AutismKB 2.0

Annotation Detail for SLC16A1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SLC16A1 ( FLJ36745,HHF7,MCT,MCT1,MGC44475 )
Gene Full Name: solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
Band: 1p13.2
Quick LinksEntrez ID:6566; OMIM: 600682; Uniprot ID:MOT1_HUMAN; ENSEMBL ID: ENSG00000155380; HGNC ID: 10922
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Transmembrane transport of small molecules
Pyruvate metabolism and Citric Acid (TCA) cycle
Hemostasis
Bile salt and organic anion SLC transporters
No data
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1716Hypoglycemia
1848Embryoma
1856Obesity
1889Hyperinsulinism
1904Diabetes mellitus
1911Intestinal disease
1944Breast cancer
2204Hemolytic anemia
2239Lymphoma
No data
No data
Desease Name
Hyperinsulinemic hypoglycemia, familial, 7
Erythrocyte lactate transporter defect
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of SLC16A1 mRNAincreases expression 18648102
C002202 4-oxoretinoic acid 4-oxoretinoic acid results in decreased expression of SLC16A1 mRNAdecreases expression 15982314
C058176 5-nitro-2-(3-phenylpropylamino)benzoic acid 5-nitro-2-(3-phenylpropylamino)benzoic acid inhibits the reaction [SLC16A1 protein results in increased uptake of Butyrates]decreases reaction|increases uptake 19023563
D000079 Acetaldehyde Acetaldehyde inhibits the reaction [SLC16A1 protein results in increased uptake of Butyrates]decreases reaction|increases uptake 19023563
D000082 Acetaminophen Acetaminophen affects the expression of SLC16A1 mRNAaffects expression 17562736
D000085 Acetates Acetates inhibits the reaction [SLC16A1 protein results in increased uptake of Butyrates]decreases reaction|increases uptake 19023563
C000188 alachlor alachlor results in increased expression of SLC16A1 mRNAincreases expression 12419858
C103303 alitretinoin alitretinoin results in decreased expression of SLC16A1 mRNAdecreases expression 15982314
C040534 alpha-hexachlorocyclohexane alpha-hexachlorocyclohexane affects the expression of SLC16A1 mRNAaffects expression 16940010
C040534 alpha-hexachlorocyclohexane alpha-hexachlorocyclohexane results in decreased expression of SLC16A1 mRNAdecreases expression 16940010
C040534 alpha-hexachlorocyclohexane alpha-hexachlorocyclohexane results in increased expression of SLC16A1 mRNAincreases expression 16940010
C005087 alpha-ketobutyric acid alpha-ketobutyric acid inhibits the reaction [SLC16A1 protein results in increased uptake of Butyrates]decreases reaction|increases uptake 19023563
D000643 Ammonium Chloride Ammonium Chloride affects the expression of SLC16A1 mRNAaffects expression 16483693
D047310 Apigenin [Apigenin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybatedecreases activity|decreases uptake 17108059
D001241 Aspirin Aspirin affects the reaction [SLC16A1 protein results in increased uptake of Butyrates]affects reaction|increases uptake 19023563
D001241 Aspirin Aspirin results in decreased expression of SLC16A1 mRNAdecreases expression 11906190
D001554 Benzene [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in decreased expression of SLC16A1 mRNAaffects cotreatment|decreases expression 17905399
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SLC16A1 mRNAaffects cotreatment|decreases expression 18164116
D019817 Benzoic Acid morin inhibits the reaction [SLC16A1 protein results in increased uptake of Benzoic Acid]decreases reaction|increases uptake 17976262
D019817 Benzoic Acid naringenin inhibits the reaction [SLC16A1 protein results in increased uptake of Benzoic Acid]decreases reaction|increases uptake 17976262
D019817 Benzoic Acid Quercetin inhibits the reaction [SLC16A1 protein results in increased uptake of Benzoic Acid]decreases reaction|increases uptake 17976262
D019817 Benzoic Acid silybin inhibits the reaction [SLC16A1 protein results in increased uptake of Benzoic Acid]decreases reaction|increases uptake 17976262
D019817 Benzoic Acid SLC16A1 protein results in increased uptake of Benzoic Acidincreases uptake 17976262
C004541 biochanin A [biochanin A results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybatedecreases activity|decreases uptake 17108059
C006780 bisphenol A bisphenol A results in decreased expression of SLC16A1 mRNAdecreases expression 20678512
C006780 bisphenol A bisphenol A results in increased expression of SLC16A1 mRNAincreases expression 15901920
D002087 Butyrates 5-nitro-2-(3-phenylpropylamino)benzoic acid inhibits the reaction [SLC16A1 protein results in increased uptake of Butyrates]decreases reaction|increases uptake 19023563
D002087 Butyrates Acetaldehyde inhibits the reaction [SLC16A1 protein results in increased uptake of Butyrates]decreases reaction|increases uptake 19023563
D002087 Butyrates Acetates inhibits the reaction [SLC16A1 protein results in increased uptake of Butyrates]decreases reaction|increases uptake 19023563
D002087 Butyrates alpha-ketobutyric acid inhibits the reaction [SLC16A1 protein results in increased uptake of Butyrates]decreases reaction|increases uptake 19023563
D002087 Butyrates Aspirin affects the reaction [SLC16A1 protein results in increased uptake of Butyrates]affects reaction|increases uptake 19023563
D002087 Butyrates Caffeine affects the reaction [SLC16A1 protein results in increased uptake of Butyrates]affects reaction|increases uptake 19023563
D002087 Butyrates Indomethacin inhibits the reaction [SLC16A1 protein results in increased uptake of Butyrates]decreases reaction|increases uptake 19023563
D002087 Butyrates Lactic Acid inhibits the reaction [SLC16A1 protein results in increased uptake of Butyrates]decreases reaction|increases uptake 19023563
D002087 Butyrates N-Methyl-3,4-methylenedioxyamphetamine affects the reaction [SLC16A1 protein results in increased uptake of Butyrates]affects reaction|increases uptake 19023563
D002087 Butyrates p-Chloromercuribenzoic Acid inhibits the reaction [SLC16A1 protein results in increased uptake of Butyrates]decreases reaction|increases uptake 19023563
D002087 Butyrates Propionates inhibits the reaction [SLC16A1 protein results in increased uptake of Butyrates]decreases reaction|increases uptake 19023563
D002087 Butyrates Pyruvic Acid inhibits the reaction [SLC16A1 protein results in increased uptake of Butyrates]decreases reaction|increases uptake 19023563
D002087 Butyrates SLC16A1 protein results in increased uptake of Butyratesincreases uptake 19023563
D002087 Butyrates Tetrahydrocannabinol inhibits the reaction [SLC16A1 protein results in increased uptake of Butyrates]decreases reaction|increases uptake 19023563
D002087 Butyrates Theophylline inhibits the reaction [SLC16A1 protein results in increased uptake of Butyrates]decreases reaction|increases uptake 19023563
D002087 Butyrates SLC16A1 protein results in increased transport of Butyratesincreases transport 16042588
11953883
D002110 Caffeine Caffeine affects the reaction [SLC16A1 protein results in increased uptake of Butyrates]affects reaction|increases uptake 19023563
D002110 Caffeine Caffeine results in increased expression of SLC16A1 mRNAincreases expression 19023563
D002713 Chlorine [Ozone co-treated with Chlorine] results in increased expression of SLC16A1 mRNAaffects cotreatment|increases expression 18636392
D020245 p-Chloromercuribenzoic Acid p-Chloromercuribenzoic Acid inhibits the reaction [SLC16A1 protein results in increased uptake of Butyrates]decreases reaction|increases uptake 19023563
C043561 chrysin [chrysin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybatedecreases activity|decreases uptake 17108059
C019304 ciprofibrate ciprofibrate results in increased expression of SLC16A1 mRNAincreases expression 12771043
D002994 Clofibrate [Clofibrate results in increased activity of PPARA protein] which results in increased expression of SLC16A1 mRNAincreases activity|increases expression 18375207
D003513 Cycloheximide [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SLC16A1 mRNAaffects cotreatment|increases expression 19684285
D016572 Cyclosporine Cyclosporine results in increased expression of SLC16A1 mRNAincreases expression 20106945
C014347 decitabine decitabine affects the methylation of SLC16A1 geneaffects methylation 17630775
C014347 decitabine [decitabine co-treated with trichostatin A] results in increased expression of SLC16A1 mRNAaffects cotreatment|increases expression 20678512
C014347 decitabine decitabine results in increased expression of SLC16A1 mRNAincreases expression 20678512
D013759 Tetrahydrocannabinol Tetrahydrocannabinol inhibits the reaction [SLC16A1 protein results in increased uptake of Butyrates]decreases reaction|increases uptake 19023563
D013759 Tetrahydrocannabinol Tetrahydrocannabinol results in increased expression of SLC16A1 mRNAincreases expression 19023563
D004041 Dietary Fats Dietary Fats results in increased expression of SLC16A1 mRNAincreases expression 18042831
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of SLC16A1 mRNAincreases expression 12771043
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SLC16A1 mRNAaffects cotreatment|decreases expression 18164116
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of SLC16A1 mRNAincreases expression 19638242
C039602 diosmetin [diosmetin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybatedecreases activity|decreases uptake 17108059
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of SLC16A1 mRNAaffects cotreatment|decreases expression 19619570
D004958 Estradiol Estradiol results in increased expression of SLC16A1 mRNAincreases expression 19619570
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of SLC16A1 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of SLC16A1 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SLC16A1 mRNAaffects cotreatment|increases expression 17942748
C017875 fisetin [fisetin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybatedecreases activity|decreases uptake 17108059
D005472 Fluorouracil Fluorouracil results in decreased expression of SLC16A1 mRNAdecreases expression 16709241
D019833 Genistein [Genistein results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybatedecreases activity|decreases uptake 17108059
D019833 Genistein Genistein results in increased expression of SLC16A1 mRNAincreases expression 15901920
C013015 hesperetin [hesperetin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybatedecreases activity|decreases uptake 17108059
D012978 Sodium Oxybate [Apigenin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybatedecreases activity|decreases uptake 17108059
D012978 Sodium Oxybate [biochanin A results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybatedecreases activity|decreases uptake 17108059
D012978 Sodium Oxybate [chrysin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybatedecreases activity|decreases uptake 17108059
D012978 Sodium Oxybate [diosmetin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybatedecreases activity|decreases uptake 17108059
D012978 Sodium Oxybate [fisetin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybatedecreases activity|decreases uptake 17108059
D012978 Sodium Oxybate [Genistein results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybatedecreases activity|decreases uptake 17108059
D012978 Sodium Oxybate [hesperetin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybatedecreases activity|decreases uptake 17108059
D012978 Sodium Oxybate [kaempferol results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybatedecreases activity|decreases uptake 17108059
D012978 Sodium Oxybate [[Luteolin co-treated with Phloretin] results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybateaffects cotreatment|decreases activity|decreases uptake 17108059
D012978 Sodium Oxybate [Luteolin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybatedecreases activity|decreases uptake 17108059
D012978 Sodium Oxybate [morin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybatedecreases activity|decreases uptake 17108059
D012978 Sodium Oxybate [naringenin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybatedecreases activity|decreases uptake 17108059
D012978 Sodium Oxybate [Phloretin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybatedecreases activity|decreases uptake 17108059
D012978 Sodium Oxybate [Quercetin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybatedecreases activity|decreases uptake 17108059
D007213 Indomethacin Indomethacin inhibits the reaction [SLC16A1 protein results in increased uptake of Butyrates]decreases reaction|increases uptake 19023563
D007213 Indomethacin Indomethacin results in decreased expression of SLC16A1 mRNAdecreases expression 16984733
C006552 kaempferol [kaempferol results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybatedecreases activity|decreases uptake 17108059
D007657 Ketone Bodies Ketone Bodies results in decreased expression of SLC16A1 mRNAdecreases expression 16807920
D007657 Ketone Bodies Ketone Bodies results in increased expression of SLC16A1 mRNAincreases expression 15469884
D019344 Lactic Acid Lactic Acid inhibits the reaction [SLC16A1 protein results in increased uptake of Butyrates]decreases reaction|increases uptake 19023563
D019344 Lactic Acid SLC16A1 protein results in increased uptake of Lactic Acidincreases uptake 11785685
D047311 Luteolin [[Luteolin co-treated with Phloretin] results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybateaffects cotreatment|decreases activity|decreases uptake 17108059
D047311 Luteolin [Luteolin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybatedecreases activity|decreases uptake 17108059
C030957 methylmercury II [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in decreased expression of SLC16A1 mRNAaffects cotreatment|decreases expression 17905399
D018817 N-Methyl-3,4-methylenedioxyamphetamine N-Methyl-3,4-methylenedioxyamphetamine affects the reaction [SLC16A1 protein results in increased uptake of Butyrates]affects reaction|increases uptake 19023563
D018817 N-Methyl-3,4-methylenedioxyamphetamine N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of SLC16A1 mRNAincreases expression 19023563
C008548 morin morin inhibits the reaction [SLC16A1 protein results in increased uptake of Benzoic Acid]decreases reaction|increases uptake 17976262
C008548 morin [morin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybatedecreases activity|decreases uptake 17108059
D009151 Mustard Gas Mustard Gas affects the expression of SLC16A1 mRNAaffects expression 15651846
C005273 naringenin naringenin inhibits the reaction [SLC16A1 protein results in increased uptake of Benzoic Acid]decreases reaction|increases uptake 17976262
C005273 naringenin [naringenin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybatedecreases activity|decreases uptake 17108059
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in increased expression of SLC16A1 mRNAincreases expression 17616710
D010126 Ozone [Ozone co-treated with Chlorine] results in increased expression of SLC16A1 mRNAaffects cotreatment|increases expression 18636392
C041786 palm oil palm oil results in increased expression of SLC16A1 mRNAincreases expression 18042831
C076994 perfluorooctane sulfonic acid perfluorooctane sulfonic acid results in increased expression of SLC16A1 mRNAincreases expression 17560707
D010693 Phloretin [[Luteolin co-treated with Phloretin] results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybateaffects cotreatment|decreases activity|decreases uptake 17108059
D010693 Phloretin [Phloretin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybatedecreases activity|decreases uptake 17108059
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of SLC16A1 mRNAaffects binding|increases activity|increases expression 19710929
C006253 pirinixic acid pirinixic acid results in increased expression of SLC16A1 mRNAincreases expression 18301758
20059764
18445702
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in increased expression of SLC16A1 mRNA]increases expression|increases reaction 20059764
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of SLC16A1 mRNAaffects binding|increases activity|increases expression 18375207
D011422 Propionates Propionates inhibits the reaction [SLC16A1 protein results in increased uptake of Butyrates]decreases reaction|increases uptake 19023563
D019289 Pyruvic Acid Pyruvic Acid inhibits the reaction [SLC16A1 protein results in increased uptake of Butyrates]decreases reaction|increases uptake 19023563
D011794 Quercetin Quercetin inhibits the reaction [SLC16A1 protein results in increased uptake of Benzoic Acid]decreases reaction|increases uptake 17976262
D011794 Quercetin [Quercetin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybatedecreases activity|decreases uptake 17108059
