AutismKB 2.0

Annotation Detail for SNRPG


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Basic Information Top
Gene Symbol:SNRPG ( MGC117317,SMG,Sm-G )
Gene Full Name: small nuclear ribonucleoprotein polypeptide G
Band: 2p13.3
Quick LinksEntrez ID:6637; OMIM: 603542; Uniprot ID:RUXG_HUMAN; ENSEMBL ID: ENSG00000143977; HGNC ID: 11163
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa03040Spliceosome
Pathway IDPathway Name
Post-Elongation Processing of the Transcript
Transcription
Metabolism of RNA
mRNA Processing
Gene Expression
No data
No data
Pathway IDPathway Name
500858snRNP Assembly
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in decreased expression of SNRPG mRNAdecreases expression 12958071
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of SNRPG mRNAdecreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of SNRPG mRNAaffects expression 17562736
C099555 CD 437 CD 437 results in decreased expression of SNRPG mRNAdecreases expression 12958071
D006830 Hydralazine [Hydralazine co-treated with Valproic Acid] results in increased expression of SNRPG mRNAaffects cotreatment|increases expression 17183730
C006253 pirinixic acid pirinixic acid results in increased expression of SNRPG mRNAincreases expression 18301758
D014635 Valproic Acid [Hydralazine co-treated with Valproic Acid] results in increased expression of SNRPG mRNAaffects cotreatment|increases expression 17183730
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 3.888875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 4.2119490988
MESH:D055371 Acute Lung Injury pirinixic acid 3.4218653653
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.903712494
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.8816434500
MESH:D000550 Amblyopia Valproic Acid 5.6817688650
MESH:D000799 Angioedema Acetaminophen 4.2910982225
MESH:D001008 Anxiety Disorders Valproic Acid 3.7917497229
MESH:D001321 Autistic Disorder Acetaminophen 1.8618445737
MESH:D001321 Autistic Disorder Valproic Acid 1.8618316065 18396377 17507914 18177632 17157402 18985861 16609825 18775368 15238991 18940202 19460635 19232924 18558336 20603192 17688650
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.4611289319 1440618
MESH:D001714 Bipolar Disorder Valproic Acid 3.2017594078 20046352
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.4319483382
MESH:D001848 Bone Diseases, Developmental Valproic Acid 3.578888407
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 2.927296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 2.923084413
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.787296757
MESH:D002386 Cataract Acetaminophen 2.7310977129
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 2.947505956
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.7920734317
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 8.529022650 19486331
MESH:D002779 Cholestasis pirinixic acid 8.5219176532
MESH:D019465 Craniofacial Abnormalities Valproic Acid 1.9016575769 17688650 8888407
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 3.1511906362 11298694 14531868 8970840 12868966 18759878 8156756 2524372
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5318249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.793621924 2952479
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 6.6016192314 9022650 6679447 18289764 1440618 9653073 18692083 6482804 9328219 7440962 18648102 8291058 11289319
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.6014550746 12958197 11739529 17562736 14725611 16485898 12540782 18071297 12392966 16227642 16781746 11834606 11287661 11421492 10915739 14986274 17906064 19370779 11529661 11461765 15619225 19085960 19739265 19164858 12705907 15968718 19420014 12594235 12153990 19416960 10774834 16109766 2444490 17522070 18713872 16081117 19923254 16177239 11743745 16393943 10663392
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 6.601733752 19641884
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.5419426721
MESH:D004421 Dystonia Valproic Acid 4.351851702
MESH:D004487 Edema pirinixic acid 2.7612083418
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.513659116 17275665
MESH:D004828 Epilepsies, Partial Valproic Acid 4.3616628512 3922381
MESH:D004827 Epilepsy Valproic Acid 3.0620417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 3.846254150 7562514 6426943
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.667750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.463659116
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.163581430
MESH:D005234 Fatty Liver pirinixic acid 8.6820131406 19236843
MESH:D005234 Fatty Liver Valproic Acid 8.6819224547 14986274
MESH:D005315 Fetal Diseases Valproic Acid 5.3316575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.4618558336 8888407
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.466705139
MESH:D005756 Gastritis Acetaminophen 4.1216983495
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.347505956
MESH:D006333 Heart Failure pirinixic acid 2.6920558911
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.846705139
MESH:D006529 Hepatomegaly pirinixic acid 3.3519772884 18467677 19176532 16221962
MESH:D006849 Hydrocephalus Valproic Acid 5.2617688650
MESH:D006930 Hyperalgesia Acetaminophen 2.9216870215
MESH:D006943 Hyperglycemia pirinixic acid 3.4520558911
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.3015034207
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 4.9816612254
MESH:D007333 Insulin Resistance pirinixic acid 2.8016306350
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.468074119 9022650
MESH:D007674 Kidney Diseases Acetaminophen 2.3415629191 12587719
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 3.206582329
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.1916294345 17596541
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.3515034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008107 Liver Diseases Acetaminophen 1.6819460945 12969438 12587719 19014921 11587558 16611625 16610002 19784758
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5016871587 17185352
MESH:D008113 Liver Neoplasms pirinixic acid 1.9020007298 15890375 16377806
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 2.691399818 598648 6587162 3712494
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.7017228818
MESH:D008546 Melanoma, Experimental Acetaminophen 3.9319513568
MESH:D008881 Migraine Disorders Valproic Acid 3.3818803445 18765137
MESH:D009135 Muscular Diseases pirinixic acid 3.8616239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.318888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.3017596541
MESH:D009203 Myocardial Infarction pirinixic acid 2.2419151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.1616411023
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.563581430
MESH:D009369 Neoplasms pirinixic acid 2.0617405874
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 7.826679447
MESH:D009436 Neural Tube Defects Valproic Acid 7.8216359493 8888407
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1018514411
MESH:D009765 Obesity pirinixic acid 1.8620558911
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.684026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.463988306
MESH:D010051 Ovarian Neoplasms CD 437 3.3817474084
MESH:D010146 Pain Acetaminophen 2.6216870215
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.847296757
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.916228378
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 4.2320603192
MESH:D019310 Pseudolymphoma Valproic Acid 4.9811422049 12752131
MESH:D015427 Reperfusion Injury pirinixic acid 2.5019058328
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.583692021
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.4819155313
MESH:D012559 Schizophrenia Valproic Acid 2.0915737665 19110320
MESH:D012640 Seizures Valproic Acid 2.9111738929 14763951 3137016 16876388 17978042 15475178 1511512 11044598
MESH:D016135 Spinal Dysraphism Valproic Acid 3.9919490988
MESH:D013226 Status Epilepticus Valproic Acid 4.9812833885
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 3.096582329 3712494 7505956 6587162 1399818
MESH:D014178 Translocation, Genetic Valproic Acid 5.6817262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.923119515
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 5.728074119
MESH:D001749 Urinary Bladder Neoplasms CD 437 5.7216720286
MESH:D014564 Urogenital Abnormalities Valproic Acid 5.008888407
MESH:D014581 Urticaria Acetaminophen 3.2810982225
Pathway ID Pathway Name
REACT:71 Gene Expression
REACT:21257 Metabolism of RNA
REACT:1675 mRNA Processing
REACT:78 Post-Elongation Processing of the Transcript
KEGG:03040 Spliceosome
REACT:1788 Transcription
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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