AutismKB 2.0

Annotation Detail for SOX4


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Basic Information Top
Gene Symbol:SOX4 ( EVI16 )
Gene Full Name: SRY (sex determining region Y)-box 4
Band: 6p22.3
Quick LinksEntrez ID:6659; OMIM: 184430; Uniprot ID:SOX4_HUMAN; ENSEMBL ID: ENSG00000124766; HGNC ID: 11200
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
2101Adenoid cystic cancer
2125Bladder cancer
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of SOX4 mRNAaffects expression 21346803
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in decreased expression of SOX4 mRNAdecreases expression 12958071
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of SOX4 mRNAdecreases expression 18648102
C075773 4-phenylbutyric acid 4-phenylbutyric acid results in decreased expression of SOX4 mRNAdecreases expression 14583596
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of SOX4 proteinaffects expression 20106945
C006632 arsenic trioxide arsenic trioxide results in decreased expression of SOX4 mRNAdecreases expression 15725085
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of SOX4 mRNAincreases expression 20106945
C006780 bisphenol A bisphenol A affects the expression of SOX4 mRNAaffects expression 20170705
C006780 bisphenol A bisphenol A results in decreased expression of SOX4 mRNAdecreases expression 16474171
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of SOX4 mRNAaffects expression 17484886
C099555 CD 437 CD 437 results in decreased expression of SOX4 mRNAdecreases expression 12958071
D003345 Corticosterone Corticosterone results in decreased expression of SOX4 mRNAdecreases expression 15755911
D016572 Cyclosporine Cyclosporine results in decreased expression of SOX4 mRNAdecreases expression 20106945
D002117 Calcitriol Calcitriol results in increased expression of SOX4 mRNAincreases expression 16002434
D004317 Doxorubicin Doxorubicin results in decreased expression of SOX4 mRNAdecreases expression 17888722
D004958 Estradiol Estradiol results in decreased expression of SOX4 mRNAdecreases expression 16474171
D004958 Estradiol [Progesterone co-treated with Estradiol] results in decreased expression of SOX4 mRNAaffects cotreatment|decreases expression 17404688
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of SOX4 mRNAaffects expression 20170705
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of SOX4 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of SOX4 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SOX4 mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of SOX4 mRNAaffects expression 17351261
20170705
D005472 Fluorouracil Fluorouracil results in increased expression of SOX4 mRNAincreases expression 16510598
D005492 Folic Acid Folic Acid results in increased expression of SOX4 mRNAincreases expression 17868486
C106014 gedunin gedunin results in decreased expression of SOX4 mRNAdecreases expression 17010675
D019833 Genistein Genistein results in decreased expression of SOX4 mRNAdecreases expression 16474171
D008748 Methylcholanthrene Methylcholanthrene results in decreased expression of SOX4 mRNAdecreases expression 20713471
C030110 oxaliplatin oxaliplatin results in increased expression of SOX4 mRNAincreases expression 16510598
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of SOX4 mRNAaffects binding|decreases expression|increases activity 19710929
C006253 pirinixic acid pirinixic acid results in decreased expression of SOX4 mRNAdecreases expression 17426115
C006253 pirinixic acid pirinixic acid results in increased expression of SOX4 mRNAincreases expression 16985257
18301758
D011078 Polychlorinated Biphenyls Polychlorinated Biphenyls analog results in decreased expression of SOX4 mRNAdecreases expression 16474171
D011374 Progesterone [Progesterone co-treated with Estradiol] results in decreased expression of SOX4 mRNAaffects cotreatment|decreases expression 17404688
D011374 Progesterone Progesterone results in decreased expression of SOX4 mRNAdecreases expression 17404688
D011374 Progesterone Progesterone affects the expression of SOX4 mRNAaffects expression 17251523
D012643 Selenium [Selenium co-treated with Vitamin E] results in decreased expression of SOX4 mRNAaffects cotreatment|decreases expression 19244175
D012643 Selenium Selenium results in decreased expression of SOX4 mRNAdecreases expression 19244175
D017632 Asbestos, Serpentine Asbestos, Serpentine results in increased expression of SOX4 mRNAincreases expression 16251409
C017947 sodium arsenite sodium arsenite results in decreased expression of SOX4 mRNAdecreases expression 12727804
D013629 Tamoxifen Tamoxifen affects the expression of SOX4 mRNAaffects expression 17555576
C004648 testosterone enanthate testosterone enanthate affects the expression of SOX4 mRNAaffects expression 17440010
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of SOX4 mRNAincreases expression 20106945
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SOX4 mRNAaffects cotreatment|increases expression 17942748
C050414 tripterine tripterine results in decreased expression of SOX4 mRNAdecreases expression 17010675
C025643 vinclozolin vinclozolin affects the expression of SOX4 mRNAaffects expression 19015723
D002762 Cholecalciferol Cholecalciferol results in increased expression of SOX4 mRNAincreases expression 17170073
D014810 Vitamin E [Selenium co-treated with Vitamin E] results in decreased expression of SOX4 mRNAaffects cotreatment|decreases expression 19244175
D014810 Vitamin E Vitamin E results in decreased expression of SOX4 mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.1914745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.5015322242 14514962 11752688
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.5817505938
MESH:D058186 Acute Kidney Injury Folic Acid 4.0217003819 16316344 16595132
MESH:D055371 Acute Lung Injury pirinixic acid 2.7918653653
MESH:D000230 Adenocarcinoma arsenic trioxide 19.3511798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 19.3520464547 20127859
MESH:D000230 Adenocarcinoma Doxorubicin 19.3517418594
MESH:D000230 Adenocarcinoma Estradiol 19.3511473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 19.3514692618
MESH:D000230 Adenocarcinoma Fluorouracil 19.3517638652
MESH:D000230 Adenocarcinoma Genistein 19.3511473722
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 14.323712494
MESH:D000236 Adenoma Benzo(a)pyrene 14.326695378
MESH:D000236 Adenoma Folic Acid 14.3216963246
MESH:D000236 Adenoma Methylcholanthrene 14.3210545420 6695378
MESH:D018248 Adenoma, Liver Cell pirinixic acid 8.7216434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 8.7216835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.3415276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.5417306315 16712894
MESH:D000419 Albuminuria Doxorubicin 4.2121441931
MESH:D000544 Alzheimer Disease Folic Acid 2.9717116317
MESH:D000740 Anemia Fluorouracil 7.6716511603 17963324 15504547
MESH:D000740 Anemia Tetrachlorodibenzodioxin 7.6711748828
MESH:D001008 Anxiety Disorders vinclozolin 3.3619015723
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.7319183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.1211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.4515885639
MESH:D001195 Asbestosis Asbestos, Serpentine 5.3310751356
MESH:D050197 Atherosclerosis Methylcholanthrene 3.2411922910
MESH:D001321 Autistic Disorder Folic Acid 2.8721388746
MESH:D001327 Autoimmune Diseases Cholecalciferol 4.6816142846
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.661440618 11289319
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 13.4516206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 13.4519483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 13.4512125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.4315340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.5415746008
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.3414601052
MESH:D001862 Bone Resorption bisphenol A 3.5511985600
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.9817868700
MESH:D001930 Brain Injuries Progesterone 3.9115845082 15665606 15380490
MESH:D001932 Brain Neoplasms Doxorubicin 3.5117150277
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 9.1620146248 17474063
MESH:D001943 Breast Neoplasms bisphenol A 9.1617123778
MESH:D001943 Breast Neoplasms Calcitriol 9.1611237771
MESH:D001943 Breast Neoplasms Doxorubicin 9.1616115903 16264153 15993339 15567936 17369602 18382427 16595493 15136595 15692762 15939500 18628466 17426702 18234424 16096432 19526202 18695136 17983394 15634643 16935488 15668708 15994142 16322301 11325840 16826403
MESH:D001943 Breast Neoplasms Estradiol 9.1612948864 17018787 19861407 17261762 16675129 18497071 17289903 14630087
MESH:D001943 Breast Neoplasms Fluorouracil 9.1619217205 18357371 15136595 16557594 16595493 18608205 16110121
MESH:D001943 Breast Neoplasms Folic Acid 9.1616777985
MESH:D001943 Breast Neoplasms Genistein 9.1616873071 16541309 17200150
MESH:D001943 Breast Neoplasms Methylcholanthrene 9.1617474063
MESH:D001943 Breast Neoplasms Progesterone 9.1617614352 16175315 15562024
MESH:D001943 Breast Neoplasms Tamoxifen 9.1620135344 19487384 18351453 15565566 11161223 19084267 20005174 20390343 19059307 16202921 18984771 19410462 20859285 19115204 16273361 19288272 19066611 21138602 19244106 16873071 18821012 17261762 19103187 17049068 19155303 19221464 18425577 18629630 18997820 20544844 19289846 21152245 20065188 17893378 17242785 18815881 16818667 19142967 18855134 19189210 19200415 19189212 19011961 17440819 15668708
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 9.1620435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.0011589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.1116111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 8.7815721981 16011737 16050911 18705752 16227642 16097048 16192424 16124888 10355542 15700767 15673190 3786805
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 8.7816050911
MESH:D002276 Carcinoid Tumor Doxorubicin 11.1516051944
MESH:D002276 Carcinoid Tumor Fluorouracil 11.1516051944
MESH:D002277 Carcinoma Fluorouracil 12.3817121937
MESH:D002277 Carcinoma Methylcholanthrene 12.3810545420
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 12.3816835633
MESH:D003528 Carcinoma, Adenoid Cystic marker/mechanism 16762588
