AutismKB 2.0

Annotation Detail for SON


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SON ( BASS1,C21orf50,DBP-5,FLJ21099,FLJ33914,KIAA1019,NREBP,SON3 )
Gene Full Name: SON DNA binding protein
Band: 21q22.11
Quick LinksEntrez ID:6651; OMIM: 182465; Uniprot ID:SON_HUMAN; ENSEMBL ID: ENSG00000159140; HGNC ID: 11183
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of SON mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of SON mRNAaffects expression 21346803
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of SON mRNAdecreases expression 18648102
C016601 4-hydroxytamoxifen 4-hydroxytamoxifen results in decreased expression of SON mRNAdecreases expression 16514628
D000082 Acetaminophen Acetaminophen affects the expression of SON mRNAaffects expression 17562736
C109238 acyline acyline results in increased expression of SON mRNAincreases expression 17510436
D001554 Benzene Benzene results in decreased expression of SON mRNAdecreases expression 15878777
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of SON mRNAdecreases expression 19150397
C005961 bis(tri-n-butyltin)oxide bis(tri-n-butyltin)oxide results in decreased expression of SON mRNAdecreases expression 17553608
D020111 Chlorodiphenyl (54% Chlorine) Chlorodiphenyl (54% Chlorine) results in decreased expression of SON mRNAdecreases expression 16934159
C014347 decitabine decitabine results in increased expression of SON mRNAincreases expression 15251184
C014347 decitabine [Tetrachlorodibenzodioxin co-treated with decitabine] results in increased expression of SON mRNAaffects cotreatment|increases expression 15251184
D004958 Estradiol Estradiol results in increased expression of SON mRNAincreases expression 16514628
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of SON mRNAdecreases expression 17557909
C070081 fulvestrant fulvestrant results in decreased expression of SON mRNAdecreases expression 16514628
D007213 Indomethacin Indomethacin results in decreased expression of SON mRNAdecreases expression 16984733
D010758 Phosphorus Phosphorus results in increased expression of SON mRNAincreases expression 17715259
D020849 Raloxifene Raloxifene results in decreased expression of SON mRNAdecreases expression 16514628
D012643 Selenium [Selenium co-treated with Vitamin E] results in decreased expression of SON mRNAaffects cotreatment|decreases expression 19244175
D012643 Selenium Selenium results in decreased expression of SON mRNAdecreases expression 19244175
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with decitabine] results in increased expression of SON mRNAaffects cotreatment|increases expression 15251184
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of SON mRNAincreases expression 15251184
D014810 Vitamin E [Selenium co-treated with Vitamin E] results in decreased expression of SON mRNAaffects cotreatment|decreases expression 19244175
D014810 Vitamin E Vitamin E results in decreased expression of SON mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.7614514962 11752688 15322242
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8617505938
MESH:D000230 Adenocarcinoma Estradiol 6.9811473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 6.9814692618
MESH:D000230 Adenocarcinoma Indomethacin 6.9816537180
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 6.723712494
MESH:D000236 Adenoma Indomethacin 6.7211497255
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.2916835633
MESH:D000419 Albuminuria Raloxifene 4.5117451421 17308373
MESH:D016301 Alveolar Bone Loss Indomethacin 5.2917225004
MESH:D000544 Alzheimer Disease Indomethacin 4.4017627676 15579461
MESH:D000544 Alzheimer Disease Raloxifene 4.4015800139
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8711748828
MESH:D000741 Anemia, Aplastic Benzene 4.3011369114 14761424 17661222
MESH:D000799 Angioedema Acetaminophen 3.7610982225
MESH:D001014 Aortic Aneurysm Indomethacin 4.7610231640
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 4.7810388637
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.3811256880
MESH:D018771 Arthralgia Indomethacin 5.092160914
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6115885639
MESH:D001172 Arthritis, Rheumatoid Indomethacin 2.8011248219
MESH:D001284 Atrophy fulvestrant 4.7611514358
