Annotation Detail for SLC2A5
Basic Information Top
| Gene Symbol: | SLC2A5 ( GLUT5 ) |
|---|---|
| Gene Full Name: | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| Band: | 1p36.23 |
| Quick Links | Entrez ID:6518; OMIM: 138230; Uniprot ID:GTR5_HUMAN; ENSEMBL ID: ENSG00000142583; HGNC ID: 11010 |
| Relate to Another Database: | SFARIGene; denovo-db |
| No data |
| Pathway ID | Pathway Name |
|---|---|
| hsa04973 | Carbohydrate digestion and absorption |
| Pathway ID | Pathway Name |
|---|---|
| Metabolism of carbohydrates | |
| Transmembrane transport of small molecules |
| No data |
| No data |
| Pathway ID | Pathway Name |
|---|---|
| 500345 | Hexose transport |
| 500350 | Class II GLUTs |
Related Diseases/Disorders| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| C435044 | 1-((1-O-octadecyl-2-O-methylglycero)phospho)-3-deoxy-myo-inositol | 1-((1-O-octadecyl-2-O-methylglycero)phospho)-3-deoxy-myo-inositol inhibits the reaction [Fructose results in increased expression of and results in increased activity of SLC2A5 protein] | decreases reaction|increases activity|increases expression | 15691865 |
| C085911 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Fructose results in increased expression of and results in increased activity of SLC2A5 protein] | decreases reaction|increases activity|increases expression | 15691865 |
| D000082 | Acetaminophen | Acetaminophen affects the expression of SLC2A5 mRNA | affects expression | 17562736 |
| D000242 | Cyclic AMP | Cyclic AMP affects the expression of SLC2A5 mRNA | affects expression | 8554516 |
| D000242 | Cyclic AMP | [Fructose results in increased abundance of Cyclic AMP] which results in increased stability of SLC2A5 mRNA | increases abundance|increases stability | 12820898 |
| D000242 | Cyclic AMP | [Forskolin results in increased abundance of Cyclic AMP] which results in increased expression of SLC2A5 protein | increases abundance|increases expression | 8037665 |
| D000242 | Cyclic AMP | [[Forskolin results in increased abundance of Cyclic AMP] which results in increased expression of SLC2A5 protein] which results in increased uptake of Fructose | increases abundance|increases expression|increases uptake | 8037665 |
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of SLC2A5 mRNA | affects expression | 16483693 |
| C006632 | arsenic trioxide | arsenic trioxide results in increased expression of SLC2A5 mRNA | increases expression | 17961207 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in decreased expression of SLC2A5 mRNA | decreases expression | 20064835 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in decreased expression of SLC2A5 mRNA | decreases expression | 19224547 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in decreased expression of SLC2A5 protein | decreases expression | 17544377 |
| D020111 | Chlorodiphenyl (54% Chlorine) | Chlorodiphenyl (54% Chlorine) results in increased expression of SLC2A5 mRNA | increases expression | 17961207 |
| D002994 | Clofibrate | Clofibrate results in decreased expression of SLC2A5 mRNA | decreases expression | 19224547 |
| D003513 | Cycloheximide | Cycloheximide inhibits the reaction [Fructose promotes the reaction [SLC2A5 protein results in increased uptake of Fructose]] | decreases reaction|increases reaction|increases uptake | 11123204 |
| D016572 | Cyclosporine | Cyclosporine results in decreased expression of SLC2A5 mRNA | decreases expression | 19224547 |
| D003609 | Dactinomycin | Dactinomycin inhibits the reaction [Fructose promotes the reaction [SLC2A5 protein results in increased uptake of Fructose]] | decreases reaction|increases reaction|increases uptake | 11123204 |
| D003609 | Dactinomycin | Dactinomycin inhibits the reaction [Fructose results in increased expression of SLC2A5 mRNA] | decreases reaction|increases expression | 11123204 |
| D003907 | Dexamethasone | Dexamethasone affects the expression of SLC2A5 mRNA | affects expression | 15102944 |
| D003907 | Dexamethasone | Dexamethasone promotes the reaction [Fructose results in increased activity of SLC2A5 protein] | increases activity|increases reaction | 18556366 |
| D003907 | Dexamethasone | Dexamethasone promotes the reaction [Fructose results in increased expression of SLC2A5 mRNA] | increases expression|increases reaction | 18556366 |
| D003907 | Dexamethasone | Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Fructose results in increased activity of SLC2A5 protein]] | decreases reaction|increases activity|increases reaction | 18556366 |
| D003907 | Dexamethasone | Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Fructose results in increased expression of SLC2A5 mRNA]] | decreases reaction|increases expression|increases reaction | 18556366 |
| D003994 | Bucladesine | Bucladesine results in increased expression of and results in increased stability of SLC2A5 mRNA | increases expression|increases stability | 12820898 |
| D003994 | Bucladesine | N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of and results in increased stability of SLC2A5 mRNA] | decreases reaction|increases expression|increases stability | 12820898 |
| D004052 | Diethylnitrosamine | Diethylnitrosamine results in decreased expression of SLC2A5 mRNA | decreases expression | 19638242 |
| D002117 | Calcitriol | Calcitriol results in decreased expression of SLC2A5 mRNA | decreases expression | 16002434 |
| D005227 | Fatty Acids | Fatty Acids results in increased expression of SLC2A5 protein | increases expression | 14705828 |
| D005576 | Forskolin | Forskolin promotes the reaction [Fructose results in increased expression of SLC2A5 mRNA] | increases expression|increases reaction | 12820898 |
| D005576 | Forskolin | Forskolin promotes the reaction [Glucose results in increased expression of SLC2A5 mRNA] | increases expression|increases reaction | 12820898 |
| D005576 | Forskolin | Forskolin results in increased expression of SLC2A5 mRNA | increases expression | 12820898 |
| D005576 | Forskolin | [Forskolin results in increased abundance of Cyclic AMP] which results in increased expression of SLC2A5 protein | increases abundance|increases expression | 8037665 |
| D005576 | Forskolin | [[Forskolin results in increased abundance of Cyclic AMP] which results in increased expression of SLC2A5 protein] which results in increased uptake of Fructose | increases abundance|increases expression|increases uptake | 8037665 |
| D005576 | Forskolin | Forskolin results in increased expression of and results in decreased degradation of SLC2A5 mRNA | decreases degradation|increases expression | 8037665 |
| D005632 | Fructose | SLC2A5 protein results in increased transport of Fructose | increases transport | 15014919 |
| D005632 | Fructose | Forskolin promotes the reaction [Fructose results in increased expression of SLC2A5 mRNA] | increases expression|increases reaction | 12820898 |
| D005632 | Fructose | Fructose promotes the reaction [PAIP2 protein binds to SLC2A5 3' UTR] | affects binding|increases reaction | 12820898 |
