AutismKB 2.0

Annotation Detail for BRAF


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Basic Information Top
Gene Symbol:BRAF ( B-RAF1,BRAF1,FLJ95109,MGC126806,MGC138284,RAFB1 )
Gene Full Name: v-raf murine sarcoma viral oncogene homolog B1
Band: 7q34
Quick LinksEntrez ID:673; OMIM: 164757; Uniprot ID:BRAF_HUMAN; ENSEMBL ID: ENSG00000157764; HGNC ID: 1097
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04914Progesterone-mediated oocyte maturation
hsa05160Hepatitis C
hsa04270Vascular smooth muscle contraction
hsa04910Insulin signaling pathway
hsa04012ErbB signaling pathway
hsa04010MAPK signaling pathway
hsa04150mTOR signaling pathway
hsa04720Long-term potentiation
hsa04650Natural killer cell mediated cytotoxicity
hsa04730Long-term depression
hsa05219Bladder cancer
hsa04722Neurotrophin signaling pathway
hsa05211Renal cell carcinoma
hsa05216Thyroid cancer
hsa05223Non-small cell lung cancer
hsa05221Acute myeloid leukemia
hsa05220Chronic myeloid leukemia
hsa04810Regulation of actin cytoskeleton
hsa05218Melanoma
hsa05212Pancreatic cancer
hsa05213Endometrial cancer
hsa05210Colorectal cancer
hsa05214Glioma
hsa05215Prostate cancer
hsa04510Focal adhesion
hsa04062Chemokine signaling pathway
hsa05200Pathways in cancer
Pathway IDPathway Name
Signalling by NGF
Pathway IDPathway Name
200182Trk receptor signaling mediated by the MAPK pathway
200184Downstream signaling in naive CD8+ T cells
200088Ras signaling in the CD4+ TCR pathway
200080mTOR signaling pathway
200113ErbB1 downstream signaling
200192Signaling events mediated by focal adhesion kinase
200057CDC42 signaling events
Pathway IDPathway Name
P00053T cell activation
P00056VEGF signaling pathway
P00018EGF receptor signaling pathway
P00005Angiogenesis
P00047PDGF signaling pathway
P00034Integrin signalling pathway
P00036Interleukin signaling pathway
P04393Ras Pathway
Pathway IDPathway Name
500628Signalling to p38 via RIT and RIN
500630Frs2-mediated activation
500631ARMS-mediated activation
Related Diseases/Disorders Top
Desease IDDesease Name
Cancers
Skin cancers
H00032Thyroid cancer
H00038Malignant melanoma
Cancers of endocrine organs
Desease IDDesease Name
1758Common cold
1886Angiomyolipoma
1934Cancer
1946Thyroid gland disease
1979Testicular dysfunction
1982Myopathy
2003Metaplastic polyp
2094Ulcerative colitis
2203Nephrosis
Desease Name
colorectal cancer
CANCER
No data
Desease Name
Cardiofaciocutaneous syndrome
Colorectal cancer, somatic
Melanoma, malignant, somatic
Nonsmall cell lung cancer, somatic
Adenocarcinoma of lung, somatic
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of BRAF mRNAaffects expression 21346803
C027576 4-hydroxy-2-nonenal 4-hydroxy-2-nonenal results in decreased expression of BRAF mRNAdecreases expression 12419474
D000082 Acetaminophen Acetaminophen affects the expression of BRAF mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of BRAF mRNAaffects expression 16483693
D001151 Arsenic Arsenic results in decreased expression of BRAF mRNAdecreases expression 19654921
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of BRAF mRNAdecreases expression 12419474
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of BRAF mRNAaffects expression 17555576
C015329 lycopene lycopene results in decreased expression of BRAF proteindecreases expression 17337101
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of BRAF mRNAaffects binding|decreases expression|increases activity 19710929
D018038 Sodium Selenite Sodium Selenite results in increased expression of BRAF mRNAincreases expression 16705456
C471405 sorafenib sorafenib binds to and results in decreased activity of BRAF proteinaffects binding|decreases activity 16940797
D013629 Tamoxifen Tamoxifen affects the expression of BRAF mRNAaffects expression 17555576
D014212 Tretinoin Tretinoin results in decreased expression of BRAF mRNAdecreases expression 17045167
D014638 Vanadates Vanadates results in increased expression of BRAF proteinincreases expression 17874149
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.6414745880
MESH:D000138 Acidosis Ammonium Chloride 3.6418287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.0417505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.1718653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8214692618
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.5616434500
MESH:D018246 Adrenocortical Adenoma Arsenic 5.3117306315
MESH:D000505 Alopecia Tretinoin 3.6615955085
MESH:D000690 Amyotrophic Lateral Sclerosis 4-hydroxy-2-nonenal 4.1310965797
MESH:D000799 Angioedema Acetaminophen 3.9410982225
MESH:D020261 Arsenic Poisoning Arsenic 2.8816835338 12569548 16251483 18414634
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.5411256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.3115885639
MESH:D001169 Arthritis, Experimental Tretinoin 7.3116412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2716292516
