Annotation Detail for ZNF574
Basic Information Top
| Gene Symbol: | ZNF574 ( FLJ22059,FP972 ) |
|---|---|
| Gene Full Name: | zinc finger protein 574 |
| Band: | 19q13.2 |
| Quick Links | Entrez ID:64763; OMIM: NA; Uniprot ID:ZN574_HUMAN; ENSEMBL ID: ENSG00000105732; HGNC ID: 26166 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| C051890 | irinotecan | irinotecan analog results in decreased expression of ZNF574 mRNA | decreases expression | 18927307 |
| D012402 | Rotenone | Rotenone results in increased expression of ZNF574 mRNA | increases expression | 19013527 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D003110 | Colonic Neoplasms | irinotecan | 2.65 | 17287894 17725105 | |
| MESH:D015179 | Colorectal Neoplasms | irinotecan | 2.37 | 16391804 17454858 17159606 16303861 18259882 15273666 18509181 | |
| MESH:D052016 | Mucositis | irinotecan | 5.89 | 17159606 | |
| MESH:D009362 | Neoplasm Metastasis | irinotecan | 3.32 | 18259882 | |
| MESH:D009410 | Nerve Degeneration | Rotenone | 4.26 | 18619942 17356569 15790535 | |
| MESH:D009447 | Neuroblastoma | irinotecan | 3.69 | 8761367 | |
| MESH:D017599 | Neuroectodermal Tumors | irinotecan | 5.62 | 8761367 | |
| MESH:D010300 | Parkinson Disease | Rotenone | 3.11 | 19114014 16412576 16140633 11535288 18191903 18619942 15451049 11445065 19232380 | |
| MESH:D020734 | Parkinsonian Disorders | Rotenone | 4.58 | 15574749 18197244 15795934 15927086 | |
| MESH:D013274 | Stomach Neoplasms | irinotecan | 2.36 | 15723263 |
| No data |