AutismKB 2.0

Annotation Detail for FNDC3B


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Basic Information Top
Gene Symbol:FNDC3B ( DKFZp686D14170,DKFZp762K137,FAD104,FLJ23399,MGC10002,PRO4979,YVTM2421 )
Gene Full Name: fibronectin type III domain containing 3B
Band: 3q26.31
Quick LinksEntrez ID:64778; OMIM: 611909; Uniprot ID:FND3B_HUMAN; ENSEMBL ID: ENSG00000075420; HGNC ID: 24670
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of FNDC3B mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of FNDC3B mRNAaffects expression 17562736
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of FNDC3B mRNAdecreases expression 20106945
20064835
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of FNDC3B mRNAdecreases expression 19150397
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of FNDC3B mRNAaffects cotreatment|affects expression 17602206
D003520 Cyclophosphamide FNDC3B protein affects the susceptibility to Cyclophosphamideaffects response to substance 16217747
D016572 Cyclosporine Cyclosporine results in increased expression of FNDC3B mRNAincreases expression 20106945
D004041 Dietary Fats Dietary Fats results in decreased expression of FNDC3B mRNAdecreases expression 18503570
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of FNDC3B mRNAaffects cotreatment|affects expression 17602206
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of FNDC3B mRNAaffects cotreatment|decreases expression 19619570
D004958 Estradiol Estradiol results in increased expression of FNDC3B mRNAincreases expression 19619570
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of FNDC3B mRNAaffects expression 17555576
D005472 Fluorouracil Fluorouracil results in decreased expression of FNDC3B mRNAdecreases expression 16510598
D005472 Fluorouracil FNDC3B protein affects the susceptibility to Fluorouracilaffects response to substance 16217747
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of FNDC3B mRNAaffects cotreatment|decreases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of FNDC3B mRNAincreases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of FNDC3B mRNAincreases expression 19465110
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of FNDC3B mRNAdecreases expression 15644576
D014635 Valproic Acid Valproic Acid results in increased expression of FNDC3B mRNAincreases expression 19101580
C025643 vinclozolin vinclozolin affects the expression of FNDC3B mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.4811752688 14514962 15322242
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 8.488875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.9619490988
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.0017505938
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 10.2220127859 20464547
MESH:D000230 Adenocarcinoma Estradiol 10.2211473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 10.2214692618
MESH:D000230 Adenocarcinoma Fluorouracil 10.2217638652
MESH:D000236 Adenoma Benzo(a)pyrene 6.686695378
MESH:D000236 Adenoma Diethylnitrosamine 6.686695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 10.2318056438 19061943 17162532 17620307 16434500 19052882
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 10.2316835633
MESH:D000550 Amblyopia Valproic Acid 5.3017688650
MESH:D000740 Anemia Fluorouracil 8.7717963324 15504547 16511603
MESH:D000740 Anemia Tetrachlorodibenzodioxin 8.7711748828
MESH:D000799 Angioedema Acetaminophen 3.9110982225
MESH:D001008 Anxiety Disorders Valproic Acid 8.9317497229
MESH:D001008 Anxiety Disorders vinclozolin 8.9319015723
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.1219183758
MESH:D001161 Arteriosclerosis Cyclophosphamide 17.3315014928
MESH:D001161 Arteriosclerosis Dietary Fats 17.3315238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 17.3311256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6815885639
MESH:D001321 Autistic Disorder Acetaminophen 1.8518445737
MESH:D001321 Autistic Disorder Valproic Acid 1.8518558336 18940202 15238991 18177632 18985861 17688650 20603192 18775368 18316065 17157402 17507914 16609825 18396377 19232924 19460635
MESH:D001714 Bipolar Disorder Valproic Acid 3.0920046352 17594078
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.0712125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.8515340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 8.0815746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 8.088888407
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 3.7917474063 20146248
MESH:D001943 Breast Neoplasms Cyclophosphamide 3.7911325840 17020986 18234424 12006526 17388661 18323546 16978400 15136595 15093573
MESH:D001943 Breast Neoplasms Dietary Fats 3.7920435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 3.7917474063
