AutismKB 2.0

Annotation Detail for IQCH


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:IQCH ( DKFZp434F2114,FLJ12476,NYDSP5 )
Gene Full Name: IQ motif containing H
Band: 15q23
Quick LinksEntrez ID:64799; OMIM: 612523; Uniprot ID:IQCH_HUMAN; ENSEMBL ID: ENSG00000103599; HGNC ID: 25721
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C006632 arsenic trioxide arsenic trioxide results in increased expression of IQCH mRNAincreases expression 15761015
C006780 bisphenol A bisphenol A affects the expression of IQCH mRNAaffects expression 20170705
D016572 Cyclosporine Cyclosporine results in increased expression of IQCH mRNAincreases expression 20106945
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma arsenic trioxide 2.3611798837 19825857
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 4.1516206674
MESH:D001862 Bone Resorption bisphenol A 4.3511985600
MESH:D001943 Breast Neoplasms bisphenol A 2.4217123778
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.8611589617
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 1.9811135700 14691202 15073043 16217749 15553829
MESH:D002278 Carcinoma in Situ bisphenol A 5.7317123778
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.7419014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.5712490120
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.8212371664
MESH:D002779 Cholestasis Cyclosporine 3.2419486331
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8720501625
MESH:D023903 Coronary Restenosis arsenic trioxide 4.7712609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 1.8910525206
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.6315213294
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.3912903497
MESH:D005234 Fatty Liver arsenic trioxide 9.4015073043
MESH:D005234 Fatty Liver Cyclosporine 9.4019224547
MESH:D005355 Fibrosis Cyclosporine 3.7912639820 12168785
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.8516904648
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.968708960
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 5.1615720958
MESH:D006973 Hypertension Cyclosporine 2.2310903974
MESH:D007333 Insulin Resistance bisphenol A 3.5616393666
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.3115604871
MESH:D007674 Kidney Diseases Cyclosporine 2.568314463 10903974 18776723
MESH:D007680 Kidney Neoplasms Cyclosporine 3.1212371664
MESH:D007938 Leukemia arsenic trioxide 3.0115070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 4.2812560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 5.0516972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.7514633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 4.2419077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1920471514 16968895 16467208 17050201 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.4816112521 16330433 19035177 17217047 11468182 15336539 19642359 15748426 15213294 16331271 17649720 12679006 17712046 15622746 16891316 12018890 16823087 19225113 9834237 16966277 17107899 11161223 12712474 17869043 19075265
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.9416882451
MESH:D008113 Liver Neoplasms arsenic trioxide 2.4714682389
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 2.9820377131
MESH:D008133 Long QT Syndrome arsenic trioxide 3.6915213294
MESH:D008175 Lung Neoplasms arsenic trioxide 1.8719825857 11798837
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.6516801185
MESH:D009101 Multiple Myeloma arsenic trioxide 3.4111468182 19417148 15949261 14977855 19549372
MESH:D009182 Mycosis Fungoides arsenic trioxide 5.5418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.3616105982 16882451
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.5416624393
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.3117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.7018481113 19348381
MESH:D009421 Nervous System Malformations bisphenol A 4.5616427766 11399458
MESH:D009436 Neural Tube Defects arsenic trioxide 3.3810525206
MESH:D010049 Ovarian Diseases bisphenol A 5.7311985600
MESH:D010051 Ovarian Neoplasms arsenic trioxide 2.5119769630 12452020 16624393
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.6415580305
MESH:D010235 Paraganglioma arsenic trioxide 4.6919927285
MESH:D011230 Precancerous Conditions Cyclosporine 3.6412371664
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 4.6910548101
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 4.6920887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.2519131511
MESH:D011471 Prostatic Neoplasms bisphenol A 3.2516740699
MESH:D011565 Psoriasis Cyclosporine 2.3416882103
MESH:D011629 Puberty, Precocious bisphenol A 5.5310548101
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.5416646077
MESH:D013274 Stomach Neoplasms arsenic trioxide 1.8617007042
MESH:D019966 Substance-Related Disorders bisphenol A 4.7216045194 16684133
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.4319014326
MESH:D016171 Torsades de Pointes arsenic trioxide 4.7015213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 2.6111780464 20435036 12845720 12973940
MESH:D014591 Uterine Diseases bisphenol A 5.8814652134
MESH:D014605 Uveitis Cyclosporine 4.851336536
MESH:D014985 Xerophthalmia Cyclosporine 5.3117120751
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved