AutismKB 2.0

Annotation Detail for SQLE


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SQLE ( FLJ30795 )
Gene Full Name: squalene epoxidase
Band: 8q24.13
Quick LinksEntrez ID:6713; OMIM: 602019; Uniprot ID:ERG1_HUMAN; ENSEMBL ID: ENSG00000104549; HGNC ID: 11279
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PWY66-341cholesterol biosynthesis I
PWY66-4cholesterol biosynthesis III (via desmosterol)
PWY66-3cholesterol biosynthesis II (via 24,25-dihydrolanosterol)
PWY-5670epoxysqualene biosynthesis
Pathway IDPathway Name
hsa01100Metabolic pathways
hsa00100Steroid biosynthesis
Pathway IDPathway Name
Metabolism of lipids and lipoproteins
No data
Pathway IDPathway Name
P00014Cholesterol biosynthesis
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C003585 22-hydroxycholesterol 22-hydroxycholesterol results in decreased expression of SQLE mRNAdecreases expression 19426978
C010914 2,4-diaminotoluene 2,4-diaminotoluene results in decreased expression of SQLE mRNAdecreases expression 20713471
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of SQLE mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of SQLE mRNAaffects expression 21346803
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of SQLE mRNAincreases expression 18648102
D000082 Acetaminophen Acetaminophen results in decreased expression of SQLE mRNAdecreases expression 11793227
D000082 Acetaminophen Acetaminophen affects the expression of SQLE mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of SQLE mRNAaffects expression 16483693
D000965 Antimony Antimony results in decreased expression of SQLE mRNAdecreases expression 17547211
D000966 Antimony Potassium Tartrate Antimony Potassium Tartrate results in decreased expression of SQLE mRNAdecreases expression 17547211
D001554 Benzene Benzene affects the expression of SQLE mRNAaffects expression 15878777
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SQLE mRNAaffects cotreatment|increases expression 18164116
C006780 bisphenol A bisphenol A results in decreased expression of SQLE mRNAdecreases expression 19371625
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of SQLE mRNAincreases expression 15336504
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of SQLE mRNAdecreases expression 14729362
D002110 Caffeine Caffeine results in decreased expression of SQLE mRNAdecreases expression 11793227
D003314 Corn Oil Corn Oil affects the expression of SQLE mRNAaffects expression 16360708
D016572 Cyclosporine Cyclosporine results in decreased expression of SQLE mRNAdecreases expression 20106945
D003907 Dexamethasone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of SQLE mRNAaffects cotreatment|decreases expression 16054899
D004041 Dietary Fats Dietary Fats results in decreased expression of SQLE mRNAdecreases expression 15238619
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SQLE mRNAaffects cotreatment|increases expression 18164116
D004052 Diethylnitrosamine Diethylnitrosamine results in decreased expression of SQLE mRNAdecreases expression 19638242
D002117 Calcitriol Calcitriol results in increased expression of SQLE mRNAincreases expression 16002434
D004128 Dimethylnitrosamine Dimethylnitrosamine results in decreased expression of SQLE mRNAdecreases expression 17547211
D004137 Dinitrochlorobenzene Dinitrochlorobenzene results in increased expression of SQLE mRNAincreases expression 18242016
D004317 Doxorubicin Doxorubicin results in decreased expression of SQLE mRNAdecreases expression 15205334
D004958 Estradiol Estradiol results in increased expression of SQLE mRNAincreases expression 14664709
D000431 Ethanol Ethanol results in increased expression of SQLE mRNAincreases expression 17920746
D000431 Ethanol [Fish Oils co-treated with Ethanol] results in increased expression of SQLE mRNAaffects cotreatment|increases expression 17347304
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of SQLE mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of SQLE mRNAincreases expression 16174780
17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SQLE mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of SQLE mRNAaffects expression 17351261
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of SQLE mRNAdecreases expression 15901920
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of SQLE mRNAincreases expression 16174780
D015025 Zearalenone Zearalenone results in decreased expression of SQLE mRNAdecreases expression 19371625
D005395 Fish Oils [Fish Oils co-treated with Ethanol] results in increased expression of SQLE mRNAaffects cotreatment|increases expression 17347304
D005419 Flavonoids Flavonoids results in decreased expression of SQLE mRNAdecreases expression 18035473
D005472 Fluorouracil Fluorouracil results in decreased expression of SQLE mRNAdecreases expression 15205334
D019833 Genistein Genistein results in decreased expression of SQLE mRNAdecreases expression 19371625
D006861 Hydrogen Peroxide [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SQLE mRNAaffects cotreatment|increases expression 18032389
D006861 Hydrogen Peroxide Hydrogen Peroxide results in decreased expression of SQLE mRNAdecreases expression 14729362
D015056 1-Methyl-3-isobutylxanthine [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of SQLE mRNAaffects cotreatment|decreases expression 16054899
D007529 Isoflavones Isoflavones affects the expression of SQLE mRNAaffects expression 16365062
C016527 isoquercitrin [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SQLE mRNAaffects cotreatment|increases expression 18032389
D001556 Lindane Lindane results in increased expression of SQLE mRNAincreases expression 17785943
D008769 Methylnitronitrosoguanidine Methylnitronitrosoguanidine results in increased expression of SQLE mRNAincreases expression 12634122
C016340 o,p'-DDT o,p'-DDT results in decreased expression of SQLE mRNAdecreases expression 19371625
D010081 Oxazolone Oxazolone results in increased expression of SQLE mRNAincreases expression 18242016
D010126 Ozone Ozone results in decreased expression of SQLE mRNAdecreases expression 16716893
D010269 Paraquat Paraquat affects the expression of SQLE mRNAaffects expression 16854511
C023036 perfluorooctanoic acid perfluorooctanoic acid results in decreased expression of SQLE mRNAdecreases expression 17560707
C023036 perfluorooctanoic acid perfluorooctanoic acid results in increased expression of SQLE mRNAincreases expression 17681415
D010656 Phenylephrine Phenylephrine results in increased expression of SQLE mRNAincreases expression 18158353
D010795 Phthalic Acids Phthalic Acids results in decreased expression of SQLE mRNAdecreases expression 15728792
D010840 Phytosterols APOE gene mutant form affects the reaction [Phytosterols results in increased expression of SQLE mRNA]affects reaction|increases expression 18155511
D010852 Picrotoxin Picrotoxin results in decreased expression of SQLE mRNAdecreases expression 15170462
C006253 pirinixic acid pirinixic acid results in decreased expression of SQLE mRNAdecreases expression 18445702
C006253 pirinixic acid pirinixic acid results in increased expression of SQLE mRNAincreases expression 20059764
11798191
18467677
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in increased expression of SQLE mRNA]increases expression|increases reaction 18467677
20059764
C059514 resveratrol resveratrol results in decreased expression of SQLE mRNAdecreases expression 19371625
