AutismKB 2.0

Annotation Detail for SLC2A1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SLC2A1 ( DYT17,DYT18,GLUT,GLUT1,GLUT1DS,MGC141895,MGC141896,PED )
Gene Full Name: solute carrier family 2 (facilitated glucose transporter), member 1
Band: 1p34.2
Quick LinksEntrez ID:6513; OMIM: 138140; Uniprot ID:GTR1_HUMAN; ENSEMBL ID: ENSG00000117394; HGNC ID: 11005
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04920Adipocytokine signaling pathway
hsa05211Renal cell carcinoma
hsa05200Pathways in cancer
Pathway IDPathway Name
Metabolism of carbohydrates
Diabetes pathways
Transmembrane transport of small molecules
Metabolism of vitamins and cofactors
Integration of energy metabolism
Pathway IDPathway Name
200030HIF-2-alpha transcription factor network
200172HIF-1-alpha transcription factor network
200045Validated targets of C-MYC transcriptional activation
No data
Pathway IDPathway Name
500346Glucose transport
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1716Hypoglycemia
1856Obesity
1902Kidney failure
1904Diabetes mellitus
1934Cancer
2064Spinal dysraphism
2075Heart failure
2113Degenerative disc disease
2204Hemolytic anemia
Desease Name
diabetic nephropathy.
nephropathy
nephropathy in other diseases
RENAL
No data
Desease Name
GLUT1 deficiency syndrome 1
GLUT1 deficiency syndrome 2
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C496879 103D5R 103D5R results in decreased expression of SLC2A1 mRNAdecreases expression 15695405
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Phospholipids results in increased localization of SLC2A1 protein]decreases reaction|increases localization 15956784
C507553 4'-O-methylalpinumisoflavone 4'-O-methylalpinumisoflavone inhibits the reaction [Oxygen deficiency results in increased expression of SLC2A1 mRNA]decreases reaction|increases expression 19091749
C429845 7-hydroxyflavone 7-hydroxyflavone inhibits the reaction [SLC2A1 protein affects the transport of Glucose]affects transport|decreases reaction 14642735
C429845 7-hydroxyflavone 7-hydroxyflavone results in decreased activity of SLC2A1 proteindecreases activity 14642735
D000082 Acetaminophen Acetaminophen affects the expression of SLC2A1 mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen results in increased expression of SLC2A1 mRNAincreases expression 17522070
D000255 Adenosine Triphosphate Adenosine Triphosphate results in decreased stability of SLC2A1 proteindecreases stability 11420438
D000535 Aluminum Aluminum results in increased expression of SLC2A1 proteinincreases expression 16979867
D000584 Amiloride Amiloride promotes the reaction [Cyclosporine results in increased expression of SLC2A1 mRNA]increases expression|increases reaction 12081571
D000643 Ammonium Chloride Ammonium Chloride affects the expression of SLC2A1 mRNAaffects expression 16483693
C060817 apaziquone SLC2A1 protein results in decreased susceptibility to apaziquonedecreases response to substance 17520257
C006632 arsenic trioxide arsenic trioxide results in increased expression of SLC2A1 mRNAincreases expression 20458559
C006632 arsenic trioxide SLC2A1 protein results in increased import of arsenic trioxideincreases import 17064664
C006632 arsenic trioxide SLC2A1 protein results in increased import of arsenic trioxideincreases import 17064664
D001463 Barbiturates Barbiturates inhibits the reaction [SLC2A1 protein results in increased transport of Glucose]decreases reaction|increases transport 18455367
D001564 Benzo(a)pyrene Benzo(a)pyrene affects the expression of SLC2A1 mRNAaffects expression 20106945
C002791 bismuth tripotassium dicitrate bismuth tripotassium dicitrate results in increased expression of SLC2A1 mRNAincreases expression 15912405
C006780 bisphenol A bisphenol A results in increased expression of SLC2A1 mRNAincreases expression 12075121
15901920
D020001 1-Butanol 1-Butanol inhibits the reaction [Phospholipids results in increased localization of SLC2A1 protein]decreases reaction|increases localization 15956784
D019256 Cadmium Chloride Cadmium Chloride results in decreased expression of SLC2A1 mRNAdecreases expression 12760830
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of SLC2A1 mRNAaffects expression 17484886
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of SLC2A1 mRNAincreases expression 17522070
D002697 Chloral Hydrate Chloral Hydrate inhibits the reaction [SLC2A1 protein results in increased transport of Glucose]decreases reaction|increases transport 18455367
D002725 Chloroform Chloroform results in increased expression of SLC2A1 mRNAincreases expression 17522070
D002939 Ciprofloxacin Ciprofloxacin affects the localization of SLC2A1 mRNAaffects localization 19022360
D002939 Ciprofloxacin Ciprofloxacin results in decreased expression of SLC2A1 mRNAdecreases expression 19022360
C018021 cobaltous chloride cobaltous chloride results in increased expression of SLC2A1 mRNAincreases expression 7493931
D003345 Corticosterone Corticosterone results in increased expression of SLC2A1 mRNAincreases expression 15755911
D003506 Cyclofenil Cyclofenil inhibits the reaction [SLC2A1 protein affects the transport of Glucose]affects transport|decreases reaction 14642735
D003506 Cyclofenil Cyclofenil results in decreased activity of SLC2A1 proteindecreases activity 14642735
D003513 Cycloheximide [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SLC2A1 mRNAaffects cotreatment|increases expression 19684285
D016572 Cyclosporine Amiloride promotes the reaction [Cyclosporine results in increased expression of SLC2A1 mRNA]increases expression|increases reaction 12081571
D016572 Cyclosporine Cyclosporine results in increased expression of SLC2A1 mRNAincreases expression 12081571
D016572 Cyclosporine Cyclosporine results in increased expression of SLC2A1 proteinincreases expression 12081571
D016572 Cyclosporine Phloretin promotes the reaction [Cyclosporine results in increased expression of SLC2A1 mRNA]increases expression|increases reaction 12081571
D016572 Cyclosporine Phloretin promotes the reaction [Cyclosporine results in increased expression of SLC2A1 protein]increases expression|increases reaction 12081571
D016572 Cyclosporine SLC2A1 protein results in decreased susceptibility to Cyclosporinedecreases response to substance 12081571
D003571 Cytochalasin B Cytochalasin B inhibits the reaction [SLC2A1 protein results in increased transport of Glucose]decreases reaction|increases transport 8457197
D003606 Dacarbazine SLC2A1 protein results in decreased susceptibility to Dacarbazinedecreases response to substance 17520257
C004742 daidzein daidzein inhibits the reaction [SLC2A1 protein affects the transport of Glucose]affects transport|decreases reaction 14642735
C004742 daidzein daidzein results in decreased activity of SLC2A1 proteindecreases activity 14642735
D003975 Diazepam Diazepam inhibits the reaction [SLC2A1 protein results in increased transport of Glucose]decreases reaction|increases transport 18455367
D004041 Dietary Fats Dietary Fats results in increased expression of SLC2A1 mRNAincreases expression 18042831
D004054 Diethylstilbestrol Diethylstilbestrol inhibits the reaction [SLC2A1 protein affects the transport of Glucose]affects transport|decreases reaction 14642735
D004054 Diethylstilbestrol Diethylstilbestrol results in decreased activity of SLC2A1 proteindecreases activity 14642735
D004317 Doxorubicin Doxorubicin results in increased expression of SLC2A1 mRNAincreases expression 16595493
D004391 Dust Dust results in increased expression of SLC2A1 mRNAincreases expression 15735009
C045651 epigallocatechin gallate epigallocatechin gallate results in increased expression of SLC2A1 mRNAincreases expression 16988119
D004958 Estradiol Estradiol results in increased expression of SLC2A1 proteinincreases expression 15350188
D004958 Estradiol [Progesterone co-treated with Estradiol] results in decreased expression of SLC2A1 proteinaffects cotreatment|decreases expression 15350188
D000431 Ethanol Ethanol results in decreased expression of SLC2A1 mRNAdecreases expression 17920746
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of SLC2A1 mRNAincreases expression 17555576
17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SLC2A1 mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of SLC2A1 mRNAincreases expression 15901920
15576828
12075121
D019788 Fluorodeoxyglucose F18 SLC2A1 mRNA affects the uptake of Fluorodeoxyglucose F18affects uptake 16595493
D005472 Fluorouracil Fluorouracil results in decreased activity of SLC2A1 proteindecreases activity 16253763
D005472 Fluorouracil Fluorouracil results in decreased expression of SLC2A1 mRNAdecreases expression 16253763
D005472 Fluorouracil Fluorouracil results in increased expression of SLC2A1 mRNAincreases expression 16595493
D019833 Genistein Genistein inhibits the reaction [SLC2A1 protein affects the transport of Glucose]affects transport|decreases reaction 14642735
D019833 Genistein Genistein results in decreased activity of SLC2A1 proteindecreases activity 14642735