MESH:D001249 Asthma Tretinoin 2.3616456186
MESH:D050197 Atherosclerosis Arsenic 3.2819371607 12928151
MESH:D001321 Autistic Disorder Acetaminophen 1.4118445737
MESH:D001471 Barrett Esophagus Tretinoin 4.4716935849
MESH:D001778 Blood Coagulation Disorders pirinixic acid 9.1619483382
MESH:D001778 Blood Coagulation Disorders Tretinoin 9.1616206674 16197459
MESH:D001943 Breast Neoplasms Tamoxifen 2.1621138602 18351453 17049068 16273361 20065188 19289846 20859285 11161223 19221464 20005174 16873071 18984771 19200415 20135344 19084267 19103187 16818667 18425577 19288272 19115204 18997820 15668708 19410462 16202921 19189210 15565566 19244106 20544844 19059307 18629630 17242785 18855134 20390343 19155303 21152245 19142967 18815881 17440819 19487384 17261762 17893378 19189212 19066611 19011961 18821012
MESH:D001943 Breast Neoplasms Tretinoin 2.1616443354 16166294 16873071
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.6716813970
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.6215504454 17687452
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.5819066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.2616168501
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 8.9616705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 8.963084413
MESH:D006528 Carcinoma, Hepatocellular Arsenic 8.9617306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 8.9616924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 8.961917145
MESH:D002294 Carcinoma, Squamous Cell Arsenic 4.8515504454 17687452 18922899
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 4.8516096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Arsenic 9.6718640142
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 9.6717572228
MESH:C535579 Cardiofaciocutaneous syndrome marker/mechanism 16439621 17703371
MESH:D002318 Cardiovascular Diseases Arsenic 3.4815738583 19152805 17938729
MESH:D002340 Carotid Artery Diseases Arsenic 4.3618022660 16973168
MESH:D002386 Cataract Acetaminophen 7.3310977129
MESH:D002386 Cataract Tretinoin 7.3317460283
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 2.816135515
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.6716129372
MESH:D002779 Cholestasis Ethinyl Estradiol 7.8817110522 17681005 15861022 16919318 17333356 16105132 11677210
MESH:D002779 Cholestasis pirinixic acid 7.8819176532
MESH:D002822 Choriocarcinoma Tretinoin 5.2616461808
MESH:D019457 Chromosome Breakage Sodium Selenite 4.8215894690
MESH:D002972 Cleft Palate Tretinoin 2.699407595
MESH:D003092 Colitis Tretinoin 3.7817035595
MESH:D015179 Colorectal Neoplasms marker/mechanism 18718023
MESH:D056685 Costello Syndrome marker/mechanism 17703371
MESH:D019465 Craniofacial Abnormalities Tretinoin 1.829142499 9211117 16925845 9125849 8800419 9664655 10589399 14991402 17551590 9224671
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.0918551238
MESH:D003711 Demyelinating Diseases Tamoxifen 4.4319031437
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4518249437
MESH:D003920 Diabetes Mellitus Sodium Selenite 3.8216285004
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.5219279558
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 6.3018551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.3011834606 12594235 18071297 11739529 11461765 11529661 19416960 19923254 16227642 2444490 14986274 10663392 12705907 18713872 17522070 19420014 11421492 11287661 15968718 14550746 14725611 17906064 16781746 19164858 12392966 12540782 16081117 11743745 16109766 12153990 12958197 10915739 19370779 19739265 16485898 10774834 17562736 15619225 19085960 16393943 16177239
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 6.3015131321
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.1919426721
MESH:D004487 Edema pirinixic acid 2.5312083418
MESH:D004489 Edema, Cardiac Tretinoin 4.5618230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 9.1612538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 9.1619031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 7.5519155303 20544844 16202921 17893378
MESH:D016889 Endometrial Neoplasms Tretinoin 7.5516569247
MESH:D005124 Eye Abnormalities Tretinoin 3.6216938888 9664655
MESH:D005234 Fatty Liver Ethinyl Estradiol 13.3715345470
MESH:D005234 Fatty Liver pirinixic acid 13.3719236843 20131406
MESH:D005234 Fatty Liver Tamoxifen 13.3714986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.2716709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.6114745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.2619069698
MESH:D005355 Fibrosis Tretinoin 3.5817994277
MESH:D005534 Foot Diseases Arsenic 5.666392382
MESH:D005756 Gastritis Acetaminophen 3.7716983495
MESH:D005909 Glioblastoma Tretinoin 3.0417312396
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.2216096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.2616084493