C089730 rosiglitazone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of SQLE mRNAaffects cotreatment|decreases expression 16054899
C009250 sevoflurane sevoflurane affects the expression of SQLE mRNAaffects expression 15967596
C446685 systhane systhane results in increased expression of SQLE mRNAincreases expression 19409404
D013629 Tamoxifen Tamoxifen affects the expression of SQLE mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SQLE mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of SQLE mRNAdecreases expression 11752688
D013853 Thioacetamide Thioacetamide results in decreased expression of SQLE mRNAdecreases expression 11793227
D014051 Toluene 2,4-Diisocyanate Toluene 2,4-Diisocyanate results in increased expression of SQLE mRNAincreases expression 18242016
C052342 topiramate topiramate results in decreased expression of SQLE mRNAdecreases expression 16979414
C032910 triadimefon triadimefon results in increased expression of SQLE mRNAincreases expression 17178688
C032910 triadimefon triadimefon results in increased expression of SQLE mRNAincreases expression 19409404
19423681
D014635 Valproic Acid Valproic Acid results in decreased expression of SQLE mRNAdecreases expression 19101580
C088658 zoledronic acid zoledronic acid results in increased expression of SQLE mRNAincreases expression 18325729
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 3.9314745880
MESH:D000014 Abnormalities, Drug-Induced Ethanol 10.7717676605 18926900
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 10.7715322242 14514962 11752688
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 10.778875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.3819490988
MESH:D000138 Acidosis Ammonium Chloride 8.4518287403
MESH:D000138 Acidosis Ethanol 8.4511192467
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.3217505938
MESH:D058186 Acute Kidney Injury resveratrol 7.2616538975
MESH:D058186 Acute Kidney Injury zoledronic acid 7.2619715164
MESH:D055371 Acute Lung Injury pirinixic acid 2.5618653653
MESH:D000210 Acute-Phase Reaction zoledronic acid 4.8720200999
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 14.5016033868
MESH:D000230 Adenocarcinoma Doxorubicin 14.5017418594
MESH:D000230 Adenocarcinoma Estradiol 14.5011473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 14.5014692618
MESH:D000230 Adenocarcinoma Fluorouracil 14.5017638652
MESH:D000230 Adenocarcinoma Genistein 14.5011473722
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 16.973712494
MESH:D000236 Adenoma beta-Naphthoflavone 16.9719389873
MESH:D000236 Adenoma Diethylnitrosamine 16.9710737359 6695378
MESH:D000236 Adenoma Dimethylnitrosamine 16.9719555203
MESH:D000236 Adenoma resveratrol 16.9715688382
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 13.7717620307 18056438 19061943 16434500 19052882 17162532
MESH:D018248 Adenoma, Liver Cell pirinixic acid 13.7716434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 13.7716835633
MESH:D000382 Agricultural Workers' Diseases Lindane 6.9712661182
MESH:D000382 Agricultural Workers' Diseases Paraquat 6.9711874814
MESH:D000419 Albuminuria Doxorubicin 3.9621441931
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.7015451040 15451039
MESH:D000437 Alcoholism topiramate 4.5517925516 18552399 19331489
MESH:D000505 Alopecia Isoflavones 4.2317569567
MESH:D000544 Alzheimer Disease Ozone 5.6815513908
MESH:D000544 Alzheimer Disease resveratrol 5.6816183991 16162502
MESH:D000544 Alzheimer Disease rosiglitazone 5.6819621015
MESH:D000550 Amblyopia Valproic Acid 4.6117688650
MESH:D000740 Anemia Fluorouracil 6.9215504547 16511603 17963324
MESH:D000740 Anemia Tetrachlorodibenzodioxin 6.9211748828
MESH:D000741 Anemia, Aplastic Benzene 3.8917661222 14761424 11369114
MESH:D000799 Angioedema Acetaminophen 3.2210982225
MESH:D000853 Anophthalmos Ethanol 4.2215513904
MESH:D001008 Anxiety Disorders Ethanol 7.3611141031
MESH:D001008 Anxiety Disorders Valproic Acid 7.3617497229
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 3.5817460149
MESH:D001161 Arteriosclerosis Dietary Fats 7.9415238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 7.9411256880
MESH:D001169 Arthritis, Experimental Dexamethasone 10.0017659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 10.0015885639
MESH:D001169 Arthritis, Experimental resveratrol 10.0017115116
MESH:D001172 Arthritis, Rheumatoid Ozone 2.3915570426
MESH:D001249 Asthma Ozone 4.6116373670 17854713
MESH:D001249 Asthma Toluene 2,4-Diisocyanate 4.6119187332 11742282 8156442 10934080 12684321 11467998 12762349 15590890 18394133 3040596 10797510 20032816 6091946 15855793 16210060 11077013 12585506 170078 6091945 7684630 15590891 17015710 16792590
MESH:D050197 Atherosclerosis resveratrol 2.8916873680 17967414
MESH:D001289 Attention Deficit Disorder with Hyperactivity Phthalic Acids 3.9320106747
MESH:D001321 Autistic Disorder Acetaminophen 1.8718445737
MESH:D001321 Autistic Disorder Valproic Acid 1.8717157402 16609825 18316065 18177632 18396377 17507914 19460635 18558336 19232924 18985861 17688650 18940202 18775368 15238991 20603192
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.401440618 11289319
MESH:D001714 Bipolar Disorder Valproic Acid 2.7320046352 17594078
MESH:D001778 Blood Coagulation Disorders pirinixic acid 12.1819483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 12.1812125929
MESH:D001778 Blood Coagulation Disorders Thioacetamide 12.1819483382
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.1715340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 6.6415746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 6.648888407
MESH:D001855 Bone Marrow Diseases Benzene 4.6116183116
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.0814601052
MESH:D001859 Bone Neoplasms zoledronic acid 4.3916778634 16121404 17312309 15867366 19442620 11697798
MESH:D001862 Bone Resorption bisphenol A 7.9811985600
MESH:D001862 Bone Resorption zoledronic acid 7.9818496637 15845617 8053405 18404659 16769263 11869084
MESH:D001919 Bradycardia Phenylephrine 3.9415306635
MESH:D002545 Brain Ischemia resveratrol 3.6817600658
MESH:D001932 Brain Neoplasms Doxorubicin 3.2817150277
MESH:D001943 Breast Neoplasms 2,4-diaminotoluene 14.2711921183
MESH:D001943 Breast Neoplasms Benzene 14.2711921183 17162533
MESH:D001943 Breast Neoplasms bisphenol A 14.2717123778
MESH:D001943 Breast Neoplasms Calcitriol 14.2711237771
MESH:D001943 Breast Neoplasms Dietary Fats 14.2720435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 14.2717474063
MESH:D001943 Breast Neoplasms Doxorubicin 14.2711325840 15136595 16595493 15994142 16115903 16096432 17369602 15634643 17983394 15993339 18628466 18382427 15668708 19526202 18234424 15567936 15939500 16935488 18695136 17426702 16826403 15692762 16322301 16264153
MESH:D001943 Breast Neoplasms Estradiol 14.2717261762 16675129 18497071 12948864 14630087 17289903 17018787 19861407
MESH:D001943 Breast Neoplasms Fluorouracil 14.2716557594 16110121 18608205 18357371 19217205 15136595 16595493
MESH:D001943 Breast Neoplasms Genistein 14.2716541309 17200150 16873071
MESH:D001943 Breast Neoplasms Lindane 14.2714688026
MESH:D001943 Breast Neoplasms resveratrol 14.2717534123 17651959 16393696
MESH:D001943 Breast Neoplasms Tamoxifen 14.2720859285 19200415 20135344 16202921 18629630 17440819 18425577 15565566 17261762 19011961 19244106 19221464 17049068 20544844 19410462 18815881 18351453 17893378 11161223 15668708 19155303 19115204 18821012 19189210 16273361 16873071 16818667 19189212 19288272 21152245 18997820 19084267 17242785 20390343 19103187 19142967 19289846 18855134 20065188 21138602 19066611 19487384 19059307 18984771 20005174
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 14.2720435547
MESH:D001943 Breast Neoplasms Toluene 2,4-Diisocyanate 14.2711921183
MESH:D001943 Breast Neoplasms zoledronic acid 14.2718695136 16096432
MESH:D016535 Bronchial Hyperreactivity Ozone 7.2915516495 16777450 18315731 18417511 14754758 17626835 19059883
MESH:D016535 Bronchial Hyperreactivity Toluene 2,4-Diisocyanate 7.2912507178 8156442 15590891
MESH:D001991 Bronchitis Antimony 5.518768112
MESH:D002056 Burns Ethanol 4.0616374292
MESH:D002100 Cachexia Ozone 4.1316183385
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.8516111702
MESH:D002276 Carcinoid Tumor Doxorubicin 10.2916051944
MESH:D002276 Carcinoid Tumor Fluorouracil 10.2916051944
MESH:D002277 Carcinoma Dimethylnitrosamine 11.1619555203
MESH:D002277 Carcinoma Fluorouracil 11.1617121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 11.1616835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 3.9119066611
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 28.8516705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 28.8516705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 28.853581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 28.853084413
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 28.8510672840 20514400 18691550 19822196 16698587 20214788 20084675 16935385 17162532 18506893 10737359 16502159 19519916 16288022 18971187 3084413 16681979 21159647 16540662 17138121 18056438 20007298 18785209 19052882 19418558 16807293 18978308 11831363 16830150 16779866 18665156 17428255 3581430 20935162 19335982 19701751 19208518 17978847 17055752 16328049 19107877 17173139 19919837 16878318 20432363 20524982 19383236 16569478 18494052 18788625 19394651 19539802 20101231 18393292 20512989 19171122 20727157 17761372 18210153
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 28.8516023760 16234567 17876044 18059187
MESH:D006528 Carcinoma, Hepatocellular Estradiol 28.8516924424
MESH:D006528 Carcinoma, Hepatocellular Ethanol 28.8515763234 18788625 15289165
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 28.8517088986 17045692 16799960 16332177 18930000 17971768
MESH:D006528 Carcinoma, Hepatocellular Genistein 28.8516924424
MESH:D006528 Carcinoma, Hepatocellular resveratrol 28.8516227395 19321006
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 28.8516924424
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 28.8517997003
MESH:D002278 Carcinoma in Situ bisphenol A 4.3817123778
MESH:D018827 Carcinoma, Lewis Lung resveratrol 3.9816675471
MESH:D002289 Carcinoma, Non-Small-Cell Lung zoledronic acid 3.3019233551
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 12.737296757
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 12.731485588 16201981
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 12.7318695887
MESH:D002292 Carcinoma, Renal Cell zoledronic acid 12.7318507039
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 11.9611237771
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 11.9616033868
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 11.966189445
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 11.9616757204 16280240 18986760 17066447
MESH:D002294 Carcinoma, Squamous Cell resveratrol 11.9616227395
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.0817572228
MESH:D006332 Cardiomegaly Ethanol 9.3419332462
MESH:D006332 Cardiomegaly Phenylephrine 9.3417124262 15728586 17287366 16170337 11754973 11179087
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 9.3416120746 18670907 18850075
MESH:D009202 Cardiomyopathies Doxorubicin 3.1117329180 15476868 16952015 18627295 15792986 16731534 17007740 17974986 17382496 17351982 16278810 15505089 16612575 17519947 16364871 16109756 15811867 17928571 17131338 17924179 16242529 17308081 16455267 16651473 16269455
MESH:D002311 Cardiomyopathy, Dilated Antimony 5.5110334427
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 5.5117334414 16243910
MESH:D002318 Cardiovascular Diseases Genistein 13.7916332659
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 13.7916936243
MESH:D002318 Cardiovascular Diseases Isoflavones 13.7917689850
MESH:D002318 Cardiovascular Diseases resveratrol 13.7915458977
MESH:D002386 Cataract Acetaminophen 2.2010977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 20.696135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 20.697505956
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 20.6912371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 20.692727394 7505956 21159647 17174075
MESH:D002471 Cell Transformation, Neoplastic Estradiol 20.6918566989
MESH:D002471 Cell Transformation, Neoplastic Methylnitronitrosoguanidine 20.692727394
MESH:D002659 Child Development Disorders, Pervasive topiramate 5.5415650499
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 5.5420734317
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 13.1219052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 13.1216835633
MESH:D018281 Cholangiocarcinoma Thioacetamide 13.1218291259
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 15.4019486331 9022650
MESH:D002779 Cholestasis Cyclosporine 15.4019486331
MESH:D002779 Cholestasis Ethinyl Estradiol 15.4015861022 16105132 17110522 17681005 11677210 16919318 17333356
MESH:D002779 Cholestasis pirinixic acid 15.4019176532
MESH:D002971 Cleft Lip Ethanol 3.2315513904
MESH:D002972 Cleft Palate Ethanol 8.2615513904
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 8.2612621046 16354765 15668235 15340226 8697196
MESH:D002972 Cleft Palate triadimefon 8.2616781842
MESH:D003092 Colitis resveratrol 3.5416474422
MESH:D003093 Colitis, Ulcerative Dinitrochlorobenzene 3.6117373747 19159591
MESH:D003110 Colonic Neoplasms Dexamethasone 7.0415824018
MESH:D003110 Colonic Neoplasms Fluorouracil 7.0417016597 16340194 17018589 16510598 17725105 17287894 17169374 18772588 17172411 15001691
MESH:D003110 Colonic Neoplasms Genistein 7.0417182828
MESH:D003110 Colonic Neoplasms resveratrol 7.0416338953
MESH:D015179 Colorectal Neoplasms Doxorubicin 4.2018802399 18259882
MESH:D015179 Colorectal Neoplasms Fluorouracil 4.2018448328 17016601 18288408 16331619 16282729 14970324 16391804 18383874 16524972 17401013 18949393 17255274 17594712 18802399 15148649 15289873 20501625 17454858 18509181 17094418 16303861 17695437
MESH:D015179 Colorectal Neoplasms Isoflavones 4.2017116718
MESH:D015179 Colorectal Neoplasms resveratrol 4.2016550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.5417141729 14669216
MESH:D003327 Coronary Disease resveratrol 3.3416507316
MESH:D019465 Craniofacial Abnormalities Benzene 8.2115643154
MESH:D019465 Craniofacial Abnormalities Dexamethasone 8.2117728286
MESH:D019465 Craniofacial Abnormalities Ethanol 8.2115451040 15451039 10194807 19302082 15513904 11198716 11873399
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 8.2120055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities triadimefon 8.2116875885 15834900
MESH:D019465 Craniofacial Abnormalities Valproic Acid 8.2116575769 17688650 8888407
MESH:D003490 Cyanosis 2,4-dinitrotoluene 8.9218551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 8.9218551238
MESH:D007644 Darier Disease Fluorouracil 4.1816733453
MESH:D003711 Demyelinating Diseases Tamoxifen 3.7719031437
MESH:D003872 Dermatitis Benzene 4.1715902427