D019833 Genistein Genistein results in increased expression of SLC2A1 mRNAincreases expression 12075121
C100093 gentamicin C gentamicin C results in increased expression of SLC2A1 mRNAincreases expression 12927799
D005947 Glucose 7-hydroxyflavone inhibits the reaction [SLC2A1 protein affects the transport of Glucose]affects transport|decreases reaction 14642735
D005947 Glucose Barbiturates inhibits the reaction [SLC2A1 protein results in increased transport of Glucose]decreases reaction|increases transport 18455367
D005947 Glucose Chloral Hydrate inhibits the reaction [SLC2A1 protein results in increased transport of Glucose]decreases reaction|increases transport 18455367
D005947 Glucose Cyclofenil inhibits the reaction [SLC2A1 protein affects the transport of Glucose]affects transport|decreases reaction 14642735
D005947 Glucose Cytochalasin B inhibits the reaction [SLC2A1 protein results in increased transport of Glucose]decreases reaction|increases transport 8457197
D005947 Glucose daidzein inhibits the reaction [SLC2A1 protein affects the transport of Glucose]affects transport|decreases reaction 14642735
D005947 Glucose Diazepam inhibits the reaction [SLC2A1 protein results in increased transport of Glucose]decreases reaction|increases transport 18455367
D005947 Glucose Diethylstilbestrol inhibits the reaction [SLC2A1 protein affects the transport of Glucose]affects transport|decreases reaction 14642735
D005947 Glucose Genistein inhibits the reaction [SLC2A1 protein affects the transport of Glucose]affects transport|decreases reaction 14642735
D005947 Glucose Glucose results in increased stability of SLC2A1 proteinincreases stability 11420438
D005947 Glucose isoliquiritigenin inhibits the reaction [SLC2A1 protein affects the transport of Glucose]affects transport|decreases reaction 14642735
D005947 Glucose kaempferol inhibits the reaction [SLC2A1 protein affects the transport of Glucose]affects transport|decreases reaction 14642735
D005947 Glucose myricetin inhibits the reaction [SLC2A1 protein affects the transport of Glucose]affects transport|decreases reaction 14642735
D005947 Glucose naringenin inhibits the reaction [SLC2A1 protein affects the transport of Glucose]affects transport|decreases reaction 14642735
D005947 Glucose Phloretin inhibits the reaction [SLC2A1 protein affects the transport of Glucose]affects transport|decreases reaction 14642735
D005947 Glucose Quercetin inhibits the reaction [SLC2A1 protein affects the transport of Glucose]affects transport|decreases reaction 14642735
D005947 Glucose SLC2A1 protein results in increased transport of Glucoseincreases transport 8457197
18455367
D005947 Glucose Tamoxifen inhibits the reaction [SLC2A1 protein affects the transport of Glucose]affects transport|decreases reaction 14642735
D005947 Glucose Valproic Acid inhibits the reaction [SLC2A1 protein results in increased transport of Glucose]decreases reaction|increases transport 18455367
D005947 Glucose Glucose results in decreased expression of SLC2A1 mRNAdecreases expression 1727734
D005947 Glucose SLC2A1 protein results in increased transport of Glucoseincreases transport 12081571
C029424 hydrazine hydrazine results in increased expression of SLC2A1 mRNAincreases expression 15370871
D007052 Ibuprofen Ibuprofen results in decreased expression of SLC2A1 proteindecreases expression 12912967
C040920 isoliquiritigenin isoliquiritigenin inhibits the reaction [SLC2A1 protein affects the transport of Glucose]affects transport|decreases reaction 14642735
C040920 isoliquiritigenin isoliquiritigenin results in decreased activity of SLC2A1 proteindecreases activity 14642735
C006552 kaempferol kaempferol inhibits the reaction [SLC2A1 protein affects the transport of Glucose]affects transport|decreases reaction 14642735
C006552 kaempferol kaempferol results in decreased activity of SLC2A1 proteindecreases activity 14642735
D019325 3-O-Methylglucose Pentobarbital inhibits the reaction [SLC2A1 protein results in increased uptake of 3-O-Methylglucose]decreases reaction|increases uptake 10590023
D019325 3-O-Methylglucose Pentobarbital promotes the reaction [SLC2A1 gene polymorphism results in decreased uptake of 3-O-Methylglucose]decreases uptake|increases reaction 10590023
D019325 3-O-Methylglucose Phenobarbital inhibits the reaction [SLC2A1 protein results in increased uptake of 3-O-Methylglucose]decreases reaction|increases uptake 10590023
D019325 3-O-Methylglucose Phenobarbital promotes the reaction [SLC2A1 gene polymorphism results in decreased uptake of 3-O-Methylglucose]decreases uptake|increases reaction 10590023
D019325 3-O-Methylglucose SLC2A1 protein results in increased uptake of 3-O-Methylglucoseincreases uptake 10590023
C020300 monomethylarsonic acid SLC2A1 protein results in increased import of monomethylarsonic acidincreases import 17064664
C020300 monomethylarsonic acid SLC2A1 protein results in increased import of monomethylarsonic acidincreases import 17064664
C040015 myricetin myricetin inhibits the reaction [SLC2A1 protein affects the transport of Glucose]affects transport|decreases reaction 14642735
C040015 myricetin myricetin results in decreased activity of SLC2A1 proteindecreases activity 14642735
D019810 Sodium Azide Sodium Azide results in increased expression of SLC2A1 mRNAincreases expression 14578187
D015058 1-Naphthylisothiocyanate 1-Naphthylisothiocyanate results in increased expression of SLC2A1 mRNAincreases expression 17522070
C005273 naringenin naringenin inhibits the reaction [SLC2A1 protein affects the transport of Glucose]affects transport|decreases reaction 14642735
C005273 naringenin naringenin results in decreased activity of SLC2A1 proteindecreases activity 14642735
C022838 nickel chloride nickel chloride results in increased expression of SLC2A1 mRNAincreases expression 12839937
C029938 nickel sulfate nickel sulfate results in increased expression of SLC2A1 mRNAincreases expression 16100012
C002741 N-nitrosomorpholine N-nitrosomorpholine results in increased expression of SLC2A1 proteinincreases expression 7921415
8364915
D015242 Ofloxacin Ofloxacin affects the localization of SLC2A1 mRNAaffects localization 19022360
D015242 Ofloxacin Ofloxacin results in decreased expression of SLC2A1 mRNAdecreases expression 19022360
D010100 Oxygen 4'-O-methylalpinumisoflavone inhibits the reaction [Oxygen deficiency results in increased expression of SLC2A1 mRNA]decreases reaction|increases expression 19091749
D010100 Oxygen Oxygen deficiency results in increased expression of SLC2A1 mRNAincreases expression 10780954
7493931
D010100 Oxygen Rotenone inhibits the reaction [Oxygen deficiency results in increased expression of SLC2A1 mRNA]decreases reaction|increases expression 19091749
D010100 Oxygen SLC2A1 protein inhibits the reaction [Oxygen deficiency results in increased activity of MAPK8 protein]decreases reaction|increases activity 10780954
D010100 Oxygen SLC2A1 protein results in decreased susceptibility to Oxygen deficiencydecreases response to substance 10780954
C041786 palm oil palm oil results in increased expression of SLC2A1 mRNAincreases expression 18042831
D010424 Pentobarbital Pentobarbital inhibits the reaction [SLC2A1 protein results in increased uptake of 3-O-Methylglucose]decreases reaction|increases uptake 10590023
D010424 Pentobarbital Pentobarbital promotes the reaction [SLC2A1 gene polymorphism results in decreased uptake of 3-O-Methylglucose]decreases uptake|increases reaction 10590023
D010424 Pentobarbital Pentobarbital results in decreased activity of SLC2A1 proteindecreases activity 10590023
D010634 Phenobarbital Phenobarbital inhibits the reaction [SLC2A1 protein results in increased uptake of 3-O-Methylglucose]decreases reaction|increases uptake 10590023
D010634 Phenobarbital Phenobarbital promotes the reaction [SLC2A1 gene polymorphism results in decreased uptake of 3-O-Methylglucose]decreases uptake|increases reaction 10590023
D010634 Phenobarbital Phenobarbital results in decreased activity of SLC2A1 proteindecreases activity 10590023
D010656 Phenylephrine Phenylephrine results in increased expression of SLC2A1 mRNAincreases expression 15808844
D010693 Phloretin Phloretin inhibits the reaction [SLC2A1 protein affects the transport of Glucose]affects transport|decreases reaction 14642735
D010693 Phloretin Phloretin results in decreased activity of SLC2A1 proteindecreases activity 14642735
D010693 Phloretin Phloretin promotes the reaction [Cyclosporine results in increased expression of SLC2A1 mRNA]increases expression|increases reaction 12081571
D010693 Phloretin Phloretin promotes the reaction [Cyclosporine results in increased expression of SLC2A1 protein]increases expression|increases reaction 12081571
D010693 Phloretin Phloretin results in increased expression of SLC2A1 mRNAincreases expression 12081571
D010693 Phloretin Phloretin results in increased expression of SLC2A1 proteinincreases expression 12081571