MESH:D006330 Heart Defects, Congenital Tretinoin 2.929664655 14991402
MESH:D006333 Heart Failure pirinixic acid 2.5720558911
MESH:D006529 Hepatomegaly pirinixic acid 3.0718467677 19772884 16221962 19176532
MESH:D006930 Hyperalgesia Acetaminophen 7.7716870215
MESH:D006930 Hyperalgesia Tretinoin 7.7716870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.6416778211
MESH:D006943 Hyperglycemia pirinixic acid 3.2320558911
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.5117050553
MESH:D006973 Hypertension Arsenic 2.8916076760 11953799 9931084
MESH:D006987 Hypesthesia Arsenic 5.6616093927
MESH:D007021 Hypospadias Ethinyl Estradiol 3.8816945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.5212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.5217937319
MESH:D007249 Inflammation Tamoxifen 2.3819457130
MESH:D007333 Insulin Resistance pirinixic acid 7.4216306350
MESH:D007333 Insulin Resistance Sodium Selenite 7.4214714311
MESH:D007410 Intestinal Diseases Tretinoin 3.8417994277
MESH:D007569 Jaw Abnormalities Tretinoin 3.9517551590 15992940
MESH:D007642 Keratosis Arsenic 5.0716930632 12749816
MESH:D007674 Kidney Diseases Acetaminophen 2.2315629191 12587719
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 7.5416705839
MESH:D007680 Kidney Neoplasms Tamoxifen 7.5418625569
MESH:D007938 Leukemia Tretinoin 2.7917143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.7519285840 16932348 16482212
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0816294345 19850784 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 7.8717339181
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 7.8716331271 16140955 15748426 17217047 16788101 9834237 17301526 19035177 17368321 17339181 19029980 17361223 16766008 17294898 19225113 16823087 12679006 17107899 19075265 19642359 17506722 17649720 16935935 17712046 16891316
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.349224671
MESH:D008064 Lipidoses Tamoxifen 3.1915342952 17567588
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 3.4915474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 3.4918564211
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 3.4916248980 18397230
MESH:D008107 Liver Diseases Acetaminophen 4.1112969438 16611625 19014921 12587719 19460945 19784758 11587558 16610002
MESH:D008107 Liver Diseases Arsenic 4.1111134558
MESH:D017114 Liver Failure, Acute Acetaminophen 3.2917185352 16871587
MESH:D008113 Liver Neoplasms marker/mechanism 17514646
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 10.887678174
MESH:D008113 Liver Neoplasms Arsenic 10.8816368122
MESH:D008113 Liver Neoplasms pirinixic acid 10.8815890375 16377806 20007298
MESH:D008113 Liver Neoplasms Tamoxifen 10.8816684651
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.572876786 2876784 6135515
MESH:D008175 Lung Neoplasms marker/mechanism
MESH:D008175 Lung Neoplasms Arsenic 2.6219168569 17306315 17976673
MESH:D008175 Lung Neoplasms Tamoxifen 2.6218625569
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.1214737004
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.8419428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.6611731420 19196722 14580682 16827153 19196723
MESH:D020149 Manganese Poisoning Tamoxifen 4.6419453300
MESH:D008527 Medulloblastoma Tretinoin 2.8017453147
MESH:D008545 Melanoma marker/mechanism 19282848 21499247 18421705
MESH:D008545 Melanoma sorafenib 5.4718445842
MESH:D008545 Melanoma Tamoxifen 5.4712393984 19393235
MESH:D008545 Melanoma Tretinoin 5.4716752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.2615990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.6419513568
MESH:D008591 Meningomyelocele Tretinoin 4.5016940565
MESH:D009135 Muscular Diseases pirinixic acid 3.5816239165
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.1117596541
MESH:D009203 Myocardial Infarction pirinixic acid 2.1619151258
MESH:D017202 Myocardial Ischemia Arsenic 4.0315371236
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.9916411023
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.9418551238 7678174
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.5619393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5319410462
MESH:D009369 Neoplasms lycopene 8.5517051425
MESH:D009369 Neoplasms pirinixic acid 8.5517405874
MESH:D009369 Neoplasms Tretinoin 8.5516594593 16946489
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.1019200415 19189210 19196722
MESH:D009421 Nervous System Malformations Tretinoin 3.849125849
MESH:D009436 Neural Tube Defects Arsenic 7.5416620997
MESH:D009436 Neural Tube Defects Tretinoin 7.549142499
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.9118514411
MESH:D020078 Neurogenic Inflammation Arsenic 4.4317056641
MESH:D009634 Noonan Syndrome marker/mechanism 17703371
MESH:D009765 Obesity pirinixic acid 1.8220558911
