AutismKB 2.0

Annotation Detail for SLC20A1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SLC20A1 ( DKFZp686J2397,FLJ41426,GLVR1,Glvr-1,PIT1,PiT-1 )
Gene Full Name: solute carrier family 20 (phosphate transporter), member 1
Band: 2q14.1
Quick LinksEntrez ID:6574; OMIM: 137570; Uniprot ID:S20A1_HUMAN; ENSEMBL ID: ENSG00000144136; HGNC ID: 10946
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
Transmembrane transport of small molecules
No data
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Related Diseases/Disorders Top
No data
Desease IDDesease Name
2025Polyarthritis
No data
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of SLC20A1 mRNAincreases expression 19933214
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of SLC20A1 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of SLC20A1 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of SLC20A1 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of SLC20A1 mRNAaffects expression 16483693
D019324 beta-Naphthoflavone beta-Naphthoflavone results in increased expression of SLC20A1 mRNAincreases expression 19737606
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SLC20A1 mRNAaffects cotreatment|increases expression 18164116
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of SLC20A1 mRNAdecreases expression 20064835
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of SLC20A1 mRNAincreases expression 18061397
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of SLC20A1 mRNAincreases expression 20713471
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of SLC20A1 mRNAaffects expression 20382639
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of SLC20A1 mRNAdecreases expression 19150397
20018196
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of SLC20A1 mRNAdecreases expression 15003993
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of SLC20A1 proteinincreases expression 17544377
D002392 Catechin Catechin results in increased expression of SLC20A1 mRNAincreases expression 15465739
D002995 Clofibric Acid Clofibric Acid affects the expression of SLC20A1 mRNAaffects expression 17602206
D003474 Curcumin Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SLC20A1 mRNA]decreases expression|decreases reaction 18200517
D002945 Cisplatin SLC20A1 protein affects the susceptibility to Cisplatinaffects response to substance 16217747
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SLC20A1 mRNAaffects cotreatment|increases expression 18164116
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of SLC20A1 mRNAincreases expression 19638242
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of SLC20A1 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol promotes the reaction [IL1B protein results in increased expression of SLC20A1 mRNA]increases expression|increases reaction 12072388
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of SLC20A1 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SLC20A1 mRNAaffects cotreatment|increases expression 17942748
D005419 Flavonoids Flavonoids results in increased expression of SLC20A1 mRNAincreases expression 15465739
D017245 Foscarnet Foscarnet results in decreased activity of SLC20A1 proteindecreases activity 15641067
D017245 Foscarnet Foscarnet results in increased expression of SLC20A1 mRNAincreases expression 17438129
C056933 fumonisin B1 fumonisin B1 results in increased expression of SLC20A1 mRNAincreases expression 16221962
C075954 indolo(3,2-b)carbazole indolo(3,2-b)carbazole results in increased expression of SLC20A1 mRNAincreases expression 18061397
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of SLC20A1 mRNAincreases expression 20423518
D008070 Lipopolysaccharides phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of SLC20A1 mRNA]decreases reaction|increases expression 20423518
D009151 Mustard Gas Mustard Gas affects the expression of SLC20A1 mRNAaffects expression 15651846
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in increased expression of SLC20A1 mRNAincreases expression 17616710
D010126 Ozone Ozone results in increased expression of SLC20A1 mRNAincreases expression 16716893
C058305 phenethyl isothiocyanate phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of SLC20A1 mRNA]decreases reaction|increases expression 20423518
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of SLC20A1 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of SLC20A1 mRNAincreases expression 19482888
19270015
D010710 Phosphates IL8 protein promotes the reaction [SLC20A1 protein results in increased uptake of Phosphates]increases reaction|increases uptake 15641067
D010710 Phosphates IL8RA protein promotes the reaction [IL8 protein promotes the reaction [SLC20A1 protein results in increased uptake of Phosphates]]increases reaction|increases uptake 15641067
D010710 Phosphates SLC20A1 protein results in increased uptake of Phosphatesincreases uptake 15641067
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of SLC20A1 mRNAaffects binding|increases activity|increases expression 19710929
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of SLC20A1 mRNAaffects binding|decreases expression|increases activity 19710929
C006253 pirinixic acid pirinixic acid results in increased expression of SLC20A1 mRNAincreases expression 18445702
D010936 Plant Extracts Plant Extracts results in increased expression of SLC20A1 mRNAincreases expression 18061397
15465739
C025299 polyphenols polyphenols results in increased expression of SLC20A1 mRNAincreases expression 15465739
D011188 Potassium Potassium affects the expression of SLC20A1 proteinaffects expression 11473652
D011374 Progesterone Progesterone affects the expression of SLC20A1 mRNAaffects expression 17251523
C064116 S-(1,1,2,2-tetrafluoroethyl)cysteine S-(1,1,2,2-tetrafluoroethyl)cysteine results in increased expression of SLC20A1 mRNAincreases expression 16678137
C009250 sevoflurane sevoflurane affects the expression of SLC20A1 mRNAaffects expression 15967596
D013629 Tamoxifen Tamoxifen affects the expression of SLC20A1 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of SLC20A1 mRNAincreases expression 18061397
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SLC20A1 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of SLC20A1 mRNAincreases expression 18691609
17942748
16960034
19933214
16611356
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of SLC20A1 mRNAincreases expression 18796159
16960034
D014050 Toluene Toluene affects the expression of SLC20A1 mRNAaffects expression 18653662
D014212 Tretinoin Tretinoin results in decreased expression of SLC20A1 mRNAdecreases expression 16604517
D014302 Trinitrobenzenesulfonic Acid Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SLC20A1 mRNA]decreases expression|decreases reaction 18200517
D014302 Trinitrobenzenesulfonic Acid Trinitrobenzenesulfonic Acid results in decreased expression of SLC20A1 mRNAdecreases expression 17982090
18200517
D015032 Zinc Zinc results in decreased expression of SLC20A1 mRNAdecreases expression 17074742
D019287 Zinc Sulfate Zinc Sulfate results in decreased expression of SLC20A1 mRNAdecreases expression 17074742
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.1114745880
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 6.876195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 6.8714514962 15322242 11752688
MESH:D000138 Acidosis Ammonium Chloride 9.1918287403
MESH:D000138 Acidosis Zinc Sulfate 9.197265320
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.5017505938
MESH:D000169 Acrodermatitis Zinc 4.9716889938 17202136 17190629
MESH:D058186 Acute Kidney Injury Cisplatin 3.5817670903 12690470 15814532
MESH:D055371 Acute Lung Injury Lipopolysaccharides 7.7311850527 18653653
MESH:D055371 Acute Lung Injury pirinixic acid 7.7318653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 6.3520464547 20127859
MESH:D000230 Adenocarcinoma Cisplatin 6.3517638652 11798837
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 6.3514692618
MESH:D000236 Adenoma Benzo(a)pyrene 9.706695378
MESH:D000236 Adenoma beta-Naphthoflavone 9.7019389873
MESH:D000236 Adenoma Diethylnitrosamine 9.706695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 21.3119061943 18056438 16434500 17620307 17162532 19052882
MESH:D018248 Adenoma, Liver Cell Phenobarbital 21.3117620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 21.3116434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 21.3116835633
MESH:D017088 AIDS-Related Opportunistic Infections Foscarnet 6.2911363124
MESH:D019973 Alcohol-Related Disorders Curcumin 4.6417887948
MESH:D000505 Alopecia Tretinoin 3.2715955085
MESH:D000544 Alzheimer Disease Curcumin 8.5515590663
MESH:D000544 Alzheimer Disease Ozone 8.5515513908
MESH:D000544 Alzheimer Disease Plant Extracts 8.5516962711
MESH:D000544 Alzheimer Disease Zinc 8.5516325427 17119284 16580781 16410023
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.5811748828
MESH:D000755 Anemia, Sickle Cell Zinc 4.4916916123
MESH:D000799 Angioedema Acetaminophen 3.4010982225
MESH:D000860 Anoxia Zinc Sulfate 4.597265320
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.6519183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.0511256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 10.7515885639
MESH:D001169 Arthritis, Experimental Plant Extracts 10.7514686799
MESH:D001169 Arthritis, Experimental Tretinoin 10.7516412693
MESH:D001172 Arthritis, Rheumatoid Curcumin 6.7616807698
MESH:D001172 Arthritis, Rheumatoid Ozone 6.7615570426
MESH:D001172 Arthritis, Rheumatoid Tretinoin 6.7616292516
MESH:D001249 Asthma Mustard Gas 10.0910378619
MESH:D001249 Asthma Ozone 10.0916373670 17854713
MESH:D001249 Asthma Tretinoin 10.0916456186
MESH:D001249 Asthma Zinc 10.0917085522
MESH:D050197 Atherosclerosis Curcumin 3.0618704882
MESH:D001321 Autistic Disorder Acetaminophen 1.4718445737
MESH:D001327 Autoimmune Diseases Curcumin 4.0719761891
MESH:D001471 Barrett Esophagus Tretinoin 3.9916935849
MESH:D001768 Blister Mustard Gas 4.7319167455
MESH:D001778 Blood Coagulation Disorders pirinixic acid 13.0419483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 13.0412125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 13.0416206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.3515340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.4815746008
MESH:D019046 Bone Marrow Neoplasms Cisplatin 4.4514601052
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.9017868700
MESH:D001930 Brain Injuries Progesterone 9.6515665606 15380490 15845082
MESH:D001930 Brain Injuries Zinc 9.6517109824
MESH:D002545 Brain Ischemia Curcumin 9.0616770732
MESH:D002545 Brain Ischemia Plant Extracts 9.0616041641
MESH:D001932 Brain Neoplasms Curcumin 3.5717596214
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 4.3120146248 17474063
MESH:D001943 Breast Neoplasms Cisplatin 4.3119526202 18382427
MESH:D001943 Breast Neoplasms Curcumin 4.3116243823 18593918 18462866 19250217
MESH:D001943 Breast Neoplasms Diethylnitrosamine 4.3117474063
MESH:D001943 Breast Neoplasms Progesterone 4.3115562024 16175315 17614352