D010743 Phospholipids 1-Butanol inhibits the reaction [Phospholipids results in increased localization of SLC2A1 protein]decreases reaction|increases localization 15956784
D010743 Phospholipids 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Phospholipids results in increased localization of SLC2A1 protein]decreases reaction|increases localization 15956784
D010743 Phospholipids Phospholipids results in increased localization of SLC2A1 proteinincreases localization 15956784
C006253 pirinixic acid pirinixic acid results in decreased expression of SLC2A1 mRNAdecreases expression 17426115
D011374 Progesterone [Progesterone co-treated with Estradiol] results in decreased expression of SLC2A1 proteinaffects cotreatment|decreases expression 15350188
D011374 Progesterone Progesterone results in increased expression of SLC2A1 proteinincreases expression 15350188
D011794 Quercetin Quercetin inhibits the reaction [SLC2A1 protein affects the transport of Glucose]affects transport|decreases reaction 14642735
D011794 Quercetin Quercetin results in decreased activity of SLC2A1 proteindecreases activity 14642735
D012402 Rotenone Rotenone inhibits the reaction [Oxygen deficiency results in increased expression of SLC2A1 mRNA]decreases reaction|increases expression 19091749
D012402 Rotenone SLC2A1 protein inhibits the reaction [Rotenone results in increased activity of MAPK8 protein]decreases reaction|increases activity 10780954
D012402 Rotenone SLC2A1 protein results in decreased susceptibility to Rotenonedecreases response to substance 10780954
C017947 sodium arsenite sodium arsenite results in decreased expression of SLC2A1 mRNAdecreases expression 12760830
C016104 sodium bichromate sodium bichromate results in decreased expression of SLC2A1 mRNAdecreases expression 12760830
D014284 Triiodothyronine Triiodothyronine results in increased expression of SLC2A1 mRNAincreases expression 15507505
D013629 Tamoxifen Tamoxifen inhibits the reaction [SLC2A1 protein affects the transport of Glucose]affects transport|decreases reaction 14642735
D013629 Tamoxifen Tamoxifen results in decreased activity of SLC2A1 proteindecreases activity 14642735
D013629 Tamoxifen Tamoxifen affects the expression of SLC2A1 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SLC2A1 mRNAaffects cotreatment|increases expression 19684285
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of SLC2A1 mRNAincreases expression 19684285
20106945
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin affects the expression of SLC2A1 mRNAaffects expression 17872374
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SLC2A1 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of SLC2A1 proteindecreases expression 17872374
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of SLC2A1 mRNAincreases expression 17035482
19684285
D013752 Tetracycline Tetracycline results in increased expression of SLC2A1 mRNAincreases expression 17522070
D014635 Valproic Acid Valproic Acid inhibits the reaction [SLC2A1 protein results in increased transport of Glucose]decreases reaction|increases transport 18455367
D014638 Vanadates Vanadates results in increased expression of SLC2A1 mRNAincreases expression 15297373
D014750 Vincristine SLC2A1 protein results in decreased susceptibility to Vincristinedecreases response to substance 17520257
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 3.7914745880
MESH:D000014 Abnormalities, Drug-Induced Ethanol 14.3618926900 17676605
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 14.366195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 14.3615322242 14514962 11752688
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 14.368875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.2619490988
MESH:D000138 Acidosis Ammonium Chloride 8.0218287403
MESH:D000138 Acidosis Ethanol 8.0211192467
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.1917505938
MESH:D058186 Acute Kidney Injury Ibuprofen 3.796375363
MESH:D055371 Acute Lung Injury nickel sulfate 11.4419131640 12718980 16100012 11954676
MESH:D055371 Acute Lung Injury Oxygen 11.4416759491
MESH:D055371 Acute Lung Injury pirinixic acid 11.4418653653
MESH:D000230 Adenocarcinoma arsenic trioxide 27.0819825857 11798837
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 27.0820127859 20464547
MESH:D000230 Adenocarcinoma daidzein 27.0811473722
MESH:D000230 Adenocarcinoma Doxorubicin 27.0817418594
MESH:D000230 Adenocarcinoma Estradiol 27.0811473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 27.0814692618
MESH:D000230 Adenocarcinoma Fluorouracil 27.0817638652
MESH:D000230 Adenocarcinoma Genistein 27.0811473722
MESH:D000230 Adenocarcinoma Ibuprofen 27.0810697514
MESH:D000230 Adenocarcinoma Vincristine 27.0819825857
MESH:D000236 Adenoma Benzo(a)pyrene 2.196695378
MESH:D018248 Adenoma, Liver Cell Phenobarbital 13.0317620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 13.0316434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 13.0316835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 3.9515276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.1517306315 16712894
MESH:D000419 Albuminuria Doxorubicin 3.8421441931
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.5615451040 15451039
MESH:D000544 Alzheimer Disease Aluminum 4.2910721010 17662457
MESH:D000544 Alzheimer Disease Ibuprofen 4.2918351690
MESH:D000550 Amblyopia Valproic Acid 4.4817688650
MESH:D000686 Amyloidosis Diethylstilbestrol 3.7715469931
MESH:D000707 Anaphylaxis Ibuprofen 4.529532969
MESH:D000740 Anemia Fluorouracil 6.5216511603 15504547 17963324
MESH:D000740 Anemia Tetrachlorodibenzodioxin 6.5211748828
MESH:D000743 Anemia, Hemolytic Quercetin 3.5717084956
MESH:D000799 Angioedema Acetaminophen 3.0910982225
MESH:D000853 Anophthalmos Ethanol 4.1015513904
MESH:D000860 Anoxia Oxygen 4.3220872349
MESH:D000881 Anthrax Ciprofloxacin 5.9620385868
MESH:D016736 Antiphospholipid Syndrome Ciprofloxacin 5.969485080
MESH:D001005 Anus Neoplasms Dacarbazine 5.5312170190
MESH:D001008 Anxiety Disorders Diazepam 16.2916284244 18313124
MESH:D001008 Anxiety Disorders Ethanol 16.2911141031
MESH:D001008 Anxiety Disorders Pentobarbital 16.2911141031 18313124
MESH:D001008 Anxiety Disorders Valproic Acid 16.2917497229
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.3519183758
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 3.4717460149
MESH:D001161 Arteriosclerosis Dietary Fats 7.5215238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 7.5211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.1715885639
MESH:D001249 Asthma epigallocatechin gallate 3.1216516891
MESH:D001259 Ataxia 1-Butanol 4.897820390
MESH:D001260 Ataxia Telangiectasia Quercetin 4.2415336622
MESH:D050197 Atherosclerosis Oxygen 3.3316391483
MESH:D001321 Autistic Disorder Acetaminophen 1.8818445737
MESH:D001321 Autistic Disorder Valproic Acid 1.8818316065 16609825 17157402 20603192 17507914 15238991 18558336 19232924 18985861 18177632 17688650 18940202 19460635 18396377 18775368
MESH:D001327 Autoimmune Diseases epigallocatechin gallate 8.6819761891
MESH:D001327 Autoimmune Diseases Quercetin 8.6819761891
MESH:D001424 Bacterial Infections Ciprofloxacin 5.1511505790
MESH:D001714 Bipolar Disorder Valproic Acid 2.6517594078 20046352
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 11.4216206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 11.4219483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 11.4212125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.0415340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 6.2915746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 6.298888407
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 3.9514601052
MESH:D001862 Bone Resorption bisphenol A 3.2011985600
MESH:D001919 Bradycardia Phenylephrine 3.8115306635
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.5817868700
MESH:D001930 Brain Injuries Progesterone 3.5415665606 15845082 15380490
MESH:D002545 Brain Ischemia Ibuprofen 4.1515837124
MESH:D001932 Brain Neoplasms Doxorubicin 3.1717150277
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 12.0520146248 17474063
MESH:D001943 Breast Neoplasms bisphenol A 12.0517123778
MESH:D001943 Breast Neoplasms Dacarbazine 12.0517983394
MESH:D001943 Breast Neoplasms Dietary Fats 12.0520435547
MESH:D001943 Breast Neoplasms Diethylstilbestrol 12.0515324884 17129689
MESH:D001943 Breast Neoplasms Doxorubicin 12.0515692762 16115903 16935488 15939500 15994142 17983394 15993339 15668708 18695136 18234424 16322301 18628466 18382427 11325840 16826403 15136595 17426702 16096432 15567936 19526202 16595493 17369602 15634643 16264153
MESH:D001943 Breast Neoplasms Estradiol 12.0512948864 16675129 17289903 19861407 14630087 17261762 18497071 17018787
MESH:D001943 Breast Neoplasms Fluorouracil 12.0516595493 15136595 16557594 18357371 16110121 18608205 19217205
MESH:D001943 Breast Neoplasms Genistein 12.0516541309 17200150 16873071
MESH:D001943 Breast Neoplasms kaempferol 12.0516756079
MESH:D001943 Breast Neoplasms Oxygen 12.0517263869