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 11.8418759878 14531868 12868966 8156756 2524372 11298694 11906362 8970840
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 11.8412438553
MESH:D017449 Dermatitis, Allergic Contact Dinitrochlorobenzene 11.8415491423
MESH:D017449 Dermatitis, Allergic Contact Toluene 2,4-Diisocyanate 11.8412956900 15491423 18759878
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.1118249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 12.633621924 2952479
MESH:D003877 Dermatitis, Contact Oxazolone 12.6312811023 15944321
MESH:D003877 Dermatitis, Contact Toluene 2,4-Diisocyanate 12.6317010967
MESH:D003920 Diabetes Mellitus rosiglitazone 3.7817446233
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.2716873680
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 11.5620387270
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 11.5616647724
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 11.5612642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 11.5617107852
MESH:D003924 Diabetes Mellitus, Type 2 topiramate 11.5616979414
MESH:D003928 Diabetic Nephropathies Estradiol 12.0319279558
MESH:D003928 Diabetic Nephropathies resveratrol 12.0316286809
MESH:D003928 Diabetic Nephropathies Tamoxifen 12.0319279558
MESH:D003967 Diarrhea Dexamethasone 3.147237001
MESH:D004283 Dog Diseases Antimony 5.0512019027
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 28.0418551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 28.0418551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 28.0418692083 6482804 18289764 11289319 9022650 1440618 8291058 18648102 9653073 7440962 6679447 9328219 16192314
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 28.0411421492 16109766 19923254 19416960 11739529 17906064 12540782 11287661 2444490 12705907 14550746 10915739 19164858 16781746 19420014 11461765 12958197 14725611 15619225 16081117 16227642 18713872 19085960 10663392 15968718 18071297 19370779 19739265 17562736 17522070 14986274 11834606 11529661 16485898 16177239 12392966 12594235 11743745 16393943 10774834 12153990
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 28.0419107877
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 28.048172417
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 28.0417416283
MESH:D056486 Drug-Induced Liver Injury Ethanol 28.0411566570
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 28.0420420201
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 28.0412963478
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 28.0419641884 1733752
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.4819426721
MESH:D004362 Drug Toxicity Doxorubicin 6.5618602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 6.5611462148
MESH:D050171 Dyslipidemias Dietary Fats 3.0018367378
MESH:D004421 Dystonia Valproic Acid 3.491851702
MESH:D004485 Eczema Dexamethasone 3.8812438553
MESH:D004487 Edema Dexamethasone 20.0519703484
MESH:D004487 Edema perfluorooctanoic acid 20.0517259670 12083418
MESH:D004487 Edema pirinixic acid 20.0512083418
MESH:D004487 Edema resveratrol 20.058985016
MESH:D004487 Edema rosiglitazone 20.0512083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 20.0512711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.2818230668 16714409 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 17.2115138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 17.2112538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 17.2117872969
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 17.2119031437
MESH:D004714 Endometrial Hyperplasia Genistein 3.9816402032
MESH:D016889 Endometrial Neoplasms Doxorubicin 14.3417359293
MESH:D016889 Endometrial Neoplasms Estradiol 14.3411473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Genistein 14.3411473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 14.3420544844 17893378 19155303 16202921
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.4910568697 9294722
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.5318037988
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.2517923197
MESH:D004802 Eosinophilia Toluene 2,4-Diisocyanate 4.078156442
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 3.5617275665 3659116
MESH:D004828 Epilepsies, Partial Valproic Acid 3.303922381 16628512
MESH:D004827 Epilepsy topiramate 6.0319148780
MESH:D004827 Epilepsy Valproic Acid 6.0320417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 3.077562514 6254150 6426943
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 3.707750514
MESH:D004833 Epilepsy, Temporal Lobe topiramate 5.6516499746
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 3.463659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.4916302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 8.773581430
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 8.7717016578
MESH:D004938 Esophageal Neoplasms Ethanol 8.7716704527
MESH:D004938 Esophageal Neoplasms Fluorouracil 8.7716337965 16785472 16481741 17638652 15173087
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.5511564622
MESH:D005128 Eye Diseases Toluene 2,4-Diisocyanate 5.1418447907
MESH:D005218 Fat Necrosis Thioacetamide 5.1016456712
MESH:D005234 Fatty Liver Cyclosporine 44.5319224547
MESH:D005234 Fatty Liver Dietary Fats 44.5318296743 19551842 17967931 19004024
MESH:D005234 Fatty Liver Diethylnitrosamine 44.5321071580 20387270
MESH:D005234 Fatty Liver Ethanol 44.5318620774 19236843 16409862
MESH:D005234 Fatty Liver Ethinyl Estradiol 44.5315345470
MESH:D005234 Fatty Liver Fish Oils 44.5318620774
MESH:D005234 Fatty Liver pirinixic acid 44.5320131406 19236843
MESH:D005234 Fatty Liver rosiglitazone 44.5319196556
MESH:D005234 Fatty Liver Tamoxifen 44.5314986274 19224547
MESH:D005234 Fatty Liver Valproic Acid 44.5314986274 19224547
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.0417920746
MESH:D052776 Female Urogenital Diseases Tamoxifen 2.8416709447
MESH:D005264 Femoral Fractures zoledronic acid 5.2216234978
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.6915451040 16946407 15513904 10194807
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.8611858732
MESH:D005315 Fetal Diseases Valproic Acid 4.2716575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 3.558888407 18558336
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.406705139
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 3.9214745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 9.4219069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 9.4219069698
MESH:D005355 Fibrosis Cyclosporine 11.3012639820 12168785
MESH:D005355 Fibrosis Dietary Fats 11.3018296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 11.3020067830
MESH:D005756 Gastritis Acetaminophen 9.0716983495
MESH:D005756 Gastritis Ethanol 9.0715046732
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.618708960
MESH:D005909 Glioblastoma Doxorubicin 5.9417150277
MESH:D005909 Glioblastoma Genistein 5.9416598420
MESH:D005910 Glioma Fluorouracil 2.6016145905
MESH:D005911 Gliosis Paraquat 4.5411124998
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.477505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.9710696789
MESH:D006258 Head and Neck Neoplasms Doxorubicin 6.4815692506
MESH:D006258 Head and Neck Neoplasms Fluorouracil 6.4815162350 18337622 15102660
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 1.9810048152 11294989