MESH:D001321 Autistic Disorder Acetaminophen 1.4318445737
MESH:D001477 Bartter Syndrome Indomethacin 4.9010684365
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.9411289319 1440618
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 2.9612125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7115746008
MESH:D001855 Bone Marrow Diseases Benzene 5.1516183116
MESH:D001929 Brain Edema Indomethacin 4.9411481608
MESH:D001930 Brain Injuries Raloxifene 4.3916580743
MESH:D002545 Brain Ischemia Indomethacin 4.3312524144
MESH:D001943 Breast Neoplasms Benzene 3.7211921183 17162533
MESH:D001943 Breast Neoplasms decitabine 3.7218320071 19208741
MESH:D001943 Breast Neoplasms Estradiol 3.7212948864 19861407 17289903 17261762 14630087 18497071 16675129 17018787
MESH:D001943 Breast Neoplasms fulvestrant 3.7218984771
MESH:D001943 Breast Neoplasms Indomethacin 3.7217401462
MESH:D001943 Breast Neoplasms Raloxifene 3.7215775269 17893378 16837676 17049068 17440819 15758505 17242785 15572757 17595753 17261762 16912660 17952589
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 3.7220435547
MESH:D002056 Burns Indomethacin 4.6210459503
MESH:D002100 Cachexia Indomethacin 4.9211239499 15141370 16537180 15625704
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.3816111702
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.8416050911
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7316835633
MESH:D003528 Carcinoma, Adenoid Cystic marker/mechanism 16762588
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 11.2116705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 11.2116705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 11.217296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 11.213084413
MESH:D006528 Carcinoma, Hepatocellular Estradiol 11.2116924424
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 11.2116391822
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 4.6411053908
MESH:D018276 Carcinoma, Medullary Indomethacin 5.2711352223 14736730 18791128
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 6.497296757
MESH:D002292 Carcinoma, Renal Cell Indomethacin 6.4917341418
MESH:D002294 Carcinoma, Squamous Cell decitabine 4.8919215824
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 4.8912636206 15482327
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 3.9917572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3218670907 18850075 16120746
MESH:D002318 Cardiovascular Diseases Raloxifene 3.3815775269
MESH:D002386 Cataract Acetaminophen 2.5310977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 15.516135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 15.517505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 15.5120889678
MESH:D002471 Cell Transformation, Neoplastic Estradiol 15.5118566989
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.0816835633
MESH:D002764 Cholecystitis Indomethacin 5.0911181007
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 7.6419486331 9022650
MESH:D002779 Cholestasis Ethinyl Estradiol 7.6411677210 16105132 16919318 17110522 17333356 17681005 15861022
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0715668235 12621046 16354765 8697196 15340226
MESH:D003072 Cognition Disorders Raloxifene 4.5315800139
MESH:D003092 Colitis Selenium 3.6917936198
MESH:D003110 Colonic Neoplasms decitabine 3.9517616700
MESH:D003110 Colonic Neoplasms Indomethacin 3.9511260862 15786552 15637740 15936596 15963497 15625704
MESH:D015179 Colorectal Neoplasms decitabine 2.7418981723
MESH:D015179 Colorectal Neoplasms Indomethacin 2.7412606626 17054584 18059344 11197048
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9817141729 14669216
MESH:D018352 Coronavirus Infections Indomethacin 5.6417302372
MESH:D019465 Craniofacial Abnormalities Benzene 3.7915643154
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.7910048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Vitamin E 3.7919769572
MESH:D003490 Cyanosis 2,4-dinitrotoluene 10.6018551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 10.6018551238
MESH:D003865 Depressive Disorder, Major Raloxifene 4.0817474826
MESH:D003872 Dermatitis Benzene 4.6815902427
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.7212868966 2524372 11906362 14531868 8156756 18759878 8970840 11298694
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.413621924 2952479
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6517107852
MESH:D003928 Diabetic Nephropathies Estradiol 8.7519279558
MESH:D003928 Diabetic Nephropathies Raloxifene 8.7515920148 17308373 17451421
MESH:D003967 Diarrhea Indomethacin 3.717237001 7907874
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 18.3021346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 18.3018551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 18.3018289764 18692083 18648102 9328219 1440618 9653073 11289319 7440962 8291058 6482804 6679447 9022650 16192314
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 18.3018071297 16485898 12153990 11421492 11743745 17522070 19164858 16393943 12594235 19923254 12540782 16781746 18713872 14725611 10663392 16081117 11287661 12958197 19420014 2444490 17906064 16177239 10915739 19085960 11739529 15968718 11529661 17562736 14550746 12705907 14986274 11461765 15619225 19416960 19739265 19370779 16109766 12392966 10774834 16227642 11834606
MESH:D056486 Drug-Induced Liver Injury Chlorodiphenyl (54% Chlorine) 18.3017851650
MESH:D056486 Drug-Induced Liver Injury Selenium 18.3015131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 18.3020420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.0219426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6911462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 5.0618446180 12774134 16326151 16133044 17190690 18043480
MESH:D004381 Duodenal Ulcer Indomethacin 4.0517151854 16699067 17329845 17202747 11595415 11595431 17045617 17351913 11535926 11991626 10671773
MESH:C538011 Eales disease Vitamin E 4.629068938
MESH:D004487 Edema Indomethacin 11.0910653021 7907874 8985016 16100529 7990266 19703484 8273558
MESH:D004487 Edema Raloxifene 11.0915860553
MESH:D004487 Edema Tetrachlorodibenzodioxin 11.0912711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.8218230668 16714409 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.8312538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 8.8315845917
MESH:D004701 Endocrine Gland Neoplasms decitabine 5.0319294695
MESH:D016889 Endometrial Neoplasms 4-hydroxytamoxifen 7.5919148513
MESH:D016889 Endometrial Neoplasms Estradiol 7.5911473722 18566989 19148513
MESH:D004715 Endometriosis Indomethacin 8.8015652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 8.809294722 10568697
MESH:D019446 Endotoxemia Indomethacin 4.4218509659
MESH:D004751 Enteritis Indomethacin 4.6617763956 10567023 16328016
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 4.9017980183
MESH:D004802 Eosinophilia Indomethacin 3.9711298111
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 7.163581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.1620426865
MESH:D004938 Esophageal Neoplasms Indomethacin 7.1611005569
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9511564622
MESH:D005234 Fatty Liver Ethinyl Estradiol 7.5915345470
MESH:D005234 Fatty Liver Raloxifene 7.5917473493
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3711858732
MESH:D005334 Fever Indomethacin 4.0417627676 11852909 10431976
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.946705139
MESH:D005354 Fibrosarcoma Indomethacin 4.8110962813
MESH:D005355 Fibrosis Indomethacin 8.5317994277
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 8.5320067830
MESH:D005499 Folliculitis Indomethacin 5.0911298111
MESH:D005756 Gastritis Acetaminophen 10.8816983495
MESH:D005756 Gastritis Indomethacin 10.8815046732
MESH:D005909 Glioblastoma Indomethacin 3.5112870263
MESH:D005910 Glioma Indomethacin 3.1918371953 16487511
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 4.2111849393
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.957505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5110696789
MESH:D006073 Gout Indomethacin 5.2711248219
MESH:D006258 Head and Neck Neoplasms decitabine 7.8419215824
MESH:D006258 Head and Neck Neoplasms Indomethacin 7.8415482327
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.4210048152 11294989
MESH:D006330 Heart Defects, Congenital Vitamin E 6.4216080930
MESH:D006331 Heart Diseases Raloxifene 3.4711110106
MESH:D006333 Heart Failure Selenium 3.0217162251
MESH:D006402 Hematologic Diseases Benzene 4.5716183116