MESH:D001943 Breast Neoplasms Progesterone 12.0517614352 16175315 15562024
MESH:D001943 Breast Neoplasms Quercetin 12.0518628248
MESH:D001943 Breast Neoplasms Tamoxifen 12.0518629630 16873071 19155303 18984771 19059307 19487384 19115204 17049068 19103187 20859285 18855134 18425577 16202921 16818667 18351453 18815881 19142967 19244106 11161223 18821012 16273361 17440819 20135344 20390343 15668708 19288272 19289846 17261762 20065188 19189210 19189212 19410462 17242785 19084267 19200415 15565566 19011961 21138602 20005174 17893378 19221464 19066611 20544844 18997820 21152245
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 12.0520435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.6411589617
MESH:D002056 Burns Ethanol 3.9316374292
MESH:D002100 Cachexia Ibuprofen 4.7315141370
MESH:D002105 Cadmium Poisoning Quercetin 4.7916962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.7216111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.0616050911 16097048 16011737 18705752 15700767 3786805 15673190 16192424 10355542 16124888 15721981 16227642
MESH:D002276 Carcinoid Tumor Dacarbazine 16.9616051944
MESH:D002276 Carcinoid Tumor Doxorubicin 16.9616051944
MESH:D002276 Carcinoid Tumor Fluorouracil 16.9616051944
MESH:D002277 Carcinoma Fluorouracil 6.1817121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 6.1816835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 3.7819066611
MESH:D006528 Carcinoma, Hepatocellular marker/mechanism 8364915
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 30.483084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 30.4815073043 16217749 15553829 14691202 11135700
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 30.4818788625
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 30.4815948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 30.4816023760 18059187 17876044 16234567
MESH:D006528 Carcinoma, Hepatocellular Estradiol 30.4816924424
MESH:D006528 Carcinoma, Hepatocellular Ethanol 30.4815289165 15763234 18788625
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 30.4817971768 18930000 16799960 17088986 17045692 16332177
MESH:D006528 Carcinoma, Hepatocellular Genistein 30.4816924424
MESH:D006528 Carcinoma, Hepatocellular N-nitrosomorpholine 30.4819335982 19383236 1967229 15010824 10629087 8364915 9029167 2885971 11509945 1917145 9311599 9466558 16935385 15543204 1701930
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 30.4820007298 1701930 20935162 17173139 6705139
MESH:D006528 Carcinoma, Hepatocellular Quercetin 30.4819519916 12508355
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 30.4816507464 17306315 15276417
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 30.4816924424
MESH:D002278 Carcinoma in Situ bisphenol A 4.2517123778
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.2317234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.1219014326
MESH:D002292 Carcinoma, Renal Cell marker/mechanism 7921415
MESH:D002292 Carcinoma, Renal Cell Dacarbazine 15.9116201981
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 15.911485588 16201981
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 15.9118695887
MESH:D002292 Carcinoma, Renal Cell N-nitrosomorpholine 15.917921415 1429202
MESH:D002292 Carcinoma, Renal Cell Vincristine 15.9116201981
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.4612490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 11.2420419170
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 11.246189445
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 11.2416757204 16280240 17066447 18986760
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 11.2418572023
MESH:D002294 Carcinoma, Squamous Cell Vincristine 11.246189445
MESH:D002295 Carcinoma, Transitional Cell Amiloride 12.4514644129
MESH:D002295 Carcinoma, Transitional Cell Ciprofloxacin 12.4515028437 10741713
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 12.4517572228
MESH:D006332 Cardiomegaly Ethanol 12.5219332462
MESH:D006332 Cardiomegaly Phenylephrine 12.5217124262 11179087 15728586 17287366 11754973 16170337
MESH:D006332 Cardiomegaly Quercetin 12.5219794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 12.5216120746 18850075 18670907
MESH:D009202 Cardiomyopathies Doxorubicin 3.0117382496 16269455 16455267 17351982 16731534 17519947 17924179 16612575 15792986 17308081 17928571 17329180 15811867 15476868 16651473 16364871 17974986 18627295 16109756 17007740 16952015 17131338 16278810 15505089 16242529
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.6316243910 17334414
MESH:D002318 Cardiovascular Diseases daidzein 9.3216332659
MESH:D002318 Cardiovascular Diseases Genistein 9.3216332659
MESH:D002318 Cardiovascular Diseases kaempferol 9.3216756079
MESH:D002386 Cataract Acetaminophen 6.1610977129
MESH:D002386 Cataract Adenosine Triphosphate 6.1615003327
MESH:D002471 Cell Transformation, Neoplastic marker/mechanism 11953883
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 8.0312371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 8.0318566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 8.0319524636 20056578
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.534080065
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.3820734317
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.5316835633
MESH:D002761 Cholangitis 1-Naphthylisothiocyanate 5.4512912871
MESH:D002779 Cholestasis 1-Naphthylisothiocyanate 14.5612927374 15913567 15500046 19486331 18590720 18164287 16629650 7624871
MESH:D002779 Cholestasis Cyclosporine 14.5619486331
MESH:D002779 Cholestasis Ethinyl Estradiol 14.5617333356 17681005 16919318 15861022 17110522 16105132 11677210
MESH:D002779 Cholestasis pirinixic acid 14.5619176532
MESH:D002780 Cholestasis, Intrahepatic 1-Naphthylisothiocyanate 5.1010220858 19407337
MESH:D002971 Cleft Lip Ethanol 3.1415513904
MESH:D002972 Cleft Palate Diazepam 7.863629520
MESH:D002972 Cleft Palate Ethanol 7.8615513904
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 7.8615668235 15340226 12621046 8697196 16354765
MESH:D003092 Colitis Amiloride 4.3912065299
MESH:D003110 Colonic Neoplasms marker/mechanism 11953883
MESH:D003110 Colonic Neoplasms Fluorouracil 4.7017725105 17018589 16510598 17169374 15001691 17287894 17016597 16340194 17172411 18772588
MESH:D003110 Colonic Neoplasms Genistein 4.7017182828
MESH:D003110 Colonic Neoplasms Quercetin 4.7015741050 19056647 11134977 17191121 19440933 17148506 16640504
MESH:D015179 Colorectal Neoplasms arsenic trioxide 5.2920501625
MESH:D015179 Colorectal Neoplasms Dacarbazine 5.2915273666
MESH:D015179 Colorectal Neoplasms Doxorubicin 5.2918259882 18802399
MESH:D015179 Colorectal Neoplasms Fluorouracil 5.2918949393 16391804 17094418 17401013 17016601 17454858 17255274 20501625 14970324 17695437 18288408 15148649 17594712 16331619 15289873 18802399 16303861 16524972 18448328 18383874 16282729 18509181
MESH:D015179 Colorectal Neoplasms Quercetin 5.2918852136 18095365
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.4317141729 14669216
MESH:D023903 Coronary Restenosis arsenic trioxide 3.4812609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 4.3910525206
MESH:D019465 Craniofacial Abnormalities Ethanol 4.3911198716 15513904 15451039 15451040 10194807 11873399 19302082
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 4.3910048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Valproic Acid 4.3916575769 17688650 8888407
MESH:D003456 Cryptorchidism Diethylstilbestrol 3.8512952375 16002989
MESH:D003550 Cystic Fibrosis Ciprofloxacin 7.6819747007
MESH:D003550 Cystic Fibrosis Ofloxacin 7.6819747007
MESH:D007644 Darier Disease Fluorouracil 4.0516733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.4115213294
MESH:D003711 Demyelinating Diseases Tamoxifen 3.6419031437
MESH:D017449 Dermatitis, Allergic Contact cobaltous chloride 5.2911298694 15059100 16823706
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 5.2916780908 16823706 11298694
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.0318249437
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.1219496084
MESH:D003924 Diabetes Mellitus, Type 2 daidzein 8.2116647724
MESH:D003924 Diabetes Mellitus, Type 2 epigallocatechin gallate 8.2116988119
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 8.2116647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 8.2117107852
MESH:D003928 Diabetic Nephropathies Estradiol 6.7319279558
MESH:D003928 Diabetic Nephropathies Tamoxifen 6.7319279558
MESH:D003929 Diabetic Neuropathies Progesterone 3.7717187935
MESH:D004342 Drug Hypersensitivity Dacarbazine 4.4616508601
MESH:D056486 Drug-Induced Liver Injury 1-Naphthylisothiocyanate 19.9720133375 17522070 7624871 18289764
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 19.9716109766 10915739 11461765 19739265 16781746 12153990 19923254 18713872 19370779 11739529 17522070 11743745 12705907 17906064 19085960 10774834 12958197 19164858 16081117 15619225 11421492 19416960 15968718 12540782 16485898 11287661 17562736 11529661 18071297 12594235 16227642 14550746 14725611 10663392 16177239 12392966 2444490 19420014 14986274 16393943 11834606
