AutismKB 2.0

Annotation Detail for STAT1


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Basic Information Top
Gene Symbol:STAT1 ( DKFZp686B04100,ISGF-3,STAT91 )
Gene Full Name: signal transducer and activator of transcription 1, 91kDa
Band: 2q32.2
Quick LinksEntrez ID:6772; OMIM: 600555; Uniprot ID:STAT1_HUMAN; ENSEMBL ID: ENSG00000115415; HGNC ID: 11362
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05160Hepatitis C
hsa05140Leishmaniasis
hsa05145Toxoplasmosis
hsa04620Toll-like receptor signaling pathway
hsa04630Jak-STAT signaling pathway
hsa05212Pancreatic cancer
hsa04062Chemokine signaling pathway
hsa05200Pathways in cancer
Pathway IDPathway Name
Signaling by PDGF
Pathway IDPathway Name
200034IL12-mediated signaling events
200189FGF signaling pathway
200131IL23-mediated signaling events
200156Signaling events mediated by Stem cell factor receptor (c-Kit)
200157EPO signaling pathway
200015GMCSF-mediated signaling events
200127PDGFR-beta signaling pathway
200124IL6-mediated signaling events
200082IL2-mediated signaling events
200083CXCR4-mediated signaling events
200085EGF receptor (ErbB1) signaling pathway
200086TNF receptor signaling pathway
200065Signaling events mediated by TCPTP
200077Glucocorticoid receptor regulatory network
200113ErbB1 downstream signaling
200110IFN-gamma pathway
200023IL27-mediated signaling events
Pathway IDPathway Name
P00035Interferon-gamma signaling pathway
P00046Oxidative stress response
P04398p53 pathway feedback loops 2
P00018EGF receptor signaling pathway
P00005Angiogenesis
P00047PDGF signaling pathway
P00038JAK/STAT signaling pathway
P00036Interleukin signaling pathway
P04393Ras Pathway
No data
Related Diseases/Disorders Top
Desease IDDesease Name
H00089IFN-gamma/IL-12 axis
Immune system diseases
Primary immunodeficiency
No data
No data
No data
Desease Name
STAT1 deficiency, complete
Mycobacterial infection, atypical, familial disseminated
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C097240 15-deoxy-delta(12,14)-prostaglandin J2 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL6 protein results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 12847270
C097240 15-deoxy-delta(12,14)-prostaglandin J2 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased activity of and results in increased localization of [STAT1 protein binds to STAT1 protein]]affects binding|decreases reaction|increases activity|increases localization 12847270
C097240 15-deoxy-delta(12,14)-prostaglandin J2 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 12847270
C097240 15-deoxy-delta(12,14)-prostaglandin J2 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [peroxyvanadate results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 12847270
C097240 15-deoxy-delta(12,14)-prostaglandin J2 Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]decreases reaction|increases phosphorylation 12847270
C097240 15-deoxy-delta(12,14)-prostaglandin J2 CAT protein inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]decreases reaction|increases phosphorylation 12847270
C097240 15-deoxy-delta(12,14)-prostaglandin J2 Glutathione inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]decreases reaction|increases phosphorylation 12847270
C097240 15-deoxy-delta(12,14)-prostaglandin J2 Hydrogen Peroxide promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]decreases reaction|increases phosphorylation|increases reaction 12847270
C097240 15-deoxy-delta(12,14)-prostaglandin J2 peroxyvanadate inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]decreases reaction|increases phosphorylation 12847270
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of STAT1 mRNAincreases expression 19933214
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of STAT1 mRNAaffects expression 21346803
C019499 2-nitrofluorene 2-nitrofluorene results in increased expression of STAT1 mRNAincreases expression 14600272
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in increased expression of STAT1 mRNAincreases expression 16788091
C016601 4-hydroxytamoxifen 4-hydroxytamoxifen results in decreased expression of STAT1 mRNAdecreases expression 16514628
C016583 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of STAT1 proteinincreases activity 16582591
C016583 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of STAT1 mRNAincreases expression 16835749
16582591
C016583 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone Bungarotoxins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of STAT1 protein]decreases reaction|increases activity 16582591
C016583 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone Bungarotoxins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of STAT1 mRNA]decreases reaction|increases expression 16835749
C016583 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone Mecamylamine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of STAT1 protein]decreases reaction|increases activity 16582591
C105260 4-tert-octylphenol 4-tert-octylphenol results in decreased expression of STAT1 mRNAdecreases expression 17011747
C105260 4-tert-octylphenol 4-tert-octylphenol results in increased expression of STAT1 mRNAincreases expression 17011747
C056165 acetovanillone acetovanillone inhibits the reaction [vanadium pentoxide results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 18322232
D000111 Acetylcysteine Acetylcysteine inhibits the reaction [Ozone results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 19061877
D000111 Acetylcysteine Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]decreases reaction|increases phosphorylation 12847270
D000111 Acetylcysteine Acetylcysteine promotes the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]increases phosphorylation|increases reaction 12847270
D000111 Acetylcysteine Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 17607690
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of STAT1 proteinaffects expression 20106945
C103303 alitretinoin alitretinoin results in increased phosphorylation of and results in increased activity of STAT1 proteinincreases activity|increases phosphorylation 16085646
D000493 Allopurinol Allopurinol inhibits the reaction [vanadium pentoxide results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 18322232
C095512 alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [IFNA1 protein results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 15937643
C095512 alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [IFNB1 protein results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 15937643
C095512 alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 15937643
C095512 alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Ozone results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 19061877
C095512 alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 17607690
C068073 Am 580 Am 580 results in increased phosphorylation of and results in increased activity of STAT1 proteinincreases activity|increases phosphorylation 16085646
C068073 Am 580 Ro 41-5253 inhibits the reaction [Am 580 results in increased phosphorylation of and results in increased activity of STAT1 protein]decreases reaction|increases activity|increases phosphorylation 16085646
D000643 Ammonium Chloride Ammonium Chloride affects the expression of STAT1 mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide promotes the reaction [IFNG protein results in increased activity of STAT1 protein]increases activity|increases reaction 14668793
C006632 arsenic trioxide arsenic trioxide promotes the reaction [[IFNG protein results in increased activity of STAT1 protein] which results in increased expression of IRF1 mRNA]increases activity|increases expression|increases reaction 14668793
C006632 arsenic trioxide arsenic trioxide promotes the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]increases phosphorylation|increases reaction 16914093
C015001 arsenite arsenite results in decreased expression of STAT1 mRNAdecreases expression 18929588
C015001 arsenite TRP53 protein affects the reaction [arsenite results in decreased expression of STAT1 mRNA]affects reaction|decreases expression 18929588
D001554 Benzene Benzene results in increased expression of STAT1 mRNAincreases expression 15122651
15120971
C030233 benzo(a)pyrene-1,6-quinone benzo(a)pyrene-1,6-quinone results in increased phosphorylation of STAT1 proteinincreases phosphorylation 19166869
C018003 benzo(a)pyrene-3,6-quinone benzo(a)pyrene-3,6-quinone results in increased phosphorylation of STAT1 proteinincreases phosphorylation 19166869
D001564 Benzo(a)pyrene Benzo(a)pyrene affects the activity of STAT1 proteinaffects activity 20624995
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of STAT1 mRNAincreases expression 19152381
D001564 Benzo(a)pyrene chlorophyllin inhibits the reaction [Benzo(a)pyrene results in increased expression of STAT1 mRNA]decreases reaction|increases expression 19152381
D002038 Bungarotoxins Bungarotoxins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of STAT1 protein]decreases reaction|increases activity 16582591
D002038 Bungarotoxins Bungarotoxins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of STAT1 mRNA]decreases reaction|increases expression 16835749
D002038 Bungarotoxins Bungarotoxins inhibits the reaction [N'-nitrosonornicotine results in increased activity of STAT1 protein]decreases reaction|increases activity 16582591
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of STAT1 mRNAdecreases expression 15336504
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of STAT1 mRNAincreases expression 14729362
15003993
D002104 Cadmium Cadmium inhibits the reaction [CNTF protein results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 16843830
D002104 Cadmium Cadmium inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 16843830
D019256 Cadmium Chloride Cadmium Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 16843830
D019256 Cadmium Chloride Cadmium Chloride inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 16843830
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of STAT1 mRNAincreases expression 16644059
D002392 Catechin Catechin results in decreased expression of STAT1 mRNAdecreases expression 15465739
D002392 Catechin Catechin results in decreased expression of STAT1 proteindecreases expression 15465739
C007020 chlorophyllin chlorophyllin inhibits the reaction [Benzo(a)pyrene results in increased expression of STAT1 mRNA]decreases reaction|increases expression 19152381
C074702 chromium hexavalent ion chromium hexavalent ion results in increased phosphorylation of and affects the localization of STAT1 proteinaffects localization|increases phosphorylation 17078813
C074702 chromium hexavalent ion STAT1 protein affects the reaction [chromium hexavalent ion inhibits the reaction [Nickel results in increased expression of VEGFA mRNA]]affects reaction|decreases reaction|increases expression 19403854
C074702 chromium hexavalent ion STAT1 protein affects the reaction [chromium hexavalent ion inhibits the reaction [Nickel results in increased stability of and results in increased expression of HIF1A protein]]affects reaction|decreases reaction|increases expression|increases stability 19403854
C074702 chromium hexavalent ion STAT1 protein affects the reaction [chromium hexavalent ion results in decreased expression of VEGFA mRNA]affects reaction|decreases expression 19403854
C074702 chromium hexavalent ion STAT1 protein affects the susceptibility to chromium hexavalent ionaffects response to substance 19403854
D003474 Curcumin Curcumin inhibits the reaction [IFNG protein results in increased expression of and results in increased phosphorylation of STAT1 protein]decreases reaction|increases expression|increases phosphorylation 16959222
D003474 Curcumin Curcumin results in decreased expression of STAT1decreases expression 18462866
D003609 Dactinomycin Dactinomycin results in increased expression of STAT1 mRNAincreases expression 16001973
C004742 daidzein daidzein inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased activity of STAT1 protein alternative form]affects localization|decreases reaction|increases activity 18274639
C014347 decitabine [decitabine affects the methylation of STAT1 gene] which affects the expression of STAT1 mRNAaffects expression|affects methylation 18649362
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of STAT1 mRNAincreases expression 15766595
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of STAT1 mRNAincreases expression 17011747
D004128 Dimethylnitrosamine Dimethylnitrosamine results in decreased expression of STAT1 mRNAdecreases expression 14600272
D004317 Doxorubicin Doxorubicin results in increased expression of STAT1 mRNAincreases expression 16001973
D004317 Doxorubicin STAT1 protein results in decreased susceptibility to Doxorubicindecreases response to substance 17072862
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of STAT1 mRNAaffects cotreatment|increases expression 19619570
D004958 Estradiol Estradiol results in increased expression of STAT1 mRNAincreases expression 16514628
19619570
D000431 Ethanol Ethanol inhibits the reaction [IFNG protein results in increased activity of STAT1 protein]decreases reaction|increases activity 18166357
