AutismKB 2.0

Annotation Detail for SOAT1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SOAT1 ( ACACT,ACAT,ACAT1,RP11-215I23.2,SOAT,STAT )
Gene Full Name: sterol O-acyltransferase 1
Band: 1q25.2
Quick LinksEntrez ID:6646; OMIM: 102642; Uniprot ID:SOAT1_HUMAN; ENSEMBL ID: ENSG00000057252; HGNC ID: 11177
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa00100Steroid biosynthesis
No data
No data
Pathway IDPathway Name
P02727Androgen/estrogene/progesterone biosynthesis
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1740Alzheimer's disease
1766Renal Cell cancer
2120Rabies
Desease Name
Alzheimer's disease
NEUROLOGICAL
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C021296 2-ethoxyethanol 2-ethoxyethanol results in increased expression of SOAT1 mRNAincreases expression 19643169
C105260 4-tert-octylphenol 4-tert-octylphenol results in increased expression of SOAT1 mRNAincreases expression 17011747
D000082 Acetaminophen Acetaminophen affects the expression of SOAT1 mRNAaffects expression 17562736
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of SOAT1 proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride affects the expression of SOAT1 mRNAaffects expression 16483693
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of SOAT1 mRNAincreases expression 15336504
C055494 caffeic acid phenethyl ester [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SOAT1 mRNAaffects cotreatment|decreases expression 20360939
D002995 Clofibric Acid Clofibric Acid affects the expression of SOAT1 mRNAaffects expression 17602206
D003520 Cyclophosphamide SOAT1 protein affects the susceptibility to Cyclophosphamideaffects response to substance 16217747
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SOAT1 mRNAaffects cotreatment|decreases expression 20360939
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of SOAT1 mRNAincreases expression 19638242
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of SOAT1 mRNAincreases expression 17011747
D015525 Fatty Acids, Omega-3 Fatty Acids, Omega-3 results in decreased expression of SOAT1 mRNAdecreases expression 16823509
D005472 Fluorouracil SOAT1 protein affects the susceptibility to Fluorouracilaffects response to substance 16217747
C005219 methyl cellosolve methyl cellosolve results in increased expression of SOAT1 mRNAincreases expression 19643169
D043371 Fatty Acids, Omega-6 Fatty Acids, Omega-6 results in increased expression of SOAT1 mRNAincreases expression 16823509
C023036 perfluorooctanoic acid perfluorooctanoic acid results in increased expression of SOAT1 mRNAincreases expression 17681415
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of SOAT1 mRNAincreases expression 19465110
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 2-ethoxyethanol 14.497151721 6499796 6499823 6499812 6499820
MESH:D000014 Abnormalities, Drug-Induced methyl cellosolve 14.496499812 6474471 3652986
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 14.4914514962 11752688 15322242
MESH:D000138 Acidosis Ammonium Chloride 3.5518287403
MESH:D000230 Adenocarcinoma Fluorouracil 2.4217638652
MESH:D000236 Adenoma Diethylnitrosamine 2.8410737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 10.0318056438 19052882 17162532 19061943 16434500 17620307
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 10.0316835633
MESH:D000686 Amyloidosis Diethylstilbestrol 4.4615469931
MESH:D000740 Anemia Fluorouracil 8.6215504547 16511603 17963324
MESH:D000740 Anemia Tetrachlorodibenzodioxin 8.6211748828
MESH:D000748 Anemia, Macrocytic methyl cellosolve 6.353699323
MESH:D000799 Angioedema Acetaminophen 3.8410982225
MESH:D001161 Arteriosclerosis Cyclophosphamide 4.5815014928
MESH:D053627 Asthenozoospermia 2-ethoxyethanol 12.586499823 10689203 6499807
MESH:D053627 Asthenozoospermia methyl cellosolve 12.583987992
MESH:D001259 Ataxia 2-ethoxyethanol 5.447151721
MESH:D001284 Atrophy 2-ethoxyethanol 11.3615850284 6499799
MESH:D001284 Atrophy methyl cellosolve 11.363699323 2626667 6705890
MESH:D001289 Attention Deficit Disorder with Hyperactivity Fatty Acids, Omega-3 9.2218448859
MESH:D001289 Attention Deficit Disorder with Hyperactivity Fatty Acids, Omega-6 9.2218448859
MESH:D001321 Autistic Disorder Acetaminophen 2.4018445737
MESH:D001321 Autistic Disorder Fatty Acids, Omega-3 2.4016920077
