AutismKB 2.0

Annotation Detail for C16orf58


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Basic Information Top
Gene Symbol:C16orf58 ( FLJ13868 )
Gene Full Name: chromosome 16 open reading frame 58
Band: 16p11.2
Quick LinksEntrez ID:64755; OMIM: NA; Uniprot ID:CP058_HUMAN; ENSEMBL ID: ENSG00000140688; HGNC ID: 25848
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C006632 arsenic trioxide arsenic trioxide results in increased expression of C16ORF58 mRNAincreases expression 15761015
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of C16ORF58 mRNAdecreases expression 20106945
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma arsenic trioxide 4.6619825857 11798837
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.6620464547 20127859
MESH:D000236 Adenoma Benzo(a)pyrene 2.906695378
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.8419183758
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 4.2216206674
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.9820146248 17474063
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.9411589617
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 1.9915553829 16217749 11135700 14691202 15073043
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.9419014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.6312490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1520419170
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8720501625
MESH:D023903 Coronary Restenosis arsenic trioxide 4.8612609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 1.9010525206
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.7015213294
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.7512903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.7516530937
MESH:D005234 Fatty Liver arsenic trioxide 3.8415073043
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.9416904648
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8720471113
MESH:D007938 Leukemia arsenic trioxide 3.0315070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 4.3512560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 5.1916972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.7914633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 4.3119077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1920471514 17050201 16467208 19850784 16968895
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.5115622746 12018890 15748426 17217047 16331271 17712046 16966277 12712474 19225113 17107899 16330433 16891316 15336539 15213294 11161223 9834237 19075265 11468182 17869043 19035177 17649720 16823087 12679006 16112521 19642359
MESH:D015458 Leukemia, T-Cell arsenic trioxide 5.0316882451
MESH:D008113 Liver Neoplasms arsenic trioxide 5.0414682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 5.0421137059 20195826
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 3.0120377131
MESH:D008133 Long QT Syndrome arsenic trioxide 3.7315213294
MESH:D008175 Lung Neoplasms arsenic trioxide 2.5211798837 19825857
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 2.5218569708 18520028 18816296 17053015 20064080 20464547 20135361 20869020 6695378
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.5716381670
MESH:D009101 Multiple Myeloma arsenic trioxide 3.4414977855 11468182 15949261 19549372 19417148
MESH:D009182 Mycosis Fungoides arsenic trioxide 5.7418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.3816882451 16105982
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.6316624393
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3611141357
MESH:D009436 Neural Tube Defects arsenic trioxide 3.4110525206
MESH:D010051 Ovarian Neoplasms arsenic trioxide 2.5216624393 12452020 19769630
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.6615580305
MESH:D010235 Paraganglioma arsenic trioxide 4.7719927285
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.0819131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.0817292933
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.6316646077
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.5519755658 10029692
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.4517007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.452093021 20155912
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.4719014326
MESH:D016171 Torsades de Pointes arsenic trioxide 4.8515213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 5.5512845720 20435036 11780464 12973940
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 5.5517053015
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018