AutismKB 2.0

Annotation Detail for SPARC


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Basic Information Top
Gene Symbol:SPARC ( ON )
Gene Full Name: secreted protein, acidic, cysteine-rich (osteonectin)
Band: 5q33.1
Quick LinksEntrez ID:6678; OMIM: 182120; Uniprot ID:SPRC_HUMAN; ENSEMBL ID: ENSG00000113140; HGNC ID: 11219
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1854Alveolar bone loss
1934Cancer
1987Gingival overgrowth
Desease Name
scleroderma
IMMUNE
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of SPARC mRNAdecreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of SPARC mRNAaffects expression 17562736
D019386 Alendronate Alendronate affects the expression of SPARC mRNAaffects expression 16079270
D000643 Ammonium Chloride Ammonium Chloride affects the expression of SPARC mRNAaffects expression 16483693
D016718 Arachidonic Acid Arachidonic Acid results in decreased expression of SPARC mRNAdecreases expression 16704987
D001554 Benzene [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in decreased expression of SPARC mRNAaffects cotreatment|decreases expression 17905399
C031463 beta-glycerophosphoric acid beta-glycerophosphoric acid results in decreased expression of SPARC mRNAdecreases expression 17171500
C031463 beta-glycerophosphoric acid Calcitriol promotes the reaction [beta-glycerophosphoric acid results in decreased expression of SPARC mRNA]decreases expression|increases reaction 17171500
C031463 beta-glycerophosphoric acid paricalcitol promotes the reaction [beta-glycerophosphoric acid results in decreased expression of SPARC mRNA]decreases expression|increases reaction 17171500
C095105 bexarotene bexarotene results in increased expression of SPARC mRNAincreases expression 17178900
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of SPARC mRNAdecreases expression 15336504
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of SPARC mRNAincreases expression 15963989
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of SPARC mRNAaffects expression 17484886
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of SPARC mRNAincreases expression 16239168
17056239
D003474 Curcumin Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SPARC mRNA]decreases reaction|increases expression 18200517
D003520 Cyclophosphamide Cyclophosphamide results in increased expression of SPARC mRNAincreases expression 17403535
D003520 Cyclophosphamide Cyclophosphamide results in decreased expression of SPARC mRNAdecreases expression 15331540
D016572 Cyclosporine Cyclosporine results in decreased expression of SPARC mRNAdecreases expression 20106945
C014347 decitabine [decitabine affects the methylation of SPARC promoter] which affects the expression of SPARC mRNAaffects expression|affects methylation 18458674
C014347 decitabine [decitabine affects the methylation of SPARC promoter] which affects the susceptibility to Fluorouracilaffects methylation|affects response to substance 18458674
C014347 decitabine decitabine inhibits the reaction [DNMT3A protein binds to SPARC promoter]affects binding|decreases reaction 19177197
C014347 decitabine decitabine results in increased expression of SPARC mRNAincreases expression 17397030
19177197
C014347 decitabine decitabine results in increased expression of SPARC proteinincreases expression 19177197
D004041 Dietary Fats Dietary Fats results in increased expression of SPARC mRNAincreases expression 18042831
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of SPARC mRNAincreases expression 19638242
D002117 Calcitriol Calcitriol promotes the reaction [beta-glycerophosphoric acid results in decreased expression of SPARC mRNA]decreases expression|increases reaction 17171500
D004317 Doxorubicin Doxorubicin results in increased expression of SPARC mRNAincreases expression 15870702
D000431 Ethanol Ethanol results in increased expression of SPARC mRNAincreases expression 15963989
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of SPARC mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SPARC mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of SPARC mRNAaffects expression 16079270
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of SPARC mRNAdecreases expression 17557909
D005038 Ethylnitrosourea Ethylnitrosourea results in increased expression of SPARC mRNAincreases expression 15954086
D005472 Fluorouracil [decitabine affects the methylation of SPARC promoter] which affects the susceptibility to Fluorouracilaffects methylation|affects response to substance 18458674
D005472 Fluorouracil SPARC protein results in increased susceptibility to Fluorouracilincreases response to substance 15902309
D005665 Furosemide Furosemide results in increased expression of SPARC mRNAincreases expression 16526316
C010176 halofuginone halofuginone results in increased expression of SPARC mRNAincreases expression 17180598
D007213 Indomethacin Indomethacin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SPARC mRNA]increases expression|increases reaction 17994277
D007529 Isoflavones Isoflavones affects the expression of SPARC mRNAaffects expression 16365062
D008274 Magnesium Magnesium results in increased expression of SPARC proteinincreases expression 10397942
D008713 Methimazole Methimazole results in increased expression of SPARC mRNAincreases expression 17403546
C030957 methylmercury II [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in decreased expression of SPARC mRNAaffects cotreatment|decreases expression 17905399
C030957 methylmercury II methylmercury II results in increased expression of SPARC mRNAincreases expression 17905399
D008769 Methylnitronitrosoguanidine Methylnitronitrosoguanidine results in decreased expression of SPARC mRNAdecreases expression 12634122
C406082 monomethylarsonous acid [monomethylarsonous acid affects the acetylation of HIST3H3 protein] which affects the methylation of SPARC promoteraffects acetylation|affects methylation 18448484
D017239 Paclitaxel Paclitaxel results in increased expression of SPARC mRNAincreases expression 19682730
C041786 palm oil palm oil results in increased expression of SPARC mRNAincreases expression 18042831
C084656 paricalcitol paricalcitol promotes the reaction [beta-glycerophosphoric acid results in decreased expression of SPARC mRNA]decreases expression|increases reaction 17171500
C494474 perchlorate perchlorate results in increased expression of SPARC mRNAincreases expression 17403546
D011441 Propylthiouracil Propylthiouracil results in increased expression of SPARC mRNAincreases expression 17403546
D020849 Raloxifene Raloxifene affects the expression of SPARC mRNAaffects expression 16079270
C059514 resveratrol resveratrol results in decreased expression of SPARC mRNAdecreases expression 16084059
C059514 resveratrol resveratrol results in decreased expression of SPARC proteindecreases expression 16084059
C017947 sodium arsenite [sodium arsenite affects the acetylation of HIST3H3 protein] which affects the methylation of SPARC promoteraffects acetylation|affects methylation 18448484
C017947 sodium arsenite sodium arsenite results in decreased expression of SPARC mRNAdecreases expression 18812580
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of SPARC mRNAdecreases expression 11489354
20106945
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SPARC mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of SPARC mRNAdecreases expression 11752688
D014192 Trapidil Trapidil affects the reaction [PTH protein affects the expression of SPARC mRNA]affects expression|affects reaction 18635661
D014212 Tretinoin Tretinoin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SPARC mRNA]increases expression|increases reaction 17994277
C034613 triacsin C triacsin C results in decreased expression of SPARC mRNAdecreases expression 16704987
D014241 Trichloroethylene [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in decreased expression of SPARC mRNAaffects cotreatment|decreases expression 17905399
