AutismKB 2.0

Annotation Detail for SLC6A12


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Basic Information Top
Gene Symbol:SLC6A12 ( BGT-1,BGT1,FLJ38727 )
Gene Full Name: solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
Band: 12p13.33
Quick LinksEntrez ID:6539; OMIM: 603080; Uniprot ID:S6A12_HUMAN; ENSEMBL ID: ENSG00000111181; HGNC ID: 11045
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Amine compound SLC transporters
Synaptic Transmission
Transmembrane transport of small molecules
Amino acid and oligopeptide SLC transporters
Metabolism of amino acids and derivatives
No data
No data
Pathway IDPathway Name
500341Amino acid transport across the plasma membrane
500357Na+/Cl- dependent neurotransmitter transporters
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of SLC6A12 mRNAdecreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of SLC6A12 mRNAaffects expression 17562736
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of SLC6A12 proteinaffects expression 20106945
D005680 gamma-Aminobutyric Acid SLC6A12 protein affects the transport of gamma-Aminobutyric Acidaffects transport 15368537
D005680 gamma-Aminobutyric Acid SLC6A12 protein affects the uptake of gamma-Aminobutyric Acidaffects uptake 12634427
D000625 Aminooxyacetic Acid Aminooxyacetic Acid results in decreased activity of SLC6A12 proteindecreases activity 12634427
D000643 Ammonium Chloride Ammonium Chloride affects the expression of SLC6A12 mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in decreased expression of SLC6A12 mRNAdecreases expression 19128835
D001761 Bleomycin Bleomycin results in increased expression of SLC6A12 mRNAincreases expression 15808516
D002713 Chlorine [Ozone co-treated with Chlorine] results in increased expression of SLC6A12 mRNAaffects cotreatment|increases expression 18636392
D016572 Cyclosporine Cyclosporine results in decreased expression of SLC6A12 mRNAdecreases expression 20106945
D003975 Diazepam Diazepam results in increased expression of SLC6A12 mRNAincreases expression 15802192
D002945 Cisplatin SLC6A12 protein affects the susceptibility to Cisplatinaffects response to substance 16217747
D004958 Estradiol Estradiol results in decreased expression of SLC6A12 mRNAdecreases expression 20106945
D005419 Flavonoids Flavonoids results in decreased expression of SLC6A12 mRNAdecreases expression 18035473
C056933 fumonisin B1 fumonisin B1 results in decreased expression of SLC6A12 mRNAdecreases expression 16221962
C029424 hydrazine hydrazine results in decreased activity of SLC6A12 proteindecreases activity 12634427
C030517 myxothiazol myxothiazol inhibits the reaction [Sodium Chloride results in increased expression of SLC6A12 mRNA]decreases reaction|increases expression 16303854
D010126 Ozone [Ozone co-treated with Chlorine] results in increased expression of SLC6A12 mRNAaffects cotreatment|increases expression 18636392
C076994 perfluorooctane sulfonic acid perfluorooctane sulfonic acid results in decreased expression of SLC6A12 mRNAdecreases expression 16221955
C033457 phenobarbital quinidine phenobarbital quinidine results in increased expression of SLC6A12 mRNAincreases expression 15802192
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of SLC6A12 mRNAaffects binding|decreases expression|increases activity 19710929
C006253 pirinixic acid pirinixic acid results in decreased expression of SLC6A12 mRNAdecreases expression 16221962
D012402 Rotenone Rotenone inhibits the reaction [Sodium Chloride results in increased expression of SLC6A12 mRNA]decreases reaction|increases expression 16303854
D012965 Sodium Chloride myxothiazol inhibits the reaction [Sodium Chloride results in increased expression of SLC6A12 mRNA]decreases reaction|increases expression 16303854
D012965 Sodium Chloride Rotenone inhibits the reaction [Sodium Chloride results in increased expression of SLC6A12 mRNA]decreases reaction|increases expression 16303854
D012965 Sodium Chloride Sodium Chloride results in increased expression of SLC6A12 mRNAincreases expression 16303854
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 3.4118287403
MESH:D058186 Acute Kidney Injury Cisplatin 3.8215814532 12690470 17670903
MESH:D055371 Acute Lung Injury Bleomycin 14.6117118201
MESH:D055371 Acute Lung Injury Chlorine 14.6120601635
MESH:D055371 Acute Lung Injury pirinixic acid 14.6118653653
MESH:D000230 Adenocarcinoma arsenic trioxide 6.9411798837 19825857
MESH:D000230 Adenocarcinoma Cisplatin 6.9417638652 11798837
MESH:D000230 Adenocarcinoma Estradiol 6.9411473722
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.673712494
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.3316434500
MESH:D000544 Alzheimer Disease Ozone 2.4115513908
MESH:D000799 Angioedema Acetaminophen 3.6910982225
MESH:D000860 Anoxia Bleomycin 5.2615782499
MESH:D001008 Anxiety Disorders Diazepam 5.0716284244 18313124
MESH:D001172 Arthritis, Rheumatoid Ozone 2.5215570426
MESH:D001249 Asthma Ozone 2.5916373670 17854713
MESH:D001321 Autistic Disorder Acetaminophen 1.4318445737
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.871440618 11289319
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 8.5416206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.5419483382
MESH:D019046 Bone Marrow Neoplasms Cisplatin 4.7314601052
MESH:D001943 Breast Neoplasms Cisplatin 2.3719526202 18382427
MESH:D001943 Breast Neoplasms Estradiol 2.3712948864 17018787 19861407 17289903 17261762 16675129 14630087 18497071
MESH:D016535 Bronchial Hyperreactivity Ozone 3.5615516495 14754758 16777450 17626835 18417511 19059883 18315731
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.1911589617
MESH:D002100 Cachexia Ozone 4.5916183385
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.3116111702
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 11.073581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 11.073084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 11.0712907637 12619106 21507988
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 11.0714691202 16217749 15073043 11135700 15553829
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 11.0717982673
MESH:D006528 Carcinoma, Hepatocellular Estradiol 11.0716924424
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 2.9816685392 12023789
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.7219014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.617296757
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.9812490120
MESH:D002294 Carcinoma, Squamous Cell Bleomycin 5.186189445
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 5.186189445 17066447 18337622
MESH:D002386 Cataract Acetaminophen 2.4910977129
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 10.547505956
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 10.5412371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 10.5418566989
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 12.7319486331 9022650
MESH:D002779 Cholestasis Cyclosporine 12.7319486331
MESH:D002779 Cholestasis pirinixic acid 12.7319176532
MESH:D002972 Cleft Palate Diazepam 4.303629520
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.6320501625
MESH:D015179 Colorectal Neoplasms Cisplatin 2.6315273666
MESH:D023903 Coronary Restenosis arsenic trioxide 4.0412609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 1.8710525206
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.9515213294
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.6611298694 11906362 8970840 14531868 8156756 2524372 18759878 12868966
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3618249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.353621924 2952479
MESH:D003928 Diabetic Nephropathies Estradiol 3.2819279558
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 6.0411289319 7440962 18692083 6679447 9022650 9653073 6482804 9328219 18289764 16192314 8291058 1440618 18648102
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.0416393943 12153990 15619225 18071297 16177239 11461765 19923254 15968718 16227642 14725611 11743745 16781746 16485898 17522070 19420014 17906064 12392966 10663392 12594235 14550746 11739529 11421492 19370779 12705907 2444490 10915739 10774834 19739265 18713872 11287661 17562736 12958197 19085960 12540782 14986274 11529661 19164858 19416960 16081117 16109766 11834606
MESH:D056486 Drug-Induced Liver Injury fumonisin B1 6.0416221962
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.9519426721
MESH:D004362 Drug Toxicity Cisplatin 3.7415033597 12649298 12231392 19839026
MESH:D004417 Dyspnea Chlorine 4.4720016425
MESH:D004421 Dystonia Diazepam 5.531851702
MESH:D004487 Edema Bleomycin 6.7717118201
MESH:D004487 Edema pirinixic acid 6.7712083418
MESH:D016889 Endometrial Neoplasms Estradiol 2.8818566989 11473722 19148513
MESH:D004828 Epilepsies, Partial Diazepam 5.393922381
MESH:D004827 Epilepsy Diazepam 4.48821787
MESH:D004832 Epilepsy, Absence Diazepam 5.086426943 6401628
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 7.093581430
MESH:D004938 Esophageal Neoplasms arsenic trioxide 7.0912903497
MESH:D004938 Esophageal Neoplasms Cisplatin 7.0916481741 15173087 17638652 15464296 16785472
MESH:D005234 Fatty Liver arsenic trioxide 12.2615073043
MESH:D005234 Fatty Liver Cyclosporine 12.2619224547
MESH:D005234 Fatty Liver pirinixic acid 12.2619236843 20131406
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.876705139
MESH:D005355 Fibrosis Cyclosporine 2.9912639820 12168785
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.1116904648
MESH:D005739 Gas Poisoning Chlorine 4.8620016425
MESH:D005756 Gastritis Acetaminophen 3.5216983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.078708960
MESH:D005909 Glioblastoma perfluorooctane sulfonic acid 4.1617162496
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.897505956
MESH:D006258 Head and Neck Neoplasms Cisplatin 3.6115102660 15464296
MESH:D034381 Hearing Loss Cisplatin 4.1719898482
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 4.2915464296
MESH:D006333 Heart Failure pirinixic acid 2.4420558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.2715720958
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.376705139
MESH:D006529 Hepatomegaly fumonisin B1 8.2716221962
MESH:D006529 Hepatomegaly pirinixic acid 8.2716221962 18467677 19176532 19772884
MESH:D006558 Herpes Genitalis Estradiol 4.8815709030
MESH:D006689 Hodgkin Disease Bleomycin 7.5717606976 15147373 18501091
MESH:D006689 Hodgkin Disease Cisplatin 7.5716200630 16170182
MESH:D019584 Hot Flashes Estradiol 3.6017088409
MESH:D006930 Hyperalgesia Acetaminophen 2.5816870215
MESH:D006943 Hyperglycemia pirinixic acid 3.0520558911
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.7915034207
MESH:D006973 Hypertension Cyclosporine 5.5410903974
MESH:D006973 Hypertension Sodium Chloride 5.5411507004
MESH:D007249 Inflammation Bleomycin 5.4317118201
MESH:D007249 Inflammation Flavonoids 5.4317296493
MESH:D007333 Insulin Resistance Estradiol 6.8716627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 6.8716306350
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.879022650 8074119
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.2915604871
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.9915464296
MESH:D007674 Kidney Diseases Acetaminophen 13.7212587719 15629191
MESH:D007674 Kidney Diseases Cisplatin 13.7218289764 12649298 19839026 15190930 12231392
MESH:D007674 Kidney Diseases Cyclosporine 13.7218776723 8314463 10903974
MESH:D007674 Kidney Diseases Estradiol 13.7215618244
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 11.646582329
MESH:D007680 Kidney Neoplasms Cyclosporine 11.6412371664
MESH:D007680 Kidney Neoplasms Estradiol 11.6415610895
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 4.6411231351
MESH:D016773 Leishmaniasis, Cutaneous Sodium Chloride 4.809499605
MESH:D007938 Leukemia arsenic trioxide 2.7615070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.6617077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.1516972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.3214633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.6219077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1116467208 16968895 20471514 17050201 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.1216823087 9834237 17649720 16330433 11161223 16331271 19075265 17217047 12712474 15336539 15213294 12018890 11468182 15748426 17712046 19035177 17107899 12679006 16891316 19642359 17869043 15622746 19225113 16112521 16966277
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.2016882451
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.109327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 2.2514716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 2.2515474484
MESH:D008107 Liver Diseases Acetaminophen 1.5916611625 19460945 16610002 11587558 12969438 19784758 12587719 19014921
MESH:D017114 Liver Failure, Acute Acetaminophen 3.1016871587 17185352
MESH:D008113 Liver Neoplasms Aflatoxin B1 7.102125692 15890375 9163691 18177683
MESH:D008113 Liver Neoplasms arsenic trioxide 7.1014682389
MESH:D008113 Liver Neoplasms pirinixic acid 7.1020007298 16377806 15890375
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 9.34598648 3712494 1399818 6587162
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 9.348603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 9.3420377131
MESH:D008133 Long QT Syndrome arsenic trioxide 3.2315213294
MESH:D008171 Lung Diseases Ozone 3.278266340 19066396
MESH:D055370 Lung Injury Ozone 3.7020417186
MESH:D008175 Lung Neoplasms Aflatoxin B1 6.4314755239
MESH:D008175 Lung Neoplasms arsenic trioxide 6.4319825857 11798837
MESH:D008175 Lung Neoplasms Bleomycin 6.436189445
MESH:D008175 Lung Neoplasms Cisplatin 6.436189445 17225452 11798837
MESH:D008175 Lung Neoplasms Ozone 6.438597069 7614698
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.4717203775 11807958 11408345 16891317
MESH:D020149 Manganese Poisoning Estradiol 4.3319453300
MESH:D008545 Melanoma Bleomycin 3.9015577320
MESH:D008545 Melanoma Cisplatin 3.9016432458 18332650 16248763 12374674 12393984 17761969 18505091 11135225 18176117 12883367 15577323 17023156 16809738
MESH:D018328 Melanoma, Amelanotic Cisplatin 4.6215990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.4219513568
MESH:D008654 Mesothelioma Cisplatin 3.1917638057
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.6416801185
MESH:D008679 Metaplasia Ozone 4.9610496685
MESH:D009101 Multiple Myeloma arsenic trioxide 3.0014977855 19549372 19417148 11468182 15949261
MESH:D009135 Muscular Diseases pirinixic acid 3.3616239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.5218349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.0616882451 16105982
MESH:D009203 Myocardial Infarction pirinixic acid 2.0819151258
MESH:D015428 Myocardial Reperfusion Injury Estradiol 7.8616810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.8616411023
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.8116624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.413581430
MESH:D009369 Neoplasms Cisplatin 4.8616773208
MESH:D009369 Neoplasms pirinixic acid 4.8617405874
MESH:D009389 Neovascularization, Pathologic Estradiol 3.5817289903
MESH:D009395 Nephritis, Interstitial Cisplatin 4.3415464296
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.2917954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.1519348381 18481113
MESH:D009410 Nerve Degeneration Rotenone 3.7617356569 18619942 15790535
MESH:D009421 Nervous System Malformations Estradiol 3.5016427766 11399458
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 6.926679447
MESH:D009436 Neural Tube Defects arsenic trioxide 6.9210525206
MESH:D009447 Neuroblastoma Cisplatin 3.378761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.7518514411
MESH:D017599 Neuroectodermal Tumors Cisplatin 4.558761367
MESH:D009765 Obesity pirinixic acid 1.7820558911
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.294026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.873988306
MESH:D010051 Ovarian Neoplasms arsenic trioxide 7.6616624393 19769630 12452020
MESH:D010051 Ovarian Neoplasms Cisplatin 7.6617225452 6897625 15464296 19769630
MESH:D010051 Ovarian Neoplasms Estradiol 7.6619401270
MESH:D010146 Pain Acetaminophen 2.2716870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 5.3015580305
MESH:D010190 Pancreatic Neoplasms Cisplatin 5.3019003803
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.337296757
MESH:D010235 Paraganglioma arsenic trioxide 4.0219927285
MESH:D010300 Parkinson Disease Rotenone 2.9211535288 19232380 16412576 18619942 19114014 15451049 11445065 18191903 16140633
MESH:D020734 Parkinsonian Disorders Rotenone 3.9418197244 15574749 15795934 15927086
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 4.1615464296
MESH:D010538 Peritonitis Ozone 3.9816369182
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.326228378
MESH:D010997 Pleural Neoplasms Cisplatin 5.1917638057
MESH:D011014 Pneumonia Bleomycin 10.9116317386 17071938 18024389
MESH:D011014 Pneumonia Ozone 10.9118007984 18381685 18929643
MESH:D011230 Precancerous Conditions Cyclosporine 3.0912371664
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.7520887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.2719131511
MESH:D011471 Prostatic Neoplasms Estradiol 3.2716740699
MESH:D011565 Psoriasis Cyclosporine 2.1816882103
MESH:D011654 Pulmonary Edema Bleomycin 5.1715808516
MESH:D011658 Pulmonary Fibrosis Bleomycin 3.8115541506 17434272 21435439 17241526 16314464 11554783 18162602 12574379 16115399 14609568 15322207 18008008 17177178 12624602
MESH:D051437 Renal Insufficiency Cisplatin 4.2615464296
MESH:D015427 Reperfusion Injury pirinixic acid 2.3119058328
MESH:D012120 Respiration Disorders Chlorine 5.0618579056
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.263692021
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 9.8616646077
MESH:D012512 Sarcoma, Ewing's Cisplatin 9.8614601052
MESH:D012640 Seizures Aminooxyacetic Acid 7.311511512
MESH:D012640 Seizures Diazepam 7.319754883 10087439 15946322
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 5.1915464296
MESH:D013274 Stomach Neoplasms arsenic trioxide 3.5817007042
MESH:D013274 Stomach Neoplasms Cisplatin 3.5817522103 15958060 18396642
MESH:D013274 Stomach Neoplasms Sodium Chloride 3.5816646055
MESH:D013375 Substance Withdrawal Syndrome Diazepam 5.319754883
MESH:D013736 Testicular Neoplasms Cisplatin 4.4915464296 17225452
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 6.776587162 6582329 7505956 3712494 1399818
MESH:D013964 Thyroid Neoplasms arsenic trioxide 6.7719014326
MESH:D013978 Tibial Fractures Estradiol 4.5319048282
MESH:D016171 Torsades de Pointes arsenic trioxide 3.8115213294
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 8.058074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 8.0511780464 12845720 12973940 20435036
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 8.0512973940 15464296 17225452
MESH:D014581 Urticaria Acetaminophen 2.8310982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 4.0716803524
MESH:D014605 Uveitis Cyclosporine 3.831336536
MESH:D014625 Vaginal Neoplasms Cisplatin 4.4615577323
MESH:D014839 Vomiting Cisplatin 4.5711897121
MESH:D015431 Weight Loss Bleomycin 5.4912624602
MESH:D014985 Xerophthalmia Cyclosporine 4.2917120751
Pathway ID Pathway Name
REACT:20679 Amine compound SLC transporters
REACT:19419 Amino acid and oligopeptide SLC transporters
REACT:13 Metabolism of amino acids and derivatives
REACT:13685 Synaptic Transmission
REACT:15518 Transmembrane transport of small molecules
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA35908
    • Releated gene ID Related gene Name
    PA35908SLC6A12
    No data
    Releated drug ID Related drug Name
    PA448055l-alanine
    PA448478l-arginine
    PA450197l-leucine
    PA450280l-lysine
    PA451330l-serine
    PA451822l-tyrosine
    PA451843l-valine
    PA451590taurine
    PA10323l-tryptophan
    PA449789glycine
    PA449173l-cysteine
    PA451125l-proline
    PA448603betaine
    PA451209quinidine
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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