AutismKB 2.0

Annotation Detail for SPRR2A


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Basic Information Top
Gene Symbol:SPRR2A ( - )
Gene Full Name: small proline-rich protein 2A
Band: 1q21.3
Quick LinksEntrez ID:6700; OMIM: 182267; Uniprot ID:SPR2A_HUMAN; ENSEMBL ID: ENSG00000241794; HGNC ID: 11261
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C105260 4-tert-octylphenol 4-tert-octylphenol results in increased expression of SPRR2A mRNAincreases expression 20438831
C432165 anthra(1,9-cd)pyrazol-6(2H)-one anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Ozone results in increased expression of SPRR2A mRNA]decreases reaction|increases expression 17460151
C006632 arsenic trioxide [Tetradecanoylphorbol Acetate co-treated with arsenic trioxide] results in increased expression of SPRR2A mRNAaffects cotreatment|increases expression 18922899
C015001 arsenite arsenite results in increased expression of SPRR2A mRNAincreases expression 18991936
C006780 bisphenol A bisphenol A results in increased expression of SPRR2A mRNAincreases expression 20438831
C006780 bisphenol A fulvestrant inhibits the reaction [bisphenol A results in increased expression of SPRR2A mRNA]decreases reaction|increases expression 20438831
C006780 bisphenol A Progesterone inhibits the reaction [bisphenol A results in increased expression of SPRR2A mRNA]decreases reaction|increases expression 20438831
C014347 decitabine decitabine results in increased expression of SPRR2A mRNAincreases expression 16367923
C014347 decitabine decitabine results in increased expression of SPRR2A mRNAincreases expression 15251184
C014347 decitabine [Tetrachlorodibenzodioxin co-treated with decitabine] results in increased expression of SPRR2A mRNAaffects cotreatment|increases expression 15251184
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of SPRR2A mRNAincreases expression 16636312
15289156
15591538
15171707
D004958 Estradiol Estradiol affects the expression of SPRR2A mRNAaffects expression 15598610
D004958 Estradiol Estradiol results in increased expression of SPRR2A mRNAincreases expression 15289156
20438831
D004958 Estradiol fulvestrant inhibits the reaction [Estradiol results in increased expression of SPRR2A mRNA]decreases reaction|increases expression 20438831
D004958 Estradiol Progesterone inhibits the reaction [Estradiol results in increased expression of SPRR2A mRNA]decreases reaction|increases expression 20438831
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of SPRR2A mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of SPRR2A mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SPRR2A mRNAaffects cotreatment|increases expression 17942748
D005480 Flurbiprofen Flurbiprofen results in increased expression of SPRR2A mRNAincreases expression 16949054
C070081 fulvestrant fulvestrant inhibits the reaction [bisphenol A results in increased expression of SPRR2A mRNA]decreases reaction|increases expression 20438831
C070081 fulvestrant fulvestrant inhibits the reaction [Estradiol results in increased expression of SPRR2A mRNA]decreases reaction|increases expression 20438831
D019833 Genistein Genistein results in increased expression of SPRR2A mRNAincreases expression 15289156
C029424 hydrazine hydrazine results in decreased expression of SPRR2A mRNAdecreases expression 15282401
D010126 Ozone anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Ozone results in increased expression of SPRR2A mRNA]decreases reaction|increases expression 17460151
C006253 pirinixic acid pirinixic acid results in decreased expression of SPRR2A mRNAdecreases expression 17426115
D011374 Progesterone Progesterone affects the expression of SPRR2A mRNAaffects expression 17251523
D011374 Progesterone Progesterone inhibits the reaction [bisphenol A results in increased expression of SPRR2A mRNA]decreases reaction|increases expression 20438831
D011374 Progesterone Progesterone inhibits the reaction [Estradiol results in increased expression of SPRR2A mRNA]decreases reaction|increases expression 20438831
D017632 Asbestos, Serpentine Asbestos, Serpentine results in increased expression of SPRR2A mRNAincreases expression 16251409
C009277 sodium arsenate sodium arsenate results in increased expression of SPRR2A mRNAincreases expression 12727804
C017947 sodium arsenite sodium arsenite results in increased expression of SPRR2A mRNAincreases expression 17350061
D013629 Tamoxifen Tamoxifen affects the expression of SPRR2A mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with decitabine] results in increased expression of SPRR2A mRNAaffects cotreatment|increases expression 15251184
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SPRR2A mRNAaffects cotreatment|increases expression 17942748
D013755 Tetradecanoylphorbol Acetate [Tetradecanoylphorbol Acetate co-treated with arsenic trioxide] results in increased expression of SPRR2A mRNAaffects cotreatment|increases expression 18922899
D014028 Tobacco Smoke Pollution Tobacco Smoke Pollution results in decreased expression of SPRR2A mRNAdecreases expression 18087596
C015559 trimellitic anhydride trimellitic anhydride results in decreased expression of SPRR2A mRNAdecreases expression 16141432
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.3814745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.6815322242 11752688 14514962
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.7717505938
MESH:D055371 Acute Lung Injury pirinixic acid 2.9618653653
MESH:D000230 Adenocarcinoma arsenic trioxide 9.8111798837 19825857
MESH:D000230 Adenocarcinoma Estradiol 9.8111473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 9.8114692618
MESH:D000230 Adenocarcinoma Genistein 9.8111473722
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Tobacco Smoke Pollution 5.3615814487
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.3316434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.3316835633
MESH:D011125 Adenomatous Polyposis Coli Flurbiprofen 4.9110680582
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.5315276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.7316712894 17306315
MESH:D000544 Alzheimer Disease Ozone 2.4015513908
MESH:D000686 Amyloidosis Diethylstilbestrol 4.3115469931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8011748828
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.2911256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.5615885639
MESH:D001172 Arthritis, Rheumatoid Ozone 4.8715570426
MESH:D001172 Arthritis, Rheumatoid Tobacco Smoke Pollution 4.8719898480
MESH:D001195 Asbestosis Asbestos, Serpentine 5.5010751356
MESH:D001249 Asthma Ozone 5.3616373670 17854713
MESH:D001249 Asthma trimellitic anhydride 5.3616141432
MESH:D001284 Atrophy fulvestrant 4.6811514358
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 14.3716206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 14.3719483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 14.3712125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6515746008
MESH:D001862 Bone Resorption bisphenol A 3.7111985600
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.1717868700
MESH:D001930 Brain Injuries Progesterone 4.0915665606 15845082 15380490
MESH:D001943 Breast Neoplasms bisphenol A 5.6717123778
MESH:D001943 Breast Neoplasms decitabine 5.6718320071 19208741
MESH:D001943 Breast Neoplasms Diethylstilbestrol 5.6715324884 17129689
MESH:D001943 Breast Neoplasms Estradiol 5.6714630087 17261762 16675129 17289903 17018787 19861407 18497071 12948864
MESH:D001943 Breast Neoplasms fulvestrant 5.6718984771
MESH:D001943 Breast Neoplasms Genistein 5.6716541309 17200150 16873071
MESH:D001943 Breast Neoplasms Progesterone 5.6717614352 15562024 16175315
MESH:D001943 Breast Neoplasms Tamoxifen 5.6719289846 20859285 18351453 19115204 18815881 16873071 17893378 19059307 18629630 18984771 20065188 19189210 17242785 20005174 20135344 19189212 19142967 20390343 16818667 19103187 19011961 19221464 19155303 15668708 18821012 16273361 18425577 21152245 18855134 19200415 19066611 17440819 16202921 20544844 11161223 19410462 18997820 19288272 19244106 19487384 17261762 17049068 15565566 19084267 21138602
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 5.6720435547
MESH:D016535 Bronchial Hyperreactivity Ozone 3.5416777450 18417511 15516495 14754758 17626835 19059883 18315731
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.1711589617
MESH:D002100 Cachexia Ozone 4.5716183385
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.2916111702
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6616835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.3419066611
MESH:D006528 Carcinoma, Hepatocellular anthra(1,9-cd)pyrazol-6(2H)-one 13.6619418558
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 13.6615553829 16217749 11135700 14691202 15073043
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 13.6616924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Estradiol 13.6616924424
MESH:D006528 Carcinoma, Hepatocellular Genistein 13.6616924424
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 13.6615276417 17306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 13.6616924424
MESH:D002278 Carcinoma in Situ bisphenol A 4.8217123778
MESH:D002289 Carcinoma, Non-Small-Cell Lung Tobacco Smoke Pollution 3.3711212258
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.7019014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.9712490120
MESH:D002294 Carcinoma, Squamous Cell decitabine 10.4719215824
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 10.4718572023
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 10.4718922899
MESH:D002294 Carcinoma, Squamous Cell Tobacco Smoke Pollution 10.4711212258
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.4617572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.2718670907 18850075 16120746
MESH:D002318 Cardiovascular Diseases Genistein 3.1916332659
MESH:D002471 Cell Transformation, Neoplastic Estradiol 6.3518566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 6.3520056578 19524636
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.0216835633
MESH:D002779 Cholestasis Ethinyl Estradiol 7.3217333356 17110522 16919318 16105132 11677210 15861022 17681005
MESH:D002779 Cholestasis pirinixic acid 7.3219176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.038697196 15668235 16354765 12621046 15340226
MESH:D003110 Colonic Neoplasms arsenite 5.7415037631
MESH:D003110 Colonic Neoplasms decitabine 5.7417616700
MESH:D003110 Colonic Neoplasms Genistein 5.7417182828
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.5420501625
MESH:D015179 Colorectal Neoplasms decitabine 2.5418981723
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9117141729 14669216
MESH:D023903 Coronary Restenosis arsenic trioxide 4.0212609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.7710525206
MESH:D019465 Craniofacial Abnormalities sodium arsenate 3.7710525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.7710048152 20055451 15322242
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.3912952375 16002989
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.9315213294
MESH:D003711 Demyelinating Diseases Tamoxifen 4.1919031437
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3518249437
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 4.1916647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.1917107852
MESH:D003928 Diabetic Nephropathies Estradiol 8.3619279558
MESH:D003928 Diabetic Nephropathies Tamoxifen 8.3619279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.3217187935
MESH:D056486 Drug-Induced Liver Injury sodium arsenate 3.9118186108
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.9120420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6311462148
MESH:D004487 Edema pirinixic acid 10.5712083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 10.5711000095 12711302
MESH:D004487 Edema Tetradecanoylphorbol Acetate 10.5711698051 9599246 8113982 8273558 16716910 7812673 15177302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.7318230668 16714409 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 14.3612538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 14.3617692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 14.3619031437
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.9419294695
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 11.3216402032
MESH:D004714 Endometrial Hyperplasia Genistein 11.3216402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 16.8815700306 16804899
MESH:D016889 Endometrial Neoplasms Estradiol 16.8811473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Genistein 16.8811473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 16.8816202921 19155303 20544844 17893378
MESH:D004715 Endometriosis Progesterone 8.4316134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 8.4310568697 9294722
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.2712903497
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.8911564622
MESH:D005234 Fatty Liver arsenic trioxide 22.9915073043
MESH:D005234 Fatty Liver arsenite 22.9918296743
MESH:D005234 Fatty Liver Ethinyl Estradiol 22.9915345470
MESH:D005234 Fatty Liver pirinixic acid 22.9920131406 19236843
MESH:D005234 Fatty Liver Tamoxifen 22.9914986274 19224547
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 7.8716002989 16513791 15751030 16611131 16534752
MESH:D052776 Female Urogenital Diseases Tamoxifen 7.8716709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.2911858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.3514745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.0119069698
MESH:D005355 Fibrosis arsenite 8.2618296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 8.2620067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.1016904648
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 12.2416452187
MESH:D005833 Genital Neoplasms, Female sodium arsenite 12.2416452187
MESH:D005909 Glioblastoma Genistein 3.1516598420
MESH:D018149 Glucose Intolerance sodium arsenate 4.9219446573
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4210696789
MESH:D006258 Head and Neck Neoplasms decitabine 3.3719215824
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.2411294989 10048152
MESH:D006333 Heart Failure pirinixic acid 2.4320558911
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1811000095
MESH:D006529 Hepatomegaly pirinixic acid 7.7016221962 18467677 19772884 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.7016120746 12621046 15340226
MESH:D006558 Herpes Genitalis Estradiol 4.8615709030
MESH:D006689 Hodgkin Disease sodium arsenite 3.0112676792
MESH:D019584 Hot Flashes Estradiol 3.5817088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.8715340226 18606429 8697196 16959395 16354765
MESH:D006943 Hyperglycemia pirinixic acid 3.0320558911
MESH:D006965 Hyperplasia Diethylstilbestrol 4.2714722030 12960047
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.8418850075 18670907
MESH:D007021 Hypospadias Diethylstilbestrol 10.6716002989
MESH:D007021 Hypospadias Ethinyl Estradiol 10.6716569931 16945680
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.2315869954
MESH:D007246 Infertility Diethylstilbestrol 4.1915036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3012013081
MESH:D007248 Infertility, Male decitabine 15.1517581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 15.1517937319
MESH:D007248 Infertility, Male fulvestrant 15.1511514358
MESH:D007248 Infertility, Male sodium arsenite 15.1512646999 15346721
MESH:D007249 Inflammation Flurbiprofen 18.8411099482
MESH:D007249 Inflammation Progesterone 18.8415869954
MESH:D007249 Inflammation Tamoxifen 18.8419457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 18.8412200463 12878042
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 18.848273558 11698051 15177302 7562506 7812673
MESH:D007249 Inflammation Tobacco Smoke Pollution 18.8418590791
MESH:D007333 Insulin Resistance bisphenol A 11.6716393666
MESH:D007333 Insulin Resistance Estradiol 11.6716393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 11.6716306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.1816580747
MESH:D007674 Kidney Diseases Estradiol 5.7815618244
MESH:D007674 Kidney Diseases sodium arsenite 5.7820008137
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 11.6614681315 16762066 15003126
MESH:D007680 Kidney Neoplasms Estradiol 11.6615610895
MESH:D007680 Kidney Neoplasms Tamoxifen 11.6618625569
MESH:D007859 Learning Disorders Diethylstilbestrol 3.8917184923
MESH:D007938 Leukemia arsenic trioxide 10.0515070760
MESH:D007938 Leukemia decitabine 10.0518980019 19235587
MESH:D007938 Leukemia Genistein 10.0518980019 17468513
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.6412560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute anthra(1,9-cd)pyrazol-6(2H)-one 11.2016972261
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 11.2016972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.3014633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 9.0719077051
MESH:D007951 Leukemia, Myeloid decitabine 9.0717236224 19117987 18454857
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.8816968895 20471514 16467208 17050201 19850784
MESH:D015470 Leukemia, Myeloid, Acute decitabine 3.8817679729 19010910 18460780 18206229 18704418 19387464
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.2918055864
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.1012712474 19225113 11468182 15622746 17107899 17869043 19035177 16330433 16112521 16891316 17712046 16331271 9834237 19075265 19642359 12679006 16823087 17217047 15748426 17649720 11161223 16966277 12018890 15213294 15336539
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.1916882451
MESH:D008064 Lipidoses Tamoxifen 3.0315342952 17567588
MESH:D008103 Liver Cirrhosis arsenite 3.3318296743
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 6.4914716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Genistein 6.4917823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 6.4915474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 6.4918564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 6.4912878042
MESH:D008113 Liver Neoplasms arsenic trioxide 17.1414682389
MESH:D008113 Liver Neoplasms Diethylstilbestrol 17.1415890375 16712894
MESH:D008113 Liver Neoplasms pirinixic acid 17.1420007298 15890375 16377806
MESH:D008113 Liver Neoplasms sodium arsenite 17.1416712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 17.1416684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 17.1416984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 5.4520377131
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 5.4512151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.2215213294
MESH:D008171 Lung Diseases Asbestos, Serpentine 11.8717200189
MESH:D008171 Lung Diseases Ozone 11.878266340 19066396
MESH:D008171 Lung Diseases sodium arsenite 11.8719095001
MESH:D055370 Lung Injury Ozone 3.6820417186
MESH:D008175 Lung Neoplasms arsenic trioxide 15.0219825857 11798837
MESH:D008175 Lung Neoplasms arsenite 15.0216809336
MESH:D008175 Lung Neoplasms Asbestos, Serpentine 15.0211198217
MESH:D008175 Lung Neoplasms Ozone 15.028597069 7614698
MESH:D008175 Lung Neoplasms sodium arsenite 15.0216712894 19931552 17077188 17306315 15276417
MESH:D008175 Lung Neoplasms Tamoxifen 15.0218625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 15.0211884234 19555203
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 15.0211807781
MESH:D008175 Lung Neoplasms Tobacco Smoke Pollution 15.0216288123 12111688 11091918 3440675
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.9815166399
MESH:D008223 Lymphoma decitabine 7.3319470736
MESH:D008223 Lymphoma Diethylstilbestrol 7.3315700306
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.3416002989
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.5919428831
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 17.6717203775 16891317 11408345 11807958
MESH:D008325 Mammary Neoplasms, Experimental Genistein 17.6714578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 17.6711408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 17.6716827153 14580682 11731420 19196723 19196722
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 17.678985016
MESH:D020149 Manganese Poisoning Estradiol 12.0719453300
MESH:D020149 Manganese Poisoning Tamoxifen 12.0719453300
MESH:D008545 Melanoma decitabine 4.9517785578 16505122
MESH:D008545 Melanoma sodium arsenite 4.9519082730 16487513
MESH:D008545 Melanoma Tamoxifen 4.9512393984 19393235
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.0115990972
MESH:D008679 Metaplasia Ozone 4.9310496685
MESH:D009062 Mouth Neoplasms Tobacco Smoke Pollution 4.2215006635
MESH:D009101 Multiple Myeloma arsenic trioxide 6.9719549372 14977855 11468182 15949261 19417148
MESH:D009101 Multiple Myeloma decitabine 6.9718172295
MESH:D009135 Muscular Diseases pirinixic acid 3.3416239165
MESH:D009139 Musculoskeletal Abnormalities sodium arsenate 4.7018186108
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.5018349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 7.1816882451 16105982
MESH:D009190 Myelodysplastic Syndromes decitabine 7.1818608210 19157545 16882708 19010910
MESH:D009203 Myocardial Infarction Genistein 5.4417141266
MESH:D009203 Myocardial Infarction pirinixic acid 5.4419151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.8812213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 13.4116810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 13.4117141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 13.4116411023
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.7916624393
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.4819393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4619410462
MESH:D009369 Neoplasms decitabine 11.1919116145 17925555 19470736
MESH:D009369 Neoplasms Diethylstilbestrol 11.1915313581
MESH:D009369 Neoplasms pirinixic acid 11.1917405874
MESH:D009369 Neoplasms sodium arsenite 11.1911559025
MESH:D009374 Neoplasms, Experimental Asbestos, Serpentine 8.9711704859
MESH:D009374 Neoplasms, Experimental sodium arsenite 8.9720056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.8319196722 19200415 19189210
MESH:D009389 Neovascularization, Pathologic arsenite 9.5815738583
MESH:D009389 Neovascularization, Pathologic Estradiol 9.5817289903
MESH:D009421 Nervous System Malformations bisphenol A 28.9711399458 16427766
MESH:D009421 Nervous System Malformations Diethylstilbestrol 28.9711399458
MESH:D009421 Nervous System Malformations Estradiol 28.9716427766 11399458
MESH:D009421 Nervous System Malformations Genistein 28.9716427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 28.9714600291
MESH:D009436 Neural Tube Defects arsenic trioxide 11.6310525206
MESH:D009436 Neural Tube Defects sodium arsenate 11.6318186108 19446573 11749123 10525206
MESH:D009436 Neural Tube Defects sodium arsenite 11.6312854658
MESH:D009765 Obesity pirinixic acid 1.7720558911
MESH:D010024 Osteoporosis Genistein 3.1519401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 3.9216169203
MESH:D010049 Ovarian Diseases bisphenol A 4.8211985600
MESH:D010051 Ovarian Neoplasms arsenic trioxide 18.1719769630 12452020 16624393
MESH:D010051 Ovarian Neoplasms decitabine 18.1719331143 19259094
MESH:D010051 Ovarian Neoplasms Estradiol 18.1719401270
MESH:D010051 Ovarian Neoplasms Genistein 18.1719005980
MESH:D010051 Ovarian Neoplasms Progesterone 18.1717393432 16525653
MESH:D010051 Ovarian Neoplasms sodium arsenite 18.1717306315 15276417
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 8.3915580305
MESH:D010190 Pancreatic Neoplasms decitabine 8.3919294695
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 8.3915976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5311578682
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 4.1212065085 18922899 8330346 18404319
MESH:D010235 Paraganglioma arsenic trioxide 4.0019927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.0812520081
MESH:D010538 Peritonitis Ozone 3.9616369182
MESH:D010900 Pituitary Diseases Diethylstilbestrol 5.0014722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.5016977796 15687265
MESH:D010995 Pleural Diseases Asbestos, Serpentine 5.5210923243
MESH:D011014 Pneumonia Ozone 4.2218007984 18929643 18381685
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3918163543
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 15.2810548101
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 15.2817184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 15.2811118676 11222880 11896295 11399792
MESH:D055728 Primary Myelofibrosis decitabine 4.5617616702
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 10.0320887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 10.0320887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.4219131511
MESH:D011471 Prostatic Neoplasms bisphenol A 2.4216740699
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 2.4215046698 15846301 17136230
MESH:D011471 Prostatic Neoplasms Estradiol 2.4216740699
MESH:D011471 Prostatic Neoplasms Flurbiprofen 2.4217409433
MESH:D011471 Prostatic Neoplasms Genistein 2.4215378649 15256057 16925846
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.4216039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.4215067354
MESH:D011537 Pruritus Ethinyl Estradiol 3.1416919318 15861022
MESH:D011629 Puberty, Precocious bisphenol A 4.6110548101
MESH:D011658 Pulmonary Fibrosis Asbestos, Serpentine 3.7615511213 18569384
MESH:D015427 Reperfusion Injury pirinixic acid 2.3019058328
MESH:D012130 Respiratory Hypersensitivity trimellitic anhydride 4.7520219652
MESH:D012135 Respiratory Sounds Tobacco Smoke Pollution 4.4518410779
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6718990726
MESH:D012208 Rhabdomyosarcoma decitabine 4.2419155313
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.8018045962
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.7916646077
MESH:D012878 Skin Neoplasms sodium arsenite 12.9818572023 19524636
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 12.9816192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 12.9812065085 11807781 18404319 8330346 8985016
MESH:D012878 Skin Neoplasms Tobacco Smoke Pollution 12.9818590791
MESH:D013088 Spermatocele Diethylstilbestrol 19.1316709447 16002989
MESH:D013088 Spermatocele Ethinyl Estradiol 19.1316709447
MESH:D013088 Spermatocele Tamoxifen 19.1316709447
MESH:D013119 Spinal Cord Injuries Progesterone 10.3015862959 16503802
MESH:D013119 Spinal Cord Injuries Tamoxifen 10.3019457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.6612854658
MESH:D013274 Stomach Neoplasms marker/mechanism 16367923
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.5317007042
MESH:D013274 Stomach Neoplasms decitabine 2.5319037991
MESH:D019966 Substance-Related Disorders bisphenol A 3.8116684133 16045194
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.4611994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0115669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.7312697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 6.8919014326
MESH:D013964 Thyroid Neoplasms decitabine 6.8917967635
MESH:D013978 Tibial Fractures Estradiol 4.5119048282
MESH:D016171 Torsades de Pointes arsenic trioxide 3.7915213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 19.0312973940 20435036 11780464 12845720
MESH:D001749 Urinary Bladder Neoplasms decitabine 19.0317616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 19.0316712894 17306315 16452187
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 19.0316712894 16452187 17306315 11723127
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 19.0317572228 8653321 16712894
MESH:D001749 Urinary Bladder Neoplasms Tobacco Smoke Pollution 19.0312846360
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 9.0416175088
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 9.0411813266
MESH:D014591 Uterine Diseases bisphenol A 13.2414652134
MESH:D014591 Uterine Diseases Diethylstilbestrol 13.2414652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 8.9215809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 8.9214692618
MESH:D014604 Uveal Neoplasms decitabine 4.7417785578
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.2716513791 16002989
MESH:D014652 Vascular Diseases sodium arsenite 4.2517056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4212125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.3814671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.0815886252
No data
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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