AutismKB 2.0

Annotation Detail for SKI


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Basic Information Top
Gene Symbol:SKI ( SKV )
Gene Full Name: v-ski sarcoma viral oncogene homolog (avian)
Band: 1p36.33-p36.32
Quick LinksEntrez ID:6497; OMIM: 164780; Uniprot ID:SKI_HUMAN; ENSEMBL ID: ENSG00000157933; HGNC ID: 10896
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PWY66-11BMP Signalling Pathway
No data
Pathway IDPathway Name
Signaling by TGF beta
Signaling by BMP
Pathway IDPathway Name
200123BMP receptor signaling
200002Regulation of nuclear SMAD2/3 signaling
200130C-MYB transcription factor network
Pathway IDPathway Name
P00052TGF-beta signaling pathway
Pathway IDPathway Name
500592Signaling by BMP
500590Signaling by TGF beta
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1770Melanoma
1818Systemic scleroderma
1993Esophagus cancer
2051Leukemia
2157Scleroderma
2164Barrett's esophagus
No data
No data
Desease Name
1p36 deletion syndrome
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene results in decreased expression of SKI mRNAdecreases expression 20406850
D000082 Acetaminophen Acetaminophen affects the expression of SKI mRNAaffects expression 17562736
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of SKI mRNAdecreases expression 19150397
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of SKI mRNAincreases expression 20018196
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of SKI mRNAincreases expression 15056808
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of SKI mRNAincreases expression 15766595
C419708 gefitinib gefitinib results in increased expression of SKI mRNAincreases expression 16685379
D006830 Hydralazine [Hydralazine co-treated with Valproic Acid] results in decreased expression of SKI mRNAaffects cotreatment|decreases expression 17183730
D012643 Selenium Selenium results in increased expression of SKI mRNAincreases expression 19244175
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of SKI mRNAincreases expression 17586704
D014212 Tretinoin Tretinoin results in increased expression of SKI mRNAincreases expression 16604517
D014635 Valproic Acid [Hydralazine co-treated with Valproic Acid] results in decreased expression of SKI mRNAaffects cotreatment|decreases expression 17183730
D014810 Vitamin E Vitamin E results in increased expression of SKI mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.8314514962 15322242 11752688
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 8.838875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 4.0419490988
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.5316835633
MESH:D000505 Alopecia Tretinoin 3.7015955085
MESH:D000550 Amblyopia Valproic Acid 5.4117688650
MESH:D000686 Amyloidosis Diethylstilbestrol 4.6115469931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.0511748828
MESH:D000799 Angioedema Acetaminophen 4.0210982225
MESH:D001008 Anxiety Disorders Valproic Acid 3.6617497229
MESH:D001169 Arthritis, Experimental Tretinoin 3.1416412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2916292516
MESH:D001249 Asthma Tretinoin 2.3716456186
MESH:D001321 Autistic Disorder Acetaminophen 1.8518445737
MESH:D001321 Autistic Disorder Valproic Acid 1.8518775368 18396377 18985861 17157402 18558336 18316065 16609825 17507914 20603192 18940202 15238991 17688650 18177632 19232924 19460635
MESH:D001471 Barrett Esophagus Tretinoin 4.5316935849
MESH:D001714 Bipolar Disorder Valproic Acid 3.1320046352 17594078
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 9.3112125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 9.3116206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.9615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 8.2515746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 8.258888407
MESH:D001943 Breast Neoplasms Diethylstilbestrol 1.8815324884 17129689
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.8820435547
MESH:D001943 Breast Neoplasms Tretinoin 1.8816166294 16443354 16873071
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.7416813970
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 10.4015700767 16192424 3786805 18705752 15673190 16050911 16227642 16124888 15721981 16011737 16097048 10355542
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 10.4016050911
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8916835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.3316168501
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 9.0516705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 9.053084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 9.0518788625
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 9.0515948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 9.051917145
MESH:D002289 Carcinoma, Non-Small-Cell Lung gefitinib 3.9817290066 20005069 19233551 16230376 15496427 18347146
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 2.3216096774 16051514
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.4218850075 16120746 18670907