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 19.973786805 2869522 3732212 6884620 15998439 19085960 17522070 10915739 11566570 15968718 9327722 16177239 7440962 21278145 7120509 16227642 4309450 10092053 6623471 15027814 19336974 7179309
MESH:D056486 Drug-Induced Liver Injury Chloroform 19.973104120 17522070 6884620 6623471 7120509 2862719 3732212 7440962
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 19.9717416283
MESH:D056486 Drug-Induced Liver Injury Ethanol 19.9711566570
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 19.9720420201
MESH:D056486 Drug-Induced Liver Injury Tetracycline 19.9717522070
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 19.971733752 19641884
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.3419426721
MESH:D004362 Drug Toxicity Doxorubicin 6.2018602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 6.2011462148
MESH:D004374 Ductus Arteriosus, Patent Ibuprofen 4.8718446180 18450898 16133044
MESH:D050171 Dyslipidemias Dietary Fats 2.8918367378
MESH:D004417 Dyspnea Oxygen 4.0920016425
MESH:D004421 Dystonia marker/mechanism
MESH:D004421 Dystonia Diazepam 13.931851702
MESH:D004421 Dystonia Phenobarbital 13.931851702
MESH:D004421 Dystonia Valproic Acid 13.931851702
MESH:D004487 Edema pirinixic acid 4.3912083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 4.3912711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.1518230668 15322242 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 11.2712538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 11.2717692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 11.2719031437
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 9.4416402032
MESH:D004714 Endometrial Hyperplasia Genistein 9.4416402032
MESH:D016889 Endometrial Neoplasms daidzein 22.3411473722
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 22.3415700306 16804899
MESH:D016889 Endometrial Neoplasms Doxorubicin 22.3417359293
MESH:D016889 Endometrial Neoplasms Estradiol 22.3418566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Genistein 22.3411473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 22.3419155303 17893378 16202921 20544844
MESH:D004715 Endometriosis Ibuprofen 11.6015652904
MESH:D004715 Endometriosis Progesterone 11.6016134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 11.6010568697 9294722
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.4018037988
MESH:D019446 Endotoxemia Ibuprofen 4.2311545620
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 8.403659116
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 8.403659116 17275665
MESH:D004828 Epilepsies, Partial Barbiturates 18.1011558140
MESH:D004828 Epilepsies, Partial Diazepam 18.103922381
MESH:D004828 Epilepsies, Partial Phenobarbital 18.103922381 11558140
MESH:D004828 Epilepsies, Partial Valproic Acid 18.103922381 16628512
MESH:D004827 Epilepsy Diazepam 8.67821787
MESH:D004827 Epilepsy Phenobarbital 8.6720417680
MESH:D004827 Epilepsy Valproic Acid 8.6718234410 20417680
MESH:D004832 Epilepsy, Absence Diazepam 11.426426943 6401628
MESH:D004832 Epilepsy, Absence Phenobarbital 11.426401628
MESH:D004832 Epilepsy, Absence Valproic Acid 11.426426943 7562514 6254150
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 8.907750514
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 8.907750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 8.033659116
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 8.033659116
MESH:D007172 Erectile Dysfunction daidzein 4.3114972507
MESH:D004938 Esophageal Neoplasms arsenic trioxide 8.2212903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 8.2216530937
MESH:D004938 Esophageal Neoplasms Ethanol 8.2216704527
MESH:D004938 Esophageal Neoplasms Fluorouracil 8.2216785472 16337965 16481741 15173087 17638652
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.4311564622
MESH:D005234 Fatty Liver arsenic trioxide 41.8915073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 41.8912795759 19224547 12631006 61145 15959796 17595544 16045604 16239168
MESH:D005234 Fatty Liver Cyclosporine 41.8919224547
MESH:D005234 Fatty Liver Dietary Fats 41.8917967931 19551842 19004024 18296743
MESH:D005234 Fatty Liver Ethanol 41.8919236843 18620774 16409862
MESH:D005234 Fatty Liver Ethinyl Estradiol 41.8915345470
MESH:D005234 Fatty Liver pirinixic acid 41.8919236843 20131406
MESH:D005234 Fatty Liver Tamoxifen 41.8919224547 14986274
MESH:D005234 Fatty Liver Tetracycline 41.8916917069 19224547
MESH:D005234 Fatty Liver Valproic Acid 41.8919224547 14986274
MESH:D005235 Fatty Liver, Alcoholic Ethanol 4.9117920746
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 6.5516002989 16611131 16534752 16513791 15751030
MESH:D052776 Female Urogenital Diseases Tamoxifen 6.5516709447
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.5615513904 16946407 15451040 10194807
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.7411858732
MESH:D005315 Fetal Diseases Valproic Acid 4.1316575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 3.438888407 18558336
MESH:D005334 Fever Ibuprofen 3.9416997862
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 3.7914745880
MESH:D018222 Fibromatosis, Aggressive Dacarbazine 15.3919069698
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 15.3919069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 15.3919069698
MESH:D005355 Fibrosis Carbon Tetrachloride 20.1618705752
MESH:D005355 Fibrosis Cyclosporine 20.1612168785 12639820
MESH:D005355 Fibrosis Dietary Fats 20.1618296743
MESH:D005355 Fibrosis Quercetin 20.1619474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 20.1620067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.5616904648
MESH:D005739 Gas Poisoning Oxygen 4.4720016425
MESH:D005756 Gastritis Acetaminophen 8.6316983495
MESH:D005756 Gastritis Ethanol 8.6315046732
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 10.3616452187
MESH:D005833 Genital Neoplasms, Female sodium arsenite 10.3616452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.488708960
MESH:D005909 Glioblastoma Dacarbazine 16.7812592361 12853885
MESH:D005909 Glioblastoma Doxorubicin 16.7817150277
MESH:D005909 Glioblastoma Genistein 16.7816598420
MESH:D005909 Glioblastoma myricetin 16.7819804834
MESH:D005909 Glioblastoma Quercetin 16.7819804834
MESH:D005910 Glioma Fluorouracil 4.9816145905
MESH:D005910 Glioma Quercetin 4.9817643826
OMIM:606777 GLUT1 DEFICIENCY SYNDROME 1 marker/mechanism 17489814
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.8410696789
MESH:D006130 Growth Disorders Amiloride 4.2419703807
MESH:D006258 Head and Neck Neoplasms Doxorubicin 6.1315692506
MESH:D006258 Head and Neck Neoplasms Fluorouracil 6.1315162350 18337622 15102660
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 4.9520471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 4.9510048152 11294989
MESH:D006331 Heart Diseases Ciprofloxacin 6.4511505790
MESH:D006331 Heart Diseases Doxorubicin 6.4514766674 16244371 16879835 16330681 16495754 16244372 16707910 17875725 12587719 16144979 17888722 18674790 18006777
MESH:D006333 Heart Failure Doxorubicin 5.3817481944
MESH:D006333 Heart Failure pirinixic acid 5.3820558911
MESH:D016481 Helicobacter Infections Ciprofloxacin 4.7917643012
MESH:D006394 Hemangiosarcoma Doxorubicin 3.2415692506
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.6815720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.6711000095
MESH:D006505 Hepatitis 1-Naphthylisothiocyanate 7.3318590720
MESH:D006505 Hepatitis Carbon Tetrachloride 7.3319110552 19900420
MESH:D006529 Hepatomegaly Phenobarbital 10.2416109766
MESH:D006529 Hepatomegaly pirinixic acid 10.2418467677 19176532 16221962 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 10.2412621046 15340226 16120746
MESH:D006558 Herpes Genitalis Estradiol 4.2815709030
MESH:D006689 Hodgkin Disease Dacarbazine 12.4718501091 16170182
MESH:D006689 Hodgkin Disease Doxorubicin 12.4715147373 18501091 17606976
MESH:D006689 Hodgkin Disease sodium arsenite 12.4712676792
MESH:D006689 Hodgkin Disease Vincristine 12.4716794504 15147373 17606976 16135485
MESH:D019584 Hot Flashes Estradiol 3.0117088409
MESH:D006849 Hydrocephalus Valproic Acid 4.1317688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.2916959395 15340226 8697196 18606429 16354765
MESH:D006930 Hyperalgesia Acetaminophen 5.8216870215
MESH:D006930 Hyperalgesia Ethanol 5.8218783367
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.7916899240
MESH:D006937 Hypercholesterolemia Dietary Fats 2.9321332399
MESH:D006943 Hyperglycemia kaempferol 12.0418262572
MESH:D006943 Hyperglycemia pirinixic acid 12.0420558911
MESH:D006943 Hyperglycemia Quercetin 12.0418262572 11834736
MESH:D006949 Hyperlipidemias Dietary Fats 2.9421332399
MESH:D006965 Hyperplasia Diethylstilbestrol 3.7212960047 14722030
MESH:D006973 Hypertension Amiloride 16.0118524855 15174897 19344079
