Acid |
3.12 | 18234410 20417680 |
| MESH:D004832 |
Epilepsy, Absence |
|
Valproic Acid |
4.00 | 7562514 6254150 6426943 |
| MESH:D017029 |
Epilepsy, Complex Partial |
|
Valproic Acid |
4.95 | 7750514 |
| MESH:D004830 |
Epilepsy, Tonic-Clonic |
|
Valproic Acid |
4.81 | 3659116 |
| MESH:D005234 |
Fatty Liver |
|
Valproic Acid |
3.78 | 19224547 14986274 |
| MESH:D005315 |
Fetal Diseases |
|
Valproic Acid |
5.75 | 16575769 |
| MESH:D005317 |
Fetal Growth Retardation |
|
Valproic Acid |
4.71 | 8888407 18558336 |
| MESH:D006849 |
Hydrocephalus |
|
Valproic Acid |
5.61 | 17688650 |
| MESH:D046110 |
Hypertension, Pregnancy-Induced |
|
Hydralazine |
5.28 | 16612254 |
| MESH:D015470 |
Leukemia, Myeloid, Acute |
|
Valproic Acid |
2.20 | 16294345 17596541 |
| MESH:D017563 |
Lung Diseases, Interstitial |
|
Valproic Acid |
5.13 | 17228818 |
| MESH:D008881 |
Migraine Disorders |
|
Valproic Acid |
3.50 | 18765137 18803445 |
| MESH:D009139 |
Musculoskeletal Abnormalities |
|
Valproic Acid |
4.51 | 8888407 |
| MESH:D009190 |
Myelodysplastic Syndromes |
|
Valproic Acid |
3.37 | 17596541 |
| MESH:D009436 |
Neural Tube Defects |
|
Valproic Acid |
3.39 | 8888407 16359493 |
| MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
Valproic Acid |
4.57 | 20603192 |
| MESH:D019310 |
Pseudolymphoma |
|
Valproic Acid |
5.41 | 12752131 11422049 |
| MESH:D012208 |
Rhabdomyosarcoma |
|
Valproic Acid |
4.70 | 19155313 |
| MESH:D012559 |
Schizophrenia |
|
Valproic Acid |
2.11 | 15737665 19110320 |
| MESH:D012640 |
Seizures |
|
Valproic Acid |
3.02 | 11044598 15475178 3137016 11738929 16876388 17978042 14763951 1511512 |
| MESH:D016135 |
Spinal Dysraphism |
|
Valproic Acid |
4.13 | 19490988 |
| MESH:D013226 |
Status Epilepticus |
|
Valproic Acid |
5.41 | 12833885 |
| MESH:D014178 |
Translocation, Genetic |
|
Valproic Acid |
6.10 | 17262798 |
| MESH:D020194 |
Unverricht-Lundborg Syndrome |
|
Valproic Acid |
5.26 | 3119515 |
| MESH:D014564 |
Urogenital Abnormalities |
|
Valproic Acid |
5.30 | 8888407 |
| Drugbank ID |
Action |
Drug Name |
Description |
|---|
| DB00786 |
antagonist |
Marimastat |
Antineoplastic Agents;Enzyme Inhibitors |
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