MESH:D002386 Cataract Acetaminophen 7.4310977129
MESH:D002386 Cataract Tretinoin 7.4317460283
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 6.896135515
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 6.8920889678
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.7416129372
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.7420734317
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.2616835633
MESH:D002822 Choriocarcinoma Tretinoin 5.3316461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.9016354765 8697196 12621046 15668235 15340226
MESH:D002972 Cleft Palate Tretinoin 5.909407595
MESH:D003092 Colitis Selenium 9.9717936198
MESH:D003092 Colitis Tretinoin 9.9717035595
MESH:D015179 Colorectal Neoplasms gefitinib 3.2417594712
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.1617141729 14669216
MESH:D019465 Craniofacial Abnormalities marker/mechanism 9284043
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 5.4910048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Tretinoin 5.4917551590 9224671 9664655 9211117 10589399 9142499 9125849 16925845 8800419 14991402
MESH:D019465 Craniofacial Abnormalities Valproic Acid 5.498888407 16575769 17688650
MESH:D019465 Craniofacial Abnormalities Vitamin E 5.4919769572
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.6812952375 16002989
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.1618551238
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6917107852
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 15.6721346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 15.6712594235 16781746 19370779 11834606 16485898 10915739 14550746 17906064 10774834 10663392 11743745 18071297 16109766 12705907 16081117 11287661 11739529 12153990 15619225 11461765 19085960 18713872 15968718 19416960 12392966 19739265 11421492 14986274 12958197 16227642 11529661 14725611 12540782 16393943 19420014 17522070 19164858 17562736 2444490 19923254 16177239
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 15.6717522070 10092053 21278145 3732212 9327722 7120509 15968718 2869522 16177239 19336974 15998439 7179309 16227642 15027814 10915739 3786805 11566570 6884620 7440962 6623471 19085960 4309450
MESH:D056486 Drug-Induced Liver Injury Selenium 15.6715131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 15.6720420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 15.671733752 19641884
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.2719426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.8411462148
MESH:D004421 Dystonia Valproic Acid 4.171851702
MESH:C538011 Eales disease Vitamin E 4.889068938
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.4811000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 12.5316714409 15322242 18230668
MESH:D004489 Edema, Cardiac Tretinoin 12.5318230668
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 4.8516402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 7.8216804899 15700306
MESH:D016889 Endometrial Neoplasms Tretinoin 7.8216569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.1210568697 9294722
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.2917275665 3659116
MESH:D004828 Epilepsies, Partial Valproic Acid 4.093922381 16628512
MESH:D004827 Epilepsy Valproic Acid 2.9918234410 20417680
MESH:D004832 Epilepsy, Absence Valproic Acid 3.686254150 6426943 7562514
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.447750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.223659116
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1020426865
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 9.1111564622
MESH:D005124 Eye Abnormalities Tretinoin 9.1116938888 9664655
MESH:D005234 Fatty Liver Carbon Tetrachloride 8.2417595544 12795759 19224547 15959796 16045604 61145 16239168 12631006
MESH:D005234 Fatty Liver Valproic Acid 8.2419224547 14986274
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.7216611131 16513791 16534752 15751030 16002989
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5911858732
MESH:D005315 Fetal Diseases Valproic Acid 5.0616575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.268888407 18558336
MESH:D005355 Fibrosis Carbon Tetrachloride 15.6018705752
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 15.6020067830
MESH:D005355 Fibrosis Tretinoin 15.6017994277
MESH:D005756 Gastritis Acetaminophen 3.8516983495
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 5.1016452187
MESH:D005909 Glioblastoma Tretinoin 3.0717312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.7710696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.2616096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.3316084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 11.4510048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 11.4514991402 9664655
MESH:D006330 Heart Defects, Congenital Vitamin E 11.4516080930
MESH:D006333 Heart Failure Selenium 3.1417162251
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.4411000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.7219900420 19110552