MESH:D006973 Hypertension Cyclosporine 16.0110903974
MESH:D006973 Hypertension daidzein 16.0117169123
MESH:D006973 Hypertension Phenylephrine 16.0112717712 8949925
MESH:D006973 Hypertension Quercetin 16.0118356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 16.0118850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.3715338365
MESH:D006984 Hypertrophy Ibuprofen 8.6916672835
MESH:D006984 Hypertrophy Phenylephrine 8.6918502941 12791704
MESH:D020514 Hypokalemic Periodic Paralysis Amiloride 5.1119822448
MESH:D007021 Hypospadias Diethylstilbestrol 8.8416002989
MESH:D007021 Hypospadias Ethinyl Estradiol 8.8416569931 16945680
MESH:D007235 Infant, Premature, Diseases Ibuprofen 5.0816133044
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 3.6815869954
MESH:D007246 Infertility Diethylstilbestrol 3.6515036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.7812013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 4.8917937319
MESH:D007248 Infertility, Male sodium arsenite 4.8912646999 15346721
MESH:D007249 Inflammation Aluminum 17.4516052892
MESH:D007249 Inflammation Amiloride 17.4517237260
MESH:D007249 Inflammation Dietary Fats 17.4520412841
MESH:D007249 Inflammation Ibuprofen 17.453291741
MESH:D007249 Inflammation Progesterone 17.4515869954
MESH:D007249 Inflammation Tamoxifen 17.4519457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 17.4512878042 12200463
MESH:D007251 Influenza, Human Quercetin 3.7616624496
MESH:D007333 Insulin Resistance bisphenol A 13.3316393666
MESH:D007333 Insulin Resistance Dietary Fats 13.3311836018 18457598
MESH:D007333 Insulin Resistance Estradiol 13.3316393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 13.3316306350
MESH:D007569 Jaw Abnormalities Ethanol 7.8915513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 7.8916580747
MESH:D007627 Keloid Quercetin 4.2317086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.6915604871
MESH:D007674 Kidney Diseases Acetaminophen 21.5415629191 12587719
MESH:D007674 Kidney Diseases Cadmium Chloride 21.5416962696
MESH:D007674 Kidney Diseases Cyclosporine 21.548314463 18776723 10903974
MESH:D007674 Kidney Diseases Doxorubicin 21.5416775033 15699352 15369732
MESH:D007674 Kidney Diseases Estradiol 21.5415618244
MESH:D007674 Kidney Diseases Quercetin 21.5416962696
MESH:D007674 Kidney Diseases sodium arsenite 21.5420008137
MESH:D007676 Kidney Failure, Chronic Doxorubicin 3.4916707910
MESH:D007680 Kidney Neoplasms Cyclosporine 16.8612371664
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 16.8615003126 14681315 16762066
MESH:D007680 Kidney Neoplasms Estradiol 16.8615610895
MESH:D007680 Kidney Neoplasms Fluorouracil 16.8616985049
MESH:D007680 Kidney Neoplasms Tamoxifen 16.8618625569
MESH:D007859 Learning Disorders Diethylstilbestrol 7.4017184923
MESH:D007859 Learning Disorders Ethanol 7.4015451040
MESH:D007938 Leukemia 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 15.1612970779
MESH:D007938 Leukemia arsenic trioxide 15.1615070760
MESH:D007938 Leukemia Genistein 15.1617468513 18980019
MESH:D007938 Leukemia kaempferol 15.1617468513
MESH:D007938 Leukemia Quercetin 15.1617468513
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.4016085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.1317077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.5716972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 2.8614633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.0919077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.2616467208 16968895 19850784 20471514 17050201
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 3.2616294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 2.6917217047 16112521 15622746 15748426 17869043 11468182 15213294 19642359 11161223 19075265 17649720 17107899 16891316 12712474 16966277 9834237 16330433 12018890 12679006 15336539 16823087 17712046 19225113 16331271 19035177
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.6516882451
MESH:D007970 Leukopenia Ciprofloxacin 5.0617846019
MESH:D056929 Liddle Syndrome Amiloride 5.2519344079
MESH:D017880 Limb Deformities, Congenital Ethanol 3.2617676605
MESH:D008064 Lipidoses Tamoxifen 2.6015342952 17567588
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 11.9611408273 16943688 16239168 21278145 11903743 17157831 17334410 17174718 16221502
MESH:D008103 Liver Cirrhosis Dietary Fats 11.9618296743
MESH:D008103 Liver Cirrhosis Ethanol 11.9615289165
MESH:D008103 Liver Cirrhosis Phenobarbital 11.9621047994
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.3618295389
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 17.2712445418 16116963 14620537 15057751 17761835 18395095 18395914 14716833 15730626 17565644 15925388 18317297 12649538 16033810 12632514 14724832 18339082 17976157 18006644 17721639 18376398 17944888 12546737 17900296 17631135 11481614 15673190 18263696 17481882 18166357 15123356 16097048 17869086 14716496 18472332 15893842 12667390 15650968 18418968 16011737 17557913 18705752 17640975 10355542 12741479 15959796 12632512 20821823 16027843 18279442 17922224 12609069 15818738 18277467 16136751 18205269 17805973 18420326 16638106 18481824 17698563 16015684 18054572 12666154 17714472 17823541 17708605 15052691 15338365 13678700 18412020 17766677 12898905 18429990 15370692 16248980 15931870 15362042 18156304 14512876 12445421 15876570 12958196 17525996 18187930 15996030 16192424 18210741 14748882 12586293 18251166 12389079 18472094
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 17.2716595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental epigallocatechin gallate 17.2717481882
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 17.2714716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 17.2718166357
MESH:D008106 Liver Cirrhosis, Experimental Genistein 17.2717823541
MESH:D008106 Liver Cirrhosis, Experimental naringenin 17.2714709902
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 17.2715474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 17.2712741479
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 17.2718564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 17.2712878042
MESH:D008107 Liver Diseases 1-Naphthylisothiocyanate 9.7017184895
MESH:D008107 Liver Diseases Acetaminophen 9.7012587719 19460945 19784758 16611625 16610002 12969438 11587558 19014921
MESH:D008107 Liver Diseases Carbon Tetrachloride 9.7015830285 16246199 15720792 17285989 16964402
MESH:D008107 Liver Diseases naringenin 9.7016945181
MESH:D008107 Liver Diseases Phenobarbital 9.7019363144
MESH:D008108 Liver Diseases, Alcoholic Ethanol 3.9317347304 17207112
MESH:D017093 Liver Failure Carbon Tetrachloride 3.4415123358
MESH:D017114 Liver Failure, Acute Acetaminophen 7.2417185352 16871587
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 7.2416899240 14706259
MESH:D008113 Liver Neoplasms arsenic trioxide 30.1714682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 30.1721137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 30.1719294768
MESH:D008113 Liver Neoplasms Diethylstilbestrol 30.1715890375 16712894
MESH:D008113 Liver Neoplasms Fluorouracil 30.1715113037 17045692 18383874 16603448
MESH:D008113 Liver Neoplasms Phenobarbital 30.1719812893 15975961 21047994 8742319 19482888 19073162
MESH:D008113 Liver Neoplasms pirinixic acid 30.1720007298 16377806 15890375
MESH:D008113 Liver Neoplasms Quercetin 30.1718980244
MESH:D008113 Liver Neoplasms sodium arsenite 30.1715276417 16712894
MESH:D008113 Liver Neoplasms Tamoxifen 30.1716684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 30.1716984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 16.8320377131
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 16.8312014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 16.8317085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 16.8317172636 6150874 1399818 18308698 2563599
MESH:D008114 Liver Neoplasms, Experimental Quercetin 16.8319519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 16.8312151625
MESH:D008133 Long QT Syndrome arsenic trioxide 2.7715213294
MESH:D008171 Lung Diseases Aluminum 6.2016052892
MESH:D008171 Lung Diseases sodium arsenite 6.2019095001
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 3.5117228818
MESH:D055370 Lung Injury Ciprofloxacin 7.5118197910
MESH:D055370 Lung Injury Oxygen 7.5118339021
MESH:D008175 Lung Neoplasms arsenic trioxide 14.6719825857 11798837
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 14.6720464547 18569708 17053015 18520028 6695378 20064080 20135361 20869020 18816296
MESH:D008175 Lung Neoplasms Ciprofloxacin 14.6720211752
MESH:D008175 Lung Neoplasms Doxorubicin 14.6717418594 6189445
MESH:D008175 Lung Neoplasms Fluorouracil 14.6715246190
MESH:D008175 Lung Neoplasms Quercetin 14.6716280456
MESH:D008175 Lung Neoplasms sodium arsenite 14.6717077188 16712894 15276417 19931552 17306315
MESH:D008175 Lung Neoplasms Tamoxifen 14.6718625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 14.6719555203 11884234
