AutismKB 2.0

Annotation Detail for IL25


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Basic Information Top
Gene Symbol:IL25 ( IL17E )
Gene Full Name: interleukin 25
Band: 14q11.2
Quick LinksEntrez ID:64806; OMIM: 605658; Uniprot ID:IL25_HUMAN; ENSEMBL ID: ENSG00000166090; HGNC ID: 13765
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04060Cytokine-cytokine receptor interaction
No data
No data
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1899Eosinophilia
2074Asthma
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D008070 Lipopolysaccharides Triclosan inhibits the reaction [Lipopolysaccharides results in increased expression of IL25 mRNA]decreases reaction|increases expression 20507366
D014260 Triclosan Triclosan inhibits the reaction [Lipopolysaccharides results in increased expression of IL25 mRNA]decreases reaction|increases expression 20507366
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury Lipopolysaccharides 4.6411850527 18653653
MESH:D000013 Congenital Abnormalities Triclosan 5.6119283420
MESH:D019446 Endotoxemia Lipopolysaccharides 5.2815328337 15821434 17637181
MESH:D005334 Fever Lipopolysaccharides 4.5211852909 9205823
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.8916366002
MESH:D007248 Infertility, Male Triclosan 4.7220821571
MESH:D007249 Inflammation Lipopolysaccharides 6.5817237260 17963957 12878042 17255318 9205823
MESH:D007249 Inflammation Triclosan 6.589584910 20507366
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 5.2417255318
MESH:D007970 Leukopenia Lipopolysaccharides 5.5815821434
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 2.2712878042
MESH:D055370 Lung Injury Lipopolysaccharides 4.7721114838
MESH:D008325 Mammary Neoplasms, Experimental Triclosan 4.4915358634
MESH:D011014 Pneumonia Lipopolysaccharides 5.4411605937 12224865
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 4.0310835634
MESH:D013921 Thrombocytopenia Lipopolysaccharides 4.6715821434
MESH:D013959 Thyroid Diseases Triclosan 7.0519910387
Pathway ID Pathway Name
KEGG:04060 Cytokine-cytokine receptor interaction
Pharmacogenomics Knowledge Base Top
Drug Bank Top

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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