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.1619066611
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 24.6216705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 24.627296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 24.6212907637 12619106 21507988
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 24.6214691202 15553829 11135700 16217749 15073043
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 24.6218788625
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 24.6216023760 16234567 17876044 18059187
MESH:D006528 Carcinoma, Hepatocellular Estradiol 24.6216924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 24.6217088986 16332177 17971768 17045692 18930000 16799960
MESH:D006528 Carcinoma, Hepatocellular Genistein 24.6216924424
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 24.6216507464 15276417 17306315
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 24.6216924424
MESH:D002278 Carcinoma in Situ bisphenol A 4.6317123778
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.5119014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 9.797296757
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 9.791485588 16201981
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 9.7918695887
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.8112490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 13.1320419170
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 13.1311237771
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 13.136189445
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 13.1316757204 18986760 16280240 17066447
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 13.1318572023
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.3117572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.1718850075 18670907 16120746
MESH:D009202 Cardiomyopathies Doxorubicin 3.3017007740 15476868 16612575 15811867 16364871 17308081 16952015 17351982 15792986 16109756 16242529 17329180 17131338 18627295 16278810 16651473 16455267 16269455 17928571 15505089 17382496 16731534 17974986 17924179 17519947
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.8216243910 17334414
MESH:D002318 Cardiovascular Diseases Folic Acid 6.8816755160
MESH:D002318 Cardiovascular Diseases Genistein 6.8816332659
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 23.196135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 23.197505956
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 23.1912371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 23.1918566989
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 23.1916192471
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 23.1920056578 19524636
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.8716835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 17.079022650 19486331
MESH:D002779 Cholestasis Cyclosporine 17.0719486331
MESH:D002779 Cholestasis Ethinyl Estradiol 17.0717333356 16919318 15861022 17681005 17110522 16105132 11677210
MESH:D002779 Cholestasis pirinixic acid 17.0719176532
MESH:D002971 Cleft Lip Folic Acid 3.7921254359
MESH:D002972 Cleft Palate Folic Acid 5.5821254359 8946559
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.5812621046 16354765 15668235 8697196 15340226
MESH:D003092 Colitis Selenium 3.4417936198
MESH:D003110 Colonic Neoplasms Fluorouracil 5.5518772588 17725105 17172411 17287894 17018589 17169374 17016597 16510598 15001691 16340194
MESH:D003110 Colonic Neoplasms Genistein 5.5517182828
MESH:D003110 Colonic Neoplasms oxaliplatin 5.5516024531 16004971 16510598
MESH:D015179 Colorectal Neoplasms arsenic trioxide 7.8820501625
MESH:D015179 Colorectal Neoplasms Doxorubicin 7.8818259882 18802399
MESH:D015179 Colorectal Neoplasms Fluorouracil 7.8816331619 17255274 16303861 18288408 14970324 18949393 17454858 16282729 18509181 16391804 18383874 18448328 18802399 20501625 17401013 17594712 15148649 17016601 15289873 17094418 17695437 16524972
MESH:D015179 Colorectal Neoplasms Folic Acid 7.8817245555 17087956 17116713 16985020 16963246
MESH:D015179 Colorectal Neoplasms oxaliplatin 7.8817695437 18509181 18448328 17594712 17255274 17401013
MESH:D015179 Colorectal Neoplasms Polychlorinated Biphenyls 7.8815531428
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.7614669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 3.8512609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.5310525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.5315322242 10048152 20055451
MESH:D019465 Craniofacial Abnormalities Vitamin E 3.5319769572
MESH:D003456 Cryptorchidism vinclozolin 4.0014966744
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.6718551238
MESH:D007644 Darier Disease Fluorouracil 4.4416733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.7715213294
MESH:D003704 Dementia Polychlorinated Biphenyls 4.3916140633
MESH:D003711 Demyelinating Diseases Tamoxifen 4.0219031437
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.4814531868 8970840 2524372 11298694 11906362 12868966 8156756 18759878
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2618249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.172952479 3621924
MESH:D003924 Diabetes Mellitus, Type 2 Folic Acid 6.6616886840
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 6.6616647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.6617107852
MESH:D003928 Diabetic Nephropathies Estradiol 7.8619279558
MESH:D003928 Diabetic Nephropathies Tamoxifen 7.8619279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.1517187935
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 13.7518551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 13.7518692083 6679447 9022650 6482804 18289764 7440962 8291058 16192314 18648102 1440618 11289319 9328219 9653073
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 13.753786805 3732212 15027814 9327722 15998439 21278145 7179309 7440962 10092053 16227642 6884620 16177239 6623471 4309450 10915739 2869522 7120509 15968718 11566570 19336974 19085960 17522070
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 13.7517416283
MESH:D056486 Drug-Induced Liver Injury Selenium 13.7515131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 13.7520420201
MESH:D004362 Drug Toxicity Doxorubicin 7.2418602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 7.2411462148
MESH:C538011 Eales disease Vitamin E 4.349068938
MESH:D004487 Edema pirinixic acid 5.5112083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 5.5112711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.5418230668 16714409 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 19.1615138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 19.1612538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 19.1617692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 19.1619031437
MESH:D004714 Endometrial Hyperplasia Genistein 4.2316402032
MESH:D016889 Endometrial Neoplasms Doxorubicin 20.9017359293
MESH:D016889 Endometrial Neoplasms Estradiol 20.9019148513 18566989 11473722
MESH:D016889 Endometrial Neoplasms Folic Acid 20.9017301261
MESH:D016889 Endometrial Neoplasms Genistein 20.9011473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 20.9019155303 20544844 16202921 17893378
MESH:D004715 Endometriosis Progesterone 7.9116134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 7.9110568697 9294722
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.8018037988
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 9.553581430
MESH:D004938 Esophageal Neoplasms arsenic trioxide 9.5512903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 9.5516530937
MESH:D004938 Esophageal Neoplasms Fluorouracil 9.5515173087 16337965 17638652 16481741 16785472
MESH:D017889 Exfoliation Syndrome Folic Acid 5.1416504073
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.7511564622
MESH:D005234 Fatty Liver arsenic trioxide 26.6115073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 26.6119224547 15959796 16045604 12795759 17595544 16239168 61145 12631006
MESH:D005234 Fatty Liver Cyclosporine 26.6119224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 26.6115345470
MESH:D005234 Fatty Liver pirinixic acid 26.6119236843 20131406
MESH:D005234 Fatty Liver Tamoxifen 26.6114986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.0216709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.1111858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.666705139
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.1714745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 10.2619069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 10.2619069698
MESH:D005354 Fibrosarcoma Methylcholanthrene 4.5814633661 10962813
MESH:D005355 Fibrosis Carbon Tetrachloride 12.7118705752
MESH:D005355 Fibrosis Cyclosporine 12.7112639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 12.7120067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.9316904648
MESH:D005756 Gastritis Folic Acid 4.7317171786
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.5816973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.9416417039
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.3216452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.868708960
MESH:D005901 Glaucoma Folic Acid 4.7516504073
MESH:D005909 Glioblastoma Doxorubicin 6.5717150277
MESH:D005909 Glioblastoma Genistein 6.5716598420
MESH:D005910 Glioma Fluorouracil 2.7316145905
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.717505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.2310696789
MESH:D006258 Head and Neck Neoplasms Doxorubicin 7.1215692506
MESH:D006258 Head and Neck Neoplasms Fluorouracil 7.1218337622 15102660 15162350
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 14.4420471113
MESH:D006330 Heart Defects, Congenital Folic Acid 14.4416524890 17286298
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 14.4410048152 11294989
MESH:D006330 Heart Defects, Congenital Vitamin E 14.4416080930
MESH:D006331 Heart Diseases Doxorubicin 3.2416244372 18674790 17875725 17888722 18006777 16330681 16879835 16144979 16495754 16707910 14766674 16244371 12587719
MESH:D006333 Heart Failure Doxorubicin 10.5317481944
MESH:D006333 Heart Failure pirinixic acid 10.5320558911
MESH:D006333 Heart Failure Selenium 10.5317162251
MESH:D006394 Hemangiosarcoma Doxorubicin 3.5915692506
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.0715720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0211000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 8.116705139
MESH:D006505 Hepatitis Carbon Tetrachloride 8.1119110552 19900420
MESH:D006529 Hepatomegaly pirinixic acid 7.1218467677 16221962 19176532 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.1212621046 15340226 16120746
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.5716490937 16863852
MESH:D006558 Herpes Genitalis Estradiol 4.6715709030
MESH:D006679 HIV Seropositivity Folic Acid 5.1417209195
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 5.3917440010
MESH:D006689 Hodgkin Disease Doxorubicin 6.5118501091 17606976 15147373
MESH:D006689 Hodgkin Disease sodium arsenite 6.5112676792
MESH:D019584 Hot Flashes Estradiol 8.8517088409
MESH:D019584 Hot Flashes Vitamin E 8.8514716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.6816959395 15340226 16354765 18606429 8697196
MESH:D006930 Hyperalgesia oxaliplatin 4.0817418472
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.1816899240
MESH:D006943 Hyperglycemia pirinixic acid 2.8820558911
MESH:D020138 Hyperhomocysteinemia Folic Acid 4.2016395265 16755160 16433478 16865747 16397167
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.5915034207
MESH:D006973 Hypertension Cyclosporine 4.4710903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.4718670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.7415338365
MESH:D007021 Hypospadias Ethinyl Estradiol 3.4616569931 16945680
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.0615869954
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.1412013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 9.8317937319
MESH:D007248 Infertility, Male sodium arsenite 9.8315346721 12646999
MESH:D007248 Infertility, Male vinclozolin 9.8316467254
MESH:D007249 Inflammation Progesterone 7.2015869954
MESH:D007249 Inflammation Tamoxifen 7.2019457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 7.2012200463 12878042
MESH:D007251 Influenza, Human Selenium 9.7616624496
MESH:D007251 Influenza, Human Vitamin E 9.7616624496
MESH:D007333 Insulin Resistance bisphenol A 10.9716393666
MESH:D007333 Insulin Resistance Estradiol 10.9716393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 10.9716306350
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.668074119 9022650
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.0216580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.0815604871
MESH:D007674 Kidney Diseases Cyclosporine 16.868314463 10903974 18776723
MESH:D007674 Kidney Diseases Doxorubicin 16.8615369732 15699352 16775033
MESH:D007674 Kidney Diseases Estradiol 16.8615618244
MESH:D007674 Kidney Diseases sodium arsenite 16.8620008137
MESH:D007674 Kidney Diseases Vitamin E 16.8612488133
MESH:D007676 Kidney Failure, Chronic Doxorubicin 8.9316707910
MESH:D007676 Kidney Failure, Chronic Selenium 8.9316518626
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 25.3916705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 25.396582329
MESH:D007680 Kidney Neoplasms Cyclosporine 25.3912371664
MESH:D007680 Kidney Neoplasms Estradiol 25.3915610895
MESH:D007680 Kidney Neoplasms Fluorouracil 25.3916985049
MESH:D007680 Kidney Neoplasms Tamoxifen 25.3918625569
MESH:D007938 Leukemia arsenic trioxide 5.8315070760
MESH:D007938 Leukemia Genistein 5.8318980019 17468513
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.8016085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.4817077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.9516972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.1714633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.4519077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.0816467208 19850784 20471514 16968895 17050201
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 2.9811468182 17712046 16331271 19642359 15748426 9834237 12018890 15213294 16330433 17649720 19035177 16891316 16966277 19075265 17217047 12679006 16112521 12712474 19225113 16823087 15336539 11161223 17869043 17107899 15622746
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.0216882451
MESH:D007984 Leydig Cell Tumor vinclozolin 4.3816417039
MESH:D008064 Lipidoses Tamoxifen 2.9015342952 17567588
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 2.6116943688 11408273 17157831 17334410 16221502 17174718 11903743 16239168 21278145
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.979327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 12.3518420326 18205269 15931870 16116963 17823541 15057751 18376398 18705752 14512876 12898905 12666154 10355542 18054572 12632512 12389079 16192424 18472094 17631135 14748882 18418968 18006644 18339082 17869086 17766677 16033810 15362042 17714472 18481824 14724832 18210741 17481882 17640975 18395095 17708605 14716833 17565644 11481614 15123356 17900296 16027843 17922224 17721639 20821823 12546737 17698563 13678700 16638106 18395914 12445418 15959796 15925388 15730626 18277467 12632514 14620537 17557913 18472332 18279442 18251166 17805973 16136751 17525996 12609069 12586293 12649538 12445421 15370692 15338365 16015684 17976157 14716496 15893842 16097048 15650968 17761835 15818738 16248980 18187930 12741479 18263696 18429990 18156304 16011737 18166357 15996030 12958196 18412020 18317297 15052691 17944888 15673190 12667390 15876570
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 12.3516439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 12.3514716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Genistein 12.3517823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 12.3515474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 12.3518564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 12.3512878042
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 12.3516169303
MESH:D008107 Liver Diseases Carbon Tetrachloride 4.0916246199 15720792 16964402 15830285 17285989
MESH:D008107 Liver Diseases Folic Acid 4.0916877991
MESH:D017093 Liver Failure Carbon Tetrachloride 3.8215123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.3814706259 16899240
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 31.357678174
MESH:D008113 Liver Neoplasms Aflatoxin B1 31.359163691 15890375 18177683 2125692
MESH:D008113 Liver Neoplasms arsenic trioxide 31.3514682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 31.3521137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 31.3519294768
MESH:D008113 Liver Neoplasms Fluorouracil 31.3515113037 16603448 17045692 18383874
MESH:D008113 Liver Neoplasms pirinixic acid 31.3515890375 16377806 20007298
MESH:D008113 Liver Neoplasms sodium arsenite 31.3515276417 16712894
MESH:D008113 Liver Neoplasms Tamoxifen 31.3516684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 31.3516984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 34.086135515 2876786 2876784
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 34.083712494 598648 1399818 6587162
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 34.088603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 34.0820377131
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 34.0815583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 34.0816842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 34.08598648 1399818
MESH:D008114 Liver Neoplasms, Experimental Polychlorinated Biphenyls 34.081423854
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 34.0812151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.0815213294
MESH:D008171 Lung Diseases Asbestos, Serpentine 11.1217200189
MESH:D008171 Lung Diseases sodium arsenite 11.1219095001
MESH:D008171 Lung Diseases Vitamin E 11.1216863852
MESH:D008175 Lung Neoplasms Aflatoxin B1 19.3814755239
MESH:D008175 Lung Neoplasms arsenic trioxide 19.3819825857 11798837
MESH:D008175 Lung Neoplasms Asbestos, Serpentine 19.3811198217
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 19.3818816296 20464547 6695378 18520028 18569708 20064080 20135361 17053015 20869020
MESH:D008175 Lung Neoplasms Doxorubicin 19.3817418594 6189445
MESH:D008175 Lung Neoplasms Fluorouracil 19.3815246190
MESH:D008175 Lung Neoplasms Methylcholanthrene 19.3816271038 10545420 16337739 7750092 9230183 20512841 21163286 15390079 17909032 6695378 20970405 11893704 1399818
MESH:D008175 Lung Neoplasms sodium arsenite 19.3819931552 17306315 16712894 17077188 15276417
MESH:D008175 Lung Neoplasms Tamoxifen 19.3818625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 19.3811884234 19555203
MESH:D008175 Lung Neoplasms Vitamin E 19.3811062179
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.4415086387
MESH:D008180 Lupus Erythematosus, Systemic Folic Acid 3.2317718048
MESH:D008223 Lymphoma Doxorubicin 3.2116098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.5017654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.2215621674
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.4119428831
MESH:D008325 Mammary Neoplasms, Experimental Corticosterone 25.0012807724
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 25.0015458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 25.0017203775 11807958 11408345 16891317
MESH:D008325 Mammary Neoplasms, Experimental Genistein 25.0012929590 14578162
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 25.0011408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Selenium 25.0015318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 25.0016827153 14580682 19196722 11731420 19196723
MESH:D020149 Manganese Poisoning Estradiol 11.4419453300
MESH:D020149 Manganese Poisoning Tamoxifen 11.4419453300
MESH:D019767 Maxillofacial Abnormalities Folic Acid 5.3416832597
MESH:D008545 Melanoma Doxorubicin 4.7316827129
MESH:D008545 Melanoma sodium arsenite 4.7316487513 19082730
MESH:D008545 Melanoma Tamoxifen 4.7312393984 19393235
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.8315990972
MESH:D008654 Mesothelioma Doxorubicin 5.8017638057
MESH:D008654 Mesothelioma Selenium 5.8015107826
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.4316801185
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.1815792986
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 7.6316381670
MESH:D009062 Mouth Neoplasms Fluorouracil 7.6316757204 18986760