MESH:D001943 Breast Neoplasms Estradiol 3.7917289903 19861407 12948864 17261762 16675129 18497071 14630087 17018787
MESH:D001943 Breast Neoplasms Fluorouracil 3.7919217205 16110121 15136595 16595493 18357371 18608205 16557594
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 3.7920435547
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.5116111702
MESH:D002276 Carcinoid Tumor Fluorouracil 4.7316051944
MESH:D002277 Carcinoma Fluorouracil 8.2617121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 8.2616835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 11.4616705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 11.463084413
MESH:D006528 Carcinoma, Hepatocellular Cyclophosphamide 11.4619701751
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 11.4616878318 19107877 18788625 16540662 18971187 19519916 19418558 21159647 20514400 20935162 20512989 18056438 10737359 18978308 20727157 20084675 19052882 3581430 19539802 18506893 19171122 18665156 18393292 20101231 16328049 18785209 17138121 11831363 16502159 19335982 16288022 19394651 19701751 17428255 17978847 16830150 17761372 16807293 20214788 17162532 16935385 16698587 19208518 19383236 3084413 19822196 19919837 18691550 10672840 16681979 17173139 16779866 17055752 20007298 16569478 20432363 18210153 20524982 18494052
MESH:D006528 Carcinoma, Hepatocellular Estradiol 11.4616924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 11.4617088986 17971768 18930000 17045692 16799960 16332177
MESH:D018827 Carcinoma, Lewis Lung Cyclophosphamide 4.9416152834
MESH:D002292 Carcinoma, Renal Cell Cyclophosphamide 6.8516201981
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 6.8518695887
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.6720419170
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 4.6716757204 16280240 17066447 18986760
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3818850075 18670907 16120746
MESH:D002386 Cataract Acetaminophen 2.6010977129
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 16.1720889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 16.1712371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 16.1717174075 7505956 21159647 2727394
MESH:D002471 Cell Transformation, Neoplastic Estradiol 16.1718566989
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.7220734317
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 9.4119052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 9.4116835633
MESH:D002779 Cholestasis Cyclosporine 7.8419486331
MESH:D002779 Cholestasis Ethinyl Estradiol 7.8417681005 17333356 15861022 17110522 16919318 11677210 16105132
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1112621046 15340226 15668235 8697196 16354765
MESH:D003110 Colonic Neoplasms Fluorouracil 2.2415001691 17016597 16510598 18772588 17725105 17172411 16340194 17018589 17169374 17287894
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.0018802399 16303861 16391804 18509181 18288408 16331619 18949393 16524972 17255274 17454858 17016601 17401013 17594712 16282729 17094418 17695437 15148649 20501625 14970324 18383874 15289873 18448328
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0817141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4820055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Valproic Acid 2.4817688650 8888407 16575769
MESH:D003456 Cryptorchidism vinclozolin 4.3814966744
MESH:D003490 Cyanosis 2,4-dinitrotoluene 4.0618551238
MESH:D003556 Cystitis Cyclophosphamide 5.0512913760 16413132 10498854 16989017 18093676 12388444 18372110 11948286 12161096 10700343 15643279 17010015 16614059 16651033 18433785 18710439 15276878 17979934 18295254 18483878
MESH:D007644 Darier Disease Fluorouracil 4.8416733453
MESH:D003921 Diabetes Mellitus, Experimental Cyclophosphamide 4.0910990075 15331540 11751995
MESH:D003922 Diabetes Mellitus, Type 1 Cyclophosphamide 3.2318772604
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.2420387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.2417107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.4419279558
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 12.1021346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 12.1016109766 19416960 17522070 18071297 17906064 11739529 11287661 11461765 11834606 12540782 16227642 14550746 16781746 11743745 16177239 16485898 15619225 10663392 19085960 17562736 12958197 19370779 10915739 19164858 14725611 12594235 19739265 16393943 12705907 12392966 16081117 19420014 14986274 18713872 11421492 11529661 15968718 12153990 2444490 19923254 10774834
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 12.1019107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 12.1020420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 12.101733752 19641884
