AutismKB 2.0

Annotation Detail for BNIP3L


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Basic Information Top
Gene Symbol:BNIP3L ( BNIP3a,NIX )
Gene Full Name: BCL2/adenovirus E1B 19kDa interacting protein 3-like
Band: 8p21.2
Quick LinksEntrez ID:665; OMIM: 605368; Uniprot ID:BNI3L_HUMAN; ENSEMBL ID: ENSG00000104765; HGNC ID: 1085
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
200101Direct p53 effectors
No data
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of BNIP3L mRNAaffects expression 21346803
C029955 2-nitrotoluene 2-nitrotoluene results in increased expression of BNIP3L mRNAincreases expression 16460773
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of BNIP3L mRNAincreases expression 18648102
C105260 4-tert-octylphenol 4-tert-octylphenol results in decreased expression of BNIP3L mRNAdecreases expression 17011747
C105260 4-tert-octylphenol 4-tert-octylphenol results in increased expression of BNIP3L mRNAincreases expression 17011747
C430898 AGN 194204 AGN 194204 results in increased expression of BNIP3L mRNAincreases expression 16339527
D000643 Ammonium Chloride Ammonium Chloride affects the expression of BNIP3L mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in increased expression of BNIP3L mRNAincreases expression 15592527
C006632 arsenic trioxide arsenic trioxide results in increased expression of BNIP3L proteinincreases expression 15592527
C015001 arsenite arsenite results in increased expression of BNIP3L mRNAincreases expression 18585952
C015001 arsenite XPA protein affects the reaction [arsenite results in increased expression of BNIP3L mRNA]affects reaction|increases expression 18585952
D017638 Asbestos, Crocidolite Asbestos, Crocidolite affects the expression of BNIP3L mRNAaffects expression 17331233
C005961 bis(tri-n-butyltin)oxide bis(tri-n-butyltin)oxide results in decreased expression of BNIP3L mRNAdecreases expression 17553608
C099813 bromochloroacetic acid bromochloroacetic acid results in increased expression of BNIP3L mRNAincreases expression 16460773
C018021 cobaltous chloride cobaltous chloride results in increased expression of BNIP3L mRNAincreases expression 15375294
C018021 cobaltous chloride cobaltous chloride results in increased expression of BNIP3L proteinincreases expression 15375294
D003042 Cocaine Cocaine affects the expression of BNIP3L mRNAaffects expression 15681117
D016572 Cyclosporine Cyclosporine results in increased expression of BNIP3L mRNAincreases expression 20106945
C014347 decitabine decitabine affects the methylation of BNIP3L promoteraffects methylation 17488656
D003676 Deferoxamine Deferoxamine results in increased expression of BNIP3L mRNAincreases expression 11832486
D004054 Diethylstilbestrol Diethylstilbestrol results in decreased expression of BNIP3L mRNAdecreases expression 17011747
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of BNIP3L mRNAincreases expression 17011747
D002117 Calcitriol Calcitriol results in increased expression of BNIP3L mRNAincreases expression 16002434
D004958 Estradiol Estradiol affects the expression of BNIP3L mRNAaffects expression 15598610
D004958 Estradiol Estradiol results in decreased expression of BNIP3L mRNAdecreases expression 14664709
D005472 Fluorouracil BNIP3L affects the susceptibility to Fluorouracilaffects response to substance 15067352
D005472 Fluorouracil Fluorouracil results in decreased expression of BNIP3L mRNAdecreases expression 16557594
15109396
16709241
D005472 Fluorouracil Fluorouracil results in increased expression of BNIP3L mRNAincreases expression 17039268
D005492 Folic Acid Folic Acid affects the expression of BNIP3L mRNAaffects expression 17320366
C056507 gemcitabine gemcitabine results in increased expression of BNIP3L mRNAincreases expression 17039268
D007657 Ketone Bodies Ketone Bodies results in increased expression of BNIP3L mRNAincreases expression 16807920
D008244 Lysophosphatidylcholines Lysophosphatidylcholines binds to BNIP3L proteinaffects binding 11997142
C452423 N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine results in increased expression of BNIP3L mRNAincreases expression 16052530
D010126 Ozone Ozone results in decreased expression of BNIP3L mRNAdecreases expression 12763052
D010656 Phenylephrine Phenylephrine results in increased expression of BNIP3L mRNAincreases expression 16291751