D015474 Isotretinoin Isotretinoin results in decreased expression of SLC16A1 mRNAdecreases expression 15982314
C440975 silybin silybin inhibits the reaction [SLC16A1 protein results in increased uptake of Benzoic Acid]decreases reaction|increases uptake 17976262
C017947 sodium arsenite sodium arsenite results in increased expression of SLC16A1 mRNAincreases expression 17879257
12760830
D013629 Tamoxifen Tamoxifen affects the expression of SLC16A1 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of SLC16A1 mRNAaffects cotreatment|decreases expression 19619570
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SLC16A1 mRNAaffects cotreatment|increases expression 19684285
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of SLC16A1 mRNAincreases expression 19619570
19684285
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SLC16A1 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of SLC16A1 mRNAdecreases expression 16054898
D013806 Theophylline Theophylline inhibits the reaction [SLC16A1 protein results in increased uptake of Butyrates]decreases reaction|increases uptake 19023563
C052342 topiramate topiramate results in increased expression of SLC16A1 mRNAincreases expression 16979414
D014212 Tretinoin Tretinoin metabolite results in decreased expression of SLC16A1 mRNAdecreases expression 15982314
D014241 Trichloroethylene [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in decreased expression of SLC16A1 mRNAaffects cotreatment|decreases expression 17905399
C012589 trichostatin A [decitabine co-treated with trichostatin A] results in increased expression of SLC16A1 mRNAaffects cotreatment|increases expression 20678512
C012589 trichostatin A trichostatin A results in increased expression of SLC16A1 mRNAincreases expression 20678512
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 3.8614745880
MESH:D000014 Abnormalities, Drug-Induced Isotretinoin 6.4718769834
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 6.4714514962 15322242 11752688
MESH:D000015 Abnormalities, Multiple Isotretinoin 4.3718769834
MESH:D000138 Acidosis Ammonium Chloride 8.9818287403
MESH:D000138 Acidosis Lactic Acid 8.9820872349 18406487
MESH:D017486 Acneiform Eruptions Isotretinoin 5.5916232082
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 9.7017505938
MESH:D000152 Acne Vulgaris Isotretinoin 9.7016185265 18769834
MESH:D055371 Acute Lung Injury Chlorine 7.0720601635
MESH:D055371 Acute Lung Injury pirinixic acid 7.0718653653
MESH:D000230 Adenocarcinoma Estradiol 11.0611473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 11.0614692618
MESH:D000230 Adenocarcinoma Fluorouracil 11.0617638652
MESH:D000230 Adenocarcinoma Genistein 11.0611473722
MESH:D000230 Adenocarcinoma Indomethacin 11.0616537180
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 12.443712494
MESH:D000236 Adenoma beta-Naphthoflavone 12.4419389873
MESH:D000236 Adenoma Diethylnitrosamine 12.4410737359 6695378
MESH:D000236 Adenoma Indomethacin 12.4411497255
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 13.3719052882 17162532 19061943 18056438 17620307 16434500
MESH:D018248 Adenoma, Liver Cell pirinixic acid 13.3716434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 13.3716835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.0115276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.2116712894 17306315
MESH:D000382 Agricultural Workers' Diseases alachlor 4.0011874814 14769641
MESH:D000437 Alcoholism topiramate 4.4917925516 19331489 18552399
MESH:D000505 Alopecia Tretinoin 3.0615955085
MESH:D016301 Alveolar Bone Loss Indomethacin 4.6817225004
MESH:D000544 Alzheimer Disease Indomethacin 3.7415579461 17627676
MESH:D000544 Alzheimer Disease Ozone 3.7415513908
MESH:D000690 Amyotrophic Lateral Sclerosis Tetrahydrocannabinol 4.3815204022
MESH:D000740 Anemia Fluorouracil 6.7116511603 15504547 17963324
MESH:D000740 Anemia Tetrachlorodibenzodioxin 6.7111748828
MESH:D000741 Anemia, Aplastic Benzene 3.8317661222 14761424 11369114
MESH:D000743 Anemia, Hemolytic Quercetin 3.6317084956
MESH:D000799 Angioedema Acetaminophen 3.1510982225
MESH:D000855 Anorexia N-Methyl-3,4-methylenedioxyamphetamine 4.7215146954
MESH:D001014 Aortic Aneurysm Indomethacin 4.2010231640
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 4.2110388637
MESH:D001161 Arteriosclerosis Dietary Fats 7.7115238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 7.7111256880
MESH:D018771 Arthralgia Indomethacin 4.482160914
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 5.6915885639
MESH:D001169 Arthritis, Experimental Tretinoin 5.6916412693
MESH:D001172 Arthritis, Rheumatoid Indomethacin 6.1811248219
MESH:D001172 Arthritis, Rheumatoid Ozone 6.1815570426
MESH:D001172 Arthritis, Rheumatoid Tretinoin 6.1816292516
MESH:D001249 Asthma Acetaldehyde 12.129600491
MESH:D001249 Asthma Mustard Gas 12.1210378619
MESH:D001249 Asthma Ozone 12.1217854713 16373670
MESH:D001249 Asthma Theophylline 12.1212113382 9701106
MESH:D001249 Asthma Tretinoin 12.1216456186
MESH:D055963 Asthma, Aspirin-Induced Aspirin 4.1320485159 12372130
MESH:D001260 Ataxia Telangiectasia Quercetin 4.3015336622
MESH:D050197 Atherosclerosis Tetrahydrocannabinol 4.0415815632
MESH:D001321 Autistic Disorder Acetaminophen 1.5318445737
MESH:D001327 Autoimmune Diseases Quercetin 3.7519761891
MESH:D001471 Barrett Esophagus Tretinoin 3.7516935849
MESH:D001477 Bartter Syndrome Indomethacin 4.3210684365
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.331440618 11289319
MESH:D001768 Blister Mustard Gas 4.4819167455
MESH:D001778 Blood Coagulation Disorders Clofibrate 16.9719483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 16.9719483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 16.9712125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 16.9716206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.1015340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.2915746008
MESH:D001855 Bone Marrow Diseases Benzene 4.5416183116
MESH:D001862 Bone Resorption bisphenol A 3.2511985600
MESH:D001929 Brain Edema Indomethacin 4.3311481608
MESH:D002545 Brain Ischemia Indomethacin 3.7412524144
MESH:D001932 Brain Neoplasms Aspirin 3.8315481559
MESH:D001943 Breast Neoplasms alitretinoin 17.1716344269
MESH:D001943 Breast Neoplasms Apigenin 17.1716541309 17132221
MESH:D001943 Breast Neoplasms Aspirin 17.1715161893
MESH:D001943 Breast Neoplasms Benzene 17.1711921183 17162533
MESH:D001943 Breast Neoplasms bisphenol A 17.1717123778
MESH:D001943 Breast Neoplasms decitabine 17.1718320071 19208741
MESH:D001943 Breast Neoplasms Dietary Fats 17.1720435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 17.1717474063
MESH:D001943 Breast Neoplasms Estradiol 17.1719861407 16675129 17261762 17289903 17018787 12948864 18497071 14630087
MESH:D001943 Breast Neoplasms Fluorouracil 17.1719217205 18357371 15136595 16110121 16595493 16557594 18608205
MESH:D001943 Breast Neoplasms Genistein 17.1716541309 16873071 17200150
MESH:D001943 Breast Neoplasms Indomethacin 17.1717401462
MESH:D001943 Breast Neoplasms kaempferol 17.1716756079
MESH:D001943 Breast Neoplasms Quercetin 17.1718628248
MESH:D001943 Breast Neoplasms Tamoxifen 17.1720065188 19142967 18629630 17440819 19155303 19221464 19289846 16202921 20135344 19115204 18855134 21152245 19410462 15668708 18821012 19189210 19059307 16873071 19487384 19189212 18425577 19200415 20390343 20544844 20859285 19084267 11161223 17893378 16273361 15565566 18351453 19011961 17049068 18815881 18997820 18984771 20005174 21138602 17242785 19244106 17261762 16818667 19288272 19103187 19066611
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 17.1720435547
MESH:D001943 Breast Neoplasms Tretinoin 17.1716873071 16443354 16166294
MESH:D001943 Breast Neoplasms Trichloroethylene 17.1715986119
MESH:D016535 Bronchial Hyperreactivity Ozone 3.1317626835 15516495 19059883 18315731 16777450 18417511 14754758
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.4815286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.2817687719 10378619
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 3.9116813970
MESH:D002056 Burns Indomethacin 4.0410459503
MESH:D002100 Cachexia Indomethacin 10.1415141370 11239499 15625704 16537180
MESH:D002100 Cachexia Ozone 10.1416183385
MESH:D002105 Cadmium Poisoning Quercetin 4.8516962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.7816111702
