AutismKB 2.0

Annotation Detail for AIDA


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Basic Information Top
Gene Symbol:AIDA ( C1orf80,FLJ12806,FLJ32421,RP11-378J18.7 )
Gene Full Name: axin interactor, dorsalization associated
Band: 1q41
Quick LinksEntrez ID:64853; OMIM: 612375; Uniprot ID:AIDA_HUMAN; ENSEMBL ID: ENSG00000186063; HGNC ID: 25761
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane affects the expression of AIDA mRNAaffects expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of AIDA mRNAaffects expression 17562736
C010327 salinomycin salinomycin results in decreased expression of AIDA mRNAdecreases expression 19682730
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.983712494
MESH:D000799 Angioedema Acetaminophen 4.7110982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.8911289319 1440618
MESH:D001943 Breast Neoplasms salinomycin 3.3119682730
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 2.973581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 2.973084413
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.847296757
MESH:D002386 Cataract Acetaminophen 2.8110977129
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 3.057505956
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 3.479022650 19486331
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 3.448970840 11906362 11298694 8156756 2524372 12868966 14531868 18759878
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 4.023621924 2952479
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 4.0518692083 9328219 16192314 7440962 1440618 6679447 8291058 9653073 18289764 9022650 11289319 6482804 18648102
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.0512540782 14725611 11743745 16227642 19739265 19370779 19416960 12958197 11529661 14986274 17906064 19085960 18071297 17562736 10915739 16109766 11739529 15968718 14550746 12392966 11461765 16485898 11287661 12705907 19164858 16393943 15619225 16781746 12153990 10774834 2444490 16081117 10663392 17522070 19923254 11421492 18713872 11834606 19420014 16177239 12594235
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.9619426721
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.193581430
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.896705139
MESH:D005756 Gastritis Acetaminophen 4.5416983495
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.577505956
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 4.106705139
MESH:D006930 Hyperalgesia Acetaminophen 3.0616870215
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.5915034207
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.898074119 9022650
MESH:D007674 Kidney Diseases Acetaminophen 2.4212587719 15629191
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 3.356582329
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.449327722 15034207
MESH:D008107 Liver Diseases Acetaminophen 1.7116611625 19460945 16610002 12969438 12587719 19784758 11587558 19014921
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6816871587 17185352
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 2.781399818 598648 3712494 6587162
MESH:D008325 Mammary Neoplasms, Experimental salinomycin 4.0319682730
MESH:D008546 Melanoma, Experimental Acetaminophen 4.2219513568
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.613581430
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 3.186679447
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2618514411
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.876482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.893988306
MESH:D010146 Pain Acetaminophen 2.7716870215
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 4.137296757
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 5.346228378
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.703692021
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 3.221399818 7505956 6582329 6587162 3712494
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 2.418074119
MESH:D014581 Urticaria Acetaminophen 3.5010982225
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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