Annotation Detail for SLC5A5
Basic Information Top
| Gene Symbol: | SLC5A5 ( NIS,TDH1 ) |
|---|---|
| Gene Full Name: | solute carrier family 5 (sodium iodide symporter), member 5 |
| Band: | 19p13.11 |
| Quick Links | Entrez ID:6528; OMIM: 601843; Uniprot ID:SC5A5_HUMAN; ENSEMBL ID: ENSG00000105641; HGNC ID: 11040 |
| Relate to Another Database: | SFARIGene; denovo-db |
| No data |
| No data |
| Pathway ID | Pathway Name |
|---|---|
| Transmembrane transport of small molecules | |
| Amino acid and oligopeptide SLC transporters | |
| Hormone biosynthesis | |
| Metabolism of amino acids and derivatives |
| No data |
| No data |
| Pathway ID | Pathway Name |
|---|---|
| 500342 | Organic anion transporters |
| 500765 | Thyroxine biosynthesis |
| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| C085911 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Carbamazepine promotes the reaction [Tretinoin results in increased expression of SLC5A5 protein]] | decreases reaction|increases expression|increases reaction | 20300827 |
| C023035 | 3,4,5,3',4'-pentachlorobiphenyl | 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC5A5 mRNA | decreases expression | 16291828 |
| D000241 | Adenosine | Adenosine results in increased expression of SLC5A5 mRNA | increases expression | 16954431 |
| D000241 | Adenosine | Adenosine results in increased expression of SLC5A5 protein | increases expression | 16954431 |
| D000255 | Adenosine Triphosphate | Adenosine Triphosphate inhibits the reaction [TSHB protein results in increased expression of SLC5A5 protein] | decreases reaction|increases expression | 16439463 |
| C103303 | alitretinoin | alitretinoin results in increased expression of SLC5A5 mRNA | increases expression | 16954431 |
| D000638 | Amiodarone | Amiodarone results in decreased expression of SLC5A5 mRNA | decreases expression | 18020914 |
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of SLC5A5 mRNA | affects expression | 16483693 |
| D001374 | Azacitidine | [Azacitidine co-treated with Butyrates] affects the expression of SLC5A5 mRNA | affects cotreatment|affects expression | 17164311 |
| D001374 | Azacitidine | Azacitidine results in increased expression of SLC5A5 mRNA | increases expression | 16954431 |
| D015123 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of SLC5A5 mRNA | increases expression | 19150397 |
| D001959 | Bromates | SLC5A5 protein affects the transport of Bromates | affects transport | 16500013 |
| D001965 | Bromides | SLC5A5 protein affects the transport of Bromides | affects transport | 16500013 |
| C027561 | butylbenzyl phthalate | butylbenzyl phthalate results in increased expression of SLC5A5 mRNA | increases expression | 16257484 |
| C027561 | butylbenzyl phthalate | butylbenzyl phthalate results in increased expression of SLC5A5 mRNA | increases expression | 16257484 |
| D002087 | Butyrates | [Azacitidine co-treated with Butyrates] affects the expression of SLC5A5 mRNA | affects cotreatment|affects expression | 17164311 |
| D002087 | Butyrates | [Butyrates co-treated with decitabine] results in increased expression of SLC5A5 mRNA | affects cotreatment|increases expression | 17967635 |
| D002087 | Butyrates | [[Butyrates co-treated with decitabine] results in increased expression of SLC5A5 mRNA] which results in increased uptake of Iodine | affects cotreatment|increases expression|increases uptake | 17967635 |
| D002087 | Butyrates | Butyrates results in increased expression of SLC5A5 mRNA | increases expression | 17967635 |
| D002220 | Carbamazepine | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Carbamazepine promotes the reaction [Tretinoin results in increased expression of SLC5A5 protein]] | decreases reaction|increases expression|increases reaction | 20300827 |
| D002220 | Carbamazepine | Carbamazepine promotes the reaction [Tretinoin results in increased expression of SLC5A5 mRNA] | increases expression|increases reaction | 20300827 |
| D002220 | Carbamazepine | Carbamazepine promotes the reaction [Tretinoin results in increased expression of SLC5A5 protein] | increases expression|increases reaction | 20300827 |
| D002220 | Carbamazepine | wortmannin inhibits the reaction [Carbamazepine promotes the reaction [Tretinoin results in increased expression of SLC5A5 protein]] | decreases reaction|increases expression|increases reaction | 20300827 |
| D003513 | Cycloheximide | Cycloheximide results in increased expression of SLC5A5 mRNA | increases expression | 17164311 |
| C014347 | decitabine | [Butyrates co-treated with decitabine] results in increased expression of SLC5A5 mRNA | affects cotreatment|increases expression | 17967635 |
| C014347 | decitabine | [[Butyrates co-treated with decitabine] results in increased expression of SLC5A5 mRNA] which results in increased uptake of Iodine | affects cotreatment|increases expression|increases uptake | 17967635 |
| C014347 | decitabine | [decitabine co-treated with Tretinoin] results in increased expression of SLC5A5 mRNA | affects cotreatment|increases expression | 19524134 |
| C014347 | decitabine | decitabine results in increased expression of SLC5A5 mRNA | increases expression | 17967635 |
| D047630 | Depsipeptides | Depsipeptides results in increased expression of SLC5A5 mRNA | increases expression | 16954431 |
| D047630 | Depsipeptides | Depsipeptides results in increased expression of SLC5A5 protein | increases expression | 16954431 |
| D003907 | Dexamethasone | [Dexamethasone co-treated with Tretinoin] results in increased expression of SLC5A5 mRNA | affects cotreatment|increases expression | 16954431 |
| D003907 | Dexamethasone | Dexamethasone promotes the reaction [SLC5A5 protein results in increased uptake of Iodides] | increases reaction|increases uptake | 16234306 |
| D003907 | Dexamethasone | Dexamethasone promotes the reaction [Tretinoin results in increased expression of and results in increased activity of SLC5A5 protein] | increases activity|increases expression|increases reaction | 16234306 |
| D003907 | Dexamethasone | Dexamethasone promotes the reaction [Tretinoin results in increased expression of SLC5A5 mRNA] | increases expression|increases reaction | 16234306 |
| D003993 | Dibutyl Phthalate | Dibutyl Phthalate results in decreased expression of SLC5A5 mRNA | decreases expression | 16257484 |
| D003994 | Bucladesine | Bucladesine results in increased expression of SLC5A5 mRNA | increases expression | 16837620 |
| C042080 | diisodecyl phthalate | diisodecyl phthalate results in increased expression of SLC5A5 mRNA | increases expression | 16257484 |
| C042080 | diisodecyl phthalate | diisodecyl phthalate results in increased expression of SLC5A5 mRNA | increases expression | 16257484 |
| D017878 | 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid | 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid promotes the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide] | increases reaction|increases uptake | 12541134 |
| C010715 | di-n-octyl phthalate | di-n-octyl phthalate results in increased expression of SLC5A5 mRNA | increases expression | 16257484 |
| C010715 | di-n-octyl phthalate | di-n-octyl phthalate results in increased expression of SLC5A5 mRNA | increases expression | 16257484 |
| D004317 | Doxorubicin | SLC5A5 protein promotes the reaction [Doxorubicin results in increased uptake of Sodium Pertechnetate Tc 99m] | increases reaction|increases uptake | 15671536 |
| C063771 | dysidenin | dysidenin inhibits the reaction [SLC5A5 protein results in increased uptake of perrhenate analog] | decreases reaction|increases uptake | 12488351 |
| C063771 | dysidenin | dysidenin inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog] | decreases reaction|increases uptake | 12488351 |
| C063771 | dysidenin | dysidenin inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Pertechnetate Tc 99m] | decreases reaction|increases uptake | 12488351 |
| D015117 | 5,8,11,14-Eicosatetraynoic Acid | 5,8,11,14-Eicosatetraynoic Acid inhibits the reaction [TSHB protein results in increased expression of SLC5A5 mRNA] | decreases reaction|increases expression | 17962351 |
| D004958 | Estradiol | [Estradiol co-treated with OXT protein] results in increased expression of SLC5A5 mRNA | affects cotreatment|increases expression | 16954431 |