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.4816049721
MESH:D010051 Ovarian Neoplasms Arsenic 5.0517306315
MESH:D010051 Ovarian Neoplasms Tretinoin 5.0516936753
MESH:D010146 Pain Acetaminophen 6.7416870215
MESH:D010146 Pain Tretinoin 6.7416870215
MESH:D010190 Pancreatic Neoplasms Tretinoin 2.4815976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.7511578682
MESH:D010523 Peripheral Nervous System Diseases Arsenic 4.2416093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 5.0716905509 15371236 6392382
MESH:D010787 Photosensitivity Disorders 4-hydroxy-2-nonenal 5.6011550810
MESH:D011471 Prostatic Neoplasms Arsenic 2.1516140617
MESH:D011471 Prostatic Neoplasms lycopene 2.1517337101 15084515
MESH:D011471 Prostatic Neoplasms Sodium Selenite 2.1518760546
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.1515067354
MESH:D011507 Proteinuria Arsenic 9.4821343184
MESH:D011507 Proteinuria Tretinoin 9.4816636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.3915861022 16919318
MESH:D011625 Pterygium Tretinoin 4.8816723453
MESH:D015427 Reperfusion Injury pirinixic acid 2.4119058328
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.1616283617 16116481
MESH:D012640 Seizures 2,6-dinitrotoluene 2.5718551238
MESH:D012871 Skin Diseases Arsenic 2.766392382 17453740 16702368 17050553 19834688 15952646 16353154 18709164 16759981 17938729 17548696
MESH:D012878 Skin Neoplasms Arsenic 9.7017029826 17050553 15504454 16251483 19538983 17976673
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 9.708532709
MESH:D012878 Skin Neoplasms Tretinoin 9.7016467112
MESH:D013088 Spermatocele Ethinyl Estradiol 11.8916709447
MESH:D013088 Spermatocele Tamoxifen 11.8916709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.1219457130
MESH:D013274 Stomach Neoplasms Tretinoin 1.8017261132
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.2015669648
MESH:D013964 Thyroid Neoplasms marker/mechanism 16940797
MESH:D013964 Thyroid Neoplasms Tretinoin 3.0617045167 16026305
MESH:D014062 Tongue Neoplasms Tretinoin 3.8416051514
MESH:D014376 Tuberculosis Tretinoin 3.2616040207
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 8.4816049721
MESH:D001749 Urinary Bladder Neoplasms Arsenic 8.4819322015 19429237 11144890 18640142 17306315 15987713 17976673
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 8.4817572228 8653321 16712894
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.4010091137
MESH:D014581 Urticaria Acetaminophen 3.0310982225
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.7316129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.3614692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.7116752155
MESH:D014652 Vascular Diseases Arsenic 4.8217056641
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5914671159 15869587
MESH:D014820 Vitiligo Tretinoin 4.1216761959
MESH:D009396 Wilms Tumor Tretinoin 4.0216287080
Pathway ID Pathway Name
KEGG:05221 Acute myeloid leukemia
KEGG:05219 Bladder cancer
KEGG:04062 Chemokine signaling pathway
KEGG:05220 Chronic myeloid leukemia
KEGG:05210 Colorectal cancer
KEGG:05213 Endometrial cancer
KEGG:04012 ErbB signaling pathway
KEGG:04510 Focal adhesion
KEGG:05214 Glioma
KEGG:05160 Hepatitis C
KEGG:04910 Insulin signaling pathway
KEGG:04730 Long-term depression
KEGG:04720 Long-term potentiation
KEGG:04010 MAPK signaling pathway
KEGG:05218 Melanoma
KEGG:04150 mTOR signaling pathway
KEGG:04650 Natural killer cell mediated cytotoxicity
KEGG:04722 Neurotrophin signaling pathway
KEGG:05223 Non-small cell lung cancer
KEGG:05212 Pancreatic cancer
KEGG:05200 Pathways in cancer
KEGG:04914 Progesterone-mediated oocyte maturation
KEGG:05215 Prostate cancer
KEGG:04810 Regulation of actin cytoskeleton
KEGG:05211 Renal cell carcinoma
REACT:11061 Signalling by NGF
REACT:13685 Synaptic Transmission
KEGG:05216 Thyroid cancer
KEGG:04270 Vascular smooth muscle contraction
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA25408
    • No data
    Releated disease ID Related disease Name
    PA446108Colorectal Neoplasms
    PA152208657Cardio-facio-cutaneous Syndrome
    PA446696Nevi and Melanomas
    PA444903Melanoma
    PA445123Noonan Syndrome
    PA445857Thyroid Neoplasms
    Releated drug ID Related drug Name
    PA10040cetuximab
    PA450085irinotecan
    PA7000sorafenib
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00398 antagonist Sorafenib Antineoplastic Agents;Protein Kinase Inhibitors;Anticancer Agents
    DB06999 - N-{3-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide
    DB07000 - N-{2,4-difluoro-3-[(5-pyridin-3-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]phenyl}ethanesulfonamide
    DB07438 - 4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE
    DB08553 - (1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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