AutismKB 2.0

Annotation Detail for SFTPD


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SFTPD ( COLEC7,PSP-D,SFTP4,SP-D )
Gene Full Name: surfactant protein D
Band: 10q22.3
Quick LinksEntrez ID:6441; OMIM: 178635; Uniprot ID:SFTPD_HUMAN; ENSEMBL ID: ENSG00000133661; HGNC ID: 10803
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04145Phagosome
No data
Pathway IDPathway Name
200191Regulation of retinoblastoma protein
200194FOXA1 transcription factor network
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1761Respiratory tract disease
1781Rheumatoid arthritis
1803Periodontitis
1804Chronic obstructive airway disease
1813Silicosis
1826Cystic fibrosis
1962Respiratory distress syndrome
2014Pulmonary alveolar proteinosis
2052Infection
2111Systemic infection
2192Lung disease
Desease Name
respiratory syncytial virus infection
NORMALVARIATION
Concentration of Surfactant Protein D
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of SFTPD mRNAaffects expression 16483693
C020711 beryllium sulfate beryllium sulfate results in increased expression of SFTPD mRNAincreases expression 16314022
D001761 Bleomycin Bleomycin results in increased expression of SFTPD mRNAincreases expression 11880309
D001761 Bleomycin Bleomycin results in increased expression of SFTPD proteinincreases expression 11880309
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of SFTPD mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SFTPD mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of SFTPD mRNAincreases expression 17557909
D015025 Zearalenone Zearalenone results in increased expression of SFTPD mRNAincreases expression 17557909
D006851 Hydrochloric Acid Hydrochloric Acid results in decreased expression of SFTPD proteindecreases expression 18573544
D006851 Hydrochloric Acid Hydrochloric Acid results in increased expression of SFTPD proteinincreases expression 11880309
D006851 Hydrochloric Acid S-methylisothiopseudouronium inhibits the reaction [Hydrochloric Acid results in decreased expression of SFTPD protein]decreases expression|decreases reaction 18573544
C007350 nitrofen nitrofen results in decreased expression of SFTPD mRNAdecreases expression 11057544
D010100 Oxygen [Paraquat co-treated with Oxygen] results in increased expression of SFTPD proteinaffects cotreatment|increases expression 11880309
D010269 Paraquat Paraquat results in decreased expression of SFTPD proteindecreases expression 17503247
D010269 Paraquat Paraquat results in decreased expression of SFTPD mRNAdecreases expression 17215068
D010269 Paraquat [Paraquat co-treated with Oxygen] results in increased expression of SFTPD proteinaffects cotreatment|increases expression 11880309
D010269 Paraquat Paraquat results in decreased expression of SFTPD proteindecreases expression 17616020
D010269 Paraquat Paraquat results in increased expression of SFTPD proteinincreases expression 17616020
C027744 S-methylisothiopseudouronium S-methylisothiopseudouronium inhibits the reaction [Hydrochloric Acid results in decreased expression of SFTPD protein]decreases expression|decreases reaction 18573544
C027744 S-methylisothiopseudouronium S-methylisothiopseudouronium inhibits the reaction [Sucralfate results in decreased expression of SFTPD protein]decreases expression|decreases reaction 18573544
D013392 Sucralfate S-methylisothiopseudouronium inhibits the reaction [Sucralfate results in decreased expression of SFTPD protein]decreases expression|decreases reaction 18573544
D013392 Sucralfate Sucralfate results in decreased expression of SFTPD proteindecreases expression 18573544
D013726 Terbutaline [Terbutaline co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SFTPD proteinaffects cotreatment|increases expression 9476903
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SFTPD mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of SFTPD mRNAdecreases expression 18990726
D013755 Tetradecanoylphorbol Acetate [Terbutaline co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SFTPD proteinaffects cotreatment|increases expression 9476903
D014051 Toluene 2,4-Diisocyanate Toluene 2,4-Diisocyanate results in increased expression of SFTPD mRNAincreases expression 11379042
D014212 Tretinoin Tretinoin results in increased expression of SFTPD mRNAincreases expression 16965567