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.1619426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7811462148
MESH:D050171 Dyslipidemias Dietary Fats 3.4718367378
MESH:D004421 Dystonia Valproic Acid 4.081851702
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.4112711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.9615322242 16714409 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.2212538720
MESH:D016889 Endometrial Neoplasms Estradiol 3.0019148513 11473722 18566989
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.059294722 10568697
MESH:D004802 Eosinophilia Cyclophosphamide 4.2611006010
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.1917275665 3659116
MESH:D004828 Epilepsies, Partial Valproic Acid 3.983922381 16628512
MESH:D004827 Epilepsy Valproic Acid 2.9520417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 3.616426943 7562514 6254150
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.347750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.113659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.1816302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.2720426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 7.2716530937
MESH:D004938 Esophageal Neoplasms Fluorouracil 7.2716337965 16481741 15173087 17638652 16785472
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.0311564622
MESH:D005234 Fatty Liver Cyclosporine 24.9919224547
MESH:D005234 Fatty Liver Dietary Fats 24.9917967931 19004024 18296743 19551842
MESH:D005234 Fatty Liver Diethylnitrosamine 24.9920387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 24.9915345470
MESH:D005234 Fatty Liver Valproic Acid 24.9919224547 14986274
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5011858732
MESH:D005315 Fetal Diseases Valproic Acid 4.9516575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.178888407 18558336
MESH:D005355 Fibrosis Cyclosporine 14.9812168785 12639820
MESH:D005355 Fibrosis Dietary Fats 14.9818296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 14.9820067830
MESH:D005756 Gastritis Acetaminophen 3.7416983495
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.9816973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.3616417039
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.278708960
MESH:D005910 Glioma Fluorouracil 2.8816145905
MESH:D018316 Gliosarcoma Cyclophosphamide 5.5611389073
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.6610696789
MESH:D006086 Graft vs Host Disease Cyclophosphamide 5.0811014644 16376943 15172196
MESH:D006258 Head and Neck Neoplasms Fluorouracil 3.4018337622 15162350 15102660
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.4920471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.4911294989 10048152
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.4715720958
MESH:D006467 Hemophilia A Cyclophosphamide 5.3311918545
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3611000095
MESH:D006504 Hepatic Veno-Occlusive Disease Cyclophosphamide 5.6014986274
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.9312621046 16120746 15340226
MESH:D006558 Herpes Genitalis Estradiol 5.0915709030
MESH:D006689 Hodgkin Disease Cyclophosphamide 3.8116135485 17606976
MESH:D019584 Hot Flashes Estradiol 3.8117088409
MESH:D006849 Hydrocephalus Valproic Acid 4.9217688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.118697196 18606429 15340226 16354765 16959395
MESH:D006930 Hyperalgesia Acetaminophen 2.7216870215
MESH:D006937 Hypercholesterolemia Dietary Fats 3.6221332399
MESH:D006949 Hyperlipidemias Dietary Fats 3.6521332399
MESH:D006973 Hypertension Cyclosporine 4.9810903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.9818670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 3.8516945680 16569931
MESH:D007154 Immune System Diseases Cyclophosphamide 5.3916076520
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4912013081
MESH:D007248 Infertility, Male Cyclophosphamide 11.4016517039 7193160
MESH:D007248 Infertility, Male Ethinyl Estradiol 11.4017937319
MESH:D007248 Infertility, Male vinclozolin 11.4016467254
MESH:D007249 Inflammation Dietary Fats 8.3620412841
MESH:D007249 Inflammation Diethylnitrosamine 8.3618785209
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 8.3612878042 12200463
MESH:D007333 Insulin Resistance Dietary Fats 7.4318457598 11836018
MESH:D007333 Insulin Resistance Estradiol 7.4316393666 16627594
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.3616580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.5015604871
MESH:D007674 Kidney Diseases Acetaminophen 10.0712587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 10.078314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 10.0715618244