MESH:D001943 Breast Neoplasms Tamoxifen 4.3120065188 17893378 18855134 18815881 19142967 20544844 16273361 15565566 18984771 19200415 21138602 15668708 16202921 20859285 17261762 19189210 17242785 19084267 20005174 19221464 20135344 19011961 19059307 21152245 19103187 17440819 16873071 19189212 19066611 19115204 18351453 19155303 19288272 18629630 20390343 17049068 19487384 16818667 19244106 11161223 18821012 18997820 19410462 19289846 18425577
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 4.3120435547
MESH:D001943 Breast Neoplasms Tretinoin 4.3116873071 16443354 16166294
MESH:D016535 Bronchial Hyperreactivity Ozone 3.3414754758 18315731 16777450 15516495 18417511 17626835 19059883
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.7315286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.5417687719 10378619
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.1616813970
MESH:D002057 Burns, Chemical Plant Extracts 4.909625245
MESH:D002100 Cachexia Ozone 4.3116183385
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.3616124888 15700767 18705752 16192424 10355542 16227642 16011737 15721981 16050911 15673190 16097048 3786805
MESH:D002277 Carcinoma Curcumin 7.1618593918
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.1616835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.0819066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.7216168501
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 21.1216705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 21.1216705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 21.123084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 21.1218788625
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 21.1217982673
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 21.1219539802 19822196 17978847 21159647 19519916 16540662 18210153 16830150 16328049 17162532 19919837 11831363 18506893 10737359 20727157 17055752 17761372 18691550 16502159 10672840 19701751 20512989 18788625 19208518 20935162 20214788 20084675 18665156 20007298 19107877 3581430 16681979 18785209 16935385 18393292 18978308 19335982 18971187 16878318 19383236 19052882 18056438 17428255 19418558 19394651 16779866 20514400 20432363 20524982 16569478 16288022 20101231 17173139 18494052 16807293 16698587 19171122 3084413 17138121
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 21.121701930 20007298 20935162 17173139 6705139
MESH:D006528 Carcinoma, Hepatocellular Plant Extracts 21.1218834353
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 21.1216924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 21.121917145
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 5.2312023789 16685392
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 5.2318414057
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 12.8220419170
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 12.826189445 17066447 18337622
MESH:D002294 Carcinoma, Squamous Cell Curcumin 12.8218462866
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 12.8216051514 16096774
MESH:D002294 Carcinoma, Squamous Cell Zinc 12.8216543248
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.2417572228
MESH:D006332 Cardiomegaly Plant Extracts 6.1517645561
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.1518850075 18670907 16120746
MESH:D002318 Cardiovascular Diseases Zinc 3.3616936243
MESH:D002386 Cataract Acetaminophen 6.3610977129
MESH:D002386 Cataract Tretinoin 6.3617460283
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 9.446135515
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 9.4420889678
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 9.442727394 17174075 21159647 7505956
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.834080065
MESH:D002547 Cerebral Palsy Toluene 5.429294310
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.1616129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.1219052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.1216835633
MESH:D002779 Cholestasis Ethinyl Estradiol 6.6817681005 15861022 16919318 17110522 16105132 17333356 11677210
MESH:D002779 Cholestasis pirinixic acid 6.6819176532
MESH:D002822 Choriocarcinoma Tretinoin 4.7216461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.1212621046 8697196 15340226 16354765 15668235
MESH:D002972 Cleft Palate Tretinoin 5.129407595
MESH:D003092 Colitis Curcumin 13.7218200517 16782535 16804969
MESH:D003092 Colitis Tretinoin 13.7217035595
MESH:D003092 Colitis Trinitrobenzenesulfonic Acid 13.7216474422 18023891 18200517 16782535 17991707 16804969 17936198 16867261 11698051
MESH:D003093 Colitis, Ulcerative phenethyl isothiocyanate 5.9020423518
MESH:D003093 Colitis, Ulcerative Trinitrobenzenesulfonic Acid 5.9017276891
MESH:D003103 Coloboma Curcumin 4.1618809619
MESH:D003110 Colonic Neoplasms Curcumin 3.7819359593 16340194
MESH:D003110 Colonic Neoplasms polyphenols 3.7816293270
MESH:D015179 Colorectal Neoplasms Cisplatin 2.3215273666
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.7014669216 17141729
MESH:D016510 Corneal Neovascularization Curcumin 4.4718497527
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 5.0010048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Toluene 5.009294310
MESH:D019465 Craniofacial Abnormalities Tretinoin 5.009142499 9125849 9211117 8800419 16925845 17551590 9224671 10589399 14991402 9664655
MESH:D019465 Craniofacial Abnormalities Zinc 5.0019302082
MESH:D003490 Cyanosis 2,4-dinitrotoluene 9.4918551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 9.4918551238