D014302 Trinitrobenzenesulfonic Acid Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SPARC mRNA]decreases reaction|increases expression 18200517
D014302 Trinitrobenzenesulfonic Acid Indomethacin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SPARC mRNA]increases expression|increases reaction 17994277
D014302 Trinitrobenzenesulfonic Acid Tretinoin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SPARC mRNA]increases expression|increases reaction 17994277
D014302 Trinitrobenzenesulfonic Acid Trinitrobenzenesulfonic Acid results in increased expression of SPARC mRNAincreases expression 18200517
17994277
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Ethanol 6.9017676605 18926900
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 6.9014514962 11752688 15322242
MESH:D000138 Acidosis Ammonium Chloride 8.8918287403
MESH:D000138 Acidosis Ethanol 8.8911192467
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.4617505938
MESH:D058186 Acute Kidney Injury resveratrol 3.4316538975
MESH:D000230 Adenocarcinoma Doxorubicin 9.0217418594
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 9.0214692618
MESH:D000230 Adenocarcinoma Fluorouracil 9.0217638652
MESH:D000230 Adenocarcinoma Indomethacin 9.0216537180
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 22.523712494
MESH:D000236 Adenoma Diethylnitrosamine 22.526695378 10737359
MESH:D000236 Adenoma Ethylnitrosourea 22.526695378
MESH:D000236 Adenoma Indomethacin 22.5211497255
MESH:D000236 Adenoma Magnesium 22.5217823441
MESH:D000236 Adenoma resveratrol 22.5215688382
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 8.4719052882 18056438 16434500 17162532 19061943 17620307
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 8.4716835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.2115276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.4217306315 16712894
MESH:D000419 Albuminuria Doxorubicin 9.9521441931
MESH:D000419 Albuminuria Raloxifene 9.9517451421 17308373
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.8315451039 15451040
MESH:D019973 Alcohol-Related Disorders Curcumin 4.6017887948
MESH:D000505 Alopecia Isoflavones 8.3217569567
MESH:D000505 Alopecia Tretinoin 8.3215955085
MESH:D016301 Alveolar Bone Loss Indomethacin 4.8817225004
MESH:D000544 Alzheimer Disease Curcumin 8.4015590663
MESH:D000544 Alzheimer Disease Indomethacin 8.4015579461 17627676
MESH:D000544 Alzheimer Disease Raloxifene 8.4015800139
MESH:D000544 Alzheimer Disease resveratrol 8.4016162502 16183991
MESH:D000740 Anemia Fluorouracil 7.3115504547 17963324 16511603
MESH:D000740 Anemia Tetrachlorodibenzodioxin 7.3111748828
MESH:D000741 Anemia, Aplastic Benzene 4.0011369114 17661222 14761424
MESH:D000799 Angioedema Acetaminophen 3.3610982225
MESH:D000853 Anophthalmos Ethanol 4.3515513904
MESH:D001008 Anxiety Disorders Ethanol 3.6311141031
MESH:D001014 Aortic Aneurysm Indomethacin 4.4010231640
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 4.4110388637
MESH:D001161 Arteriosclerosis Cyclophosphamide 14.3815014928
MESH:D001161 Arteriosclerosis Dietary Fats 14.3815238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 14.3811256880
MESH:D018771 Arthralgia Indomethacin 4.682160914
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 10.5015885639
MESH:D001169 Arthritis, Experimental resveratrol 10.5017115116
MESH:D001169 Arthritis, Experimental Tretinoin 10.5016412693
MESH:D001172 Arthritis, Rheumatoid Curcumin 6.7016807698
MESH:D001172 Arthritis, Rheumatoid Indomethacin 6.7011248219
MESH:D001172 Arthritis, Rheumatoid Tretinoin 6.7016292516
MESH:D001249 Asthma Tretinoin 2.1916456186
MESH:D050197 Atherosclerosis Curcumin 5.9418704882
MESH:D050197 Atherosclerosis resveratrol 5.9416873680 17967414
MESH:D001321 Autistic Disorder Acetaminophen 2.3518445737
MESH:D001321 Autistic Disorder Arachidonic Acid 2.3518582451
MESH:D001321 Autistic Disorder Magnesium 2.3516846101
MESH:D001327 Autoimmune Diseases Curcumin 4.0319761891
MESH:D001471 Barrett Esophagus Tretinoin 3.9516935849
MESH:D001477 Bartter Syndrome Indomethacin 4.5210684365
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.5311289319 1440618
MESH:D001778 Blood Coagulation Disorders Propylthiouracil 12.9619483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 12.9612125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 12.9616206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.3115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.4515746008
MESH:D001855 Bone Marrow Diseases Benzene 4.7416183116
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.2114601052
MESH:D001859 Bone Neoplasms Paclitaxel 4.1315867366
MESH:D001927 Brain Diseases Ethylnitrosourea 4.4714991843
MESH:D001929 Brain Edema Indomethacin 4.5411481608
MESH:D001930 Brain Injuries Raloxifene 4.0116580743
MESH:D002545 Brain Ischemia Curcumin 14.3516770732
MESH:D002545 Brain Ischemia Indomethacin 14.3512524144
MESH:D002545 Brain Ischemia resveratrol 14.3517600658
MESH:D001932 Brain Neoplasms Curcumin 12.3917596214
MESH:D001932 Brain Neoplasms Doxorubicin 12.3917150277
MESH:D001932 Brain Neoplasms Ethylnitrosourea 12.3916651633 15144691 16436596 18412241 16357521
MESH:D001943 Breast Neoplasms Benzene 16.5517162533 11921183
MESH:D001943 Breast Neoplasms bexarotene 16.5516818667 16344269
MESH:D001943 Breast Neoplasms Calcitriol 16.5511237771
MESH:D001943 Breast Neoplasms Curcumin 16.5519250217 18593918 16243823 18462866
MESH:D001943 Breast Neoplasms Cyclophosphamide 16.5517020986 18323546 15093573 12006526 15136595 18234424 16978400 11325840 17388661
MESH:D001943 Breast Neoplasms decitabine 16.5519208741 18320071
MESH:D001943 Breast Neoplasms Dietary Fats 16.5520435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 16.5517474063
MESH:D001943 Breast Neoplasms Doxorubicin 16.5519526202 16322301 18234424 18695136 18628466 16826403 15668708 15939500 16096432 16595493 16264153 17983394 15994142 15136595 16935488 15692762 11325840 15993339 15567936 16115903 18382427 17426702 15634643 17369602
MESH:D001943 Breast Neoplasms Fluorouracil 16.5518357371 19217205 15136595 18608205 16110121 16557594 16595493
MESH:D001943 Breast Neoplasms Indomethacin 16.5517401462
MESH:D001943 Breast Neoplasms Paclitaxel 16.5518323546 16115903 16273361 18234424 16244791 11325840 15136595 18223236
MESH:D001943 Breast Neoplasms Raloxifene 16.5517440819 15758505 17952589 15572757 17595753 17893378 16837676 17049068 17261762 15775269 16912660 17242785
MESH:D001943 Breast Neoplasms resveratrol 16.5517651959 16393696 17534123
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 16.5520435547
MESH:D001943 Breast Neoplasms Tretinoin 16.5516443354 16873071 16166294
MESH:D001943 Breast Neoplasms Trichloroethylene 16.5515986119
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.1116813970
MESH:D002056 Burns Ethanol 9.8316374292
MESH:D002056 Burns Indomethacin 9.8310459503
MESH:D002100 Cachexia Indomethacin 4.5315141370 16537180 15625704 11239499
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.323786805 16227642 16011737 15700767 16192424 16097048 10355542 15673190 16050911 16124888 18705752 15721981
MESH:D002276 Carcinoid Tumor Doxorubicin 10.7316051944
MESH:D002276 Carcinoid Tumor Fluorouracil 10.7316051944
MESH:D002277 Carcinoma Curcumin 11.7818593918
MESH:D002277 Carcinoma Fluorouracil 11.7817121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 11.7816835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.6716168501
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 30.087296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 30.083084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 30.0818788625
MESH:D006528 Carcinoma, Hepatocellular Cyclophosphamide 30.0819701751
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 30.0816935385 20432363 18788625 16807293 20101231 19519916 19383236 19418558 16328049 18393292 3084413 19171122 17055752 16681979 20514400 20084675 19107877 18691550 20512989 3581430 16569478 19335982 19919837 19394651 10672840 18056438 20214788 19701751 16878318 20524982 20727157 18978308 16698587 16779866 19208518 18971187 18494052 18210153 17162532 18785209 16540662 19539802 16830150 20007298 16502159 17761372 19052882 11831363 10737359 17428255 19822196 17173139 16288022 21159647 20935162 18506893 18665156 17138121 17978847
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 30.0818059187 17876044 16023760 16234567
MESH:D006528 Carcinoma, Hepatocellular Ethanol 30.0818788625 15763234 15289165
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 30.0816332177 17088986 17971768 16799960 18930000 17045692
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 30.0816391822
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 30.0816313753
MESH:D006528 Carcinoma, Hepatocellular resveratrol 30.0819321006 16227395
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 30.0816507464 17306315 15276417
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 30.081917145
MESH:D018827 Carcinoma, Lewis Lung Cyclophosphamide 16.3416152834
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 16.3411053908
MESH:D018827 Carcinoma, Lewis Lung resveratrol 16.3416675471
MESH:D018276 Carcinoma, Medullary Indomethacin 4.8714736730 11352223 18791128
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 5.2316247446
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 5.2318414057
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 17.657296757
MESH:D002292 Carcinoma, Renal Cell Cyclophosphamide 17.6516201981
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 17.651485588 16201981
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 17.6518695887
MESH:D002292 Carcinoma, Renal Cell Indomethacin 17.6517341418
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 27.0511237771
MESH:D002294 Carcinoma, Squamous Cell Curcumin 27.0518462866
MESH:D002294 Carcinoma, Squamous Cell decitabine 27.0519215824
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 27.056189445
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 27.0518986760 16757204 17066447 16280240
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 27.0512636206 15482327
MESH:D002294 Carcinoma, Squamous Cell resveratrol 27.0516227395
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 27.0518572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 27.0516096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 3.6617572228
MESH:D006332 Cardiomegaly Ethanol 5.9219332462
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 5.9216120746 18850075 18670907
MESH:D009202 Cardiomyopathies Doxorubicin 3.2117382496 17519947 18627295 17308081 16278810 15476868 17974986 16612575 17928571 16364871 15811867 15505089 17351982 17329180 17924179 16109756 16952015 17131338 17007740 16731534 15792986 16651473 16242529 16455267 16269455
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.7716243910 17334414
MESH:D002318 Cardiovascular Diseases Isoflavones 10.4217689850
MESH:D002318 Cardiovascular Diseases Raloxifene 10.4215775269
MESH:D002318 Cardiovascular Diseases resveratrol 10.4215458977
MESH:D002386 Cataract Acetaminophen 6.2510977129
MESH:D002386 Cataract Tretinoin 6.2517460283
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 26.687505956
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 26.6812371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 26.6821159647 2727394 17174075 7505956
MESH:D002471 Cell Transformation, Neoplastic Ethylnitrosourea 26.6816003739
MESH:D002471 Cell Transformation, Neoplastic Methylnitronitrosoguanidine 26.682727394
MESH:D002471 Cell Transformation, Neoplastic monomethylarsonous acid 26.6819716837
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 26.6819524636 20056578
MESH:D016543 Central Nervous System Neoplasms Ethylnitrosourea 5.5017160924
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.1116129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 7.9919052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 7.9916835633
MESH:D002764 Cholecystitis Indomethacin 4.6811181007
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 11.3219486331 9022650
MESH:D002779 Cholestasis Cyclosporine 11.3219486331
MESH:D002779 Cholestasis Ethinyl Estradiol 11.3216919318 11677210 17681005 16105132 17333356 17110522 15861022
MESH:D002822 Choriocarcinoma Tretinoin 4.6716461808
MESH:D002971 Cleft Lip Ethanol 3.3215513904
MESH:D002972 Cleft Palate Ethanol 8.5615513904
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 8.5616354765 15340226 12621046 8697196 15668235
MESH:D002972 Cleft Palate Tretinoin 8.569407595
MESH:D003072 Cognition Disorders Raloxifene 4.1515800139
MESH:D003092 Colitis Curcumin 19.0816782535 16804969 18200517
MESH:D003092 Colitis resveratrol 19.0816474422
MESH:D003092 Colitis Tretinoin 19.0817035595
MESH:D003092 Colitis Trinitrobenzenesulfonic Acid 19.0811698051 16474422 18200517 18023891 17936198 16804969 17991707 16782535 16867261
MESH:D003093 Colitis, Ulcerative Trinitrobenzenesulfonic Acid 3.2717276891
MESH:D003103 Coloboma Curcumin 4.1218809619
MESH:D003110 Colonic Neoplasms marker/mechanism 17397030
MESH:D003110 Colonic Neoplasms Curcumin 9.9116340194 19359593
MESH:D003110 Colonic Neoplasms decitabine 9.9117616700
MESH:D003110 Colonic Neoplasms Fluorouracil 9.9117725105 17169374 16510598 17172411 18772588 16340194 15001691 17016597 17287894 17018589
MESH:D003110 Colonic Neoplasms Indomethacin 9.9115936596 11260862 15625704 15963497 15786552 15637740
MESH:D003110 Colonic Neoplasms resveratrol 9.9116338953
MESH:D003111 Colonic Polyps Magnesium 5.6017823441
MESH:D015179 Colorectal Neoplasms marker/mechanism 18458674
MESH:D015179 Colorectal Neoplasms decitabine 11.6818981723
MESH:D015179 Colorectal Neoplasms Doxorubicin 11.6818802399 18259882
MESH:D015179 Colorectal Neoplasms Fluorouracil 11.6818802399 15289873 20501625 17094418 17695437 16391804 16282729 16331619 18383874 18949393 16524972 18288408 18448328 16303861 14970324 15148649 18509181 17454858 17594712 17255274 17016601 17401013
MESH:D015179 Colorectal Neoplasms Indomethacin 11.6811197048 12606626 17054584 18059344
MESH:D015179 Colorectal Neoplasms Isoflavones 11.6817116718
MESH:D015179 Colorectal Neoplasms Magnesium 11.6817823441
MESH:D015179 Colorectal Neoplasms Paclitaxel 11.6818802399
MESH:D015179 Colorectal Neoplasms resveratrol 11.6816550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.6617141729 14669216
MESH:D016510 Corneal Neovascularization Curcumin 4.4318497527
MESH:D003327 Coronary Disease resveratrol 3.4416507316
MESH:D018352 Coronavirus Infections Indomethacin 5.2317302372
MESH:D019465 Craniofacial Abnormalities Benzene 4.9015643154
MESH:D019465 Craniofacial Abnormalities Ethanol 4.9015451039 15513904 15451040 11873399 11198716 19302082 10194807
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 4.9015322242 20055451 10048152
MESH:D019465 Craniofacial Abnormalities Tretinoin 4.909125849 9664655 16925845 17551590 9142499 14991402 9211117 10589399 9224671 8800419
MESH:D003556 Cystitis Cyclophosphamide 4.5018483878 15643279 18093676 10700343 16989017 12161096 16413132 16651033 17979934 18710439 11948286 18372110 10498854 12913760 18433785 18295254 16614059 17010015 12388444 15276878
MESH:D007644 Darier Disease Fluorouracil 4.3116733453
MESH:D003865 Depressive Disorder, Major Raloxifene 3.7617474826
MESH:D003872 Dermatitis Benzene 4.3015902427
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.3714531868 11298694 11906362 18759878 12868966 8970840 8156756 2524372
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.052952479 3621924
MESH:D002658 Developmental Disabilities Magnesium 4.5816846101
MESH:D003921 Diabetes Mellitus, Experimental Cyclophosphamide 7.3911751995 10990075 15331540
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 7.3916873680
MESH:D003922 Diabetes Mellitus, Type 1 Cyclophosphamide 3.0618772604
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 6.3118403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 6.3120387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.3117107852
MESH:D003928 Diabetic Nephropathies Curcumin 12.8518204486