MESH:D053713 Azoospermia 2-ethoxyethanol 5.566499807 6492198
MESH:D001724 Birth Weight 2-ethoxyethanol 6.516499823 2884743
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.0212125929
MESH:D001836 Body Weight Changes 2-ethoxyethanol 12.036499796 7151721
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 12.0315340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7515746008
MESH:D001943 Breast Neoplasms Cyclophosphamide 2.3415093573 11325840 15136595 12006526 16978400 18234424 17020986 18323546 17388661
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.3417474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 2.3417129689 15324884
MESH:D001943 Breast Neoplasms Fluorouracil 2.3416110121 16595493 18357371 16557594 18608205 19217205 15136595
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.3420435547
MESH:D002276 Carcinoid Tumor Fluorouracil 4.6716051944
MESH:D002277 Carcinoma Fluorouracil 8.1317121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 8.1316835633
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 11.373084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 11.3721507988 12619106 12907637
MESH:D006528 Carcinoma, Hepatocellular Cyclophosphamide 11.3719701751
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 11.3718056438 16288022 16502159 19052882 16878318 18978308 16328049 21159647 17055752 18506893 19418558 19822196 18691550 17978847 18210153 20084675 16681979 19701751 10737359 19394651 20432363 19335982 20727157 3581430 19208518 19519916 16935385 18494052 16569478 19107877 18665156 18785209 20214788 16807293 10672840 20524982 18788625 16830150 20514400 20007298 3084413 17761372 18971187 20512989 19919837 16540662 20935162 19539802 17138121 16698587 19171122 17428255 20101231 17162532 18393292 11831363 16779866 17173139 19383236
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 11.3715948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 11.3717045692 16332177 17088986 18930000 17971768 16799960
MESH:D018827 Carcinoma, Lewis Lung Cyclophosphamide 4.8816152834
MESH:D002292 Carcinoma, Renal Cell Cyclophosphamide 6.7816201981
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 6.7818695887
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 2.4918986760 16757204 17066447 16280240
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3518850075 16120746 18670907
MESH:D002386 Cataract Acetaminophen 2.5710977129
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 2.8417174075 2727394 21159647 7505956
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 9.2619052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 9.2616835633
MESH:D002764 Cholecystitis 2-ethoxyethanol 13.656499794
MESH:D002764 Cholecystitis methyl cellosolve 13.656499794
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0915668235 12621046 15340226 16354765 8697196
MESH:D003110 Colonic Neoplasms Fluorouracil 2.2317287894 17725105 17016597 18772588 17169374 16510598 17172411 15001691 16340194 17018589
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.0015148649 18383874 18448328 16391804 16331619 16524972 14970324 16282729 17454858 17695437 18949393 18802399 18288408 20501625 17094418 17255274 16303861 17401013 17594712 15289873 17016601 18509181
MESH:D000013 Congenital Abnormalities methyl cellosolve 9.376499821 12530607
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 9.3717141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2515322242 20055451 10048152
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.5416002989 12952375
MESH:D003556 Cystitis Cyclophosphamide 4.9918295254 15276878 17979934 15643279 10498854 18710439 12388444 10700343 18372110 18093676 11948286 12161096 16989017 18433785 18483878 12913760 16614059 16413132 17010015 16651033
MESH:D007644 Darier Disease Fluorouracil 4.7816733453
MESH:D003643 Death 2-ethoxyethanol 5.966499796
MESH:D003921 Diabetes Mellitus, Experimental Cyclophosphamide 4.0515331540 10990075 11751995
MESH:D003922 Diabetes Mellitus, Type 1 Cyclophosphamide 3.2118772604
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.2020387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.2017107852