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2511000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 4.4915633222
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.436705139
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.5915135802
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.8116120746 15340226 12621046
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.6716490937 16863852
MESH:D006558 Herpes Genitalis Estradiol 4.9515709030
MESH:D019584 Hot Flashes Estradiol 9.7817088409
MESH:D019584 Hot Flashes Vitamin E 9.7814716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.9615340226 16959395 18606429 8697196 16354765
MESH:D006930 Hyperalgesia Acetaminophen 7.5916870215
MESH:D006930 Hyperalgesia Indomethacin 7.5912727271
MESH:D034321 Hyperamylasemia Indomethacin 5.6417883296
MESH:D006940 Hyperemia Indomethacin 4.9212524144
MESH:D006949 Hyperlipidemias Indomethacin 4.0817546600
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.8515034207
MESH:D006973 Hypertension Benzene 8.5217940673
MESH:D006973 Hypertension Raloxifene 8.5215787275 17577099
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.5218850075 18670907
MESH:D007021 Hypospadias Ethinyl Estradiol 3.7216569931 16945680
MESH:D007077 Ileal Diseases Indomethacin 4.9418306037 10574470
MESH:D007079 Ileitis Indomethacin 5.2710647630 16133968 10651667
MESH:D007235 Infant, Premature, Diseases Indomethacin 5.2916133044
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3812013081
MESH:D007248 Infertility, Male decitabine 10.9917581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 10.9917937319
MESH:D007248 Infertility, Male fulvestrant 10.9911514358
MESH:D007249 Inflammation Indomethacin 4.9612568917 3291741 7812673
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.9612200463 12878042
MESH:D007251 Influenza, Human Selenium 10.6916624496
MESH:D007251 Influenza, Human Vitamin E 10.6916624496
MESH:D007333 Insulin Resistance Estradiol 2.9116627594 16393666
MESH:D007410 Intestinal Diseases Indomethacin 4.2411713966 15610444 17329856 18236018 11855677 17994277 15831440 10210152 11686837
MESH:D019586 Intracranial Hypertension Indomethacin 5.2915241188
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.949022650 8074119
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2516580747
MESH:D007579 Jejunal Diseases Indomethacin 4.9418306037 16133968 10574470
MESH:D007674 Kidney Diseases Acetaminophen 14.0415629191 12587719
MESH:D007674 Kidney Diseases Estradiol 14.0415618244
MESH:D007674 Kidney Diseases Indomethacin 14.0417190690
MESH:D007674 Kidney Diseases Vitamin E 14.0412488133
MESH:D007676 Kidney Failure, Chronic Selenium 3.8016518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 17.1416705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 17.1416705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 17.146582329
MESH:D007680 Kidney Neoplasms Estradiol 17.1415610895
MESH:D007889 Leiomyoma Raloxifene 4.4116973256
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.8310320625 11703811 12228301
MESH:D007938 Leukemia Benzene 6.5115935818 14694614 17119257 18335105
MESH:D007938 Leukemia decitabine 6.5118980019 19235587
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 3.8615631656 10785260 16572323
MESH:D007951 Leukemia, Myeloid Benzene 9.5217506065
MESH:D007951 Leukemia, Myeloid decitabine 9.5217236224 19117987 18454857
MESH:D015470 Leukemia, Myeloid, Acute Benzene 6.2119478238
MESH:D015470 Leukemia, Myeloid, Acute decitabine 6.2118206229 19010910 19387464 18460780 17679729 18704418
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 6.2118360721
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.3818055864
MESH:D007964 Leukocytosis Indomethacin 5.2916537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.6417980183
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.6411479899
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.149327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 4.8914716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 4.8918194892
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.8912878042
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 4.8916169303
MESH:D008107 Liver Diseases Acetaminophen 1.6116610002 19014921 11587558 16611625 12587719 19460945 19784758 12969438