MESH:D002276 Carcinoid Tumor Fluorouracil 3.9816051944
MESH:D002277 Carcinoma Fluorouracil 6.3617121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 6.3616835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 3.8419066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.4716168501
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 25.117296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 25.113084413
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 25.1116807293 20007298 18691550 18210153 20101231 16878318 19107877 18506893 19919837 16569478 19208518 19052882 10737359 20727157 16830150 17978847 18494052 17173139 18665156 17138121 19519916 3084413 17055752 19171122 20084675 20214788 19335982 16288022 19394651 21159647 17162532 16935385 18978308 20935162 10672840 16779866 16540662 17761372 20432363 17428255 3581430 18788625 16681979 16328049 16698587 19539802 20512989 19822196 19383236 16502159 18056438 20514400 19418558 18393292 18785209 20524982 18971187 11831363 19701751
MESH:D006528 Carcinoma, Hepatocellular Estradiol 25.1116924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 25.1118930000 16332177 16799960 17045692 17088986 17971768
MESH:D006528 Carcinoma, Hepatocellular Genistein 25.1116924424
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 25.1116391822
MESH:D006528 Carcinoma, Hepatocellular morin 25.1119539802
MESH:D006528 Carcinoma, Hepatocellular Quercetin 25.1112508355 19519916
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 25.1117306315 15276417 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 25.1116924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 25.111917145
MESH:D002278 Carcinoma in Situ bisphenol A 4.3117123778
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 4.0511053908
MESH:D018276 Carcinoma, Medullary Indomethacin 4.6714736730 18791128 11352223
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.2917234771
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 8.657296757
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 8.6518695887
MESH:D002292 Carcinoma, Renal Cell Indomethacin 8.6517341418
MESH:D002294 Carcinoma, Squamous Cell decitabine 14.7019215824
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 14.7017066447 16757204 18986760 16280240
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 14.7015482327 12636206
MESH:D002294 Carcinoma, Squamous Cell Isotretinoin 14.7011237771
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 14.7018572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 14.7016051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.0217572228
MESH:D006332 Cardiomegaly Quercetin 5.4019794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 5.4018670907 18850075 16120746
MESH:D002310 Cardiomyopathy, Alcoholic Acetaldehyde 5.7910525098
MESH:D002318 Cardiovascular Diseases Genistein 6.2116332659
MESH:D002318 Cardiovascular Diseases kaempferol 6.2116756079
MESH:D002375 Catalepsy Tetrahydrocannabinol 5.0510318961
MESH:D002386 Cataract Acetaminophen 5.7610977129
MESH:D002386 Cataract Tretinoin 5.7617460283
MESH:D002471 Cell Transformation, Neoplastic marker/mechanism 11953883
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 19.977505956
MESH:D002471 Cell Transformation, Neoplastic Clofibrate 19.971399818
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 19.9712371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 19.972727394 7505956 17174075 21159647
MESH:D002471 Cell Transformation, Neoplastic Estradiol 19.9718566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 19.9719524636 20056578
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 3.9116129372
MESH:D002637 Chest Pain Theophylline 5.1815238202
MESH:D002659 Child Development Disorders, Pervasive topiramate 3.8015650499
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 7.3919052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 7.3916835633
MESH:D002764 Cholecystitis Indomethacin 4.4811181007
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 14.9319486331 9022650
MESH:D002779 Cholestasis Cyclosporine 14.9319486331
MESH:D002779 Cholestasis Ethinyl Estradiol 14.9317110522 16105132 15861022 17681005 11677210 16919318 17333356
MESH:D002779 Cholestasis pirinixic acid 14.9319176532
MESH:D002822 Choriocarcinoma Tretinoin 4.4716461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 4.6412621046 16354765 15668235 8697196 15340226
MESH:D002972 Cleft Palate Tretinoin 4.649407595
MESH:D003092 Colitis Tretinoin 3.0517035595
MESH:D003110 Colonic Neoplasms marker/mechanism 11953883
MESH:D003110 Colonic Neoplasms Aspirin 14.4312411196
MESH:D003110 Colonic Neoplasms Butyrates 14.4315936596
MESH:D003110 Colonic Neoplasms decitabine 14.4317616700
MESH:D003110 Colonic Neoplasms Fluorouracil 14.4317016597 15001691 17018589 16340194 17725105 17287894 16510598 17172411 17169374 18772588
MESH:D003110 Colonic Neoplasms Genistein 14.4317182828
MESH:D003110 Colonic Neoplasms Indomethacin 14.4315637740 15786552 15936596 11260862 15625704 15963497
MESH:D003110 Colonic Neoplasms Quercetin 14.4319056647 15741050 17191121 11134977 19440933 16640504 17148506
MESH:D015179 Colorectal Neoplasms Aspirin 5.4417047198
MESH:D015179 Colorectal Neoplasms decitabine 5.4418981723
MESH:D015179 Colorectal Neoplasms Fluorouracil 5.4417454858 16524972 17016601 18949393 18802399 18288408 18383874 16391804 15289873 18448328 17255274 16282729 17695437 16331619 20501625 15148649 17401013 17594712 14970324 17094418 16303861 18509181
MESH:D015179 Colorectal Neoplasms Indomethacin 5.4412606626 17054584 18059344 11197048
MESH:D015179 Colorectal Neoplasms Quercetin 5.4418095365 18852136
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.4814669216 17141729
MESH:D018352 Coronavirus Infections Indomethacin 5.0217302372
MESH:D019465 Craniofacial Abnormalities Benzene 4.5715643154
MESH:D019465 Craniofacial Abnormalities Isotretinoin 4.5718769834 9879862
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 4.5710048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Tretinoin 4.5717551590 9224671 9125849 9211117 10589399 16925845 14991402 9142499 8800419 9664655
MESH:D007644 Darier Disease Fluorouracil 4.1116733453
MESH:D003711 Demyelinating Diseases Tamoxifen 3.7019031437
MESH:D003872 Dermatitis Benzene 4.1015902427
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 5.2118759878 14531868 12868966 8156756 2524372 8970840 11298694 11906362
MESH:D017449 Dermatitis, Allergic Contact alachlor 5.218428444
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.0718249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 2.873621924 2952479
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.1719496084
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 8.4120387270
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 8.4116647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 8.4117107852
MESH:D003924 Diabetes Mellitus, Type 2 topiramate 8.4116979414
MESH:D003928 Diabetic Nephropathies Estradiol 6.9119279558
MESH:D003928 Diabetic Nephropathies Tamoxifen 6.9119279558
MESH:D003967 Diarrhea Indomethacin 3.177907874 7237001
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 9.229022650 6482804 18289764 18648102 8291058 6679447 18692083 16192314 9653073 9328219 7440962 11289319 1440618
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 9.2219370779 11287661 12540782 17906064 10774834 16081117 15619225 12705907 19164858 19739265 14550746 19416960 14986274 10663392 19085960 14725611 12958197 16109766 11834606 18071297 16177239 18713872 12153990 10915739 19420014 16781746 11529661 15968718 19923254 11461765 12594235 16393943 2444490 11739529 16227642 12392966 11743745 16485898 17522070 11421492 17562736
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 9.2219107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 9.2220420201
MESH:D056486 Drug-Induced Liver Injury Trichloroethylene 9.227120509
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.4119426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.2411462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 4.4718446180 16133044 16326151 18043480 17190690 12774134
MESH:D004381 Duodenal Ulcer Indomethacin 3.5011595415 10671773 17151854 11595431 17351913 17329845 11991626 17045617 16699067 11535926 17202747
MESH:D050171 Dyslipidemias Clofibrate 7.1116707586
MESH:D050171 Dyslipidemias Dietary Fats 7.1118367378