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.0916177239 19416960 16393943 12540782 16227642 16781746 19739265 14550746 14986274 11529661 12594235 14725611 11287661 10663392 11834606 18713872 19370779 10774834 19420014 11743745 16081117 11739529 12705907 11461765 15619225 12153990 17906064 11421492 19923254 12958197 2444490 12392966 17562736 18071297 16109766 17522070 10915739 19164858 15968718 19085960 16485898
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 6.0919107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.0920420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.1019426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7411462148
MESH:D004487 Edema perfluorooctanoic acid 6.8817259670 12083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.8811000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.9018230668 15322242 16714409
MESH:D020964 Embryo Loss 2-ethoxyethanol 6.516499796
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 4.6816402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 3.4515700306 16804899
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.009294722 10568697
MESH:D004802 Eosinophilia Cyclophosphamide 4.2011006010
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.1216302075
MESH:D004938 Esophageal Neoplasms Fluorouracil 2.4416785472 17638652 16481741 16337965 15173087
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.0011564622
MESH:D005234 Fatty Liver Diethylnitrosamine 3.1720387270 21071580
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.6416611131 15751030 16534752 16513791 16002989
MESH:D005313 Fetal Death 2-ethoxyethanol 10.806499820 7151721 6499823 7198755 2884743
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 10.8011858732
MESH:D005317 Fetal Growth Retardation 2-ethoxyethanol 5.396499796
MESH:D005327 Fetal Resorption 2-ethoxyethanol 12.676499820 6499812
MESH:D005327 Fetal Resorption methyl cellosolve 12.676499812 6499821 3987992 6474471
MESH:D020567 Fetal Weight 2-ethoxyethanol 13.656499820 7151721 2884743
MESH:D020567 Fetal Weight methyl cellosolve 13.656499821 6474471 6499812
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 2.9320067830
MESH:D005532 Foot Deformities, Congenital methyl cellosolve 5.463652986
MESH:D005756 Gastritis Acetaminophen 3.6816983495
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.9416452187
MESH:D005910 Glioma Fluorouracil 2.8616145905
MESH:D018316 Gliosarcoma Cyclophosphamide 5.5111389073
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5910696789
MESH:D006086 Graft vs Host Disease Cyclophosphamide 5.0215172196 11014644 16376943
MESH:D006258 Head and Neck Neoplasms Fluorouracil 3.3718337622 15102660 15162350
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.3211294989 10048152
MESH:D006345 Heart Septal Defects, Ventricular methyl cellosolve 5.776499821
MESH:D006402 Hematologic Diseases 2-ethoxyethanol 5.3710514026 20172899
MESH:D006461 Hemolysis 2-ethoxyethanol 12.3419051582 17874071
MESH:D006461 Hemolysis methyl cellosolve 12.3417874071
MESH:D006467 Hemophilia A Cyclophosphamide 5.2811918545
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3211000095
MESH:D006504 Hepatic Veno-Occlusive Disease Cyclophosphamide 5.5314986274
MESH:D006529 Hepatomegaly perfluorooctanoic acid 8.623609246
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 8.6212621046 15340226 16120746
MESH:D006689 Hodgkin Disease Cyclophosphamide 3.7716135485 17606976
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.058697196 16959395 16354765 18606429 15340226
MESH:D006930 Hyperalgesia Acetaminophen 7.8016870215
MESH:D006930 Hyperalgesia perfluorooctanoic acid 7.8012083418
MESH:D006965 Hyperplasia Diethylstilbestrol 4.4214722030 12960047
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9018850075 18670907
MESH:D007021 Hypospadias Diethylstilbestrol 4.5716002989
MESH:D007154 Immune System Diseases Cyclophosphamide 5.3316076520
MESH:D007246 Infertility Diethylstilbestrol 4.3415036965
MESH:D007247 Infertility, Female 2-ethoxyethanol 5.216499823
MESH:D007248 Infertility, Male 2-ethoxyethanol 11.596499823
MESH:D007248 Infertility, Male Cyclophosphamide 11.597193160 16517039
MESH:D007248 Infertility, Male methyl cellosolve 11.593987992
MESH:D007249 Inflammation Diethylnitrosamine 11.9718785209
MESH:D007249 Inflammation Fatty Acids, Omega-3 11.9717296493
MESH:D007249 Inflammation perfluorooctanoic acid 11.9712083418
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 11.9712200463 12878042
MESH:D007414 Intestinal Neoplasms caffeic acid phenethyl ester 4.5710783313
