AutismKB 2.0

Annotation Detail for ST3GAL3


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Basic Information Top
Gene Symbol:ST3GAL3 ( SIAT6,ST3GALII,ST3GalIII,ST3N )
Gene Full Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 3
Band: 1p34.1
Quick LinksEntrez ID:6487; OMIM: 606494; Uniprot ID:SIAT6_HUMAN; ENSEMBL ID: ENSG00000126091; HGNC ID: 10866
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa00601Glycosphingolipid biosynthesis - lacto and neolacto series
hsa00533Glycosaminoglycan biosynthesis - keratan sulfate
hsa01100Metabolic pathways
No data
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of ST3GAL3 mRNAaffects expression 21346803
D000643 Ammonium Chloride Ammonium Chloride affects the expression of ST3GAL3 mRNAaffects expression 16483693
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.4418287403
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 1.7916705839
MESH:D003490 Cyanosis 2,4-dinitrotoluene 4.7818551238
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 2.0618551238 21346803
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 3.4116705839
MESH:D009336 Necrosis 2,4-dinitrotoluene 4.7418551238
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.9312819281 16049721
MESH:D012640 Seizures 2,4-dinitrotoluene 2.8518551238
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 2.4316049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 5.2010091137
Pathway ID Pathway Name
KEGG:00533 Glycosaminoglycan biosynthesis - keratan sulfate
KEGG:00601 Glycosphingolipid biosynthesis - lacto and neolacto series
KEGG:01100 Metabolic pathways
KEGG:00514 Other types of O-glycan biosynthesis
Pharmacogenomics Knowledge Base Top
Drug Bank Top

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018