MESH:D003586 Cytomegalovirus Infections Foscarnet 6.4311050094 8781616
MESH:D017726 Cytomegalovirus Retinitis Foscarnet 6.4411363124
MESH:D003643 Death Toluene 5.236431079
MESH:D003711 Demyelinating Diseases Tamoxifen 3.9419031437
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2218249437
MESH:D003920 Diabetes Mellitus Zinc 3.8416479319
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 6.4118403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 6.4120387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.4117107852
MESH:D003928 Diabetic Nephropathies Curcumin 13.0718204486
MESH:D003928 Diabetic Nephropathies Plant Extracts 13.0719706694
MESH:D003928 Diabetic Nephropathies Tamoxifen 13.0719279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.0717187935
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 19.6518551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 19.6521346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 19.6519164858 11834606 15968718 10663392 14550746 14725611 16081117 16227642 15619225 17906064 19923254 18071297 16393943 16781746 11739529 19416960 11743745 18713872 10774834 19739265 16177239 14986274 19370779 11461765 19085960 12153990 19420014 10915739 11529661 12958197 16109766 11287661 12540782 12705907 11421492 12392966 17522070 17562736 12594235 2444490 16485898
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 19.6515968718 3786805 17522070 3732212 16227642 10092053 21278145 6884620 11566570 2869522 15998439 7120509 4309450 15027814 9327722 7179309 10915739 19336974 16177239 7440962 6623471 19085960
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 19.6519107877
MESH:D056486 Drug-Induced Liver Injury fumonisin B1 19.6516221962
MESH:D056486 Drug-Induced Liver Injury polyphenols 19.6519370779
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 19.6520420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.6619426721
MESH:D004362 Drug Toxicity Cisplatin 7.1115033597 19839026 12649298 12231392
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 7.1111462148
MESH:D004381 Duodenal Ulcer Curcumin 3.6417351913
MESH:D004421 Dystonia Phenobarbital 3.611851702
MESH:D004487 Edema Mustard Gas 13.3411428631 11428647 9260866 11402378
MESH:D004487 Edema pirinixic acid 13.3412083418
MESH:D004487 Edema Plant Extracts 13.3412787963
MESH:D004487 Edema Tetrachlorodibenzodioxin 13.3412711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.4816714409 15322242 18230668
MESH:D004489 Edema, Cardiac Tretinoin 10.4818230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 12.9612538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 12.9617692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 12.9619031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 6.4820544844 16202921 19155303 17893378
MESH:D016889 Endometrial Neoplasms Tretinoin 6.4816569247
MESH:D004715 Endometriosis Progesterone 7.6916134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 7.6910568697 9294722
MESH:D004719 Endomyocardial Fibrosis Plant Extracts 5.2415268973
MESH:D019446 Endotoxemia Lipopolysaccharides 3.9717637181 15328337 15821434
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.693659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.433922381 11558140
MESH:D004827 Epilepsy Phenobarbital 6.1820417680
MESH:D004827 Epilepsy Plant Extracts 6.1819700373 19439326
MESH:D004832 Epilepsy, Absence Phenobarbital 3.186401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.837750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.593659116
MESH:D004890 Erythema Mustard Gas 4.739357497
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.6816302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 12.4620426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 12.4616530937
MESH:D004938 Esophageal Neoplasms Cisplatin 12.4615464296 16481741 17638652 16785472 15173087
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 12.4615547721 15547733 15264214 16805852 16704527 16510608 15623463 15878914 15150132
MESH:D004938 Esophageal Neoplasms Zinc 12.4616543248
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.7611564622
MESH:D005124 Eye Abnormalities Tretinoin 7.7616938888 9664655
MESH:D005234 Fatty Liver Carbon Tetrachloride 31.0719224547 12795759 16239168 15959796 17595544 12631006 61145 16045604
MESH:D005234 Fatty Liver Curcumin 31.0719297423
MESH:D005234 Fatty Liver Diethylnitrosamine 31.0720387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 31.0715345470
MESH:D005234 Fatty Liver pirinixic acid 31.0719236843 20131406
MESH:D005234 Fatty Liver Plant Extracts 31.0715975614
MESH:D005234 Fatty Liver Tamoxifen 31.0714986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 2.9716709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.0411858732
MESH:D005334 Fever Lipopolysaccharides 3.6411852909 9205823
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.1014745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.7519069698
MESH:D005355 Fibrosis Carbon Tetrachloride 23.2918705752
MESH:D005355 Fibrosis Curcumin 23.2918705752
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 23.2920067830
MESH:D005355 Fibrosis Tretinoin 23.2917994277
MESH:D005355 Fibrosis Trinitrobenzenesulfonic Acid 23.2917994277
MESH:D005756 Gastritis Acetaminophen 9.7016983495
MESH:D005756 Gastritis Zinc 9.7017241300
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.2718462866
MESH:D005909 Glioblastoma Curcumin 6.3417596214
MESH:D005909 Glioblastoma Tretinoin 6.3417312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.1510696789
MESH:D006130 Growth Disorders Zinc 3.6817217573
MESH:D006258 Head and Neck Neoplasms Cisplatin 11.3315102660 15464296
MESH:D006258 Head and Neck Neoplasms Curcumin 11.3318462866 18829502
MESH:D006258 Head and Neck Neoplasms Tretinoin 11.3316096774
MESH:D034381 Hearing Loss Cisplatin 3.9319898482
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.7216084493
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 4.0715464296
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 9.7120471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 9.7111294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 9.7114991402 9664655
MESH:D006333 Heart Failure pirinixic acid 10.3720558911
MESH:D006333 Heart Failure Plant Extracts 10.3718097624
MESH:D006333 Heart Failure Zinc 10.3717162251
MESH:D006335 Heart Injuries Zinc 5.3317074742
MESH:D016481 Helicobacter Infections Zinc 4.1417241300
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.0116366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.9511000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.1919900420 19110552
MESH:D006527 Hepatolenticular Degeneration Zinc 9.9217276780
MESH:D006527 Hepatolenticular Degeneration Zinc Sulfate 9.9217063115
MESH:D006529 Hepatomegaly fumonisin B1 17.2516221962
MESH:D006529 Hepatomegaly Phenobarbital 17.2516109766
MESH:D006529 Hepatomegaly pirinixic acid 17.2519772884 16221962 18467677 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 17.2516120746 12621046 15340226
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.6217701891
MESH:D006561 Herpes Simplex Plant Extracts 4.2010715843
MESH:D015658 HIV Infections Foscarnet 6.8311050094 11362904
MESH:D015658 HIV Infections Plant Extracts 6.8312878215
MESH:D006689 Hodgkin Disease Cisplatin 3.2416200630 16170182
MESH:D019584 Hot Flashes Plant Extracts 4.3114716179 16566672 17454163
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.618697196 15340226 18606429 16354765 16959395
MESH:D006930 Hyperalgesia Acetaminophen 6.5016870215
MESH:D006930 Hyperalgesia Tretinoin 6.5016870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.1016899240
MESH:D006937 Hypercholesterolemia Curcumin 3.6718704882
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.1516778211
MESH:D006943 Hyperglycemia pirinixic acid 2.8120558911
MESH:D020138 Hyperhomocysteinemia Catechin 8.7217292331
MESH:D020138 Hyperhomocysteinemia Plant Extracts 8.7216484555
MESH:D006949 Hyperlipidemias Plant Extracts 4.0815268973 15975614
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.7418670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.6715338365
MESH:D020514 Hypokalemic Periodic Paralysis Potassium 5.4319822448
MESH:D007015 Hypophosphatemia, Familial Foscarnet 6.998948520
MESH:D007021 Hypospadias Ethinyl Estradiol 3.3916569931 16945680
MESH:D007022 Hypotension Zinc Sulfate 4.087265320
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 3.9815869954
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.0712013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.2017937319
MESH:D007249 Inflammation Curcumin 32.6917151092 18403477 16956363
MESH:D007249 Inflammation Diethylnitrosamine 32.6918785209
MESH:D007249 Inflammation Flavonoids 32.6917296493
MESH:D007249 Inflammation Lipopolysaccharides 32.699205823 17255318 12878042 17237260 17963957
MESH:D007249 Inflammation Mustard Gas 32.6911428647 9260866 9357497 11402378 17524151 11428620 16001271 8975870 11428631
MESH:D007249 Inflammation Plant Extracts 32.6916366677 15997105 12787963 19332304
MESH:D007249 Inflammation polyphenols 32.6916366677
MESH:D007249 Inflammation Progesterone 32.6915869954
MESH:D007249 Inflammation Tamoxifen 32.6919457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 32.6912200463 12878042
MESH:D015212 Inflammatory Bowel Diseases Curcumin 6.0718200517 18596194
MESH:D015212 Inflammatory Bowel Diseases Trinitrobenzenesulfonic Acid 6.0718200517
MESH:D007333 Insulin Resistance pirinixic acid 2.3516306350
MESH:D007410 Intestinal Diseases Tretinoin 8.5917994277
MESH:D007410 Intestinal Diseases Trinitrobenzenesulfonic Acid 8.5917994277
MESH:D007414 Intestinal Neoplasms Curcumin 8.8710783313
MESH:D007414 Intestinal Neoplasms Plant Extracts 8.8712628509 12584176 12351151
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.2317255318
MESH:D007511 Ischemia Zinc 4.2116584753
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.6516580747
MESH:D007569 Jaw Abnormalities Tretinoin 8.6517551590 15992940
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.7015464296
MESH:D007674 Kidney Diseases Acetaminophen 8.7012587719 15629191
MESH:D007674 Kidney Diseases Cisplatin 8.7012649298 12231392 15190930 19839026 18289764
MESH:D007674 Kidney Diseases Zinc 8.7016960431
MESH:D007676 Kidney Failure, Chronic Zinc 4.0416518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 10.3916705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 10.3916705839
MESH:D007680 Kidney Neoplasms Tamoxifen 10.3918625569
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 4.3611231351
MESH:D007859 Learning Disorders sevoflurane 4.3519212262
MESH:D007889 Leiomyoma Curcumin 4.1718555241
MESH:D016773 Leishmaniasis, Cutaneous Zinc Sulfate 3.9215237267
MESH:D007938 Leukemia Curcumin 5.7418462866
MESH:D007938 Leukemia Tretinoin 5.7417143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 3.8216106398
MESH:D007951 Leukemia, Myeloid Tretinoin 3.3219285840 16482212 16932348
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0019850784 16294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 2.879834237 16891316 19035177 17294898 17217047 16788101 17107899 17361223 17368321 19075265 17712046 17649720 16140955 17301526 12679006 16935935 15748426 16823087 19029980 16331271 19225113 19642359 16766008 17506722 17339181
MESH:D015458 Leukemia, T-Cell Curcumin 4.3516106398
MESH:D007970 Leukopenia Lipopolysaccharides 4.2715821434
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.009224671
MESH:D008064 Lipidoses Tamoxifen 2.8517567588 15342952
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 13.7616239168 11903743 11408273 17334410 21278145 17157831 16943688 17174718 16221502
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 13.7620032147 18407596 18522880 18665156 19638242
MESH:D008103 Liver Cirrhosis Phenobarbital 13.7621047994
MESH:D008103 Liver Cirrhosis Plant Extracts 13.7617157831
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 12.0814716833 14716496 15959796 15338365 17525996 16136751 12667390 18412020 12958196 17565644 18420326 20821823 12741479 18210741 12632514 17922224 18263696 17823541 18187930 14512876 18395095 14620537 17805973 16638106 18418968 15931870 17761835 17714472 18279442 18166357 17708605 15057751 18205269 11481614 17766677 12445418 18339082 18054572 15673190 16015684 17640975 15650968 12609069 15925388 15996030 17944888 15730626 12546737 16011737 12389079 15123356 15052691 17631135 18251166 12445421 15893842 12632512 18395914 13678700 18277467 18429990 18481824 12586293 18376398 18156304 18472094 16192424 17557913 15876570 17698563 16027843 12649538 17721639 18317297 15362042 18705752 17976157 16116963 10355542 15370692 12898905 18006644 16033810 17869086 18472332 14724832 17481882 16248980 16097048 12666154 15818738 14748882 17900296
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 12.0818006644 18705752 17355460
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 12.0812878042
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 12.0815474484
MESH:D008106 Liver Cirrhosis, Experimental Plant Extracts 12.0815479170
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 12.0818564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 12.0812878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 12.0818397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 17.4019014921 11587558 12969438 16611625 19784758 12587719 16610002 19460945
MESH:D008107 Liver Diseases Carbon Tetrachloride 17.4017285989 16964402 15720792 15830285 16246199
MESH:D008107 Liver Diseases Curcumin 17.4016956363
MESH:D008107 Liver Diseases Diethylnitrosamine 17.4017034775
MESH:D008107 Liver Diseases Phenobarbital 17.4019363144
MESH:D008107 Liver Diseases Plant Extracts 17.4017034775
MESH:D008107 Liver Diseases polyphenols 17.4016698588
MESH:D017093 Liver Failure Carbon Tetrachloride 3.7415123358
MESH:D017114 Liver Failure, Acute Acetaminophen 8.1716871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 8.1714706259 16899240
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 34.547678174
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 34.5420195826 21137059
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 34.5419389873 21295105
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 34.5419294768
MESH:D008113 Liver Neoplasms Clofibric Acid 34.5417602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 34.5421167192 12112319 20583210 19294768 18977376 19256749 20118626 20452335 20101389 21278145 19850985 9163691 18978307 19426721 19551842 19499222 15885732 20405173 19073162 18754104 19255062 10737359 19090486 19833225 15175105 16942905 20501860 20492335 2422723 12771043 19254457 20137499 2862719 19427195 18648771 19812893 19996281 19638242 20434301 18644402 19642983 19690152 21071580 21047994
MESH:D008113 Liver Neoplasms Phenobarbital 34.548742319 19073162 19482888 15975961 19812893 21047994
MESH:D008113 Liver Neoplasms pirinixic acid 34.5415890375 20007298 16377806
MESH:D008113 Liver Neoplasms Plant Extracts 34.5419168119
MESH:D008113 Liver Neoplasms Tamoxifen 34.5416684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 34.5416984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 19.792876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 19.7918164116
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 19.7912014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 19.792563599 18093689 19004024 18164116 21159647 18079962 17174075 19009564 9362446 16267830 16842330 18253720 18282651 17942915 17854601 19539802 19519916 18775883 18308698 19126423 18544905 3124819
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 19.791399818 18308698 6150874 17172636 2563599
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 19.7912151625
MESH:D008171 Lung Diseases Mustard Gas 6.6418161513 18702808
MESH:D008171 Lung Diseases Ozone 6.6419066396 8266340
MESH:D055370 Lung Injury Lipopolysaccharides 7.8521114838
MESH:D055370 Lung Injury Ozone 7.8520417186
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 14.1020869020 17053015 6695378 20464547 18569708 18520028 20064080 20135361 18816296
MESH:D008175 Lung Neoplasms Cisplatin 14.1017225452 6189445 11798837
MESH:D008175 Lung Neoplasms Curcumin 14.1019359593 18462866 16243823
MESH:D008175 Lung Neoplasms Diethylnitrosamine 14.1021163286 6695378 20970405 20512841
MESH:D008175 Lung Neoplasms Mustard Gas 14.103148597 8781369
MESH:D008175 Lung Neoplasms Ozone 14.108597069 7614698
MESH:D008175 Lung Neoplasms Plant Extracts 14.1020869020
MESH:D008175 Lung Neoplasms Tamoxifen 14.1018625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 14.1019555203 11884234
MESH:D008223 Lymphoma Curcumin 3.2818462866
MESH:D016399 Lymphoma, T-Cell Curcumin 4.2716173963
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.3319428831
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 8.4311408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 8.4311731420 16827153 14580682 19196722 19196723
MESH:D008325 Mammary Neoplasms, Experimental Zinc 8.4312773700
MESH:D020149 Manganese Poisoning Tamoxifen 4.1119453300
MESH:D008527 Medulloblastoma Tretinoin 2.6017453147
MESH:D008545 Melanoma Cisplatin 6.5712393984 18505091 16248763 16809738 12374674 18176117 11135225 15577323 12883367 16432458 17761969 17023156 18332650
MESH:D008545 Melanoma Curcumin 6.5717885582 18462866
MESH:D008545 Melanoma Tamoxifen 6.5712393984 19393235
MESH:D008545 Melanoma Tretinoin 6.5716752155
MESH:D018328 Melanoma, Amelanotic Cisplatin 10.0715990972
MESH:D018328 Melanoma, Amelanotic Tamoxifen 10.0715990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.1519513568
MESH:D008569 Memory Disorders Curcumin 8.6017263510
MESH:D008569 Memory Disorders sevoflurane 8.6019212262
MESH:D008591 Meningomyelocele Tretinoin 4.0016940565
MESH:D001523 Mental Disorders Phosphates 4.5912686366
MESH:D008607 Mental Retardation Toluene 3.499294310
MESH:D008654 Mesothelioma Cisplatin 3.0617638057
MESH:D008679 Metaplasia Ozone 4.6710496685
MESH:D019957 Motor Skills Disorders Toluene 4.849294310
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 2.8616381670
MESH:D009101 Multiple Myeloma Curcumin 3.2119372569
MESH:D009134 Muscular Atrophy, Spinal Curcumin 4.4917962980
MESH:D009135 Muscular Diseases pirinixic acid 3.0916239165
MESH:D009190 Myelodysplastic Syndromes Tretinoin 2.8317596541
MESH:D009203 Myocardial Infarction pirinixic acid 1.9619151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.6812213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.6216411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.0417484760
MESH:D009336 Necrosis 2,4-dinitrotoluene 8.9118551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 8.9118551238 7678174
MESH:D009361 Neoplasm Invasiveness Curcumin 3.9618495463
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.113581430 9029167
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.1119393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.3619410462
MESH:D009369 Neoplasms Benzo(a)pyrene 10.0011141357
MESH:D009369 Neoplasms Cisplatin 10.0016773208
MESH:D009369 Neoplasms pirinixic acid 10.0017405874
MESH:D009369 Neoplasms Tretinoin 10.0016594593 16946489
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 9.3812497104
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 9.3819196722 19189210 19200415
MESH:D009395 Nephritis, Interstitial Cisplatin 4.0615464296
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 8.1514600291
MESH:D009421 Nervous System Malformations Tretinoin 8.159125849
MESH:D009423 Nervous System Neoplasms Curcumin 5.1918462866
MESH:D009436 Neural Tube Defects Tretinoin 2.779142499
MESH:D019954 Neurobehavioral Manifestations Plant Extracts 4.7617168769
MESH:D009447 Neuroblastoma Cisplatin 3.228761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.0218514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.0220387270
MESH:D017599 Neuroectodermal Tumors Cisplatin 4.278761367
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.6820387270
MESH:D009503 Neutropenia Mustard Gas 3.5816761898 7688884
MESH:D009765 Obesity Curcumin 6.8219297423
MESH:D009765 Obesity pirinixic acid 6.8220558911
MESH:D009765 Obesity Plant Extracts 6.8219056576 20132043
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 7.6516049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 7.6516049721
MESH:D010018 Osteomalacia Phenobarbital 3.9317016548
MESH:D010024 Osteoporosis Curcumin 3.2018719352
MESH:D010051 Ovarian Neoplasms Cisplatin 10.0819769630 15464296 6897625 17225452
MESH:D010051 Ovarian Neoplasms Curcumin 10.0818462866 19020741
MESH:D010051 Ovarian Neoplasms Progesterone 10.0816525653 17393432
MESH:D010051 Ovarian Neoplasms Tretinoin 10.0816936753
MESH:D010146 Pain Acetaminophen 5.4516870215
MESH:D010146 Pain Tretinoin 5.4516870215
MESH:D010190 Pancreatic Neoplasms Cisplatin 14.5019003803
MESH:D010190 Pancreatic Neoplasms Curcumin 14.5017440100 19401701 19196508
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 14.5016540662
MESH:D010190 Pancreatic Neoplasms Phenobarbital 14.5016965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 14.5015976015
MESH:D010195 Pancreatitis Trinitrobenzenesulfonic Acid 3.8117698068
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.2911578682
MESH:D010212 Papilloma Plant Extracts 4.0816517061 15173996
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.8112520081
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 3.9015464296
MESH:D010538 Peritonitis Ozone 3.7116369182
MESH:D010997 Pleural Neoplasms Cisplatin 4.9017638057
MESH:D011014 Pneumonia Lipopolysaccharides 9.6712224865 11605937
MESH:D011014 Pneumonia Ozone 9.6718007984 18381685 18929643
MESH:D011041 Poisoning Mustard Gas 3.4115727166
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.1518163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 7.892563599
MESH:D011230 Precancerous Conditions Phenobarbital 7.892563599
MESH:D011225 Pre-Eclampsia Zinc 3.8417114810
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 2.7611399792 11118676 11222880 11896295
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 1.9317292933
MESH:D011471 Prostatic Neoplasms Curcumin 1.9318226269 11398177 18156803 18769126 12497104 10851300 15129424
MESH:D011471 Prostatic Neoplasms Plant Extracts 1.9314666653 17804756
MESH:D011471 Prostatic Neoplasms Tamoxifen 1.9315067354
MESH:D011471 Prostatic Neoplasms Zinc 1.9316700911 12429649 16606632 16517595
MESH:D011507 Proteinuria Tretinoin 3.2116636307
MESH:D011537 Pruritus Ethinyl Estradiol 8.1015861022 16919318
MESH:D011537 Pruritus Mustard Gas 8.1018058305
MESH:D019310 Pseudolymphoma Phenobarbital 4.0612752131
MESH:D011625 Pterygium Tretinoin 4.3616723453
MESH:D011656 Pulmonary Emphysema Curcumin 4.1519168576
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.7517620002 17266442 17720292 17894541 10334151
MESH:D051437 Renal Insufficiency Cisplatin 3.9915464296
MESH:D015427 Reperfusion Injury pirinixic acid 2.1719058328
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 3.6318379247 10666014
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.4410835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.4318990726
MESH:D012162 Retinal Degeneration Zinc 3.8016584753
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.7016283617 16116481
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.6918045962
MESH:D012509 Sarcoma Curcumin 3.7418462866
MESH:D012512 Sarcoma, Ewing's Cisplatin 4.0214601052
MESH:D012640 Seizures 2,4-dinitrotoluene 11.6818551238
MESH:D012640 Seizures 2,6-dinitrotoluene 11.6818551238
MESH:D012640 Seizures Phenobarbital 11.6811442880 4039156 3137016 16876388
MESH:D012640 Seizures Toluene 11.689294310 6431079
MESH:D003294 Seizures, Febrile Phenobarbital 4.396407741
MESH:D018805 Sepsis Curcumin 3.7218389075
MESH:D012871 Skin Diseases Mustard Gas 2.5916961503 15451306 12880345
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 15.6319755658 10029692
MESH:D012878 Skin Neoplasms Plant Extracts 15.6315173996 16517061
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 15.638532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 15.6316192470
MESH:D012878 Skin Neoplasms Tretinoin 15.6316467112
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.9015464296
MESH:D013088 Spermatocele Ethinyl Estradiol 10.1016709447
MESH:D013088 Spermatocele Tamoxifen 10.1016709447
MESH:D013119 Spinal Cord Injuries Progesterone 9.4415862959 16503802
MESH:D013119 Spinal Cord Injuries Tamoxifen 9.4419457130
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 5.832093021 20155912
MESH:D013274 Stomach Neoplasms Cisplatin 5.8318396642 17522103 15958060
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 5.8318456281
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 5.8312958204 17575124
MESH:D013274 Stomach Neoplasms Tretinoin 5.8317261132
MESH:D013276 Stomach Ulcer Curcumin 6.4319188055 16631530
MESH:D013276 Stomach Ulcer Plant Extracts 6.4318193104 12787963 17135157 15255614 18237397
MESH:D013705 Temporomandibular Joint Disorders Plant Extracts 11.8117997062
MESH:D013705 Temporomandibular Joint Disorders polyphenols 11.8117997062
MESH:D013733 Testicular Diseases phenethyl isothiocyanate 9.4715864552
MESH:D013733 Testicular Diseases Toluene 9.4710048760 10514026
MESH:D013736 Testicular Neoplasms Cisplatin 4.2317225452 15464296
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.7915821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.2211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.7915669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.4612697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 10.077505956
MESH:D013964 Thyroid Neoplasms Phenobarbital 10.071399818
MESH:D013964 Thyroid Neoplasms Tretinoin 10.0716026305 17045167
MESH:D014062 Tongue Neoplasms Tretinoin 8.7416051514
MESH:D014062 Tongue Neoplasms Zinc 8.7416543248
MESH:D014376 Tuberculosis Tretinoin 2.9516040207
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 17.4816049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 17.4816049721
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 17.4817053015
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 17.4815464296 12973940 17225452
MESH:D001749 Urinary Bladder Neoplasms Curcumin 17.4818593936
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 17.488653321 17572228 16712894
MESH:D014565 Urogenital Neoplasms Curcumin 4.8318462866
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 10.5510091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 10.5510091137
MESH:D014581 Urticaria Acetaminophen 2.5810982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 8.3316803524
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 8.3316129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.8914692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.1716752155
MESH:D014625 Vaginal Neoplasms Cisplatin 4.1915577323
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.1512125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.1514671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Plant Extracts 4.3318097624
MESH:D020257 Ventricular Remodeling Plant Extracts 4.8818097624
MESH:D014820 Vitiligo Tretinoin 3.6516761959
MESH:D014839 Vomiting Cisplatin 4.2811897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.8115886252
MESH:D009396 Wilms Tumor Tretinoin 3.6016287080
MESH:D014947 Wounds and Injuries Plant Extracts 3.9020213670 19894650
Pathway ID Pathway Name
REACT:15518 Transmembrane transport of small molecules
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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