C025643 vinclozolin vinclozolin affects the expression of SFTPD mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Terbutaline 8.8114610225
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.8114514962 15322242 11752688
MESH:D000138 Acidosis Ammonium Chloride 10.7018287403
MESH:D000138 Acidosis Hydrochloric Acid 10.7015920416 19262391 16144966 20872349 11574821 12771618
MESH:D000141 Acidosis, Renal Tubular Hydrochloric Acid 5.7617183249
MESH:D000142 Acidosis, Respiratory Hydrochloric Acid 5.8120597076
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.9417505938
MESH:D055371 Acute Lung Injury Bleomycin 15.6017118201
MESH:D055371 Acute Lung Injury Hydrochloric Acid 15.6019060228 15970105 16759491 11953099 19094174 19760209 11850527
MESH:D055371 Acute Lung Injury Oxygen 15.6016759491
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8114692618
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.3716835633
MESH:D000382 Agricultural Workers' Diseases Paraquat 3.7611874814
MESH:D000505 Alopecia Tretinoin 3.6015955085
MESH:D000686 Amyloidosis Terbutaline 5.617986221
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9311748828
MESH:D000860 Anoxia Bleomycin 18.8615782499
MESH:D000860 Anoxia Hydrochloric Acid 18.8615090967
MESH:D000860 Anoxia Oxygen 18.8620872349
MESH:D001008 Anxiety Disorders vinclozolin 3.6219015723
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.4511256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.1615885639
MESH:D001169 Arthritis, Experimental Tretinoin 7.1616412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2616292516
MESH:D001249 Asthma Toluene 2,4-Diisocyanate 5.2510797510 16210060 12684321 11742282 19187332 17015710 7684630 11467998 18394133 15855793 15590891 12585506 12762349 11077013 170078 10934080 16792590 6091945 3040596 20032816 15590890 6091946 8156442
MESH:D001249 Asthma Tretinoin 5.2516456186
MESH:D050197 Atherosclerosis Oxygen 3.7916391483
MESH:D001321 Autistic Disorder Terbutaline 3.4317400887 16417856
MESH:D001471 Barrett Esophagus Tretinoin 4.3916935849
MESH:D001778 Blood Coagulation Disorders Hydrochloric Acid 15.3915920416
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 15.3912125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 15.3916206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7515746008
MESH:D001943 Breast Neoplasms Oxygen 2.0417263869
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.0420435547
MESH:D001943 Breast Neoplasms Toluene 2,4-Diisocyanate 2.0411921183
MESH:D001943 Breast Neoplasms Tretinoin 2.0416166294 16873071 16443354
MESH:D016535 Bronchial Hyperreactivity Hydrochloric Acid 9.2012378975
MESH:D016535 Bronchial Hyperreactivity Toluene 2,4-Diisocyanate 9.208156442 12507178 15590891
MESH:D001986 Bronchial Spasm Hydrochloric Acid 5.4715578804
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.5816813970
MESH:D019559 Capillary Leak Syndrome Terbutaline 5.8611713377 9428835
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7816835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.1616168501
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 1.891917145
MESH:D002294 Carcinoma, Squamous Cell Bleomycin 7.766189445
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 7.7618922899
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 7.7616051514 16096774
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3518850075 18670907 16120746
MESH:D002386 Cataract Tretinoin 3.0817460283
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.5816129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1416835633
MESH:D002779 Cholestasis Ethinyl Estradiol 2.8611677210 17681005 16919318 16105132 17333356 15861022 17110522
MESH:D002822 Choriocarcinoma Tretinoin 5.1616461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.7415668235 16354765 12621046 8697196 15340226
MESH:D002972 Cleft Palate Tretinoin 5.749407595
MESH:D003092 Colitis Tretinoin 3.6917035595
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0417141729 14669216
MESH:D003371 Cough Terbutaline 5.5619679606
MESH:D019465 Craniofacial Abnormalities nitrofen 3.9211405365
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.9220055451 15322242 10048152
MESH:D019465 Craniofacial Abnormalities Tretinoin 3.9216925845 17551590 9224671 10589399 9142499 14991402 9211117 9664655 8800419 9125849
MESH:D003456 Cryptorchidism vinclozolin 4.3214966744
MESH:D003556 Cystitis Hydrochloric Acid 5.4719279288 12599022 20719367 12853844
MESH:D018856 Cystitis, Interstitial Hydrochloric Acid 5.8117714534
MESH:D017449 Dermatitis, Allergic Contact Toluene 2,4-Diisocyanate 4.0912956900 18759878 15491423
MESH:D003877 Dermatitis, Contact Toluene 2,4-Diisocyanate 4.7717010967
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6617107852
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 1.5320420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7411462148
MESH:D004417 Dyspnea Oxygen 4.8320016425
MESH:D004487 Edema Bleomycin 11.6017118201
MESH:D004487 Edema Tetrachlorodibenzodioxin 11.6012711302 11000095
MESH:D004487 Edema Tetradecanoylphorbol Acetate 11.608113982 8273558 15177302 9599246 16716910 7812673 11698051
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 11.9515322242 18230668 16714409
MESH:D004489 Edema, Cardiac Tretinoin 11.9518230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.1712538720
MESH:D016889 Endometrial Neoplasms Tretinoin 3.0916569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.009294722 10568697
MESH:D004802 Eosinophilia Toluene 2,4-Diisocyanate 4.648156442
MESH:D004935 Esophageal Diseases Hydrochloric Acid 5.7819566590
MESH:D004941 Esophagitis Hydrochloric Acid 5.9912928072
MESH:D004942 Esophagitis, Peptic Hydrochloric Acid 6.0220516732 14621274 11346197
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.7811564622
MESH:D005124 Eye Abnormalities Tretinoin 8.789664655 16938888
MESH:D005128 Eye Diseases Toluene 2,4-Diisocyanate 5.7418447907
MESH:D005234 Fatty Liver Ethinyl Estradiol 2.8015345470
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.4411858732
MESH:D005355 Fibrosis Hydrochloric Acid 21.2018497604
MESH:D005355 Fibrosis Terbutaline 21.2015467267
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 21.2020067830
MESH:D005355 Fibrosis Tretinoin 21.2017994277
MESH:D005739 Gas Poisoning Hydrochloric Acid 12.2012378975
MESH:D005739 Gas Poisoning Oxygen 12.2020016425
MESH:D005764 Gastroesophageal Reflux Hydrochloric Acid 5.3120516732 20616304 19951613 19957777 12212954 20545468
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.9316973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.3016417039
MESH:D005909 Glioblastoma Tretinoin 2.9917312396
MESH:D005911 Gliosis Paraquat 5.1611124998
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5910696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.1716096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.1616084493
MESH:D006356 Heartburn Hydrochloric Acid 5.7819566590
MESH:D006330 Heart Defects, Congenital nitrofen 11.2416080930
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 11.2410048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 11.2414991402 9664655
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3211000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.8816120746 15340226 12621046
MESH:D006548 Hernia, Diaphragmatic nitrofen 3.9318958481 16080930 17270546 7760232 11051153 15793718 17618886 12194112 10898224 12505043 10541330 15136996 12759764 16490937 9859898 8863223 12021965 11057544 12904592 12547725 9476886 17245593 10359170 16473863 12746050 15756563 9575882 12407540 7576705 11076806 9473106 15185205 15707848 10370016 11685700 15088113 10898222 11584395 10370017 10693666 10646786 11588001 15578192 18280292 15764645 16720372 7520565 11329586 9698600 16863852 11409163 16292651 18280291
MESH:D006689 Hodgkin Disease Bleomycin 4.3515147373 17606976 18501091
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.0516959395 18606429 8697196 15340226 16354765
MESH:D006930 Hyperalgesia Tretinoin 3.1916870215
MESH:D006940 Hyperemia Hydrochloric Acid 5.6412646421
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.5516778211
MESH:D006967 Hypersensitivity Toluene 2,4-Diisocyanate 4.5810880147 11019492
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9018850075 18670907
MESH:D006975 Hypertension, Portal Hydrochloric Acid 5.3316984587
MESH:D006976 Hypertension, Pulmonary Hydrochloric Acid 4.4419262391
MESH:D006985 Hyperventilation Terbutaline 6.0610895896
MESH:D007008 Hypokalemia Terbutaline 6.0817292646
MESH:D007021 Hypospadias Ethinyl Estradiol 3.8016945680 16569931
MESH:D007022 Hypotension Hydrochloric Acid 4.7411574821
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4412013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 11.1617937319