C006253 pirinixic acid pirinixic acid results in increased expression of BNIP3L mRNAincreases expression 18301758
D008926 Plicamycin Plicamycin results in decreased expression of BNIP3L mRNAdecreases expression 16291751
D008926 Plicamycin Plicamycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BNIP3L mRNA]decreases reaction|increases expression 16291751
C025299 polyphenols polyphenols results in decreased expression of BNIP3L mRNAdecreases expression 16293270
D013656 Taurocholic Acid Taurocholic Acid results in increased expression of BNIP3L mRNAincreases expression 14530762
D013656 Taurocholic Acid Taurocholic Acid results in increased expression of BNIP3L proteinincreases expression 14530762
C004648 testosterone enanthate testosterone enanthate affects the expression of BNIP3L mRNAaffects expression 17440010
D013755 Tetradecanoylphorbol Acetate Plicamycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BNIP3L mRNA]decreases reaction|increases expression 16291751
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in increased expression of BNIP3L mRNAincreases expression 16291751
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 3.2318287403
MESH:D058186 Acute Kidney Injury Folic Acid 4.0417003819 16595132 16316344
MESH:D055371 Acute Lung Injury pirinixic acid 2.8218653653
MESH:D000230 Adenocarcinoma arsenic trioxide 6.6019825857 11798837
MESH:D000230 Adenocarcinoma Estradiol 6.6011473722
MESH:D000230 Adenocarcinoma Fluorouracil 6.6017638652
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 6.383712494
MESH:D000236 Adenoma Folic Acid 6.3816963246
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.1616434500
MESH:D000544 Alzheimer Disease Folic Acid 4.2917116317
MESH:D000544 Alzheimer Disease Ozone 4.2915513908
MESH:D000686 Amyloidosis Diethylstilbestrol 4.1715469931
MESH:D000740 Anemia Fluorouracil 3.4316511603 15504547 17963324
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 3.8317460149
MESH:D001172 Arthritis, Rheumatoid Ozone 2.4815570426
MESH:D001249 Asthma Ozone 2.5416373670 17854713
MESH:D001321 Autistic Disorder Folic Acid 2.8621388746
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.6911289319 1440618
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 8.0316206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.0319483382
MESH:D001919 Bradycardia Phenylephrine 4.2215306635
MESH:D001943 Breast Neoplasms Calcitriol 4.4511237771
MESH:D001943 Breast Neoplasms decitabine 4.4518320071 19208741
MESH:D001943 Breast Neoplasms Deferoxamine 4.4515993339
MESH:D001943 Breast Neoplasms Diethylstilbestrol 4.4515324884 17129689
MESH:D001943 Breast Neoplasms Estradiol 4.4517261762 12948864 18497071 16675129 19861407 17289903 14630087 17018787
MESH:D001943 Breast Neoplasms Fluorouracil 4.4515136595 16110121 19217205 16595493 18608205 18357371 16557594
MESH:D001943 Breast Neoplasms Folic Acid 4.4516777985
MESH:D001943 Breast Neoplasms gemcitabine 4.4517039268 18382427
MESH:D016535 Bronchial Hyperreactivity Ozone 3.4215516495 14754758 18417511 16777450 19059883 18315731 17626835
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.0311589617
MESH:D002100 Cachexia Ozone 4.4116183385
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.1416111702
MESH:D002276 Carcinoid Tumor Fluorouracil 4.3416051944
MESH:D002277 Carcinoma Fluorouracil 3.3117121937
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 10.6216705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 10.623581430 7296757
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 10.6215553829 15073043 16217749 11135700 14691202
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 10.6215948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Estradiol 10.6216924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 10.6217088986 16799960 18930000 17045692 17971768 16332177
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.5419014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 5.987296757
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 5.9818695887
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.8412490120
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 10.0211237771
MESH:D002294 Carcinoma, Squamous Cell decitabine 10.0219215824
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 10.0217066447 16757204 16280240 18986760
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 10.0218922899
