AutismKB 2.0

Annotation Detail for BMP1


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Basic Information Top
Gene Symbol:BMP1 ( FLJ44432,PCOLC,PCP,PCP2,TLD )
Gene Full Name: bone morphogenetic protein 1
Band: 8p21.3
Quick LinksEntrez ID:649; OMIM: 112264; Uniprot ID:BMP1_HUMAN; ENSEMBL ID: ENSG00000168487; HGNC ID: 1067
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
Metabolism of lipids and lipoproteins
No data
Pathway IDPathway Name
P00052TGF-beta signaling pathway
Pathway IDPathway Name
500797HDL-mediated lipid transport
Related Diseases/Disorders Top
No data
Desease IDDesease Name
2041Myelofibrosis
No data
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C027576 4-hydroxy-2-nonenal 4-hydroxy-2-nonenal results in decreased expression of BMP1 mRNAdecreases expression 12419474
D000537 Aluminum Oxide Aluminum Oxide results in increased expression of BMP1 mRNAincreases expression 19464052
D000643 Ammonium Chloride Ammonium Chloride affects the expression of BMP1 mRNAaffects expression 16483693
D001205 Ascorbic Acid [Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP1 mRNAaffects cotreatment|increases expression 15994055
D016589 Astemizole Astemizole results in decreased expression of BMP1 mRNAdecreases expression 20221588
D001414 Bacitracin Bacitracin results in increased expression of BMP1 mRNAincreases expression 18289764
C031463 beta-glycerophosphoric acid [Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP1 mRNAaffects cotreatment|increases expression 15994055
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of BMP1 mRNAdecreases expression 12419474
D002101 Cacodylic Acid Cacodylic Acid results in decreased expression of BMP1 mRNAdecreases expression 17720352
D002995 Clofibric Acid Clofibric Acid affects the expression of BMP1 mRNAaffects expression 17602206
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of BMP1 mRNAaffects cotreatment|affects expression 17602206
D003314 Corn Oil Corn Oil affects the expression of BMP1 mRNAaffects expression 16360708
D002945 Cisplatin Cisplatin results in increased expression of BMP1 mRNAincreases expression 18289764
D004041 Dietary Fats Dietary Fats results in increased expression of BMP1 mRNAincreases expression 18457598
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of BMP1 mRNAaffects cotreatment|affects expression 17602206
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of BMP1 mRNAincreases expression 20360939
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of BMP1 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of BMP1 mRNAaffects cotreatment|increases expression 17942748
D005027 Ethylene Oxide Ethylene Oxide results in decreased activity of BMP1 proteindecreases activity 15224167
D005839 Gentamicins Gentamicins results in increased expression of BMP1 mRNAincreases expression 18289764
D009151 Mustard Gas Mustard Gas results in decreased expression of BMP1 mRNAdecreases expression 15674843
D010081 Oxazolone Oxazolone results in increased expression of BMP1 mRNAincreases expression 11379042
D010672 Phenytoin Phenytoin results in decreased expression of BMP1 mRNAdecreases expression 14741686
C006253 pirinixic acid pirinixic acid results in increased expression of BMP1 mRNAincreases expression 18301758
D011794 Quercetin Quercetin results in increased expression of BMP1 mRNAincreases expression 15309432
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of BMP1 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of BMP1 mRNAincreases expression 17942748
D014212 Tretinoin Tretinoin results in increased expression of BMP1 mRNAincreases expression 16604517
D014415 Tunicamycin Tunicamycin results in decreased expression of BMP1 mRNAdecreases expression 17127020
D014640 Vancomycin Vancomycin results in increased expression of BMP1 mRNAincreases expression 18289764
D002762 Cholecalciferol Cholecalciferol results in increased expression of BMP1 mRNAincreases expression 17170073