MESH:D052016 Mucositis Doxorubicin 4.4417415656
MESH:D009101 Multiple Myeloma arsenic trioxide 2.8611468182 14977855 19549372 19417148 15949261
MESH:D009135 Muscular Diseases pirinixic acid 3.1616239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.3118349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 2.9416105982 16882451
MESH:D009203 Myocardial Infarction Doxorubicin 8.5915857846 19429709
MESH:D009203 Myocardial Infarction Genistein 8.5917141266
MESH:D009203 Myocardial Infarction pirinixic acid 8.5919151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.7412213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 12.6116810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 12.6117141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 12.6116411023
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.517678174 18551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.6216624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 8.643581430
MESH:D009362 Neoplasm Metastasis Doxorubicin 8.6418259882
MESH:D009362 Neoplasm Metastasis Tamoxifen 8.6419393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4019410462
MESH:D009369 Neoplasms 4-phenylbutyric acid 13.8219116145
MESH:D009369 Neoplasms Benzo(a)pyrene 13.8211141357
MESH:D009369 Neoplasms Fluorouracil 13.8216928823 18600527 18239605
MESH:D009369 Neoplasms pirinixic acid 13.8217405874
MESH:D009369 Neoplasms sodium arsenite 13.8211559025
MESH:D009374 Neoplasms, Experimental Asbestos, Serpentine 8.3911704859
MESH:D009374 Neoplasms, Experimental sodium arsenite 8.3920056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.6419200415 19196722 19189210
MESH:D009389 Neovascularization, Pathologic Estradiol 3.3817289903
MESH:D009401 Nephrosis Doxorubicin 4.4216899518 16636307
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.0817954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 8.3118481113 19348381
MESH:D009404 Nephrotic Syndrome Doxorubicin 8.3115640375 16889571
MESH:D009421 Nervous System Malformations bisphenol A 20.6811399458 16427766
MESH:D009421 Nervous System Malformations Estradiol 20.6811399458 16427766
MESH:D009421 Nervous System Malformations Genistein 20.6816427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 20.6814600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 15.466679447
MESH:D009436 Neural Tube Defects arsenic trioxide 15.4610525206
MESH:D009436 Neural Tube Defects Folic Acid 15.4617438019
MESH:D009436 Neural Tube Defects sodium arsenite 15.4612854658
MESH:D009447 Neuroblastoma Doxorubicin 3.0815555623
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.2016436463
MESH:D009503 Neutropenia Folic Acid 4.1816322990
MESH:D009765 Obesity pirinixic acid 1.7220558911
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 7.8716049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 7.876482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.663988306
MESH:D010024 Osteoporosis Genistein 3.0419401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 3.7616169203
MESH:D012516 Osteosarcoma Doxorubicin 3.8315930896
MESH:D010049 Ovarian Diseases bisphenol A 4.6311985600
MESH:D010051 Ovarian Neoplasms arsenic trioxide 17.3019769630 16624393 12452020
MESH:D010051 Ovarian Neoplasms CD 437 17.3017474084
MESH:D010051 Ovarian Neoplasms Estradiol 17.3019401270
MESH:D010051 Ovarian Neoplasms Genistein 17.3019005980
MESH:D010051 Ovarian Neoplasms Progesterone 17.3017393432 16525653
MESH:D010051 Ovarian Neoplasms sodium arsenite 17.3017306315 15276417
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 4.9115580305
MESH:D010190 Pancreatic Neoplasms Fluorouracil 4.9116929163 19003803 15113037 16500647
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.3611578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.147296757
MESH:D010235 Paraganglioma arsenic trioxide 3.8419927285
MESH:D010300 Parkinson Disease Polychlorinated Biphenyls 3.2616702228
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.8912520081
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.116228378
MESH:D003557 Phyllodes Tumor Doxorubicin 4.8017983394
MESH:D010954 Plasmacytoma Selenium 4.5315087411
MESH:D010995 Pleural Diseases Asbestos, Serpentine 5.3510923243
MESH:D010997 Pleural Neoplasms Doxorubicin 4.8017638057
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.2218163543
MESH:D011230 Precancerous Conditions Cyclosporine 2.9312371664
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 14.2010548101
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 14.2011118676 11896295 11222880 11399792
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 14.2018042343 19015723 18220299
MESH:D011469 Prostatic Diseases vinclozolin 4.5818220299
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.4215572423
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 9.5020887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 9.5020887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 5.6419131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 5.6417292933
MESH:D011471 Prostatic Neoplasms bisphenol A 5.6416740699
MESH:D011471 Prostatic Neoplasms Calcitriol 5.6412479363 16644109 15754350 18247401 16289102
MESH:D011471 Prostatic Neoplasms Cholecalciferol 5.6417024972
MESH:D011471 Prostatic Neoplasms Doxorubicin 5.6416868541 15749863 15897917 16729912 18437689 16888761
MESH:D011471 Prostatic Neoplasms Estradiol 5.6416740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 5.6418626508 19082440
MESH:D011471 Prostatic Neoplasms Genistein 5.6415256057 15378649 16925846
MESH:D011471 Prostatic Neoplasms Polychlorinated Biphenyls 5.6415721890
MESH:D011471 Prostatic Neoplasms sodium arsenite 5.6416039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 5.6415067354
MESH:D011471 Prostatic Neoplasms Vitamin E 5.6415084515
MESH:D011472 Prostatitis vinclozolin 4.5818629315
MESH:D011537 Pruritus Ethinyl Estradiol 2.9616919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.1016882103
MESH:D011629 Puberty, Precocious bisphenol A 4.4310548101
MESH:D011658 Pulmonary Fibrosis Asbestos, Serpentine 3.6915511213 18569384
MESH:D012004 Rectal Neoplasms Fluorouracil 3.7118722050 18286688 15538739 16160472
MESH:D051437 Renal Insufficiency Doxorubicin 9.3617922066
MESH:D051437 Renal Insufficiency Folic Acid 9.3615728788
MESH:D015427 Reperfusion Injury pirinixic acid 2.2119058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.5018990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.113692021
MESH:D012468 Salivary Gland Neoplasms marker/mechanism 16762588
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.7318045962
MESH:D012509 Sarcoma Doxorubicin 3.6815625365 16767912 18313854 15675481 17203757 17710206
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 9.1616646077
MESH:D012512 Sarcoma, Ewing's Doxorubicin 9.1616326096 14601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.4417846226
MESH:D012559 Schizophrenia Folic Acid 2.8516641680
MESH:D012640 Seizures 2,6-dinitrotoluene 2.3118551238
MESH:D012871 Skin Diseases Folic Acid 4.8918709164
MESH:D012871 Skin Diseases Vitamin E 4.8918709164
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 12.1410029692 19755658
MESH:D012878 Skin Neoplasms Doxorubicin 12.1415692506
MESH:D012878 Skin Neoplasms sodium arsenite 12.1418572023 19524636
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 12.1416192470
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.2217203757 15625365 16767912
MESH:D013088 Spermatocele Ethinyl Estradiol 10.3616709447
MESH:D013088 Spermatocele Tamoxifen 10.3616709447
MESH:D013118 Spinal Cord Diseases Folic Acid 5.1416361298
MESH:D013119 Spinal Cord Injuries Progesterone 9.6916503802 15862959
MESH:D013119 Spinal Cord Injuries Tamoxifen 9.6919457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.5312854658
MESH:D013274 Stomach Neoplasms arsenic trioxide 4.4317007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 4.4320155912 2093021
MESH:D013274 Stomach Neoplasms Fluorouracil 4.4317498489 17522103 19015929 16424979 15786421 18396642 17172411 16951190 19084572 18567086
MESH:D013274 Stomach Neoplasms Folic Acid 4.4317171786
MESH:D020521 Stroke Folic Acid 7.9716517955
MESH:D020521 Stroke Vitamin E 7.9716517955
MESH:D019966 Substance-Related Disorders bisphenol A 3.6316684133 16045194
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.2911994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.8615669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.5412697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 10.463712494 7505956 6587162 6582329 1399818
MESH:D013964 Thyroid Neoplasms arsenic trioxide 10.4619014326
MESH:D013964 Thyroid Neoplasms Doxorubicin 10.4617909728 16010429
MESH:D013978 Tibial Fractures Estradiol 4.3219048282
MESH:D014062 Tongue Neoplasms Fluorouracil 3.6816280240
MESH:D016171 Torsades de Pointes arsenic trioxide 3.6115213294
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 25.9716049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 25.978074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 25.9720435036 11780464 12973940 12845720
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 25.9717053015
MESH:D001749 Urinary Bladder Neoplasms CD 437 25.9716720286
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 25.9717653716
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 25.9716452187 11723127 17306315 16712894
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 25.9717572228 8653321 16712894
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 3.9610091137
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 8.4716803524
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 8.4711813266
MESH:D014591 Uterine Diseases bisphenol A 4.6514652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.9614692618
MESH:D014605 Uveitis Cyclosporine 3.621336536
MESH:D014652 Vascular Diseases sodium arsenite 4.0717056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.2312125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.2214671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 3.8816364871 17334414 17638931 17678736
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.8915886252
MESH:D014985 Xerophthalmia Cyclosporine 4.0817120751
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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