AutismKB 2.0

Annotation Detail for CSMD1


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Basic Information Top
Gene Symbol:CSMD1 ( KIAA1890 )
Gene Full Name: CUB and Sushi multiple domains 1
Band: 8p23.2
Quick LinksEntrez ID:64478; OMIM: 608397; Uniprot ID:CSMD1_HUMAN; ENSEMBL ID: ENSG00000183117; HGNC ID: 14026
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1831Prostate cancer
2125Bladder cancer
Desease Name
CHEMDEPENDENCY
multiple sclerosis
IMMUNE
smoking cessation
Desease Name
Multiple sclerosis
Emphysema-related traits
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CSMD1 mRNAaffects cotreatment|increases expression 18164116
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CSMD1 mRNAaffects cotreatment|increases expression 18164116
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000236 Adenoma beta-Naphthoflavone 7.7219389873
MESH:D000236 Adenoma Diethylnitrosamine 7.726695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 4.7916434500 19052882 19061943 17620307 17162532 18056438
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.1817474063
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 1.883581430 18691550 19394651 20007298 19519916 16328049 16807293 10737359 18506893 18494052 19335982 20101231 17761372 18056438 20084675 19107877 17428255 16681979 18785209 11831363 18393292 19418558 18788625 20727157 20514400 19822196 17173139 16698587 16288022 16935385 3084413 16779866 19208518 20524982 10672840 16540662 17978847 16569478 19539802 19383236 19052882 20512989 17055752 21159647 17138121 16502159 19171122 18978308 19701751 18665156 18210153 20935162 16878318 20432363 19919837 18971187 17162532 16830150 20214788
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 3.187505956 17174075 21159647 2727394
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 4.1519052882
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 2.2720387270
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 2.1519107877
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 6.1916302075
MESH:D005234 Fatty Liver Diethylnitrosamine 3.7321071580 20387270
MESH:D007249 Inflammation Diethylnitrosamine 2.5918785209
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 3.0519638242 20032147 18522880 18665156 18407596
MESH:D008107 Liver Diseases Diethylnitrosamine 2.1817034775
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 5.2619389873 21295105
MESH:D008113 Liver Neoplasms Diethylnitrosamine 5.2621047994 21071580 20492335 20118626 19812893 19551842 20452335 16942905 9163691 19255062 19833225 19850985 19638242 19996281 20405173 20501860 19499222 19427195 10737359 19256749 21278145 19294768 19254457 20583210 12771043 20434301 20137499 19073162 15175105 2422723 19426721 15885732 12112319 19642983 18754104 20101389 19690152 21167192 18644402 18977376 19090486 2862719 18978307 18648771
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 7.0818164116
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 7.0818308698 16267830 18253720 19009564 17854601 19539802 18164116 17942915 21159647 18093689 19519916 18775883 17174075 18544905 2563599 3124819 16842330 18079962 18282651 9362446 19126423 19004024
MESH:D008175 Lung Neoplasms Diethylnitrosamine 1.776695378 20970405 20512841 21163286
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.729029167 3581430
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.7820387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 6.1920387270
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.5516540662
MESH:D011230 Precancerous Conditions Diethylnitrosamine 4.022563599
MESH:D011565 Psoriasis marker/mechanism 20953187
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 1.7618456281
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 3.367505956
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA26947
  • No data
    Releated disease ID Related disease Name
    PA444987Multiple Sclerosis
    Releated drug ID Related drug Name
    PA450626nicotine
    Drug Bank Top

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      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018