| D004958 | Estradiol | Estradiol results in increased expression of SLC5A5 protein | increases expression | 16954431 |
| D005031 | Ethylenethiourea | Ethylenethiourea results in increased expression of SLC5A5 mRNA | increases expression | 18801409 16837620 |
| D005576 | Forskolin | Forskolin inhibits the reaction [[Tretinoin co-treated with Hydrocortisone] results in increased activity of SLC5A5 protein] | affects cotreatment|decreases reaction|increases activity | 16439463 |
| D005576 | Forskolin | Forskolin results in increased expression of SLC5A5 mRNA | increases expression | 16954431 |
| D005576 | Forskolin | Forskolin results in increased expression of SLC5A5 protein | increases expression | 16954431 |
| D005576 | Forskolin | Forskolin results in increased expression of SLC5A5 mRNA | increases expression | 16954431 |
| D005576 | Forskolin | Forskolin results in increased expression of SLC5A5 protein | increases expression | 16954431 |
| D005576 | Forskolin | Forskolin results in increased expression of SLC5A5 mRNA | increases expression | 16837620 |
| D006854 | Hydrocortisone | 1-Methyl-3-isobutylxanthine promotes the reaction [[Tretinoin co-treated with Hydrocortisone] affects the localization of SLC5A5 protein] | affects cotreatment|affects localization|increases reaction | 16439463 |
| D006854 | Hydrocortisone | 1-Methyl-3-isobutylxanthine promotes the reaction [[Tretinoin co-treated with Hydrocortisone] results in increased expression of SLC5A5 protein] | affects cotreatment|increases expression|increases reaction | 16439463 |
| D006854 | Hydrocortisone | Forskolin inhibits the reaction [[Tretinoin co-treated with Hydrocortisone] results in increased activity of SLC5A5 protein] | affects cotreatment|decreases reaction|increases activity | 16439463 |
| D006854 | Hydrocortisone | Hydrocortisone promotes the reaction [Tretinoin affects the localization of SLC5A5 protein] | affects localization|increases reaction | 16439463 |
| D006854 | Hydrocortisone | Hydrocortisone promotes the reaction [Tretinoin results in increased expression of SLC5A5 protein] | increases expression|increases reaction | 16439463 |
| D007454 | Iodides | Dexamethasone promotes the reaction [SLC5A5 protein results in increased uptake of Iodides] | increases reaction|increases uptake | 16234306 |
| D007454 | Iodides | perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Iodides] | decreases reaction|increases uptake | 15941870 15850642 |
| D007454 | Iodides | potassium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Iodides] | decreases reaction|increases uptake | 15671536 |
| D007454 | Iodides | SLC5A5 protein results in increased uptake of Iodides | increases uptake | 15941870 15671536 15850642 16234306 |
| D007454 | Iodides | thiocyanate inhibits the reaction [SLC5A5 protein results in increased uptake of Iodides] | decreases reaction|increases uptake | 15850642 |
| D007454 | Iodides | perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Iodides] | decreases reaction|increases uptake | 16500013 |
| D007454 | Iodides | SLC5A5 protein affects the transport of Iodides | affects transport | 16500013 |
| D007455 | Iodine | [[Butyrates co-treated with decitabine] results in increased expression of SLC5A5 mRNA] which results in increased uptake of Iodine | affects cotreatment|increases expression|increases uptake | 17967635 |
| D007455 | Iodine | SLC5A5 protein affects the transport of Iodine | affects transport | 12602914 |
| D007455 | Iodine | SLC5A5 protein results in increased uptake of Iodine | increases uptake | 17332617 |
| D007455 | Iodine | SLC5A5 protein results in increased uptake of Iodine | increases uptake | 17408651 |
| D015056 | 1-Methyl-3-isobutylxanthine | 1-Methyl-3-isobutylxanthine promotes the reaction [[Tretinoin co-treated with Hydrocortisone] affects the localization of SLC5A5 protein] | affects cotreatment|affects localization|increases reaction | 16439463 |
| D015056 | 1-Methyl-3-isobutylxanthine | 1-Methyl-3-isobutylxanthine promotes the reaction [[Tretinoin co-treated with Hydrocortisone] results in increased expression of SLC5A5 protein] | affects cotreatment|increases expression|increases reaction | 16439463 |
| D008713 | Methimazole | Methimazole results in increased expression of SLC5A5 protein | increases expression | 17332529 |
| C100075 | mibolerone | mibolerone promotes the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide] | increases reaction|increases uptake | 14633711 |
| C100075 | mibolerone | perchlorate inhibits the reaction [mibolerone promotes the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]] | decreases reaction|increases reaction|increases uptake | 14633711 |
| D009637 | Nordihydroguaiaretic Acid | Nordihydroguaiaretic Acid inhibits the reaction [TSHB protein results in increased expression of SLC5A5 mRNA] | decreases reaction|increases expression | 17962351 |
| C494474 | perchlorate | perchlorate inhibits the reaction [mibolerone promotes the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]] | decreases reaction|increases reaction|increases uptake | 14633711 |
| C494474 | perchlorate | perchlorate inhibits the reaction [SLC5A5 protein results in increased abundance of Sodium Iodide] | decreases reaction|increases abundance | 15347726 |
| C494474 | perchlorate | perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Iodides] | decreases reaction|increases uptake | 15941870 15850642 |
| C494474 | perchlorate | perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide] | decreases reaction|increases uptake | 12601449 |
| C494474 | perchlorate | perchlorate results in increased expression of SLC5A5 protein | increases expression | 17332529 |
| C494474 | perchlorate | perchlorate results in decreased activity of SLC5A5 protein | decreases activity | 16987991 |
| C494474 | perchlorate | perchlorate results in increased expression of SLC5A5 mRNA | increases expression | 18801409 |
| C494474 | perchlorate | perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Iodides] | decreases reaction|increases uptake | 16500013 |
| C494474 | perchlorate | SLC5A5 protein affects the transport of perchlorate | affects transport | 16500013 |
| C015428 | perrhenate | dysidenin inhibits the reaction [SLC5A5 protein results in increased uptake of perrhenate analog] | decreases reaction|increases uptake | 12488351 |
| C015428 | perrhenate | perrhenate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog] | decreases reaction|increases uptake | 12488351 |
| C015428 | perrhenate | perrhenate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Pertechnetate Tc 99m] | decreases reaction|increases uptake | 12488351 |
| C015428 | perrhenate | SLC5A5 protein results in increased uptake of perrhenate | increases uptake | 15347726 |
| C015428 | perrhenate | SLC5A5 protein results in increased uptake of perrhenate analog | increases uptake | 12488351 |
| C015428 | perrhenate | sodium bromide inhibits the reaction [SLC5A5 protein results in increased uptake of perrhenate analog] | decreases reaction|increases uptake | 12488351 |
| C015428 | perrhenate | sodium chlorate inhibits the reaction [SLC5A5 protein results in increased uptake of perrhenate analog] | decreases reaction|increases uptake | 12488351 |
| C015428 | perrhenate | Sodium Iodide inhibits the reaction [SLC5A5 protein results in increased uptake of perrhenate analog] | decreases reaction|increases uptake | 12488351 |
| C015428 | perrhenate | sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of perrhenate analog] | decreases reaction|increases uptake | 12488351 |
| C015428 | perrhenate | sodium thiocyanate inhibits the reaction [SLC5A5 protein results in increased uptake of perrhenate analog] | decreases reaction|increases uptake | 12488351 |
| C009006 | potassium perchlorate | potassium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Iodides] | decreases reaction|increases uptake | 15671536 |
| C009006 | potassium perchlorate | potassium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide] | decreases reaction|increases uptake | 15522214 17611400 |
| C009006 | potassium perchlorate | potassium perchlorate results in decreased activity of SLC5A5 protein | decreases activity | 17611400 |
| D011794 | Quercetin | Quercetin inhibits the reaction [TSHB protein results in increased expression of SLC5A5 mRNA] | decreases reaction|increases expression | 17962351 |