MESH:D006331 Heart Diseases Doxorubicin 3.0514766674 18006777 18674790 16495754 12587719 16244372 16330681 17875725 16244371 16144979 16707910 16879835 17888722
MESH:D006333 Heart Failure Doxorubicin 5.7117481944
MESH:D006333 Heart Failure pirinixic acid 5.7120558911
MESH:D006394 Hemangiosarcoma Doxorubicin 3.3615692506
MESH:D006402 Hematologic Diseases Benzene 4.0916183116
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.8115720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.7911000095
MESH:D006501 Hepatic Encephalopathy Thioacetamide 4.0217276928 15929193 18665440
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 12.576705139
MESH:D006505 Hepatitis Caffeine 12.5711394713
MESH:D006505 Hepatitis Thioacetamide 12.5716456712
MESH:D006529 Hepatomegaly perfluorooctanoic acid 20.923609246
MESH:D006529 Hepatomegaly pirinixic acid 20.9216221962 19772884 18467677 19176532
MESH:D006529 Hepatomegaly systhane 20.9217178689 17178688
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 20.9215340226 16120746 12621046
MESH:D006529 Hepatomegaly triadimefon 20.9217178689 17178688
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 2.827520565
MESH:D006558 Herpes Genitalis Estradiol 4.4115709030
MESH:D006561 Herpes Simplex resveratrol 3.5816876885
MESH:D006689 Hodgkin Disease Doxorubicin 2.9115147373 18501091 17606976
MESH:D019584 Hot Flashes Estradiol 8.3617088409
MESH:D019584 Hot Flashes Isoflavones 8.3617290160 14716179
MESH:D006849 Hydrocephalus Valproic Acid 4.2617688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.4215340226 16354765 8697196 18606429 16959395
MESH:D006930 Hyperalgesia Acetaminophen 19.3516870215
MESH:D006930 Hyperalgesia Ethanol 19.3518783367
MESH:D006930 Hyperalgesia perfluorooctanoic acid 19.3512083418
MESH:D006930 Hyperalgesia rosiglitazone 19.3512083418
MESH:D006930 Hyperalgesia zoledronic acid 19.3516769263
MESH:D006934 Hypercalcemia zoledronic acid 4.5018089816 19622757
MESH:D006937 Hypercholesterolemia Dietary Fats 7.4021332399
MESH:D006937 Hypercholesterolemia resveratrol 7.4017188708
MESH:D006943 Hyperglycemia pirinixic acid 2.6520558911
MESH:D006949 Hyperlipidemias Dietary Fats 12.3521332399
MESH:D006949 Hyperlipidemias Fish Oils 12.3515752949
MESH:D006949 Hyperlipidemias resveratrol 12.3516873680
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.3515034207
MESH:D006967 Hypersensitivity Toluene 2,4-Diisocyanate 4.0711019492 10880147
MESH:D006968 Hypersensitivity, Delayed Corn Oil 10.6311484837
MESH:D006968 Hypersensitivity, Delayed Fish Oils 10.6311484837
MESH:D006973 Hypertension Benzene 13.4717940673
MESH:D006973 Hypertension Cyclosporine 13.4710903974
MESH:D006973 Hypertension Dexamethasone 13.4717042910
MESH:D006973 Hypertension Phenylephrine 13.4712717712 8949925
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 13.4718670907 18850075
MESH:D006984 Hypertrophy Phenylephrine 4.0112791704 18502941
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 3.7717488730
MESH:D006996 Hypocalcemia zoledronic acid 5.5712669777
MESH:D007021 Hypospadias Ethinyl Estradiol 3.2116569931 16945680
MESH:D007077 Ileal Diseases 1-Methyl-3-isobutylxanthine 4.8218306037
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.0517600658
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.9012013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 5.3217937319
MESH:D007248 Infertility, Male Paraquat 5.324850670
MESH:D007249 Inflammation Dexamethasone 26.1811099482 8960868
MESH:D007249 Inflammation Dietary Fats 26.1820412841
MESH:D007249 Inflammation Diethylnitrosamine 26.1818785209
MESH:D007249 Inflammation Flavonoids 26.1817296493
MESH:D007249 Inflammation perfluorooctanoic acid 26.1812083418
MESH:D007249 Inflammation resveratrol 26.1816366677
MESH:D007249 Inflammation rosiglitazone 26.1812083418
MESH:D007249 Inflammation Tamoxifen 26.1819457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 26.1812200463 12878042
MESH:D007251 Influenza, Human resveratrol 3.9316624496
MESH:D007333 Insulin Resistance bisphenol A 18.7416393666
MESH:D007333 Insulin Resistance Dietary Fats 18.7418457598 11836018
MESH:D007333 Insulin Resistance Estradiol 18.7416393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 18.7416306350
MESH:D007333 Insulin Resistance rosiglitazone 18.7416306350
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.408074119 9022650
MESH:D007569 Jaw Abnormalities Ethanol 14.1615513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 14.1616580747
MESH:D007569 Jaw Abnormalities triadimefon 14.1615834900 15992940
MESH:D007579 Jejunal Diseases 1-Methyl-3-isobutylxanthine 4.8218306037
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.8215604871
MESH:D007674 Kidney Diseases Acetaminophen 11.2915629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 11.2918776723 10903974 8314463
MESH:D007674 Kidney Diseases Doxorubicin 11.2916775033 15369732 15699352
MESH:D007674 Kidney Diseases Estradiol 11.2915618244
MESH:D007676 Kidney Failure, Chronic Doxorubicin 8.3116707910
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 8.3116518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 27.4016705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 27.4016705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 27.406582329
MESH:D007680 Kidney Neoplasms Cyclosporine 27.4012371664
MESH:D007680 Kidney Neoplasms Estradiol 27.4015610895
MESH:D007680 Kidney Neoplasms Fluorouracil 27.4016985049
MESH:D007680 Kidney Neoplasms Tamoxifen 27.4018625569
MESH:D007859 Learning Disorders Ethanol 8.0815451040
MESH:D007859 Learning Disorders sevoflurane 8.0819212262
MESH:D007896 Leishmaniasis Antimony 4.3012019027 15220340 21063981 10953559 21182181
MESH:D016773 Leishmaniasis, Cutaneous Antimony 4.1711475954 8889330 19141829
MESH:D007897 Leishmaniasis, Mucocutaneous Antimony 4.887854095 11370249 10651420 10881086 9643325
MESH:D007898 Leishmaniasis, Visceral Antimony 7.168142506 11105143 7554475 7854095 1899875 20495762 7875148
MESH:D007898 Leishmaniasis, Visceral Antimony Potassium Tartrate 7.1612707265
MESH:D007938 Leukemia Benzene 5.5117119257 14694614 15935818 18335105
MESH:D007938 Leukemia Genistein 5.5118980019 17468513
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.5316085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell zoledronic acid 4.2218089816
MESH:D007951 Leukemia, Myeloid Benzene 3.7717506065
MESH:D015470 Leukemia, Myeloid, Acute Benzene 3.6219478238
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 3.6216294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Antimony Potassium Tartrate 6.879834237
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 6.8716087638
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 4.628812269
MESH:D017880 Limb Deformities, Congenital Ethanol 3.3617676605
MESH:D008064 Lipidoses Tamoxifen 2.7117567588 15342952
MESH:D008103 Liver Cirrhosis Dietary Fats 8.9518296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 8.9518522880 20032147 18407596 18665156 19638242
MESH:D008103 Liver Cirrhosis Ethanol 8.9515289165
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.4918295389
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.7915034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 18.2516718785
