Annotation Detail for SMARCD3
Basic Information
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| Gene Symbol: | SMARCD3 ( BAF60C,CRACD3,MGC111010,Rsc6p ) |
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| Gene Full Name: | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
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| Band: | 7q36.1 |
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| Quick Links | Entrez ID:6604; OMIM: 601737; Uniprot ID:SMRD3_HUMAN; ENSEMBL ID: ENSG00000082014; HGNC ID: 11108 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| Metabolism of lipids and lipoproteins |
| Pathway ID | Pathway Name |
|---|
| 200061 | LKB1 signaling events |
| Pathway ID | Pathway Name |
|---|
| P00057 | Wnt signaling pathway |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D017638 |
Asbestos, Crocidolite |
Asbestos, Crocidolite affects the expression of SMARCD3 mRNA | affects expression | 17331233
|
| D016572 |
Cyclosporine |
Cyclosporine results in decreased expression of SMARCD3 mRNA | decreases expression | 20106945
|
| C008493 |
methylselenic acid |
methylselenic acid results in increased expression of SMARCD3 mRNA | increases expression | 18548127
|
| C006253 |
pirinixic acid |
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of SMARCD3 mRNA | affects binding|increases activity|increases expression | 19710929
|
| D012643 |
Selenium |
Selenium results in increased expression of SMARCD3 mRNA | increases expression | 19244175
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.52 | 18653653 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
4.02 | 16434500 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.52 | 19483382 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
Cyclosporine |
2.76 | 12371664 |
| MESH:D002779 |
Cholestasis |
|
Cyclosporine |
8.63 | 19486331 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
8.63 | 19176532 |
| MESH:D003092 |
Colitis |
|
Selenium |
4.26 | 17936198 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.56 | 18249437 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Selenium |
2.25 | 15131321 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
2.85 | 12083418 |
| MESH:D005234 |
Fatty Liver |
|
Cyclosporine |
8.82 | 19224547 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
8.82 | 19236843 20131406 |
| MESH:D005355 |
Fibrosis |
|
Cyclosporine |
3.62 | 12639820 12168785 |
| MESH:D005885 |
Gingival Hyperplasia |
|
Cyclosporine |
4.76 | 8708960 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
7.62 | 20558911 |
| MESH:D006333 |
Heart Failure |
|
Selenium |
7.62 | 17162251 |
| MESH:D006457 |
Hemoglobinuria, Paroxysmal |
|
Cyclosporine |
4.96 | 15720958 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.48 | 18467677 19772884 16221962 19176532 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.53 | 20558911 |
| MESH:D006973 |
Hypertension |
|
Cyclosporine |
2.20 | 10903974 |
| MESH:D007251 |
Influenza, Human |
|
Selenium |
4.81 | 16624496 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.85 | 16306350 |
| MESH:D007638 |
Keratoconjunctivitis Sicca |
|
Cyclosporine |
5.05 | 15604871 |
| MESH:D007674 |
Kidney Diseases |
|
Cyclosporine |
2.52 | 18776723 10903974 8314463 |
| MESH:D007676 |
Kidney Failure, Chronic |
|
Selenium |
4.26 | 16518626 |
| MESH:D007680 |
Kidney Neoplasms |
|
Cyclosporine |
3.04 | 12371664 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
1.92 | 15890375 16377806 20007298 |
| MESH:D055370 |
Lung Injury |
|
Asbestos, Crocidolite |
4.50 | 17365036 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Selenium |
2.97 | 15318939 |
| MESH:D008654 |
Mesothelioma |
|
Asbestos, Crocidolite |
6.72 | 16166281 16966607 18303189 |
| MESH:D008654 |
Mesothelioma |
|
Selenium |
6.72 | 15107826 |
| MESH:D008664 |
Metal Metabolism, Inborn Errors |
|
Cyclosporine |
5.40 | 16801185 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
3.99 | 16239165 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.26 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.22 | 16411023 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.09 | 17405874 |
| MESH:D009402 |
Nephrosis, Lipoid |
|
Cyclosporine |
5.05 | 17954296 |
| MESH:D009404 |
Nephrotic Syndrome |
|
Cyclosporine |
3.61 | 19348381 18481113 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
1.88 | 20558911 |
| MESH:D010954 |
Plasmacytoma |
|
Selenium |
5.50 | 15087411 |
| MESH:D010995 |
Pleural Diseases |
|
Asbestos, Crocidolite |
5.38 | 10923243 |
| MESH:D011230 |
Precancerous Conditions |
|
Cyclosporine |
3.55 | 12371664 |
| MESH:D011471 |
Prostatic Neoplasms |
|
methylselenic acid |
3.84 | 16205645 |
| MESH:D011565 |
Psoriasis |
|
Cyclosporine |
2.32 | 16882103 |
| MESH:D011658 |
Pulmonary Fibrosis |
|
Asbestos, Crocidolite |
3.14 | 17365031 15814490 17322281 17975199 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.53 | 19058328 |
| MESH:D014605 |
Uveitis |
|
Cyclosporine |
4.59 | 1336536 |
| MESH:D014985 |
Xerophthalmia |
|
Cyclosporine |
5.05 | 17120751 |
| Pathway ID |
Pathway Name |
|---|
| REACT:22258 |
Metabolism of lipids and lipoproteins |
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