MESH:D006332 Cardiomegaly Phenylephrine 3.3511179087 11754973 17287366 15728586 17124262 16170337
MESH:D002318 Cardiovascular Diseases Folic Acid 3.7316755160
MESH:D002430 Cecal Neoplasms 2-nitrotoluene 5.3914688030
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 14.176135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 14.177505956
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 14.1712371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 14.1718566989
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 12.009022650 19486331
MESH:D002779 Cholestasis Cyclosporine 12.0019486331
MESH:D002779 Cholestasis pirinixic acid 12.0019176532
MESH:D002971 Cleft Lip Folic Acid 3.8121254359
MESH:D002972 Cleft Palate Folic Acid 3.438946559 21254359
MESH:D019970 Cocaine-Related Disorders Cocaine 5.3919606084
MESH:D003110 Colonic Neoplasms arsenite 7.7915037631
MESH:D003110 Colonic Neoplasms decitabine 7.7917616700
MESH:D003110 Colonic Neoplasms Fluorouracil 7.7916340194 17169374 17725105 18772588 16510598 17172411 15001691 17016597 17287894 17018589
MESH:D003110 Colonic Neoplasms polyphenols 7.7916293270
MESH:D015179 Colorectal Neoplasms arsenic trioxide 4.5520501625
MESH:D015179 Colorectal Neoplasms decitabine 4.5518981723
MESH:D015179 Colorectal Neoplasms Fluorouracil 4.5517594712 17016601 17255274 18949393 14970324 16391804 17094418 16282729 16331619 18288408 16524972 18448328 18509181 15289873 16303861 15148649 20501625 17695437 18383874 17454858 18802399 17401013
MESH:D015179 Colorectal Neoplasms Folic Acid 4.5517116713 17245555 17087956 16985020 16963246
MESH:D023903 Coronary Restenosis arsenic trioxide 3.8812609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 1.8710525206
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.2512952375 16002989
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.7018551238
MESH:D007644 Darier Disease Fluorouracil 4.4716733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.8015213294
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 6.2411298694 2524372 18759878 11906362 12868966 8156756 8970840 14531868
MESH:D017449 Dermatitis, Allergic Contact cobaltous chloride 6.2416823706 15059100 11298694
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2718249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.192952479 3621924
MESH:D003924 Diabetes Mellitus, Type 2 Folic Acid 3.0516886840
MESH:D003928 Diabetic Nephropathies Estradiol 3.1419279558
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 5.7318551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 5.739022650 7440962 8291058 1440618 18289764 9328219 18692083 6679447 6482804 11289319 18648102 16192314 9653073
MESH:D056486 Drug-Induced Liver Injury polyphenols 5.7319370779
MESH:D004487 Edema pirinixic acid 6.0512083418
MESH:D004487 Edema Tetradecanoylphorbol Acetate 6.059599246 15177302 8113982 8273558 7812673 11698051 16716910
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 3.6315138306
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.7819294695
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 4.3716402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 11.3716804899 15700306
MESH:D016889 Endometrial Neoplasms Estradiol 11.3718566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Folic Acid 11.3717301261
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 6.743581430
MESH:D004938 Esophageal Neoplasms arsenic trioxide 6.7412903497
MESH:D004938 Esophageal Neoplasms Fluorouracil 6.7415173087 16481741 16785472 16337965 17638652
MESH:D017889 Exfoliation Syndrome Folic Acid 5.1716504073
MESH:D005234 Fatty Liver arsenic trioxide 16.4015073043
MESH:D005234 Fatty Liver arsenite 16.4018296743
MESH:D005234 Fatty Liver Cyclosporine 16.4019224547
MESH:D005234 Fatty Liver pirinixic acid 16.4019236843 20131406
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.4616513791 15751030 16611131 16002989 16534752
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.696705139
MESH:D005355 Fibrosis arsenite 7.8418296743
MESH:D005355 Fibrosis Cyclosporine 7.8412639820 12168785
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.9516904648
MESH:D005756 Gastritis Folic Acid 4.7617171786
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.6216452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.898708960
MESH:D005901 Glaucoma Folic Acid 4.7816504073
MESH:D005910 Glioma Fluorouracil 2.7416145905