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 18.2516627068 14659978 14643895 17465448 15577212 15161499 16009107 16570917 17036385 15479170 18672772 18629640 15492853 18210741 17201889 15086199 17348192 17196135 18239293 16544323 17203207 15339415 16603200 15298665 17198567 17719030 18364076 15366600 16169303 15067225 15591649 15793283 14726149 16270385 15864749 15138612 15763062 17640959 15383259 16042886 14709902 15723089 15571005 15942678 15081153 15733078 17666798 18371158 14568256 18567088 15369754 17881167 17432682 17534399 18095165 15744066 17724770 12925901 18237412 12918455 18637143 15504291 15842777 15798949 15099470
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 18.2516595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 18.2514716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 18.2518166357
MESH:D008106 Liver Cirrhosis, Experimental Genistein 18.2517823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 18.2515474484
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 18.2517347453 15980055
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 18.2518564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 18.2512878042
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 18.2512175628 11172339 16511523 17127702 12557150 12679928 18458672 15288472 16248980 18263696 14739098 15334695 15465738 17050028 18615449 15474484 17292413 18032466 16097051 17629604 12891558 15158331 18031379 16126171 15716488 17355460 10677585 18380797 12085344 15095483 18606216 15075984 16489207 16343077 15362042 11682029 11481614 16098781 15316131 18416461 15288473 18295389 18395095 12531686 15078482
MESH:D008107 Liver Diseases Acetaminophen 10.3719460945 12969438 12587719 16611625 19014921 19784758 11587558 16610002
MESH:D008107 Liver Diseases Diethylnitrosamine 10.3717034775
MESH:D008107 Liver Diseases Lindane 10.371715830
MESH:D008107 Liver Diseases Thioacetamide 10.3715158337 16337175 18374380
MESH:D008107 Liver Diseases triadimefon 10.3719363144
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.0617207112 17347304
MESH:D017114 Liver Failure, Acute Acetaminophen 13.2716871587 17185352
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 13.2717457977
MESH:D017114 Liver Failure, Acute Thioacetamide 13.2717276928 15313186 15633222 12479984
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 32.137678174
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 32.1321295105 19389873
MESH:D008113 Liver Neoplasms Diethylnitrosamine 32.1319551842 19690152 15175105 20137499 19642983 18644402 21167192 12112319 19850985 19427195 10737359 19833225 20405173 18754104 21047994 19073162 2862719 19638242 20492335 16942905 19254457 19499222 20501860 18977376 20583210 19426721 19255062 19256749 20434301 20452335 15885732 12771043 18648771 21278145 2422723 19812893 20101389 9163691 19090486 19294768 20118626 18978307 21071580 19996281
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 32.133113478 15890375
MESH:D008113 Liver Neoplasms Fluorouracil 32.1318383874 17045692 16603448 15113037
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 32.1318709148 14757943
MESH:D008113 Liver Neoplasms pirinixic acid 32.1315890375 16377806 20007298
MESH:D008113 Liver Neoplasms resveratrol 32.1319073162 19812893 19321006 20405173
MESH:D008113 Liver Neoplasms Tamoxifen 32.1316684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 32.1316984957
MESH:D008113 Liver Neoplasms triadimefon 32.1319028983
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 34.792876786 6135515 2876784
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 34.79598648 3712494 6587162 1399818
MESH:D008114 Liver Neoplasms, Experimental Benzene 34.7912562636
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 34.7918164116
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 34.7917942915 18775883 17174075 19539802 2563599 19126423 18308698 18164116 19519916 16267830 17854601 19009564 18282651 18093689 9362446 18253720 19004024 18079962 16842330 18544905 21159647 3124819
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 34.791848544 6150874 15603536
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 34.7916842330 17085340
MESH:D008114 Liver Neoplasms, Experimental systhane 34.7917178689
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 34.7912151625
MESH:D008114 Liver Neoplasms, Experimental triadimefon 34.7917178689
MESH:D008171 Lung Diseases Ozone 2.9519066396 8266340
MESH:D017563 Lung Diseases, Interstitial Benzene 9.3314698565
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 9.3317228818
MESH:D055370 Lung Injury Ozone 3.2620417186
MESH:D008175 Lung Neoplasms Benzene 13.2512562636
MESH:D008175 Lung Neoplasms Dexamethasone 13.2511195469 15824018
MESH:D008175 Lung Neoplasms Diethylnitrosamine 13.256695378 20970405 20512841 21163286
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 13.2519555203 11884234 16061637
MESH:D008175 Lung Neoplasms Doxorubicin 13.2517418594 6189445
MESH:D008175 Lung Neoplasms Fluorouracil 13.2515246190
MESH:D008175 Lung Neoplasms Ozone 13.257614698 8597069
MESH:D008175 Lung Neoplasms Tamoxifen 13.2518625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 13.2511884234 19555203
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.1815086387
MESH:D008223 Lymphoma Benzene 6.3417119257 17584886
MESH:D008223 Lymphoma Doxorubicin 6.3416098063
MESH:D016393 Lymphoma, B-Cell resveratrol 3.7417088997
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 7.2117654614
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 7.2114749477
MESH:D016399 Lymphoma, T-Cell Doxorubicin 3.9715621674
MESH:D015674 Mammary Neoplasms, Animal Benzene 13.3112562636
MESH:D015674 Mammary Neoplasms, Animal resveratrol 13.3115688416
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 13.3119428831
MESH:D008325 Mammary Neoplasms, Experimental 2,4-diaminotoluene 30.5311921183
MESH:D008325 Mammary Neoplasms, Experimental Benzene 30.5311921183
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 30.5315458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 30.5311408345 16891317 17203775 11807958
MESH:D008325 Mammary Neoplasms, Experimental Genistein 30.5314578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 30.5311606380 8985016
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 30.5316827153
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 30.5314580682 19196723 11731420 16827153 19196722
MESH:D008325 Mammary Neoplasms, Experimental zoledronic acid 30.5317312309
MESH:D020149 Manganese Poisoning Estradiol 10.5819453300
MESH:D020149 Manganese Poisoning Tamoxifen 10.5819453300
MESH:D008545 Melanoma Dinitrochlorobenzene 6.1612202904 17334785
MESH:D008545 Melanoma Doxorubicin 6.1616827129
MESH:D008545 Melanoma resveratrol 6.1617992120
MESH:D008545 Melanoma Tamoxifen 6.1612393984 19393235
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.5715990972
MESH:D008546 Melanoma, Experimental Acetaminophen 2.9719513568
MESH:D008569 Memory Disorders Ethanol 8.0618411066 15451040
MESH:D008569 Memory Disorders sevoflurane 8.0619212262
MESH:D008654 Mesothelioma Doxorubicin 5.6917638057
MESH:D008654 Mesothelioma zoledronic acid 5.6916675582
MESH:D008659 Metabolic Diseases resveratrol 3.8317112576
MESH:D024821 Metabolic Syndrome X rosiglitazone 3.8717261469
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.1716801185
MESH:D008679 Metaplasia Ozone 4.4810496685
MESH:D053842 Microsatellite Instability Methylnitronitrosoguanidine 5.2817671175
MESH:D008881 Migraine Disorders topiramate 6.5518759728 16942474 18765137 18803445
MESH:D008881 Migraine Disorders Valproic Acid 6.5518765137 18803445
MESH:D028361 Mitochondrial Diseases Doxorubicin 3.9515792986