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.0315340226 16120746 12621046
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.7316863852 16490937
MESH:D019584 Hot Flashes Vitamin E 4.1514716179
MESH:D006849 Hydrocephalus Valproic Acid 5.0217688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.2215340226 8697196 16959395 18606429 16354765
MESH:D006930 Hyperalgesia Acetaminophen 7.9216870215
MESH:D006930 Hyperalgesia Tretinoin 7.9216870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.6916899240
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.7116778211
MESH:D006965 Hyperplasia Diethylstilbestrol 4.5712960047 14722030
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9418850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.2315338365
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 4.7616612254
MESH:D006976 Hypertension, Pulmonary gefitinib 4.7718424623
MESH:D017380 Hypertrophy, Right Ventricular gefitinib 6.3918424623
MESH:D007021 Hypospadias Diethylstilbestrol 4.7216002989
MESH:D007246 Infertility Diethylstilbestrol 4.4815036965
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 1.9112200463 12878042
MESH:D007251 Influenza, Human Selenium 11.5516624496
MESH:D007251 Influenza, Human Vitamin E 11.5516624496
MESH:D007410 Intestinal Diseases Tretinoin 3.9017994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 10.3016580747
MESH:D007569 Jaw Abnormalities Tretinoin 10.3017551590 15992940
MESH:D007674 Kidney Diseases Acetaminophen 6.1715629191 12587719
MESH:D007674 Kidney Diseases Vitamin E 6.1712488133
MESH:D007676 Kidney Failure, Chronic Selenium 3.9916518626
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 13.2216705839
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 13.2215003126 14681315 16762066
MESH:D007680 Kidney Neoplasms gefitinib 13.2218625569
MESH:D007859 Learning Disorders Diethylstilbestrol 4.2017184923
MESH:D007938 Leukemia Tretinoin 2.8217143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.8116482212 16932348 19285840
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.9417596541 16294345 19850784
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 3.9417596541 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.2216823087 17368321 17361223 16140955 19075265 12679006 16788101 19029980 17294898 19035177 17301526 17107899 16935935 19642359 16891316 17217047 17649720 16766008 17506722 15748426 16331271 17339181 19225113 9834237 17712046
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.389224671
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 2.8621278145 16221502 16239168 16943688 11408273 17174718 17334410 17157831 11903743
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 5.0516011737 18376398 18339082 17481882 17640975 20821823 18205269 16116963 18263696 15370692 12667390 15931870 13678700 11481614 10355542 17922224 12958196 18251166 17708605 17805973 18418968 16638106 17721639 16033810 17761835 18705752 15996030 15338365 17525996 15818738 18156304 18412020 12632514 14620537 17766677 12389079 14716833 17900296 12609069 18481824 18420326 14716496 15876570 12666154 17976157 15650968 15673190 16248980 12445421 17944888 12741479 18210741 16192424 16097048 18395095 15925388 15959796 15057751 15362042 12546737 18279442 16015684 16027843 12649538 18187930 18166357 12586293 14512876 17631135 18006644 15052691 14724832 15730626 12898905 12632512 17557913 15123356 18277467 18429990 18395914 17698563 17565644 15893842 18472094 12445418 18054572 14748882 17823541 16136751 18317297 17714472 17869086 18472332
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 5.0512878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 5.0516248980 18397230
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 5.0516169303
MESH:D008107 Liver Diseases Acetaminophen 3.9816610002 12587719 19460945 11587558 19784758 16611625 19014921 12969438
MESH:D008107 Liver Diseases Carbon Tetrachloride 3.9816964402 16246199 15830285 15720792 17285989
MESH:D017093 Liver Failure Carbon Tetrachloride 4.3015123358
MESH:D017114 Liver Failure, Acute Acetaminophen 9.7616871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 9.7616899240 14706259
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 11.037678174
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 11.0319294768
MESH:D008113 Liver Neoplasms Diethylstilbestrol 11.0315890375 16712894
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 11.0316984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 10.176135515 2876786 2876784
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 10.1712014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 10.1712151625
MESH:D008171 Lung Diseases Vitamin E 3.2516863852
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.4417228818
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 2.3311884234 19555203
MESH:D008175 Lung Neoplasms Vitamin E 2.3311062179
MESH:D008181 Lupus Nephritis Diethylstilbestrol 5.3015166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.5515700306
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.6916002989
MESH:D008325 Mammary Neoplasms, Experimental gefitinib 6.8318375820
MESH:D008325 Mammary Neoplasms, Experimental Selenium 6.8315318939
MESH:D008527 Medulloblastoma Tretinoin 2.8217453147
MESH:D008545 Melanoma Tretinoin 1.9516752155
MESH:D008546 Melanoma, Experimental Acetaminophen 3.7119513568
MESH:D008591 Meningomyelocele Tretinoin 4.5616940565
MESH:D008654 Mesothelioma Selenium 2.8315107826
MESH:D008881 Migraine Disorders Valproic Acid 3.2718803445 18765137
MESH:D009139 Musculoskeletal Abnormalities marker/mechanism 9284043
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.148888407
MESH:D009190 Myelodysplastic Syndromes Tretinoin 7.5917596541
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 7.5917596541
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.1112213967
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.0118551238 7678174
MESH:D009369 Neoplasms Diethylstilbestrol 5.3815313581
MESH:D009369 Neoplasms Tretinoin 5.3816594593 16946489
MESH:D009421 Nervous System Malformations Diethylstilbestrol 17.1611399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 17.1614600291
MESH:D009421 Nervous System Malformations Tretinoin 17.169125849
MESH:D009436 Neural Tube Defects marker/mechanism 9284043
MESH:D009436 Neural Tube Defects Tretinoin 7.549142499
MESH:D009436 Neural Tube Defects Valproic Acid 7.548888407 16359493
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.9618514411
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.5316049721
MESH:D010051 Ovarian Neoplasms Tretinoin 2.3716936753
MESH:D010146 Pain Acetaminophen 6.8916870215
MESH:D010146 Pain Tretinoin 6.8916870215
MESH:D010190 Pancreatic Neoplasms Tretinoin 2.5015976015
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.4212520081
MESH:D010900 Pituitary Diseases Diethylstilbestrol 5.3414722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.8115687265 16977796
MESH:D010954 Plasmacytoma Selenium 5.0615087411
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.6918163543
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 17.2117184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 17.2111399792 11118676 11222880 11896295
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 17.2120603192
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 2.8015846301 15046698 17136230
MESH:D011471 Prostatic Neoplasms gefitinib 2.8016685379 15651060 17914592
MESH:D011471 Prostatic Neoplasms Vitamin E 2.8015084515
MESH:D011507 Proteinuria Tretinoin 3.7216636307
MESH:D019310 Pseudolymphoma Valproic Acid 4.7112752131 11422049
MESH:D011625 Pterygium Tretinoin 4.9516723453
MESH:D011658 Pulmonary Fibrosis gefitinib 4.0418424623
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.9618990726
MESH:D012208 Rhabdomyosarcoma Tretinoin 11.2616116481 16283617
MESH:D012208 Rhabdomyosarcoma Valproic Acid 11.2619155313
MESH:D012559 Schizophrenia Valproic Acid 2.0819110320 15737665
MESH:D012640 Seizures 2,6-dinitrotoluene 6.1918551238
MESH:D012640 Seizures Valproic Acid 6.1917978042 14763951 11044598 16876388 3137016 1511512 11738929 15475178
MESH:D012871 Skin Diseases Vitamin E 2.4618709164
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.7216192470
MESH:D012878 Skin Neoplasms Tretinoin 5.7216467112
MESH:D013088 Spermatocele Diethylstilbestrol 4.8916709447 16002989
MESH:D016135 Spinal Dysraphism Valproic Acid 3.8619490988
MESH:D013226 Status Epilepticus Valproic Acid 4.7112833885
MESH:D013274 Stomach Neoplasms Tretinoin 1.8017261132
MESH:D020521 Stroke Vitamin E 3.6116517955
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.0812697716
MESH:D013964 Thyroid Neoplasms gefitinib 8.0016940797
MESH:D013964 Thyroid Neoplasms Tretinoin 8.0016026305 17045167
MESH:D014062 Tongue Neoplasms Tretinoin 3.8916051514
MESH:D014178 Translocation, Genetic Valproic Acid 5.4117262798
MESH:D014376 Tuberculosis Tretinoin 3.2916040207
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.673119515
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 5.3216049721
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 5.3216452187 17306315 16712894
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.788888407
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.4710091137
MESH:D014581 Urticaria Acetaminophen 3.0910982225
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 9.8616175088
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 9.8616129372
MESH:D014591 Uterine Diseases Diethylstilbestrol 5.3414652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 4.1915809267 16690809
MESH:D014604 Uveal Neoplasms Tretinoin 4.7816752155
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.5716513791 16002989
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.7712125929
MESH:D014820 Vitiligo Tretinoin 4.1816761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.4215886252
MESH:D009396 Wilms Tumor Tretinoin 4.0716287080
Pathway ID Pathway Name
REACT:12034 Signaling by BMP
REACT:6844 Signaling by TGF beta
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018