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.747505956
MESH:D006258 Head and Neck Neoplasms decitabine 7.1819215824
MESH:D006258 Head and Neck Neoplasms Fluorouracil 7.1815102660 18337622 15162350
MESH:D006330 Heart Defects, Congenital Folic Acid 3.6216524890 17286298
MESH:D006333 Heart Failure pirinixic acid 2.3420558911
MESH:D006394 Hemangiosarcoma 2-nitrotoluene 4.7913678655
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.0915720958
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.216705139
MESH:D006529 Hepatomegaly pirinixic acid 2.6816221962 19772884 18467677 19176532
MESH:D006558 Herpes Genitalis Estradiol 4.7015709030
MESH:D006679 HIV Seropositivity Folic Acid 5.1717209195
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 5.4117440010
MESH:D019584 Hot Flashes Estradiol 3.4217088409
MESH:D006943 Hyperglycemia pirinixic acid 2.9020558911
MESH:D020138 Hyperhomocysteinemia Folic Acid 4.2216395265 16397167 16755160 16433478 16865747
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 9.7715034207
MESH:D006965 Hyperplasia Diethylstilbestrol 9.7712960047 14722030
MESH:D006973 Hypertension Cyclosporine 4.9510903974
MESH:D006973 Hypertension Phenylephrine 4.9512717712 8949925
MESH:D006984 Hypertrophy Phenylephrine 4.2618502941 12791704
MESH:D007021 Hypospadias Diethylstilbestrol 4.2616002989
MESH:D007246 Infertility Diethylstilbestrol 4.0515036965
MESH:D007248 Infertility, Male decitabine 2.9917581917
MESH:D007249 Inflammation polyphenols 5.0416366677
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 5.0411698051 8273558 7562506 7812673 15177302
MESH:D007333 Insulin Resistance Estradiol 6.4916393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 6.4916306350
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.698074119 9022650
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.1115604871
MESH:D007674 Kidney Diseases Cyclosporine 5.318314463 18776723 10903974
MESH:D007674 Kidney Diseases Estradiol 5.3115618244
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 25.6916705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 25.696582329
MESH:D007680 Kidney Neoplasms Cyclosporine 25.6912371664
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 25.6915003126 14681315 16762066
MESH:D007680 Kidney Neoplasms Estradiol 25.6915610895
MESH:D007680 Kidney Neoplasms Fluorouracil 25.6916985049
MESH:D007859 Learning Disorders Diethylstilbestrol 3.7517184923
MESH:D007938 Leukemia arsenic trioxide 5.9015070760
MESH:D007938 Leukemia decitabine 5.9018980019 19235587
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.5117077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.9816972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.1914633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 8.6219077051
MESH:D007951 Leukemia, Myeloid decitabine 8.6218454857 17236224 19117987
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 5.9516467208 17050201 19850784 20471514 16968895
MESH:D015470 Leukemia, Myeloid, Acute decitabine 5.9518704418 19387464 18460780 18206229 17679729 19010910
MESH:D015470 Leukemia, Myeloid, Acute Deferoxamine 5.9520368581
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.1318055864
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.0016112521 15622746 19035177 16891316 16331271 17712046 19642359 15213294 12018890 17869043 17217047 12712474 11468182 9834237 17107899 17649720 15748426 19075265 11161223 16823087 15336539 16330433 12679006 19225113 16966277
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.0416882451
MESH:D008103 Liver Cirrhosis arsenite 3.2418296743
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.9915034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 2.1914716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 2.1915474484
MESH:D008107 Liver Diseases Folic Acid 4.3816877991
MESH:D008107 Liver Diseases polyphenols 4.3816698588
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 12.877678174
MESH:D008113 Liver Neoplasms arsenic trioxide 12.8714682389
MESH:D008113 Liver Neoplasms Diethylstilbestrol 12.8715890375 16712894
MESH:D008113 Liver Neoplasms Fluorouracil 12.8718383874 17045692 16603448 15113037
MESH:D008113 Liver Neoplasms pirinixic acid 12.8716377806 15890375 20007298
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 8.682876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 8.686587162 598648 1399818 3712494
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 8.6820377131
MESH:D008133 Long QT Syndrome arsenic trioxide 3.1115213294
MESH:D008171 Lung Diseases Ozone 3.168266340 19066396
MESH:D055370 Lung Injury Asbestos, Crocidolite 8.1917365036
MESH:D055370 Lung Injury Ozone 8.1920417186
MESH:D008175 Lung Neoplasms arsenic trioxide 6.1511798837 19825857
MESH:D008175 Lung Neoplasms arsenite 6.1516809336
MESH:D008175 Lung Neoplasms Fluorouracil 6.1515246190
MESH:D008175 Lung Neoplasms Ozone 6.157614698 8597069
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 6.1511807781
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.4715086387
MESH:D008180 Lupus Erythematosus, Systemic Folic Acid 3.2417718048
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.8215166399
MESH:D008223 Lymphoma decitabine 6.9619470736
MESH:D008223 Lymphoma Diethylstilbestrol 6.9615700306
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.1816002989
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 5.5511408345 11807958 17203775 16891317
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 5.558985016
MESH:D020149 Manganese Poisoning Estradiol 4.1519453300
MESH:D019767 Maxillofacial Abnormalities Folic Acid 5.3716832597
MESH:D008545 Melanoma decitabine 2.2017785578 16505122
MESH:D008654 Mesothelioma Asbestos, Crocidolite 3.0518303189 16166281 16966607
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.4616801185
MESH:D008679 Metaplasia Ozone 4.7710496685
MESH:D009062 Mouth Neoplasms Fluorouracil 3.3918986760 16757204
MESH:D009101 Multiple Myeloma arsenic trioxide 6.6111468182 19417148 14977855 15949261 19549372
MESH:D009101 Multiple Myeloma decitabine 6.6118172295
MESH:D019042 Muscle Neoplasms 2-nitrotoluene 6.3513678655
MESH:D009135 Muscular Diseases pirinixic acid 3.1916239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.3418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 6.8816882451 16105982
MESH:D009190 Myelodysplastic Syndromes decitabine 6.8819157545 18608210 19010910 16882708
MESH:D009203 Myocardial Infarction Cocaine 5.6318072171
MESH:D009203 Myocardial Infarction pirinixic acid 5.6319151258
MESH:D015428 Myocardial Reperfusion Injury Estradiol 7.4316810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.4316411023
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.5418551238 7678174
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.6516624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.343581430
MESH:D009369 Neoplasms decitabine 10.5317925555 19116145 19470736
MESH:D009369 Neoplasms Diethylstilbestrol 10.5315313581
MESH:D009369 Neoplasms Fluorouracil 10.5316928823 18600527 18239605
MESH:D009369 Neoplasms pirinixic acid 10.5317405874
MESH:D009389 Neovascularization, Pathologic arsenite 9.0715738583
MESH:D009389 Neovascularization, Pathologic Estradiol 9.0717289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.1117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.0119348381 18481113
MESH:D009421 Nervous System Malformations Diethylstilbestrol 8.7811399458
MESH:D009421 Nervous System Malformations Estradiol 8.7816427766 11399458
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 11.026679447
MESH:D009436 Neural Tube Defects arsenic trioxide 11.0210525206
MESH:D009436 Neural Tube Defects Folic Acid 11.0217438019
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.2216436463
MESH:D009503 Neutropenia Folic Acid 4.2116322990
MESH:D009765 Obesity pirinixic acid 1.7320558911
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 7.9516049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 7.956482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.693988306
MESH:D010051 Ovarian Neoplasms arsenic trioxide 7.2716624393 19769630 12452020
MESH:D010051 Ovarian Neoplasms decitabine 7.2719331143 19259094
MESH:D010051 Ovarian Neoplasms Estradiol 7.2719401270
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 15.0415580305
MESH:D010190 Pancreatic Neoplasms decitabine 15.0419294695
MESH:D010190 Pancreatic Neoplasms Fluorouracil 15.0419003803 16500647 16929163 15113037
MESH:D010190 Pancreatic Neoplasms gemcitabine 15.0417440100 18383843 11504793 18992248 16929163
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 15.0415976015
MESH:D010195 Pancreatitis Taurocholic Acid 4.9220035747
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 8.347296757