MESH:D007248 Infertility, Male Paraquat 11.164850670
MESH:D007248 Infertility, Male vinclozolin 11.1616467254
MESH:D007249 Inflammation Bleomycin 12.0217118201
MESH:D007249 Inflammation Hydrochloric Acid 12.0211574821
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 12.0212200463 12878042
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 12.0215177302 8273558 7562506 11698051 7812673
MESH:D007410 Intestinal Diseases Hydrochloric Acid 10.0811574821
MESH:D007410 Intestinal Diseases Tretinoin 10.0817994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.8716580747
MESH:D007569 Jaw Abnormalities Tretinoin 9.8715992940 17551590
MESH:D007818 Laryngeal Diseases Hydrochloric Acid 6.3616498863
MESH:D007826 Laryngismus Hydrochloric Acid 6.3611510729
MESH:D053609 Lethargy Terbutaline 6.3110895896
MESH:D007938 Leukemia Tretinoin 2.7617143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.6819285840 16482212 16932348
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0719850784 16294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.1417339181 17506722 17368321 19029980 19035177 16935935 16331271 17301526 19642359 19225113 9834237 17649720 17712046 17294898 16891316 17217047 17361223 16788101 17107899 12679006 16766008 16823087 19075265 15748426 16140955
MESH:D007984 Leydig Cell Tumor vinclozolin 4.7216417039
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.299224671
MESH:D008103 Liver Cirrhosis Hydrochloric Acid 4.0616984587
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 2.3012878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 2.3018397230 16248980
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 1.7116984957
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 2.0912151625
MESH:D008171 Lung Diseases Hydrochloric Acid 8.2616784557
MESH:D008171 Lung Diseases nitrofen 8.269859898 16863852 17245593 9614859
MESH:D055370 Lung Injury Hydrochloric Acid 21.7819644408 18339021 15607125 18497604 19262391 15044056 17627322 18573544 15090967 21311175 11395602 16129981 21114838 20597076
MESH:D055370 Lung Injury Oxygen 21.7818339021
MESH:D055370 Lung Injury S-methylisothiopseudouronium 21.7818573544
MESH:D055370 Lung Injury Sucralfate 21.7818573544
MESH:D008175 Lung Neoplasms marker/mechanism 14522914 15136449
MESH:D008175 Lung Neoplasms Bleomycin 3.646189445
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.6419555203 11884234
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 3.6411807781
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 3.348985016
MESH:D008527 Medulloblastoma Tretinoin 2.7817453147
MESH:D008545 Melanoma Bleomycin 3.7815577320
MESH:D008545 Melanoma Tretinoin 3.7816752155
MESH:D008591 Meningomyelocele Tretinoin 4.4116940565
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.0717596541
MESH:D009203 Myocardial Infarction Hydrochloric Acid 6.9718534312
MESH:D009203 Myocardial Infarction S-methylisothiopseudouronium 6.9710090345
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0012213967
MESH:D009369 Neoplasms Tretinoin 2.4016594593 16946489
MESH:D009374 Neoplasms, Experimental Toluene 2,4-Diisocyanate 4.721670384
MESH:D009410 Nerve Degeneration Paraquat 3.7016893418
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.4614600291
MESH:D009421 Nervous System Malformations Tretinoin 9.469125849
MESH:D009436 Neural Tube Defects Tretinoin 3.049142499
MESH:D007752 Obstetric Labor, Premature Terbutaline 6.1114998686
MESH:D009784 Occupational Diseases Hydrochloric Acid 9.7912378975
MESH:D009784 Occupational Diseases Toluene 2,4-Diisocyanate 9.7912585506 11077013 6091946 8156442 18394133 3040596 6091945
MESH:D010051 Ovarian Neoplasms Tretinoin 2.3416936753
MESH:D010146 Pain Tretinoin 2.8816870215
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 5.4915976015
MESH:D010190 Pancreatic Neoplasms Tretinoin 5.4915976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6711578682
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 4.2818922899 12065085 8330346 18404319
MESH:D010300 Parkinson Disease Paraquat 2.8011181820 16510128 16140633 15451049 12911755 11445065 11124998 15824117
MESH:D010302 Parkinson Disease, Secondary Paraquat 4.4216190885
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.2512520081
MESH:D011014 Pneumonia Bleomycin 11.4118024389 16317386 17071938
MESH:D011014 Pneumonia Paraquat 11.4112504350