MESH:D009062 Mouth Neoplasms Fluorouracil 3.1616757204 18986760
MESH:D052016 Mucositis Doxorubicin 4.1817415656
MESH:D009101 Multiple Myeloma Benzene 13.6717119195
MESH:D009101 Multiple Myeloma Dexamethasone 13.6715867202 16118317 15744524
MESH:D009101 Multiple Myeloma resveratrol 13.6717164350 16490592 14749477 17049120 17935668 16267019
MESH:D009101 Multiple Myeloma zoledronic acid 13.6716996129 18089719 19621390
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.2617962980
MESH:D009135 Muscular Diseases pirinixic acid 2.9116239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.488888407
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 6.309809623
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 6.3017596541
MESH:D009203 Myocardial Infarction Doxorubicin 11.1315857846 19429709
MESH:D009203 Myocardial Infarction Genistein 11.1317141266
MESH:D009203 Myocardial Infarction pirinixic acid 11.1319151258
MESH:D009203 Myocardial Infarction resveratrol 11.1316456233 16317513 17188708 17125593 17015251 16525036
MESH:D017202 Myocardial Ischemia resveratrol 7.3817125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 7.3812213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 11.4016810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 11.4017141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 11.4016411023
MESH:D009205 Myocarditis resveratrol 4.1517322642
MESH:D009336 Necrosis 2,4-dinitrotoluene 8.3318551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 8.337678174 18551238
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 14.903581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 14.903581430 9029167
MESH:D009362 Neoplasm Metastasis Doxorubicin 14.9018259882
MESH:D009362 Neoplasm Metastasis Tamoxifen 14.9019393235
MESH:D009362 Neoplasm Metastasis zoledronic acid 14.9015867366 19139120 17312309
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.2819410462
MESH:D009369 Neoplasms Fluorouracil 6.4318600527 18239605 16928823
MESH:D009369 Neoplasms Lindane 6.4312807735 16818664
MESH:D009369 Neoplasms pirinixic acid 6.4317405874
MESH:D009374 Neoplasms, Experimental resveratrol 7.668985016
MESH:D009374 Neoplasms, Experimental Toluene 2,4-Diisocyanate 7.661670384
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.3819196722 19189210 19200415
MESH:D009389 Neovascularization, Pathologic Estradiol 3.1317289903
MESH:D009401 Nephrosis Doxorubicin 4.1716636307 16899518
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.8217954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 7.5718481113 19348381
MESH:D009404 Nephrotic Syndrome Doxorubicin 7.5716889571 15640375
MESH:D009410 Nerve Degeneration Paraquat 3.2416893418
MESH:D009421 Nervous System Malformations bisphenol A 18.7111399458 16427766
MESH:D009421 Nervous System Malformations Estradiol 18.7116427766 11399458
MESH:D009421 Nervous System Malformations Genistein 18.7116427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 18.7114600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 9.776679447
MESH:D009436 Neural Tube Defects Benzene 9.7715643154
MESH:D009436 Neural Tube Defects Valproic Acid 9.7716359493 8888407
MESH:D009447 Neuroblastoma Doxorubicin 2.9215555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 11.1518514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 11.1520387270
MESH:D019636 Neurodegenerative Diseases resveratrol 11.1517652729
MESH:D020078 Neurogenic Inflammation resveratrol 3.8417929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.4920387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.0116436463
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 4.369802331
MESH:D009765 Obesity Dietary Fats 3.7920518802 18674790 18457598 19632207 11836018 21332399 16723640 20132043 17217161
MESH:D009765 Obesity pirinixic acid 3.7920558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 22.6812819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 22.6816049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 22.684026338 6482804
MESH:D009784 Occupational Diseases Benzene 22.6815935809 15576619 17178637 17119257 17479406 16737584 15612468 15913788 15727169
MESH:D009784 Occupational Diseases Toluene 2,4-Diisocyanate 22.688156442 11077013 6091945 3040596 6091946 18394133 12585506
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.403988306
MESH:D010014 Osteolysis zoledronic acid 4.7615867366
MESH:D010024 Osteoporosis Genistein 9.8019401787
MESH:D010024 Osteoporosis Isoflavones 9.8016562857
MESH:D010024 Osteoporosis zoledronic acid 9.8017882678
MESH:D015663 Osteoporosis, Postmenopausal Genistein 8.2816169203
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 8.2817513867
MESH:D012516 Osteosarcoma Doxorubicin 3.6215930896
MESH:D010049 Ovarian Diseases bisphenol A 4.3811985600
MESH:D010051 Ovarian Neoplasms Benzene 6.6012562636
MESH:D010051 Ovarian Neoplasms Estradiol 6.6019401270
MESH:D010051 Ovarian Neoplasms Genistein 6.6019005980
MESH:D010146 Pain Acetaminophen 5.3416870215
MESH:D010146 Pain zoledronic acid 5.3416475674
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 7.1716540662
MESH:D010190 Pancreatic Neoplasms Ethanol 7.1712384795
MESH:D010190 Pancreatic Neoplasms Fluorouracil 7.1715113037 16929163 19003803 16500647
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.1211578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 7.357296757
MESH:D010212 Papilloma Hydrogen Peroxide 7.3512065085
MESH:D010300 Parkinson Disease Paraquat 2.5615824117 11445065 15451049 11124998 16140633 11181820 16510128 12911755
MESH:D010302 Parkinson Disease, Secondary Paraquat 3.8416190885
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.6312520081
MESH:D010409 Penile Diseases Antimony 5.149643325
MESH:D010493 Pericarditis Antimony 5.5020465667
MESH:D010538 Peritonitis Ozone 3.5416369182
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 3.856228378
MESH:D003557 Phyllodes Tumor Doxorubicin 4.5317983394
MESH:D010997 Pleural Neoplasms Doxorubicin 4.5317638057
MESH:D011014 Pneumonia Ozone 9.0518381685 18929643 18007984
MESH:D011014 Pneumonia Paraquat 9.0512504350
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.9818163543
MESH:D011230 Precancerous Conditions Corn Oil 12.4714668109
MESH:D011230 Precancerous Conditions Cyclosporine 12.4712371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 12.472563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.1821297632
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 24.0510548101
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 24.0517132714
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 24.0516679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 24.0511399792 11896295 11222880 11118676
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 24.0520603192
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.1715572423
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 8.7320887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 8.7320887781
MESH:D011471 Prostatic Neoplasms bisphenol A 3.7616740699
MESH:D011471 Prostatic Neoplasms Calcitriol 3.7615754350 16644109 16289102 12479363 18247401
MESH:D011471 Prostatic Neoplasms Doxorubicin 3.7616729912 15749863 16868541 16888761 18437689 15897917
MESH:D011471 Prostatic Neoplasms Estradiol 3.7616740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 3.7618626508 19082440
MESH:D011471 Prostatic Neoplasms Genistein 3.7615256057 15378649 16925846
MESH:D011471 Prostatic Neoplasms Isoflavones 3.7617219775 17571952 17374662 16365062