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 8.3418922899 12065085 18404319 8330346
MESH:D010235 Paraganglioma arsenic trioxide 3.8619927285
MESH:D010538 Peritonitis Ozone 3.8116369182
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.146228378
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.8414722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.3515687265 16977796
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 4.5710923243
MESH:D011014 Pneumonia Ozone 4.0718381685 18929643 18007984
MESH:D011230 Precancerous Conditions Cyclosporine 2.9512371664
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 3.7917184923
MESH:D055728 Primary Myelofibrosis decitabine 4.4117616702
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.4515572423
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.5920887781
MESH:D011471 Prostatic Neoplasms AGN 194204 1.8816000583
MESH:D011471 Prostatic Neoplasms arsenic trioxide 1.8819131511
MESH:D011471 Prostatic Neoplasms Calcitriol 1.8816644109 18247401 16289102 15754350 12479363
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 1.8815046698 15846301 17136230
MESH:D011471 Prostatic Neoplasms Estradiol 1.8816740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 1.8818626508 19082440
MESH:D011565 Psoriasis Cyclosporine 2.1116882103
MESH:D011618 Psychotic Disorders Cocaine 4.5916134406
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 2.9017975199 17365031 15814490 17322281
MESH:D012004 Rectal Neoplasms Fluorouracil 3.7415538739 18286688 16160472 18722050
MESH:D051437 Renal Insufficiency Folic Acid 4.4615728788
MESH:D015427 Reperfusion Injury pirinixic acid 2.2319058328
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.143692021
MESH:D012208 Rhabdomyosarcoma decitabine 4.1019155313
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.6516646077
MESH:D012559 Schizophrenia Folic Acid 2.8516641680
MESH:D012640 Seizures 2,6-dinitrotoluene 5.7018551238
MESH:D012640 Seizures Cocaine 5.7010454489
MESH:D012852 Sinusitis Phenylephrine 4.387327846
MESH:D012871 Skin Diseases Folic Acid 3.1618709164
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 3.1318404319 11807781 8330346 12065085 8985016
MESH:D013088 Spermatocele Diethylstilbestrol 4.3816709447 16002989
MESH:D013118 Spinal Cord Diseases Folic Acid 5.1716361298
MESH:D013274 Stomach Neoplasms arsenic trioxide 4.4917007042
MESH:D013274 Stomach Neoplasms decitabine 4.4919037991
MESH:D013274 Stomach Neoplasms Fluorouracil 4.4917522103 17498489 16424979 15786421 17172411 19015929 19084572 16951190 18396642 18567086
MESH:D013274 Stomach Neoplasms Folic Acid 4.4917171786
MESH:D020521 Stroke Folic Acid 4.0716517955
MESH:D013705 Temporomandibular Joint Disorders polyphenols 4.9217997062
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 15.196582329 6587162 1399818 7505956 3712494
MESH:D013964 Thyroid Neoplasms arsenic trioxide 15.1919014326
MESH:D013964 Thyroid Neoplasms decitabine 15.1917967635
MESH:D013964 Thyroid Neoplasms N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine 15.1916940797
MESH:D013978 Tibial Fractures Estradiol 4.3519048282
MESH:D014062 Tongue Neoplasms Fluorouracil 3.7116280240
MESH:D016171 Torsades de Pointes arsenic trioxide 3.6415213294
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 14.3916049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 14.398074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 14.3912845720 12973940 11780464 20435036
MESH:D001749 Urinary Bladder Neoplasms decitabine 14.3917616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 14.3916712894 17306315 16452187
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 3.9910091137
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 8.6516175088
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 8.6516803524
MESH:D014591 Uterine Diseases Diethylstilbestrol 4.8414652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 3.7616690809 15809267
MESH:D014604 Uveal Neoplasms decitabine 4.5817785578
MESH:D014605 Uveitis Cyclosporine 3.651336536
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.1216513791 16002989
MESH:D014947 Wounds and Injuries Lysophosphatidylcholines 5.7615541073
MESH:D014985 Xerophthalmia Cyclosporine 4.1117120751
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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