Annotation Detail for SPAM1
Basic Information Top
| Gene Symbol: | SPAM1 ( HYA1,HYAL1,HYAL3,HYAL5,MGC26532,PH-20,PH20,SPAG15 ) |
|---|---|
| Gene Full Name: | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| Band: | 7q31 |
| Quick Links | Entrez ID:6677; OMIM: 600930; Uniprot ID:HYALP_HUMAN; ENSEMBL ID: ENSG00000106304; HGNC ID: 11217 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Diseases/Disorders| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of SPAM1 mRNA | affects expression | 17562736 |
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of SPAM1 mRNA | affects expression | 16483693 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000138 | Acidosis | Ammonium Chloride | 4.44 | 18287403 | |
| MESH:D000799 | Angioedema | Acetaminophen | 4.91 | 10982225 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.83 | 10977129 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.68 | 11743745 11287661 19923254 18071297 16485898 15968718 19370779 14725611 10663392 16177239 17562736 16781746 2444490 19085960 16081117 12705907 16393943 10915739 19164858 17906064 16109766 12153990 12540782 19739265 17522070 11461765 16227642 18713872 11529661 19416960 12594235 19420014 12392966 11421492 14550746 15619225 11739529 11834606 10774834 14986274 12958197 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 5.17 | 19426721 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.74 | 16983495 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.11 | 16870215 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.44 | 12587719 15629191 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.71 | 16610002 16611625 11587558 12969438 19014921 12587719 19784758 19460945 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.74 | 16871587 17185352 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.33 | 19513568 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.31 | 18514411 | |
| MESH:D010146 | Pain | Acetaminophen | 2.82 | 16870215 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.58 | 10982225 |
| Pathway ID | Pathway Name |
|---|---|
| KEGG:00531 | Glycosaminoglycan degradation |
| KEGG:01100 | Metabolic pathways |