MESH:D017114 Liver Failure, Acute Acetaminophen 3.1617185352 16871587
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 4.267678174
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 4.2616984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 13.686135515 2876786 2876784
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 13.681399818 6587162 598648 3712494
MESH:D008114 Liver Neoplasms, Experimental Benzene 13.6812562636
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 13.6812151625
MESH:D008171 Lung Diseases Vitamin E 3.1216863852
MESH:D017563 Lung Diseases, Interstitial Benzene 4.7314698565
MESH:D008175 Lung Neoplasms Benzene 4.8112562636
MESH:D008175 Lung Neoplasms Indomethacin 4.8111497255 16537180 11053908
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.8119555203 11884234
MESH:D008175 Lung Neoplasms Vitamin E 4.8111062179
MESH:D008223 Lymphoma Benzene 7.6117119257 17584886
MESH:D008223 Lymphoma decitabine 7.6119470736
MESH:D015674 Mammary Neoplasms, Animal Benzene 4.3612562636
MESH:D008325 Mammary Neoplasms, Experimental Benzene 9.7211921183
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 9.7211408345 11807958 16891317 17203775
MESH:D008325 Mammary Neoplasms, Experimental Selenium 9.7215318939
MESH:D020149 Manganese Poisoning Estradiol 4.4019453300
MESH:D008545 Melanoma decitabine 2.2317785578 16505122
MESH:D008546 Melanoma, Experimental Acetaminophen 3.4819513568
MESH:D008654 Mesothelioma Selenium 2.7615107826
MESH:D008881 Migraine Disorders Indomethacin 3.6111903285
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.4715863610
MESH:D009062 Mouth Neoplasms Indomethacin 3.9212636206
MESH:D009101 Multiple Myeloma Benzene 11.8817119195
MESH:D009101 Multiple Myeloma decitabine 11.8818172295
MESH:D009101 Multiple Myeloma Raloxifene 11.8816497877
MESH:D009190 Myelodysplastic Syndromes decitabine 3.3319157545 16882708 18608210 19010910
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9512213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.2116810080
MESH:D009232 Myxoma Raloxifene 5.4716343187
MESH:D009336 Necrosis 2,4-dinitrotoluene 10.0618551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 10.0618551238 7678174
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 5.813581430
MESH:D009362 Neoplasm Metastasis Indomethacin 5.8111239499 11053908 16537180
MESH:D009369 Neoplasms decitabine 2.6719116145 17925555 19470736
MESH:D009374 Neoplasms, Experimental Indomethacin 4.0515625704 10663608
MESH:D009389 Neovascularization, Pathologic Estradiol 3.6517289903
MESH:D009421 Nervous System Malformations Estradiol 9.1811399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.1814600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 7.266679447
MESH:D009436 Neural Tube Defects Benzene 7.2615643154
MESH:D019636 Neurodegenerative Diseases Acetaminophen 8.1618514411
MESH:D019636 Neurodegenerative Diseases Indomethacin 8.1612349958
MESH:D007752 Obstetric Labor, Premature Indomethacin 5.096374098
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 20.9416049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 20.9416049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 20.944026338 6482804
MESH:D009784 Occupational Diseases Benzene 20.9415576619 15727169 17178637 15612468 16737584 17119257 17479406 15935809 15913788
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.943988306
MESH:D010003 Osteoarthritis Indomethacin 3.617009135
MESH:D010024 Osteoporosis Raloxifene 3.3415775268 17882678 19059307
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 4.1417823083 15579764 15758505 17893378
MESH:D010051 Ovarian Neoplasms Benzene 7.8312562636
MESH:D010051 Ovarian Neoplasms decitabine 7.8319331143 19259094
MESH:D010051 Ovarian Neoplasms Estradiol 7.8319401270
MESH:D010146 Pain Acetaminophen 6.5516870215
MESH:D010146 Pain Indomethacin 6.5517440234 17627676 3291741 13679232
MESH:D010149 Pain, Postoperative Indomethacin 4.6012538197 18702446
MESH:D010190 Pancreatic Neoplasms decitabine 2.7419294695
MESH:D010195 Pancreatitis Indomethacin 3.8415028970 17883296
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6011578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.407296757
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.6416537180