MESH:D004417 Dyspnea Chlorine 3.9420016425
MESH:D004487 Edema Aspirin 15.2917259670
MESH:D004487 Edema Indomethacin 15.298985016 10653021 16100529 19703484 7907874 8273558 7990266
MESH:D004487 Edema Mustard Gas 15.2911402378 11428647 11428631 9260866
MESH:D004487 Edema pirinixic acid 15.2912083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 15.2911000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 9.6518230668 16714409 15322242
MESH:D004489 Edema, Cardiac Tretinoin 9.6518230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 6.8112538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 6.8119031437
MESH:D004701 Endocrine Gland Neoplasms decitabine 11.7319294695
MESH:D004701 Endocrine Gland Neoplasms trichostatin A 11.7319294695
MESH:D004714 Endometrial Hyperplasia Genistein 3.9116402032
MESH:D016889 Endometrial Neoplasms Estradiol 13.8711473722 19148513 18566989
MESH:D016889 Endometrial Neoplasms Genistein 13.8711473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 13.8719155303 20544844 16202921 17893378
MESH:D016889 Endometrial Neoplasms Tretinoin 13.8716569247
MESH:D004715 Endometriosis Indomethacin 7.0915652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 7.099294722 10568697
MESH:D019446 Endotoxemia Indomethacin 3.8318509659
MESH:D004751 Enteritis Indomethacin 4.0610567023 17763956 16328016
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 4.3217980183
MESH:D004802 Eosinophilia Indomethacin 3.4011298111
MESH:D004827 Epilepsy Tetrahydrocannabinol 6.44821787
MESH:D004827 Epilepsy topiramate 6.4419148780
MESH:D004832 Epilepsy, Absence Sodium Oxybate 5.846254150
MESH:D004833 Epilepsy, Temporal Lobe topiramate 5.5816499746
MESH:D004890 Erythema Mustard Gas 4.489357497
OMIM:245340 ERYTHROCYTE LACTATE TRANSPORTER DEFECT marker/mechanism
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.4216302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 8.503581430
MESH:D004938 Esophageal Neoplasms Fluorouracil 8.5016785472 16481741 15173087 16337965 17638652
MESH:D004938 Esophageal Neoplasms Indomethacin 8.5011005569
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 8.5015150132 16805852 15547721 16510608 15623463 15878914 15264214 15547733 16704527
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.0811564622
MESH:D005124 Eye Abnormalities Tretinoin 7.089664655 16938888
MESH:D005234 Fatty Liver Clofibrate 27.6819224547
MESH:D005234 Fatty Liver Cyclosporine 27.6819224547
MESH:D005234 Fatty Liver Dietary Fats 27.6818296743 19004024 19551842 17967931
MESH:D005234 Fatty Liver Diethylnitrosamine 27.6820387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 27.6815345470
MESH:D005234 Fatty Liver pirinixic acid 27.6819236843 20131406
MESH:D005234 Fatty Liver Tamoxifen 27.6814986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 2.7916709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.8011858732
MESH:D005334 Fever Indomethacin 3.5317627676 11852909 10431976
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.336705139
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 3.8514745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.5019069698
MESH:D005354 Fibrosarcoma Indomethacin 4.2210962813
MESH:D005355 Fibrosis Cyclosporine 26.0012168785 12639820
MESH:D005355 Fibrosis Dietary Fats 26.0018296743
MESH:D005355 Fibrosis Indomethacin 26.0017994277
MESH:D005355 Fibrosis Quercetin 26.0019474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 26.0020067830
MESH:D005355 Fibrosis Tretinoin 26.0017994277
MESH:D005499 Folliculitis Indomethacin 4.4811298111
MESH:D005739 Gas Poisoning Chlorine 4.3220016425
MESH:D005756 Gastritis Acetaminophen 8.8516983495
MESH:D005756 Gastritis Indomethacin 8.8515046732
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.0016452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.548708960
MESH:D005909 Glioblastoma Aspirin 30.9612870263
MESH:D005909 Glioblastoma biochanin A 30.9616598420
MESH:D005909 Glioblastoma Genistein 30.9616598420
MESH:D005909 Glioblastoma Indomethacin 30.9612870263
MESH:D005909 Glioblastoma perfluorooctane sulfonic acid 30.9617162496
MESH:D005909 Glioblastoma Quercetin 30.9619804834
MESH:D005909 Glioblastoma Tretinoin 30.9617312396
MESH:D005909 Glioblastoma trichostatin A 30.9618801729
MESH:D005910 Glioma Fluorouracil 8.1016145905
MESH:D005910 Glioma Indomethacin 8.1018371953 16487511
MESH:D005910 Glioma Quercetin 8.1017643826
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 3.7311849393
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.417505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.9010696789
MESH:D006073 Gout Indomethacin 4.6711248219
MESH:D006261 Headache Aspirin 4.2715240983
MESH:D006258 Head and Neck Neoplasms decitabine 14.4719215824
MESH:D006258 Head and Neck Neoplasms Fluorouracil 14.4715162350 15102660 18337622
MESH:D006258 Head and Neck Neoplasms Indomethacin 14.4715482327
MESH:D006258 Head and Neck Neoplasms Tretinoin 14.4716096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.4716084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 5.1910048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 5.1914991402 9664655
MESH:D006333 Heart Failure pirinixic acid 2.0920558911
MESH:D006402 Hematologic Diseases Benzene 4.0216183116
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.7415720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.7211000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 3.9615633222
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 7.606705139
MESH:D006505 Hepatitis Caffeine 7.6011394713
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.0415135802
MESH:D006529 Hepatomegaly pirinixic acid 6.0816221962 19176532 18467677 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 6.0815340226 12621046 16120746
MESH:D006558 Herpes Genitalis Estradiol 4.3415709030
MESH:D006689 Hodgkin Disease sodium arsenite 2.6012676792
MESH:D019584 Hot Flashes Estradiol 3.0717088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.3516959395 15340226 16354765 18606429 8697196
MESH:D012001 Hyperacusis Aspirin 5.0715240983
MESH:D006930 Hyperalgesia Acetaminophen 9.9016870215
MESH:D006930 Hyperalgesia Indomethacin 9.9012727271
MESH:D006930 Hyperalgesia Tretinoin 9.9016870215
MESH:D034321 Hyperamylasemia Indomethacin 5.0217883296
MESH:D006937 Hypercholesterolemia Dietary Fats 2.9921332399
MESH:D006940 Hyperemia Indomethacin 4.3312524144
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 3.9016778211
MESH:D006943 Hyperglycemia kaempferol 12.3618262572
MESH:D006943 Hyperglycemia pirinixic acid 12.3620558911
MESH:D006943 Hyperglycemia Quercetin 12.3611834736 18262572
MESH:C538376 Hyperinsulinemic hypoglycemia, familial, 7 marker/mechanism
MESH:D006949 Hyperlipidemias Dietary Fats 7.2621332399
MESH:D006949 Hyperlipidemias Indomethacin 7.2617546600
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.2815034207
MESH:D006973 Hypertension Benzene 9.7817940673
MESH:D006973 Hypertension Cyclosporine 9.7810903974
MESH:D006973 Hypertension Quercetin 9.7818356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 9.7818850075 18670907
MESH:D007021 Hypospadias Ethinyl Estradiol 3.1516569931 16945680
MESH:D007035 Hypothermia Tetrahydrocannabinol 5.2710318961
MESH:D007077 Ileal Diseases Indomethacin 4.3318306037 10574470
MESH:D007079 Ileitis Indomethacin 4.6710651667 10647630 16133968
MESH:D007235 Infant, Premature, Diseases Indomethacin 4.6816133044
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.8312013081
MESH:D007248 Infertility, Male alachlor 16.0516466525 17049205 12948887
MESH:D007248 Infertility, Male decitabine 16.0517581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 16.0517937319
MESH:D007248 Infertility, Male sodium arsenite 16.0515346721 12646999
MESH:D007248 Infertility, Male Theophylline 16.0516988215
MESH:D007249 Inflammation Dietary Fats 14.7720412841
MESH:D007249 Inflammation Diethylnitrosamine 14.7718785209
MESH:D007249 Inflammation Indomethacin 14.777812673 3291741 12568917
MESH:D007249 Inflammation Mustard Gas 14.7716001271 9357497 11402378 17524151 11428631 11428620 9260866 8975870 11428647
MESH:D007249 Inflammation Tamoxifen 14.7719457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 14.7712200463 12878042
MESH:D007251 Influenza, Human Quercetin 3.8216624496
MESH:D007333 Insulin Resistance bisphenol A 13.7316393666
MESH:D007333 Insulin Resistance Dietary Fats 13.7318457598 11836018