| D005632 | Fructose | [Fructose results in increased abundance of Cyclic AMP] which results in increased stability of SLC2A5 mRNA | increases abundance|increases stability | 12820898 |
| D005632 | Fructose | Fructose results in increased expression of SLC2A5 mRNA | increases expression | 12820898 8554516 |
| D005632 | Fructose | Fructose results in increased expression of SLC2A5 protein | increases expression | 8554516 |
| D005632 | Fructose | SLC2A5 protein results in increased transport of Fructose | increases transport | 16960373 17710649 1634504 |
| D005632 | Fructose | Fructose results in increased activity of SLC2A5 protein | increases activity | 19907007 |
| D005632 | Fructose | Fructose results in increased expression of SLC2A5 mRNA | increases expression | 19907007 17786952 12937289 12031501 |
| D005632 | Fructose | lactisole inhibits the reaction [Fructose results in increased expression of SLC2A5 mRNA] | decreases reaction|increases expression | 17786952 |
| D005632 | Fructose | SLC2A5 protein results in increased transport of Fructose | increases transport | 12031501 |
| D005632 | Fructose | Galactose inhibits the reaction [SLC2A5 protein results in increased transport of Fructose] | decreases reaction|increases transport | 7980458 |
| D005632 | Fructose | Glucose inhibits the reaction [SLC2A5 protein results in increased transport of Fructose] | decreases reaction|increases transport | 7980458 |
| D005632 | Fructose | SLC2A5 protein results in increased transport of Fructose | increases transport | 7980458 |
| D005632 | Fructose | 1-((1-O-octadecyl-2-O-methylglycero)phospho)-3-deoxy-myo-inositol inhibits the reaction [Fructose results in increased expression of and results in increased activity of SLC2A5 protein] | decreases reaction|increases activity|increases expression | 15691865 |
| D005632 | Fructose | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Fructose results in increased expression of and results in increased activity of SLC2A5 protein] | decreases reaction|increases activity|increases expression | 15691865 |
| D005632 | Fructose | Cycloheximide inhibits the reaction [Fructose promotes the reaction [SLC2A5 protein results in increased uptake of Fructose]] | decreases reaction|increases reaction|increases uptake | 11123204 |
| D005632 | Fructose | Dactinomycin inhibits the reaction [Fructose promotes the reaction [SLC2A5 protein results in increased uptake of Fructose]] | decreases reaction|increases reaction|increases uptake | 11123204 |
| D005632 | Fructose | Dactinomycin inhibits the reaction [Fructose results in increased expression of SLC2A5 mRNA] | decreases reaction|increases expression | 11123204 |
| D005632 | Fructose | Dexamethasone promotes the reaction [Fructose results in increased activity of SLC2A5 protein] | increases activity|increases reaction | 18556366 |
| D005632 | Fructose | Dexamethasone promotes the reaction [Fructose results in increased expression of SLC2A5 mRNA] | increases expression|increases reaction | 18556366 |
| D005632 | Fructose | [[Forskolin results in increased abundance of Cyclic AMP] which results in increased expression of SLC2A5 protein] which results in increased uptake of Fructose | increases abundance|increases expression|increases uptake | 8037665 |
| D005632 | Fructose | Fructose affects the expression of SLC2A5 mRNA | affects expression | 15150374 |
| D005632 | Fructose | Fructose analog results in increased activity of [SLC2A5 protein results in increased uptake of Fructose] | increases activity|increases uptake | 11518678 |
| D005632 | Fructose | Fructose analog results in increased expression of SLC2A5 mRNA | increases expression | 11518678 |
| D005632 | Fructose | Fructose promotes the reaction [SLC2A5 protein results in increased transport of Fructose] | increases reaction|increases transport | 9486174 |
| D005632 | Fructose | Fructose promotes the reaction [SLC2A5 protein results in increased uptake of Fructose] | increases reaction|increases uptake | 11123204 |
| D005632 | Fructose | Fructose results in increased activity of SLC2A5 protein | increases activity | 16920846 10554124 11123204 18400728 18556366 |
| D005632 | Fructose | Fructose results in increased expression of and results in increased activity of SLC2A5 protein | increases activity|increases expression | 15691865 |
| D005632 | Fructose | Fructose results in increased expression of SLC2A5 mRNA | increases expression | 18400728 8048533 15226456 18556366 15691865 9078534 9124564 11242478 16920846 11123204 11518678 9486174 8404647 10554124 10222385 16581195 9606981 |
| D005632 | Fructose | Fructose results in increased expression of SLC2A5 protein | increases expression | 15150374 8048533 16581195 8404647 9606981 |
| D005632 | Fructose | Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Fructose results in increased activity of SLC2A5 protein]] | decreases reaction|increases activity|increases reaction | 18556366 |
| D005632 | Fructose | Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Fructose results in increased expression of SLC2A5 mRNA]] | decreases reaction|increases expression|increases reaction | 18556366 |
| D005632 | Fructose | SLC2A5 protein results in increased transport of Fructose | increases transport | 9486174 15457374 |
| D005632 | Fructose | SLC2A5 protein results in increased uptake of Fructose | increases uptake | 11123204 11518678 |
| D005632 | Fructose | [Triiodothyronine co-treated with Fructose] results in increased expression of SLC2A5 mRNA | affects cotreatment|increases expression | 17485832 |
| D005632 | Fructose | Vanadates inhibits the reaction [Fructose results in increased activity of SLC2A5 protein] | decreases reaction|increases activity | 16920846 |
| D005632 | Fructose | Vanadates inhibits the reaction [Fructose results in increased expression of SLC2A5 mRNA] | decreases reaction|increases expression | 16920846 |
| D005632 | Fructose | wortmannin inhibits the reaction [Fructose results in increased expression of and results in increased activity of SLC2A5 protein] | decreases reaction|increases activity|increases expression | 15691865 |
| D005632 | Fructose | SLC2A5 protein results in increased metabolism of Fructose | increases metabolic processing | 16266770 |
| D005690 | Galactose | Galactose inhibits the reaction [SLC2A5 protein results in increased transport of Fructose] | decreases reaction|increases transport | 7980458 |
| D005947 | Glucose | Forskolin promotes the reaction [Glucose results in increased expression of SLC2A5 mRNA] | increases expression|increases reaction | 12820898 |
| D005947 | Glucose | Glucose promotes the reaction [PAIP2 protein binds to SLC2A5 3' UTR] | affects binding|increases reaction | 12820898 |
| D005947 | Glucose | Glucose results in increased expression of SLC2A5 mRNA | increases expression | 12820898 8554516 |
| D005947 | Glucose | Glucose results in increased expression of SLC2A5 protein | increases expression | 8554516 |
| D005947 | Glucose | SLC2A5 protein results in increased transport of Glucose | increases transport | 17710649 |
| D005947 | Glucose | Glucose results in increased expression of SLC2A5 mRNA | increases expression | 12937289 |
| D005947 | Glucose | Glucose inhibits the reaction [SLC2A5 protein results in increased transport of Fructose] | decreases reaction|increases transport | 7980458 |
| D005947 | Glucose | Glucose results in increased expression of SLC2A5 protein | increases expression | 8048533 |
| D007501 | Iron | Iron deficiency results in decreased expression of SLC2A5 mRNA | decreases expression | 20368581 |
| C099406 | L 742694 | L 742694 affects the expression of SLC2A5 mRNA | affects expression | 15102944 |
| C495512 | lactisole | lactisole inhibits the reaction [Fructose results in increased expression of SLC2A5 mRNA] | decreases reaction|increases expression | 17786952 |
| C029891 | lead chloride | lead chloride results in increased expression of SLC2A5 mRNA | increases expression | 17961207 |
| D015735 | Mifepristone | Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Fructose results in increased activity of SLC2A5 protein]] | decreases reaction|increases activity|increases reaction | 18556366 |
| D015735 | Mifepristone | Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Fructose results in increased expression of SLC2A5 mRNA]] | decreases reaction|increases expression|increases reaction | 18556366 |
| C035133 | mirtazapine | mirtazapine results in increased expression of SLC2A5 mRNA | increases expression | 16002093 |
| C063509 | N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide | N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of and results in increased stability of SLC2A5 mRNA] | decreases reaction|increases expression|increases stability | 12820898 |
| C025589 | ochratoxin A | ochratoxin A results in decreased expression of SLC2A5 mRNA | decreases expression | 16251485 |
| D010634 | Phenobarbital | Phenobarbital results in increased expression of SLC2A5 mRNA | increases expression | 19270015 |
| C006253 | pirinixic acid | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of SLC2A5 mRNA | affects binding|decreases expression|increases activity | 19710929 |
| C045950 | propiconazole | propiconazole results in decreased expression of SLC2A5 mRNA | decreases expression | 19423681 |
| D013395 | Sucrose | Sucrose results in increased expression of SLC2A5 mRNA | increases expression | 10222385 9124564 |
| C446685 | systhane | systhane results in decreased expression of SLC2A5 mRNA | decreases expression | 19423681 |
| D014284 | Triiodothyronine | [Triiodothyronine co-treated with Fructose] results in increased expression of SLC2A5 mRNA | affects cotreatment|increases expression | 17485832 |
| D013629 | Tamoxifen | Tamoxifen results in decreased expression of SLC2A5 mRNA | decreases expression | 19224547 |
| D013752 | Tetracycline | Tetracycline results in decreased expression of SLC2A5 mRNA | decreases expression | 19224547 |
| D014050 | Toluene | Toluene affects the expression of SLC2A5 mRNA | affects expression | 18653662 |
| D014212 | Tretinoin | Tretinoin results in increased expression of SLC2A5 mRNA | increases expression | 16054129 |
| D014212 | Tretinoin | Tretinoin results in increased expression of SLC2A5 protein | increases expression | 16960373 |
| C032910 | triadimefon | triadimefon results in decreased expression of SLC2A5 mRNA | decreases expression | 19423681 |
| D014635 | Valproic Acid | Valproic Acid results in decreased expression of SLC2A5 mRNA | decreases expression | 19224547 |
| D014638 | Vanadates | Vanadates inhibits the reaction [Fructose results in increased activity of SLC2A5 protein] | decreases reaction|increases activity | 16920846 |
| D014638 | Vanadates | Vanadates inhibits the reaction [Fructose results in increased expression of SLC2A5 mRNA] | decreases reaction|increases expression | 16920846 |
| C009687 | wortmannin | wortmannin inhibits the reaction [Fructose results in increased expression of and results in increased activity of SLC2A5 protein] | decreases reaction|increases activity|increases expression | 15691865 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000008 | Abdominal Neoplasms | Tamoxifen | 4.07 | 14745880 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Phenobarbital | 6.99 | 6195326 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Valproic Acid | 6.99 | 8875741 | |
| MESH:D000015 | Abnormalities, Multiple | Valproic Acid | 3.51 | 19490988 | |
| MESH:D000138 | Acidosis | Ammonium Chloride | 3.10 | 18287403 | |
| MESH:D055371 | Acute Lung Injury | pirinixic acid | 2.69 | 18653653 | |
| MESH:D000230 | Adenocarcinoma | arsenic trioxide | 3.89 | 19825857 11798837 | |
| MESH:D000230 | Adenocarcinoma | Benzo(a)pyrene | 3.89 | 20127859 20464547 | |
| MESH:D000236 | Adenoma | Benzo(a)pyrene | 5.69 | 6695378 | |
| MESH:D000236 | Adenoma | Diethylnitrosamine | 5.69 | 6695378 10737359 | |
| MESH:D018248 | Adenoma, Liver Cell | Diethylnitrosamine | 14.66 | 19061943 18056438 16434500 17162532 17620307 19052882 | |
| MESH:D018248 | Adenoma, Liver Cell | Phenobarbital | 14.66 | 17620307 | |
| MESH:D018248 | Adenoma, Liver Cell | pirinixic acid | 14.66 | 16434500 | |
| MESH:D000505 | Alopecia | Tretinoin | 3.25 | 15955085 | |
| MESH:D019896 | alpha 1-Antitrypsin Deficiency | Iron | 5.19 | 16640825 | |
| MESH:D000544 | Alzheimer Disease | Iron | 2.89 | 16640825 16563566 | |
| MESH:D000550 | Amblyopia | Valproic Acid | 4.76 | 17688650 | |
| MESH:D000740 | Anemia | Iron | 3.97 | 16434484 16566752 | |
| MESH:D018798 | Anemia, Iron-Deficiency | Iron | 4.24 | 17163184 17147795 17162259 16569441 17375513 | |
| MESH:D000756 | Anemia, Sideroblastic | Iron | 4.39 | 16910769 | |
| MESH:D000799 | Angioedema | Acetaminophen | 3.37 | 10982225 | |
| MESH:D001008 | Anxiety Disorders | Valproic Acid | 3.20 | 17497229 | |
| MESH:D017544 | Aortic Aneurysm, Abdominal | Benzo(a)pyrene | 3.62 | 19183758 | |
| MESH:D001145 | Arrhythmias, Cardiac | Iron | 3.97 | 16604332 | |
| MESH:D001169 | Arthritis, Experimental | Dexamethasone | 6.54 | 17659584 | |
| MESH:D001169 | Arthritis, Experimental | Tretinoin | 6.54 | 16412693 | |
| MESH:D001172 | Arthritis, Rheumatoid | Tretinoin | 2.14 | 16292516 | |
| MESH:D001249 | Asthma | Tretinoin | 2.19 | 16456186 | |
| MESH:D001260 | Ataxia Telangiectasia | Iron | 4.98 | 15336622 | |
| MESH:D050197 | Atherosclerosis | Iron | 3.43 | 16640825 16632123 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 2.60 | 18445737 | |
| MESH:D001321 | Autistic Disorder | Iron | 2.60 | 17352947 | |
| MESH:D001321 | Autistic Disorder | mirtazapine | 2.60 | 16648008 | |
| MESH:D001321 | Autistic Disorder | Valproic Acid | 2.60 | 16609825 18940202 18775368 18316065 15238991 18396377 18558336 17688650 18177632 17157402 18985861 17507914 20603192 19232924 19460635 | |
| MESH:D001424 | Bacterial Infections | Iron | 4.73 | 16640825 | |
| MESH:D001471 | Barrett Esophagus | Tretinoin | 3.96 | 16935849 | |
| MESH:D001714 | Bipolar Disorder | Valproic Acid | 2.83 | 20046352 17594078 | |
| MESH:D001778 | Blood Coagulation Disorders | arsenic trioxide | 18.59 | 16206674 | |
| MESH:D001778 | Blood Coagulation Disorders | Clofibrate | 18.59 | 19483382 | |
| MESH:D001778 | Blood Coagulation Disorders | pirinixic acid | 18.59 | 19483382 | |
| MESH:D001778 | Blood Coagulation Disorders | Tretinoin | 18.59 | 16206674 16197459 | |
| MESH:D001848 | Bone Diseases, Developmental | Valproic Acid | 3.10 | 8888407 | |
| MESH:D019046 | Bone Marrow Neoplasms | Dactinomycin | 5.06 | 14601052 | |
| MESH:D001943 | Breast Neoplasms | therapeutic | 15449313 | ||
| MESH:D001943 | Breast Neoplasms | Benzo(a)pyrene | 2.69 | 17474063 20146248 | |
| MESH:D001943 | Breast Neoplasms | Calcitriol | 2.69 | 11237771 | |
| MESH:D001943 | Breast Neoplasms | Diethylnitrosamine | 2.69 | 17474063 | |
| MESH:D001943 | Breast Neoplasms | ochratoxin A | 2.69 | 11921183 | |
| MESH:D001943 | Breast Neoplasms | Tamoxifen | 2.69 | 19189212 20065188 19189210 18351453 19084267 17242785 18629630 19289846 15668708 16273361 19200415 21138602 21152245 20005174 15565566 19103187 17893378 11161223 19115204 19059307 20859285 18855134 18815881 17261762 19155303 18425577 20544844 19487384 19011961 17049068 17440819 19288272 19221464 16873071 19066611 18984771 20390343 19244106 16818667 16202921 19410462 20135344 19142967 18821012 18997820 | |
| MESH:D001943 | Breast Neoplasms | Tretinoin | 2.69 | 16443354 16166294 16873071 | |
| MESH:D001997 | Bronchopulmonary Dysplasia | Tretinoin | 4.12 | 16813970 | |
| MESH:D002051 | Burkitt Lymphoma | arsenic trioxide | 3.90 | 11589617 | |
| MESH:D002252 | Carbon Tetrachloride Poisoning | Carbon Tetrachloride | 3.33 | 15700767 16124888 15673190 18705752 3786805 10355542 15721981 16011737 16227642 16097048 16050911 16192424 | |
| MESH:D018270 | Carcinoma, Ductal, Breast | Tamoxifen | 4.05 | 19066611 | |
| MESH:D018236 | Carcinoma, Embryonal | Tretinoin | 4.68 | 16168501 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 12.64 | 3084413 | |
| MESH:D006528 | Carcinoma, Hepatocellular | arsenic trioxide | 12.64 | 15553829 14691202 15073043 11135700 16217749 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Carbon Tetrachloride | 12.64 | 18788625 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Diethylnitrosamine | 12.64 | 16540662 19052882 20214788 17978847 18056438 20084675 18978308 19539802 16830150 18210153 19208518 18788625 18971187 20524982 16569478 16328049 21159647 18506893 16935385 3581430 17162532 17428255 17055752 16502159 10737359 18785209 16698587 16878318 16779866 19394651 18494052 19919837 18665156 20935162 19107877 20514400 11831363 3084413 16681979 17761372 19383236 16288022 20432363 17173139 19418558 20007298 19822196 19519916 18691550 19335982 20512989 18393292 10672840 19701751 20101231 17138121 20727157 19171122 16807293 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Phenobarbital | 12.64 | 1701930 6705139 20007298 17173139 20935162 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Tamoxifen | 12.64 | 16924424 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Tretinoin | 12.64 | 1917145 | |
| MESH:D002291 | Carcinoma, Papillary | arsenic trioxide | 4.40 | 19014326 | |
| MESH:D018288 | Carcinoma, Small Cell | arsenic trioxide | 3.71 | 12490120 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Benzo(a)pyrene | 6.62 | 20419170 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Calcitriol | 6.62 | 11237771 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Tretinoin | 6.62 | 16051514 16096774 | |
| MESH:D002295 | Carcinoma, Transitional Cell | Tamoxifen | 3.21 | 17572228 | |
| MESH:D009202 | Cardiomyopathies | Iron | 3.73 | 16640825 | |
| MESH:D002311 | Cardiomyopathy, Dilated | Iron | 3.29 | 16604332 | |
| MESH:D002386 | Cataract | Acetaminophen | 6.28 | 10977129 | |
| MESH:D002386 | Cataract | Tretinoin | 6.28 | 17460283 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Clofibrate | 9.37 | 1399818 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Cyclosporine | 9.37 | 12371664 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Diethylnitrosamine | 9.37 | 17174075 2727394 7505956 21159647 | |
| MESH:D002493 | Central Nervous System Diseases | Phenobarbital | 3.80 | 4080065 | |
| MESH:D002547 | Cerebral Palsy | Toluene | 5.38 | 9294310 | |
| MESH:D018290 | Cervical Intraepithelial Neoplasia | Tretinoin | 4.12 | 16129372 | |
| MESH:D002659 | Child Development Disorders, Pervasive | Valproic Acid | 2.53 | 20734317 | |
| MESH:D018281 | Cholangiocarcinoma | Diethylnitrosamine | 3.29 | 19052882 | |
| MESH:D002779 | Cholestasis | Cyclosporine | 6.60 | 19486331 | |
| MESH:D002779 | Cholestasis | pirinixic acid | 6.60 | 19176532 | |
| MESH:D002822 | Choriocarcinoma | Tretinoin | 4.68 | 16461808 | |
| MESH:D002972 | Cleft Palate | Tretinoin | 5.65 | 9407595 | |
| MESH:D002972 | Cleft Palate | triadimefon | 5.65 | 16781842 | |
| MESH:D003092 | Colitis | Tretinoin | 3.25 | 17035595 | |
| MESH:D003110 | Colonic Neoplasms | marker/mechanism | 19050079 | ||
| MESH:D003110 | Colonic Neoplasms | Dexamethasone | 3.82 | 15824018 | |
| MESH:D003110 | Colonic Neoplasms | Iron | 3.82 | 16640825 | |
| MESH:D015179 | Colorectal Neoplasms | arsenic trioxide | 1.85 | 20501625 | |
| MESH:D003327 | Coronary Disease | Fructose | 4.17 | 18504504 | |
| MESH:D023903 | Coronary Restenosis | arsenic trioxide | 3.74 | 12609071 | |
| MESH:D019465 | Craniofacial Abnormalities | arsenic trioxide | 10.78 | 10525206 | |
| MESH:D019465 | Craniofacial Abnormalities | Dexamethasone | 10.78 | 17728286 | |
| MESH:D019465 | Craniofacial Abnormalities | ochratoxin A | 10.78 | 20036863 | |
| MESH:D019465 | Craniofacial Abnormalities | Toluene | 10.78 | 9294310 | |
| MESH:D019465 | Craniofacial Abnormalities | Tretinoin | 10.78 | 9142499 9125849 9211117 17551590 9224671 14991402 16925845 9664655 10589399 8800419 | |
| MESH:D019465 | Craniofacial Abnormalities | triadimefon | 10.78 | 16875885 15834900 | |
| MESH:D019465 | Craniofacial Abnormalities | Valproic Acid | 10.78 | 17688650 16575769 8888407 | |
| MESH:D003643 | Death | Toluene | 5.19 | 6431079 | |
| MESH:D016757 | Death, Sudden, Cardiac | arsenic trioxide | 3.67 | 15213294 | |
| MESH:D003711 | Demyelinating Diseases | Tamoxifen | 3.91 | 19031437 | |
| MESH:D003866 | Depressive Disorder | mirtazapine | 5.00 | 18083778 | |
| MESH:D017449 | Dermatitis, Allergic Contact | Dexamethasone | 2.98 | 12438553 | |
| MESH:D003876 | Dermatitis, Atopic | pirinixic acid | 2.20 | 18249437 | |
| MESH:D003920 | Diabetes Mellitus | Iron | 4.06 | 16640825 16604332 | |
| MESH:D003921 | Diabetes Mellitus, Experimental | Fructose | 4.12 | 18603373 | |
| MESH:D003922 | Diabetes Mellitus, Type 1 | Iron | 3.20 | 16506275 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Diethylnitrosamine | 6.62 | 20387270 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Fructose | 6.62 | 18603373 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Iron | 6.62 | 16506275 | |
| MESH:D003928 | Diabetic Nephropathies | Tamoxifen | 3.09 | 19279558 | |
| MESH:D003967 | Diarrhea | Dexamethasone | 3.27 | 7237001 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 13.16 | 11461765 19370779 11834606 12392966 18071297 19164858 16227642 11421492 14725611 15968718 12705907 19923254 17906064 15619225 19739265 16109766 10663392 16081117 14986274 16485898 19416960 11739529 10915739 12958197 18713872 11743745 11287661 2444490 12153990 14550746 16781746 17562736 19085960 16393943 10774834 19420014 11529661 17522070 12540782 12594235 16177239 | |
| MESH:D056486 | Drug-Induced Liver Injury | Carbon Tetrachloride | 13.16 | 21278145 6884620 6623471 7120509 9327722 3786805 10915739 2869522 15968718 7179309 7440962 15027814 17522070 19336974 15998439 10092053 19085960 3732212 4309450 16227642 16177239 11566570 | |
| MESH:D056486 | Drug-Induced Liver Injury | Chlorodiphenyl (54% Chlorine) | 13.16 | 17851650 | |
| MESH:D056486 | Drug-Induced Liver Injury | Diethylnitrosamine | 13.16 | 19107877 | |
| MESH:D056486 | Drug-Induced Liver Injury | Tetracycline | 13.16 | 17522070 | |
| MESH:D056486 | Drug-Induced Liver Injury | Valproic Acid | 13.16 | 19641884 1733752 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 3.62 | 19426721 | |
| MESH:D050171 | Dyslipidemias | Clofibrate | 3.73 | 16707586 | |
| MESH:D004421 | Dystonia | Phenobarbital | 9.01 | 1851702 | |
| MESH:D004421 | Dystonia | Valproic Acid | 9.01 | 1851702 | |
| MESH:D004485 | Eczema | Dexamethasone | 4.02 | 12438553 | |
| MESH:D004487 | Edema | Dexamethasone | 5.56 | 19703484 | |
| MESH:D004487 | Edema | pirinixic acid | 5.56 | 12083418 | |
| MESH:D004489 | Edema, Cardiac | Tretinoin | 3.99 | 18230668 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Calcitriol | 7.76 | 15138306 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Tamoxifen | 7.76 | 19031437 | |
| MESH:D016889 | Endometrial Neoplasms | Tamoxifen | 6.40 | 20544844 16202921 19155303 17893378 | |
| MESH:D016889 | Endometrial Neoplasms | Tretinoin | 6.40 | 16569247 | |
| MESH:D004715 | Endometriosis | Mifepristone | 3.97 | 16134523 | |
| MESH:D004831 | Epilepsies, Myoclonic | Phenobarbital | 9.28 | 3659116 | |
| MESH:D004831 | Epilepsies, Myoclonic | Valproic Acid | 9.28 | 17275665 3659116 | |
| MESH:D004828 | Epilepsies, Partial | Phenobarbital | 8.40 | 3922381 11558140 | |
| MESH:D004828 | Epilepsies, Partial | Valproic Acid | 8.40 | 3922381 16628512 | |
| MESH:D004827 | Epilepsy | Phenobarbital | 5.82 | 20417680 | |
| MESH:D004827 | Epilepsy | Valproic Acid | 5.82 | 18234410 20417680 | |
| MESH:D004832 | Epilepsy, Absence | Phenobarbital | 7.56 | 6401628 | |
| MESH:D004832 | Epilepsy, Absence | Valproic Acid | 7.56 | 6426943 7562514 6254150 | |
| MESH:D017029 | Epilepsy, Complex Partial | Phenobarbital | 9.79 | 7750514 | |
| MESH:D017029 | Epilepsy, Complex Partial | Valproic Acid | 9.79 | 7750514 | |
| MESH:D004830 | Epilepsy, Tonic-Clonic | Phenobarbital | 8.93 | 3659116 | |
| MESH:D004830 | Epilepsy, Tonic-Clonic | Valproic Acid | 8.93 | 3659116 | |
| MESH:D004931 | Esophageal Achalasia | Diethylnitrosamine | 4.64 | 16302075 | |
| MESH:D004938 | Esophageal Neoplasms | arsenic trioxide | 3.97 | 12903497 | |
| MESH:D004938 | Esophageal Neoplasms | Benzo(a)pyrene | 3.97 | 16530937 | |
| MESH:D005124 | Eye Abnormalities | Tretinoin | 3.23 | 9664655 16938888 | |
| MESH:D005234 | Fatty Liver | arsenic trioxide | 53.36 | 15073043 | |
| MESH:D005234 | Fatty Liver | Carbon Tetrachloride | 53.36 | 15959796 12631006 12795759 19224547 61145 17595544 16239168 16045604 | |
| MESH:D005234 | Fatty Liver | Clofibrate | 53.36 | 19224547 | |
| MESH:D005234 | Fatty Liver | Cyclosporine | 53.36 | 19224547 | |
| MESH:D005234 | Fatty Liver | Diethylnitrosamine | 53.36 | 21071580 20387270 | |
| MESH:D005234 | Fatty Liver | Fructose | 53.36 | 18641190 19196556 18395287 | |
| MESH:D005234 | Fatty Liver | Iron | 53.36 | 16640825 | |
| MESH:D005234 | Fatty Liver | pirinixic acid | 53.36 | 20131406 19236843 | |
| MESH:D005234 | Fatty Liver | Tamoxifen | 53.36 | 14986274 19224547 | |
| MESH:D005234 | Fatty Liver | Tetracycline | 53.36 | 16917069 19224547 | |
| MESH:D005234 | Fatty Liver | Valproic Acid | 53.36 | 14986274 19224547 | |
| MESH:D052776 | Female Urogenital Diseases | Tamoxifen | 2.94 | 16709447 | |
| MESH:D005315 | Fetal Diseases | Valproic Acid | 4.41 | 16575769 | |
| MESH:D005317 | Fetal Growth Retardation | Valproic Acid | 3.69 | 8888407 18558336 | |
| MESH:D005329 | Fetishism (Psychiatric) | mirtazapine | 6.84 | 18439117 | |
| MESH:D018221 | Fibromatosis, Abdominal | Tamoxifen | 4.06 | 14745880 | |
| MESH:D018222 | Fibromatosis, Aggressive | Tamoxifen | 3.72 | 19069698 | |
| MESH:D005355 | Fibrosis | Carbon Tetrachloride | 17.49 | 18705752 | |
| MESH:D005355 | Fibrosis | Cyclosporine | 17.49 | 12639820 12168785 | |
| MESH:D005355 | Fibrosis | Fructose | 17.49 | 18504504 | |
| MESH:D005355 | Fibrosis | Tretinoin | 17.49 | 17994277 | |
| MESH:D005621 | Friedreich Ataxia | Iron | 4.97 | 16604332 16640825 | |
| MESH:D005706 | Gallbladder Neoplasms | arsenic trioxide | 3.82 | 16904648 | |
| MESH:D005756 | Gastritis | Acetaminophen | 3.20 | 16983495 | |
| MESH:D005885 | Gingival Hyperplasia | Cyclosporine | 3.75 | 8708960 | |
| MESH:D005909 | Glioblastoma | Tretinoin | 2.70 | 17312396 | |
| MESH:D018149 | Glucose Intolerance | Fructose | 4.89 | 19165636 | |
| MESH:D006258 | Head and Neck Neoplasms | Tretinoin | 2.87 | 16096774 | |
| MESH:D006317 | Hearing Loss, Noise-Induced | Tretinoin | 4.68 | 16084493 | |
| MESH:D006330 | Heart Defects, Congenital | Benzo(a)pyrene | 5.79 | 20471113 | |
| MESH:D006330 | Heart Defects, Congenital | Tretinoin | 5.79 | 14991402 9664655 | |
| MESH:D006333 | Heart Failure | pirinixic acid | 2.24 | 20558911 | |
| MESH:D006432 | Hemochromatosis | Iron | 4.15 | 17255318 16640825 17053826 16604332 16574947 17236123 | |
| MESH:D006457 | Hemoglobinuria, Paroxysmal | Cyclosporine | 3.95 | 15720958 | |
| MESH:D006486 | Hemosiderosis | Iron | 4.74 | 16604332 | |
| MESH:D006505 | Hepatitis | Carbon Tetrachloride | 3.16 | 19900420 19110552 | |
| MESH:D006525 | Hepatitis, Viral, Human | Iron | 4.99 | 16640825 | |
| MESH:D006527 | Hepatolenticular Degeneration | Iron | 4.48 | 17182432 | |
| MESH:D006529 | Hepatomegaly | Iron | 27.90 | 16890145 | |
| MESH:D006529 | Hepatomegaly | Phenobarbital | 27.90 | 16109766 | |
| MESH:D006529 | Hepatomegaly | pirinixic acid | 27.90 | 19772884 19176532 18467677 16221962 | |
| MESH:D006529 | Hepatomegaly | propiconazole | 27.90 | 17178689 17178688 | |
| MESH:D006529 | Hepatomegaly | systhane | 27.90 | 17178689 17178688 | |
| MESH:D006529 | Hepatomegaly | triadimefon | 27.90 | 17178688 17178689 | |
| MESH:D006548 | Hernia, Diaphragmatic | Dexamethasone | 2.89 | 7520565 | |
| MESH:D015658 | HIV Infections | Iron | 3.42 | 16597321 | |
| MESH:D006849 | Hydrocephalus | Valproic Acid | 4.40 | 17688650 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 6.41 | 16870215 | |
| MESH:D006930 | Hyperalgesia | Tretinoin | 6.41 | 16870215 | |
