AutismKB 2.0

Annotation Detail for RSRC2


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Basic Information Top
Gene Symbol:RSRC2 ( FLJ11021 )
Gene Full Name: arginine/serine-rich coiled-coil 2
Band: 12q24.31
Quick LinksEntrez ID:65117; OMIM: NA; Uniprot ID:RSRC2_HUMAN; ENSEMBL ID: ENSG00000111011; HGNC ID: 30559
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1756Esophageal tumor
1993Esophagus cancer
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of RSRC2 mRNAaffects expression 17562736
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in increased expression of RSRC2 mRNAincreases expression 18687144
D005472 Fluorouracil Fluorouracil results in increased expression of RSRC2 mRNAincreases expression 15331170
D005472 Fluorouracil RSRC2 protein affects the susceptibility to Fluorouracilaffects response to substance 15331170
D012643 Selenium [Selenium co-treated with Vitamin E] results in decreased expression of RSRC2 mRNAaffects cotreatment|decreases expression 19244175
D012643 Selenium Selenium results in decreased expression of RSRC2 mRNAdecreases expression 19244175
D014810 Vitamin E [Selenium co-treated with Vitamin E] results in decreased expression of RSRC2 mRNAaffects cotreatment|decreases expression 19244175
D014810 Vitamin E Vitamin E results in decreased expression of RSRC2 mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Fluorouracil 2.4917638652
MESH:D000740 Anemia Fluorouracil 4.0617963324 16511603 15504547
MESH:D000799 Angioedema Acetaminophen 4.4510982225
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001943 Breast Neoplasms Fluorouracil 2.4415136595 18357371 18608205 16595493 16557594 16110121 19217205
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.4116050911
MESH:D002276 Carcinoid Tumor Fluorouracil 5.2816051944
MESH:D002277 Carcinoma Fluorouracil 3.8517121937
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 3.073084413
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 3.0718930000 17971768 16332177 16799960 17045692 17088986
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 3.1518695887
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 2.5716280240 17066447 16757204 18986760
MESH:D002386 Cataract Acetaminophen 2.7710977129
MESH:D003092 Colitis Selenium 4.2617936198
MESH:D003110 Colonic Neoplasms Fluorouracil 2.2817018589 15001691 18772588 17169374 17287894 16510598 17016597 17725105 17172411 16340194
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.0016391804 18949393 15289873 20501625 17594712 17094418 18448328 16331619 16282729 15148649 17016601 18509181 17695437 16303861 17401013 16524972 18802399 18383874 17454858 14970324 18288408 17255274
MESH:D019465 Craniofacial Abnormalities Vitamin E 1.9219769572
MESH:D007644 Darier Disease Fluorouracil 5.3316733453
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.0711461765 16393943 17906064 19164858 16177239 15619225 19739265 12594235 18071297 17522070 19416960 12392966 19085960 11529661 16781746 16485898 14725611 12958197 16109766 2444490 12153990 16081117 10915739 11739529 18713872 11421492 11287661 14550746 15968718 19923254 12705907 10663392 12540782 19420014 10774834 17562736 16227642 11834606 11743745 14986274 19370779
MESH:D056486 Drug-Induced Liver Injury Selenium 4.0715131321
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.7119426721
MESH:C538011 Eales disease Vitamin E 5.329068938
MESH:D004938 Esophageal Neoplasms Fluorouracil 2.5216337965 16481741 15173087 16785472 17638652
MESH:D005756 Gastritis Acetaminophen 4.2916983495
MESH:D005910 Glioma Fluorouracil 2.9816145905
MESH:D006258 Head and Neck Neoplasms Fluorouracil 3.6115102660 15162350 18337622
MESH:D006330 Heart Defects, Congenital Vitamin E 3.1516080930
MESH:D006333 Heart Failure Selenium 3.2717162251
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.8016490937 16863852
MESH:D019584 Hot Flashes Vitamin E 4.5814716179
MESH:D006930 Hyperalgesia Acetaminophen 2.9916870215
MESH:D007251 Influenza, Human Selenium 13.0916624496
MESH:D007251 Influenza, Human Vitamin E 13.0916624496
MESH:D007674 Kidney Diseases Acetaminophen 6.5812587719 15629191
MESH:D007674 Kidney Diseases Vitamin E 6.5812488133
MESH:D007676 Kidney Failure, Chronic Selenium 4.2616518626
MESH:D007680 Kidney Neoplasms Fluorouracil 3.6116985049
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 1.9016169303
MESH:D008107 Liver Diseases Acetaminophen 1.6919014921 16611625 19784758 12969438 12587719 11587558 16610002 19460945
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5816871587 17185352
MESH:D008113 Liver Neoplasms Fluorouracil 2.5815113037 17045692 18383874 16603448
MESH:D008171 Lung Diseases Vitamin E 3.4016863852
MESH:D055370 Lung Injury Asbestos, Crocidolite 4.5017365036
MESH:D008175 Lung Neoplasms Fluorouracil 2.6715246190
MESH:D008175 Lung Neoplasms Vitamin E 2.6711062179
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 5.3315086387
MESH:D008325 Mammary Neoplasms, Experimental Selenium 2.9715318939
MESH:D008546 Melanoma, Experimental Acetaminophen 4.0519513568
MESH:D008654 Mesothelioma Asbestos, Crocidolite 6.7216966607 16166281 18303189
MESH:D008654 Mesothelioma Selenium 6.7215107826
MESH:D009062 Mouth Neoplasms Fluorouracil 3.9016757204 18986760
MESH:D009369 Neoplasms Fluorouracil 2.7518600527 18239605 16928823
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1818514411
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.6616436463
MESH:D010146 Pain Acetaminophen 2.6916870215
MESH:D010190 Pancreatic Neoplasms Fluorouracil 2.7615113037 16929163 19003803 16500647
MESH:D010954 Plasmacytoma Selenium 5.5015087411
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 5.3810923243
MESH:D011471 Prostatic Neoplasms Fluorouracil 3.2818626508 19082440
MESH:D011471 Prostatic Neoplasms Vitamin E 3.2815084515
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 3.1417365031 15814490 17975199 17322281
MESH:D012004 Rectal Neoplasms Fluorouracil 4.3416160472 18286688 15538739 18722050
MESH:D012871 Skin Diseases Vitamin E 2.5118709164
MESH:D013274 Stomach Neoplasms Fluorouracil 2.0015786421 17498489 16951190 17522103 19084572 16424979 18567086 18396642 17172411 19015929
MESH:D020521 Stroke Vitamin E 3.8116517955
MESH:D014062 Tongue Neoplasms Fluorouracil 4.3416280240
MESH:D014581 Urticaria Acetaminophen 3.3810982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 4.2316803524
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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