MESH:D011471 Prostatic Neoplasms Lindane 3.7612661182 14688026
MESH:D011471 Prostatic Neoplasms resveratrol 3.7616731767 17636462 17718901 17804756 17675339 15767336
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.7615067354
MESH:D011471 Prostatic Neoplasms zoledronic acid 3.7612438248 19103299
MESH:D011537 Pruritus Ethinyl Estradiol 2.7115861022 16919318
MESH:D019310 Pseudolymphoma Valproic Acid 3.9212752131 11422049
MESH:D011565 Psoriasis Cyclosporine 1.9816882103
MESH:D011629 Puberty, Precocious bisphenol A 4.1810548101
MESH:D011657 Pulmonary Eosinophilia Toluene 2,4-Diisocyanate 5.0014606601
MESH:D011658 Pulmonary Fibrosis Paraquat 2.6516324872 17997886
MESH:D012004 Rectal Neoplasms Fluorouracil 3.4916160472 18722050 18286688 15538739
MESH:D051437 Renal Insufficiency Doxorubicin 3.6317922066
MESH:D051436 Renal Insufficiency, Chronic resveratrol 4.9616325855
MESH:D015427 Reperfusion Injury pirinixic acid 5.4519058328
MESH:D015427 Reperfusion Injury resveratrol 5.4517520802 17058453 16314181 16317513 15827377
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 7.4018379247 11700416
MESH:D012128 Respiratory Distress Syndrome, Adult Paraquat 7.4011700416
MESH:D012130 Respiratory Hypersensitivity Toluene 2,4-Diisocyanate 4.0120219652 16940033 7692837
MESH:D012135 Respiratory Sounds Paraquat 3.4711874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.2618990726
MESH:D012140 Respiratory Tract Diseases Toluene 2,4-Diisocyanate 4.5018447907
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 7.363692021
MESH:D012162 Retinal Degeneration Paraquat 7.3616458197
MESH:D012208 Rhabdomyosarcoma Valproic Acid 3.6119155313
MESH:D012220 Rhinitis Toluene 2,4-Diisocyanate 4.0519050374
MESH:D012221 Rhinitis, Allergic, Perennial Toluene 2,4-Diisocyanate 4.6612617775 15015336
MESH:D006255 Rhinitis, Allergic, Seasonal Toluene 2,4-Diisocyanate 4.8919075512
MESH:D012509 Sarcoma Doxorubicin 3.4615625365 15675481 17203757 17710206 18313854 16767912
MESH:D012512 Sarcoma, Ewing's Doxorubicin 8.7116326096 14601052
MESH:D012512 Sarcoma, Ewing's zoledronic acid 8.7116121404
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.1817846226
MESH:D012559 Schizophrenia Valproic Acid 1.9815737665 19110320
MESH:D012640 Seizures 2,4-dinitrotoluene 21.5418551238
MESH:D012640 Seizures 2,6-dinitrotoluene 21.5418551238
MESH:D012640 Seizures Ethanol 21.549754883
MESH:D012640 Seizures Lindane 21.5415475178 7539098 12842176
MESH:D012640 Seizures Picrotoxin 21.548954991 8635557
MESH:D012640 Seizures topiramate 21.5416499746
MESH:D012640 Seizures Valproic Acid 21.5415475178 14763951 11738929 16876388 11044598 1511512 3137016 17978042
MESH:D012852 Sinusitis Phenylephrine 4.107327846
MESH:D012878 Skin Neoplasms Doxorubicin 14.4815692506
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 14.4812065085
MESH:D012878 Skin Neoplasms resveratrol 14.488985016 15837718
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 14.488532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 14.4816192470
MESH:D012893 Sleep Disorders Caffeine 4.7119395429
MESH:D007319 Sleep Initiation and Maintenance Disorders Caffeine 4.4917225163
MESH:D012912 Sneezing Toluene 2,4-Diisocyanate 4.8919050374 19075512
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 3.9717203757 15625365 16767912
MESH:D013088 Spermatocele Ethinyl Estradiol 9.5016709447
MESH:D013088 Spermatocele Tamoxifen 9.5016709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.4319457130
MESH:D016135 Spinal Dysraphism Valproic Acid 3.3019490988
MESH:D013158 Splenic Diseases Dimethylnitrosamine 4.6512587719
MESH:D013226 Status Epilepticus Valproic Acid 3.9212833885
MESH:D013272 Stomach Diseases Dexamethasone 3.7215472012
MESH:D013274 Stomach Neoplasms Benzene 5.4912562636
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 5.4918456281
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 5.4916033868
MESH:D013274 Stomach Neoplasms Ethanol 5.4918456281
MESH:D013274 Stomach Neoplasms Fluorouracil 5.4916424979 18567086 15786421 18396642 19084572 16951190 17498489 19015929 17172411 17522103
MESH:D013276 Stomach Ulcer Dexamethasone 5.7715138204
MESH:D013276 Stomach Ulcer Ethanol 5.779562338 11906479 17189318 16755016 9211565 17918041
OMIM:601367 STROKE, ISCHEMIC resveratrol 3.9416321402
MESH:D019966 Substance-Related Disorders bisphenol A 3.3816684133 16045194
MESH:D013375 Substance Withdrawal Syndrome Ethanol 3.729754883
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.0611994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.6415669648
MESH:D013953 Thymus Neoplasms Benzene 4.3510850423
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.2812697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 13.281399818 7505956 3712494 6582329 6587162
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 13.287505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 13.2816010429 17909728
MESH:D013964 Thyroid Neoplasms triadimefon 13.2817178689
MESH:D013978 Tibial Fractures Estradiol 4.0619048282
MESH:D014062 Tongue Neoplasms Fluorouracil 8.2116280240
MESH:D014062 Tongue Neoplasms resveratrol 8.2116227395
MESH:D014178 Translocation, Genetic Valproic Acid 4.6117262798
MESH:D014352 Trypanosomiasis Antimony 5.3115220340
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 3.913119515
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 12.7916049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 12.7916049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 12.798074119
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 12.7917653716
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 12.798653321 17572228 16712894
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.058888407
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 9.9710091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 9.9710091137
MESH:D014581 Urticaria Acetaminophen 2.4210982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 7.8416803524
MESH:D002583 Uterine Cervical Neoplasms resveratrol 7.8417473185
MESH:D014591 Uterine Diseases bisphenol A 4.3914652134
MESH:D014594 Uterine Neoplasms Benzene 12.7712562636
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 12.7714692618
MESH:D014594 Uterine Neoplasms resveratrol 12.7717044934
MESH:D014605 Uveitis Cyclosporine 9.711336536
MESH:D014605 Uveitis Dexamethasone 9.711336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.9712125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.9915869587 14671159
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 8.3717678736 17334414 16364871 17638931
MESH:D018487 Ventricular Dysfunction, Left resveratrol 8.3717488730
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.6315886252
MESH:D015430 Weight Gain Dietary Fats 3.2216723640
MESH:D014985 Xerophthalmia Cyclosporine 3.8217120751
Pathway ID Pathway Name
KEGG:01100 Metabolic pathways
REACT:22258 Metabolism of lipids and lipoproteins
KEGG:00100 Steroid biosynthesis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA36108
  • No data
    Releated disease ID Related disease Name
    PA445425Prostatic Neoplasms
    No data
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00735 inhibitor Naftifine Antifungal Agents
    DB00857 inhibitor Terbinafine Antifungals;Enzyme Inhibitors;Antifungal Agents;Trypanocidal Agents;Allylamines
    DB01091 inhibitor Butenafine Antifungal Agents
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018