MESH:D007333 Insulin Resistance Estradiol 13.7316393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 13.7316306350
MESH:D007410 Intestinal Diseases Indomethacin 7.6915610444 18236018 17329856 11686837 11713966 17994277 10210152 11855677 15831440
MESH:D007410 Intestinal Diseases Tretinoin 7.6917994277
MESH:D019586 Intracranial Hypertension Indomethacin 4.6815241188
MESH:D007511 Ischemia morin 5.2616806951
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.338074119 9022650
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 7.9016580747
MESH:D007569 Jaw Abnormalities Tretinoin 7.9015992940 17551590
MESH:D007579 Jejunal Diseases Indomethacin 4.3316133968 18306037 10574470
MESH:D007627 Keloid Quercetin 4.2917086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.7515604871
MESH:D017492 Keratosis, Seborrheic alitretinoin 4.9616144296
MESH:D007674 Kidney Diseases Acetaminophen 18.2715629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 18.2718776723 10903974 8314463
MESH:D007674 Kidney Diseases Estradiol 18.2715618244
MESH:D007674 Kidney Diseases Indomethacin 18.2717190690
MESH:D007674 Kidney Diseases Quercetin 18.2716962696
MESH:D007674 Kidney Diseases sodium arsenite 18.2720008137
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 17.416582329
MESH:D007680 Kidney Neoplasms Cyclosporine 17.4112371664
MESH:D007680 Kidney Neoplasms Estradiol 17.4115610895
MESH:D007680 Kidney Neoplasms Fluorouracil 17.4116985049
MESH:D007680 Kidney Neoplasms Tamoxifen 17.4118625569
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.3512228301 10320625 11703811
MESH:D007938 Leukemia alachlor 23.8214769641
MESH:D007938 Leukemia Benzene 23.8215935818 18335105 17119257 14694614
MESH:D007938 Leukemia decitabine 23.8219235587 18980019
MESH:D007938 Leukemia Genistein 23.8217468513 18980019
MESH:D007938 Leukemia kaempferol 23.8217468513
MESH:D007938 Leukemia Quercetin 23.8217468513
MESH:D007938 Leukemia Tretinoin 23.8217143497
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 3.4016572323 15631656 10785260
MESH:D007951 Leukemia, Myeloid Benzene 12.5417506065
MESH:D007951 Leukemia, Myeloid decitabine 12.5418454857 19117987 17236224
MESH:D007951 Leukemia, Myeloid Tretinoin 12.5416932348 16482212 19285840
MESH:D015470 Leukemia, Myeloid, Acute Benzene 9.7719478238
MESH:D015470 Leukemia, Myeloid, Acute decitabine 9.7718206229 17679729 19010910 18704418 19387464 18460780
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 9.7718360721
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 9.7717596541 16294345 19850784
MESH:D015470 Leukemia, Myeloid, Acute trichostatin A 9.7718206229
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 4.7718055864
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 2.6817339181 17368321 17361223 19225113 17649720 16331271 16935935 9834237 17301526 17217047 17294898 16140955 19075265 12679006 16823087 19035177 16891316 15748426 17107899 19642359 16788101 19029980 17506722 16766008 17712046
MESH:D007964 Leukocytosis Indomethacin 4.6816537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.0217980183
MESH:D017880 Limb Deformities, Congenital Tretinoin 2.809224671
MESH:D008064 Lipidoses Tamoxifen 2.6517567588 15342952
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.0211479899
MESH:D008103 Liver Cirrhosis Dietary Fats 5.2418296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 5.2418665156 20032147 18407596 18522880 19638242
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.7415034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 17.7514716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Genistein 17.7517823541
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 17.7518194892
MESH:D008106 Liver Cirrhosis, Experimental morin 17.7518629640
MESH:D008106 Liver Cirrhosis, Experimental naringenin 17.7514709902
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 17.7515474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 17.7512741479
MESH:D008106 Liver Cirrhosis, Experimental silybin 17.7516169303
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 17.7518564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 17.7512878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 17.7518397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 5.3616610002 16611625 19014921 12969438 19784758 12587719 19460945 11587558
MESH:D008107 Liver Diseases Diethylnitrosamine 5.3617034775
MESH:D008107 Liver Diseases naringenin 5.3616945181
MESH:D017114 Liver Failure, Acute Acetaminophen 2.6416871587 17185352
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 23.8219389873 21295105
MESH:D008113 Liver Neoplasms ciprofibrate 23.8212771043
MESH:D008113 Liver Neoplasms Diethylnitrosamine 23.8219427195 15885732 21278145 19254457 16942905 20434301 19256749 21047994 18754104 2862719 12771043 2422723 12112319 18978307 20137499 19996281 19638242 20405173 19294768 21071580 18644402 19850985 19690152 21167192 19499222 10737359 19426721 19255062 19812893 20101389 19833225 20118626 20452335 19642983 18977376 19090486 9163691 15175105 19073162 20492335 19551842 20501860 18648771 20583210
MESH:D008113 Liver Neoplasms Fluorouracil 23.8215113037 16603448 17045692 18383874
MESH:D008113 Liver Neoplasms pirinixic acid 23.8220007298 16377806 15890375
MESH:D008113 Liver Neoplasms Quercetin 23.8218980244
MESH:D008113 Liver Neoplasms sodium arsenite 23.8215276417 16712894
MESH:D008113 Liver Neoplasms Tamoxifen 23.8216684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 23.8216984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 25.233712494 598648 1399818 6587162
MESH:D008114 Liver Neoplasms, Experimental Benzene 25.2312562636
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 25.2318164116
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 25.233124819 19009564 21159647 18775883 18282651 19539802 16842330 18253720 17174075 18164116 17854601 16267830 9362446 18544905 2563599 19126423 19519916 18079962 19004024 18093689 17942915 18308698
MESH:D008114 Liver Neoplasms, Experimental morin 25.2319539802
MESH:D008114 Liver Neoplasms, Experimental Quercetin 25.2319519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 25.2312151625
MESH:D008114 Liver Neoplasms, Experimental Trichloroethylene 25.237955063
MESH:D008171 Lung Diseases Mustard Gas 9.5918161513 18702808
MESH:D008171 Lung Diseases Ozone 9.598266340 19066396
MESH:D008171 Lung Diseases sodium arsenite 9.5919095001
MESH:D017563 Lung Diseases, Interstitial Benzene 4.1214698565
MESH:D055370 Lung Injury Ozone 3.2020417186
MESH:D008175 Lung Neoplasms Acetaldehyde 24.9717372256
MESH:D008175 Lung Neoplasms alitretinoin 24.9716413115
MESH:D008175 Lung Neoplasms Benzene 24.9712562636
MESH:D008175 Lung Neoplasms Diethylnitrosamine 24.976695378 21163286 20512841 20970405
MESH:D008175 Lung Neoplasms Fluorouracil 24.9715246190
MESH:D008175 Lung Neoplasms Indomethacin 24.9711497255 11053908 16537180
MESH:D008175 Lung Neoplasms Isotretinoin 24.9715899809
MESH:D008175 Lung Neoplasms Mustard Gas 24.973148597 8781369
MESH:D008175 Lung Neoplasms Ozone 24.978597069 7614698
MESH:D008175 Lung Neoplasms Quercetin 24.9716280456
MESH:D008175 Lung Neoplasms silybin 24.9716788158
MESH:D008175 Lung Neoplasms sodium arsenite 24.9715276417 17077188 17306315 16712894 19931552
MESH:D008175 Lung Neoplasms Tamoxifen 24.9718625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 24.9711884234 19555203
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.1115086387
MESH:D008223 Lymphoma Benzene 6.1417119257 17584886
MESH:D008223 Lymphoma decitabine 6.1419470736
MESH:D015674 Mammary Neoplasms, Animal Benzene 7.8312562636
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 7.8319428831
MESH:D008325 Mammary Neoplasms, Experimental Benzene 10.4611921183
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 10.4611408345 16891317 17203775 11807958
MESH:D008325 Mammary Neoplasms, Experimental Genistein 10.4614578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 10.4616827153 11731420 19196723 14580682 19196722
MESH:D020149 Manganese Poisoning Estradiol 10.3519453300
MESH:D020149 Manganese Poisoning Tamoxifen 10.3519453300
MESH:D008527 Medulloblastoma Tretinoin 2.4717453147
MESH:D008545 Melanoma decitabine 10.2316505122 17785578
MESH:D008545 Melanoma Isotretinoin 10.2317237267
MESH:D008545 Melanoma sodium arsenite 10.2319082730 16487513
MESH:D008545 Melanoma Tamoxifen 10.2312393984 19393235
MESH:D008545 Melanoma Tretinoin 10.2316752155
MESH:D008545 Melanoma trichostatin A 10.2316505122
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.5015990972
MESH:D008546 Melanoma, Experimental Acetaminophen 2.9119513568
MESH:D008591 Meningomyelocele Tretinoin 3.7616940565
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.0916801185
MESH:D008679 Metaplasia Ozone 4.4110496685
MESH:D008881 Migraine Disorders Aspirin 9.9615240983
MESH:D008881 Migraine Disorders Indomethacin 9.9611903285
MESH:D008881 Migraine Disorders topiramate 9.9618803445 18765137 18759728 16942474
MESH:D009062 Mouth Neoplasms Fluorouracil 7.0416757204 18986760
MESH:D009062 Mouth Neoplasms Indomethacin 7.0412636206
MESH:D009101 Multiple Myeloma alachlor 13.2214769641
MESH:D009101 Multiple Myeloma Benzene 13.2217119195
MESH:D009101 Multiple Myeloma decitabine 13.2218172295
MESH:D009101 Multiple Myeloma trichostatin A 13.2218172295
MESH:D009135 Muscular Diseases pirinixic acid 2.8516239165
MESH:D009190 Myelodysplastic Syndromes decitabine 6.0419010910 18608210 19157545 16882708
MESH:D009190 Myelodysplastic Syndromes Tretinoin 6.0417596541
MESH:D009203 Myocardial Infarction Aspirin 10.8012692751
MESH:D009203 Myocardial Infarction Genistein 10.8017141266
MESH:D009203 Myocardial Infarction pirinixic acid 10.8019151258
MESH:D009203 Myocardial Infarction Quercetin 10.8019595682
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.4712213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 15.8916810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 15.8917141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 15.8916411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 15.8919207477
MESH:D009325 Nausea Aspirin 4.5215240983
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 10.883581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 10.883581430 9029167
MESH:D009362 Neoplasm Metastasis Indomethacin 10.8811053908 11239499 16537180
MESH:D009362 Neoplasm Metastasis Tamoxifen 10.8819393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.2519410462
MESH:D009369 Neoplasms alitretinoin 25.2416946489
MESH:D009369 Neoplasms decitabine 25.2417925555 19116145 19470736
MESH:D009369 Neoplasms Fluorouracil 25.2418239605 18600527 16928823
MESH:D009369 Neoplasms naringenin 25.2415185748
MESH:D009369 Neoplasms pirinixic acid 25.2417405874
MESH:D009369 Neoplasms Quercetin 25.2415185748
MESH:D009369 Neoplasms sodium arsenite 25.2411559025
MESH:D009369 Neoplasms Tretinoin 25.2416946489 16594593
MESH:D009369 Neoplasms Trichloroethylene 25.2411911487
MESH:D009374 Neoplasms, Experimental Indomethacin 7.0910663608 15625704
MESH:D009374 Neoplasms, Experimental sodium arsenite 7.0920056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.3119196722 19200415 19189210
MESH:D009389 Neovascularization, Pathologic Estradiol 3.0617289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.7517954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 2.7018481113 19348381
MESH:D009421 Nervous System Malformations bisphenol A 23.9416427766 11399458
MESH:D009421 Nervous System Malformations Estradiol 23.9411399458 16427766
MESH:D009421 Nervous System Malformations Genistein 23.9416427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 23.9414600291
MESH:D009421 Nervous System Malformations Tretinoin 23.949125849
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 17.776679447
MESH:D009436 Neural Tube Defects Benzene 17.7715643154
MESH:D009436 Neural Tube Defects sodium arsenite 17.7712854658
MESH:D009436 Neural Tube Defects Tetrahydrocannabinol 17.7719040278
MESH:D009436 Neural Tube Defects Tretinoin 17.779142499
MESH:D009447 Neuroblastoma Isotretinoin 3.6517368321
MESH:D019636 Neurodegenerative Diseases Acetaminophen 10.8118514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 10.8120387270
MESH:D019636 Neurodegenerative Diseases Indomethacin 10.8112349958
MESH:D020078 Neurogenic Inflammation Quercetin 3.7317929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.4220387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 2.9516436463
MESH:D009503 Neutropenia Mustard Gas 3.3516761898 7688884
MESH:D052556 Niemann-Pick Disease, Type C Clofibrate 4.279802331
MESH:D009669 Nose Neoplasms alachlor 4.1514563481 15580706 16698726 11127290 16178123
MESH:D009765 Obesity Dietary Fats 3.6916723640 18674790 20518802 21332399 11836018 19632207 18457598 17217161 20132043
MESH:D009765 Obesity pirinixic acid 3.6920558911
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.486374098
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 7.184026338 6482804
MESH:D009784 Occupational Diseases Benzene 7.1815612468 15576619 15935809 17119257 17479406 15727169 15913788 17178637 16737584
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.333988306
MESH:D010003 Osteoarthritis Aspirin 6.527009135
MESH:D010003 Osteoarthritis Indomethacin 6.527009135
MESH:D010024 Osteoporosis Genistein 6.1719401787
MESH:D010024 Osteoporosis kaempferol 6.1716756079
MESH:D015663 Osteoporosis, Postmenopausal Genistein 8.0516169203
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 8.0519495926
MESH:D010049 Ovarian Diseases bisphenol A 4.3111985600
MESH:D010051 Ovarian Neoplasms Benzene 26.0212562636
MESH:D010051 Ovarian Neoplasms decitabine 26.0219259094 19331143
MESH:D010051 Ovarian Neoplasms Estradiol 26.0219401270
MESH:D010051 Ovarian Neoplasms Genistein 26.0219005980
MESH:D010051 Ovarian Neoplasms Luteolin 26.0219005980
MESH:D010051 Ovarian Neoplasms Quercetin 26.0219005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 26.0215276417 17306315
MESH:D010051 Ovarian Neoplasms Tretinoin 26.0216936753
MESH:D010051 Ovarian Neoplasms trichostatin A 26.0219331143
MESH:D010146 Pain Acetaminophen 11.5916870215
MESH:D010146 Pain Aspirin 11.596363464 6995502
MESH:D010146 Pain Indomethacin 11.5917627676 3291741 17440234 13679232
MESH:D010146 Pain Tretinoin 11.5916870215
MESH:D010149 Pain, Postoperative Indomethacin 3.9918702446 12538197
MESH:D010190 Pancreatic Neoplasms decitabine 16.5619294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 16.5616540662
MESH:D010190 Pancreatic Neoplasms Fluorouracil 16.5616929163 19003803 15113037 16500647
MESH:D010190 Pancreatic Neoplasms Quercetin 16.5616965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 16.5615976015
MESH:D010190 Pancreatic Neoplasms trichostatin A 16.5619294695
MESH:D010195 Pancreatitis Indomethacin 3.3115028970 17883296
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.0611578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 2.837296757
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.0216537180
MESH:D020734 Parkinsonian Disorders Indomethacin 3.5312349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.0211903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.5612520081
MESH:D010437 Peptic Ulcer Indomethacin 4.4711148446
MESH:D010438 Peptic Ulcer Hemorrhage Aspirin 4.8611156591
MESH:D010518 Periodontitis Indomethacin 4.2217225004
MESH:D010538 Peritonitis Ozone 3.4716369182
MESH:D020795 Photophobia Aspirin 5.0715240983
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 3.786228378
MESH:D011014 Pneumonia Ozone 3.7218929643 18381685 18007984
MESH:D011041 Poisoning Mustard Gas 3.1815727166
MESH:D017499 Porokeratosis alitretinoin 5.3116144296
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.9118163543
MESH:D011230 Precancerous Conditions Cyclosporine 11.9712371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 11.972563599
MESH:D011230 Precancerous Conditions Quercetin 11.9719056647
MESH:D047928 Premature Birth Indomethacin 4.4617000239
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 12.4910548101
MESH:D011297 Prenatal Exposure Delayed Effects Isotretinoin 12.4918769834
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 12.4911896295 11222880 11118676 11399792
MESH:D055728 Primary Myelofibrosis decitabine 10.2217616702
MESH:D055728 Primary Myelofibrosis trichostatin A 10.2217616702
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 8.5120887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 8.5120887781
MESH:D011471 Prostatic Neoplasms Apigenin 3.6617132221
MESH:D011471 Prostatic Neoplasms biochanin A 3.6612111696
MESH:D011471 Prostatic Neoplasms bisphenol A 3.6616740699
MESH:D011471 Prostatic Neoplasms Estradiol 3.6616740699
MESH:D011471 Prostatic Neoplasms fisetin 3.6618922931