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenytoin 7.926195326 10563481 8986270 9677735 9118846 3425630
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.9215322242 11752688 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.3318287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.7117505938
MESH:D058186 Acute Kidney Injury Cisplatin 8.4615814532 12690470 17670903
MESH:D058186 Acute Kidney Injury Gentamicins 8.4611274264
MESH:D055371 Acute Lung Injury pirinixic acid 2.9118653653
MESH:D000230 Adenocarcinoma Cisplatin 4.2617638652 11798837
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.2614692618
MESH:D000236 Adenoma Diethylnitrosamine 2.7210737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 15.9517620307 19061943 19052882 16434500 18056438 17162532
MESH:D018248 Adenoma, Liver Cell pirinixic acid 15.9516434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 15.9516835633
MESH:D000505 Alopecia Tretinoin 3.4415955085
MESH:D000690 Amyotrophic Lateral Sclerosis 4-hydroxy-2-nonenal 3.9610965797
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.7511748828
MESH:D000743 Anemia, Hemolytic Quercetin 4.0317084956
MESH:D000799 Angioedema Astemizole 5.432883202
MESH:D001161 Arteriosclerosis Dietary Fats 9.1615238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.1611256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.7415885639
MESH:D001169 Arthritis, Experimental Tretinoin 6.7416412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2116292516
MESH:D001249 Asthma Mustard Gas 4.7410378619
MESH:D001249 Asthma Tretinoin 4.7416456186
MESH:D001260 Ataxia Telangiectasia Quercetin 4.7515336622
MESH:D050197 Atherosclerosis Phenytoin 3.7915136057
MESH:D001327 Autoimmune Diseases Cholecalciferol 10.3216142846
MESH:D001327 Autoimmune Diseases Quercetin 10.3219761891
MESH:D001471 Barrett Esophagus Tretinoin 4.1816935849
MESH:D001768 Blister Mustard Gas 4.9319167455
MESH:D001778 Blood Coagulation Disorders pirinixic acid 14.0819483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 14.0812125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 14.0816206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.5615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6215746008
MESH:D019046 Bone Marrow Neoplasms Cisplatin 4.6514601052
MESH:D001932 Brain Neoplasms Ethylene Oxide 5.3412562636
MESH:D001943 Breast Neoplasms Ascorbic Acid 5.6016443354
MESH:D001943 Breast Neoplasms Cacodylic Acid 5.6017474063
MESH:D001943 Breast Neoplasms Cisplatin 5.6019526202 18382427
MESH:D001943 Breast Neoplasms Dietary Fats 5.6020435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 5.6017474063
MESH:D001943 Breast Neoplasms Ethylene Oxide 5.6011921183 17162533
MESH:D001943 Breast Neoplasms Quercetin 5.6018628248
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 5.6020435547
MESH:D001943 Breast Neoplasms Tretinoin 5.6016166294 16443354 16873071
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.9315286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.7510378619 17687719
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.3616813970
MESH:D002105 Cadmium Poisoning Quercetin 5.3116962696
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6216835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.9316168501
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 6.3117982673
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 6.3120084675 21159647 16288022 18056438 16807293 20524982 18785209 19418558 20935162 18665156 19822196 16681979 17173139 20432363 19335982 16328049 19394651 19208518 17761372 18978308 16779866 11831363 17138121 20214788 19519916 16935385 17428255 16698587 19171122 20007298 3581430 16830150 17978847 20512989 18506893 19383236 18393292 20727157 18788625 16502159 19701751 18691550 19919837 10737359 16878318 20101231 19052882 17162532 10672840 16540662 20514400 18971187 19539802 19107877 17055752 16569478 3084413 18494052 18210153
MESH:D006528 Carcinoma, Hepatocellular Quercetin 6.3112508355 19519916
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 6.311917145
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 2.9612023789 16685392
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.7317234771
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 4.626189445 17066447 18337622
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 4.6216096774 16051514
MESH:D006332 Cardiomegaly Quercetin 6.3919794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.3918670907 18850075 16120746
MESH:D002386 Cataract Tretinoin 2.9617460283
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 2.702727394 7505956 21159647 17174075
MESH:D002493 Central Nervous System Diseases Phenytoin 5.074080065
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.3616129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.6919052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.6916835633
MESH:D002779 Cholestasis Ethinyl Estradiol 7.1916105132 17110522 16919318 15861022 17681005 17333356 11677210
MESH:D002779 Cholestasis pirinixic acid 7.1919176532
OMIM:601042 CHOREOATHETOSIS/SPASTICITY, EPISODIC Phenytoin 5.6411748493
MESH:D002822 Choriocarcinoma Tretinoin 4.9316461808
MESH:D002971 Cleft Lip Phenytoin 4.042227380
MESH:D002972 Cleft Palate Phenytoin 9.3610789828 2227380 6862529 6856622 3877104 1687470
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 9.3616354765 8697196 15668235 12621046 15340226
MESH:D002972 Cleft Palate Tretinoin 9.369407595
MESH:D003092 Colitis Tretinoin 3.4817035595
MESH:D003103 Coloboma Phenytoin 4.959212184
MESH:D003110 Colonic Neoplasms Quercetin 2.3819056647 15741050 17191121 17148506 16640504 19440933 11134977
MESH:D015179 Colorectal Neoplasms Cisplatin 2.7315273666
MESH:D015179 Colorectal Neoplasms Quercetin 2.7318095365 18852136
MESH:D003139 Common Cold Ascorbic Acid 5.2417323712
MESH:D000013 Congenital Abnormalities Phenytoin 8.7510627286
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 8.7514669216 17141729
MESH:D019465 Craniofacial Abnormalities Phenytoin 3.758986270 9212184 19952982
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.7510048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 3.759211117 17551590 16925845 9664655 9142499 14991402 9224671 9125849 8800419 10589399
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3218249437
MESH:D003877 Dermatitis, Contact Oxazolone 4.8812811023 15944321
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.5519496084
MESH:D003924 Diabetes Mellitus, Type 2 Ascorbic Acid 6.8416506275
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 6.8420387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.8417107852
MESH:D004244 Dizziness Astemizole 6.233105558
OMIM:607208 DRAVET SYNDROME Phenytoin 5.1611748493
MESH:D003875 Drug Eruptions Phenytoin 5.2715024534
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 3.5119107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.5120420201
MESH:D004362 Drug Toxicity Cisplatin 12.9112649298 12231392 15033597 19839026
MESH:D004362 Drug Toxicity Gentamicins 12.9111033412 15033597
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 12.9111462148
MESH:D050171 Dyslipidemias Dietary Fats 3.2918367378
MESH:C538011 Eales disease Ascorbic Acid 5.249068938
MESH:D004487 Edema Mustard Gas 10.259260866 11428631 11428647 11402378
MESH:D004487 Edema pirinixic acid 10.2512083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 10.2511000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 11.1716714409 15322242 18230668
MESH:D004489 Edema, Cardiac Tretinoin 11.1718230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.6412538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Phenytoin 8.6417654737
MESH:D016889 Endometrial Neoplasms Tretinoin 2.9616569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.829294722 10568697
MESH:D004802 Eosinophilia Astemizole 4.581355641
MESH:D004816 Epidermal Necrolysis, Toxic Phenytoin 4.9820235791
MESH:D004820 Epidermolysis Bullosa Phenytoin 6.001399206 6251365
MESH:D004828 Epilepsies, Partial Phenytoin 4.6911558140 17116037
MESH:D004827 Epilepsy Phenytoin 3.82821787 11434505 20417680
MESH:D017029 Epilepsy, Complex Partial Phenytoin 5.077750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenytoin 4.843659116
MESH:D004890 Erythema Mustard Gas 4.939357497
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.8916302075
MESH:D004938 Esophageal Neoplasms Cisplatin 2.7215464296 17638652 16785472 16481741 15173087
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.2811564622
MESH:D005124 Eye Abnormalities Tretinoin 8.289664655 16938888
MESH:D005234 Fatty Liver Dietary Fats 17.0617967931 19551842 19004024 18296743
MESH:D005234 Fatty Liver Diethylnitrosamine 17.0621071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 17.0615345470
MESH:D005234 Fatty Liver pirinixic acid 17.0620131406 19236843
MESH:D005313 Fetal Death Phenytoin 9.9910627286
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 9.9911858732
MESH:D005355 Fibrosis Dietary Fats 19.3218296743
MESH:D005355 Fibrosis Quercetin 19.3219474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 19.3220067830
MESH:D005355 Fibrosis Tretinoin 19.3217994277
MESH:D005499 Folliculitis Astemizole 5.691671328
MESH:D005885 Gingival Hyperplasia Phenytoin 5.449029455
MESH:D019214 Gingival Overgrowth Phenytoin 6.0016390469 14659971
MESH:D005909 Glioblastoma Quercetin 6.7719804834
MESH:D005909 Glioblastoma Tretinoin 6.7717312396
MESH:D005910 Glioma Quercetin 2.9717643826
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.3610696789
MESH:D006258 Head and Neck Neoplasms Cisplatin 7.4115102660 15464296
MESH:D006258 Head and Neck Neoplasms Tretinoin 7.4116096774
MESH:D034381 Hearing Loss Cisplatin 9.6519898482
MESH:D034381 Hearing Loss Gentamicins 9.6515968427 18024279 17868369 19130971
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.9316084493
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 4.2315464296
MESH:D006330 Heart Defects, Congenital Ascorbic Acid 10.5516080930
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 10.5511294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 10.5514991402 9664655
MESH:D006333 Heart Failure pirinixic acid 2.4020558911
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1311000095
MESH:D006529 Hepatomegaly pirinixic acid 7.5216221962 18467677 19176532 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.5216120746 15340226 12621046
MESH:D006548 Hernia, Diaphragmatic Ascorbic Acid 3.4016863852 16490937
MESH:D006689 Hodgkin Disease Cisplatin 3.4116170182 16200630
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.818697196 16354765 15340226 16959395 18606429
MESH:D006930 Hyperalgesia Tretinoin 3.0416870215
MESH:D053565 Hypercalciuria Gentamicins 5.4817652376
MESH:D006937 Hypercholesterolemia Dietary Fats 3.3921332399
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.3416778211
MESH:D006943 Hyperglycemia pirinixic acid 8.5820558911
MESH:D006943 Hyperglycemia Quercetin 8.5818262572 11834736
MESH:D020138 Hyperhomocysteinemia Phenytoin 4.4810459572
MESH:D006949 Hyperlipidemias Dietary Fats 3.4021332399
MESH:D006968 Hypersensitivity, Delayed Corn Oil 5.5811484837
MESH:D006973 Hypertension Quercetin 4.9318356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.9318850075 18670907
MESH:D007021 Hypospadias Ethinyl Estradiol 3.5816569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.2512013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.3417937319
MESH:D007249 Inflammation Dietary Fats 10.9920412841
MESH:D007249 Inflammation Diethylnitrosamine 10.9918785209
MESH:D007249 Inflammation Mustard Gas 10.9911428647 11428631 9260866 16001271 11428620 11402378 17524151 9357497 8975870
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 10.9912878042 12200463
MESH:D007251 Influenza, Human Quercetin 4.2816624496
MESH:D007333 Insulin Resistance Dietary Fats 6.7611836018 18457598
MESH:D007333 Insulin Resistance pirinixic acid 6.7616306350
MESH:D007410 Intestinal Diseases Tretinoin 3.5417994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.2516580747
MESH:D007569 Jaw Abnormalities Tretinoin 9.2517551590 15992940
MESH:D007627 Keloid Quercetin 4.7317086741
MESH:D007673 Kidney Cortex Necrosis Cisplatin 12.5515464296
MESH:D007673 Kidney Cortex Necrosis Gentamicins 12.5518842672
MESH:D007674 Kidney Diseases Bacitracin 17.7718289764
MESH:D007674 Kidney Diseases Cisplatin 17.7712231392 12649298 18289764 15190930 19839026
MESH:D007674 Kidney Diseases Gentamicins 17.7717934191 18289764 19349640
MESH:D007674 Kidney Diseases Quercetin 17.7716962696
MESH:D007674 Kidney Diseases Vancomycin 17.7718289764
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 11.2411231351
MESH:D007683 Kidney Tubular Necrosis, Acute Gentamicins 11.2411231351
MESH:D016773 Leishmaniasis, Cutaneous Gentamicins 4.2810219319
MESH:D007938 Leukemia Quercetin 6.0817468513
MESH:D007938 Leukemia Tretinoin 6.0817143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.4916482212 16932348 19285840
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0416294345 19850784 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.0119642359 16788101 17107899 16891316 19035177 17294898 16140955 12679006 17339181 17712046 17217047 17506722 15748426 17649720 17368321 19075265 16331271 16823087 16766008 17361223 16935935 9834237 19029980 17301526 19225113
MESH:D017513 Lichen Nitidus Astemizole 6.232563723
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.159224671
MESH:D008103 Liver Cirrhosis Dietary Fats 6.2218296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.2218522880 18407596 19638242 20032147 18665156
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.7115474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 4.7112741479
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.7112878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 4.7116248980 18397230
MESH:D008107 Liver Diseases Diethylnitrosamine 4.2917034775
MESH:D008107 Liver Diseases Phenytoin 4.2914986274
MESH:D008113 Liver Neoplasms Clofibric Acid 13.3117602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 13.3121278145 19073162 19426721 21047994 19499222 19833225 18644402 12112319 18754104 20452335 18977376 12771043 19638242 20405173 19690152 19812893 20101389 20137499 20501860 20492335 21167192 9163691 2862719 10737359 20118626 19256749 19090486 19551842 2422723 19255062 19642983 21071580 19294768 16942905 19254457 20583210 20434301 18648771 19996281 15885732 19427195 18978307 19850985 15175105
MESH:D008113 Liver Neoplasms pirinixic acid 13.3120007298 15890375 16377806
MESH:D008113 Liver Neoplasms Quercetin 13.3118980244
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 13.3116984957
MESH:D008114 Liver Neoplasms, Experimental Ascorbic Acid 13.0118544905
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 13.0119009564 18544905 16267830 18093689 19539802 18775883 18253720 3124819 21159647 18079962 18308698 17942915 18164116 16842330 19126423 18282651 2563599 17854601 19519916 9362446 17174075 19004024
MESH:D008114 Liver Neoplasms, Experimental Quercetin 13.0119519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 13.0112151625
MESH:D008133 Long QT Syndrome Astemizole 4.4218472280 11989578
MESH:D008171 Lung Diseases Ascorbic Acid 7.3216863852
MESH:D008171 Lung Diseases Mustard Gas 7.3218702808 18161513
MESH:D008175 Lung Neoplasms Ascorbic Acid 10.2616401635
MESH:D008175 Lung Neoplasms Cisplatin 10.2617225452 6189445 11798837
MESH:D008175 Lung Neoplasms Diethylnitrosamine 10.2621163286 6695378 20970405 20512841
MESH:D008175 Lung Neoplasms Ethylene Oxide 10.2617325976 12562636
MESH:D008175 Lung Neoplasms Mustard Gas 10.263148597 8781369
MESH:D008175 Lung Neoplasms Quercetin 10.2616280456
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 10.2619555203 11884234
MESH:D008288 Malaria Astemizole 4.5916816845
MESH:D015674 Mammary Neoplasms, Animal Ethylene Oxide 5.6712562636
MESH:D008325 Mammary Neoplasms, Experimental Ethylene Oxide 4.6211921183
MESH:D008527 Medulloblastoma Tretinoin 2.7017453147