MESH:D011015 Pneumonia, Aspiration Hydrochloric Acid 19.6215970105 18573544 15607125 18497604
MESH:D011015 Pneumonia, Aspiration S-methylisothiopseudouronium 19.6218573544
MESH:D011015 Pneumonia, Aspiration Sucralfate 19.6218573544
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5418163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.4611896295 11222880 11399792 11118676
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 9.4618220299 19015723 18042343
MESH:D011469 Prostatic Diseases vinclozolin 4.9318220299
MESH:D011472 Prostatitis vinclozolin 4.9318629315
MESH:D011507 Proteinuria Tretinoin 3.5916636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.3015861022 16919318
MESH:D011625 Pterygium Tretinoin 4.7816723453
MESH:D001261 Pulmonary Atelectasis Hydrochloric Acid 6.0220597076
MESH:D011654 Pulmonary Edema Bleomycin 18.3915808516
MESH:D011654 Pulmonary Edema Hydrochloric Acid 18.3915090967
MESH:D011654 Pulmonary Edema Terbutaline 18.3910903255
MESH:D011657 Pulmonary Eosinophilia Toluene 2,4-Diisocyanate 5.6214606601
MESH:D011658 Pulmonary Fibrosis Bleomycin 6.1918162602 16314464 21435439 15541506 17177178 12624602 15322207 14609568 18008008 17241526 17434272 11554783 12574379 16115399
MESH:D011658 Pulmonary Fibrosis Paraquat 6.1916324872 17997886
MESH:D012128 Respiratory Distress Syndrome, Adult Hydrochloric Acid 21.6018339021 17627322 18549715 16129981 16784557
MESH:D012128 Respiratory Distress Syndrome, Adult Oxygen 21.6018339021 17627322
MESH:D012128 Respiratory Distress Syndrome, Adult Paraquat 21.6011700416
MESH:D012128 Respiratory Distress Syndrome, Adult Terbutaline 21.602878809
MESH:D012130 Respiratory Hypersensitivity Toluene 2,4-Diisocyanate 4.4216940033 7692837 20219652
MESH:D012133 Respiratory Paralysis Hydrochloric Acid 6.3611510729
MESH:D012135 Respiratory Sounds Paraquat 4.0411874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8218990726
MESH:D012140 Respiratory Tract Diseases Hydrochloric Acid 11.2120516732
MESH:D012140 Respiratory Tract Diseases Toluene 2,4-Diisocyanate 11.2118447907
MESH:D012162 Retinal Degeneration Paraquat 3.8516458197
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.0816116481 16283617
MESH:D012220 Rhinitis Toluene 2,4-Diisocyanate 4.5619050374
MESH:D012221 Rhinitis, Allergic, Perennial Toluene 2,4-Diisocyanate 5.2812617775 15015336
MESH:D006255 Rhinitis, Allergic, Seasonal Toluene 2,4-Diisocyanate 5.5119075512
MESH:D012772 Shock, Septic Terbutaline 5.483431524
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.4516192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 9.4511807781 8985016 8330346 12065085 18404319
MESH:D012878 Skin Neoplasms Tretinoin 9.4516467112
MESH:D012912 Sneezing Toluene 2,4-Diisocyanate 5.5119050374 19075512
MESH:D013088 Spermatocele Ethinyl Estradiol 3.9416709447
MESH:D013274 Stomach Neoplasms Tretinoin 1.8017261132
MESH:D013276 Stomach Ulcer Hydrochloric Acid 8.4916755016 17189318 15309881
MESH:D013276 Stomach Ulcer Sucralfate 8.4915991576 10423059
MESH:D013398 Sudden Infant Death Oxygen 5.5412563064
MESH:D013610 Tachycardia Terbutaline 5.4810895896
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6011994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1315669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.9012697716
MESH:D013964 Thyroid Neoplasms Tretinoin 3.0116026305 17045167
MESH:D014062 Tongue Neoplasms Tretinoin 3.7716051514
MESH:D014376 Tuberculosis Tretinoin 3.2116040207
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.6616129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.2814692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.6116752155
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5912125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5214671159 15869587
MESH:D014820 Vitiligo Tretinoin 4.0416761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.2515886252
MESH:D015431 Weight Loss Bleomycin 5.6312624602
MESH:D009396 Wilms Tumor Tretinoin 3.9516287080
Pathway ID Pathway Name
REACT:20676 Cell junction organization
REACT:23853 Interactions of the immunoglobulin superfamily (IgSF) member proteins
KEGG:04145 Phagosome
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB02379 - Beta-D-Glucose Sweetening Agents
No data
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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