MESH:D020734 Parkinsonian Disorders Indomethacin 4.0412349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.6411903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1712520081
MESH:D010437 Peptic Ulcer Indomethacin 5.0611148446
MESH:D010518 Periodontitis Indomethacin 4.8317225004
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.396228378
MESH:D010954 Plasmacytoma Selenium 4.8115087411
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4718163543
MESH:D047928 Premature Birth Indomethacin 5.0417000239
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.1111399792 11118676 11222880 11896295
MESH:D055728 Primary Myelofibrosis decitabine 4.6417616702
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.8020887781
MESH:D011471 Prostatic Neoplasms Estradiol 2.6416740699
MESH:D011471 Prostatic Neoplasms Raloxifene 2.6416536755 16220300 15731164
MESH:D011471 Prostatic Neoplasms Vitamin E 2.6415084515
MESH:D011507 Proteinuria Indomethacin 4.0811849393
MESH:D011537 Pruritus Ethinyl Estradiol 3.2316919318 15861022
MESH:D011693 Purpura Raloxifene 5.4715770314
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7518990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.313692021
MESH:D012208 Rhabdomyosarcoma decitabine 4.3219155313
MESH:D012468 Salivary Gland Neoplasms marker/mechanism 16762588
MESH:D012640 Seizures 2,4-dinitrotoluene 5.6718551238
MESH:D012640 Seizures 2,6-dinitrotoluene 5.6718551238
MESH:D012871 Skin Diseases Vitamin E 2.4218709164
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.0016192470
MESH:D013088 Spermatocele Ethinyl Estradiol 3.8616709447
MESH:D013272 Stomach Diseases Indomethacin 4.3318209964 16280098 10192188 17160473 10215738 10486359 16113693 18545984 15472012 17638125 17207306 16184426 15038085
MESH:D013274 Stomach Neoplasms Benzene 3.5212562636
MESH:D013274 Stomach Neoplasms decitabine 3.5219037991
MESH:D013274 Stomach Neoplasms Indomethacin 3.5215609394
MESH:D013276 Stomach Ulcer Indomethacin 3.5016150113 12498302 17657623 17654042 17918041 11729361 17895592 18299717 16631530 18237397 10750652 11595431 16169175 11145282 17977527 17135157 10423059 16755016 16934674 16397915 10878458 18209962 18193104 15104355 11906479 11595415 1323529 18087811 15138204 18543354 12077510 16252198 11523592 18431645 12787963 12500499 18181030 12467913 14567935 17627676 15255614 18726076
MESH:D020521 Stroke Raloxifene 8.4716837676
MESH:D020521 Stroke Vitamin E 8.4716517955
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5411994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0715669648
MESH:D013953 Thymus Neoplasms Benzene 4.8710850423
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8212697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 11.686582329 7505956 3712494 1399818 6587162
MESH:D013964 Thyroid Neoplasms decitabine 11.6817967635
MESH:D013964 Thyroid Neoplasms Indomethacin 11.6811352223 18791128 14736730
MESH:D013978 Tibial Fractures Estradiol 13.4419048282
MESH:D013978 Tibial Fractures Raloxifene 13.4419048282
MESH:D014456 Ulcer Indomethacin 4.8110574470 17380554
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 15.4516049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 15.4516049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 15.458074119
MESH:D001749 Urinary Bladder Neoplasms decitabine 15.4517616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 15.4517572228
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 11.7010091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 11.7010091137
MESH:D014581 Urticaria Acetaminophen 2.8910982225
MESH:D014594 Uterine Neoplasms Benzene 9.2812562636
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 9.2814692618
MESH:D014604 Uveal Neoplasms decitabine 4.8317785578
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5112125929
MESH:D054556 Venous Thromboembolism Raloxifene 5.1316837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4614671159 15869587
MESH:D014839 Vomiting Indomethacin 4.6611897121
MESH:D014846 Vulvar Neoplasms Raloxifene 5.4716343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1715886252
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA36020
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


    Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved