AutismKB 2.0

Annotation Detail for OCM


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Basic Information Top
Gene Symbol:OCM ( MGC142264,MGC142266,MGC97453,MGC97465,MGC97477,OCM1,OM,ONCM )
Gene Full Name: oncomodulin
Band: 7p22.1
Quick LinksEntrez ID:654231; OMIM: 164795; Uniprot ID:ONCO_HUMAN; ENSEMBL ID: ENSG00000122543; HGNC ID: 8105
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000638 Amiodarone Amiodarone results in increased expression of OCM mRNAincreases expression 19774075
D000643 Ammonium Chloride Ammonium Chloride affects the expression of OCM mRNAaffects expression 16483693
C014347 decitabine [decitabine affects the methylation of OCM protein] which affects the expression of OCM mRNAaffects expression|affects methylation 18381416
D005419 Flavonoids Flavonoids results in decreased expression of OCM mRNAdecreases expression 18035473
D015058 1-Naphthylisothiocyanate 1-Naphthylisothiocyanate results in increased expression of OCM mRNAincreases expression 12832660
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.1018287403
MESH:D001145 Arrhythmias, Cardiac Amiodarone 4.1520041841 18218290 18057881
MESH:D001281 Atrial Fibrillation Amiodarone 4.1618651412 19698954
MESH:D001778 Blood Coagulation Disorders Amiodarone 4.2719483382
MESH:D001943 Breast Neoplasms decitabine 2.5419208741 18320071
MESH:D002294 Carcinoma, Squamous Cell decitabine 2.6719215824
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.9919225199 15710769
MESH:D002341 Carotid Artery Thrombosis Amiodarone 5.6218974383
MESH:D002761 Cholangitis 1-Naphthylisothiocyanate 6.8112912871
MESH:D002779 Cholestasis 1-Naphthylisothiocyanate 4.5916629650 15913567 18164287 12927374 18590720 15500046 7624871 19486331
MESH:D002780 Cholestasis, Intrahepatic 1-Naphthylisothiocyanate 6.4710220858 19407337
MESH:D003110 Colonic Neoplasms decitabine 2.3817616700
MESH:D015179 Colorectal Neoplasms decitabine 2.1018981723
MESH:D056486 Drug-Induced Liver Injury 1-Naphthylisothiocyanate 4.727624871 17522070 18289764 20133375
MESH:D056486 Drug-Induced Liver Injury Amiodarone 4.7215265979 18218290
MESH:D004701 Endocrine Gland Neoplasms decitabine 5.7319294695
MESH:D005234 Fatty Liver Amiodarone 3.8914986274
MESH:D006258 Head and Neck Neoplasms decitabine 3.7119215824
MESH:D006505 Hepatitis 1-Naphthylisothiocyanate 5.1318590720
MESH:D006529 Hepatomegaly Amiodarone 4.2315265979
MESH:D006937 Hypercholesterolemia Amiodarone 4.258137927 9751232
MESH:D007037 Hypothyroidism Amiodarone 5.0018020914 17991464
MESH:D007248 Infertility, Male decitabine 3.4217581917
MESH:D007249 Inflammation Flavonoids 2.8017296493
MESH:D007938 Leukemia decitabine 3.2219235587 18980019
MESH:D007951 Leukemia, Myeloid decitabine 4.3717236224 19117987 18454857
MESH:D015470 Leukemia, Myeloid, Acute decitabine 2.4219010910 19387464 18460780 18704418 17679729 18206229
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 6.0718055864
MESH:D008064 Lipidoses Amiodarone 3.7617567588 15342952
MESH:D008107 Liver Diseases 1-Naphthylisothiocyanate 3.2517184895
MESH:D008133 Long QT Syndrome Amiodarone 3.8515350150 11989578 17391786
MESH:D008171 Lung Diseases Amiodarone 3.6012587719
MESH:D017563 Lung Diseases, Interstitial Amiodarone 5.0918516814
MESH:D008223 Lymphoma decitabine 3.6619470736
MESH:D008545 Melanoma decitabine 2.2816505122 17785578
MESH:D009101 Multiple Myeloma decitabine 3.5918172295
MESH:D009181 Mycoses Amiodarone 5.5117974566 12754197
MESH:D009190 Myelodysplastic Syndromes decitabine 3.5616882708 18608210 19157545 19010910
MESH:D009369 Neoplasms decitabine 2.8619116145 19470736 17925555
MESH:D010051 Ovarian Neoplasms decitabine 2.7319259094 19331143
MESH:D010190 Pancreatic Neoplasms decitabine 2.8619294695
MESH:D010382 Peliosis Hepatis 1-Naphthylisothiocyanate 6.4720133375
MESH:D055728 Primary Myelofibrosis decitabine 5.2117616702
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.9611597910 12490602 12832656
MESH:D012208 Rhabdomyosarcoma decitabine 4.8119155313
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 5.6218724381
MESH:D013274 Stomach Neoplasms decitabine 2.1019037991
MESH:D013276 Stomach Ulcer Amiodarone 3.6818087811
MESH:D013610 Tachycardia Amiodarone 4.7311238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.6319225199
MESH:D013921 Thrombocytopenia 1-Naphthylisothiocyanate 5.1020133375
MESH:D013959 Thyroid Diseases Amiodarone 5.3719731979
MESH:D013964 Thyroid Neoplasms decitabine 3.6017967635
MESH:D013971 Thyrotoxicosis Amiodarone 5.3418020914 19584973
MESH:D016171 Torsades de Pointes Amiodarone 4.7317467628 11989578
MESH:D001749 Urinary Bladder Neoplasms decitabine 2.8317616700 19087683
MESH:D014604 Uveal Neoplasms decitabine 5.5217785578
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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