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 17.9616705839
MESH:D007680 Kidney Neoplasms Cyclosporine 17.9612371664
MESH:D007680 Kidney Neoplasms Estradiol 17.9615610895
MESH:D007680 Kidney Neoplasms Fluorouracil 17.9616985049
MESH:D007938 Leukemia Cyclophosphamide 3.5010602166
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Cyclophosphamide 3.5117658394 17802794 18587576 18172266 17296974 17008537
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Cyclophosphamide 4.1110373061
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.1516294345 17596541
MESH:D007970 Leukopenia Cyclophosphamide 5.0211830472 10052129
MESH:D007984 Leydig Cell Tumor vinclozolin 4.7816417039
MESH:D008103 Liver Cirrhosis Dietary Fats 6.6818296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.6818522880 18407596 18665156 19638242 20032147
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 2.2714716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 2.2712878042
MESH:D008107 Liver Diseases Acetaminophen 3.9319784758 11587558 16611625 16610002 12969438 12587719 19460945 19014921
MESH:D008107 Liver Diseases Diethylnitrosamine 3.9317034775
MESH:D017114 Liver Failure, Acute Acetaminophen 3.2616871587 17185352
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 14.3621137059 20195826
MESH:D008113 Liver Neoplasms Clofibric Acid 14.3617602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 14.3619294768 19426721 19090486 20492335 19551842 19996281 2422723 19642983 18648771 16942905 18754104 20405173 20452335 19427195 20101389 10737359 12771043 20501860 19254457 19638242 19812893 19850985 20137499 21278145 15175105 19256749 18977376 20583210 19499222 18978307 18644402 21071580 12112319 20118626 19690152 21047994 15885732 19833225 20434301 9163691 2862719 21167192 19255062 19073162
MESH:D008113 Liver Neoplasms Fluorouracil 14.3617045692 18383874 16603448 15113037
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 14.3616984957
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 5.8221159647 18079962 3124819 18544905 17854601 18775883 18253720 2563599 19519916 19539802 19126423 19009564 18164116 16267830 18308698 16842330 9362446 19004024 18093689 18282651 17942915 17174075
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 5.8212151625
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.3217228818
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 4.8620464547 18569708 20135361 18816296 17053015 20869020 18520028 6695378 20064080
MESH:D008175 Lung Neoplasms Diethylnitrosamine 4.8620970405 6695378 20512841 21163286
MESH:D008175 Lung Neoplasms Fluorouracil 4.8615246190
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.8619555203 11884234
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.8415086387
MESH:D008223 Lymphoma Cyclophosphamide 3.8612854902
MESH:D016393 Lymphoma, B-Cell Cyclophosphamide 4.6316675587
MESH:D008228 Lymphoma, Non-Hodgkin Cyclophosphamide 4.1911911406
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.5811807958 17203775 16891317 11408345
MESH:D020149 Manganese Poisoning Estradiol 4.5519453300
MESH:D008546 Melanoma, Experimental Acetaminophen 10.9719513568
MESH:D008546 Melanoma, Experimental Cyclophosphamide 10.9716388313
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.8516801185
MESH:D008881 Migraine Disorders Valproic Acid 3.2118803445 18765137
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 8.6016381670
MESH:D009062 Mouth Neoplasms Fluorouracil 8.6016757204 18986760
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.068888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.1717596541
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0412213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.3016810080
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.9118551238
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.589029167 3581430
MESH:D009369 Neoplasms Benzo(a)pyrene 8.4611141357
MESH:D009369 Neoplasms Cyclophosphamide 8.4618854779
MESH:D009369 Neoplasms Fluorouracil 8.4618600527 18239605 16928823
MESH:D009389 Neovascularization, Pathologic Estradiol 3.7817289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.5017954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.3118481113 19348381
MESH:D009421 Nervous System Malformations Estradiol 9.5916427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.5914600291
MESH:D009436 Neural Tube Defects Valproic Acid 3.1416359493 8888407
MESH:D009447 Neuroblastoma Cyclophosphamide 3.658761367 16115947 15176712
MESH:D019636 Neurodegenerative Diseases Acetaminophen 8.2618514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 8.2620387270
MESH:D017599 Neuroectodermal Tumors Cyclophosphamide 4.948761367 12837982