MESH:D008175 Lung Neoplasms Vincristine 14.676189445 19825857
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.0515086387
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.4115166399
MESH:D008223 Lymphoma Diethylstilbestrol 5.8915700306
MESH:D008223 Lymphoma Doxorubicin 5.8916098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.1817654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 3.8415621674
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 4.7616002989
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.0319428831
MESH:D008325 Mammary Neoplasms, Experimental Corticosterone 20.6212807724
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 20.6215458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 20.6211408345 16891317 11807958 17203775
MESH:D008325 Mammary Neoplasms, Experimental Genistein 20.6214578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Ibuprofen 20.6210697514
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 20.6211408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 20.6219196723 19196722 11731420 16827153 14580682
MESH:D020149 Manganese Poisoning Estradiol 10.1519453300
MESH:D020149 Manganese Poisoning Tamoxifen 10.1519453300
MESH:D008545 Melanoma Dacarbazine 9.9318281670 12025231 16225601 16034308 18176117 12556972 18332650 18089842 17023156 18505091 12883367 17761969 16248763 15917704 12202904 12535206 17709802 16939954 17576460 15577323 16966688 15020614 10623706 16809738 18445842 17973783 15176220 16760174 17623835 17334785 11712820 15522559 16273263 11254118 17239242 17562445 12417787 16098027 17508024 17119449 12439608 15577320 12640292 16508601 16928243 11135225 12393984 11746506
MESH:D008545 Melanoma Doxorubicin 9.9316827129
MESH:D008545 Melanoma epigallocatechin gallate 9.9311746506 17992120
MESH:D008545 Melanoma Glucose 9.9314993021
MESH:D008545 Melanoma sodium arsenite 9.9316487513 19082730
MESH:D008545 Melanoma Tamoxifen 9.9312393984 19393235
MESH:D018328 Melanoma, Amelanotic Dacarbazine 15.5515990972
MESH:D018328 Melanoma, Amelanotic Tamoxifen 15.5515990972
MESH:D018328 Melanoma, Amelanotic Vincristine 15.5515990972
MESH:D008546 Melanoma, Experimental Acetaminophen 2.8519513568
MESH:D008569 Memory Disorders Ethanol 3.4915451040 18411066
MESH:D008654 Mesothelioma Doxorubicin 2.7117638057
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.0316801185
MESH:D008881 Migraine Disorders Valproic Acid 2.6418803445 18765137
MESH:D028361 Mitochondrial Diseases Doxorubicin 3.8315792986
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 6.5716381670
MESH:D009062 Mouth Neoplasms Fluorouracil 6.5716757204 18986760
MESH:D052016 Mucositis Doxorubicin 4.0517415656
MESH:D009101 Multiple Myeloma arsenic trioxide 2.5615949261 19417148 14977855 19549372 11468182
MESH:D020528 Multiple Sclerosis, Chronic Progressive Aluminum 5.6217086897
MESH:D020529 Multiple Sclerosis, Relapsing-Remitting Aluminum 5.6217086897
MESH:D009134 Muscular Atrophy, Spinal epigallocatechin gallate 4.7517962980
MESH:D009135 Muscular Diseases pirinixic acid 2.7916239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.368888407
MESH:D009164 Mycobacterium Infections Ciprofloxacin 9.3810063276
MESH:D009164 Mycobacterium Infections Ofloxacin 9.3818474467
MESH:D009182 Mycosis Fungoides arsenic trioxide 3.9218349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 9.7516105982 16882451
MESH:D009190 Myelodysplastic Syndromes Ciprofloxacin 9.759809623
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 9.7517596541
MESH:D009203 Myocardial Infarction Doxorubicin 13.8919429709 15857846
MESH:D009203 Myocardial Infarction Genistein 13.8917141266
MESH:D009203 Myocardial Infarction pirinixic acid 13.8919151258
MESH:D009203 Myocardial Infarction Quercetin 13.8919595682
MESH:D009203 Myocardial Infarction Vincristine 13.8917284715
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.4112213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 15.4616810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 15.4617141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 15.4616411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 15.4619207477
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 3.7417484760
MESH:D009207 Myoclonus Chloral Hydrate 6.078041377
MESH:D016870 Neisseriaceae Infections Ciprofloxacin 5.6120378725
MESH:D009361 Neoplasm Invasiveness Amiloride 8.3314644129
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 8.3316624393
MESH:D009362 Neoplasm Metastasis Doxorubicin 4.6618259882
MESH:D009362 Neoplasm Metastasis Tamoxifen 4.6619393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.2219410462
MESH:D009369 Neoplasms Benzo(a)pyrene 17.4811141357
MESH:D009369 Neoplasms Diethylstilbestrol 17.4815313581
MESH:D009369 Neoplasms Fluorouracil 17.4816928823 18239605 18600527
MESH:D009369 Neoplasms naringenin 17.4815185748
MESH:D009369 Neoplasms pirinixic acid 17.4817405874
MESH:D009369 Neoplasms Quercetin 17.4815185748
MESH:D009369 Neoplasms sodium arsenite 17.4811559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 2.9620056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.2519200415 19196722 19189210
MESH:D009389 Neovascularization, Pathologic Estradiol 3.0017289903
MESH:D009395 Nephritis, Interstitial Ibuprofen 8.536375363
MESH:D009395 Nephritis, Interstitial Tetracycline 8.539884423
MESH:D009401 Nephrosis Doxorubicin 4.0416899518 16636307
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.6917954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 7.1819348381 18481113
MESH:D009404 Nephrotic Syndrome Doxorubicin 7.1816889571 15640375
MESH:D009410 Nerve Degeneration Ibuprofen 6.9310961664
MESH:D009410 Nerve Degeneration Rotenone 6.9315790535 17356569 18619942
MESH:D009421 Nervous System Malformations bisphenol A 23.3411399458 16427766
MESH:D009421 Nervous System Malformations Diethylstilbestrol 23.3411399458
MESH:D009421 Nervous System Malformations Estradiol 23.3416427766 11399458
MESH:D009421 Nervous System Malformations Genistein 23.3416427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 23.3414600291
MESH:D009436 Neural Tube Defects arsenic trioxide 9.1210525206
MESH:D009436 Neural Tube Defects sodium arsenite 9.1212854658
MESH:D009436 Neural Tube Defects Valproic Acid 9.128888407 16359493
MESH:D009447 Neuroblastoma Doxorubicin 2.8315555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.2618514411
MESH:D017599 Neuroectodermal Tumors Vincristine 4.9712837982
MESH:D020078 Neurogenic Inflammation Quercetin 3.6717929310
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 2.9016436463
MESH:D009503 Neutropenia Ciprofloxacin 4.4817846019
MESH:D009765 Obesity Dietary Fats 3.5918457598 20132043 16723640 18674790 21332399 19632207 11836018 17217161 20518802
MESH:D009765 Obesity pirinixic acid 3.5920558911
MESH:D010003 Osteoarthritis Ibuprofen 3.647009135
MESH:D010018 Osteomalacia Phenobarbital 3.6317016548
MESH:D010024 Osteoporosis Genistein 6.0119401787
MESH:D010024 Osteoporosis kaempferol 6.0116756079
MESH:D015663 Osteoporosis, Postmenopausal Genistein 7.8616169203
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 7.8619495926
MESH:D012516 Osteosarcoma Doxorubicin 3.5015930896
MESH:D010049 Ovarian Diseases bisphenol A 4.2511985600
MESH:D010051 Ovarian Neoplasms 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 18.1916211241
MESH:D010051 Ovarian Neoplasms arsenic trioxide 18.1916624393 12452020 19769630
MESH:D010051 Ovarian Neoplasms Estradiol 18.1919401270
MESH:D010051 Ovarian Neoplasms Genistein 18.1919005980
MESH:D010051 Ovarian Neoplasms Progesterone 18.1916525653 17393432
MESH:D010051 Ovarian Neoplasms Quercetin 18.1919005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 18.1917306315 15276417
MESH:D010146 Pain Acetaminophen 4.9716870215
MESH:D010146 Pain Ibuprofen 4.973291741
MESH:D010149 Pain, Postoperative Ibuprofen 4.3916678543
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 19.6615580305
MESH:D010190 Pancreatic Neoplasms Dacarbazine 19.6611583197
MESH:D010190 Pancreatic Neoplasms Ethanol 19.6612384795
MESH:D010190 Pancreatic Neoplasms Fluorouracil 19.6616929163 19003803 16500647 15113037
MESH:D010190 Pancreatic Neoplasms Ibuprofen 19.6612384795
MESH:D010190 Pancreatic Neoplasms Phenobarbital 19.6616965848
MESH:D010190 Pancreatic Neoplasms Quercetin 19.6616965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.0011578682
MESH:D010235 Paraganglioma arsenic trioxide 3.4719927285
MESH:D010300 Parkinson Disease Rotenone 2.6611535288 19232380 11445065 16412576 16140633 18619942 15451049 18191903 19114014
MESH:D020734 Parkinsonian Disorders Rotenone 3.4318197244 15927086 15574749 15795934
MESH:D010382 Peliosis Hepatis 1-Naphthylisothiocyanate 11.2920133375
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 11.2912520081
MESH:D010391 Pemphigoid, Bullous Tetracycline 4.6811026799
MESH:D003557 Phyllodes Tumor Dacarbazine 11.8617983394
MESH:D003557 Phyllodes Tumor Doxorubicin 11.8617983394