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.3216580747
MESH:D007674 Kidney Diseases Acetaminophen 6.2015629191 12587719
MESH:D007674 Kidney Diseases caffeic acid phenethyl ester 6.2015369732
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 7.6015003126 16762066 14681315
MESH:D007680 Kidney Neoplasms Fluorouracil 7.6016985049
MESH:D007859 Learning Disorders Diethylstilbestrol 4.0517184923
MESH:D007938 Leukemia Cyclophosphamide 3.4810602166
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Cyclophosphamide 3.4917008537 17296974 17658394 18587576 18172266 17802794
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Cyclophosphamide 4.0710373061
MESH:D015473 Leukemia, Promyelocytic, Acute caffeic acid phenethyl ester 3.9816766008
MESH:D007970 Leukopenia Cyclophosphamide 4.9611830472 10052129
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 5.228812269
MESH:D017880 Limb Deformities, Congenital methyl cellosolve 4.486499821
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.8120032147 18665156 18407596 19638242 18522880
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 1.2412878042
MESH:D008107 Liver Diseases Acetaminophen 3.8911587558 19784758 19460945 12969438 12587719 16611625 16610002 19014921
MESH:D008107 Liver Diseases Diethylnitrosamine 3.8917034775
MESH:D017114 Liver Failure, Acute Acetaminophen 3.2217185352 16871587
MESH:D008113 Liver Neoplasms Aflatoxin B1 21.812125692 9163691 18177683 15890375
MESH:D008113 Liver Neoplasms Clofibric Acid 21.8117602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 21.8119090486 21047994 19551842 12771043 20501860 2862719 18648771 15885732 19294768 19255062 19254457 19850985 18644402 20434301 20101389 20405173 18977376 10737359 18978307 20492335 15175105 18754104 20118626 19073162 2422723 19812893 19638242 19642983 16942905 21071580 21167192 19690152 12112319 20452335 19256749 19427195 9163691 19499222 20583210 20137499 19833225 19996281 21278145 19426721
MESH:D008113 Liver Neoplasms Diethylstilbestrol 21.8115890375 16712894
MESH:D008113 Liver Neoplasms Fluorouracil 21.8118383874 15113037 17045692 16603448
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 21.8114757943 18709148
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 21.8116984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 9.748603461
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 9.7419539802 9362446 16267830 19126423 2563599 17854601 19009564 17942915 19519916 18079962 19004024 21159647 17174075 18308698 18775883 18164116 18544905 18282651 16842330 18093689 18253720 3124819
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 9.7412151625
MESH:D008175 Lung Neoplasms Aflatoxin B1 4.8314755239
MESH:D008175 Lung Neoplasms Diethylnitrosamine 4.836695378 20970405 20512841 21163286
MESH:D008175 Lung Neoplasms Fluorouracil 4.8315246190
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.8319555203 11884234
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.7815086387
MESH:D008181 Lupus Nephritis Diethylstilbestrol 5.1415166399
MESH:D008223 Lymphoma Cyclophosphamide 7.8312854902
MESH:D008223 Lymphoma Diethylstilbestrol 7.8315700306
MESH:D016393 Lymphoma, B-Cell Cyclophosphamide 4.5816675587
MESH:D008228 Lymphoma, Non-Hodgkin Cyclophosphamide 4.1511911406
MESH:D008231 Lymphopenia methyl cellosolve 5.773699323
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.5216002989
MESH:D008546 Melanoma, Experimental Acetaminophen 10.7919513568
MESH:D008546 Melanoma, Experimental Cyclophosphamide 10.7916388313
MESH:D009062 Mouth Neoplasms Fluorouracil 3.6116757204 18986760
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0012213967
MESH:D009336 Necrosis 2-ethoxyethanol 5.3420172899
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.569029167 3581430
MESH:D009369 Neoplasms Cyclophosphamide 8.4018854779
MESH:D009369 Neoplasms Diethylstilbestrol 8.4015313581
MESH:D009369 Neoplasms Fluorouracil 8.4018600527 18239605 16928823
MESH:D009421 Nervous System Malformations Diethylstilbestrol 9.5911399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.5914600291
MESH:D009447 Neuroblastoma Cyclophosphamide 3.638761367 15176712 16115947
MESH:D019636 Neurodegenerative Diseases Acetaminophen 8.1218514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 8.1220387270