MESH:D008545 Melanoma Cisplatin 3.3712393984 16432458 12374674 16248763 12883367 16809738 18332650 18505091 17023156 15577323 11135225 18176117 17761969
MESH:D008545 Melanoma Tretinoin 3.3716752155
MESH:D018328 Melanoma, Amelanotic Cisplatin 4.5515990972
MESH:D008591 Meningomyelocele Tretinoin 4.2016940565
MESH:D008607 Mental Retardation Phenytoin 3.599212184
MESH:D008654 Mesothelioma Cisplatin 3.1617638057
MESH:D009135 Muscular Diseases pirinixic acid 3.2816239165
MESH:D009137 Muscular Dystrophy, Animal Gentamicins 6.0418694830
MESH:D009190 Myelodysplastic Syndromes Tretinoin 2.9517596541
MESH:D009203 Myocardial Infarction pirinixic acid 5.4119151258
MESH:D009203 Myocardial Infarction Quercetin 5.4119595682
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.8412213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.8616411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 7.8619207477
MESH:D020191 Myoclonic Epilepsies, Progressive Phenytoin 5.2917484760
MESH:D009224 Myotonia Congenita Phenytoin 5.181896199
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.489029167 3581430
MESH:D009369 Neoplasms Cisplatin 10.9616773208
MESH:D009369 Neoplasms pirinixic acid 10.9617405874
MESH:D009369 Neoplasms Quercetin 10.9615185748
MESH:D009369 Neoplasms Tretinoin 10.9616946489 16594593
MESH:D009395 Nephritis, Interstitial Cisplatin 4.2615464296
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 8.7814600291
MESH:D009421 Nervous System Malformations Tretinoin 8.789125849
MESH:D009436 Neural Tube Defects Phenytoin 7.189118846
MESH:D009436 Neural Tube Defects Tretinoin 7.189142499
MESH:D009447 Neuroblastoma Cisplatin 3.338761367
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.1620387270
MESH:D017599 Neuroectodermal Tumors Cisplatin 4.478761367
MESH:D020078 Neurogenic Inflammation Quercetin 4.1517929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.8920387270
MESH:D009503 Neutropenia Mustard Gas 3.7616761898 7688884
MESH:D009759 Nystagmus, Pathologic Astemizole 6.236135121
MESH:D009765 Obesity Ascorbic Acid 7.1417217161
MESH:D009765 Obesity Dietary Fats 7.1416723640 21332399 11836018 19632207 18457598 18674790 20132043 17217161 20518802
MESH:D009765 Obesity pirinixic acid 7.1420558911
MESH:D010018 Osteomalacia Phenytoin 5.1817016548
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 4.0119495926
MESH:D010051 Ovarian Neoplasms Cisplatin 7.5715464296 6897625 17225452 19769630
MESH:D010051 Ovarian Neoplasms Quercetin 7.5719005980
MESH:D010051 Ovarian Neoplasms Tretinoin 7.5716936753
MESH:D010146 Pain Phenytoin 6.5715215642
MESH:D010146 Pain Tretinoin 6.5716870215
MESH:D010190 Pancreatic Neoplasms Cisplatin 11.6819003803
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 11.6816540662
MESH:D010190 Pancreatic Neoplasms Quercetin 11.6816965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 11.6815976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.4711578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.0212520081
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 4.0915464296
MESH:D010787 Photosensitivity Disorders 4-hydroxy-2-nonenal 5.2711550810
MESH:D010997 Pleural Neoplasms Cisplatin 5.1117638057
MESH:D011041 Poisoning Mustard Gas 3.5915727166
MESH:D017689 Polydactyly Phenytoin 4.859212184
MESH:D011115 Polyneuropathies Ethylene Oxide 5.958472653
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3418163543
MESH:D011230 Precancerous Conditions Corn Oil 14.4614668109
MESH:D011230 Precancerous Conditions Diethylnitrosamine 14.462563599
MESH:D011230 Precancerous Conditions Quercetin 14.4619056647
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 2.9611896295 11118676 11222880 11399792
MESH:D011471 Prostatic Neoplasms Cholecalciferol 3.8417024972
MESH:D011471 Prostatic Neoplasms Quercetin 3.8417292933 14715546
MESH:D011507 Proteinuria Gentamicins 8.8415033597
MESH:D011507 Proteinuria Tretinoin 8.8416636307
MESH:D011537 Pruritus Ethinyl Estradiol 8.7615861022 16919318
MESH:D011537 Pruritus Mustard Gas 8.7618058305
MESH:D019310 Pseudolymphoma Phenytoin 5.3112752131 1419762 8603615
MESH:D011625 Pterygium Tretinoin 4.5616723453
MESH:D011657 Pulmonary Eosinophilia Ascorbic Acid 5.1014606601
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.8417266442 17720292 17894541 10334151 17620002
MESH:D051437 Renal Insufficiency Cisplatin 9.9115464296
MESH:D051437 Renal Insufficiency Gentamicins 9.9115728788 17132701
MESH:D015427 Reperfusion Injury pirinixic acid 2.2819058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6218990726
MESH:D012173 Retinitis Gentamicins 6.0418644591
MESH:D012174 Retinitis Pigmentosa Ascorbic Acid 3.2516849425
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.8916283617 16116481
MESH:D012221 Rhinitis, Allergic, Perennial Astemizole 5.2010822083
MESH:D012512 Sarcoma, Ewing's Cisplatin 4.2114601052
MESH:D012554 Schistosomiasis japonica Quercetin 5.3116862918
MESH:D012640 Seizures Phenytoin 3.593137016 15946322 10029267 16876388 11044598 9844417 19919933 3691417
MESH:D012871 Skin Diseases Ascorbic Acid 5.1118709164
MESH:D012871 Skin Diseases Mustard Gas 5.1112880345 15451306 16961503
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 8.808532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 8.8016192470
MESH:D012878 Skin Neoplasms Tretinoin 8.8016467112
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 5.1115464296
MESH:D013088 Spermatocele Ethinyl Estradiol 3.7116709447
MESH:D013262 Stevens-Johnson Syndrome Phenytoin 4.9320235791
MESH:D013274 Stomach Neoplasms Cisplatin 3.3015958060 17522103 18396642
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.3018456281
MESH:D013274 Stomach Neoplasms Tretinoin 3.3017261132
MESH:D013276 Stomach Ulcer Ascorbic Acid 3.6918726076
MESH:D020521 Stroke Ascorbic Acid 4.1116517955 16403987
MESH:D013736 Testicular Neoplasms Cisplatin 4.4215464296 17225452
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.4111994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.9615669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.6712697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 6.607505956
MESH:D013964 Thyroid Neoplasms Tretinoin 6.6017045167 16026305
MESH:D014062 Tongue Neoplasms Tretinoin 3.5916051514
MESH:D016171 Torsades de Pointes Astemizole 4.988256756 9583453
MESH:D014376 Tuberculosis Tretinoin 3.0916040207
MESH:D001749 Urinary Bladder Neoplasms Cacodylic Acid 8.1115537745
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 8.1112973940 17225452 15464296
MESH:D001749 Urinary Bladder Neoplasms Quercetin 8.1116720314
MESH:D014581 Urticaria Astemizole 4.592568013 1683191 1976298 2147912 3097109 2568189 2883202 3080510 2859714 2565098 3134034 2885854
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 8.9116803524
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 8.9116129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 9.3814692618
MESH:D014594 Uterine Neoplasms Ethylene Oxide 9.3817325976 12562636
MESH:D014604 Uveal Neoplasms Tretinoin 4.3816752155
MESH:D014625 Vaginal Neoplasms Cisplatin 4.3915577323
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.3612125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.3315869587 14671159
MESH:D014717 Vertigo Astemizole 6.233105558
MESH:D015837 Vestibular Diseases Gentamicins 5.3018776599
MESH:D014820 Vitiligo Tretinoin 3.8416761959
MESH:D014839 Vomiting Cisplatin 4.4911897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.0215886252
MESH:D015430 Weight Gain Dietary Fats 3.5516723640
MESH:D009396 Wilms Tumor Tretinoin 3.7816287080
Pathway ID Pathway Name
REACT:22258 Metabolism of lipids and lipoproteins
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA25377
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    Releated drug ID Related drug Name
    PA450952phospholipids
    PA145007158torcetrapib
    PA450379mercaptopurine
    PA450428methotrexate
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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