D000431 Ethanol [Fish Oils co-treated with Ethanol] results in increased expression of STAT1 mRNAaffects cotreatment|increases expression 17347304
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of STAT1 mRNAaffects expression 17555576
D005038 Ethylnitrosourea Ethylnitrosourea results in increased mutagenesis of STAT1 geneincreases mutagenesis 16724327
16688530
D005047 Etoposide [STAT1 protein results in increased activity of CASP3 protein] which results in increased susceptibility to Etoposideincreases activity|increases response to substance 18649362
D005047 Etoposide [STAT1 protein results in increased activity of CASP7 protein] which results in increased susceptibility to Etoposideincreases activity|increases response to substance 18649362
C020748 ferrous sulfate ferrous sulfate results in increased phosphorylation of STAT1 proteinincreases phosphorylation 17607690
D005395 Fish Oils [Fish Oils co-treated with Ethanol] results in increased expression of STAT1 mRNAaffects cotreatment|increases expression 17347304
D005419 Flavonoids Flavonoids results in decreased expression of STAT1 mRNAdecreases expression 15465739
D005419 Flavonoids Flavonoids results in decreased expression of STAT1 proteindecreases expression 15465739
C024352 fludarabine fludarabine results in decreased activity of STAT1 proteindecreases activity 17072862
D005485 Flutamide Flutamide results in decreased expression of STAT1 mRNAdecreases expression 11509743
C070081 fulvestrant fulvestrant results in decreased expression of STAT1 mRNAdecreases expression 16514628
D019833 Genistein Genistein inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased activity of STAT1 protein alternative form]affects localization|decreases reaction|increases activity 18274639
D005978 Glutathione Glutathione inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]decreases reaction|increases phosphorylation 12847270
D005978 Glutathione Glutathione promotes the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]increases phosphorylation|increases reaction 12847270
D006581 Hexachlorobenzene Hexachlorobenzene results in increased expression of STAT1 mRNAincreases expression 15159207
C029424 hydrazine hydrazine results in decreased expression of STAT1 mRNAdecreases expression 15282401
D006861 Hydrogen Peroxide Hydrogen Peroxide affects the reaction [vanadium pentoxide results in increased phosphorylation of and results in increased activity of STAT1 protein]affects reaction|increases activity|increases phosphorylation 18322232
D006861 Hydrogen Peroxide Hydrogen Peroxide inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT1 protein]decreases reaction|increases activity|increases phosphorylation 15748169
D006861 Hydrogen Peroxide Hydrogen Peroxide inhibits the reaction [IFNG protein affects the localization of STAT1 protein]affects localization|decreases reaction 15748169
D006861 Hydrogen Peroxide Hydrogen Peroxide inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of STAT1 protein]decreases reaction|increases activity|increases phosphorylation 15748169
D006861 Hydrogen Peroxide Hydrogen Peroxide inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 12847270
D006861 Hydrogen Peroxide Hydrogen Peroxide promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]decreases reaction|increases phosphorylation|increases reaction 12847270
D006861 Hydrogen Peroxide Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 17607690
D006861 Hydrogen Peroxide alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 17607690
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased phosphorylation of STAT1 proteinincreases phosphorylation 17607690
D007213 Indomethacin Indomethacin results in decreased expression of and results in decreased phosphorylation of STAT1 proteindecreases expression|decreases phosphorylation 16572323
D007213 Indomethacin Indomethacin results in decreased expression of STAT1 proteindecreases expression 15631656
D007213 Indomethacin Indomethacin results in decreased expression of STAT1 protein modified formdecreases expression 16572323
C051890 irinotecan irinotecan results in increased phosphorylation of STAT1 proteinincreases phosphorylation 16204068
C051890 irinotecan STAT1 protein promotes the reaction [irinotecan results in increased localization of FAS protein]increases localization|increases reaction 16204068
C051890 irinotecan TP53 protein inhibits the reaction [irinotecan results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 16204068
C006552 kaempferol kaempferol inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased activity of STAT1 protein alternative form]affects localization|decreases reaction|increases activity 18274639
D007657 Ketone Bodies Ketone Bodies results in decreased expression of STAT1 mRNAdecreases expression 16807920
C482199 lipopolysaccharide, E coli O55-B5 lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of STAT1 proteinincreases phosphorylation 17630198
D008070 Lipopolysaccharides daidzein inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased activity of STAT1 protein alternative form]affects localization|decreases reaction|increases activity 18274639
D008070 Lipopolysaccharides Genistein inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased activity of STAT1 protein alternative form]affects localization|decreases reaction|increases activity 18274639
D008070 Lipopolysaccharides IFNB1 protein affects the reaction [Lipopolysaccharides results in increased phosphorylation of STAT1 protein]affects reaction|increases phosphorylation 18323514
D008070 Lipopolysaccharides kaempferol inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased activity of STAT1 protein alternative form]affects localization|decreases reaction|increases activity 18274639
D008070 Lipopolysaccharides Lipopolysaccharides affects the localization of and results in increased activity of STAT1 protein alternative formaffects localization|increases activity 18274639
D008070 Lipopolysaccharides Lipopolysaccharides results in decreased expression of STAT1 mRNAdecreases expression 12057914
D008070 Lipopolysaccharides Lipopolysaccharides results in increased activity of and results in increased localization of STAT1 proteinincreases activity|increases localization 17891158
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of and results in increased phosphorylation of STAT1 proteinincreases expression|increases phosphorylation 20423518
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of STAT1 mRNAincreases expression 20423518
D008070 Lipopolysaccharides Lipopolysaccharides results in increased phosphorylation of STAT1 proteinincreases phosphorylation 18323514
D008070 Lipopolysaccharides phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased phosphorylation of STAT1 protein]decreases reaction|increases expression|increases phosphorylation 20423518
D008070 Lipopolysaccharides phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of STAT1 mRNA]decreases reaction|increases expression 20423518
D008070 Lipopolysaccharides pitavastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 18323514
D008070 Lipopolysaccharides Pravastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 18323514
D008070 Lipopolysaccharides Quercetin inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased activity of STAT1 protein alternative form]affects localization|decreases reaction|increases activity 18274639
D008464 Mecamylamine Mecamylamine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of STAT1 protein]decreases reaction|increases activity 16582591
D008464 Mecamylamine Mecamylamine inhibits the reaction [N'-nitrosonornicotine results in increased activity of STAT1 protein]decreases reaction|increases activity 16582591
D008464 Mecamylamine Mecamylamine inhibits the reaction [N'-nitrosonornicotine results in increased expression of STAT1 mRNA]decreases reaction|increases expression 16835749
D009151 Mustard Gas Mustard Gas results in increased expression of STAT1 mRNAincreases expression 18955075
D009532 Nickel STAT1 protein affects the reaction [chromium hexavalent ion inhibits the reaction [Nickel results in increased expression of VEGFA mRNA]]affects reaction|decreases reaction|increases expression 19403854
D009532 Nickel STAT1 protein affects the reaction [chromium hexavalent ion inhibits the reaction [Nickel results in increased stability of and results in increased expression of HIF1A protein]]affects reaction|decreases reaction|increases expression|increases stability 19403854
D009582 Nitrofurantoin Nitrofurantoin inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT1 protein]decreases reaction|increases activity|increases phosphorylation 15748169
D009582 Nitrofurantoin Rotenone promotes the reaction [Nitrofurantoin inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT1 protein]]decreases reaction|increases activity|increases phosphorylation|increases reaction 15748169
D009609 Nitrous Oxide Nitrous Oxide inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT1 protein]decreases reaction|increases activity|increases phosphorylation 15748169
C008655 N'-nitrosonornicotine Bungarotoxins inhibits the reaction [N'-nitrosonornicotine results in increased activity of STAT1 protein]decreases reaction|increases activity 16582591
C008655 N'-nitrosonornicotine Mecamylamine inhibits the reaction [N'-nitrosonornicotine results in increased activity of STAT1 protein]decreases reaction|increases activity 16582591
C008655 N'-nitrosonornicotine Mecamylamine inhibits the reaction [N'-nitrosonornicotine results in increased expression of STAT1 mRNA]decreases reaction|increases expression 16835749
C008655 N'-nitrosonornicotine N'-nitrosonornicotine results in increased activity of STAT1 proteinincreases activity 16582591
C008655 N'-nitrosonornicotine N'-nitrosonornicotine results in increased expression of STAT1 mRNAincreases expression 16582591
16835749
C069741 norcantharidin norcantharidin results in increased expression of STAT1 proteinincreases expression 19616522
D053683 Oncostatin M Oncostatin M results in increased phosphorylation of STAT1 proteinincreases phosphorylation 15654950
D010126 Ozone Acetylcysteine inhibits the reaction [Ozone results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 19061877
D010126 Ozone alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Ozone results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 19061877
D010126 Ozone Ozone results in increased phosphorylation of STAT1 proteinincreases phosphorylation 19061877
D010126 Ozone pimagedine inhibits the reaction [Ozone results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 19061877
D010126 Ozone zinc protoporphyrin inhibits the reaction [Ozone results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 19061877
D010126 Ozone Ozone results in increased expression of and results in increased activity of STAT1 proteinincreases activity|increases expression 12162464
C500599 peroxyvanadate 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [peroxyvanadate results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 12847270
C500599 peroxyvanadate peroxyvanadate inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]decreases reaction|increases phosphorylation 12847270
C500599 peroxyvanadate peroxyvanadate promotes the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]increases phosphorylation|increases reaction 12847270
C500599 peroxyvanadate peroxyvanadate results in increased phosphorylation of STAT1 proteinincreases phosphorylation 12847270
C058305 phenethyl isothiocyanate phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased phosphorylation of STAT1 protein]decreases reaction|increases expression|increases phosphorylation 20423518
C058305 phenethyl isothiocyanate phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of STAT1 mRNA]decreases reaction|increases expression 20423518
D010656 Phenylephrine Phenylephrine results in decreased expression of STAT1 mRNAdecreases expression 18158353
D010712 Phosphatidic Acids Phosphatidic Acids results in increased phosphorylation of and affects the localization of STAT1 proteinaffects localization|increases phosphorylation 16354768
C004479 pimagedine pimagedine inhibits the reaction [Ozone results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 19061877
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of STAT1 mRNAaffects binding|increases activity|increases expression 19710929
C006253 pirinixic acid pirinixic acid results in decreased expression of STAT1 mRNAdecreases expression 17426115
C108475 pitavastatin pitavastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 18323514
D010936 Plant Extracts Plant Extracts results in decreased expression of STAT1 mRNAdecreases expression 15465739
D010936 Plant Extracts Plant Extracts results in decreased expression of STAT1 proteindecreases expression 15465739
D028321 Plant Preparations Plant Preparations affects the expression of STAT1 mRNAaffects expression 16046712
C025299 polyphenols polyphenols results in decreased expression of STAT1 mRNAdecreases expression 15465739
C025299 polyphenols polyphenols results in decreased expression of STAT1 proteindecreases expression 15465739
D011192 Potassium Dichromate Potassium Dichromate results in increased phosphorylation of and affects the localization of STAT1 proteinaffects localization|increases phosphorylation 17078813
D017035 Pravastatin Pravastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 18323514
D011794 Quercetin Quercetin inhibits the reaction [STAT1 protein modified form binds to TRADD protein]affects binding|decreases reaction 16077199
D011794 Quercetin Quercetin results in decreased expression of STAT1 mRNAdecreases expression 15309432
D011794 Quercetin Quercetin results in decreased phosphorylation of STAT1 proteindecreases phosphorylation 16077199
D011794 Quercetin Quercetin inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 16171798
D011794 Quercetin Quercetin inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased activity of STAT1 protein alternative form]affects localization|decreases reaction|increases activity 18274639
D020849 Raloxifene Raloxifene results in decreased expression of STAT1 mRNAdecreases expression 16514628
C068874 raltitrexed raltitrexed results in increased phosphorylation of STAT1 proteinincreases phosphorylation 16204068
C068874 raltitrexed STAT1 protein promotes the reaction [raltitrexed results in increased localization of FAS protein]increases localization|increases reaction 16204068
C068874 raltitrexed TP53 protein inhibits the reaction [raltitrexed results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 16204068
C084904 Ro 41-5253 Ro 41-5253 inhibits the reaction [Am 580 results in increased phosphorylation of and results in increased activity of STAT1 protein]decreases reaction|increases activity|increases phosphorylation 16085646
C084904 Ro 41-5253 Ro 41-5253 inhibits the reaction [Tretinoin results in increased phosphorylation of and results in increased activity of STAT1 protein]decreases reaction|increases activity|increases phosphorylation 16085646
C084904 Ro 41-5253 Ro 41-5253 results in decreased expression of STAT1 proteindecreases expression 16007204
D012402 Rotenone Rotenone inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT1 protein]decreases reaction|increases activity|increases phosphorylation 15748169
D012402 Rotenone Rotenone inhibits the reaction [IFNG protein affects the localization of STAT1 protein]affects localization|decreases reaction 15748169
D012402 Rotenone Rotenone inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of STAT1 protein]decreases reaction|increases activity|increases phosphorylation 15748169
D012402 Rotenone Rotenone promotes the reaction [Nitrofurantoin inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT1 protein]]decreases reaction|increases activity|increases phosphorylation|increases reaction 15748169
C009277 sodium arsenate sodium arsenate results in increased expression of STAT1 mRNAincreases expression 16882884
C017947 sodium arsenite sodium arsenite results in increased phosphorylation of STAT1 proteinincreases phosphorylation 19168569
D014284 Triiodothyronine Triiodothyronine inhibits the reaction [FGF2 protein results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 16150908
D013629 Tamoxifen Tamoxifen results in increased expression of STAT1 mRNAincreases expression 19155303
D013629 Tamoxifen Tamoxifen affects the expression of STAT1 mRNAaffects expression 17555576
C003377 taxifolin taxifolin inhibits the reaction [IFNG protein results in increased activity of and results in increased localization of STAT1 protein]decreases reaction|increases activity|increases localization 12044887
C004648 testosterone enanthate testosterone enanthate affects the expression of STAT1 mRNAaffects expression 17440010
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of STAT1 mRNAaffects cotreatment|increases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of STAT1 mRNAdecreases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of STAT1 mRNAincreases expression 12377990
16704738
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of STAT1 mRNAincreases expression 14708085
D013876 Thiophenes Thiophenes analog promotes the reaction [Tretinoin results in increased expression of STAT1 mRNA]increases expression|increases reaction 16140955
D014212 Tretinoin Ro 41-5253 inhibits the reaction [Tretinoin results in increased phosphorylation of and results in increased activity of STAT1 protein]decreases reaction|increases activity|increases phosphorylation 16085646
D014212 Tretinoin STAT1 protein affects the reaction [Tretinoin results in increased expression of CEBPE protein]affects reaction|increases expression 16918696
D014212 Tretinoin STAT1 protein affects the reaction [Tretinoin results in increased expression of IRF8 protein]affects reaction|increases expression 16918696
D014212 Tretinoin STAT1 protein affects the reaction [Tretinoin results in increased expression of STAT2 protein]affects reaction|increases expression 16918696
D014212 Tretinoin STAT1 protein promotes the reaction [Tretinoin results in increased expression of CLIP1 mRNA]increases expression|increases reaction 16574066
D014212 Tretinoin Thiophenes analog promotes the reaction [Tretinoin results in increased expression of STAT1 mRNA]increases expression|increases reaction 16140955
D014212 Tretinoin Tretinoin inhibits the reaction [IFNG protein results in increased expression of STAT1 protein]decreases reaction|increases expression 16007204
D014212 Tretinoin Tretinoin inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 16636311
D014212 Tretinoin Tretinoin promotes the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of STAT1 protein]increases activity|increases phosphorylation|increases reaction 16085646
D014212 Tretinoin Tretinoin results in decreased expression of STAT1 proteindecreases expression 16007204
D014212 Tretinoin Tretinoin results in increased expression of STAT1 mRNAincreases expression 16140955
D014212 Tretinoin Tretinoin results in increased phosphorylation of and results in increased activity of STAT1 proteinincreases activity|increases phosphorylation 16085646
D014302 Trinitrobenzenesulfonic Acid Trinitrobenzenesulfonic Acid results in increased expression of STAT1 mRNAincreases expression 17982090
C081489 valsartan valsartan inhibits the reaction [AGT protein affects the localization of STAT1 protein]affects localization|decreases reaction 12846741
C081489 valsartan valsartan inhibits the reaction [AGT protein results in increased activity of STAT1 protein]decreases reaction|increases activity 12846741
C081489 valsartan valsartan inhibits the reaction [AGT protein results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 12846741
C066075 vanadium pentoxide acetovanillone inhibits the reaction [vanadium pentoxide results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 18322232
C066075 vanadium pentoxide Allopurinol inhibits the reaction [vanadium pentoxide results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 18322232
C066075 vanadium pentoxide Hydrogen Peroxide affects the reaction [vanadium pentoxide results in increased phosphorylation of and results in increased activity of STAT1 protein]affects reaction|increases activity|increases phosphorylation 18322232
C066075 vanadium pentoxide IFNB1 protein affects the reaction [vanadium pentoxide results in increased activity of STAT1 protein]affects reaction|increases activity 18322232
C066075 vanadium pentoxide JAK1 protein affects the reaction [vanadium pentoxide results in increased activity of STAT1 protein]affects reaction|increases activity 18322232
C066075 vanadium pentoxide vanadium pentoxide results in decreased expression of STAT1 mRNAdecreases expression 17459161
C066075 vanadium pentoxide vanadium pentoxide results in increased activity of and results in increased phosphorylation of STAT1 proteinincreases activity|increases phosphorylation 18322232
C025643 vinclozolin vinclozolin affects the expression of STAT1 mRNAaffects expression 19015723
C025643 vinclozolin vinclozolin results in decreased expression of STAT1 mRNAdecreases expression 18042343
D014750 Vincristine Vincristine results in increased expression of STAT1 mRNAincreases expression 16001973
C017963 vinyl carbamate vinyl carbamate results in decreased expression of STAT1 mRNAdecreases expression 17849452
D014810 Vitamin E Vitamin E results in decreased expression of STAT1 mRNAdecreases expression 19244175
D015215 Zidovudine [Zidovudine co-treated with IFNA1 protein] results in increased expression of STAT1 mRNAaffects cotreatment|increases expression 20370541
C017803 zinc protoporphyrin zinc protoporphyrin inhibits the reaction [Ozone results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 19061877
D015054 Zymosan IL6 protein affects the reaction [Zymosan results in increased phosphorylation of and results in increased activity of STAT1 protein]affects reaction|increases activity|increases phosphorylation 15188379
D015054 Zymosan STAT1 protein affects the reaction [Zymosan results in increased expression of SOCS1 mRNA]affects reaction|increases expression 15188379
D015054 Zymosan STAT1 protein affects the susceptibility to Zymosanaffects response to substance 15188379
D015054 Zymosan Zymosan results in increased phosphorylation of and results in increased activity of STAT1 proteinincreases activity|increases phosphorylation 15188379
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 3.6414745880
MESH:D000014 Abnormalities, Drug-Induced Ethanol 5.5818926900 17676605
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 5.5815322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 7.5418287403
MESH:D000138 Acidosis Ethanol 7.5411192467
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.0417505938
MESH:D000163 Acquired Immunodeficiency Syndrome Zidovudine 3.969612607
MESH:D055371 Acute Lung Injury Lipopolysaccharides 10.6118653653 11850527
MESH:D055371 Acute Lung Injury Nickel 10.6116166738
MESH:D055371 Acute Lung Injury pirinixic acid 10.6118653653
MESH:D000230 Adenocarcinoma arsenic trioxide 28.7519825857 11798837
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 28.7520464547 20127859
MESH:D000230 Adenocarcinoma daidzein 28.7511473722
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 28.7516033868
MESH:D000230 Adenocarcinoma Doxorubicin 28.7517418594
MESH:D000230 Adenocarcinoma Estradiol 28.7511473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 28.7514692618
MESH:D000230 Adenocarcinoma Genistein 28.7511473722
MESH:D000230 Adenocarcinoma Indomethacin 28.7516537180
MESH:D000230 Adenocarcinoma Vincristine 28.7519825857
MESH:D000230 Adenocarcinoma vinyl carbamate 28.7517363558 16247444
MESH:D000236 Adenoma 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 14.7416176798
MESH:D000236 Adenoma Benzo(a)pyrene 14.746695378
MESH:D000236 Adenoma Dimethylnitrosamine 14.7419555203
MESH:D000236 Adenoma Ethylnitrosourea 14.746695378
MESH:D000236 Adenoma Indomethacin 14.7411497255
MESH:D018248 Adenoma, Liver Cell pirinixic acid 12.4216434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 12.4216835633
MESH:D018248 Adenoma, Liver Cell vinyl carbamate 12.4212371669
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 3.8015276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.0017306315 16712894
MESH:D000419 Albuminuria Doxorubicin 8.6421441931
MESH:D000419 Albuminuria Raloxifene 8.6417308373 17451421
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.4115451039 15451040
MESH:D000437 Alcoholism Mecamylamine 4.9220201817
MESH:D019973 Alcohol-Related Disorders Curcumin 4.1817887948
MESH:D000505 Alopecia Tretinoin 2.8815955085
MESH:D016301 Alveolar Bone Loss Indomethacin 4.4717225004
MESH:D000544 Alzheimer Disease Curcumin 9.1615590663
MESH:D000544 Alzheimer Disease Indomethacin 9.1617627676 15579461
MESH:D000544 Alzheimer Disease Ozone 9.1615513908
MESH:D000544 Alzheimer Disease Plant Extracts 9.1616962711
MESH:D000544 Alzheimer Disease Raloxifene 9.1615800139
MESH:D000686 Amyloidosis Diethylstilbestrol 3.6315469931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 6.3811748828
MESH:D000740 Anemia Zymosan 6.3818664788
MESH:D000741 Anemia, Aplastic Benzene 3.6417661222 11369114 14761424
MESH:D000743 Anemia, Hemolytic Quercetin 3.4317084956
MESH:D000853 Anophthalmos Ethanol 3.9515513904
MESH:D001008 Anxiety Disorders Ethanol 6.5611141031
MESH:D001008 Anxiety Disorders vinclozolin 6.5619015723
MESH:D001014 Aortic Aneurysm Indomethacin 4.0010231640
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 8.8319183758
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 8.8310388637
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 3.3317460149
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 2.6011256880
MESH:D018771 Arthralgia Indomethacin 4.272160914
MESH:D001169 Arthritis, Experimental marker/mechanism 15188379
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 12.4815885639
MESH:D001169 Arthritis, Experimental Plant Extracts 12.4814686799
MESH:D001169 Arthritis, Experimental Tretinoin 12.4816412693
MESH:D001169 Arthritis, Experimental Zymosan 12.4815188379 15944321 15142272 17659584 16872482
MESH:D001172 Arthritis, Rheumatoid Curcumin 7.8916807698
MESH:D001172 Arthritis, Rheumatoid Indomethacin 7.8911248219
MESH:D001172 Arthritis, Rheumatoid Ozone 7.8915570426
MESH:D001172 Arthritis, Rheumatoid Tretinoin 7.8916292516
MESH:D001249 Asthma Mustard Gas 5.6910378619
MESH:D001249 Asthma Ozone 5.6916373670 17854713
MESH:D001249 Asthma Tretinoin 5.6916456186
MESH:D001260 Ataxia Telangiectasia Quercetin 4.0915336622
MESH:D050197 Atherosclerosis Cadmium 5.0515687053
MESH:D050197 Atherosclerosis Curcumin 5.0518704882
MESH:D001284 Atrophy fulvestrant 4.0011514358
MESH:D001321 Autistic Disorder Glutathione 3.2118929414 16917939 19267885 19056591
MESH:D001327 Autoimmune Diseases Curcumin 7.9919761891
MESH:D001327 Autoimmune Diseases Quercetin 7.9919761891
MESH:D001471 Barrett Esophagus Tretinoin 3.5516935849
MESH:D001477 Bartter Syndrome Indomethacin 4.1110684365
MESH:D001768 Blister Mustard Gas 4.2719167455
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 20.3616206674
MESH:D001778 Blood Coagulation Disorders ferrous sulfate 20.366421970
MESH:D001778 Blood Coagulation Disorders pirinixic acid 20.3619483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 20.3612125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 20.3616206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 2.8915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.1315746008
MESH:D001855 Bone Marrow Diseases Benzene 4.3316183116
MESH:D019046 Bone Marrow Neoplasms Dactinomycin 15.2714601052
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 15.2714601052
MESH:D019046 Bone Marrow Neoplasms Etoposide 15.2714601052
MESH:D001919 Bradycardia Phenylephrine 3.6615306635
MESH:D001927 Brain Diseases Ethylnitrosourea 4.0914991843
MESH:D001929 Brain Edema Indomethacin 4.1211481608
MESH:D001930 Brain Injuries Raloxifene 3.6116580743
MESH:D002545 Brain Ischemia Curcumin 12.0816770732
MESH:D002545 Brain Ischemia Indomethacin 12.0812524144
MESH:D002545 Brain Ischemia Plant Extracts 12.0816041641
MESH:D001932 Brain Neoplasms Curcumin 10.2417596214
MESH:D001932 Brain Neoplasms Doxorubicin 10.2417150277
MESH:D001932 Brain Neoplasms Ethylnitrosourea 10.2416436596 16357521 18412241 15144691 16651633
MESH:D001943 Breast Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 22.3920146248
MESH:D001943 Breast Neoplasms alitretinoin 22.3916344269
MESH:D001943 Breast Neoplasms Benzene 22.3917162533 11921183
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 22.3920146248 17474063
MESH:D001943 Breast Neoplasms Curcumin 22.3918593918 19250217 18462866 16243823
MESH:D001943 Breast Neoplasms decitabine 22.3918320071 19208741
MESH:D001943 Breast Neoplasms Diethylstilbestrol 22.3917129689 15324884
MESH:D001943 Breast Neoplasms Doxorubicin 22.3916595493 18382427 16826403 15939500 17983394 18695136 17369602 16264153 15634643 15567936 15692762 15136595 18628466 16096432 15994142 17426702 11325840 15993339 16322301 15668708 18234424 19526202 16115903 16935488
MESH:D001943 Breast Neoplasms Estradiol 22.3912948864 17289903 19861407 16675129 18497071 17018787 17261762 14630087
MESH:D001943 Breast Neoplasms Etoposide 22.3916322251
MESH:D001943 Breast Neoplasms fulvestrant 22.3918984771
MESH:D001943 Breast Neoplasms Genistein 22.3916541309 16873071 17200150
MESH:D001943 Breast Neoplasms Hexachlorobenzene 22.3912709520 15061365
MESH:D001943 Breast Neoplasms Indomethacin 22.3917401462
MESH:D001943 Breast Neoplasms kaempferol 22.3916756079
MESH:D001943 Breast Neoplasms Nickel 22.3915986119
MESH:D001943 Breast Neoplasms Plant Preparations 22.3917398067
MESH:D001943 Breast Neoplasms Quercetin 22.3918628248
MESH:D001943 Breast Neoplasms Raloxifene 22.3916912660 15572757 15775269 17952589 17242785 17261762 17440819 16837676 15758505 17595753 17893378 17049068
MESH:D001943 Breast Neoplasms Tamoxifen 22.3918997820 19487384 16818667 19189210 18984771 16873071 18351453 19115204 20135344 19084267 20859285 15668708 17242785 18629630 16273361 19200415 20005174 19189212 19155303 20390343 19066611 19410462 19289846 21152245 11161223 19288272 19103187 17261762 18425577 15565566 19244106 18855134 20065188 17893378 18821012 17049068 19059307 18815881 21138602 19142967 19221464 20544844 16202921 17440819 19011961
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 22.3920435547
MESH:D001943 Breast Neoplasms Tretinoin 22.3916873071 16166294 16443354
MESH:D016535 Bronchial Hyperreactivity Ozone 2.9515516495 17626835 18417511 19059883 18315731 14754758 16777450
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.2715286001
MESH:D001991 Bronchitis vanadium pentoxide 5.3317459161
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.0717687719 10378619
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 3.7016813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.5011589617
MESH:D002056 Burns Ethanol 8.5016374292
MESH:D002056 Burns Indomethacin 8.5010459503
MESH:D002057 Burns, Chemical Plant Extracts 4.439625245
MESH:D002100 Cachexia Indomethacin 9.4611239499 15625704 15141370 16537180
MESH:D002100 Cachexia Ozone 9.4616183385
MESH:D002105 Cadmium Poisoning Quercetin 4.6416962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.5716111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 7.0715700767 16124888 15721981 16011737 16192424 18705752 3786805 16097048 10355542 15673190 16050911 16227642
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 7.0716050911
MESH:D002276 Carcinoid Tumor Doxorubicin 3.9116051944
MESH:D002277 Carcinoma Curcumin 9.7818593918
MESH:D002277 Carcinoma Dimethylnitrosamine 9.7819555203
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 9.7816835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 3.6319066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.2516168501
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 34.5016705839
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 34.5021507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 34.5014691202 15073043 11135700 15553829 16217749
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 34.5018788625
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 34.5015948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 34.5016234567 16023760 18059187 17876044
MESH:D006528 Carcinoma, Hepatocellular Estradiol 34.5016924424
MESH:D006528 Carcinoma, Hepatocellular Ethanol 34.5018788625 15763234 15289165
MESH:D006528 Carcinoma, Hepatocellular Genistein 34.5016924424
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 34.5016391822
MESH:D006528 Carcinoma, Hepatocellular Plant Extracts 34.5018834353
MESH:D006528 Carcinoma, Hepatocellular Quercetin 34.5019519916 12508355
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 34.5016507464 15276417 17306315
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 34.5016924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 34.501917145
MESH:D006528 Carcinoma, Hepatocellular vinyl carbamate 34.5012371669
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 3.8411053908
MESH:D018276 Carcinoma, Medullary Indomethacin 4.4618791128 14736730 11352223
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 4.8118414057
MESH:D002289 Carcinoma, Non-Small-Cell Lung vinyl carbamate 4.8116247446
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.0817234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 3.9719014326
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 8.0416201981 1485588
MESH:D002292 Carcinoma, Renal Cell Indomethacin 8.0417341418
MESH:D002292 Carcinoma, Renal Cell Vincristine 8.0416201981
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.3212490120
MESH:D002294 Carcinoma, Squamous Cell Acetylcysteine 33.4117015178
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 33.4120419170
MESH:D002294 Carcinoma, Squamous Cell Curcumin 33.4118462866
MESH:D002294 Carcinoma, Squamous Cell decitabine 33.4119215824
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 33.4116033868
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 33.416189445
MESH:D002294 Carcinoma, Squamous Cell Glutathione 33.4117015178
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 33.4112636206 15482327
MESH:D002294 Carcinoma, Squamous Cell Plant Preparations 33.4117418620
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 33.4118572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 33.4116051514 16096774
MESH:D002294 Carcinoma, Squamous Cell Vincristine 33.416189445
MESH:D002295 Carcinoma, Transitional Cell Nitrofurantoin 11.5515028437
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 11.5517572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 11.5517572228
MESH:D006332 Cardiomegaly Ethanol 19.3119332462
MESH:D006332 Cardiomegaly Phenylephrine 19.3115728586 11179087 11754973 17124262 17287366 16170337
MESH:D006332 Cardiomegaly Plant Extracts 19.3117645561
MESH:D006332 Cardiomegaly Quercetin 19.3119794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 19.3118670907 16120746 18850075
MESH:D006332 Cardiomegaly valsartan 19.3119597038
MESH:D009202 Cardiomyopathies Doxorubicin 9.5916455267 15476868 17131338 16952015 15811867 17519947 16364871 16651473 15792986 17924179 16612575 15505089 16242529 16109756 17007740 17308081 17928571 18627295 16731534 17351982 17329180 16278810 16269455 17382496 17974986
MESH:D009202 Cardiomyopathies pimagedine 9.5916612575
MESH:D009202 Cardiomyopathies valsartan 9.5916247790
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.5517334414 16243910
MESH:D002318 Cardiovascular Diseases daidzein 23.9516332659
MESH:D002318 Cardiovascular Diseases Genistein 23.9516332659
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 23.9516936243
MESH:D002318 Cardiovascular Diseases kaempferol 23.9516756079
MESH:D002318 Cardiovascular Diseases Plant Preparations 23.9516862667
MESH:D002318 Cardiovascular Diseases Raloxifene 23.9515775269
MESH:D002318 Cardiovascular Diseases valsartan 23.9511230374
MESH:D016893 Carotid Stenosis Plant Preparations 5.2515158307
MESH:D002386 Cataract Am 580 9.2617460283
MESH:D002386 Cataract pimagedine 9.2615003327 17936468
MESH:D002386 Cataract Tretinoin 9.2617460283
MESH:D002471 Cell Transformation, Neoplastic Acetylcysteine 14.1118226522
MESH:D002471 Cell Transformation, Neoplastic Cadmium 14.1117332340
MESH:D002471 Cell Transformation, Neoplastic Estradiol 14.1118566989
MESH:D002471 Cell Transformation, Neoplastic Ethylnitrosourea 14.1116003739
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 14.1119524636 20056578
MESH:D016543 Central Nervous System Neoplasms Ethylnitrosourea 5.0817160924
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 3.7016129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.3916835633
MESH:D002764 Cholecystitis Indomethacin 4.2711181007
MESH:D002779 Cholestasis Ethinyl Estradiol 5.4115861022 16919318 17333356 17681005 17110522 16105132 11677210
MESH:D002779 Cholestasis pirinixic acid 5.4119176532
MESH:D002822 Choriocarcinoma Tretinoin 4.2516461808
MESH:D002971 Cleft Lip Ethanol 3.0315513904
MESH:D002972 Cleft Palate Ethanol 7.0515513904
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 7.0515668235 8697196 12621046 16354765 15340226
MESH:D002972 Cleft Palate Tretinoin 7.059407595
MESH:D003072 Cognition Disorders Raloxifene 3.7515800139
MESH:D003092 Colitis Am 580 15.9017035595
MESH:D003092 Colitis Curcumin 15.9016804969 18200517 16782535
MESH:D003092 Colitis Tretinoin 15.9017035595
MESH:D003092 Colitis Trinitrobenzenesulfonic Acid 15.9017991707 11698051 18023891 17936198 16867261 16782535 16804969 18200517 16474422
MESH:D003093 Colitis, Ulcerative phenethyl isothiocyanate 5.0720423518
MESH:D003093 Colitis, Ulcerative Trinitrobenzenesulfonic Acid 5.0717276891
MESH:D003103 Coloboma Curcumin 3.7418809619
MESH:D003110 Colonic Neoplasms arsenite 15.6715037631
MESH:D003110 Colonic Neoplasms Curcumin 15.6716340194 19359593
MESH:D003110 Colonic Neoplasms decitabine 15.6717616700
MESH:D003110 Colonic Neoplasms Genistein 15.6717182828
MESH:D003110 Colonic Neoplasms Indomethacin 15.6715637740 15786552 15936596 15963497 15625704 11260862
MESH:D003110 Colonic Neoplasms irinotecan 15.6717725105 17287894
MESH:D003110 Colonic Neoplasms polyphenols 15.6716293270
MESH:D003110 Colonic Neoplasms Quercetin 15.6719056647 11134977 17191121 15741050 17148506 19440933 16640504
MESH:D015179 Colorectal Neoplasms arsenic trioxide 6.3420501625
MESH:D015179 Colorectal Neoplasms decitabine 6.3418981723
MESH:D015179 Colorectal Neoplasms Doxorubicin 6.3418259882 18802399
MESH:D015179 Colorectal Neoplasms Indomethacin 6.3411197048 12606626 18059344 17054584
MESH:D015179 Colorectal Neoplasms irinotecan 6.3416391804 17159606 17454858 18259882 15273666 18509181 16303861
MESH:D015179 Colorectal Neoplasms Quercetin 6.3418852136 18095365
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.2917141729 14669216
MESH:D016510 Corneal Neovascularization Curcumin 4.0318497527
MESH:D003324 Coronary Artery Disease Plant Preparations 5.4215158307
MESH:D003324 Coronary Artery Disease valsartan 5.4217719468
MESH:D023903 Coronary Restenosis arsenic trioxide 3.3412609071
MESH:D018352 Coronavirus Infections Indomethacin 4.8117302372
MESH:D003384 Coxsackievirus Infections valsartan 4.9520392896
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 9.0210525206
MESH:D019465 Craniofacial Abnormalities Benzene 9.0215643154
MESH:D019465 Craniofacial Abnormalities Ethanol 9.0219302082 15513904 15451039 15451040 11198716 11873399 10194807
MESH:D019465 Craniofacial Abnormalities sodium arsenate 9.0210525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 9.0210048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 9.028800419 16925845 9125849 9142499 9664655 14991402 9211117 17551590 9224671 10589399
MESH:D019465 Craniofacial Abnormalities Vitamin E 9.0219769572
MESH:D003456 Cryptorchidism Diethylstilbestrol 8.5512952375 16002989
MESH:D003456 Cryptorchidism vinclozolin 8.5514966744
MESH:D003490 Cyanosis 2,4-dinitrotoluene 3.1518551238
MESH:D003550 Cystic Fibrosis Acetylcysteine 6.6219747007
MESH:D003550 Cystic Fibrosis Glutathione 6.6219747007
MESH:D003586 Cytomegalovirus Infections marker/mechanism 16688530
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.2715213294
MESH:D003711 Demyelinating Diseases Tamoxifen 3.4919031437
MESH:D003865 Depressive Disorder, Major Raloxifene 3.3917474826
MESH:D003872 Dermatitis Benzene 3.9015902427
MESH:D017449 Dermatitis, Allergic Contact Nickel 5.0519470301 17100760 17244072
MESH:D017449 Dermatitis, Allergic Contact Potassium Dichromate 5.0516823706
MESH:D003876 Dermatitis, Atopic pirinixic acid 1.9218249437
MESH:D003877 Dermatitis, Contact Nickel 3.822952479
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 6.3719496084
MESH:D003921 Diabetes Mellitus, Experimental valsartan 6.3711508273
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 7.5418403477
MESH:D003924 Diabetes Mellitus, Type 2 daidzein 7.5416647724
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 7.5416647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 7.5417107852
MESH:D003928 Diabetic Nephropathies Curcumin 25.0618204486
MESH:D003928 Diabetic Nephropathies Estradiol 25.0619279558
MESH:D003928 Diabetic Nephropathies Plant Extracts 25.0619706694
MESH:D003928 Diabetic Nephropathies Raloxifene 25.0615920148 17451421 17308373
MESH:D003928 Diabetic Nephropathies Tamoxifen 25.0619279558
MESH:D003928 Diabetic Nephropathies valsartan 25.0611427623 18630688
MESH:D003967 Diarrhea Indomethacin 2.997907874 7237001
MESH:D004283 Dog Diseases Allopurinol 5.3710449224
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 21.1721346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetylcysteine 21.1711287661
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 21.176884620 9327722 15027814 16227642 7179309 6623471 10915739 3732212 3786805 19336974 15998439 7120509 10092053 7440962 15968718 2869522 19085960 11566570 4309450 16177239 21278145 17522070
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 21.178172417
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 21.1717416283
MESH:D056486 Drug-Induced Liver Injury Ethanol 21.1711566570
MESH:D056486 Drug-Induced Liver Injury Nitrofurantoin 21.1719789166 8373174 19214031 1551546
MESH:D056486 Drug-Induced Liver Injury polyphenols 21.1719370779
MESH:D056486 Drug-Induced Liver Injury sodium arsenate 21.1718186108
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 21.1720420201
MESH:D004362 Drug Toxicity Doxorubicin 13.9318602426
MESH:D004362 Drug Toxicity Plant Preparations 13.9311033412
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 13.9311462148
MESH:D004362 Drug Toxicity Zidovudine 13.9315040536
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 4.2618446180 18043480 16326151 17190690 16133044 12774134
MESH:D004381 Duodenal Ulcer Curcumin 6.6317351913
MESH:D004381 Duodenal Ulcer Indomethacin 6.6317045617 17329845 16699067 11535926 11991626 11595431 17202747 10671773 17351913 11595415 17151854
MESH:C538011 Eales disease Vitamin E 3.809068938
MESH:D004476 Ectodermal Dysplasia Ethylnitrosourea 5.0818357618
MESH:D004487 Edema Indomethacin 20.558273558 8985016 19703484 16100529 7990266 10653021 7907874
MESH:D004487 Edema Mustard Gas 20.5511428647 11428631 9260866 11402378
MESH:D004487 Edema pirinixic acid 20.5512083418
MESH:D004487 Edema Plant Extracts 20.5512787963
MESH:D004487 Edema Raloxifene 20.5515860553
MESH:D004487 Edema Tetrachlorodibenzodioxin 20.5512711302 11000095
MESH:D004487 Edema Zymosan 20.557907874
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 8.9516714409 18230668 15322242
MESH:D004489 Edema, Cardiac Tretinoin 8.9518230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental 15-deoxy-delta(12,14)-prostaglandin J2 15.1116844232
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 15.1112538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 15.1115845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 15.1119031437
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.2119294695
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 8.9516402032
MESH:D004714 Endometrial Hyperplasia Genistein 8.9516402032
MESH:D016889 Endometrial Neoplasms 4-hydroxytamoxifen 29.8519148513
MESH:D016889 Endometrial Neoplasms daidzein 29.8511473722
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 29.8515700306 16804899
MESH:D016889 Endometrial Neoplasms Doxorubicin 29.8517359293
MESH:D016889 Endometrial Neoplasms Estradiol 29.8519148513 18566989 11473722
MESH:D016889 Endometrial Neoplasms Genistein 29.8511473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 29.8519155303 16202921 17893378 20544844
MESH:D016889 Endometrial Neoplasms Tretinoin 29.8516569247
MESH:D004715 Endometriosis Indomethacin 6.4515652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 6.4510568697 9294722
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 11.0618037988
MESH:D004719 Endomyocardial Fibrosis Plant Extracts 11.0615268973
MESH:D019446 Endotoxemia Indomethacin 7.7218509659
MESH:D019446 Endotoxemia Lipopolysaccharides 7.7217637181 15328337 15821434
MESH:D004751 Enteritis Indomethacin 3.8517763956 10567023 16328016
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 4.1117980183
MESH:D004802 Eosinophilia Indomethacin 3.2111298111
MESH:D004827 Epilepsy Plant Extracts 3.2019439326 19700373
MESH:D007172 Erectile Dysfunction daidzein 4.1714972507
MESH:D004890 Erythema Mustard Gas 4.279357497
MESH:D004938 Esophageal Neoplasms arsenic trioxide 12.9512903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 12.9516530937
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 12.9517016578
MESH:D004938 Esophageal Neoplasms Ethanol 12.9516704527
MESH:D004938 Esophageal Neoplasms Indomethacin 12.9511005569
MESH:D004938 Esophageal Neoplasms Plant Preparations 12.9516510608
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 6.4811564622
MESH:D005124 Eye Abnormalities Tretinoin 6.4816938888 9664655
MESH:D005234 Fatty Liver arsenic trioxide 49.0415073043
MESH:D005234 Fatty Liver arsenite 49.0418296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 49.0416239168 61145 12631006 19224547 17595544 16045604 15959796 12795759
MESH:D005234 Fatty Liver Curcumin 49.0419297423
MESH:D005234 Fatty Liver Ethanol 49.0418620774 19236843 16409862
MESH:D005234 Fatty Liver Ethinyl Estradiol 49.0415345470
MESH:D005234 Fatty Liver Fish Oils 49.0418620774
MESH:D005234 Fatty Liver pirinixic acid 49.0419236843 20131406
MESH:D005234 Fatty Liver Plant Extracts 49.0415975614
MESH:D005234 Fatty Liver Raloxifene 49.0417473493
MESH:D005234 Fatty Liver Tamoxifen 49.0414986274 19224547
MESH:D005234 Fatty Liver Zidovudine 49.0418299183
MESH:D005235 Fatty Liver, Alcoholic Ethanol 4.7617920746
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 6.1516611131 16513791 16534752 15751030 16002989
MESH:D052776 Female Urogenital Diseases Tamoxifen 6.1516709447
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.4116946407 15451040 10194807 15513904
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.5911858732
MESH:D005334 Fever Indomethacin 6.7417627676 10431976 11852909
MESH:D005334 Fever Lipopolysaccharides 6.7411852909 9205823
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 3.6414745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 8.5019069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 8.5019069698
MESH:D005354 Fibrosarcoma Indomethacin 4.0110962813
MESH:D005355 Fibrosis arsenite 38.9318296743
MESH:D005355 Fibrosis Carbon Tetrachloride 38.9318705752
MESH:D005355 Fibrosis Curcumin 38.9318705752
MESH:D005355 Fibrosis Indomethacin 38.9317994277
MESH:D005355 Fibrosis Quercetin 38.9319474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 38.9320067830
MESH:D005355 Fibrosis Tretinoin 38.9317994277
MESH:D005355 Fibrosis Trinitrobenzenesulfonic Acid 38.9317994277
MESH:D005355 Fibrosis valsartan 38.9316893502
MESH:D005499 Folliculitis Indomethacin 4.2711298111
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 9.2016904648
MESH:D005706 Gallbladder Neoplasms norcantharidin 9.2016681930
MESH:D005756 Gastritis Ethanol 8.5315046732
MESH:D005756 Gastritis Indomethacin 8.5315046732
MESH:D005770 Gastrointestinal Neoplasms Curcumin 3.8318462866
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.0416973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.3916417039
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 9.8716452187
MESH:D005833 Genital Neoplasms, Female sodium arsenite 9.8716452187
MESH:D005909 Glioblastoma Curcumin 23.6417596214
MESH:D005909 Glioblastoma Doxorubicin 23.6417150277
MESH:D005909 Glioblastoma Ethylnitrosourea 23.6416436596
MESH:D005909 Glioblastoma Genistein 23.6416598420
MESH:D005909 Glioblastoma Indomethacin 23.6412870263
MESH:D005909 Glioblastoma Quercetin 23.6419804834
MESH:D005909 Glioblastoma Tretinoin 23.6417312396
MESH:D005910 Glioma Ethylnitrosourea 7.3916651633 16357521 18412241
MESH:D005910 Glioma Indomethacin 7.3916487511 18371953
MESH:D005910 Glioma Quercetin 7.3917643826
MESH:D015432 Glomerulonephritis, Membranoproliferative valsartan 4.6916928621
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 3.5411849393
MESH:D018149 Glucose Intolerance sodium arsenate 4.2519446573
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.6910696789
MESH:D006073 Gout Indomethacin 4.4611248219
MESH:D006258 Head and Neck Neoplasms Curcumin 17.2318829502 18462866
MESH:D006258 Head and Neck Neoplasms decitabine 17.2319215824
MESH:D006258 Head and Neck Neoplasms Doxorubicin 17.2315692506
MESH:D006258 Head and Neck Neoplasms Indomethacin 17.2315482327
MESH:D006258 Head and Neck Neoplasms Tretinoin 17.2316096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.2516084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 11.3520471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 11.3511294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 11.3514991402 9664655
MESH:D006330 Heart Defects, Congenital Vitamin E 11.3516080930
MESH:D006331 Heart Diseases Doxorubicin 5.6116879835 16330681 17875725 14766674 18006777 16707910 16244372 18674790 16495754 12587719 17888722 16144979 16244371
MESH:D006331 Heart Diseases Raloxifene 5.6111110106
MESH:D006333 Heart Failure Doxorubicin 15.6717481944
MESH:D006333 Heart Failure pirinixic acid 15.6720558911
MESH:D006333 Heart Failure pitavastatin 15.6715502390
MESH:D006333 Heart Failure Plant Extracts 15.6718097624
MESH:D006333 Heart Failure valsartan 15.6719027736
MESH:D006394 Hemangiosarcoma Doxorubicin 3.1015692506
MESH:D006402 Hematologic Diseases Benzene 8.3316183116
MESH:D006402 Hematologic Diseases Zidovudine 8.3312579204
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 3.5916366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.5311000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 3.7615633222
MESH:D006505 Hepatitis Carbon Tetrachloride 6.8619110552 19900420
MESH:D006505 Hepatitis Zymosan 6.8619110552
MESH:D019698 Hepatitis C, Chronic Indomethacin 3.8315135802
MESH:D006521 Hepatitis, Chronic Nitrofurantoin 5.0714986274
MESH:D006529 Hepatomegaly pirinixic acid 5.4218467677 19772884 16221962 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 5.4212621046 15340226 16120746
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.1717701891
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.3016863852 16490937
MESH:D006558 Herpes Genitalis Estradiol 4.1315709030
MESH:D006561 Herpes Simplex Etoposide 7.3410809021
MESH:D006561 Herpes Simplex Plant Extracts 7.3410715843
MESH:D015658 HIV Infections Nickel 7.8117263646
MESH:D015658 HIV Infections Plant Extracts 7.8112878215
MESH:D015658 HIV Infections Zidovudine 7.8111141242 11698656 11363243 20032539 17358032
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 4.8417440010
MESH:D006689 Hodgkin Disease Doxorubicin 11.3618501091 17606976 15147373
MESH:D006689 Hodgkin Disease Etoposide 11.3618180244 16135485 16200630 17606976 15147373
MESH:D006689 Hodgkin Disease sodium arsenite 11.3612676792
MESH:D006689 Hodgkin Disease Vincristine 11.3616135485 17606976 16794504 15147373
MESH:D019584 Hot Flashes Estradiol 11.9617088409
MESH:D019584 Hot Flashes Plant Extracts 11.9616566672 14716179 17454163
MESH:D019584 Hot Flashes Vitamin E 11.9614716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.1416354765 15340226 16959395 18606429 8697196
MESH:D006930 Hyperalgesia Ethanol 8.9818783367
MESH:D006930 Hyperalgesia Indomethacin 8.9812727271
MESH:D006930 Hyperalgesia Tretinoin 8.9816870215
MESH:D034321 Hyperamylasemia Indomethacin 4.8117883296
MESH:D017588 Hyperandrogenism Flutamide 4.5615356085
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.6416899240
MESH:D006937 Hypercholesterolemia Curcumin 7.2118704882
MESH:D006937 Hypercholesterolemia Pravastatin 7.2117188708
MESH:D006940 Hyperemia Indomethacin 4.1212524144
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 3.7016778211
MESH:D006943 Hyperglycemia kaempferol 11.2518262572
MESH:D006943 Hyperglycemia pirinixic acid 11.2520558911
MESH:D006943 Hyperglycemia Quercetin 11.2511834736 18262572
MESH:D020138 Hyperhomocysteinemia Catechin 7.3617292331
MESH:D020138 Hyperhomocysteinemia Plant Extracts 7.3616484555
MESH:D006949 Hyperlipidemias Fish Oils 10.9715752949
MESH:D006949 Hyperlipidemias Indomethacin 10.9717546600
MESH:D006949 Hyperlipidemias Plant Extracts 10.9715975614 15268973
MESH:D006965 Hyperplasia Diethylstilbestrol 3.5712960047 14722030
MESH:D006968 Hypersensitivity, Delayed Fish Oils 4.6011484837
MESH:D006973 Hypertension Benzene 18.0917940673
MESH:D006973 Hypertension daidzein 18.0917169123
MESH:D006973 Hypertension Phenylephrine 18.0912717712 8949925
MESH:D006973 Hypertension Quercetin 18.0918356687
MESH:D006973 Hypertension Raloxifene 18.0917577099 15787275
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 18.0918670907 18850075
MESH:D006973 Hypertension valsartan 18.0912850387 18344623 10903974 20102058 11427623 16475468 12692753 18390891
MESH:D006974 Hypertension, Malignant valsartan 5.5111560862
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.2215338365
MESH:D006984 Hypertrophy Phenylephrine 3.7418502941 12791704
MESH:D007021 Hypospadias Diethylstilbestrol 8.3616002989
MESH:D007021 Hypospadias Ethinyl Estradiol 8.3616569931 16945680
MESH:D007077 Ileal Diseases Indomethacin 4.1210574470 18306037
MESH:D007079 Ileitis Indomethacin 4.4610651667 10647630 16133968
MESH:D007235 Infant, Premature, Diseases Indomethacin 4.4716133044
MESH:D007246 Infertility Diethylstilbestrol 3.5115036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.6412013081
MESH:D007248 Infertility, Male decitabine 14.2217581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 14.2217937319
MESH:D007248 Infertility, Male fulvestrant 14.2211514358
MESH:D007248 Infertility, Male sodium arsenite 14.2212646999 15346721
MESH:D007248 Infertility, Male vinclozolin 14.2216467254
MESH:D007249 Inflammation Curcumin 29.0518403477 16956363 17151092
MESH:D007249 Inflammation Flavonoids 29.0517296493
MESH:D007249 Inflammation Indomethacin 29.057812673 3291741 12568917
MESH:D007249 Inflammation Lipopolysaccharides 29.0517237260 9205823 17963957 17255318 12878042
MESH:D007249 Inflammation Mustard Gas 29.0511428620 11428647 9260866 9357497 11428631 8975870 17524151 16001271 11402378
MESH:D007249 Inflammation Nickel 29.0516166738
MESH:D007249 Inflammation Plant Extracts 29.0512787963 15997105 16366677 19332304
MESH:D007249 Inflammation polyphenols 29.0516366677
MESH:D007249 Inflammation Tamoxifen 29.0519457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 29.0512200463 12878042
MESH:D007249 Inflammation Zymosan 29.058014878 11289658
MESH:D015212 Inflammatory Bowel Diseases Curcumin 5.1418200517 18596194
MESH:D015212 Inflammatory Bowel Diseases Trinitrobenzenesulfonic Acid 5.1418200517
MESH:D007251 Influenza, Human Quercetin 8.0916624496
MESH:D007251 Influenza, Human Vitamin E 8.0916624496
MESH:D007333 Insulin Resistance Estradiol 5.0516627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 5.0516306350
MESH:D007410 Intestinal Diseases Indomethacin 16.4615610444 18236018 17994277 11855677 10210152 11686837 11713966 17329856 15831440
MESH:D007410 Intestinal Diseases pimagedine 16.4611713966
MESH:D007410 Intestinal Diseases Tretinoin 16.4617994277
MESH:D007410 Intestinal Diseases Trinitrobenzenesulfonic Acid 16.4617994277
MESH:D007414 Intestinal Neoplasms Curcumin 7.4910783313
MESH:D007414 Intestinal Neoplasms Plant Extracts 7.4912584176 12351151 12628509
MESH:D019586 Intracranial Hypertension Indomethacin 4.4715241188
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 3.8017255318
MESH:D043183 Irritable Bowel Syndrome Zymosan 4.9517553498
MESH:D007569 Jaw Abnormalities Ethanol 12.5115513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 12.5116580747
MESH:D007569 Jaw Abnormalities Tretinoin 12.5115992940 17551590
MESH:D007579 Jejunal Diseases Indomethacin 4.1210574470 18306037 16133968
MESH:D007627 Keloid Quercetin 4.0817086741
MESH:D017492 Keratosis, Seborrheic alitretinoin 4.7516144296
MESH:D007674 Kidney Diseases Cadmium 31.4816962696 16322080 16226777
MESH:D007674 Kidney Diseases Cadmium Chloride 31.4816962696
MESH:D007674 Kidney Diseases Doxorubicin 31.4815699352 15369732 16775033
MESH:D007674 Kidney Diseases Estradiol 31.4815618244
MESH:D007674 Kidney Diseases Indomethacin 31.4817190690
MESH:D007674 Kidney Diseases Potassium Dichromate 31.4819665454
MESH:D007674 Kidney Diseases Quercetin 31.4816962696
MESH:D007674 Kidney Diseases sodium arsenite 31.4820008137
MESH:D007674 Kidney Diseases valsartan 31.4816893502 12164870 10903974
MESH:D007674 Kidney Diseases Vitamin E 31.4812488133
MESH:D007676 Kidney Failure, Chronic Doxorubicin 7.4416707910
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 7.4416518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 19.5216705839
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 19.5214681315 16762066 15003126
MESH:D007680 Kidney Neoplasms Estradiol 19.5215610895
MESH:D007680 Kidney Neoplasms Ethylnitrosourea 19.5217379185
MESH:D007680 Kidney Neoplasms Tamoxifen 19.5218625569
MESH:D007680 Kidney Neoplasms Zidovudine 19.5212579204
MESH:D007859 Learning Disorders Diethylstilbestrol 6.9317184923
MESH:D007859 Learning Disorders Ethanol 6.9315451040
MESH:D007889 Leiomyoma Curcumin 8.4018555241
MESH:D007889 Leiomyoma Raloxifene 8.4016973256
MESH:D016773 Leishmaniasis, Cutaneous Allopurinol 6.689314461 12207774
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 6.6811703811 12228301 10320625
MESH:D007898 Leishmaniasis, Visceral Allopurinol 4.417498017 11332679 10449224
MESH:D007938 Leukemia arsenic trioxide 25.5315070760
MESH:D007938 Leukemia Benzene 25.5318335105 15935818 17119257 14694614
MESH:D007938 Leukemia Curcumin 25.5318462866
MESH:D007938 Leukemia decitabine 25.5318980019 19235587
MESH:D007938 Leukemia Genistein 25.5317468513 18980019
MESH:D007938 Leukemia kaempferol 25.5317468513
MESH:D007938 Leukemia Quercetin 25.5317468513
MESH:D007938 Leukemia Tretinoin 25.5317143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.2516085563
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell fludarabine 4.1017296974 17802794 18587576 17658394 18172266
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 11.6612560223 17077332
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 11.6616106398
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Zidovudine 11.6620370541
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.4216972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 6.2114633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 6.2116572323 15631656 10785260
MESH:D007951 Leukemia, Myeloid arsenic trioxide 16.2419077051
MESH:D007951 Leukemia, Myeloid Benzene 16.2417506065
MESH:D007951 Leukemia, Myeloid decitabine 16.2419117987 17236224 18454857
MESH:D007951 Leukemia, Myeloid Tretinoin 16.2416482212 16932348 19285840
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 8.7916467208 16968895 17050201 19850784 20471514
MESH:D015470 Leukemia, Myeloid, Acute Benzene 8.7919478238
MESH:D015470 Leukemia, Myeloid, Acute decitabine 8.7917679729 19387464 18704418 19010910 18460780 18206229
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 8.7918360721
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 8.7917596541 19850784 16294345
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 4.5618055864
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 9.1911468182 15213294 19035177 12712474 15336539 16891316 12018890 17712046 16112521 19075265 16331271 15622746 9834237 17107899 15748426 17649720 16966277 17869043 17217047 12679006 16330433 16823087 19225113 11161223 19642359
MESH:D015473 Leukemia, Promyelocytic, Acute Thiophenes 9.1916140954 16140955
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 9.199834237 17339181 17368321 19225113 16766008 16891316 15748426 17294898 17506722 19075265 16140955 17649720 16331271 16823087 17217047 17712046 19035177 17301526 12679006 19029980 17107899 16935935 17361223 19642359 16788101
MESH:D015458 Leukemia, T-Cell arsenic trioxide 8.8916882451
MESH:D015458 Leukemia, T-Cell Curcumin 8.8916106398
MESH:D007964 Leukocytosis Indomethacin 4.4716537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 4.8117980183
MESH:D007970 Leukopenia Lipopolysaccharides 3.8115821434
MESH:D007984 Leydig Cell Tumor vinclozolin 3.8416417039
MESH:D017880 Limb Deformities, Congenital Ethanol 6.0217676605
MESH:D017880 Limb Deformities, Congenital Tretinoin 6.029224671
MESH:D008064 Lipidoses Tamoxifen 2.4817567588 15342952
MESH:D008101 Liver Abscess, Amebic Indomethacin 4.8111479899
MESH:D008103 Liver Cirrhosis therapeutic 17133483
MESH:D008103 Liver Cirrhosis arsenite 11.1018296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 11.1011408273 17157831 17334410 11903743 21278145 16221502 17174718 16943688 16239168
MESH:D008103 Liver Cirrhosis Ethanol 11.1015289165
MESH:D008103 Liver Cirrhosis Plant Extracts 11.1017157831
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.2118295389
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 33.6317805973 14724832 18418968 16015684 18395914 18006644 15996030 17869086 17766677 15370692 17557913 18277467 12958196 12389079 15362042 14748882 15123356 12445418 16011737 17714472 15057751 20821823 18705752 18420326 16116963 16097048 10355542 14620537 12445421 12649538 17631135 18395095 17976157 18054572 12632512 12666154 16192424 17698563 15052691 18472094 18317297 17823541 17944888 15931870 15876570 17922224 18156304 18472332 18187930 15925388 18339082 14512876 18263696 14716833 15818738 18376398 15730626 18251166 18279442 12609069 12632514 16638106 12546737 16136751 18166357 16033810 18481824 11481614 12898905 17900296 13678700 14716496 12741479 17481882 18429990 12667390 17708605 17761835 18210741 17721639 15893842 15650968 12586293 16027843 17640975 15959796 17565644 15338365 18205269 16248980 15673190 17525996 18412020
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 33.6318006644 17355460 18705752
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 33.6318567088 16042886 17201889 15339415 14709902 18237412 16603200 12918455 15369754 15086199 15067225 16570917 14643895 14659978 17719030 18371158 15591649 15723089 18239293 15366600 17036385 15161499 17534399 15842777 17348192 12925901 18637143 15298665 15383259 17465448 15492853 15479170 16169303 15138612 17203207 17640959 17432682 16270385 16627068 15733078 14568256 17196135 15793283 17881167 15942678 18210741 15744066 16544323 16009107 15798949 17666798 15099470 15864749 18672772 15504291 17724770 18629640 15577212 15571005 14726149 18095165 15763062 15081153 18364076 17198567
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 33.6316595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 33.6314716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 33.6318166357
MESH:D008106 Liver Cirrhosis, Experimental Genistein 33.6317823541
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 33.6318194892
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 33.6312878042
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 33.6315474484
MESH:D008106 Liver Cirrhosis, Experimental Plant Extracts 33.6315479170
MESH:D008106 Liver Cirrhosis, Experimental Plant Preparations 33.6317724770
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 33.6312741479
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 33.6318564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 33.6312878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 33.6318397230 16248980
MESH:D008106 Liver Cirrhosis, Experimental valsartan 33.6315619341 15504291 16872305
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 33.6316169303
MESH:D008107 Liver Diseases Carbon Tetrachloride 8.8916246199 16964402 15720792 17285989 15830285
MESH:D008107 Liver Diseases Curcumin 8.8916956363
MESH:D008107 Liver Diseases Nitrofurantoin 8.8914966256
MESH:D008107 Liver Diseases Plant Extracts 8.8917034775
MESH:D008107 Liver Diseases polyphenols 8.8916698588
MESH:D008108 Liver Diseases, Alcoholic Ethanol 3.7917207112 17347304
MESH:D017093 Liver Failure Carbon Tetrachloride 3.3015123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 7.2214706259 16899240
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 7.2217457977
MESH:D008113 Liver Neoplasms 2-nitrofluorene 38.5215890375
MESH:D008113 Liver Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 38.5215890375
MESH:D008113 Liver Neoplasms Aflatoxin B1 38.5215890375 9163691 18177683 2125692
MESH:D008113 Liver Neoplasms arsenic trioxide 38.5214682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 38.5221137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 38.5219294768
MESH:D008113 Liver Neoplasms Diethylstilbestrol 38.5216712894 15890375
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 38.523113478 15890375
MESH:D008113 Liver Neoplasms pirinixic acid 38.5215890375 16377806 20007298
MESH:D008113 Liver Neoplasms Plant Extracts 38.5219168119
MESH:D008113 Liver Neoplasms Quercetin 38.5218980244
MESH:D008113 Liver Neoplasms sodium arsenite 38.5215276417 16712894
MESH:D008113 Liver Neoplasms Tamoxifen 38.5216684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 38.5216984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 26.078603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 26.0720377131
MESH:D008114 Liver Neoplasms, Experimental Benzene 26.0712562636
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 26.0712014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 26.071848544 15603536 6150874
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 26.0717085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Hexachlorobenzene 26.071423854
MESH:D008114 Liver Neoplasms, Experimental Quercetin 26.0719519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 26.0712151625
MESH:D008133 Long QT Syndrome arsenic trioxide 2.6415213294
MESH:D008171 Lung Diseases Acetylcysteine 24.6512815614
MESH:D008171 Lung Diseases chromium hexavalent ion 24.6516775837
MESH:D008171 Lung Diseases Mustard Gas 24.6518161513 18702808
MESH:D008171 Lung Diseases Nitrofurantoin 24.6514966256 9429087
MESH:D008171 Lung Diseases Ozone 24.658266340 19066396
MESH:D008171 Lung Diseases sodium arsenite 24.6519095001
MESH:D008171 Lung Diseases Vitamin E 24.6516863852
MESH:D017563 Lung Diseases, Interstitial Benzene 9.0314698565
MESH:D017563 Lung Diseases, Interstitial Nitrofurantoin 9.0318516814
MESH:D055370 Lung Injury Lipopolysaccharides 10.4721114838
MESH:D055370 Lung Injury Nitrofurantoin 10.471313237
MESH:D055370 Lung Injury Ozone 10.4720417186
MESH:D008175 Lung Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 53.7019931552 15893417 14755239 12438228 9255578 16401635 18813816 15172992 16061637 18508827 17139156
MESH:D008175 Lung Neoplasms Aflatoxin B1 53.7014755239
MESH:D008175 Lung Neoplasms alitretinoin 53.7016413115
MESH:D008175 Lung Neoplasms arsenic trioxide 53.7011798837 19825857
MESH:D008175 Lung Neoplasms arsenite 53.7016809336
MESH:D008175 Lung Neoplasms Benzene 53.7012562636
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 53.7020464547 18816296 17053015 20135361 18520028 18569708 20869020 20064080 6695378
MESH:D008175 Lung Neoplasms chromium hexavalent ion 53.7016570259 16876463
MESH:D008175 Lung Neoplasms Curcumin 53.7018462866 19359593 16243823
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 53.7016061637 11884234 19555203
MESH:D008175 Lung Neoplasms Doxorubicin 53.706189445 17418594
MESH:D008175 Lung Neoplasms Ethylnitrosourea 53.7016019985 17703301 16271038 6695378
MESH:D008175 Lung Neoplasms Indomethacin 53.7016537180 11497255 11053908
MESH:D008175 Lung Neoplasms Mustard Gas 53.708781369 3148597
MESH:D008175 Lung Neoplasms Ozone 53.708597069 7614698
MESH:D008175 Lung Neoplasms Plant Extracts 53.7020869020
MESH:D008175 Lung Neoplasms Quercetin 53.7016280456
MESH:D008175 Lung Neoplasms sodium arsenite 53.7017077188 16712894 17306315 19931552 15276417
MESH:D008175 Lung Neoplasms Tamoxifen 53.7018625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 53.7011884234 19555203
MESH:D008175 Lung Neoplasms vanadium pentoxide 53.7012376484
MESH:D008175 Lung Neoplasms Vincristine 53.7019825857 6189445
MESH:D008175 Lung Neoplasms vinyl carbamate 53.7011195469 11134547 15824018 17363558 15172992 16885199 12765245 17361011 12438228 17163412 16247444 14755239 12117777
MESH:D008175 Lung Neoplasms Vitamin E 53.7011062179
MESH:D008175 Lung Neoplasms Zidovudine 53.7018800350
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.2615166399
MESH:D008223 Lymphoma Benzene 24.7717584886 17119257
MESH:D008223 Lymphoma Curcumin 24.7718462866
MESH:D008223 Lymphoma decitabine 24.7719470736
MESH:D008223 Lymphoma Diethylstilbestrol 24.7715700306
MESH:D008223 Lymphoma Doxorubicin 24.7716098063
MESH:D008223 Lymphoma Ethylnitrosourea 24.7715790496
MESH:D008223 Lymphoma Etoposide 24.7712556972 12854902
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.0417654614
MESH:D016399 Lymphoma, T-Cell Curcumin 14.4816173963
MESH:D016399 Lymphoma, T-Cell Doxorubicin 14.4815621674
MESH:D016399 Lymphoma, T-Cell Ethylnitrosourea 14.4815375218
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 4.6116002989
MESH:D015674 Mammary Neoplasms, Animal Benzene 7.1512562636
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 7.1519428831
MESH:D008325 Mammary Neoplasms, Experimental Benzene 15.3811921183
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 15.3815458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 15.3817203775 11807958 11408345 16891317
MESH:D008325 Mammary Neoplasms, Experimental Ethylnitrosourea 15.3810767621 18041768 10838139
MESH:D008325 Mammary Neoplasms, Experimental Genistein 15.3814578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 15.3819196722 14580682 16827153 11731420 19196723
MESH:D020149 Manganese Poisoning Estradiol 9.6519453300
MESH:D020149 Manganese Poisoning Tamoxifen 9.6519453300
MESH:D008527 Medulloblastoma Tretinoin 2.3417453147
MESH:D008545 Melanoma Curcumin 9.0818462866 17885582
MESH:D008545 Melanoma decitabine 9.0816505122 17785578
MESH:D008545 Melanoma Doxorubicin 9.0816827129
MESH:D008545 Melanoma sodium arsenite 9.0816487513 19082730
MESH:D008545 Melanoma Tamoxifen 9.0819393235 12393984
MESH:D008545 Melanoma Tretinoin 9.0816752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 8.9415990972
MESH:D018328 Melanoma, Amelanotic Vincristine 8.9415990972
MESH:D008569 Memory Disorders Curcumin 6.9517263510
MESH:D008569 Memory Disorders Ethanol 6.9515451040 18411066
MESH:D008579 Meningioma Ethylnitrosourea 5.0817943659
MESH:D008591 Meningomyelocele Tretinoin 3.5516940565
MESH:D008654 Mesothelioma Doxorubicin 2.6217638057
MESH:D008679 Metaplasia Ozone 4.2010496685
MESH:D048629 Micronuclei, Chromosome-Defective Zidovudine 4.9317358032
MESH:D008881 Migraine Disorders Indomethacin 3.0111903285
MESH:D028361 Mitochondrial Diseases Doxorubicin 3.6815792986
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 4.6515863610
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 10.4116381670
MESH:D009062 Mouth Neoplasms Indomethacin 10.4112636206
MESH:D009062 Mouth Neoplasms Plant Preparations 10.4117418620
MESH:D052016 Mucositis Doxorubicin 9.4817415656
MESH:D052016 Mucositis irinotecan 9.4817159606
MESH:D009101 Multiple Myeloma arsenic trioxide 15.4719417148 11468182 15949261 19549372 14977855
MESH:D009101 Multiple Myeloma Benzene 15.4717119195
MESH:D009101 Multiple Myeloma Curcumin 15.4719372569
MESH:D009101 Multiple Myeloma decitabine 15.4718172295
MESH:D009101 Multiple Myeloma Raloxifene 15.4716497877
MESH:D009102 Multiple Organ Failure Zymosan 4.3915213630 12879239 18160304 15259001 12130978 15241586 10479408 15834315 10890648 17724436
MESH:D009134 Muscular Atrophy, Spinal Curcumin 4.0317962980
MESH:D009135 Muscular Diseases pirinixic acid 2.6416239165
MESH:D009139 Musculoskeletal Abnormalities sodium arsenate 4.0518186108
MESH:D009165 Mycobacterium Infections, Atypical marker/mechanism
MESH:D009182 Mycosis Fungoides arsenic trioxide 3.7718349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 8.8916105982 16882451
MESH:D009190 Myelodysplastic Syndromes decitabine 8.8919010910 18608210 16882708 19157545
MESH:D009190 Myelodysplastic Syndromes Tretinoin 8.8917596541
MESH:D009203 Myocardial Infarction Doxorubicin 16.2315857846 19429709
MESH:D009203 Myocardial Infarction Genistein 16.2317141266
MESH:D009203 Myocardial Infarction pirinixic acid 16.2319151258
MESH:D009203 Myocardial Infarction Pravastatin 16.2317188708
MESH:D009203 Myocardial Infarction Quercetin 16.2319595682
MESH:D009203 Myocardial Infarction Vincristine 16.2317284715
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.2812213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 14.4016810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 14.4017141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 14.4016411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 14.4019207477
MESH:D009232 Myxoma Raloxifene 4.6516343187
MESH:D009336 Necrosis 2,4-dinitrotoluene 2.9818551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 7.5216624393
MESH:D009361 Neoplasm Invasiveness Curcumin 7.5218495463
MESH:D009362 Neoplasm Metastasis Acetylcysteine 16.4514720322
MESH:D009362 Neoplasm Metastasis Doxorubicin 16.4518259882
MESH:D009362 Neoplasm Metastasis Indomethacin 16.4516537180 11239499 11053908
MESH:D009362 Neoplasm Metastasis irinotecan 16.4518259882
MESH:D009362 Neoplasm Metastasis norcantharidin 16.4515711181
MESH:D009362 Neoplasm Metastasis Tamoxifen 16.4519393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.1419410462
MESH:D009369 Neoplasms alitretinoin 18.9816946489
MESH:D009369 Neoplasms Benzo(a)pyrene 18.9811141357
MESH:D009369 Neoplasms decitabine 18.9819116145 19470736 17925555
MESH:D009369 Neoplasms Diethylstilbestrol 18.9815313581
MESH:D009369 Neoplasms pirinixic acid 18.9817405874
MESH:D009369 Neoplasms Quercetin 18.9815185748
MESH:D009369 Neoplasms sodium arsenite 18.9811559025
MESH:D009369 Neoplasms Tretinoin 18.9816946489 16594593
MESH:D009374 Neoplasms, Experimental Ethylnitrosourea 10.4516707424
MESH:D009374 Neoplasms, Experimental Indomethacin 10.4510663608 15625704
MESH:D009374 Neoplasms, Experimental sodium arsenite 10.4520056578
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 7.8612497104
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 7.8619200415 19189210 19196722
MESH:D009389 Neovascularization, Pathologic arsenite 7.2315738583
MESH:D009389 Neovascularization, Pathologic Estradiol 7.2317289903
MESH:D009395 Nephritis, Interstitial Nitrofurantoin 4.8519214031
MESH:D009401 Nephrosis Doxorubicin 3.9016899518 16636307
MESH:D009404 Nephrotic Syndrome Doxorubicin 3.2316889571 15640375
MESH:D009410 Nerve Degeneration Rotenone 3.1715790535 18619942 17356569
MESH:D009421 Nervous System Malformations Diethylstilbestrol 21.8711399458
MESH:D009421 Nervous System Malformations Estradiol 21.8711399458 16427766
MESH:D009421 Nervous System Malformations Genistein 21.8716427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 21.8714600291
MESH:D009421 Nervous System Malformations Tretinoin 21.879125849
MESH:D009423 Nervous System Neoplasms Curcumin 4.7218462866
MESH:D009436 Neural Tube Defects Acetylcysteine 20.0819446573
MESH:D009436 Neural Tube Defects arsenic trioxide 20.0810525206
MESH:D009436 Neural Tube Defects Benzene 20.0815643154
MESH:D009436 Neural Tube Defects sodium arsenate 20.0818186108 11749123 19446573 10525206
MESH:D009436 Neural Tube Defects sodium arsenite 20.0812854658
MESH:D009436 Neural Tube Defects Tretinoin 20.089142499
MESH:D009442 Neurilemmoma Ethylnitrosourea 4.5316651423 17160924 16003739
MESH:D019954 Neurobehavioral Manifestations Plant Extracts 4.3117168769
MESH:D009447 Neuroblastoma Doxorubicin 5.3215555623
MESH:D009447 Neuroblastoma irinotecan 5.328761367
MESH:D019636 Neurodegenerative Diseases Indomethacin 3.2012349958
MESH:D017599 Neuroectodermal Tumors irinotecan 8.908761367
MESH:D017599 Neuroectodermal Tumors Vincristine 8.9012837982
MESH:D020078 Neurogenic Inflammation Quercetin 3.5317929310
MESH:D009503 Neutropenia Mustard Gas 3.1516761898 7688884
MESH:D009669 Nose Neoplasms chromium hexavalent ion 4.2516876463
MESH:D009765 Obesity Curcumin 5.5919297423
MESH:D009765 Obesity pirinixic acid 5.5920558911
MESH:D009765 Obesity Plant Extracts 5.5919056576 20132043
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.276374098
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 6.5516049721 12819281
MESH:D009784 Occupational Diseases Benzene 6.5517119257 16737584 17178637 15727169 15612468 15935809 15576619 15913788 17479406
MESH:D009837 Oligodendroglioma Ethylnitrosourea 5.0817160924
MESH:D010003 Osteoarthritis Indomethacin 3.067009135
MESH:D010024 Osteoporosis Curcumin 11.8818719352
MESH:D010024 Osteoporosis Genistein 11.8819401787
MESH:D010024 Osteoporosis kaempferol 11.8816756079
MESH:D010024 Osteoporosis Raloxifene 11.8819059307 17882678 15775268
MESH:D015663 Osteoporosis, Postmenopausal Genistein 12.1316169203
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 12.1319495926
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 12.1317893378 15758505 15579764 17823083
MESH:D012516 Osteosarcoma Doxorubicin 3.3715930896
MESH:D010051 Ovarian Neoplasms arsenic trioxide 23.5619769630 16624393 12452020
MESH:D010051 Ovarian Neoplasms Benzene 23.5612562636
MESH:D010051 Ovarian Neoplasms Curcumin 23.5618462866 19020741
MESH:D010051 Ovarian Neoplasms decitabine 23.5619259094 19331143
MESH:D010051 Ovarian Neoplasms Estradiol 23.5619401270
MESH:D010051 Ovarian Neoplasms Genistein 23.5619005980
MESH:D010051 Ovarian Neoplasms Quercetin 23.5619005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 23.5615276417 17306315
MESH:D010051 Ovarian Neoplasms Tretinoin 23.5616936753
MESH:D010146 Pain Indomethacin 4.5713679232 17440234 3291741 17627676
MESH:D010146 Pain Tretinoin 4.5716870215
MESH:D010149 Pain, Postoperative Indomethacin 3.7818702446 12538197
MESH:D010190 Pancreatic Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 21.7212384795
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 21.7215580305
MESH:D010190 Pancreatic Neoplasms Curcumin 21.7219401701 17440100 19196508
MESH:D010190 Pancreatic Neoplasms decitabine 21.7219294695
MESH:D010190 Pancreatic Neoplasms Ethanol 21.7212384795
MESH:D010190 Pancreatic Neoplasms Etoposide 21.7219003803
MESH:D010190 Pancreatic Neoplasms Quercetin 21.7216965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 21.7215976015
MESH:D010195 Pancreatitis Indomethacin 6.1217883296 15028970
MESH:D010195 Pancreatitis Trinitrobenzenesulfonic Acid 6.1217698068
MESH:D016584 Panic Disorder Ethinyl Estradiol 2.8611578682
MESH:D010212 Papilloma Hydrogen Peroxide 6.8312065085
MESH:D010212 Papilloma Plant Extracts 6.8316517061 15173996
MESH:D010235 Paraganglioma arsenic trioxide 3.3319927285
MESH:D010257 Paraneoplastic Syndromes Indomethacin 4.8116537180
MESH:D010300 Parkinson Disease Rotenone 2.5811535288 19114014 11445065 16140633 16412576 15451049 19232380 18191903 18619942
MESH:D020734 Parkinsonian Disorders Indomethacin 6.7612349958
MESH:D020734 Parkinsonian Disorders Rotenone 6.7618197244 15574749 15927086 15795934
MESH:D051302 Paroxysmal Hemicrania Indomethacin 4.8111903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.3412520081
MESH:D010437 Peptic Ulcer Indomethacin 4.2611148446
MESH:D010518 Periodontitis Indomethacin 4.0117225004
MESH:D016491 Peripheral Vascular Diseases Cadmium 4.4915687053
MESH:D010538 Peritonitis Ozone 7.5516369182
MESH:D010538 Peritonitis Zymosan 7.5517826846 19641140 18977430 18760300 15259001 17371808 19088179 11985352 15979727 14761945 18557954
MESH:D003557 Phyllodes Tumor Doxorubicin 4.2517983394
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.2714722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 3.8016977796 15687265
MESH:D010997 Pleural Neoplasms Doxorubicin 4.2517638057
MESH:D011014 Pneumonia Lipopolysaccharides 8.1712224865 11605937
MESH:D011014 Pneumonia Ozone 8.1718007984 18929643 18381685
MESH:D011041 Poisoning Mustard Gas 2.9915727166
MESH:D011085 Polycystic Ovary Syndrome Flutamide 4.2015356085
MESH:D017499 Porokeratosis alitretinoin 5.1016144296
MESH:D017119 Porphyria Cutanea Tarda Hexachlorobenzene 8.299918132
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 8.2918163543
MESH:D011230 Precancerous Conditions Quercetin 3.2119056647
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Vincristine 4.0521297632
MESH:D011248 Pregnancy Complications Nitrofurantoin 4.9419789166
MESH:D047928 Premature Birth Indomethacin 4.2617000239
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 11.2017184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 11.2011896295 11118676 11222880 11399792
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 11.2018042343 18220299 19015723
MESH:D055728 Primary Myelofibrosis decitabine 3.8617616702
MESH:D011469 Prostatic Diseases vinclozolin 4.0418220299
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.0720887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 7.1219131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 7.1217292933
MESH:D011471 Prostatic Neoplasms Cadmium 7.1217075824
MESH:D011471 Prostatic Neoplasms Curcumin 7.1211398177 12497104 10851300 18156803 18769126 15129424 18226269
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 7.1217136230 15846301 15046698
MESH:D011471 Prostatic Neoplasms Doxorubicin 7.1215749863 16729912 16888761 18437689 15897917 16868541
MESH:D011471 Prostatic Neoplasms Estradiol 7.1216740699
MESH:D011471 Prostatic Neoplasms Etoposide 7.1217172428
MESH:D011471 Prostatic Neoplasms Flutamide 7.123169114
MESH:D011471 Prostatic Neoplasms Genistein 7.1215378649 16925846 15256057
MESH:D011471 Prostatic Neoplasms Plant Extracts 7.1217804756 14666653
MESH:D011471 Prostatic Neoplasms Quercetin 7.1217292933 14715546
MESH:D011471 Prostatic Neoplasms Raloxifene 7.1215731164 16536755 16220300
MESH:D011471 Prostatic Neoplasms sodium arsenite 7.1216039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 7.1215067354
MESH:D011471 Prostatic Neoplasms Vitamin E 7.1215084515
MESH:D011472 Prostatitis vinclozolin 4.0418629315
MESH:D011507 Proteinuria Indomethacin 10.8711849393
MESH:D011507 Proteinuria Tretinoin 10.8716636307
MESH:D011507 Proteinuria valsartan 10.8717664856 18344623 12164870
MESH:D011537 Pruritus Ethinyl Estradiol 6.6116919318 15861022
MESH:D011537 Pruritus Mustard Gas 6.6118058305
MESH:D011625 Pterygium Tretinoin 3.9016723453
MESH:D011654 Pulmonary Edema Nitrofurantoin 4.899429087
MESH:D011656 Pulmonary Emphysema Curcumin 3.7319168576
MESH:D011658 Pulmonary Fibrosis Mustard Gas 7.0317620002 17894541 17720292 10334151 17266442
MESH:D011658 Pulmonary Fibrosis Nitrofurantoin 7.031551546
MESH:D011658 Pulmonary Fibrosis valsartan 7.0317241526
MESH:D011693 Purpura Raloxifene 4.6515770314
MESH:D051437 Renal Insufficiency Doxorubicin 3.3617922066
MESH:D015427 Reperfusion Injury pirinixic acid 1.8719058328
MESH:D012128 Respiratory Distress Syndrome, Adult Acetylcysteine 6.7612210543
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 6.7618379247 10666014
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.0910835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 2.9918990726
MESH:D012208 Rhabdomyosarcoma decitabine 8.1919155313
MESH:D012208 Rhabdomyosarcoma Tretinoin 8.1916116481 16283617
MESH:D012509 Sarcoma Curcumin 6.9518462866
MESH:D012509 Sarcoma Doxorubicin 6.9515625365 18313854 16767912 17203757 15675481 17710206
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 17.7616646077
MESH:D012512 Sarcoma, Ewing's Dactinomycin 17.7614601052
MESH:D012512 Sarcoma, Ewing's Doxorubicin 17.7616326096 14601052
MESH:D012512 Sarcoma, Ewing's Etoposide 17.7614601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 3.9017846226
MESH:D012554 Schistosomiasis japonica Quercetin 4.6416862918
MESH:D012640 Seizures 2,4-dinitrotoluene 8.9518551238
MESH:D012640 Seizures Ethanol 8.959754883
MESH:D012640 Seizures Mecamylamine 8.9512660363
MESH:D012640 Seizures Nitrous Oxide 8.959754883
MESH:D018805 Sepsis Curcumin 7.1818389075
MESH:D018805 Sepsis Zymosan 7.1811441115
MESH:D012852 Sinusitis Phenylephrine 3.827327846
MESH:D012871 Skin Diseases Mustard Gas 3.9012880345 16961503 15451306
MESH:D012871 Skin Diseases Vitamin E 3.9018709164
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 22.9310029692 19755658
MESH:D012878 Skin Neoplasms Doxorubicin 22.9315692506
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 22.9312065085
MESH:D012878 Skin Neoplasms Plant Extracts 22.9316517061 15173996
MESH:D012878 Skin Neoplasms sodium arsenite 22.9318572023 19524636
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 22.938532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 22.9316192470
MESH:D012878 Skin Neoplasms Tretinoin 22.9316467112
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 3.7016767912 17203757 15625365
MESH:D013088 Spermatocele Diethylstilbestrol 14.9416709447 16002989
MESH:D013088 Spermatocele Ethinyl Estradiol 14.9416709447
MESH:D013088 Spermatocele Tamoxifen 14.9416709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.1619457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.0712854658
MESH:D013158 Splenic Diseases Dimethylnitrosamine 4.3712587719
MESH:D013272 Stomach Diseases Indomethacin 3.5415472012 18545984 10215738 16280098 10192188 16184426 18209964 16113693 17207306 17638125 17160473 10486359 15038085
MESH:D013274 Stomach Neoplasms arsenic trioxide 15.8017007042
MESH:D013274 Stomach Neoplasms Benzene 15.8012562636
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 15.8020155912 2093021
MESH:D013274 Stomach Neoplasms decitabine 15.8019037991
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 15.8016033868
MESH:D013274 Stomach Neoplasms Ethanol 15.8018456281
MESH:D013274 Stomach Neoplasms Indomethacin 15.8015609394
MESH:D013274 Stomach Neoplasms irinotecan 15.8015723263
MESH:D013274 Stomach Neoplasms N'-nitrosonornicotine 15.8018456281
MESH:D013274 Stomach Neoplasms Tretinoin 15.8017261132
MESH:D013274 Stomach Neoplasms Zidovudine 15.8017696246
MESH:D013276 Stomach Ulcer Acetylcysteine 17.9017918041
MESH:D013276 Stomach Ulcer Curcumin 17.9016631530 19188055
MESH:D013276 Stomach Ulcer Ethanol 17.9016755016 17189318 17918041 9211565 11906479 9562338
MESH:D013276 Stomach Ulcer Indomethacin 17.9016631530 15138204 17657623 18431645 16169175 18299717 11906479 16755016 18193104 17135157 1323529 16397915 10878458 17627676 16934674 17918041 11523592 18087811 18237397 11729361 15255614 12077510 11595415 11145282 12500499 12467913 17977527 14567935 18209962 16150113 17654042 12498302 11595431 18543354 18726076 15104355 16252198 17895592 18181030 10750652 12787963 10423059
MESH:D013276 Stomach Ulcer pimagedine 17.9018209962
MESH:D013276 Stomach Ulcer Plant Extracts 17.9018237397 18193104 17135157 12787963 15255614
MESH:D020521 Stroke Raloxifene 6.2716837676
MESH:D020521 Stroke Vitamin E 6.2716517955
MESH:D013375 Substance Withdrawal Syndrome Ethanol 8.079754883
MESH:D013375 Substance Withdrawal Syndrome Nitrous Oxide 8.079754883
MESH:D015173 Supratentorial Neoplasms Vincristine 4.9912837982
MESH:D013705 Temporomandibular Joint Disorders Plant Extracts 10.2817997062
MESH:D013705 Temporomandibular Joint Disorders polyphenols 10.2817997062
MESH:D013733 Testicular Diseases phenethyl isothiocyanate 4.0715864552
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.3815821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 2.7911994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.3915669648
MESH:D013953 Thymus Neoplasms Benzene 9.2610850423
MESH:D013953 Thymus Neoplasms Ethylnitrosourea 9.2615790496
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.0012697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 14.9819014326
MESH:D013964 Thyroid Neoplasms decitabine 14.9817967635
MESH:D013964 Thyroid Neoplasms Doxorubicin 14.9817909728 16010429
MESH:D013964 Thyroid Neoplasms Indomethacin 14.9811352223 18791128 14736730
MESH:D013964 Thyroid Neoplasms Tretinoin 14.9816026305 17045167
MESH:D013978 Tibial Fractures Estradiol 10.7219048282
MESH:D013978 Tibial Fractures Raloxifene 10.7219048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.0016051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.0815213294
MESH:D014376 Tuberculosis Tretinoin 2.6116040207
MESH:D014456 Ulcer Indomethacin 4.0117380554 10574470
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 38.9316049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 38.9320435036 11780464 12973940 12845720
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 38.9317053015
MESH:D001749 Urinary Bladder Neoplasms Curcumin 38.9318593936
MESH:D001749 Urinary Bladder Neoplasms decitabine 38.9317616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 38.9316712894 17306315 16452187
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 38.9317653716
MESH:D001749 Urinary Bladder Neoplasms Nitrofurantoin 38.9315028437
MESH:D001749 Urinary Bladder Neoplasms Plant Preparations 38.9311251952
MESH:D001749 Urinary Bladder Neoplasms Quercetin 38.9316720314
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 38.9317572228
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 38.9316712894 17306315 11723127 16452187
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 38.9316712894 17572228 8653321
MESH:D014552 Urinary Tract Infections Nitrofurantoin 5.681551546
MESH:D014565 Urogenital Neoplasms Curcumin 4.3718462866
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 3.4310091137
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 11.3316175088
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 11.3311813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 11.3316129372
MESH:D014591 Uterine Diseases Diethylstilbestrol 4.2714652134
MESH:D014594 Uterine Neoplasms Benzene 11.2312562636
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 11.2316690809 15809267
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 11.2314692618
MESH:D014604 Uveal Neoplasms decitabine 9.8317785578
MESH:D014604 Uveal Neoplasms Tretinoin 9.8316752155
MESH:D014605 Uveitis Zymosan 4.5011006244
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 8.2616002989 16513791
MESH:D014625 Vaginal Neoplasms Zidovudine 8.2612579204
MESH:D014652 Vascular Diseases sodium arsenite 3.5417056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.6912125929
MESH:D054556 Venous Thromboembolism Raloxifene 4.3016837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.7314671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 7.6317638931 17334414 16364871 17678736
MESH:D018487 Ventricular Dysfunction, Left Plant Extracts 7.6318097624
MESH:D020257 Ventricular Remodeling Plant Extracts 9.9218097624
MESH:D020257 Ventricular Remodeling valsartan 9.9219027736
MESH:D014820 Vitiligo Tretinoin 3.2116761959
MESH:D014839 Vomiting Indomethacin 3.8511897121
MESH:D014846 Vulvar Neoplasms Raloxifene 4.6516343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.3415886252
MESH:D009396 Wilms Tumor Tretinoin 3.1916287080
MESH:D014947 Wounds and Injuries Plant Extracts 3.5119894650 20213670
Pathway ID Pathway Name
KEGG:04062 Chemokine signaling pathway
KEGG:05160 Hepatitis C
KEGG:04630 Jak-STAT signaling pathway
KEGG:05140 Leishmaniasis
KEGG:05162 Measles
KEGG:04380 Osteoclast differentiation
KEGG:05212 Pancreatic cancer
KEGG:05200 Pathways in cancer
REACT:16888 Signaling by PDGF
REACT:6900 Signaling in Immune system
KEGG:04620 Toll-like receptor signaling pathway
KEGG:05145 Toxoplasmosis
KEGG:05152 Tuberculosis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA36183
    • No data
    Releated disease ID Related disease Name
    PA443624Carcinoma, Renal Cell
    PA443450Asthma
    PA444818Lung Neoplasms
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    Releated drug ID Related drug Name
    PA164749376interferon alfacon-1
    PA10804imatinib
    PA451096prednisolone
    PA164749238exenatide
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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