MESH:D017599 Neuroectodermal Tumors Cyclophosphamide 4.888761367 12837982
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.1220387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.4216436463
MESH:D009503 Neutropenia Cyclophosphamide 4.318291058
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 4.949802331
MESH:D009845 Oligospermia 2-ethoxyethanol 18.1220172899
MESH:D009845 Oligospermia Cyclophosphamide 18.1216517039
MESH:D009845 Oligospermia methyl cellosolve 18.123987992
MESH:D010146 Pain Acetaminophen 6.7916870215
MESH:D010146 Pain Cyclophosphamide 6.7918093676 12161096
MESH:D010190 Pancreatic Neoplasms Cyclophosphamide 8.6911332152
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 8.6916540662
MESH:D010190 Pancreatic Neoplasms Fluorouracil 8.6916500647 16929163 15113037 19003803
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.2512520081
MESH:D010900 Pituitary Diseases Diethylstilbestrol 5.1714722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.6616977796 15687265
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5418163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.532563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Cyclophosphamide 3.7921297632
MESH:D011297 Prenatal Exposure Delayed Effects 2-ethoxyethanol 30.477198755 6499817 2884743
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 30.4717184923
MESH:D011297 Prenatal Exposure Delayed Effects methyl cellosolve 30.4712530607 7974496 6499817
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 30.4717132714
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 30.4711118676 11399792 11222880 11896295
MESH:D011471 Prostatic Neoplasms Cyclophosphamide 2.7417136230
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 2.7417136230 15846301 15046698
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.7418626508 19082440
MESH:D011658 Pulmonary Fibrosis Cyclophosphamide 3.2716636934
MESH:D012004 Rectal Neoplasms Fluorouracil 3.9915538739 18286688 18722050 16160472
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8218990726
MESH:D012595 Scleroderma, Systemic Cyclophosphamide 4.8016636934
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 5.568532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.5616192470
MESH:D013088 Spermatocele Diethylstilbestrol 4.7116709447 16002989
OMIM:102530 SPERMATOGENIC FAILURE 6 Cyclophosphamide 5.5116517039
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.4918456281
MESH:D013274 Stomach Neoplasms Fluorouracil 2.4917172411 18567086 19084572 18396642 19015929 16424979 16951190 15786421 17522103 17498489
MESH:D013276 Stomach Ulcer 2-ethoxyethanol 4.366499799
MESH:D015173 Supratentorial Neoplasms Cyclophosphamide 5.0512837982
MESH:D013733 Testicular Diseases 2-ethoxyethanol 11.0410514026 6499806 10048760
MESH:D013733 Testicular Diseases methyl cellosolve 11.046499806
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.9012697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 2.977505956
MESH:D014062 Tongue Neoplasms Fluorouracil 3.9716280240
MESH:D001749 Urinary Bladder Neoplasms Cyclophosphamide 5.4814692829
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 5.4816452187 16712894 17306315
MESH:D014581 Urticaria Acetaminophen 2.9610982225
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 9.5216175088
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 9.5216803524
MESH:D014591 Uterine Diseases Diethylstilbestrol 5.1714652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 4.0515809267 16690809
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.4216513791 16002989
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5912125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.2515886252
Pathway ID Pathway Name
KEGG:00330 Arginine and proline metabolism
KEGG:01100 Metabolic pathways
KEGG:00100 Steroid biosynthesis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA36015
    • No data
    Releated disease ID Related disease Name
    PA444516Hypercholesterolemia
    PA444528Hyperlipidemias
    No data
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00973 antagonist Inegy Anticholesteremic Agents;Cholesterol Absorption Inhibitors
    DB01094 antagonist Hesperetin Anticholesteremic Agents
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


    Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved