AutismKB 2.0

Annotation Detail for TMEM108


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Basic Information Top
Gene Symbol:TMEM108 ( CT124,MGC3040 )
Gene Full Name: transmembrane protein 108
Band: 3q22.1
Quick LinksEntrez ID:66000; OMIM: NA; Uniprot ID:TM108_HUMAN; ENSEMBL ID: ENSG00000144868; HGNC ID: 28451
Relate to Another Database: SFARIGene; denovo-db
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of TMEM108 mRNAaffects expression 17562736
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 5.2610982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8610977129
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6916177239 18713872 11461765 11743745 18071297 14550746 12594235 12540782 19416960 10915739 16393943 10663392 19164858 11739529 10774834 17906064 11834606 15619225 16227642 12705907 12392966 11287661 19085960 12153990 2444490 11529661 15968718 19739265 14986274 17562736 16109766 16081117 19370779 14725611 19420014 16781746 12958197 16485898 19923254 17522070 11421492
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.5119426721
MESH:D005756 Gastritis Acetaminophen 5.0916983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1516870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4715629191 12587719
MESH:D008107 Liver Diseases Acetaminophen 1.7219784758 12969438 11587558 16611625 12587719 19014921 16610002 19460945
MESH:D017114 Liver Failure, Acute Acetaminophen 3.8116871587 17185352
MESH:D008546 Melanoma, Experimental Acetaminophen 4.4719513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3618514411
MESH:D010146 Pain Acetaminophen 2.8716870215
MESH:D014581 Urticaria Acetaminophen 3.6710982225
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018