| C027938 | sodium bromide | sodium bromide inhibits the reaction [SLC5A5 protein results in increased uptake of perrhenate analog] | decreases reaction|increases uptake | 12488351 |
| C027938 | sodium bromide | sodium bromide inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog] | decreases reaction|increases uptake | 12488351 |
| C027938 | sodium bromide | sodium bromide inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Pertechnetate Tc 99m] | decreases reaction|increases uptake | 12488351 |
| C032706 | sodium chlorate | sodium chlorate inhibits the reaction [SLC5A5 protein results in increased uptake of perrhenate analog] | decreases reaction|increases uptake | 12488351 |
| C032706 | sodium chlorate | sodium chlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog] | decreases reaction|increases uptake | 12488351 |
| C032706 | sodium chlorate | sodium chlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Pertechnetate Tc 99m] | decreases reaction|increases uptake | 12488351 |
| D012974 | Sodium Iodide | 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid promotes the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide] | increases reaction|increases uptake | 12541134 |
| D012974 | Sodium Iodide | dysidenin inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog] | decreases reaction|increases uptake | 12488351 |
| D012974 | Sodium Iodide | mibolerone promotes the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide] | increases reaction|increases uptake | 14633711 |
| D012974 | Sodium Iodide | Ouabain inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide] | decreases reaction|increases uptake | 12541134 |
| D012974 | Sodium Iodide | perchlorate inhibits the reaction [mibolerone promotes the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]] | decreases reaction|increases reaction|increases uptake | 14633711 |
| D012974 | Sodium Iodide | perchlorate inhibits the reaction [SLC5A5 protein results in increased abundance of Sodium Iodide] | decreases reaction|increases abundance | 15347726 |
| D012974 | Sodium Iodide | perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide] | decreases reaction|increases uptake | 12601449 |
| D012974 | Sodium Iodide | perrhenate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog] | decreases reaction|increases uptake | 12488351 |
| D012974 | Sodium Iodide | potassium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide] | decreases reaction|increases uptake | 17611400 15522214 |
| D012974 | Sodium Iodide | SLC5A5 protein results in decreased export of Sodium Iodide | decreases export | 15522214 15347726 |
| D012974 | Sodium Iodide | SLC5A5 protein results in increased abundance of Sodium Iodide | increases abundance | 15347726 |
| D012974 | Sodium Iodide | SLC5A5 protein results in increased uptake of Sodium Iodide | increases uptake | 12541134 12489024 17611400 15522214 12488351 14633711 12601449 |
| D012974 | Sodium Iodide | sodium bromide inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog] | decreases reaction|increases uptake | 12488351 |
| D012974 | Sodium Iodide | sodium chlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog] | decreases reaction|increases uptake | 12488351 |
| D012974 | Sodium Iodide | Sodium Iodide inhibits the reaction [SLC5A5 protein results in increased uptake of perrhenate analog] | decreases reaction|increases uptake | 12488351 |
| D012974 | Sodium Iodide | Sodium Iodide inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Pertechnetate Tc 99m] | decreases reaction|increases uptake | 12488351 |
| D012974 | Sodium Iodide | sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide] | decreases reaction|increases uptake | 12489024 12541134 |
| D012974 | Sodium Iodide | sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog] | decreases reaction|increases uptake | 12488351 |
| D012974 | Sodium Iodide | sodium thiocyanate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog] | decreases reaction|increases uptake | 12488351 |
| D012974 | Sodium Iodide | SLC5A5 protein results in increased uptake of Sodium Iodide | increases uptake | 15520214 12489024 |
| D012974 | Sodium Iodide | Sodium Iodide results in increased activity of SLC5A5 protein | increases activity | 16987991 |
| D012974 | Sodium Iodide | sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide] | decreases reaction|increases uptake | 12489024 15520214 |
| D012974 | Sodium Iodide | SLC5A5 protein alternative form results in increased uptake of Sodium Iodide | increases uptake | 12586784 |
| D012974 | Sodium Iodide | SLC5A5 protein results in increased uptake of Sodium Iodide | increases uptake | 12586784 |
| D012974 | Sodium Iodide | sodium perchlorate inhibits the reaction [SLC5A5 protein alternative form results in increased uptake of Sodium Iodide] | decreases reaction|increases uptake | 12586784 |
| D012974 | Sodium Iodide | sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide] | decreases reaction|increases uptake | 12586784 |
| C031068 | sodium perchlorate | sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of perrhenate analog] | decreases reaction|increases uptake | 12488351 |
| C031068 | sodium perchlorate | sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide] | decreases reaction|increases uptake | 12489024 12541134 |
| C031068 | sodium perchlorate | sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog] | decreases reaction|increases uptake | 12488351 |
| C031068 | sodium perchlorate | sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Pertechnetate Tc 99m] | decreases reaction|increases uptake | 12488351 |
| C031068 | sodium perchlorate | sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Technetium] | decreases reaction|increases uptake | 15221289 |
| C031068 | sodium perchlorate | sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide] | decreases reaction|increases uptake | 15520214 12489024 |
| C031068 | sodium perchlorate | sodium perchlorate inhibits the reaction [SLC5A5 protein alternative form results in increased uptake of Sodium Iodide] | decreases reaction|increases uptake | 12586784 |
| C031068 | sodium perchlorate | sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide] | decreases reaction|increases uptake | 12586784 |
| C031068 | sodium perchlorate | sodium perchlorate results in increased expression of SLC5A5 mRNA | increases expression | 16837620 |
| C024553 | sodium thiocyanate | sodium thiocyanate inhibits the reaction [SLC5A5 protein results in increased uptake of perrhenate analog] | decreases reaction|increases uptake | 12488351 |
| C024553 | sodium thiocyanate | sodium thiocyanate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog] | decreases reaction|increases uptake | 12488351 |
| C024553 | sodium thiocyanate | sodium thiocyanate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Pertechnetate Tc 99m] | decreases reaction|increases uptake | 12488351 |
| D010042 | Ouabain | Ouabain inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide] | decreases reaction|increases uptake | 12541134 |
| D013974 | Thyroxine | Thyroxine results in decreased expression of SLC5A5 protein | decreases expression | 17332529 |
| C086827 | tazarotene | tazarotene results in increased expression of SLC5A5 mRNA | increases expression | 16954431 |
| D013670 | Sodium Pertechnetate Tc 99m | dysidenin inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Pertechnetate Tc 99m] | decreases reaction|increases uptake | 12488351 |
| D013670 | Sodium Pertechnetate Tc 99m | perrhenate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Pertechnetate Tc 99m] | decreases reaction|increases uptake | 12488351 |
| D013670 | Sodium Pertechnetate Tc 99m | SLC5A5 protein promotes the reaction [Doxorubicin results in increased uptake of Sodium Pertechnetate Tc 99m] | increases reaction|increases uptake | 15671536 |
| D013670 | Sodium Pertechnetate Tc 99m | SLC5A5 protein results in increased uptake of Sodium Pertechnetate Tc 99m | increases uptake | 15347726 12488351 12602914 |
| D013670 | Sodium Pertechnetate Tc 99m | sodium bromide inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Pertechnetate Tc 99m] | decreases reaction|increases uptake | 12488351 |
| D013670 | Sodium Pertechnetate Tc 99m | sodium chlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Pertechnetate Tc 99m] | decreases reaction|increases uptake | 12488351 |
| D013670 | Sodium Pertechnetate Tc 99m | Sodium Iodide inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Pertechnetate Tc 99m] | decreases reaction|increases uptake | 12488351 |
| D013670 | Sodium Pertechnetate Tc 99m | sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Pertechnetate Tc 99m] | decreases reaction|increases uptake | 12488351 |
| D013670 | Sodium Pertechnetate Tc 99m | sodium thiocyanate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Pertechnetate Tc 99m] | decreases reaction|increases uptake | 12488351 |
| D013667 | Technetium | SLC5A5 protein results in increased uptake of Technetium | increases uptake | 15221289 |
| D013667 | Technetium | sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Technetium] | decreases reaction|increases uptake | 15221289 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in decreased expression of SLC5A5 mRNA | decreases expression | 16291828 |
| C031760 | thiocyanate | SLC5A5 protein affects the transport of thiocyanate | affects transport | 15345749 |
| C031760 | thiocyanate | thiocyanate inhibits the reaction [SLC5A5 protein results in increased uptake of Iodides] | decreases reaction|increases uptake | 15850642 |
| D014212 | Tretinoin | 1-Methyl-3-isobutylxanthine promotes the reaction [[Tretinoin co-treated with Hydrocortisone] affects the localization of SLC5A5 protein] | affects cotreatment|affects localization|increases reaction | 16439463 |
| D014212 | Tretinoin | 1-Methyl-3-isobutylxanthine promotes the reaction [[Tretinoin co-treated with Hydrocortisone] results in increased expression of SLC5A5 protein] | affects cotreatment|increases expression|increases reaction | 16439463 |
| D014212 | Tretinoin | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Carbamazepine promotes the reaction [Tretinoin results in increased expression of SLC5A5 protein]] | decreases reaction|increases expression|increases reaction | 20300827 |
| D014212 | Tretinoin | Carbamazepine promotes the reaction [Tretinoin results in increased expression of SLC5A5 mRNA] | increases expression|increases reaction | 20300827 |
| D014212 | Tretinoin | Carbamazepine promotes the reaction [Tretinoin results in increased expression of SLC5A5 protein] | increases expression|increases reaction | 20300827 |
| D014212 | Tretinoin | [decitabine co-treated with Tretinoin] results in increased expression of SLC5A5 mRNA | affects cotreatment|increases expression | 19524134 |
| D014212 | Tretinoin | [Dexamethasone co-treated with Tretinoin] results in increased expression of SLC5A5 mRNA | affects cotreatment|increases expression | 16954431 |
| D014212 | Tretinoin | Dexamethasone promotes the reaction [Tretinoin results in increased expression of and results in increased activity of SLC5A5 protein] | increases activity|increases expression|increases reaction | 16234306 |
| D014212 | Tretinoin | Dexamethasone promotes the reaction [Tretinoin results in increased expression of SLC5A5 mRNA] | increases expression|increases reaction | 16234306 |
| D014212 | Tretinoin | ESR1 protein promotes the reaction [Tretinoin results in increased expression of SLC5A5 protein] | increases expression|increases reaction | 16730657 |
| D014212 | Tretinoin | Forskolin inhibits the reaction [[Tretinoin co-treated with Hydrocortisone] results in increased activity of SLC5A5 protein] | affects cotreatment|decreases reaction|increases activity | 16439463 |
| D014212 | Tretinoin | Hydrocortisone promotes the reaction [Tretinoin affects the localization of SLC5A5 protein] | affects localization|increases reaction | 16439463 |
| D014212 | Tretinoin | Hydrocortisone promotes the reaction [Tretinoin results in increased expression of SLC5A5 protein] | increases expression|increases reaction | 16439463 |
| D014212 | Tretinoin | Tretinoin affects the localization of SLC5A5 protein | affects localization | 16439463 |
| D014212 | Tretinoin | Tretinoin inhibits the reaction [TSHB protein results in increased expression of SLC5A5 protein] | decreases reaction|increases expression | 16439463 |
| D014212 | Tretinoin | Tretinoin results in increased expression of and results in increased activity of SLC5A5 protein | increases activity|increases expression | 16234306 |
| D014212 | Tretinoin | Tretinoin results in increased expression of SLC5A5 mRNA | increases expression | 20300827 16234306 17332617 17045167 16954431 |
| D014212 | Tretinoin | Tretinoin results in increased expression of SLC5A5 protein | increases expression | 20300827 16439463 |
| D014212 | Tretinoin | [troglitazone co-treated with Tretinoin] results in increased expression of SLC5A5 mRNA | affects cotreatment|increases expression | 16954431 |
| D014212 | Tretinoin | wortmannin inhibits the reaction [Carbamazepine promotes the reaction [Tretinoin results in increased expression of SLC5A5 protein]] | decreases reaction|increases expression|increases reaction | 20300827 |
| C012589 | trichostatin A | trichostatin A results in increased expression of SLC5A5 mRNA | increases expression | 16954431 |
| C012589 | trichostatin A | trichostatin A results in increased expression of SLC5A5 protein | increases expression | 16954431 |
| C057693 | troglitazone | [troglitazone co-treated with Tretinoin] results in increased expression of SLC5A5 mRNA | affects cotreatment|increases expression | 16954431 |
| C057693 | troglitazone | troglitazone results in increased expression of SLC5A5 mRNA | increases expression | 16954431 |
| D014635 | Valproic Acid | Valproic Acid results in increased expression of SLC5A5 mRNA | increases expression | 16954431 |
| D014635 | Valproic Acid | Valproic Acid results in increased expression of SLC5A5 protein | increases expression | 16954431 |
| C009687 | wortmannin | wortmannin inhibits the reaction [Carbamazepine promotes the reaction [Tretinoin results in increased expression of SLC5A5 protein]] | decreases reaction|increases expression|increases reaction | 20300827 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000014 | Abnormalities, Drug-Induced | Carbamazepine | 10.95 | 8986270 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Tetrachlorodibenzodioxin | 10.95 | 11752688 15322242 14514962 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Valproic Acid | 10.95 | 8875741 | |
| MESH:D000015 | Abnormalities, Multiple | Valproic Acid | 3.40 | 19490988 | |
| MESH:D000138 | Acidosis | Ammonium Chloride | 2.97 | 18287403 | |
| MESH:D000230 | Adenocarcinoma | Doxorubicin | 6.24 | 17418594 | |
| MESH:D000230 | Adenocarcinoma | Estradiol | 6.24 | 11473722 | |
| MESH:D000230 | Adenocarcinoma | Ethylenethiourea | 6.24 | 7955072 | |
| MESH:D018248 | Adenoma, Liver Cell | 3,4,5,3',4'-pentachlorobiphenyl | 8.58 | 16628245 | |
| MESH:D018248 | Adenoma, Liver Cell | Tetrachlorodibenzodioxin | 8.58 | 16835633 | |
| MESH:D000419 | Albuminuria | Doxorubicin | 3.98 | 21441931 | |
| MESH:D000505 | Alopecia | Tretinoin | 3.14 | 15955085 | |
| MESH:D000550 | Amblyopia | Valproic Acid | 4.63 | 17688650 | |
| MESH:D000740 | Anemia | Tetrachlorodibenzodioxin | 2.43 | 11748828 | |
| MESH:D000743 | Anemia, Hemolytic | Quercetin | 3.71 | 17084956 | |
| MESH:D001008 | Anxiety Disorders | Valproic Acid | 3.10 | 17497229 | |
| MESH:D001145 | Arrhythmias, Cardiac | Amiodarone | 3.29 | 18057881 18218290 20041841 | |
| MESH:D001169 | Arthritis, Experimental | Dexamethasone | 6.23 | 17659584 | |
| MESH:D001169 | Arthritis, Experimental | Tretinoin | 6.23 | 16412693 | |
| MESH:D001172 | Arthritis, Rheumatoid | Tretinoin | 2.10 | 16292516 | |
| MESH:D001249 | Asthma | Tretinoin | 2.14 | 16456186 | |
| MESH:D001260 | Ataxia Telangiectasia | Quercetin | 4.38 | 15336622 | |
| MESH:D001281 | Atrial Fibrillation | Amiodarone | 3.45 | 19698954 18651412 | |
| MESH:D001321 | Autistic Disorder | Adenosine | 2.77 | 20468076 | |
| MESH:D001321 | Autistic Disorder | Valproic Acid | 2.77 | 18940202 17157402 15238991 19232924 18985861 19460635 16609825 17688650 18177632 18558336 18775368 18316065 17507914 20603192 18396377 | |
| MESH:D001327 | Autoimmune Diseases | Quercetin | 3.83 | 19761891 | |
| MESH:D001471 | Barrett Esophagus | Tretinoin | 3.84 | 16935849 | |
| MESH:D001714 | Bipolar Disorder | Carbamazepine | 6.44 | 20046352 17594078 | |
| MESH:D001714 | Bipolar Disorder | Valproic Acid | 6.44 | 17594078 20046352 | |
| MESH:D001778 | Blood Coagulation Disorders | Amiodarone | 12.30 | 19483382 | |
| MESH:D001778 | Blood Coagulation Disorders | Tetrachlorodibenzodioxin | 12.30 | 12125929 | |
| MESH:D001778 | Blood Coagulation Disorders | Tretinoin | 12.30 | 16206674 16197459 | |
| MESH:D001836 | Body Weight Changes | Tetrachlorodibenzodioxin | 3.19 | 15340226 | |
| MESH:D001848 | Bone Diseases, Developmental | Tetrachlorodibenzodioxin | 6.68 | 15746008 | |
| MESH:D001848 | Bone Diseases, Developmental | Valproic Acid | 6.68 | 8888407 | |
| MESH:D019046 | Bone Marrow Neoplasms | Doxorubicin | 4.10 | 14601052 | |
| MESH:D001932 | Brain Neoplasms | Doxorubicin | 3.30 | 17150277 | |
| MESH:D001943 | Breast Neoplasms | therapeutic | 12489024 | ||
| MESH:D001943 | Breast Neoplasms | alitretinoin | 4.07 | 16344269 | |
| MESH:D001943 | Breast Neoplasms | decitabine | 4.07 | 19208741 18320071 | |
| MESH:D001943 | Breast Neoplasms | Doxorubicin | 4.07 | 15939500 17369602 15567936 15634643 19526202 18382427 15136595 15993339 18695136 16115903 16264153 15668708 17426702 16595493 16935488 16826403 17983394 18234424 16322301 15692762 16096432 11325840 18628466 15994142 | |
| MESH:D001943 | Breast Neoplasms | Estradiol | 4.07 | 12948864 19861407 17261762 17289903 18497071 16675129 14630087 17018787 | |
| MESH:D001943 | Breast Neoplasms | Nordihydroguaiaretic Acid | 4.07 | 18418215 | |
| MESH:D001943 | Breast Neoplasms | Quercetin | 4.07 | 18628248 | |
| MESH:D001943 | Breast Neoplasms | Tetrachlorodibenzodioxin | 4.07 | 20435547 | |
| MESH:D001943 | Breast Neoplasms | Tretinoin | 4.07 | 16166294 16443354 16873071 | |
| MESH:D001997 | Bronchopulmonary Dysplasia | Tretinoin | 4.00 | 16813970 | |
| MESH:D002105 | Cadmium Poisoning | Quercetin | 4.94 | 16962696 | |
| MESH:D002181 | Candidiasis, Vulvovaginal | Estradiol | 3.87 | 16111702 | |
| MESH:D002276 | Carcinoid Tumor | Doxorubicin | 4.21 | 16051944 | |
| MESH:D002277 | Carcinoma | Tetrachlorodibenzodioxin | 2.33 | 16835633 | |
| MESH:D018236 | Carcinoma, Embryonal | Tretinoin | 4.55 | 16168501 | |
| MESH:D006528 | Carcinoma, Hepatocellular | therapeutic | 15347726 15520214 | ||
| MESH:D006528 | Carcinoma, Hepatocellular | Doxorubicin | 5.57 | 16234567 18059187 17876044 16023760 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Estradiol | 5.57 | 16924424 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Quercetin | 5.57 | 19519916 12508355 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Tretinoin | 5.57 | 1917145 | |
| MESH:D021441 | Carcinoma, Pancreatic Ductal | Quercetin | 4.38 | 17234771 | |
| MESH:D002292 | Carcinoma, Renal Cell | Doxorubicin | 2.85 | 1485588 16201981 | |
| MESH:D002294 | Carcinoma, Squamous Cell | decitabine | 6.36 | 19215824 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Doxorubicin | 6.36 | 6189445 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Tretinoin | 6.36 | 16096774 16051514 | |
| MESH:D006332 | Cardiomegaly | Quercetin | 9.47 | 19794523 | |
| MESH:D006332 | Cardiomegaly | Tetrachlorodibenzodioxin | 9.47 | 16120746 18850075 18670907 | |
| MESH:D006332 | Cardiomegaly | Thyroxine | 9.47 | 18093424 | |
| MESH:D009202 | Cardiomyopathies | Doxorubicin | 3.12 | 17519947 16278810 17131338 16269455 16612575 17351982 17924179 17308081 16364871 15792986 16455267 16731534 16242529 17928571 17007740 17382496 17329180 18627295 16651473 17974986 15476868 15811867 16109756 15505089 16952015 | |
| MESH:D002311 | Cardiomyopathy, Dilated | Amiodarone | 5.17 | 15710769 19225199 | |
| MESH:D002311 | Cardiomyopathy, Dilated | Doxorubicin | 5.17 | 16243910 17334414 | |
| MESH:D002341 | Carotid Artery Thrombosis | Amiodarone | 4.49 | 18974383 | |
| MESH:D002386 | Cataract | Adenosine Triphosphate | 6.72 | 15003327 | |
| MESH:D002386 | Cataract | Tretinoin | 6.72 | 17460283 | |
| MESH:D002471 | Cell Transformation, Neoplastic | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | 5.24 | 20889678 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Estradiol | 5.24 | 18566989 | |
| MESH:D018290 | Cervical Intraepithelial Neoplasia | Tretinoin | 4.00 | 16129372 | |
| MESH:D002659 | Child Development Disorders, Pervasive | Valproic Acid | 2.46 | 20734317 | |
| MESH:D018281 | Cholangiocarcinoma | marker/mechanism | 17408651 | ||
| MESH:D018281 | Cholangiocarcinoma | 3,4,5,3',4'-pentachlorobiphenyl | 8.14 | 16628245 | |
| MESH:D018281 | Cholangiocarcinoma | Tetrachlorodibenzodioxin | 8.14 | 16835633 | |
| MESH:D002822 | Choriocarcinoma | Tretinoin | 4.55 | 16461808 | |
| MESH:D002972 | Cleft Palate | Hydrocortisone | 8.31 | 15826874 | |
| MESH:D002972 | Cleft Palate | Tetrachlorodibenzodioxin | 8.31 | 15668235 16354765 12621046 8697196 15340226 | |
| MESH:D002972 | Cleft Palate | Tretinoin | 8.31 | 9407595 | |
| MESH:D003092 | Colitis | Tretinoin | 3.13 | 17035595 | |
| MESH:D003110 | Colonic Neoplasms | Butyrates | 9.52 | 15936596 | |
| MESH:D003110 | Colonic Neoplasms | decitabine | 9.52 | 17616700 | |
| MESH:D003110 | Colonic Neoplasms | Dexamethasone | 9.52 | 15824018 | |
| MESH:D003110 | Colonic Neoplasms | Nordihydroguaiaretic Acid | 9.52 | 15936596 | |
| MESH:D003110 | Colonic Neoplasms | Quercetin | 9.52 | 17191121 15741050 19056647 17148506 19440933 11134977 16640504 | |
| MESH:D015179 | Colorectal Neoplasms | Azacitidine | 4.22 | 19934284 | |
| MESH:D015179 | Colorectal Neoplasms | decitabine | 4.22 | 18981723 | |
| MESH:D015179 | Colorectal Neoplasms | Doxorubicin | 4.22 | 18259882 18802399 | |
| MESH:D015179 | Colorectal Neoplasms | Quercetin | 4.22 | 18095365 18852136 | |
| MESH:D000013 | Congenital Abnormalities | Tetrachlorodibenzodioxin | 2.56 | 17141729 14669216 | |
| MESH:D019465 | Craniofacial Abnormalities | 3,4,5,3',4'-pentachlorobiphenyl | 10.35 | 17686920 | |
| MESH:D019465 | Craniofacial Abnormalities | Carbamazepine | 10.35 | 9014606 | |
| MESH:D019465 | Craniofacial Abnormalities | Dexamethasone | 10.35 | 17728286 | |
| MESH:D019465 | Craniofacial Abnormalities | Hydrocortisone | 10.35 | 17728286 | |
| MESH:D019465 | Craniofacial Abnormalities | Tetrachlorodibenzodioxin | 10.35 | 20055451 10048152 15322242 | |
| MESH:D019465 | Craniofacial Abnormalities | Tretinoin | 10.35 | 16925845 8800419 9142499 9224671 9211117 14991402 9664655 10589399 9125849 17551590 | |
| MESH:D019465 | Craniofacial Abnormalities | Valproic Acid | 10.35 | 17688650 16575769 8888407 | |
| MESH:D003456 | Cryptorchidism | Dibutyl Phthalate | 4.88 | 16037377 | |
| MESH:D017449 | Dermatitis, Allergic Contact | Dexamethasone | 2.87 | 12438553 | |
| MESH:D003921 | Diabetes Mellitus, Experimental | Quercetin | 3.25 | 19496084 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Tetrachlorodibenzodioxin | 4.11 | 17107852 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | troglitazone | 4.11 | 16023994 | |
| MESH:D003925 | Diabetic Angiopathies | troglitazone | 5.06 | 12601628 | |
| MESH:D003928 | Diabetic Nephropathies | Estradiol | 2.91 | 19279558 | |
| MESH:D003967 | Diarrhea | Dexamethasone | 6.77 | 7237001 | |
| MESH:D003967 | Diarrhea | Hydrocortisone | 6.77 | 7237001 | |
| OMIM:607208 | DRAVET SYNDROME | Carbamazepine | 4.87 | 11748493 | |
| MESH:D004342 | Drug Hypersensitivity | Carbamazepine | 4.02 | 20216337 16538176 15057820 16538175 | |
| MESH:D056486 | Drug-Induced Liver Injury | Amiodarone | 12.41 | 18218290 15265979 | |
| MESH:D056486 | Drug-Induced Liver Injury | Carbamazepine | 12.41 | 17465707 | |
| MESH:D056486 | Drug-Induced Liver Injury | Doxorubicin | 12.41 | 17416283 | |
| MESH:D056486 | Drug-Induced Liver Injury | Tetrachlorodibenzodioxin | 12.41 | 20420201 | |
| MESH:D056486 | Drug-Induced Liver Injury | troglitazone | 12.41 | 14986274 | |
| MESH:D056486 | Drug-Induced Liver Injury | Valproic Acid | 12.41 | 19641884 1733752 | |
| MESH:D004362 | Drug Toxicity | Carbamazepine | 11.24 | 20216337 | |
| MESH:D004362 | Drug Toxicity | Doxorubicin | 11.24 | 18602426 | |
| MESH:D004362 | Drug Toxicity | Tetrachlorodibenzodioxin | 11.24 | 11462148 | |
| MESH:D004421 | Dystonia | Valproic Acid | 3.50 | 1851702 | |
| MESH:D004485 | Eczema | Dexamethasone | 3.90 | 12438553 | |
| MESH:D004487 | Edema | Dexamethasone | 5.16 | 19703484 | |
| MESH:D004487 | Edema | Tetrachlorodibenzodioxin | 5.16 | 11000095 12711302 | |
| MESH:D004489 | Edema, Cardiac | 3,4,5,3',4'-pentachlorobiphenyl | 17.61 | 17686920 | |
| MESH:D004489 | Edema, Cardiac | Tetrachlorodibenzodioxin | 17.61 | 18230668 16714409 15322242 | |
| MESH:D004489 | Edema, Cardiac | Tretinoin | 17.61 | 18230668 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Carbamazepine | 4.18 | 17654737 | |
| MESH:D004701 | Endocrine Gland Neoplasms | decitabine | 12.02 | 19294695 | |
| MESH:D004701 | Endocrine Gland Neoplasms | trichostatin A | 12.02 | 19294695 | |
| MESH:D016889 | Endometrial Neoplasms | Doxorubicin | 14.52 | 17359293 | |
| MESH:D016889 | Endometrial Neoplasms | Estradiol | 14.52 | 18566989 11473722 19148513 | |
| MESH:D016889 | Endometrial Neoplasms | Ethylenethiourea | 14.52 | 7955072 | |
| MESH:D016889 | Endometrial Neoplasms | Tretinoin | 14.52 | 16569247 | |
| MESH:D004715 | Endometriosis | Tetrachlorodibenzodioxin | 2.51 | 9294722 10568697 | |
| MESH:D004719 | Endomyocardial Fibrosis | Doxorubicin | 4.55 | 18037988 | |
| MESH:D004816 | Epidermal Necrolysis, Toxic | Carbamazepine | 4.69 | 19915237 16538176 20485159 16415921 18855540 | |
| MESH:D004831 | Epilepsies, Myoclonic | Carbamazepine | 9.28 | 17275665 | |
| MESH:D004831 | Epilepsies, Myoclonic | Valproic Acid | 9.28 | 17275665 3659116 | |
| MESH:D004828 | Epilepsies, Partial | Carbamazepine | 8.38 | 16628512 17116037 15008574 | |
| MESH:D004828 | Epilepsies, Partial | Valproic Acid | 8.38 | 3922381 16628512 | |
| MESH:D004827 | Epilepsy | Adenosine | 9.46 | 11404469 | |
| MESH:D004827 | Epilepsy | Carbamazepine | 9.46 | 7988514 9014606 18234410 17178248 17465707 19700373 19439326 821787 19620853 20417680 | |
| MESH:D004827 | Epilepsy | Valproic Acid | 9.46 | 18234410 20417680 | |
| MESH:D004832 | Epilepsy, Absence | Valproic Acid | 3.09 | 6426943 6254150 7562514 | |
| MESH:D017029 | Epilepsy, Complex Partial | Carbamazepine | 9.79 | 7750514 | |
| MESH:D017029 | Epilepsy, Complex Partial | Valproic Acid | 9.79 | 7750514 | |
| MESH:D004830 | Epilepsy, Tonic-Clonic | Carbamazepine | 8.92 | 15276670 3659116 | |
| MESH:D004830 | Epilepsy, Tonic-Clonic | Valproic Acid | 8.92 | 3659116 | |
| MESH:D004916 | Erythromelalgia | Carbamazepine | 5.13 | 19549232 | |
| MESH:D004938 | Esophageal Neoplasms | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | 1.90 | 20426865 | |
| MESH:D005076 | Exanthema | Carbamazepine | 4.87 | 20485159 | |
| MESH:D005124 | Eye Abnormalities | Tetrachlorodibenzodioxin | 7.33 | 11564622 | |
| MESH:D005124 | Eye Abnormalities | Tretinoin | 7.33 | 16938888 9664655 | |
| MESH:D005234 | Fatty Liver | Amiodarone | 6.26 | 14986274 | |
| MESH:D005234 | Fatty Liver | Valproic Acid | 6.26 | 14986274 19224547 | |
| MESH:D005313 | Fetal Death | Tetrachlorodibenzodioxin | 2.88 | 11858732 | |
| MESH:D005315 | Fetal Diseases | Valproic Acid | 4.28 | 16575769 | |
| MESH:D005317 | Fetal Growth Retardation | Valproic Acid | 3.57 | 8888407 18558336 | |
| MESH:D018222 | Fibromatosis, Aggressive | Doxorubicin | 4.00 | 19069698 | |
| MESH:D005355 | Fibrosis | Quercetin | 11.50 | 19474275 | |
| MESH:D005355 | Fibrosis | Tetrachlorodibenzodioxin | 11.50 | 20067830 | |
| MESH:D005355 | Fibrosis | Tretinoin | 11.50 | 17994277 | |
| MESH:D005909 | Glioblastoma | Doxorubicin | 13.66 | 17150277 | |
| MESH:D005909 | Glioblastoma | Quercetin | 13.66 | 19804834 | |
| MESH:D005909 | Glioblastoma | Tretinoin | 13.66 | 17312396 | |
| MESH:D005909 | Glioblastoma | trichostatin A | 13.66 | 18801729 | |
| MESH:D005910 | Glioma | therapeutic | 12489024 | ||
| MESH:D005910 | Glioma | Quercetin | 6.09 | 17643826 | |
| MESH:D005910 | Glioma | Sodium Iodide | 6.09 | 12489024 | |
| MESH:D006042 | Goiter | perchlorate | 4.76 | 18801409 | |
| MESH:D006058 | Gonadal Disorders | Tetrachlorodibenzodioxin | 3.99 | 10696789 | |
| MESH:D006258 | Head and Neck Neoplasms | decitabine | 10.57 | 19215824 | |
| MESH:D006258 | Head and Neck Neoplasms | Doxorubicin | 10.57 | 15692506 | |
| MESH:D006258 | Head and Neck Neoplasms | Tretinoin | 10.57 | 16096774 | |
| MESH:D006317 | Hearing Loss, Noise-Induced | Tretinoin | 4.55 | 16084493 | |
| MESH:D006330 | Heart Defects, Congenital | 3,4,5,3',4'-pentachlorobiphenyl | 9.30 | 17686920 20471113 | |
| MESH:D006330 | Heart Defects, Congenital | Tetrachlorodibenzodioxin | 9.30 | 10048152 11294989 | |
| MESH:D006330 | Heart Defects, Congenital | Tretinoin | 9.30 | 9664655 14991402 | |
| MESH:D006331 | Heart Diseases | Doxorubicin | 3.06 | 16495754 18674790 18006777 16144979 17875725 12587719 16879835 17888722 16244372 16330681 16244371 14766674 16707910 | |
| MESH:D006333 | Heart Failure | Doxorubicin | 2.96 | 17481944 | |
| MESH:D006394 | Hemangiosarcoma | Doxorubicin | 3.37 | 15692506 | |
| MESH:D006470 | Hemorrhage | Tetrachlorodibenzodioxin | 2.80 | 11000095 | |
| MESH:D006529 | Hepatomegaly | Amiodarone | 6.64 | 15265979 | |
| MESH:D006529 | Hepatomegaly | Tetrachlorodibenzodioxin | 6.64 | 16120746 12621046 15340226 | |
| MESH:D006548 | Hernia, Diaphragmatic | Dexamethasone | 2.83 | 7520565 | |
| MESH:D006558 | Herpes Genitalis | Estradiol | 4.43 | 15709030 | |
| MESH:D006689 | Hodgkin Disease | Doxorubicin | 2.92 | 15147373 18501091 17606976 | |
| MESH:D019584 | Hot Flashes | Estradiol | 3.15 | 17088409 | |
| MESH:D006849 | Hydrocephalus | Valproic Acid | 4.27 | 17688650 | |
| MESH:D006869 | Hydronephrosis | Tetrachlorodibenzodioxin | 3.44 | 18606429 16354765 15340226 8697196 16959395 | |
| MESH:D006930 | Hyperalgesia | Tretinoin | 2.75 | 16870215 | |
| MESH:D006937 | Hypercholesterolemia | Amiodarone | 3.35 | 9751232 8137927 | |
| MESH:D017681 | Hypereosinophilic Syndrome | Tretinoin | 3.99 | 16778211 | |
| MESH:D006943 | Hyperglycemia | Quercetin | 3.52 | 18262572 11834736 | |
| MESH:D020138 | Hyperhomocysteinemia | Carbamazepine | 4.22 | 10459572 | |
| MESH:D006965 | Hyperplasia | Carbamazepine | 4.63 | 18773962 | |
| MESH:D006973 | Hypertension | Dexamethasone | 10.30 | 17042910 | |
| MESH:D006973 | Hypertension | Ouabain | 10.30 | 18976649 | |
| MESH:D006973 | Hypertension | Quercetin | 10.30 | 18356687 | |
| MESH:D006973 | Hypertension | Tetrachlorodibenzodioxin | 10.30 | 18850075 18670907 | |
| MESH:D006980 | Hyperthyroidism | Methimazole | 5.05 | 14678291 | |
| MESH:D007037 | Hypothyroidism | Amiodarone | 9.90 | 18020914 17991464 | |
| MESH:D007037 | Hypothyroidism | Methimazole | 9.90 | 18031379 | |
| MESH:D007077 | Ileal Diseases | 1-Methyl-3-isobutylxanthine | 4.84 | 18306037 | |
| MESH:D007248 | Infertility, Male | decitabine | 2.80 | 17581917 | |
| MESH:D007249 | Inflammation | Dexamethasone | 6.65 | 11099482 8960868 | |
| MESH:D007249 | Inflammation | Iodine | 6.65 | 16001271 | |
| MESH:D007249 | Inflammation | Tetrachlorodibenzodioxin | 6.65 | 12200463 12878042 | |
| MESH:D007251 | Influenza, Human | Nordihydroguaiaretic Acid | 9.63 | 18473937 | |
| MESH:D007251 | Influenza, Human | Quercetin | 9.63 | 16624496 | |
| MESH:D007333 | Insulin Resistance | Estradiol | 2.56 | 16393666 16627594 | |
| MESH:D007410 | Intestinal Diseases | Tretinoin | 3.19 | 17994277 | |
| MESH:D007569 | Jaw Abnormalities | Tetrachlorodibenzodioxin | 8.16 | 16580747 | |
| MESH:D007569 | Jaw Abnormalities | Tretinoin | 8.16 | 15992940 17551590 | |
| MESH:D007579 | Jejunal Diseases | 1-Methyl-3-isobutylxanthine | 4.84 | 18306037 | |
| MESH:D007627 | Keloid | Quercetin | 4.38 | 17086741 | |
| MESH:D017492 | Keratosis, Seborrheic | alitretinoin | 5.04 | 16144296 | |
| MESH:D007674 | Kidney Diseases | Doxorubicin | 8.06 | 15699352 16775033 15369732 | |
| MESH:D007674 | Kidney Diseases | Estradiol | 8.06 | 15618244 | |
| MESH:D007674 | Kidney Diseases | Quercetin | 8.06 | 16962696 | |
| MESH:D007676 | Kidney Failure, Chronic | Doxorubicin | 3.62 | 16707910 | |
| MESH:D007680 | Kidney Neoplasms | therapeutic | 12489024 | ||
| MESH:D007680 | Kidney Neoplasms | Estradiol | 6.70 | 15610895 | |
| MESH:D007680 | Kidney Neoplasms | Sodium Iodide | 6.70 | 12489024 | |
| MESH:D007938 | Leukemia | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | 16.24 | 12970779 | |
| MESH:D007938 | Leukemia | Azacitidine | 16.24 | 19148494 | |
| MESH:D007938 | Leukemia | decitabine | 16.24 | 19235587 18980019 | |
| MESH:D007938 | Leukemia | Quercetin | 16.24 | 17468513 | |
| MESH:D007938 | Leukemia | Tretinoin | 16.24 | 17143497 | |
| MESH:D004915 | Leukemia, Erythroblastic, Acute | Doxorubicin | 12.22 | 16085563 | |
| MESH:D004915 | Leukemia, Erythroblastic, Acute | troglitazone | 12.22 | 16085563 | |
| MESH:D007951 | Leukemia, Myeloid | Azacitidine | 13.04 | 19077051 | |
| MESH:D007951 | Leukemia, Myeloid | decitabine | 13.04 | 17236224 18454857 19117987 | |
| MESH:D007951 | Leukemia, Myeloid | Tretinoin | 13.04 | 19285840 16932348 16482212 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | Azacitidine | 10.12 | 17596541 18720364 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | decitabine | 10.12 | 19387464 18704418 18460780 17679729 19010910 18206229 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | Tretinoin | 10.12 | 16294345 19850784 17596541 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | trichostatin A | 10.12 | 18206229 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | Valproic Acid | 10.12 | 16294345 17596541 | |
| MESH:D015477 | Leukemia, Myelomonocytic, Chronic | decitabine | 4.86 | 18055864 | |
| MESH:D054429 | Leukemia, Myelomonocytic, Juvenile | Azacitidine | 4.64 | 19299654 | |
| MESH:D015473 | Leukemia, Promyelocytic, Acute | Tretinoin | 2.75 | 16140955 16788101 17368321 19075265 16766008 17107899 19225113 17339181 15748426 9834237 16935935 16891316 17217047 19642359 16331271 12679006 19035177 17506722 19029980 17294898 17301526 16823087 17361223 17712046 17649720 | |
| MESH:D017880 | Limb Deformities, Congenital | Tretinoin | 2.87 | 9224671 | |
| MESH:D008064 | Lipidoses | Amiodarone | 3.07 | 17567588 15342952 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Adenosine | 9.33 | 18263696 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Dexamethasone | 9.33 | 16718785 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Doxorubicin | 9.33 | 16595196 16439617 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Estradiol | 9.33 | 14716833 14659978 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Quercetin | 9.33 | 12741479 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Tetrachlorodibenzodioxin | 9.33 | 12878042 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Tretinoin | 9.33 | 18397230 16248980 | |
| MESH:D008113 | Liver Neoplasms | Ethylenethiourea | 6.15 | 11940454 | |
| MESH:D008113 | Liver Neoplasms | Quercetin | 6.15 | 18980244 | |
| MESH:D008113 | Liver Neoplasms | Tetrachlorodibenzodioxin | 6.15 | 16984957 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Doxorubicin | 7.64 | 16842330 17085340 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Quercetin | 7.64 | 19519916 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Tetrachlorodibenzodioxin | 7.64 | 12151625 | |
| MESH:D008133 | Long QT Syndrome | Amiodarone | 3.12 | 17391786 15350150 11989578 | |
| MESH:D008171 | Lung Diseases | Amiodarone | 2.96 | 12587719 | |
| MESH:D017563 | Lung Diseases, Interstitial | Amiodarone | 9.26 | 18516814 | |
| MESH:D017563 | Lung Diseases, Interstitial | Valproic Acid | 9.26 | 17228818 | |
| MESH:D008175 | Lung Neoplasms | alitretinoin | 7.26 | 16413115 | |
| MESH:D008175 | Lung Neoplasms | Azacitidine | 7.26 | 21224363 | |
| MESH:D008175 | Lung Neoplasms | Dexamethasone | 7.26 | 11195469 15824018 | |
| MESH:D008175 | Lung Neoplasms | Doxorubicin | 7.26 | 17418594 6189445 | |
| MESH:D008175 | Lung Neoplasms | Quercetin | 7.26 | 16280456 | |
| MESH:D008175 | Lung Neoplasms | Tetrachlorodibenzodioxin | 7.26 | 19555203 11884234 | |
| MESH:D008180 | Lupus Erythematosus, Systemic | Carbamazepine | 3.37 | 16628512 | |
| MESH:D008223 | Lymphoma | decitabine | 6.27 | 19470736 | |
| MESH:D008223 | Lymphoma | Doxorubicin | 6.27 | 16098063 | |
| MESH:D008228 | Lymphoma, Non-Hodgkin | Doxorubicin | 3.30 | 17654614 | |
| MESH:D016399 | Lymphoma, T-Cell | Doxorubicin | 3.99 | 15621674 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Doxorubicin | 7.95 | 15458769 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Estradiol | 7.95 | 11807958 11408345 17203775 16891317 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Iodine | 7.95 | 15922087 | |
| MESH:D020149 | Manganese Poisoning | Estradiol | 3.88 | 19453300 | |
| MESH:D008527 | Medulloblastoma | Tretinoin | 2.52 | 17453147 | |
| MESH:D008545 | Melanoma | therapeutic | 12489024 | ||
| MESH:D008545 | Melanoma | decitabine | 8.32 | 16505122 17785578 | |
| MESH:D008545 | Melanoma | Doxorubicin | 8.32 | 16827129 | |
| MESH:D008545 | Melanoma | Sodium Iodide | 8.32 | 12489024 | |
| MESH:D008545 | Melanoma | Tretinoin | 8.32 | 16752155 | |
| MESH:D008545 | Melanoma | trichostatin A | 8.32 | 16505122 | |
| MESH:D008591 | Meningomyelocele | Tretinoin | 3.85 | 16940565 | |
| MESH:D008607 | Mental Retardation | Carbamazepine | 3.49 | 9014606 | |
| MESH:D008654 | Mesothelioma | Doxorubicin | 2.79 | 17638057 | |
| MESH:D008881 | Migraine Disorders | Valproic Acid | 2.76 | 18765137 18803445 | |
| MESH:D028361 | Mitochondrial Diseases | Doxorubicin | 3.96 | 15792986 | |
| MESH:D009006 | Monosomy | Azacitidine | 5.48 | 19299654 | |
| MESH:D052016 | Mucositis | Doxorubicin | 4.20 | 17415656 | |
| MESH:D009101 | Multiple Myeloma | Azacitidine | 13.78 | 19549372 18443271 | |
| MESH:D009101 | Multiple Myeloma | decitabine | 13.78 | 18172295 | |
| MESH:D009101 | Multiple Myeloma | Dexamethasone | 13.78 | 16118317 15867202 15744524 | |
| MESH:D009101 | Multiple Myeloma | trichostatin A | 13.78 | 18172295 | |
| MESH:D009139 | Musculoskeletal Abnormalities | Valproic Acid | 3.49 | 8888407 | |
| MESH:D009181 | Mycoses | Amiodarone | 4.30 | 12754197 17974566 | |
| MESH:D009190 | Myelodysplastic Syndromes | Azacitidine | 19.20 | 17596541 19805378 17611569 18720364 | |
| MESH:D009190 | Myelodysplastic Syndromes | decitabine | 19.20 | 19157545 18608210 16882708 19010910 | |
| MESH:D009190 | Myelodysplastic Syndromes | Dexamethasone | 19.20 | 9809623 | |
| MESH:D009190 | Myelodysplastic Syndromes | Tretinoin | 19.20 | 17596541 | |
| MESH:D009190 | Myelodysplastic Syndromes | Valproic Acid | 19.20 | 17596541 | |
| MESH:D009203 | Myocardial Infarction | Doxorubicin | 5.08 | 15857846 19429709 | |
| MESH:D009203 | Myocardial Infarction | Quercetin | 5.08 | 19595682 | |
| MESH:D017202 | Myocardial Ischemia | Tetrachlorodibenzodioxin | 2.54 | 12213967 | |
| MESH:D015428 | Myocardial Reperfusion Injury | Estradiol | 7.02 | 16810080 | |
| MESH:D015428 | Myocardial Reperfusion Injury | Quercetin | 7.02 | 19207477 | |
| MESH:D009224 | Myotonia Congenita | Carbamazepine | 4.87 | 20399394 | |
| MESH:D009362 | Neoplasm Metastasis | Doxorubicin | 2.69 | 18259882 | |
| MESH:D009369 | Neoplasms | therapeutic | 15522214 | ||
| MESH:D009369 | Neoplasms | alitretinoin | 9.25 | 16946489 | |
| MESH:D009369 | Neoplasms | decitabine | 9.25 | 19116145 17925555 19470736 | |
| MESH:D009369 | Neoplasms | Quercetin | 9.25 | 15185748 | |
| MESH:D009369 | Neoplasms | Tretinoin | 9.25 | 16946489 16594593 | |
| MESH:D009389 | Neovascularization, Pathologic | Estradiol | 3.14 | 17289903 | |
| MESH:D009401 | Nephrosis | Doxorubicin | 4.19 | 16636307 16899518 | |
| MESH:D009404 | Nephrotic Syndrome | Doxorubicin | 3.50 | 16889571 15640375 | |
| MESH:D009421 | Nervous System Malformations | Carbamazepine | 18.88 | 16990009 | |
| MESH:D009421 | Nervous System Malformations | Estradiol | 18.88 | 11399458 16427766 | |
| MESH:D009421 | Nervous System Malformations | Tetrachlorodibenzodioxin | 18.88 | 14600291 | |
| MESH:D009421 | Nervous System Malformations | Tretinoin | 18.88 | 9125849 | |
| MESH:D009436 | Neural Tube Defects | Tretinoin | 5.95 | 9142499 | |
| MESH:D009436 | Neural Tube Defects | Valproic Acid | 5.95 | 16359493 8888407 | |
| MESH:D009447 | Neuroblastoma | Doxorubicin | 2.93 | 15555623 | |
| MESH:D020078 | Neurogenic Inflammation | Quercetin | 3.81 | 17929310 | |
| MESH:D010018 | Osteomalacia | Carbamazepine | 4.87 | 17016548 | |
| MESH:D015663 | Osteoporosis, Postmenopausal | Quercetin | 3.67 | 19495926 | |
| MESH:D012516 | Osteosarcoma | Doxorubicin | 3.63 | 15930896 | |
| MESH:D010051 | Ovarian Neoplasms | therapeutic | 12489024 | ||
| MESH:D010051 | Ovarian Neoplasms | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | 19.42 | 16211241 | |
| MESH:D010051 | Ovarian Neoplasms | decitabine | 19.42 | 19331143 19259094 | |
| MESH:D010051 | Ovarian Neoplasms | Estradiol | 19.42 | 19401270 | |
