AutismKB 2.0

Annotation Detail for STAU1


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Basic Information Top
Gene Symbol:STAU1 ( FLJ25010,STAU )
Gene Full Name: staufen, RNA binding protein, homolog 1 (Drosophila)
Band: 20q13.13
Quick LinksEntrez ID:6780; OMIM: 601716; Uniprot ID:STAU1_HUMAN; ENSEMBL ID: ENSG00000124214; HGNC ID: 11370
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of STAU1 mRNAaffects expression 21346803
D000643 Ammonium Chloride Ammonium Chloride affects the expression of STAU1 mRNAaffects expression 16483693
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of STAU1 mRNAdecreases expression 19150397
D005472 Fluorouracil Fluorouracil results in decreased expression of STAU1 mRNAdecreases expression 16709241
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of STAU1 mRNAaffects binding|increases activity|increases expression 19710929
C006253 pirinixic acid pirinixic acid results in increased expression of STAU1 mRNAincreases expression 18301758
C010327 salinomycin salinomycin results in decreased expression of STAU1 mRNAdecreases expression 19682730
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 4.417525203
MESH:D000138 Acidosis Ammonium Chloride 4.0218287403
MESH:D055371 Acute Lung Injury pirinixic acid 3.4718653653
MESH:D000230 Adenocarcinoma Fluorouracil 2.4817638652
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.9416434500
MESH:D000740 Anemia Fluorouracil 4.0215504547 17963324 16511603
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.4719483382
MESH:D001943 Breast Neoplasms Fluorouracil 2.6315136595 18608205 19217205 16595493 18357371 16110121 16557594
MESH:D001943 Breast Neoplasms salinomycin 2.6319682730
MESH:D002276 Carcinoid Tumor Fluorouracil 5.1916051944
MESH:D002277 Carcinoma Fluorouracil 3.8217121937
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 2.1117971768 17045692 18930000 16799960 17088986 16332177
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 3.1418695887
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 2.5617066447 16757204 18986760 16280240
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 3.7914694615
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.9320889678
MESH:D002779 Cholestasis pirinixic acid 3.0519176532
MESH:D003110 Colonic Neoplasms Fluorouracil 2.2718772588 17172411 17016597 17287894 17018589 16340194 16510598 17169374 15001691 17725105
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.0018802399 16524972 15289873 18949393 16331619 18288408 14970324 16391804 18509181 17255274 17401013 18448328 17454858 16282729 17695437 20501625 15148649 17594712 16303861 17016601 18383874 17094418
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 4.4515095906
MESH:D007644 Darier Disease Fluorouracil 5.2516733453
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5518249437
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 2.7021346803
MESH:D004487 Edema pirinixic acid 2.8012083418
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.7320426865
MESH:D004938 Esophageal Neoplasms Fluorouracil 4.7317638652 16337965 15173087 16481741 16785472
MESH:D005234 Fatty Liver pirinixic acid 3.0920131406 19236843
MESH:D005910 Glioma Fluorouracil 2.9716145905
MESH:D006258 Head and Neck Neoplasms Fluorouracil 3.5918337622 15162350 15102660
MESH:D006333 Heart Failure pirinixic acid 2.7120558911
MESH:D006529 Hepatomegaly pirinixic acid 3.4118467677 19772884 16221962 19176532
MESH:D006943 Hyperglycemia pirinixic acid 3.4920558911
MESH:D007333 Insulin Resistance pirinixic acid 2.8216306350
MESH:D007680 Kidney Neoplasms Fluorouracil 3.5716985049
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008113 Liver Neoplasms Fluorouracil 4.8615113037 16603448 18383874 17045692
MESH:D008113 Liver Neoplasms pirinixic acid 4.8620007298 16377806 15890375
MESH:D008175 Lung Neoplasms Fluorouracil 2.0115246190
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 5.2515086387
MESH:D008325 Mammary Neoplasms, Experimental salinomycin 3.9519682730
MESH:D009062 Mouth Neoplasms Fluorouracil 3.8718986760 16757204
MESH:D009135 Muscular Diseases pirinixic acid 3.9216239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2519151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.1916411023
MESH:D009369 Neoplasms Fluorouracil 5.4416928823 18600527 18239605
MESH:D009369 Neoplasms pirinixic acid 5.4417405874
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.6416436463
MESH:D009765 Obesity pirinixic acid 1.8720558911
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 4.4014694615
MESH:D010190 Pancreatic Neoplasms Fluorouracil 2.7516929163 19003803 15113037 16500647
MESH:D011471 Prostatic Neoplasms Fluorouracil 3.3619082440 18626508
MESH:D012004 Rectal Neoplasms Fluorouracil 4.3018722050 15538739 16160472 18286688
MESH:D015427 Reperfusion Injury pirinixic acid 2.5219058328
MESH:D013274 Stomach Neoplasms Fluorouracil 2.0017522103 18567086 16424979 19015929 15786421 17172411 17498489 16951190 19084572 18396642
MESH:D014062 Tongue Neoplasms Fluorouracil 4.2916280240
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 4.1816803524
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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