MESH:D011471 Prostatic Neoplasms Fluorouracil 3.6618626508 19082440
MESH:D011471 Prostatic Neoplasms Genistein 3.6616925846 15378649 15256057
MESH:D011471 Prostatic Neoplasms Quercetin 3.6614715546 17292933
MESH:D011471 Prostatic Neoplasms sodium arsenite 3.6616039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.6615067354
MESH:D011471 Prostatic Neoplasms trichostatin A 3.6619789329 18798265
MESH:D011507 Proteinuria Indomethacin 7.2611849393
MESH:D011507 Proteinuria Tretinoin 7.2616636307
MESH:D011537 Pruritus Ethinyl Estradiol 7.2915861022 16919318
MESH:D011537 Pruritus Mustard Gas 7.2918058305
MESH:D011565 Psoriasis Cyclosporine 1.9516882103
MESH:D011596 Psychomotor Disorders Isotretinoin 5.2418769834
MESH:D011625 Pterygium Tretinoin 4.1116723453
MESH:D011629 Puberty, Precocious bisphenol A 4.1110548101
MESH:D029424 Pulmonary Disease, Chronic Obstructive Theophylline 4.6018983928
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.6317894541 10334151 17266442 17620002 17720292
MESH:D012004 Rectal Neoplasms Fluorouracil 3.4318286688 18722050 16160472 15538739
MESH:D015427 Reperfusion Injury pirinixic acid 2.0119058328
MESH:D012120 Respiration Disorders Chlorine 4.5218579056
MESH:D012135 Respiratory Sounds alachlor 4.2911874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.1918990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 2.853692021
MESH:D012208 Rhabdomyosarcoma decitabine 8.8519155313
MESH:D012208 Rhabdomyosarcoma Tretinoin 8.8516283617 16116481
MESH:D012220 Rhinitis Acetaldehyde 7.3917050345
MESH:D012220 Rhinitis Aspirin 7.3912372130
MESH:D012554 Schistosomiasis japonica Quercetin 4.8516862918
MESH:D012640 Seizures topiramate 3.6716499746
MESH:D012851 Sinus Thrombosis, Intracranial Aspirin 4.6012269725
MESH:D012871 Skin Diseases Mustard Gas 2.5016961503 12880345 15451306
MESH:D012878 Skin Neoplasms sodium arsenite 7.2718572023 19524636
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 7.2716192470
MESH:D012878 Skin Neoplasms Tretinoin 7.2716467112
MESH:D012893 Sleep Disorders Caffeine 4.6419395429
MESH:D007319 Sleep Initiation and Maintenance Disorders Caffeine 4.4217225163
MESH:D013088 Spermatocele Ethinyl Estradiol 9.2616709447
MESH:D013088 Spermatocele Tamoxifen 9.2616709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.3619457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.2612854658
MESH:D013272 Stomach Diseases Indomethacin 3.7416280098 17160473 17638125 15038085 15472012 18209964 16113693 10215738 16184426 10486359 17207306 10192188 18545984
MESH:D013274 Stomach Neoplasms Benzene 8.7412562636
MESH:D013274 Stomach Neoplasms decitabine 8.7419037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 8.7418456281
MESH:D013274 Stomach Neoplasms Fluorouracil 8.7417172411 16424979 18567086 19084572 18396642 15786421 19015929 17498489 16951190 17522103
MESH:D013274 Stomach Neoplasms Indomethacin 8.7415609394
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 8.7412958204 17575124
MESH:D013274 Stomach Neoplasms Tretinoin 8.7417261132
MESH:D013276 Stomach Ulcer Indomethacin 3.0011523592 17627676 16169175 16150113 18237397 16755016 16934674 12498302 18193104 16252198 11906479 12077510 18726076 18543354 17654042 18087811 12787963 15138204 18181030 17918041 15255614 12500499 18209962 10423059 1323529 12467913 17657623 10878458 11595431 11595415 17977527 11145282 16631530 15104355 18299717 11729361 17135157 14567935 10750652 16397915 18431645 17895592
MESH:D020521 Stroke Aspirin 3.8316403987
MESH:D019966 Substance-Related Disorders bisphenol A 3.3116684133 16045194
MESH:D019851 Thrombophilia Ethinyl Estradiol 2.9911994571
MESH:D013927 Thrombosis Aspirin 7.2717672075
MESH:D013927 Thrombosis Ethinyl Estradiol 7.2715669648
MESH:D013953 Thymus Neoplasms Benzene 4.2810850423
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.2112697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 25.661399818 6587162 3712494 7505956 6582329
MESH:D013964 Thyroid Neoplasms alachlor 25.668812207
MESH:D013964 Thyroid Neoplasms Butyrates 25.6617967635
MESH:D013964 Thyroid Neoplasms decitabine 25.6617967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 25.667505956
MESH:D013964 Thyroid Neoplasms Indomethacin 25.6614736730 11352223 18791128
MESH:D013964 Thyroid Neoplasms Tretinoin 25.6616026305 17045167
MESH:D013978 Tibial Fractures Estradiol 3.9919048282
MESH:D014062 Tongue Neoplasms Fluorouracil 7.8516280240
MESH:D014062 Tongue Neoplasms Tretinoin 7.8516051514
MESH:D014376 Tuberculosis Tretinoin 2.7716040207
MESH:D014456 Ulcer Indomethacin 4.2217380554 10574470
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 12.368074119
MESH:D001749 Urinary Bladder Neoplasms decitabine 12.3617616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Quercetin 12.3616720314
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 12.3611723127 16452187 17306315 16712894
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 12.3617572228 8653321 16712894
MESH:D014581 Urticaria Acetaminophen 6.8310982225
MESH:D014581 Urticaria Aspirin 6.8310982225 20485159
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 12.4216803524
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 12.4211813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 12.4216129372
MESH:D014591 Uterine Diseases bisphenol A 4.3214652134
MESH:D014594 Uterine Neoplasms Benzene 7.4312562636
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 7.4314692618
MESH:D014604 Uveal Neoplasms decitabine 10.5317785578
MESH:D014604 Uveal Neoplasms Tretinoin 10.5316752155
MESH:D014605 Uveitis Cyclosporine 3.291336536
MESH:D014652 Vascular Diseases sodium arsenite 3.7517056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.9012125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.9315869587 14671159
MESH:D014820 Vitiligo Tretinoin 3.4116761959
MESH:D014839 Vomiting Indomethacin 4.0611897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.5615886252
MESH:D015430 Weight Gain Dietary Fats 3.1616723640
MESH:D009396 Wilms Tumor Tretinoin 3.3816287080
MESH:D014985 Xerophthalmia Cyclosporine 3.7517120751
Pathway ID Pathway Name
REACT:20633 Bile salt and organic anion SLC transporters
REACT:604 Hemostasis
REACT:1046 Pyruvate metabolism and Citric Acid (TCA) cycle
REACT:15518 Transmembrane transport of small molecules
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA35813
    • Releated gene ID Related gene Name
    PA35813SLC16A1
    No data
    No data
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00119 - Pyruvic acid Dietary supplement;Micronutrient
    No data
    Drugbank ID Action Drug Name Description
    DB00119 inhibitor Pyruvic acid Dietary supplement;Micronutrient
    DB00142 substrate L-Glutamic Acid Dietary supplement;Micronutrient;Non-Essential Amino Acids
    DB00313 substrate Valproic Acid Anticonvulsants;Enzyme Inhibitors;Antimanic Agents;GABA Agents
    DB00345 substrate Aminohippurate Diagnostic aids;Indicators and Reagents
    DB00529 substrate Foscarnet Antiviral Agents;Reverse Transcriptase Inhibitors
    DB00563 substrate Methotrexate Antineoplastic Agents;Antirheumatic Agents;Antimetabolites;Enzyme Inhibitors;Folic Acid Antagonists;Dermatologic Agents;Immunosuppressive Agents;Nucleic Acid Synthesis Inhibitors;Abortifacient Agents, Nonsteroidal;Abortifacient Agents;Antimetabolites, Antineoplastic
    DB00627 substrate Vitamin C with Niacin and Niacinamide-Liq Vitamins (Vitamin B Complex);Vasodilator Agents;Antilipemic Agents;Vitamin B Complex
    DB00731 substrate Nateglinide Hypoglycemic Agents;Meglitinides
    DB00936 substrate Mobilat Anti-Infective Agents;Keratolytic Agents;Antifungal Agents
    DB01032 inhibitor Probenecid Uricosuric Agents;Adjuvants, Pharmaceutic
    DB01440 inhibitor Gamma Hydroxybutyric Acid Adjuvants, Anesthesia;Anesthetics, Intravenous
    DB01762 inhibitor Acetoacetic Acid
    DB03066 inhibitor D-Lactic Acid
    DB03166 substrate Acetic acid Antibacterial Agents;Indicators and Reagents
    DB04074 inhibitor Alpha-ketoisovalerate
    DB04216 inhibitor Quercetin Antioxidants
    DB04319 inhibitor 6-Deoxyglucose
    DB04348 substrate Taurocholic Acid Cholagogues and Choleretics;Detergents
    DB04398 inhibitor Lactic Acid
    DB04552 inhibitor Niflumic Acid Cyclooxygenase Inhibitors
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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