| MESH:D010051 | Ovarian Neoplasms | Quercetin | 19.42 | 19005980 | |
| MESH:D010051 | Ovarian Neoplasms | Sodium Iodide | 19.42 | 12489024 | |
| MESH:D010051 | Ovarian Neoplasms | Tretinoin | 19.42 | 16936753 | |
| MESH:D010051 | Ovarian Neoplasms | trichostatin A | 19.42 | 19331143 | |
| MESH:D010146 | Pain | Carbamazepine | 5.61 | 15215642 | |
| MESH:D010146 | Pain | Tretinoin | 5.61 | 16870215 | |
| MESH:D010190 | Pancreatic Neoplasms | decitabine | 10.30 | 19294695 | |
| MESH:D010190 | Pancreatic Neoplasms | Quercetin | 10.30 | 16965848 | |
| MESH:D010190 | Pancreatic Neoplasms | Tretinoin | 10.30 | 15976015 | |
| MESH:D010190 | Pancreatic Neoplasms | trichostatin A | 10.30 | 19294695 | |
| MESH:D010267 | Parapsoriasis | Carbamazepine | 5.12 | 16538176 | |
| OMIM:167400 | PAROXYSMAL EXTREME PAIN DISORDER | Carbamazepine | 5.33 | 17145499 17679678 | |
| MESH:D010382 | Peliosis Hepatis | Tetrachlorodibenzodioxin | 3.64 | 12520081 | |
| MESH:D003557 | Phyllodes Tumor | Doxorubicin | 4.55 | 17983394 | |
| MESH:D010997 | Pleural Neoplasms | Doxorubicin | 4.55 | 17638057 | |
| MESH:D017499 | Porokeratosis | alitretinoin | 5.40 | 16144296 | |
| MESH:D017119 | Porphyria Cutanea Tarda | Tetrachlorodibenzodioxin | 3.00 | 18163543 | |
| MESH:D011230 | Precancerous Conditions | Quercetin | 3.48 | 19056647 | |
| MESH:D054198 | Precursor Cell Lymphoblastic Leukemia-Lymphoma | Dexamethasone | 3.19 | 21297632 | |
| MESH:D011248 | Pregnancy Complications | Carbamazepine | 4.58 | 9014606 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | Carbamazepine | 12.96 | 9014606 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | Tetrachlorodibenzodioxin | 12.96 | 11118676 11896295 11399792 11222880 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | Valproic Acid | 12.96 | 20603192 | |
| MESH:D055728 | Primary Myelofibrosis | decitabine | 10.50 | 17616702 | |
| MESH:D055728 | Primary Myelofibrosis | trichostatin A | 10.50 | 17616702 | |
| MESH:D019048 | Prostatic Intraepithelial Neoplasia | Estradiol | 3.35 | 20887781 | |
| MESH:D011471 | Prostatic Neoplasms | therapeutic | 12489024 14633711 | ||
| MESH:D011471 | Prostatic Neoplasms | Azacitidine | 2.00 | 18324645 | |
| MESH:D011471 | Prostatic Neoplasms | Doxorubicin | 2.00 | 16888761 16729912 15749863 18437689 15897917 16868541 | |
| MESH:D011471 | Prostatic Neoplasms | Estradiol | 2.00 | 16740699 | |
| MESH:D011471 | Prostatic Neoplasms | Nordihydroguaiaretic Acid | 2.00 | 18491370 | |
| MESH:D011471 | Prostatic Neoplasms | Quercetin | 2.00 | 14715546 17292933 | |
| MESH:D011471 | Prostatic Neoplasms | Sodium Iodide | 2.00 | 12489024 | |
| MESH:D011471 | Prostatic Neoplasms | trichostatin A | 2.00 | 18798265 19789329 | |
| MESH:D011507 | Proteinuria | Tretinoin | 3.06 | 16636307 | |
| MESH:D019310 | Pseudolymphoma | Carbamazepine | 10.59 | 9591791 12752131 | |
| MESH:D019310 | Pseudolymphoma | Valproic Acid | 10.59 | 12752131 11422049 | |
| MESH:D011565 | Psoriasis | tazarotene | 4.78 | 15989518 16605289 | |
| MESH:D011625 | Pterygium | Tretinoin | 4.20 | 16723453 | |
| MESH:D011658 | Pulmonary Fibrosis | Amiodarone | 5.31 | 11597910 12832656 12490602 | |
| MESH:D011658 | Pulmonary Fibrosis | troglitazone | 5.31 | 18162602 | |
| MESH:D051437 | Renal Insufficiency | Doxorubicin | 3.65 | 17922066 | |
| MESH:D012128 | Respiratory Distress Syndrome, Adult | Dexamethasone | 3.47 | 11700416 18379247 | |
| MESH:D015619 | Respiratory System Abnormalities | Tetrachlorodibenzodioxin | 3.27 | 18990726 | |
| MESH:D012208 | Rhabdomyosarcoma | decitabine | 15.35 | 19155313 | |
| MESH:D012208 | Rhabdomyosarcoma | Tretinoin | 15.35 | 16116481 16283617 | |
| MESH:D012208 | Rhabdomyosarcoma | Valproic Acid | 15.35 | 19155313 | |
| MESH:D012509 | Sarcoma | Doxorubicin | 3.47 | 17710206 16767912 18313854 15675481 15625365 17203757 | |
| MESH:D012512 | Sarcoma, Ewing's | Doxorubicin | 3.68 | 16326096 14601052 | |
| MESH:D012514 | Sarcoma, Kaposi | Doxorubicin | 4.20 | 17846226 | |
| MESH:D012554 | Schistosomiasis japonica | Quercetin | 4.94 | 16862918 | |
| MESH:D012559 | Schizophrenia | Valproic Acid | 1.98 | 15737665 19110320 | |
| MESH:D012640 | Seizures | Carbamazepine | 5.03 | 16876388 16180713 19414003 16938433 9046859 9844417 15946322 | |
| MESH:D012640 | Seizures | Valproic Acid | 5.03 | 16876388 11044598 14763951 17978042 11738929 1511512 15475178 3137016 | |
| OMIM:609620 | SHORT QT SYNDROME 1 | Amiodarone | 4.49 | 18724381 | |
| MESH:D012878 | Skin Neoplasms | Doxorubicin | 7.63 | 15692506 | |
| MESH:D012878 | Skin Neoplasms | Tetrachlorodibenzodioxin | 7.63 | 16192470 | |
| MESH:D012878 | Skin Neoplasms | Tretinoin | 7.63 | 16467112 | |
| MESH:D012893 | Sleep Disorders | Carbamazepine | 4.53 | 19414003 | |
| MESH:D012983 | Soft Tissue Neoplasms | Doxorubicin | 3.99 | 16767912 17203757 15625365 | |
| MESH:D016135 | Spinal Dysraphism | Valproic Acid | 3.31 | 19490988 | |
| MESH:D013226 | Status Epilepticus | Valproic Acid | 3.94 | 12833885 | |
| MESH:D013262 | Stevens-Johnson Syndrome | Carbamazepine | 4.63 | 19694795 15057820 16415921 16538176 19915237 18855540 20485159 | |
| MESH:D013272 | Stomach Diseases | Dexamethasone | 3.73 | 15472012 | |
| MESH:D013274 | Stomach Neoplasms | decitabine | 3.16 | 19037991 | |
| MESH:D013274 | Stomach Neoplasms | Tretinoin | 3.16 | 17261132 | |
| MESH:D013274 | Stomach Neoplasms | troglitazone | 3.16 | 15930296 | |
| MESH:D013276 | Stomach Ulcer | Amiodarone | 5.74 | 18087811 | |
| MESH:D013276 | Stomach Ulcer | Dexamethasone | 5.74 | 15138204 | |
| MESH:D013610 | Tachycardia | Amiodarone | 3.73 | 11238279 | |
| MESH:D017180 | Tachycardia, Ventricular | Amiodarone | 3.63 | 19225199 | |
| MESH:D013959 | Thyroid Diseases | Amiodarone | 17.64 | 19731979 | |
| MESH:D013959 | Thyroid Diseases | Tetrachlorodibenzodioxin | 17.64 | 12697716 | |
| MESH:D013959 | Thyroid Diseases | Thyroxine | 17.64 | 19910387 | |
| OMIM:274400 | THYROID DYSHORMONOGENESIS 1 | marker/mechanism | |||
| MESH:D013964 | Thyroid Neoplasms | marker/mechanism|therapeutic | 17045167 16954431 | ||
| MESH:D013964 | Thyroid Neoplasms | Butyrates | 22.13 | 17967635 | |
| MESH:D013964 | Thyroid Neoplasms | decitabine | 22.13 | 17967635 | |
| MESH:D013964 | Thyroid Neoplasms | Doxorubicin | 22.13 | 17909728 16010429 | |
| MESH:D013964 | Thyroid Neoplasms | Ethylenethiourea | 22.13 | 11940454 | |
| MESH:D013964 | Thyroid Neoplasms | potassium perchlorate | 22.13 | 15053237 | |
| MESH:D013964 | Thyroid Neoplasms | Tretinoin | 22.13 | 16026305 17045167 | |
| MESH:D013971 | Thyrotoxicosis | Amiodarone | 4.28 | 19584973 18020914 | |
| MESH:D013978 | Tibial Fractures | Estradiol | 4.08 | 19048282 | |
| MESH:D014062 | Tongue Neoplasms | Tretinoin | 3.27 | 16051514 | |
| MESH:D016171 | Torsades de Pointes | Amiodarone | 3.60 | 17467628 11989578 | |
| MESH:D014178 | Translocation, Genetic | Valproic Acid | 4.63 | 17262798 | |
| MESH:D014376 | Tuberculosis | Tretinoin | 2.84 | 16040207 | |
| MESH:D020194 | Unverricht-Lundborg Syndrome | Valproic Acid | 3.93 | 3119515 | |
| MESH:D001749 | Urinary Bladder Neoplasms | decitabine | 6.89 | 17616700 19087683 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Doxorubicin | 6.89 | 17653716 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Quercetin | 6.89 | 16720314 | |
| MESH:D014564 | Urogenital Abnormalities | Valproic Acid | 4.06 | 8888407 | |
| MESH:D002583 | Uterine Cervical Neoplasms | Tretinoin | 3.16 | 16129372 | |
| MESH:D014604 | Uveal Neoplasms | decitabine | 10.82 | 17785578 | |
| MESH:D014604 | Uveal Neoplasms | Tretinoin | 10.82 | 16752155 | |
| MESH:D014605 | Uveitis | Dexamethasone | 4.21 | 1336536 | |
| MESH:D054079 | Vascular Malformations | Tetrachlorodibenzodioxin | 3.99 | 12125929 | |
| MESH:D018487 | Ventricular Dysfunction, Left | Doxorubicin | 3.65 | 17638931 17334414 17678736 16364871 | |
| MESH:D014820 | Vitiligo | Tretinoin | 3.49 | 16761959 | |
| MESH:D019282 | Wasting Syndrome | Tetrachlorodibenzodioxin | 3.64 | 15886252 | |
| MESH:D009396 | Wilms Tumor | Tretinoin | 3.46 | 16287080 |
| Pathway ID | Pathway Name |
|---|---|
| REACT:19419 | Amino acid and oligopeptide SLC transporters |
| REACT:15314 | Hormone biosynthesis |
| REACT:13 | Metabolism of amino acids and derivatives |
| REACT:15518 | Transmembrane transport of small molecules |
Drug Bank