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.1820387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.4516436463
MESH:D009503 Neutropenia Cyclophosphamide 4.368291058
MESH:D009765 Obesity Dietary Fats 2.2921332399 20132043 17217161 20518802 16723640 19632207 18457598 18674790 11836018
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.4512819281 16049721
MESH:D009845 Oligospermia Cyclophosphamide 4.7616517039
MESH:D010051 Ovarian Neoplasms Estradiol 2.2319401270
MESH:D010146 Pain Acetaminophen 6.9316870215
MESH:D010146 Pain Cyclophosphamide 6.9312161096 18093676
MESH:D010190 Pancreatic Neoplasms Cyclophosphamide 8.7911332152
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 8.7916540662
MESH:D010190 Pancreatic Neoplasms Fluorouracil 8.7916500647 16929163 15113037 19003803
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.7211578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.3112520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5918163543
MESH:D011230 Precancerous Conditions Cyclosporine 9.0312371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 9.032563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Cyclophosphamide 3.8221297632
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 16.5511222880 11399792 11896295 11118676
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 16.5520603192
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 16.5518220299 18042343 19015723
MESH:D011469 Prostatic Diseases vinclozolin 4.9818220299
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.9120887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.0917292933
MESH:D011471 Prostatic Neoplasms Cyclophosphamide 2.0917136230
MESH:D011471 Prostatic Neoplasms Estradiol 2.0916740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.0919082440 18626508
MESH:D011472 Prostatitis vinclozolin 4.9818629315
MESH:D011537 Pruritus Ethinyl Estradiol 3.3616919318 15861022
MESH:D019310 Pseudolymphoma Valproic Acid 4.6011422049 12752131
MESH:D011565 Psoriasis Cyclosporine 2.2416882103
MESH:D011658 Pulmonary Fibrosis Cyclophosphamide 3.2916636934
MESH:D012004 Rectal Neoplasms Fluorouracil 4.0415538739 18722050 16160472 18286688
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8718990726
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.2119155313
MESH:D012559 Schizophrenia Valproic Acid 2.0715737665 19110320
MESH:D012595 Scleroderma, Systemic Cyclophosphamide 4.8516636934
MESH:D012640 Seizures 2,4-dinitrotoluene 6.0018551238
MESH:D012640 Seizures Valproic Acid 6.0014763951 17978042 11044598 11738929 1511512 15475178 3137016 16876388
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 5.5119755658 10029692
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.5116192470
MESH:D013088 Spermatocele Ethinyl Estradiol 4.0016709447
OMIM:102530 SPERMATOGENIC FAILURE 6 Cyclophosphamide 5.5616517039
MESH:D016135 Spinal Dysraphism Valproic Acid 3.8019490988
MESH:D013226 Status Epilepticus Valproic Acid 4.6012833885
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 3.372093021 20155912
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.3718456281
MESH:D013274 Stomach Neoplasms Fluorouracil 3.3716951190 17522103 18567086 16424979 15786421 18396642 19084572 17498489 19015929 17172411
MESH:D015173 Supratentorial Neoplasms Cyclophosphamide 5.1112837982
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1815669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.9612697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 3.007505956
MESH:D013978 Tibial Fractures Estradiol 4.7519048282
MESH:D014062 Tongue Neoplasms Fluorouracil 4.0216280240
MESH:D014178 Translocation, Genetic Valproic Acid 5.3017262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.573119515
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 8.4416049721
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 8.4417053015
MESH:D001749 Urinary Bladder Neoplasms Cyclophosphamide 8.4414692829
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.688888407
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.3710091137
MESH:D014581 Urticaria Acetaminophen 3.0110982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 3.9016803524
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.3314692618
MESH:D014605 Uveitis Cyclosporine 4.051336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.6612125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5714671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.3115886252
MESH:D015430 Weight Gain Dietary Fats 3.7616723640
MESH:D014985 Xerophthalmia Cyclosporine 4.5017120751
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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