| MESH:D006932 | Hyperbilirubinemia | Carbon Tetrachloride | 4.07 | 16899240 | |
| MESH:D017681 | Hypereosinophilic Syndrome | Tretinoin | 4.11 | 16778211 | |
| MESH:D006943 | Hyperglycemia | pirinixic acid | 2.78 | 20558911 | |
| MESH:D006946 | Hyperinsulinism | Fructose | 4.51 | 18360027 18563319 15752949 19008412 14757778 | |
| MESH:D006949 | Hyperlipidemias | Fructose | 4.33 | 15752949 | |
| MESH:D006973 | Hypertension | Cyclosporine | 7.67 | 10903974 | |
| MESH:D006973 | Hypertension | Dexamethasone | 7.67 | 17042910 | |
| MESH:D006973 | Hypertension | Fructose | 7.67 | 14568997 16843071 14573337 14633139 19008412 | |
| MESH:D006975 | Hypertension, Portal | Carbon Tetrachloride | 3.63 | 15338365 | |
| MESH:D015228 | Hypertriglyceridemia | Fructose | 4.67 | 19799862 19342510 | |
| MESH:D007006 | Hypogonadism | Iron | 4.07 | 16640825 | |
| MESH:D007037 | Hypothyroidism | Iron | 4.63 | 16640825 | |
| MESH:D007249 | Inflammation | Dexamethasone | 6.92 | 11099482 8960868 | |
| MESH:D007249 | Inflammation | Diethylnitrosamine | 6.92 | 18785209 | |
| MESH:D007249 | Inflammation | Tamoxifen | 6.92 | 19457130 | |
| MESH:D007333 | Insulin Resistance | Fructose | 6.63 | 18057795 19008412 18981581 17133782 14633139 19586609 18563319 19342510 19799862 14757778 14573337 | |
| MESH:D007333 | Insulin Resistance | pirinixic acid | 6.63 | 16306350 | |
| MESH:D007410 | Intestinal Diseases | Tretinoin | 3.32 | 17994277 | |
| MESH:D019189 | Iron Metabolism Disorders | Iron | 4.61 | 17163184 | |
| MESH:D007569 | Jaw Abnormalities | Tretinoin | 9.15 | 17551590 15992940 | |
| MESH:D007569 | Jaw Abnormalities | triadimefon | 9.15 | 15834900 15992940 | |
| MESH:D007638 | Keratoconjunctivitis Sicca | Cyclosporine | 3.97 | 15604871 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 8.55 | 12587719 15629191 | |
| MESH:D007674 | Kidney Diseases | Cyclosporine | 8.55 | 18776723 10903974 8314463 | |
| MESH:D007674 | Kidney Diseases | ochratoxin A | 8.55 | 11409539 | |
| MESH:D007680 | Kidney Neoplasms | Cyclosporine | 10.40 | 12371664 | |
| MESH:D007680 | Kidney Neoplasms | ochratoxin A | 10.40 | 16251485 | |
| MESH:D007680 | Kidney Neoplasms | Tamoxifen | 10.40 | 18625569 | |
| MESH:D007938 | Leukemia | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | 9.16 | 12970779 | |
| MESH:D007938 | Leukemia | arsenic trioxide | 9.16 | 15070760 | |
| MESH:D007938 | Leukemia | Tretinoin | 9.16 | 17143497 | |
| MESH:D015459 | Leukemia-Lymphoma, Adult T-Cell | arsenic trioxide | 3.38 | 17077332 12560223 | |
| MESH:D007948 | Leukemia, Monocytic, Acute | arsenic trioxide | 3.84 | 16972261 | |
| MESH:D015464 | Leukemia, Myelogenous, Chronic, BCR-ABL Positive | arsenic trioxide | 3.08 | 14633726 | |
| MESH:D007951 | Leukemia, Myeloid | arsenic trioxide | 8.09 | 19077051 | |
| MESH:D007951 | Leukemia, Myeloid | Tretinoin | 8.09 | 16482212 16932348 19285840 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | arsenic trioxide | 5.50 | 17050201 19850784 16467208 20471514 16968895 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | Tretinoin | 5.50 | 17596541 16294345 19850784 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | Valproic Acid | 5.50 | 16294345 17596541 | |
| MESH:D015473 | Leukemia, Promyelocytic, Acute | arsenic trioxide | 6.59 | 19035177 16112521 17649720 15336539 15213294 11468182 19075265 19225113 16891316 17712046 16823087 11161223 19642359 12018890 17107899 9834237 17869043 16330433 15622746 16966277 17217047 15748426 12712474 12679006 16331271 | |
| MESH:D015473 | Leukemia, Promyelocytic, Acute | Tretinoin | 6.59 | 19075265 19642359 16891316 17107899 17301526 17217047 16788101 16140955 16823087 17339181 17649720 17712046 16935935 17368321 17294898 19029980 17361223 15748426 12679006 16331271 19225113 9834237 16766008 17506722 19035177 | |
| MESH:D015458 | Leukemia, T-Cell | arsenic trioxide | 3.91 | 16882451 | |
| MESH:D020961 | Lewy Body Disease | Iron | 4.97 | 16563566 | |
| MESH:D017880 | Limb Deformities, Congenital | Tretinoin | 2.97 | 9224671 | |
| MESH:D008064 | Lipidoses | Tamoxifen | 2.82 | 15342952 17567588 | |
| MESH:D008103 | Liver Cirrhosis | Carbon Tetrachloride | 13.57 | 16239168 11903743 11408273 17334410 21278145 17174718 16221502 17157831 16943688 | |
| MESH:D008103 | Liver Cirrhosis | Diethylnitrosamine | 13.57 | 20032147 18522880 19638242 18665156 18407596 | |
| MESH:D008103 | Liver Cirrhosis | Iron | 13.57 | 16640825 | |
| MESH:D008103 | Liver Cirrhosis | Phenobarbital | 13.57 | 21047994 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Carbon Tetrachloride | 5.98 | 15650968 12741479 14748882 17708605 16136751 12632512 16097048 18339082 17900296 17640975 16248980 10355542 12389079 15123356 15057751 14716833 17698563 17525996 17922224 15876570 16638106 18156304 18317297 12609069 18210741 12667390 20821823 18420326 15893842 18418968 17714472 15673190 14716496 17721639 17565644 12632514 17823541 12445421 18705752 18279442 12546737 18205269 14724832 18187930 17944888 17976157 18395914 17766677 18006644 15959796 18376398 16192424 18481824 17761835 12445418 12586293 17557913 16027843 16015684 15730626 18277467 16011737 15370692 13678700 11481614 18395095 18472094 15996030 15052691 12958196 18251166 15362042 12649538 18429990 14620537 17631135 12898905 18263696 16033810 16116963 17869086 18472332 18166357 14512876 18054572 12666154 17481882 17805973 15925388 15931870 15338365 15818738 18412020 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Dexamethasone | 5.98 | 16718785 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | pirinixic acid | 5.98 | 15474484 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Tamoxifen | 5.98 | 18564211 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Tretinoin | 5.98 | 16248980 18397230 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 14.01 | 19784758 16611625 16610002 12587719 19460945 11587558 12969438 19014921 | |
| MESH:D008107 | Liver Diseases | Carbon Tetrachloride | 14.01 | 17285989 16964402 15720792 15830285 16246199 | |
| MESH:D008107 | Liver Diseases | Diethylnitrosamine | 14.01 | 17034775 | |
| MESH:D008107 | Liver Diseases | Phenobarbital | 14.01 | 19363144 | |
| MESH:D008107 | Liver Diseases | propiconazole | 14.01 | 19363144 | |
| MESH:D008107 | Liver Diseases | triadimefon | 14.01 | 19363144 | |
| MESH:D008108 | Liver Diseases, Alcoholic | Iron | 4.55 | 16737972 17207112 | |
| MESH:D017093 | Liver Failure | Carbon Tetrachloride | 3.71 | 15123358 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 8.07 | 17185352 16871587 | |
| MESH:D017114 | Liver Failure, Acute | Carbon Tetrachloride | 8.07 | 16899240 14706259 | |
| MESH:D008113 | Liver Neoplasms | arsenic trioxide | 30.10 | 14682389 | |
| MESH:D008113 | Liver Neoplasms | Benzo(a)pyrene | 30.10 | 21137059 20195826 | |
| MESH:D008113 | Liver Neoplasms | Carbon Tetrachloride | 30.10 | 19294768 | |
| MESH:D008113 | Liver Neoplasms | Diethylnitrosamine | 30.10 | 20118626 20492335 20101389 19256749 19850985 19294768 19073162 19638242 19642983 20405173 21071580 19426721 18978307 21047994 2422723 21278145 19255062 19812893 19254457 10737359 21167192 18754104 18977376 16942905 15175105 20452335 19090486 19499222 20434301 18644402 19551842 9163691 15885732 20137499 2862719 19833225 20501860 19427195 19996281 12771043 18648771 19690152 20583210 12112319 | |
| MESH:D008113 | Liver Neoplasms | Iron | 30.10 | 16640825 20302851 | |
| MESH:D008113 | Liver Neoplasms | Phenobarbital | 30.10 | 8742319 15975961 19073162 21047994 19482888 19812893 | |
| MESH:D008113 | Liver Neoplasms | pirinixic acid | 30.10 | 15890375 16377806 20007298 | |
| MESH:D008113 | Liver Neoplasms | propiconazole | 30.10 | 19028983 | |
| MESH:D008113 | Liver Neoplasms | Tamoxifen | 30.10 | 16684651 | |
| MESH:D008113 | Liver Neoplasms | triadimefon | 30.10 | 19028983 | |
| MESH:D008114 | Liver Neoplasms, Experimental | arsenic trioxide | 23.67 | 20377131 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Carbon Tetrachloride | 23.67 | 12014681 15583823 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Diethylnitrosamine | 23.67 | 18282651 18253720 16842330 19009564 19004024 19126423 2563599 16267830 21159647 18079962 17854601 17942915 9362446 18544905 17174075 19539802 18308698 3124819 19519916 18775883 18164116 18093689 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Phenobarbital | 23.67 | 1399818 18308698 17172636 6150874 2563599 | |
| MESH:D008114 | Liver Neoplasms, Experimental | propiconazole | 23.67 | 17178689 | |
| MESH:D008114 | Liver Neoplasms, Experimental | systhane | 23.67 | 17178689 | |
| MESH:D008114 | Liver Neoplasms, Experimental | triadimefon | 23.67 | 17178689 | |
| MESH:D008133 | Long QT Syndrome | arsenic trioxide | 3.00 | 15213294 | |
| MESH:D017563 | Lung Diseases, Interstitial | Valproic Acid | 3.79 | 17228818 | |
| MESH:D008175 | Lung Neoplasms | arsenic trioxide | 7.63 | 11798837 19825857 | |
| MESH:D008175 | Lung Neoplasms | Benzo(a)pyrene | 7.63 | 17053015 20135361 20464547 18569708 18520028 20869020 6695378 18816296 20064080 | |
| MESH:D008175 | Lung Neoplasms | Dexamethasone | 7.63 | 15824018 11195469 | |
| MESH:D008175 | Lung Neoplasms | Diethylnitrosamine | 7.63 | 20970405 21163286 6695378 20512841 | |
| MESH:D008175 | Lung Neoplasms | Iron | 7.63 | 16640825 | |
| MESH:D008175 | Lung Neoplasms | Tamoxifen | 7.63 | 18625569 | |
| MESH:D008268 | Macular Degeneration | Iron | 3.71 | 16640825 | |
| MESH:D015674 | Mammary Neoplasms, Animal | Tamoxifen | 3.30 | 19428831 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | ochratoxin A | 5.52 | 11921183 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Tamoxifen | 5.52 | 14580682 16827153 11731420 19196722 19196723 | |
| MESH:D020149 | Manganese Poisoning | Tamoxifen | 4.07 | 19453300 | |
| MESH:D008527 | Medulloblastoma | Tretinoin | 2.59 | 17453147 | |
| MESH:D008545 | Melanoma | Glucose | 4.65 | 14993021 | |
| MESH:D008545 | Melanoma | Tamoxifen | 4.65 | 19393235 12393984 | |
| MESH:D008545 | Melanoma | Tretinoin | 4.65 | 16752155 | |
| MESH:D018328 | Melanoma, Amelanotic | Tamoxifen | 3.72 | 15990972 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 3.11 | 19513568 | |
| MESH:D008591 | Meningomyelocele | Tretinoin | 3.97 | 16940565 | |
| MESH:D001523 | Mental Disorders | mirtazapine | 4.91 | 16856516 | |
| MESH:D008607 | Mental Retardation | Toluene | 3.48 | 9294310 | |
| MESH:D024821 | Metabolic Syndrome X | Fructose | 4.44 | 19165636 18497449 17261469 16815490 17098227 | |
| MESH:D008664 | Metal Metabolism, Inborn Errors | Cyclosporine | 4.31 | 16801185 | |
| MESH:D008850 | Microphthalmos | ochratoxin A | 5.35 | 20036863 | |
| MESH:D008881 | Migraine Disorders | Valproic Acid | 2.86 | 18765137 18803445 | |
| MESH:D020326 | Migraine without Aura | Cyclic AMP | 4.71 | 11304026 | |
| MESH:D019957 | Motor Skills Disorders | Toluene | 4.80 | 9294310 | |
| MESH:D009062 | Mouth Neoplasms | Benzo(a)pyrene | 2.83 | 16381670 | |
| MESH:D009101 | Multiple Myeloma | arsenic trioxide | 6.32 | 15949261 19549372 14977855 11468182 19417148 | |
| MESH:D009101 | Multiple Myeloma | Dexamethasone | 6.32 | 15867202 16118317 15744524 | |
| MESH:D020528 | Multiple Sclerosis, Chronic Progressive | Iron | 5.20 | 17086897 | |
| MESH:D009135 | Muscular Diseases | pirinixic acid | 3.05 | 16239165 | |
| MESH:D009139 | Musculoskeletal Abnormalities | Valproic Acid | 3.61 | 8888407 | |
| MESH:D009181 | Mycoses | Iron | 4.99 | 16640825 | |
| MESH:D009182 | Mycosis Fungoides | arsenic trioxide | 4.20 | 18349030 | |
| MESH:D009190 | Myelodysplastic Syndromes | arsenic trioxide | 15.29 | 16882451 16105982 | |
| MESH:D009190 | Myelodysplastic Syndromes | Dexamethasone | 15.29 | 9809623 | |
| MESH:D009190 | Myelodysplastic Syndromes | Tretinoin | 15.29 | 17596541 | |
| MESH:D009190 | Myelodysplastic Syndromes | Valproic Acid | 15.29 | 17596541 | |
| MESH:D009203 | Myocardial Infarction | pirinixic acid | 1.94 | 19151258 | |
| MESH:D017202 | Myocardial Ischemia | Iron | 4.07 | 16604332 | |
| MESH:D015428 | Myocardial Reperfusion Injury | Iron | 7.42 | 16604332 | |
| MESH:D015428 | Myocardial Reperfusion Injury | pirinixic acid | 7.42 | 16411023 | |
| MESH:D020191 | Myoclonic Epilepsies, Progressive | Phenobarbital | 4.01 | 17484760 | |
| MESH:D009361 | Neoplasm Invasiveness | arsenic trioxide | 3.52 | 16624393 | |
| MESH:D009362 | Neoplasm Metastasis | Diethylnitrosamine | 5.05 | 3581430 9029167 | |
| MESH:D009362 | Neoplasm Metastasis | Tamoxifen | 5.05 | 19393235 | |
| MESH:D009364 | Neoplasm Recurrence, Local | marker/mechanism | 19050079 | ||
| MESH:D009364 | Neoplasm Recurrence, Local | Tamoxifen | 2.35 | 19410462 | |
| MESH:D009369 | Neoplasms | Benzo(a)pyrene | 6.76 | 11141357 | |
| MESH:D009369 | Neoplasms | pirinixic acid | 6.76 | 17405874 | |
| MESH:D009369 | Neoplasms | Tretinoin | 6.76 | 16946489 16594593 | |
| MESH:D009376 | Neoplasms, Hormone-Dependent | Tamoxifen | 3.53 | 19200415 19196722 19189210 | |
| MESH:D009395 | Nephritis, Interstitial | Tetracycline | 4.31 | 9884423 | |
| MESH:D009402 | Nephrosis, Lipoid | Cyclosporine | 3.97 | 17954296 | |
| MESH:D009404 | Nephrotic Syndrome | Cyclosporine | 8.18 | 18481113 19348381 | |
| MESH:D009404 | Nephrotic Syndrome | Iron | 8.18 | 17178036 | |
| MESH:D009421 | Nervous System Malformations | Tretinoin | 3.34 | 9125849 | |
| MESH:D009436 | Neural Tube Defects | arsenic trioxide | 14.84 | 10525206 | |
| MESH:D009436 | Neural Tube Defects | ochratoxin A | 14.84 | 20036863 | |
| MESH:D009436 | Neural Tube Defects | Tretinoin | 14.84 | 9142499 | |
| MESH:D009436 | Neural Tube Defects | Valproic Acid | 14.84 | 8888407 16359493 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 11.92 | 18514411 | |
| MESH:D019636 | Neurodegenerative Diseases | Diethylnitrosamine | 11.92 | 20387270 | |
| MESH:D019636 | Neurodegenerative Diseases | Iron | 11.92 | 16604332 17296847 | |
| MESH:D009461 | Neurologic Manifestations | Diethylnitrosamine | 4.64 | 20387270 | |
| MESH:D052556 | Niemann-Pick Disease, Type C | Clofibrate | 4.48 | 9802331 | |
| MESH:D009765 | Obesity | Fructose | 4.40 | 18585860 17707055 | |
| MESH:D009765 | Obesity | pirinixic acid | 4.40 | 20558911 | |
| MESH:D010003 | Osteoarthritis | Iron | 3.68 | 16640825 | |
| MESH:D010018 | Osteomalacia | Phenobarbital | 3.90 | 17016548 | |
| MESH:D010024 | Osteoporosis | Iron | 3.57 | 16640825 16648989 | |
| MESH:D010051 | Ovarian Neoplasms | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | 9.99 | 16211241 | |
| MESH:D010051 | Ovarian Neoplasms | arsenic trioxide | 9.99 | 12452020 19769630 16624393 | |
| MESH:D010051 | Ovarian Neoplasms | Mifepristone | 9.99 | 16525653 | |
| MESH:D010051 | Ovarian Neoplasms | Tretinoin | 9.99 | 16936753 | |
| MESH:D010146 | Pain | Acetaminophen | 5.35 | 16870215 | |
| MESH:D010146 | Pain | Tretinoin | 5.35 | 16870215 | |
| MESH:D010190 | Pancreatic Neoplasms | arsenic trioxide | 10.77 | 15580305 | |
| MESH:D010190 | Pancreatic Neoplasms | Diethylnitrosamine | 10.77 | 16540662 | |
| MESH:D010190 | Pancreatic Neoplasms | Phenobarbital | 10.77 | 16965848 | |
| MESH:D010190 | Pancreatic Neoplasms | Tretinoin | 10.77 | 15976015 | |
| MESH:D010212 | Papilloma | Iron | 4.03 | 12065085 | |
| MESH:D010235 | Paraganglioma | arsenic trioxide | 3.73 | 19927285 | |
| MESH:D020447 | Parasomnias | Iron | 5.54 | 17352947 | |
| MESH:D010300 | Parkinson Disease | Iron | 3.14 | 16640825 16563566 | |
| MESH:D010391 | Pemphigoid, Bullous | Tetracycline | 4.96 | 11026799 | |
| MESH:D010900 | Pituitary Diseases | Iron | 5.20 | 16604332 | |
| MESH:D011041 | Poisoning | Iron | 3.87 | 16604332 | |
| MESH:D017119 | Porphyria Cutanea Tarda | Iron | 4.54 | 16640825 | |
| MESH:D011230 | Precancerous Conditions | Cyclosporine | 13.01 | 12371664 | |
| MESH:D011230 | Precancerous Conditions | Diethylnitrosamine | 13.01 | 2563599 | |
| MESH:D011230 | Precancerous Conditions | Phenobarbital | 13.01 | 2563599 | |
| MESH:D054198 | Precursor Cell Lymphoblastic Leukemia-Lymphoma | Dexamethasone | 3.27 | 21297632 | |
| MESH:D011225 | Pre-Eclampsia | Iron | 4.06 | 16640825 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | Valproic Acid | 3.37 | 20603192 | |
| MESH:D017096 | Prion Diseases | Tetracycline | 4.95 | 10903871 | |
| MESH:D011470 | Prostatic Hyperplasia | Calcitriol | 4.31 | 15572423 | |
| MESH:D011471 | Prostatic Neoplasms | arsenic trioxide | 2.18 | 19131511 | |
| MESH:D011471 | Prostatic Neoplasms | Benzo(a)pyrene | 2.18 | 17292933 | |
| MESH:D011471 | Prostatic Neoplasms | Calcitriol | 2.18 | 16644109 15754350 12479363 18247401 16289102 | |
| MESH:D011471 | Prostatic Neoplasms | Tamoxifen | 2.18 | 15067354 | |
| MESH:D011507 | Proteinuria | Tretinoin | 3.18 | 16636307 | |
| MESH:D011528 | Protozoan Infections | Iron | 5.54 | 16640825 | |
| MESH:D019310 | Pseudolymphoma | Phenobarbital | 10.61 | 12752131 | |
| MESH:D019310 | Pseudolymphoma | Valproic Acid | 10.61 | 12752131 11422049 | |
| MESH:D011565 | Psoriasis | Cyclosporine | 2.05 | 16882103 | |
| MESH:D011625 | Pterygium | Tretinoin | 4.33 | 16723453 | |
| MESH:D015427 | Reperfusion Injury | pirinixic acid | 2.15 | 19058328 | |
| MESH:D012128 | Respiratory Distress Syndrome, Adult | Dexamethasone | 3.59 | 18379247 11700416 | |
| MESH:D012148 | Restless Legs Syndrome | Iron | 4.20 | 16930377 | |
| MESH:D012208 | Rhabdomyosarcoma | Tretinoin | 9.44 | 16116481 16283617 | |
| MESH:D012208 | Rhabdomyosarcoma | Valproic Acid | 9.44 | 19155313 | |
| MESH:D012512 | Sarcoma, Ewing's | arsenic trioxide | 9.12 | 16646077 | |
| MESH:D012512 | Sarcoma, Ewing's | Dactinomycin | 9.12 | 14601052 | |
| MESH:D012559 | Schizophrenia | Valproic Acid | 2.00 | 19110320 15737665 | |
| MESH:D012640 | Seizures | Phenobarbital | 8.13 | 16876388 11442880 4039156 3137016 | |
| MESH:D012640 | Seizures | Toluene | 8.13 | 9294310 6431079 | |
| MESH:D012640 | Seizures | Valproic Acid | 8.13 | 3137016 14763951 17978042 16876388 15475178 1511512 11738929 11044598 | |
| MESH:D003294 | Seizures, Febrile | Phenobarbital | 4.36 | 6407741 | |
| MESH:D012878 | Skin Neoplasms | Benzo(a)pyrene | 11.72 | 10029692 19755658 | |
| MESH:D012878 | Skin Neoplasms | Glucose | 11.72 | 14993021 | |
| MESH:D012878 | Skin Neoplasms | Iron | 11.72 | 12065085 | |
| MESH:D012878 | Skin Neoplasms | Tretinoin | 11.72 | 16467112 | |
| MESH:D013088 | Spermatocele | Tamoxifen | 3.82 | 16709447 | |
| MESH:D013119 | Spinal Cord Injuries | Tamoxifen | 3.57 | 19457130 | |
| MESH:D016135 | Spinal Dysraphism | Valproic Acid | 3.42 | 19490988 | |
| MESH:D013226 | Status Epilepticus | Valproic Acid | 4.07 | 12833885 | |
| MESH:D013272 | Stomach Diseases | Dexamethasone | 3.86 | 15472012 | |
| MESH:D013274 | Stomach Neoplasms | arsenic trioxide | 4.23 | 17007042 | |
| MESH:D013274 | Stomach Neoplasms | Benzo(a)pyrene | 4.23 | 20155912 2093021 | |
| MESH:D013274 | Stomach Neoplasms | Diethylnitrosamine | 4.23 | 18456281 | |
| MESH:D013274 | Stomach Neoplasms | Tretinoin | 4.23 | 17261132 | |
| MESH:D013276 | Stomach Ulcer | Dexamethasone | 3.09 | 15138204 | |
| MESH:D013398 | Sudden Infant Death | Iron | 4.98 | 16640825 | |
| MESH:D013733 | Testicular Diseases | Toluene | 4.49 | 10048760 10514026 | |
| MESH:D013964 | Thyroid Neoplasms | arsenic trioxide | 18.72 | 19014326 | |
| MESH:D013964 | Thyroid Neoplasms | Diethylnitrosamine | 18.72 | 7505956 | |
| MESH:D013964 | Thyroid Neoplasms | Phenobarbital | 18.72 | 1399818 | |
| MESH:D013964 | Thyroid Neoplasms | Tretinoin | 18.72 | 16026305 17045167 | |
| MESH:D013964 | Thyroid Neoplasms | triadimefon | 18.72 | 17178689 | |
| MESH:D014062 | Tongue Neoplasms | Tretinoin | 3.38 | 16051514 | |
| MESH:D016171 | Torsades de Pointes | arsenic trioxide | 3.50 | 15213294 | |
| MESH:D014178 | Translocation, Genetic | Valproic Acid | 4.76 | 17262798 | |
| MESH:D014376 | Tuberculosis | Iron | 7.18 | 16597321 | |
| MESH:D014376 | Tuberculosis | Tretinoin | 7.18 | 16040207 | |
| MESH:D020194 | Unverricht-Lundborg Syndrome | Valproic Acid | 4.06 | 3119515 | |
| MESH:D001749 | Urinary Bladder Neoplasms | arsenic trioxide | 7.12 | 12845720 20435036 11780464 12973940 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Benzo(a)pyrene | 7.12 | 17053015 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Tamoxifen | 7.12 | 17572228 16712894 8653321 | |
| MESH:D014564 | Urogenital Abnormalities | Valproic Acid | 4.19 | 8888407 | |
| MESH:D014581 | Urticaria | Acetaminophen | 2.55 | 10982225 | |
| MESH:D002583 | Uterine Cervical Neoplasms | Tretinoin | 3.27 | 16129372 | |
| MESH:D014604 | Uveal Neoplasms | Tretinoin | 4.14 | 16752155 | |
| MESH:D014605 | Uveitis | Cyclosporine | 10.19 | 1336536 | |
| MESH:D014605 | Uveitis | Dexamethasone | 10.19 | 1336536 | |
| MESH:D014820 | Vitiligo | Tretinoin | 3.61 | 16761959 | |
| MESH:D009396 | Wilms Tumor | Tretinoin | 3.57 | 16287080 | |
| MESH:D014985 | Xerophthalmia | Cyclosporine | 3.97 | 17120751 |
| Pathway ID | Pathway Name |
|---|---|
| KEGG:04973 | Carbohydrate digestion and absorption |
| REACT:474 | Metabolism of carbohydrates |
| REACT:15518 | Transmembrane transport of small molecules |