MESH:D003928 Diabetic Nephropathies Raloxifene 12.8517308373 17451421 15920148
MESH:D003928 Diabetic Nephropathies resveratrol 12.8516286809
MESH:D003967 Diarrhea Indomethacin 3.357237001 7907874
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 19.3018289764 7440962 1440618 9653073 8291058 6482804 18648102 9328219 11289319 18692083 9022650 6679447 16192314
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 19.3012153990 19085960 11529661 15968718 18071297 16109766 11743745 10915739 14550746 16081117 10663392 11461765 11287661 19370779 17906064 2444490 11739529 11421492 18713872 12594235 12705907 11834606 12540782 19416960 16393943 10774834 19164858 16227642 12958197 19420014 12392966 14725611 16781746 17562736 16485898 14986274 17522070 19923254 19739265 16177239 15619225
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 19.3015998439 10915739 19336974 7179309 16177239 16227642 11566570 2869522 6623471 9327722 7440962 6884620 3786805 10092053 3732212 17522070 19085960 21278145 7120509 15968718 4309450 15027814
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 19.3019107877
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 19.3017416283
MESH:D056486 Drug-Induced Liver Injury Ethanol 19.3011566570
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 19.3020420201
MESH:D056486 Drug-Induced Liver Injury Trichloroethylene 19.307120509
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.6119426721
MESH:D004362 Drug Toxicity Doxorubicin 6.9218602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 6.9211462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 4.6718446180 16326151 18043480 17190690 16133044 12774134
MESH:D004381 Duodenal Ulcer Curcumin 7.9217351913
MESH:D004381 Duodenal Ulcer Indomethacin 7.9211991626 11595415 10671773 17329845 17045617 17151854 16699067 17351913 17202747 11535926 11595431
MESH:D050171 Dyslipidemias Dietary Fats 3.1118367378
MESH:D004417 Dyspnea Furosemide 4.4616935035
MESH:D004476 Ectodermal Dysplasia Ethylnitrosourea 5.5018357618
MESH:D004487 Edema Arachidonic Acid 21.589831321 11698051 15177302 7990266 9599246 16716910
MESH:D004487 Edema Furosemide 21.5811834646
MESH:D004487 Edema Indomethacin 21.5816100529 10653021 7907874 7990266 8273558 19703484 8985016
MESH:D004487 Edema Raloxifene 21.5815860553
MESH:D004487 Edema resveratrol 21.588985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 21.5811000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.3318230668 16714409 15322242
MESH:D004489 Edema, Cardiac Tretinoin 10.3318230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 18.2515138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 18.2512538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 18.2515845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 18.2517872969
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.6319294695
MESH:D016889 Endometrial Neoplasms Doxorubicin 6.5217359293
MESH:D016889 Endometrial Neoplasms Tretinoin 6.5216569247
MESH:D004715 Endometriosis Indomethacin 7.7015652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 7.7010568697 9294722
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.6718037988
MESH:D019446 Endotoxemia Indomethacin 4.0318509659
MESH:D004751 Enteritis Indomethacin 4.2610567023 17763956 16328016
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 10.8217980183
MESH:D020345 Enterocolitis, Necrotizing resveratrol 10.8217923197
MESH:D004802 Eosinophilia Cyclophosphamide 7.7011006010
MESH:D004802 Eosinophilia Indomethacin 7.7011298111
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.6316302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 12.283581430
MESH:D004938 Esophageal Neoplasms Ethanol 12.2816704527
MESH:D004938 Esophageal Neoplasms Fluorouracil 12.2816785472 17638652 16481741 15173087 16337965
MESH:D004938 Esophageal Neoplasms Indomethacin 12.2811005569
MESH:D004938 Esophageal Neoplasms Paclitaxel 12.2816481741
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.6411564622
MESH:D005124 Eye Abnormalities Tretinoin 7.6416938888 9664655
MESH:D005234 Fatty Liver Carbon Tetrachloride 35.8717595544 12795759 16239168 16045604 61145 12631006 19224547 15959796
MESH:D005234 Fatty Liver Curcumin 35.8719297423
MESH:D005234 Fatty Liver Cyclosporine 35.8719224547
MESH:D005234 Fatty Liver Dietary Fats 35.8719004024 19551842 17967931 18296743
MESH:D005234 Fatty Liver Diethylnitrosamine 35.8721071580 20387270
MESH:D005234 Fatty Liver Ethanol 35.8719236843 16409862 18620774
MESH:D005234 Fatty Liver Ethinyl Estradiol 35.8715345470
MESH:D005234 Fatty Liver Raloxifene 35.8717473493
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.1817920746
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.8216946407 15451040 15513904 10194807
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.9911858732
MESH:D005334 Fever Arachidonic Acid 8.2211852909
MESH:D005334 Fever Indomethacin 8.2217627676 10431976 11852909
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.536705139
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.1119069698
MESH:D005354 Fibrosarcoma Indomethacin 4.4210962813
MESH:D005355 Fibrosis Carbon Tetrachloride 40.4318705752
MESH:D005355 Fibrosis Curcumin 40.4318705752
MESH:D005355 Fibrosis Cyclosporine 40.4312168785 12639820
MESH:D005355 Fibrosis Dietary Fats 40.4318296743
MESH:D005355 Fibrosis Indomethacin 40.4317994277
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 40.4320067830
MESH:D005355 Fibrosis Tretinoin 40.4317994277
MESH:D005355 Fibrosis Trinitrobenzenesulfonic Acid 40.4317994277
MESH:D005499 Folliculitis Indomethacin 4.6811298111
MESH:D005756 Gastritis Acetaminophen 16.2416983495
MESH:D005756 Gastritis Ethanol 16.2415046732
MESH:D005756 Gastritis Indomethacin 16.2415046732
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.2318462866
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.2016452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.748708960
MESH:D005909 Glioblastoma Curcumin 18.8917596214
MESH:D005909 Glioblastoma Doxorubicin 18.8917150277
MESH:D005909 Glioblastoma Ethylnitrosourea 18.8916436596
MESH:D005909 Glioblastoma Indomethacin 18.8912870263
MESH:D005909 Glioblastoma Tretinoin 18.8917312396
MESH:D005910 Glioma Ethylnitrosourea 8.8418412241 16651633 16357521
MESH:D005910 Glioma Fluorouracil 8.8416145905
MESH:D005910 Glioma Indomethacin 8.8418371953 16487511
MESH:D018316 Gliosarcoma Cyclophosphamide 5.0411389073
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 3.9011849393
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 10.017505956
MESH:D006042 Goiter perchlorate 10.0118801409
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.1110696789
MESH:D006073 Gout Indomethacin 4.8711248219
MESH:D006086 Graft vs Host Disease Cyclophosphamide 4.5711014644 16376943 15172196
MESH:D006258 Head and Neck Neoplasms Curcumin 25.8818829502 18462866
MESH:D006258 Head and Neck Neoplasms decitabine 25.8819215824
MESH:D006258 Head and Neck Neoplasms Doxorubicin 25.8815692506
MESH:D006258 Head and Neck Neoplasms Fluorouracil 25.8815162350 15102660 18337622
MESH:D006258 Head and Neck Neoplasms Indomethacin 25.8815482327
MESH:D006258 Head and Neck Neoplasms Tretinoin 25.8816096774
MESH:D034381 Hearing Loss Furosemide 4.4317868369
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.6716084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 5.6510048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 5.6514991402 9664655
MESH:D006331 Heart Diseases Doxorubicin 6.7216707910 16495754 18674790 12587719 18006777 16244372 16879835 16330681 17875725 16144979 16244371 14766674 17888722
MESH:D006331 Heart Diseases Raloxifene 6.7211110106
MESH:D006333 Heart Failure Doxorubicin 6.6017481944
MESH:D006333 Heart Failure Furosemide 6.6016011733 12660669 16845234
MESH:D006394 Hemangiosarcoma Doxorubicin 3.4815692506
MESH:D006402 Hematologic Diseases Benzene 4.2116183116
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.9415720958
MESH:D006467 Hemophilia A Cyclophosphamide 4.8211918545
