Annotation Detail for PAPOLG
Basic Information
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| Gene Symbol: | PAPOLG ( FLJ11805,FLJ12972,FLJ13482,FLJ14187,MGC133307,MGC133308 ) |
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| Gene Full Name: | poly(A) polymerase gamma |
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| Band: | 2p16.1 |
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| Quick Links | Entrez ID:64895; OMIM: NA; Uniprot ID:PAPOG_HUMAN; ENSEMBL ID: ENSG00000115421; HGNC ID: 14982 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| hsa03018 | RNA degradation |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C006253 |
pirinixic acid |
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of PAPOLG mRNA | affects binding|decreases expression|increases activity | 19710929
|
| D018038 |
Sodium Selenite |
Sodium Selenite results in increased expression of PAPOLG mRNA | increases expression | 18175754
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.72 | 18653653 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
4.37 | 16434500 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.70 | 19483382 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
3.19 | 19176532 |
| MESH:D019457 |
Chromosome Breakage |
|
Sodium Selenite |
5.52 | 15894690 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.61 | 18249437 |
| MESH:D003920 |
Diabetes Mellitus |
|
Sodium Selenite |
4.25 | 16285004 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Sodium Selenite |
2.38 | 15131321 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
3.02 | 12083418 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
3.31 | 19236843 20131406 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.81 | 20558911 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.76 | 16221962 19176532 19772884 18467677 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.69 | 20558911 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
8.31 | 16306350 |
| MESH:D007333 |
Insulin Resistance |
|
Sodium Selenite |
8.31 | 14714311 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
1.95 | 15890375 20007298 16377806 |
| MESH:D016393 |
Lymphoma, B-Cell |
|
Sodium Selenite |
4.66 | 14737004 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
4.27 | 16239165 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.30 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.33 | 16411023 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.14 | 17405874 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
1.90 | 20558911 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Sodium Selenite |
3.32 | 18760546 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.58 | 19058328 |
| Pathway ID |
Pathway Name |
|---|
| KEGG:03015 |
mRNA surveillance pathway |
Related Diseases/Disorders