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.4114722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 3.9515687265 16977796
MESH:D010997 Pleural Neoplasms Doxorubicin 4.4017638057
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.8518163543
MESH:D011230 Precancerous Conditions Cyclosporine 11.6612371664
MESH:D011230 Precancerous Conditions Phenobarbital 11.662563599
MESH:D011230 Precancerous Conditions Quercetin 11.6619056647
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Vincristine 4.1621297632
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 17.2410548101
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 17.2417184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 17.2411118676 11399792 11896295 11222880
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 17.2420603192
MESH:D017096 Prion Diseases Tetracycline 4.6710903871
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 8.3220887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 8.3220887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 4.2319131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 4.2317292933
MESH:D011471 Prostatic Neoplasms bisphenol A 4.2316740699
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 4.2317136230 15046698 15846301
MESH:D011471 Prostatic Neoplasms Doxorubicin 4.2316888761 16729912 18437689 15897917 16868541 15749863
MESH:D011471 Prostatic Neoplasms Estradiol 4.2316740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 4.2318626508 19082440
MESH:D011471 Prostatic Neoplasms Genistein 4.2316925846 15378649 15256057
MESH:D011471 Prostatic Neoplasms Ibuprofen 4.2317409433
MESH:D011471 Prostatic Neoplasms Quercetin 4.2317292933 14715546
MESH:D011471 Prostatic Neoplasms sodium arsenite 4.2316039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 4.2315067354
MESH:D011507 Proteinuria Ibuprofen 3.956375363
MESH:D011537 Pruritus Ethinyl Estradiol 2.5815861022 16919318
MESH:D019310 Pseudolymphoma Phenobarbital 9.6912752131
MESH:D019310 Pseudolymphoma Valproic Acid 9.6912752131 11422049
MESH:D011565 Psoriasis Cyclosporine 1.9116882103
MESH:D011629 Puberty, Precocious bisphenol A 4.0510548101
MESH:D012003 Rectal Fistula Ciprofloxacin 5.6118371140
MESH:D012004 Rectal Neoplasms Fluorouracil 3.3718286688 16160472 15538739 18722050
MESH:D012021 Reflex, Abnormal Pentobarbital 5.2810930210
MESH:D051437 Renal Insufficiency Doxorubicin 3.5017922066
MESH:D015427 Reperfusion Injury pirinixic acid 1.9719058328
MESH:D012128 Respiratory Distress Syndrome, Adult Oxygen 3.8317627322 18339021
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.1318990726
MESH:D012208 Rhabdomyosarcoma Valproic Acid 3.4919155313
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.5318045962
MESH:D012509 Sarcoma Dacarbazine 7.8517898927 18313854
MESH:D012509 Sarcoma Doxorubicin 7.8518313854 17710206 16767912 17203757 15675481 15625365
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 7.9416646077
MESH:D012512 Sarcoma, Ewing's Doxorubicin 7.9416326096 14601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.0517846226
MESH:D012554 Schistosomiasis japonica Quercetin 4.7916862918
MESH:D012559 Schizophrenia Valproic Acid 1.9519110320 15737665
MESH:D012640 Seizures Diazepam 12.9615946322 9754883 10087439
MESH:D012640 Seizures Ethanol 12.969754883
MESH:D012640 Seizures Pentobarbital 12.969754883 10087439
MESH:D012640 Seizures Phenobarbital 12.963137016 16876388 4039156 11442880
MESH:D012640 Seizures Valproic Acid 12.963137016 14763951 11044598 16876388 15475178 17978042 1511512 11738929
MESH:D003294 Seizures, Febrile Phenobarbital 4.086407741
MESH:D012852 Sinusitis Phenylephrine 3.977327846
MESH:D012871 Skin Diseases monomethylarsonic acid 3.7721378128
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 13.5519755658 10029692
MESH:D012878 Skin Neoplasms Doxorubicin 13.5515692506
MESH:D012878 Skin Neoplasms Glucose 13.5514993021
MESH:D012878 Skin Neoplasms sodium arsenite 13.5518572023 19524636
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 13.5516192470
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 3.8417203757 16767912 15625365
MESH:D013088 Spermatocele Diethylstilbestrol 15.7916002989 16709447
MESH:D013088 Spermatocele Ethinyl Estradiol 15.7916709447
MESH:D013088 Spermatocele Tamoxifen 15.7916709447
MESH:D013119 Spinal Cord Injuries Progesterone 8.4215862959 16503802
MESH:D013119 Spinal Cord Injuries Tamoxifen 8.4219457130
MESH:D016135 Spinal Dysraphism sodium arsenite 7.5712854658
MESH:D016135 Spinal Dysraphism Valproic Acid 7.5719490988
MESH:D013226 Status Epilepticus Valproic Acid 3.7912833885
MESH:D013274 Stomach Neoplasms arsenic trioxide 3.8217007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 3.8220155912 2093021
MESH:D013274 Stomach Neoplasms Ethanol 3.8218456281
MESH:D013274 Stomach Neoplasms Fluorouracil 3.8217498489 16951190 19084572 16424979 18567086 19015929 17172411 18396642 15786421 17522103
MESH:D013276 Stomach Ulcer Ethanol 2.9016755016 17918041 9211565 9562338 11906479 17189318
MESH:D019966 Substance-Related Disorders bisphenol A 3.2516045194 16684133
MESH:D013375 Substance Withdrawal Syndrome Diazepam 12.959754883
MESH:D013375 Substance Withdrawal Syndrome Ethanol 12.959754883
MESH:D013375 Substance Withdrawal Syndrome Pentobarbital 12.9511529278 9754883
MESH:D013398 Sudden Infant Death Oxygen 4.8012563064
MESH:D015173 Supratentorial Neoplasms Vincristine 5.1412837982
MESH:D013921 Thrombocytopenia 1-Naphthylisothiocyanate 4.1020133375
MESH:D019851 Thrombophilia Ethinyl Estradiol 2.9311994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.5215669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.1512697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 12.4219014326
MESH:D013964 Thyroid Neoplasms Dacarbazine 12.4211815960 15634649
MESH:D013964 Thyroid Neoplasms Doxorubicin 12.4217909728 16010429
MESH:D013964 Thyroid Neoplasms Phenobarbital 12.421399818
MESH:D013978 Tibial Fractures Estradiol 3.9319048282
MESH:D014062 Tongue Neoplasms Fluorouracil 3.3416280240
MESH:D016171 Torsades de Pointes arsenic trioxide 3.2315213294
MESH:D014123 Toxoplasmosis Ciprofloxacin 5.2720186551
MESH:D014178 Translocation, Genetic Valproic Acid 4.4817262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 3.783119515
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 22.1411780464 12973940 12845720 20435036
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 22.1417053015
MESH:D001749 Urinary Bladder Neoplasms Ciprofloxacin 22.1415028437 10741713
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 22.1416452187 17306315 16712894
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 22.1417653716
MESH:D001749 Urinary Bladder Neoplasms Quercetin 22.1416720314
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 22.1411723127 17306315 16712894 16452187
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 22.1416712894 17572228 8653321
MESH:D014564 Urogenital Abnormalities Valproic Acid 3.928888407
MESH:D014581 Urticaria Acetaminophen 2.3010982225
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 12.1416175088
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 12.1416803524
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 12.1411813266
MESH:D014591 Uterine Diseases bisphenol A 11.3114652134
MESH:D014591 Uterine Diseases Diethylstilbestrol 11.3114652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 7.1415809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 7.1414692618
MESH:D014605 Uveitis Cyclosporine 3.231336536
MESH:D014625 Vaginal Neoplasms Dacarbazine 9.1115577323
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 9.1116002989 16513791
MESH:D014652 Vascular Diseases sodium arsenite 3.6917056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.8412125929
MESH:D020301 Vasospasm, Intracranial Ibuprofen 4.4519057314
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.8715869587 14671159
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 3.5017638931 17334414 16364871 17678736
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.4915886252
MESH:D015430 Weight Gain Dietary Fats 3.1016723640
MESH:D014985 Xerophthalmia Cyclosporine 3.6917120751
Pathway ID Pathway Name
KEGG:04920 Adipocytokine signaling pathway
KEGG:04976 Bile secretion
REACT:15380 Diabetes pathways
REACT:1505 Integration of energy metabolism
REACT:474 Metabolism of carbohydrates
REACT:11193 Metabolism of vitamins and cofactors
KEGG:05200 Pathways in cancer
KEGG:05211 Renal cell carcinoma
REACT:15518 Transmembrane transport of small molecules
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA35875
    • No data
    Releated disease ID Related disease Name
    PA445208Pain
    Releated drug ID Related drug Name
    PA449088codeine
    PA450550morphine
    Drug Bank Top
    No data
    No data
    No data
    Drugbank ID Action Drug Name Description
    DB00292 inhibitor Etomidate Hypnotics and Sedatives;Anesthetics, Intravenous

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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