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.9111000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 4.1415633222
MESH:D006504 Hepatic Veno-Occlusive Disease Cyclophosphamide 5.0514986274
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 7.736705139
MESH:D006505 Hepatitis Carbon Tetrachloride 7.7319900420 19110552
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.2315135802
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.4416120746 15340226 12621046
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.5717701891
MESH:D006561 Herpes Simplex resveratrol 3.7116876885
MESH:D006689 Hodgkin Disease Cyclophosphamide 10.0616135485 17606976
MESH:D006689 Hodgkin Disease Doxorubicin 10.0615147373 18501091 17606976
MESH:D006689 Hodgkin Disease sodium arsenite 10.0612676792
MESH:D019584 Hot Flashes Isoflavones 4.5014716179 17290160
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.5618606429 16354765 15340226 16959395 8697196
MESH:D006930 Hyperalgesia Acetaminophen 20.5216870215
MESH:D006930 Hyperalgesia Alendronate 20.5216769263
MESH:D006930 Hyperalgesia Ethanol 20.5218783367
MESH:D006930 Hyperalgesia Indomethacin 20.5212727271
MESH:D006930 Hyperalgesia Tretinoin 20.5216870215
MESH:D034321 Hyperamylasemia Indomethacin 5.2317883296
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.0516899240
MESH:D006934 Hypercalcemia Furosemide 4.6517652376
MESH:D053565 Hypercalciuria Furosemide 5.1817652376
MESH:D006937 Hypercholesterolemia Curcumin 12.9118704882
MESH:D006937 Hypercholesterolemia Dietary Fats 12.9121332399
MESH:D006937 Hypercholesterolemia resveratrol 12.9117188708
MESH:D006940 Hyperemia Indomethacin 4.5312524144
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.1016778211
MESH:D006949 Hyperlipidemias Dietary Fats 12.9821332399
MESH:D006949 Hyperlipidemias Indomethacin 12.9817546600
MESH:D006949 Hyperlipidemias resveratrol 12.9816873680
MESH:D006962 Hyperparathyroidism, Secondary Furosemide 5.3915086907
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 9.5915034207
MESH:D006965 Hyperplasia halofuginone 9.5911874485
MESH:D006973 Hypertension Benzene 10.7117940673
MESH:D006973 Hypertension Cyclosporine 10.7110903974
MESH:D006973 Hypertension Raloxifene 10.7115787275 17577099
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 10.7118670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.6215338365
MESH:D046110 Hypertension, Pregnancy-Induced Furosemide 4.8216612254
MESH:D006980 Hyperthyroidism Methimazole 5.1614678291
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 3.8917488730
MESH:C537153 Hypomagnesemia primary Furosemide 5.1811041285
MESH:D007019 Hypoproteinemia Furosemide 5.3916096441
MESH:D007021 Hypospadias Ethinyl Estradiol 3.3416569931 16945680
MESH:D007022 Hypotension Furosemide 4.1811041285
MESH:D007024 Hypotension, Orthostatic Furosemide 4.9315811171
MESH:D007037 Hypothyroidism Methimazole 10.4018031379
MESH:D007037 Hypothyroidism Propylthiouracil 10.4018031379 8137927
MESH:D007077 Ileal Diseases Indomethacin 4.5410574470 18306037
MESH:D007079 Ileitis Indomethacin 4.8716133968 10651667 10647630
MESH:D007154 Immune System Diseases Cyclophosphamide 4.8516076520
MESH:D007235 Infant, Premature, Diseases Indomethacin 4.8816133044
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.1817600658
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.0212013081
MESH:D007248 Infertility, Male Cyclophosphamide 13.4016517039 7193160
MESH:D007248 Infertility, Male decitabine 13.4017581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 13.4017937319
MESH:D007248 Infertility, Male sodium arsenite 13.4012646999 15346721
MESH:D007249 Inflammation Arachidonic Acid 20.1815177302 9831321 17371808
MESH:D007249 Inflammation Curcumin 20.1817151092 16956363 18403477
MESH:D007249 Inflammation Dietary Fats 20.1820412841
MESH:D007249 Inflammation Diethylnitrosamine 20.1818785209
MESH:D007249 Inflammation Indomethacin 20.1812568917 3291741 7812673
MESH:D007249 Inflammation resveratrol 20.1816366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 20.1812878042 12200463
MESH:D015212 Inflammatory Bowel Diseases Curcumin 5.9918200517 18596194
MESH:D015212 Inflammatory Bowel Diseases Trinitrobenzenesulfonic Acid 5.9918200517
MESH:D007251 Influenza, Human resveratrol 4.0616624496
MESH:D007333 Insulin Resistance Dietary Fats 2.7918457598 11836018
MESH:D007410 Intestinal Diseases Indomethacin 13.8518236018 11713966 17994277 11686837 10210152 11855677 15610444 15831440 17329856
MESH:D007410 Intestinal Diseases Tretinoin 13.8517994277
MESH:D007410 Intestinal Diseases Trinitrobenzenesulfonic Acid 13.8517994277
MESH:D007414 Intestinal Neoplasms Curcumin 3.8110783313
MESH:D019586 Intracranial Hypertension Indomethacin 4.8815241188
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.539022650 8074119
MESH:D007569 Jaw Abnormalities Ethanol 14.7215513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 14.7216580747
MESH:D007569 Jaw Abnormalities Tretinoin 14.7217551590 15992940
MESH:D007579 Jejunal Diseases Indomethacin 4.5416133968 18306037 10574470
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.9515604871
MESH:D007674 Kidney Diseases Acetaminophen 20.1412587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 20.148314463 10903974 18776723
MESH:D007674 Kidney Diseases Doxorubicin 20.1415699352 15369732 16775033
MESH:D007674 Kidney Diseases Furosemide 20.1411041285
MESH:D007674 Kidney Diseases Indomethacin 20.1417190690
MESH:D007674 Kidney Diseases sodium arsenite 20.1420008137
MESH:D007676 Kidney Failure, Chronic Doxorubicin 3.7316707910
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 14.636582329
MESH:D007680 Kidney Neoplasms Cyclosporine 14.6312371664
MESH:D007680 Kidney Neoplasms Ethylnitrosourea 14.6317379185
MESH:D007680 Kidney Neoplasms Fluorouracil 14.6316985049
MESH:D007859 Learning Disorders Ethanol 3.7515451040
MESH:D007889 Leiomyoma Curcumin 9.6918555241
MESH:D007889 Leiomyoma Raloxifene 9.6916973256
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.5210320625 11703811 12228301
MESH:D007938 Leukemia Benzene 17.0214694614 18335105 17119257 15935818
MESH:D007938 Leukemia Curcumin 17.0218462866
MESH:D007938 Leukemia Cyclophosphamide 17.0210602166
MESH:D007938 Leukemia decitabine 17.0219235587 18980019
MESH:D007938 Leukemia Tretinoin 17.0217143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.6716085563
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Cyclophosphamide 3.2817008537 17296974 17802794 18172266 18587576 17658394
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 3.7816106398
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Cyclophosphamide 7.6110373061
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 7.6116572323 10785260 15631656
MESH:D007951 Leukemia, Myeloid Benzene 13.6117506065
MESH:D007951 Leukemia, Myeloid decitabine 13.6118454857 19117987 17236224
MESH:D007951 Leukemia, Myeloid Tretinoin 13.6116932348 19285840 16482212
MESH:D015470 Leukemia, Myeloid, Acute marker/mechanism 18206229
MESH:D015470 Leukemia, Myeloid, Acute Benzene 7.9019478238
MESH:D015470 Leukemia, Myeloid, Acute decitabine 7.9018206229 17679729 19010910 18704418 19387464 18460780
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 7.9018360721
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 7.9016294345 19850784 17596541
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 4.9818055864
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 6.7016087638
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 6.7017361223 16140955 17339181 19225113 16766008 16823087 19075265 16935935 17712046 12679006 16788101 17294898 17368321 17649720 17107899 19029980 9834237 17301526 16891316 17506722 16331271 17217047 19035177 15748426 19642359
MESH:D015458 Leukemia, T-Cell Curcumin 4.3116106398
MESH:D007964 Leukocytosis Indomethacin 4.8816537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.2317980183
MESH:D007970 Leukopenia Cyclophosphamide 4.4910052129 11830472
MESH:D017880 Limb Deformities, Congenital Ethanol 7.1617676605
MESH:D017880 Limb Deformities, Congenital Tretinoin 7.169224671
MESH:D008080 Liposarcoma Paclitaxel 4.3817353645
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.2311479899
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 17.8217334410 11408273 16239168 11903743 16221502 16943688 21278145 17157831 17174718
MESH:D008103 Liver Cirrhosis Dietary Fats 17.8218296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 17.8220032147 19638242 18665156 18407596 18522880
MESH:D008103 Liver Cirrhosis Ethanol 17.8215289165
MESH:D008103 Liver Cirrhosis halofuginone 17.8217180598
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.6218295389
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.899327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental therapeutic 18615449
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 11.9016027843 18420326 18429990 18395095 16248980 12389079 15673190 15876570 18395914 16192424 15818738 12632512 18205269 15123356 18251166 17631135 12546737 17944888 18376398 18317297 12632514 18472332 12741479 16116963 18054572 18705752 18279442 15057751 12445418 15959796 12898905 18472094 16015684 14748882 18210741 17698563 17805973 15931870 17557913 17565644 15730626 15052691 17708605 18277467 15996030 17869086 12586293 16638106 17714472 18263696 18412020 18481824 15338365 14512876 17761835 18166357 17721639 17640975 10355542 17823541 12445421 14716496 12666154 18156304 17525996 15362042 12649538 18339082 18187930 13678700 17766677 15370692 12958196 17922224 16033810 12667390 14716833 12609069 16136751 17900296 17976157 16011737 11481614 20821823 18006644 17481882 18418968 15925388 14620537 15650968 16097048 15893842 14724832
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 11.9017355460 18705752 18006644
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 11.9016595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 11.9018166357
MESH:D008106 Liver Cirrhosis, Experimental halofuginone 11.9014739098 12175628 11172339 18458672 16489207
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 11.9018194892
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 11.9012878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 11.9016248980 18397230
MESH:D008107 Liver Diseases Acetaminophen 8.1611587558 16611625 16610002 12969438 12587719 19014921 19784758 19460945
MESH:D008107 Liver Diseases Carbon Tetrachloride 8.1615720792 16964402 16246199 15830285 17285989
MESH:D008107 Liver Diseases Curcumin 8.1616956363
MESH:D008107 Liver Diseases Diethylnitrosamine 8.1617034775
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.1917347304 17207112
MESH:D017093 Liver Failure Carbon Tetrachloride 3.7015123358
MESH:D017114 Liver Failure, Acute Acetaminophen 8.0317185352 16871587
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 8.0316899240 14706259
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 15.3419294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 15.3419499222 19294768 19090486 19254457 20405173 18754104 19642983 20583210 20492335 18648771 10737359 20101389 19551842 18644402 2862719 15885732 21047994 19255062 2422723 19850985 19073162 18977376 21167192 15175105 19812893 19996281 20452335 20434301 12112319 21278145 19426721 20501860 9163691 21071580 19833225 19256749 20118626 18978307 19427195 16942905 19690152 19638242 12771043 20137499
MESH:D008113 Liver Neoplasms Fluorouracil 15.3417045692 18383874 16603448 15113037
MESH:D008113 Liver Neoplasms resveratrol 15.3419321006 19073162 20405173 19812893
MESH:D008113 Liver Neoplasms sodium arsenite 15.3415276417 16712894
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 15.3416984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 23.55598648 1399818 3712494 6587162
MESH:D008114 Liver Neoplasms, Experimental Benzene 23.5512562636
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 23.5515583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 23.5517854601 18093689 19539802 2563599 19009564 16842330 18775883 18164116 16267830 19519916 21159647 19004024 18282651 9362446 19126423 17942915 18079962 3124819 18253720 18544905 17174075 18308698
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 23.5516842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 23.5512151625
MESH:D008114 Liver Neoplasms, Experimental Trichloroethylene 23.557955063
MESH:D008171 Lung Diseases sodium arsenite 2.8519095001
MESH:D017563 Lung Diseases, Interstitial Benzene 4.3214698565
MESH:D008175 Lung Neoplasms Benzene 16.2712562636
MESH:D008175 Lung Neoplasms bexarotene 16.2717849452
MESH:D008175 Lung Neoplasms Curcumin 16.2716243823 18462866 19359593
MESH:D008175 Lung Neoplasms Diethylnitrosamine 16.2721163286 20970405 20512841 6695378
MESH:D008175 Lung Neoplasms Doxorubicin 16.276189445 17418594
MESH:D008175 Lung Neoplasms Ethylnitrosourea 16.2716271038 16019985 17703301 6695378
MESH:D008175 Lung Neoplasms Fluorouracil 16.2715246190
MESH:D008175 Lung Neoplasms Indomethacin 16.2711053908 11497255 16537180
MESH:D008175 Lung Neoplasms sodium arsenite 16.2717306315 16712894 17077188 19931552 15276417
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 16.2711884234 19555203
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.3115086387
MESH:D008223 Lymphoma Benzene 24.7517584886 17119257
MESH:D008223 Lymphoma Curcumin 24.7518462866
MESH:D008223 Lymphoma Cyclophosphamide 24.7512854902
MESH:D008223 Lymphoma decitabine 24.7519470736
MESH:D008223 Lymphoma Doxorubicin 24.7516098063
MESH:D008223 Lymphoma Ethylnitrosourea 24.7515790496
MESH:D016393 Lymphoma, B-Cell Cyclophosphamide 9.0116675587
MESH:D016393 Lymphoma, B-Cell resveratrol 9.0117088997
MESH:D008228 Lymphoma, Non-Hodgkin Cyclophosphamide 17.5311911406
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 17.5317654614
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 17.5314749477
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 17.5314749477
MESH:D016399 Lymphoma, T-Cell Curcumin 16.7916173963
MESH:D016399 Lymphoma, T-Cell Doxorubicin 16.7915621674
MESH:D016399 Lymphoma, T-Cell Ethylnitrosourea 16.7915375218
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 4.6811161223
MESH:D008275 Magnesium Deficiency Magnesium 5.9717823441
MESH:D015674 Mammary Neoplasms, Animal Benzene 8.6712562636
MESH:D015674 Mammary Neoplasms, Animal resveratrol 8.6715688416
MESH:D008325 Mammary Neoplasms, Experimental Benzene 15.5211921183
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 15.5219196723 15591091 19196722
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 15.5215458769
MESH:D008325 Mammary Neoplasms, Experimental Ethylnitrosourea 15.5210767621 10838139 18041768
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 15.528985016 11606380
MESH:D008527 Medulloblastoma Tretinoin 2.5817453147
MESH:D008545 Melanoma Curcumin 13.7718462866 17885582
MESH:D008545 Melanoma decitabine 13.7716505122 17785578
MESH:D008545 Melanoma Doxorubicin 13.7716827129
MESH:D008545 Melanoma Paclitaxel 13.7712040289 16342250 12025231
MESH:D008545 Melanoma resveratrol 13.7717992120
MESH:D008545 Melanoma sodium arsenite 13.7719082730 16487513
MESH:D008545 Melanoma Tretinoin 13.7716752155
MESH:D008546 Melanoma, Experimental Acetaminophen 9.2919513568
MESH:D008546 Melanoma, Experimental Cyclophosphamide 9.2916388313
MESH:D008569 Memory Disorders Curcumin 8.2517263510
MESH:D008569 Memory Disorders Ethanol 8.2515451040 18411066
MESH:D008579 Meningioma Ethylnitrosourea 5.5017943659
MESH:D008591 Meningomyelocele Tretinoin 3.9616940565
MESH:D008654 Mesothelioma Doxorubicin 2.8517638057
MESH:D008659 Metabolic Diseases resveratrol 3.9517112576
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.3016801185
MESH:D053842 Microsatellite Instability Methylnitronitrosoguanidine 5.4117671175
MESH:D008881 Migraine Disorders Indomethacin 7.1511903285
MESH:D008881 Migraine Disorders Magnesium 7.1518803445
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.0715792986
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.0715863610
MESH:D009062 Mouth Neoplasms Fluorouracil 7.6016757204 18986760
MESH:D009062 Mouth Neoplasms Indomethacin 7.6012636206
MESH:D052016 Mucositis Doxorubicin 4.3117415656
MESH:D009101 Multiple Myeloma marker/mechanism 18172295
MESH:D009101 Multiple Myeloma Benzene 23.7917119195
MESH:D009101 Multiple Myeloma Curcumin 23.7919372569
MESH:D009101 Multiple Myeloma decitabine 23.7918172295
MESH:D009101 Multiple Myeloma Paclitaxel 23.7914749477
MESH:D009101 Multiple Myeloma Raloxifene 23.7916497877
MESH:D009101 Multiple Myeloma resveratrol 23.7917935668 17164350 16267019 16490592 14749477 17049120
MESH:D009134 Muscular Atrophy, Spinal Curcumin 10.8317962980
MESH:D009134 Muscular Atrophy, Spinal resveratrol 10.8317962980
MESH:D009190 Myelodysplastic Syndromes decitabine 6.5319157545 18608210 19010910 16882708
MESH:D009190 Myelodysplastic Syndromes Tretinoin 6.5317596541
MESH:D009203 Myocardial Infarction Doxorubicin 5.3119429709 15857846
MESH:D009203 Myocardial Infarction resveratrol 5.3116456233 17125593 17188708 17015251 16317513 16525036
MESH:D017202 Myocardial Ischemia resveratrol 7.7517125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 7.7512213967
MESH:D009205 Myocarditis resveratrol 4.2817322642
MESH:D009232 Myxoma Raloxifene 5.0716343187
MESH:D009361 Neoplasm Invasiveness Curcumin 3.9218495463
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 15.703581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 15.709029167 3581430
MESH:D009362 Neoplasm Metastasis Doxorubicin 15.7018259882
MESH:D009362 Neoplasm Metastasis Indomethacin 15.7016537180 11239499 11053908
MESH:D009362 Neoplasm Metastasis Paclitaxel 15.7015867366
MESH:D009369 Neoplasms Cyclophosphamide 16.5118854779
MESH:D009369 Neoplasms decitabine 16.5117925555 19116145 19470736
MESH:D009369 Neoplasms Fluorouracil 16.5116928823 18600527 18239605
MESH:D009369 Neoplasms sodium arsenite 16.5111559025
MESH:D009369 Neoplasms Tretinoin 16.5116594593 16946489
MESH:D009369 Neoplasms Trichloroethylene 16.5111911487
MESH:D009374 Neoplasms, Experimental Ethylnitrosourea 18.0016707424
MESH:D009374 Neoplasms, Experimental Indomethacin 18.0015625704 10663608
MESH:D009374 Neoplasms, Experimental resveratrol 18.008985016
MESH:D009374 Neoplasms, Experimental sodium arsenite 18.0020056578
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 9.5219196722
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 9.5212497104
MESH:D009397 Nephrocalcinosis Furosemide 5.3915086907
MESH:D009401 Nephrosis Doxorubicin 4.3016636307 16899518
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.9517954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 7.9619348381 18481113
MESH:D009404 Nephrotic Syndrome Doxorubicin 7.9616889571 15640375
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 8.0114600291
MESH:D009421 Nervous System Malformations Tretinoin 8.019125849
MESH:D009423 Nervous System Neoplasms Curcumin 5.1418462866
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 14.726679447
MESH:D009436 Neural Tube Defects Benzene 14.7215643154
MESH:D009436 Neural Tube Defects sodium arsenite 14.7212854658
MESH:D009436 Neural Tube Defects Tretinoin 14.729142499
MESH:D009442 Neurilemmoma Ethylnitrosourea 4.9417160924 16003739 16651423
MESH:D009447 Neuroblastoma Cyclophosphamide 6.3416115947 8761367 15176712
MESH:D009447 Neuroblastoma Doxorubicin 6.3415555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 16.9118514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 16.9120387270
MESH:D019636 Neurodegenerative Diseases Indomethacin 16.9112349958
MESH:D019636 Neurodegenerative Diseases resveratrol 16.9117652729
MESH:D017599 Neuroectodermal Tumors Cyclophosphamide 4.418761367 12837982
MESH:D020078 Neurogenic Inflammation resveratrol 3.9617929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.6320387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.1116436463
MESH:D009503 Neutropenia Cyclophosphamide 3.898291058
MESH:D053206 Nocturnal Enuresis Furosemide 5.3917945291
MESH:D009765 Obesity Curcumin 4.3119297423
MESH:D009765 Obesity Dietary Fats 4.3120518802 20132043 21332399 11836018 18457598 17217161 16723640 18674790 19632207
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.686374098
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 7.794026338 6482804
MESH:D009784 Occupational Diseases Benzene 7.7917479406 17119257 15913788 15727169 16737584 15612468 15576619 15935809 17178637
MESH:D009837 Oligodendroglioma Ethylnitrosourea 5.5017160924
MESH:D009845 Oligospermia Cyclophosphamide 4.2416517039
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.533988306
MESH:D010003 Osteoarthritis Indomethacin 3.377009135
MESH:D010013 Osteogenesis Imperfecta marker/mechanism 1793673
MESH:D010014 Osteolysis Paclitaxel 4.5015867366
MESH:D010024 Osteoporosis Alendronate 14.5317882678
MESH:D010024 Osteoporosis Curcumin 14.5318719352
MESH:D010024 Osteoporosis Isoflavones 14.5316562857
MESH:D010024 Osteoporosis Raloxifene 14.5319059307 15775268 17882678
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 8.7515758505 15579764 17823083 17893378
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 8.7517513867
MESH:D012516 Osteosarcoma Doxorubicin 3.7315930896
MESH:D010051 Ovarian Neoplasms marker/mechanism 19177197
MESH:D010051 Ovarian Neoplasms Benzene 16.6212562636
MESH:D010051 Ovarian Neoplasms Curcumin 16.6218462866 19020741
MESH:D010051 Ovarian Neoplasms decitabine 16.6219331143 19259094
MESH:D010051 Ovarian Neoplasms Paclitaxel 16.6211161223
MESH:D010051 Ovarian Neoplasms sodium arsenite 16.6217306315 15276417
MESH:D010051 Ovarian Neoplasms Tretinoin 16.6216936753
MESH:D010146 Pain Acetaminophen 12.9816870215
MESH:D010146 Pain Cyclophosphamide 12.9812161096 18093676
MESH:D010146 Pain Indomethacin 12.9817627676 17440234 3291741 13679232
MESH:D010146 Pain Tretinoin 12.9816870215
MESH:D010149 Pain, Postoperative Indomethacin 4.1912538197 18702446
MESH:D010190 Pancreatic Neoplasms Curcumin 21.9019401701 19196508 17440100
MESH:D010190 Pancreatic Neoplasms Cyclophosphamide 21.9011332152
MESH:D010190 Pancreatic Neoplasms decitabine 21.9019294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 21.9016540662
MESH:D010190 Pancreatic Neoplasms Ethanol 21.9012384795
MESH:D010190 Pancreatic Neoplasms Fluorouracil 21.9019003803 16929163 16500647 15113037
MESH:D010190 Pancreatic Neoplasms Tretinoin 21.9015976015
MESH:D010195 Pancreatitis Indomethacin 7.3917883296 15028970
MESH:D010195 Pancreatitis Trinitrobenzenesulfonic Acid 7.3917698068
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.2511578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.027296757
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.2316537180
MESH:D020734 Parkinsonian Disorders Indomethacin 3.7112349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.2311903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.7612520081
MESH:D010437 Peptic Ulcer Indomethacin 4.6711148446
MESH:D010518 Periodontitis Indomethacin 4.4317225004
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 3.986228378
MESH:D003557 Phyllodes Tumor Doxorubicin 4.6717983394
MESH:D010997 Pleural Neoplasms Doxorubicin 4.6717638057
MESH:D011141 Polyuria Furosemide 5.1817945291
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.1118163543
MESH:D011230 Precancerous Conditions Cyclosporine 7.6112371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 7.612563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Cyclophosphamide 3.5321297632
MESH:D047928 Premature Birth Indomethacin 4.6617000239
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 8.0116679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 8.0111222880 11896295 11399792 11118676
MESH:D055728 Primary Myelofibrosis decitabine 4.2617616702
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.3015572423
MESH:D011471 Prostatic Neoplasms Calcitriol 3.2812479363 16289102 15754350 18247401 16644109
MESH:D011471 Prostatic Neoplasms Curcumin 3.2818226269 15129424 18769126 18156803 11398177 12497104 10851300
MESH:D011471 Prostatic Neoplasms Cyclophosphamide 3.2817136230
MESH:D011471 Prostatic Neoplasms Doxorubicin 3.2815897917 15749863 16729912 18437689 16888761 16868541
MESH:D011471 Prostatic Neoplasms Fluorouracil 3.2819082440 18626508
MESH:D011471 Prostatic Neoplasms Isoflavones 3.2816365062 17571952 17219775 17374662
MESH:D011471 Prostatic Neoplasms Paclitaxel 3.2817172428 17136230 16356831 16729912
MESH:D011471 Prostatic Neoplasms Raloxifene 3.2816220300 16536755 15731164
MESH:D011471 Prostatic Neoplasms resveratrol 3.2817675339 17636462 17718901 17804756 16731767 15767336
MESH:D011471 Prostatic Neoplasms sodium arsenite 3.2816039940
MESH:D011507 Proteinuria Indomethacin 7.8811849393
MESH:D011507 Proteinuria Tretinoin 7.8816636307
MESH:D011537 Pruritus Ethinyl Estradiol 2.8416919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.0516882103
MESH:D011625 Pterygium Tretinoin 4.3216723453
MESH:D011656 Pulmonary Emphysema Curcumin 4.1119168576
MESH:D011658 Pulmonary Fibrosis Cyclophosphamide 3.0916636934
MESH:D011693 Purpura Raloxifene 5.0715770314
MESH:D012004 Rectal Neoplasms Fluorouracil 3.6116160472 18722050 18286688 15538739
MESH:D051437 Renal Insufficiency Doxorubicin 3.7617922066
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.1016325855
MESH:D015427 Reperfusion Injury Furosemide 6.3016526316
MESH:D015427 Reperfusion Injury resveratrol 6.3016317513 16314181 17520802 17058453 15827377
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 8.0710666014 18379247
MESH:D012128 Respiratory Distress Syndrome, Adult Furosemide 8.0716096441 15912074 12394941
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.3818990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.023692021
MESH:D012208 Rhabdomyosarcoma decitabine 9.4919155313
MESH:D012208 Rhabdomyosarcoma Tretinoin 9.4916283617 16116481
MESH:D012509 Sarcoma Curcumin 8.2018462866
MESH:D012509 Sarcoma Doxorubicin 8.2016767912 17203757 15675481 17710206 15625365 18313854
MESH:D012512 Sarcoma, Ewing's Doxorubicin 3.7914601052 16326096
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.3117846226
MESH:D012595 Scleroderma, Systemic Cyclophosphamide 4.3816636934
MESH:D012640 Seizures Ethanol 2.869754883
MESH:D018805 Sepsis Curcumin 3.6918389075
MESH:D012871 Skin Diseases halofuginone 5.1811874485
MESH:D012871 Skin Diseases monomethylarsonous acid 5.1817431481
MESH:D012878 Skin Neoplasms Doxorubicin 19.3215692506
MESH:D012878 Skin Neoplasms resveratrol 19.328985016 15837718
MESH:D012878 Skin Neoplasms sodium arsenite 19.3218572023 19524636
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 19.328532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 19.3216192470
MESH:D012878 Skin Neoplasms Tretinoin 19.3216467112
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.1016767912 17203757 15625365
MESH:D013088 Spermatocele Ethinyl Estradiol 3.4616709447
OMIM:102530 SPERMATOGENIC FAILURE 6 Cyclophosphamide 5.0416517039
MESH:D016135 Spinal Dysraphism sodium arsenite 3.4312854658
MESH:D013272 Stomach Diseases Indomethacin 3.9417207306 18545984 16280098 16184426 17638125 10215738 16113693 10192188 17160473 18209964 15472012 10486359 15038085
MESH:D013274 Stomach Neoplasms Benzene 13.7312562636
MESH:D013274 Stomach Neoplasms decitabine 13.7319037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 13.7318456281
MESH:D013274 Stomach Neoplasms Ethanol 13.7318456281
MESH:D013274 Stomach Neoplasms Fluorouracil 13.7316424979 16951190 17172411 19015929 15786421 18396642 17498489 18567086 19084572 17522103
MESH:D013274 Stomach Neoplasms Furosemide 13.7317052386
MESH:D013274 Stomach Neoplasms Indomethacin 13.7315609394
MESH:D013274 Stomach Neoplasms Paclitaxel 13.7318506536 18396642
MESH:D013274 Stomach Neoplasms Tretinoin 13.7317261132
MESH:D013276 Stomach Ulcer Curcumin 9.7619188055 16631530
MESH:D013276 Stomach Ulcer Ethanol 9.7616755016 9562338 17918041 11906479 9211565 17189318
MESH:D013276 Stomach Ulcer Indomethacin 9.7612467913 17895592 15255614 10423059 18431645 15138204 18087811 11595431 18193104 16631530 18543354 16934674 16150113 16397915 17627676 16169175 10750652 12077510 18299717 16755016 15104355 10878458 11523592 17977527 14567935 1323529 18209962 11906479 18181030 17918041 11595415 18726076 17654042 12787963 16252198 12498302 18237397 17135157 11729361 12500499 11145282 17657623
MESH:D020521 Stroke Raloxifene 3.4516837676
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.0616321402
MESH:D013375 Substance Withdrawal Syndrome Ethanol 3.849754883
MESH:D015173 Supratentorial Neoplasms Cyclophosphamide 4.5812837982
MESH:D024801 Tauopathies Paclitaxel 4.3416930453
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.1811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.7515669648
MESH:D013953 Thymus Neoplasms Benzene 10.6110850423
MESH:D013953 Thymus Neoplasms Ethylnitrosourea 10.6115790496
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.4212697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 28.206582329 3712494 6587162 7505956 1399818
MESH:D013964 Thyroid Neoplasms decitabine 28.2017967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 28.207505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 28.2016010429 17909728
MESH:D013964 Thyroid Neoplasms Indomethacin 28.2018791128 14736730 11352223
MESH:D013964 Thyroid Neoplasms Propylthiouracil 28.2015710170
MESH:D013964 Thyroid Neoplasms Tretinoin 28.2016026305 17045167
MESH:D013978 Tibial Fractures Raloxifene 4.7219048282
MESH:D014062 Tongue Neoplasms Fluorouracil 14.1916280240
MESH:D014062 Tongue Neoplasms resveratrol 14.1916227395
MESH:D014062 Tongue Neoplasms Tretinoin 14.1916051514
MESH:D014376 Tuberculosis Tretinoin 2.9216040207
MESH:D014456 Ulcer Indomethacin 4.4217380554 10574470
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 24.878074119
MESH:D001749 Urinary Bladder Neoplasms Curcumin 24.8718593936
MESH:D001749 Urinary Bladder Neoplasms Cyclophosphamide 24.8714692829
MESH:D001749 Urinary Bladder Neoplasms decitabine 24.8717616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 24.8717653716
MESH:D001749 Urinary Bladder Neoplasms monomethylarsonous acid 24.8720375083
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 24.8717572228
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 24.8716452187 11723127 17306315 16712894
MESH:D014565 Urogenital Neoplasms Curcumin 4.7918462866
MESH:D014581 Urticaria Acetaminophen 2.5410982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 19.2416803524
MESH:D002583 Uterine Cervical Neoplasms resveratrol 19.2417473185
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 19.2411813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 19.2416129372
MESH:D014594 Uterine Neoplasms Benzene 13.5012562636
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 13.5014692618
MESH:D014594 Uterine Neoplasms resveratrol 13.5017044934
MESH:D014604 Uveal Neoplasms decitabine 11.2117785578
MESH:D014604 Uveal Neoplasms Tretinoin 11.2116752155
MESH:D014605 Uveitis Cyclosporine 3.501336536
MESH:D014652 Vascular Diseases sodium arsenite 3.9517056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.1112125929
MESH:D054556 Venous Thromboembolism Raloxifene 4.7216837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.1114671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 8.8017334414 16364871 17638931 17678736
MESH:D018487 Ventricular Dysfunction, Left resveratrol 8.8017488730
MESH:D014820 Vitiligo Tretinoin 3.6016761959
MESH:D014839 Vomiting Indomethacin 4.2611897121
MESH:D014846 Vulvar Neoplasms Raloxifene 5.0716343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.7615886252
MESH:D015430 Weight Gain Dietary Fats 3.3416723640
MESH:D009396 Wilms Tumor Tretinoin 3.5616287080
MESH:D014985 Xerophthalmia Cyclosporine 3.9517120751
Pathway ID Pathway Name
REACT:604 Hemostasis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA36055
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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