AutismKB 2.0

Annotation Detail for SLC12A1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SLC12A1 ( BSC1,MGC48843,NKCC2 )
Gene Full Name: solute carrier family 12 (sodium/potassium/chloride transporters), member 1
Band: 15q21.1
Quick LinksEntrez ID:6557; OMIM: 600839; Uniprot ID:S12A1_HUMAN; ENSEMBL ID: ENSG00000074803; HGNC ID: 10910
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Transmembrane transport of small molecules
No data
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1790Hyperaldosteronism
Desease Name
CARDIOVASCULAR
hypertension
No data
Desease Name
Bartter syndrome, type 1
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D001761 Bleomycin Bleomycin results in increased expression of SLC12A1 mRNAincreases expression 15808516
D002211 Capsaicin [Capsaicin co-treated with Sodium Chloride, Dietary] results in increased expression of SLC12A1 mRNAaffects cotreatment|increases expression 17414671
D002211 Capsaicin Capsaicin results in increased expression of SLC12A1 mRNAincreases expression 17414671
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of SLC12A1 mRNAdecreases expression 17805973
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of SLC12A1 mRNAincreases expression 16644059
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of SLC12A1 proteinincreases expression 15673309
16192424
D002712 Chlorides SLC12A1 protein alternative form affects the transport of [Sodium co-treated with Chlorides]affects cotreatment|affects transport 11249848
D005665 Furosemide Furosemide results in decreased activity of SLC12A1 proteindecreases activity 11249848
D005665 Furosemide Furosemide results in decreased activity of SLC12A1 proteindecreases activity 15976003
D005839 Gentamicins Gentamicins results in decreased expression of SLC12A1 proteindecreases expression 16850027
C029424 hydrazine hydrazine results in decreased expression of SLC12A1 mRNAdecreases expression 15282401
D007213 Indomethacin Indomethacin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SLC12A1 mRNA]decreases reaction|increases expression 18617548
D007213 Indomethacin Indomethacin results in increased expression of SLC12A1 proteinincreases expression 15053815
D018021 Lithium Chloride Lithium Chloride results in decreased expression of SLC12A1 proteindecreases expression 19692487
D018021 Lithium Chloride PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of SLC12A1 protein]decreases expression|increases reaction 19692487
D012964 Sodium SLC12A1 protein alternative form affects the transport of [Sodium co-treated with Chlorides]affects cotreatment|affects transport 11249848
D012965 Sodium Chloride SLC12A1 protein affects the transport of Sodium Chlorideaffects transport 8617496
D017673 Sodium Chloride, Dietary [Capsaicin co-treated with Sodium Chloride, Dietary] results in increased expression of SLC12A1 mRNAaffects cotreatment|increases expression 17414671
D017673 Sodium Chloride, Dietary Sodium Chloride, Dietary results in increased expression of SLC12A1 mRNAincreases expression 17414671
D049993 Sodium Chloride Symporter Inhibitors Sodium Chloride Symporter Inhibitors affects the activity of SLC12A1 proteinaffects activity 8617496
D043343 Testosterone Propionate Testosterone Propionate results in increased expression of SLC12A1 mRNAincreases expression 15601916
D013749 Tetrachlorodibenzodioxin Indomethacin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SLC12A1 mRNA]decreases reaction|increases expression 18617548
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin affects the expression of SLC12A1 mRNAaffects expression 18606429
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Capsaicin 8.8618926900
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.8611752688 14514962 15322242
MESH:D058186 Acute Kidney Injury Capsaicin 9.4518460982
MESH:D058186 Acute Kidney Injury Gentamicins 9.4511274264
MESH:D055371 Acute Lung Injury Bleomycin 4.9217118201
MESH:D000230 Adenocarcinoma Indomethacin 2.7916537180
MESH:D000236 Adenoma Indomethacin 3.4711497255
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.4316835633
MESH:D000505 Alopecia Capsaicin 4.7517569567
MESH:D016301 Alveolar Bone Loss Indomethacin 5.4317225004
MESH:D000544 Alzheimer Disease Indomethacin 2.7117627676 15579461
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9711748828
MESH:D000860 Anoxia Bleomycin 5.4615782499
MESH:D001014 Aortic Aneurysm Indomethacin 4.8810231640
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 4.9110388637
MESH:D018771 Arthralgia Indomethacin 5.232160914
MESH:D001172 Arthritis, Rheumatoid Indomethacin 2.8311248219
MESH:D001477 Bartter Syndrome Indomethacin 5.0210684365
MESH:C537652 Bartter syndrome, antenatal type 1 marker/mechanism
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.0712125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.8515340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7815746008
MESH:D001919 Bradycardia Capsaicin 5.1118207255
MESH:D001929 Brain Edema Indomethacin 5.0911481608
MESH:D002545 Brain Ischemia Capsaicin 10.7819211983
MESH:D002545 Brain Ischemia Indomethacin 10.7812524144
MESH:D001943 Breast Neoplasms Indomethacin 2.1917401462
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.1920435547
MESH:D002056 Burns Indomethacin 4.7510459503
MESH:D002100 Cachexia Indomethacin 5.0615141370 16537180 15625704 11239499
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.8216050911 18705752 3786805 16011737 15673190 16124888 16227642 10355542 15700767 16097048 16192424 15721981
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8216835633
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 3.2518788625
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 3.2516391822
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 4.7811053908
MESH:D018276 Carcinoma, Medullary Indomethacin 5.4018791128 11352223 14736730
MESH:D002292 Carcinoma, Renal Cell Indomethacin 3.3817341418
MESH:D002294 Carcinoma, Squamous Cell Bleomycin 5.376189445
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 5.3712636206 15482327
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3816120746 18670907 18850075
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1916835633
MESH:D002764 Cholecystitis Indomethacin 5.2311181007
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.118697196 15668235 16354765 12621046 15340226
MESH:D003110 Colonic Neoplasms Indomethacin 2.5915637740 15786552 15936596 15625704 11260862 15963497
MESH:D015179 Colorectal Neoplasms Indomethacin 2.3611197048 12606626 18059344 17054584
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0814669216 17141729
MESH:D018352 Coronavirus Infections Indomethacin 5.7817302372
MESH:D003371 Cough Capsaicin 5.2410350223
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2520055451 10048152 15322242
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6717107852
MESH:D003967 Diarrhea Indomethacin 3.837237001 7907874
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 3.7519085960 7120509 9327722 19336974 16227642 6623471 4309450 15998439 11566570 3786805 7440962 7179309 15968718 21278145 16177239 15027814 17522070 3732212 2869522 6884620 10092053 10915739
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.7520420201
MESH:D004362 Drug Toxicity Gentamicins 8.4615033597 11033412
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 8.4611462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 5.2012774134 18043480 18446180 16133044 16326151 17190690
MESH:D004381 Duodenal Ulcer Capsaicin 9.7811535926 10671773
MESH:D004381 Duodenal Ulcer Indomethacin 9.7811991626 17202747 11595415 10671773 16699067 11595431 17351913 17329845 17151854 17045617 11535926
MESH:D004417 Dyspnea Furosemide 5.0016935035
MESH:D004487 Edema Bleomycin 16.8317118201
MESH:D004487 Edema Furosemide 16.8311834646
MESH:D004487 Edema Indomethacin 16.837990266 10653021 19703484 8985016 7907874 16100529 8273558
MESH:D004487 Edema Tetrachlorodibenzodioxin 16.8311000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.9618230668 16714409 15322242
MESH:D004715 Endometriosis Indomethacin 9.1615652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 9.1610568697 9294722
MESH:D019446 Endotoxemia Indomethacin 4.5518509659
MESH:D004751 Enteritis Indomethacin 4.8110567023 17763956 16328016
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 5.0217980183
MESH:D004802 Eosinophilia Indomethacin 4.0911298111
MESH:D004935 Esophageal Diseases Capsaicin 5.7519566590
MESH:D004938 Esophageal Neoplasms Indomethacin 2.8111005569
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.0311564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 3.2015959796 16239168 17595544 12631006 61145 12795759 19224547 16045604
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5011858732
MESH:D005334 Fever Indomethacin 4.1417627676 10431976 11852909
MESH:D005354 Fibrosarcoma Indomethacin 4.9410962813
MESH:D005355 Fibrosis Carbon Tetrachloride 15.0918705752
MESH:D005355 Fibrosis Indomethacin 15.0917994277
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 15.0920067830
MESH:D005499 Folliculitis Indomethacin 5.2311298111
MESH:D005756 Gastritis Indomethacin 4.8115046732
MESH:D005909 Glioblastoma Capsaicin 7.7918405923
MESH:D005909 Glioblastoma Indomethacin 7.7912870263
MESH:D005910 Glioma Indomethacin 3.2316487511 18371953
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 4.3111849393
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.6610696789
MESH:D006073 Gout Indomethacin 5.4011248219
MESH:D006258 Head and Neck Neoplasms Indomethacin 3.7615482327
MESH:D034381 Hearing Loss Furosemide 10.5717868369
MESH:D034381 Hearing Loss Gentamicins 10.5715968427 17868369 18024279 19130971
MESH:D006356 Heartburn Capsaicin 5.7519566590
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.3410048152 11294989
MESH:D006333 Heart Failure Furosemide 4.0816011733 12660669 16845234
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3611000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 4.6015633222
MESH:D006505 Hepatitis Carbon Tetrachloride 3.6319900420 19110552
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.7215135802
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.9315340226 12621046 16120746
MESH:D006689 Hodgkin Disease Bleomycin 4.3917606976 15147373 18501091
MESH:D006869 Hydronephrosis Lithium Chloride 13.2419797860
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 13.2415340226 16959395 8697196 18606429 16354765
MESH:D006930 Hyperalgesia Capsaicin 8.5017043245 17434803
MESH:D006930 Hyperalgesia Indomethacin 8.5012727271
MESH:D034321 Hyperamylasemia Indomethacin 5.7817883296
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.5816899240
MESH:D006934 Hypercalcemia Furosemide 5.1017652376
MESH:D053565 Hypercalciuria Furosemide 13.6217652376
MESH:D053565 Hypercalciuria Gentamicins 13.6217652376
MESH:D006940 Hyperemia Indomethacin 5.0612524144
MESH:D006949 Hyperlipidemias Indomethacin 4.1917546600
MESH:D006962 Hyperparathyroidism, Secondary Furosemide 5.9415086907
MESH:D006973 Hypertension Sodium Chloride 9.1411507004
MESH:D006973 Hypertension Sodium Chloride, Dietary 9.1418524855
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 9.1418850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.1315338365
MESH:D046110 Hypertension, Pregnancy-Induced Furosemide 5.3316612254
MESH:C537153 Hypomagnesemia primary Furosemide 5.7011041285
MESH:D007019 Hypoproteinemia Furosemide 5.9416096441
MESH:D007022 Hypotension Furosemide 4.6511041285
MESH:D007024 Hypotension, Orthostatic Furosemide 5.4815811171
MESH:D007077 Ileal Diseases Indomethacin 5.0910574470 18306037
MESH:D007079 Ileitis Indomethacin 5.4016133968 10647630 10651667
MESH:D007235 Infant, Premature, Diseases Indomethacin 5.4316133044
MESH:D007249 Inflammation Bleomycin 12.2217118201
MESH:D007249 Inflammation Capsaicin 12.2216956363
MESH:D007249 Inflammation Indomethacin 12.223291741 12568917 7812673
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 12.2212878042 12200463
MESH:D007410 Intestinal Diseases Indomethacin 4.3718236018 10210152 11686837 17329856 11855677 11713966 15831440 15610444 17994277
MESH:D019586 Intracranial Hypertension Indomethacin 5.4315241188
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.3616580747
MESH:D007579 Jejunal Diseases Indomethacin 5.0918306037 16133968 10574470
MESH:D007673 Kidney Cortex Necrosis Gentamicins 5.7918842672
MESH:D007674 Kidney Diseases Furosemide 10.5711041285
MESH:D007674 Kidney Diseases Gentamicins 10.5717934191 19349640 18289764
MESH:D007674 Kidney Diseases Indomethacin 10.5717190690
MESH:D007683 Kidney Tubular Necrosis, Acute Gentamicins 5.4411231351
MESH:D016773 Leishmaniasis, Cutaneous Gentamicins 14.4310219319
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 14.4312228301 10320625 11703811
MESH:D016773 Leishmaniasis, Cutaneous Sodium Chloride 14.439499605
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 3.9415631656 16572323 10785260
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 2.6418360721
MESH:D007964 Leukocytosis Indomethacin 5.4316537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.7817980183
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.7811479899
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 2.8221278145 17174718 17334410 17157831 11408273 16943688 16239168 11903743 16221502
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 3.5418210741 11481614 15876570 17698563 17944888 16638106 15673190 14724832 15057751 12389079 10355542 12898905 17761835 18054572 18429990 16011737 18279442 17714472 18187930 17557913 15362042 15959796 15730626 16097048 16116963 18472332 18481824 15650968 16192424 15893842 12586293 17869086 18418968 12649538 16248980 12609069 12445421 14716833 15338365 17481882 18317297 16033810 17631135 15052691 18205269 18251166 17525996 16015684 12632514 17976157 18705752 18376398 12667390 12445418 18156304 20821823 12958196 18412020 12632512 14512876 15996030 15931870 17805973 15370692 17766677 12666154 12741479 17823541 15123356 18263696 17721639 18420326 16027843 17922224 13678700 14748882 17708605 15818738 17640975 18472094 18339082 14716496 17565644 17900296 18166357 18277467 14620537 12546737 18006644 18395914 15925388 18395095 16136751
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 3.5418194892
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.5412878042
MESH:D008107 Liver Diseases Capsaicin 4.5216956363
MESH:D008107 Liver Diseases Carbon Tetrachloride 4.5217285989 16964402 15720792 16246199 15830285
MESH:D017093 Liver Failure Carbon Tetrachloride 4.2115123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.7216899240 14706259
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 4.4319294768
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 4.4316984957
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 5.8115583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 5.8112151625
MESH:D008175 Lung Neoplasms Bleomycin 3.656189445
MESH:D008175 Lung Neoplasms Indomethacin 3.6511497255 11053908 16537180
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.6519555203 11884234
MESH:D008545 Melanoma Bleomycin 3.2515577320
MESH:D008881 Migraine Disorders Indomethacin 3.6911903285
MESH:D009062 Mouth Neoplasms Indomethacin 4.0112636206
MESH:D009101 Multiple Myeloma Capsaicin 4.1717505005
MESH:D009137 Muscular Dystrophy, Animal Gentamicins 6.3418694830
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0412213967
MESH:D009362 Neoplasm Metastasis Indomethacin 3.1811053908 11239499 16537180
MESH:D009374 Neoplasms, Experimental Indomethacin 4.1815625704 10663608
MESH:D009397 Nephrocalcinosis Furosemide 5.9415086907
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.2514600291
MESH:D019636 Neurodegenerative Diseases Indomethacin 3.9612349958
MESH:D020078 Neurogenic Inflammation Capsaicin 5.1217961222
MESH:D053206 Nocturnal Enuresis Furosemide 5.9417945291
MESH:D009765 Obesity Capsaicin 3.3919056576
MESH:D007752 Obstetric Labor, Premature Indomethacin 5.236374098
MESH:D010003 Osteoarthritis Indomethacin 3.687009135
MESH:D010146 Pain Capsaicin 7.4719081190 17043245 18987195 16996476 17084039 17434803
MESH:D010146 Pain Indomethacin 7.4717627676 13679232 17440234 3291741
MESH:D010149 Pain, Postoperative Indomethacin 4.7412538197 18702446
MESH:D010195 Pancreatitis Indomethacin 3.9517883296 15028970
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.7816537180
MESH:D020734 Parkinsonian Disorders Indomethacin 4.1412349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.7811903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.3112520081
MESH:D010437 Peptic Ulcer Indomethacin 5.2011148446
MESH:D010518 Periodontitis Indomethacin 4.9817225004
MESH:D011014 Pneumonia Bleomycin 5.4618024389 17071938 16317386
MESH:D011141 Polyuria Furosemide 13.7317945291
MESH:D011141 Polyuria Lithium Chloride 13.7319692487
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5918163543
MESH:D047928 Premature Birth Indomethacin 5.1717000239
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.2411222880 11118676 11399792 11896295
MESH:D011507 Proteinuria Gentamicins 9.8515033597
MESH:D011507 Proteinuria Indomethacin 9.8511849393
MESH:D011654 Pulmonary Edema Bleomycin 5.3815808516
MESH:D011658 Pulmonary Fibrosis Bleomycin 3.8821435439 11554783 16314464 12624602 17177178 18008008 17434272 17241526 15322207 12574379 18162602 14609568 15541506 16115399
MESH:D051437 Renal Insufficiency Gentamicins 5.0415728788 17132701
MESH:D015427 Reperfusion Injury Capsaicin 7.4319211983 18460982
MESH:D015427 Reperfusion Injury Furosemide 7.4316526316
MESH:D012128 Respiratory Distress Syndrome, Adult Furosemide 4.6512394941 15912074 16096441
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8718990726
MESH:D012173 Retinitis Gentamicins 6.3418644591
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.0516192470
MESH:D013272 Stomach Diseases Indomethacin 4.4715038085 17160473 15472012 10192188 18545984 18209964 16184426 10215738 17207306 10486359 16113693 17638125 16280098
MESH:D013274 Stomach Neoplasms Furosemide 3.8117052386
MESH:D013274 Stomach Neoplasms Indomethacin 3.8115609394
MESH:D013274 Stomach Neoplasms Sodium Chloride 3.8116646055
MESH:D013276 Stomach Ulcer Indomethacin 3.6118181030 18087811 18237397 16755016 1323529 12500499 18209962 10750652 17654042 10878458 12787963 15138204 15255614 16397915 11906479 12498302 11595431 17895592 17657623 17918041 16252198 18543354 11523592 11145282 16934674 14567935 16169175 12077510 18726076 15104355 18193104 11729361 10423059 17977527 12467913 16631530 18431645 18299717 16150113 11595415 17627676 17135157
MESH:D013705 Temporomandibular Joint Disorders Capsaicin 5.7917997062
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.9612697716
MESH:D013964 Thyroid Neoplasms Indomethacin 3.6014736730 11352223 18791128
MESH:D014456 Ulcer Indomethacin 4.9417380554 10574470
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.6612125929
MESH:D015837 Vestibular Diseases Gentamicins 5.5518776599
MESH:D014839 Vomiting Indomethacin 4.8111897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.3115886252
MESH:D015431 Weight Loss Bleomycin 5.6912624602
Pathway ID Pathway Name
REACT:15518 Transmembrane transport of small molecules
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA320
    • No data
    No data
    Releated drug ID Related drug Name
    PA448682bumetanide
    PA451733torasemide
    PA449719furosemide
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00214 antagonist Torasemide Antihypertensive Agents;Diuretics
    DB00232 antagonist Methyclothiazide Diuretics;Diuretics, Thiazide;Sodium Chloride Symporter Inhibitors
    DB00310 antagonist Tenoretic Antihypertensive Agents;Diuretics;Sodium Chloride Symporter Inhibitors
    DB00534 agonist Chlormerodrin Diagnostic aids;Mercurial Diuretics
    DB00695 blocker Furosemide Diuretics;Sodium Potassium Chloride Symporter Inhibitors
    DB00761 binder vivalmin 2 tab
    DB00774 antagonist Hydroflumethiazide Antihypertensive Agents;Diuretics;Diuretics, Thiazide;Sodium Chloride Symporter Inhibitors
    DB00887 antagonist Bumetanide Diuretics;Diuretics, Sulfamyl;Sodium Potassium Chloride Symporter Inhibitors
    DB00903 antagonist Ethacrynic acid Enzyme Inhibitors;Diuretics
    DB01021 antagonist Trichlormethiazide Antihypertensive Agents;Diuretics;Sodium Chloride Symporter Inhibitors
    DB01325 antagonist Hydromox R Antihypertensive Agents;Diuretics, Thiazide
    DB02925 blocker Piretanide Diuretics
    No data
    Drugbank ID Action Drug Name Description
    DB00761 substrate vivalmin 2 tab
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


    Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved